GO:0032811

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Name negative regulation of epinephrine secretion
Categary Process
Go Slim No
Go Link GO:0032811
Unique Molecular Interactions 372
Total Molecular Interactions 595
Total Single Events 6816
Pain Genes Associated 16

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of epinephrine secretion. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of epinephrine secretion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT98346 Negative_regulation of Binding of CPOX and PTGS1 1 0.10 2.91 6.54
2 INT26824 Crh Positive_regulation of Localization of Penk 7 0.54 0.42 6.49
3 INT15842 Crh Positive_regulation of Localization of Pomc 15 0.73 5 5.05
4 INT29206 Crh Regulation of Localization of POMC 4 0.64 0.96 4.68
5 INT18793 Crh Regulation of Localization of Penk 1 0.59 0 3.2
6 INT34294 Penk Positive_regulation of Localization of Crh 1 0.16 0.43 3.19
7 INT31513 Crh Regulation of POMC 3 0.29 5.06 2.78
8 INT62450 Il2 Positive_regulation of Localization of Crh 1 0.43 0.59 2.64
9 INT29446 Crh Positive_regulation of Localization of POMC 8 0.38 1.87 2.58
10 INT327940 Crh Positive_regulation of Gene_expression of F2rl1 1 0.44 5.57 2.5
11 INT21520 Crh Regulation of Pomc 3 0.22 0.4 2.45
12 INT81657 Binding of CPOX and PTGS1 5 0.15 1.9 2.37
13 INT29716 Crh Negative_regulation of Localization of Gnrh1 5 0.44 0 2.35
14 INT18791 Crh Regulation of Penk 2 0.49 0 2.15
15 INT356313 Crh Positive_regulation of Localization of Helt 1 0.02 0 2.11
16 INT30954 Crh Negative_regulation of LH 5 0.46 1.4 2.06
17 INT60626 Crh Positive_regulation of Localization of Pomc 7 0.54 2.3 1.99
18 INT163266 Crh Negative_regulation of Tyr 1 0.01 0.45 1.98
19 INT97208 Binding of Gabrg1 and Gabbr1 2 0.07 0.31 1.94
20 INT165284 Positive_regulation of Nts Positive_regulation of Crh 1 0.40 1.86 1.93
21 INT165285 Nts Positive_regulation of Crh 1 0.40 1.84 1.91
22 INT149469 Oxt Regulation of Gene_expression of Crh 1 0.45 1.2 1.91
23 INT29715 Crh Negative_regulation of Localization of LH 5 0.43 0 1.78
24 INT68709 Positive_regulation of Crh Regulation of Npr1 1 0.03 0 1.71
25 INT68710 Crh Regulation of Npr1 1 0.03 0 1.7
26 INT341372 CRX Positive_regulation of Gene_expression of Crh 1 0.04 1.81 1.7
27 INT94270 Pomc Regulation of Transcription of Crh 1 0.17 0.67 1.6
28 INT151020 Binding of Pdyn and Crh 1 0.14 0.42 1.59
29 INT356327 Crh Positive_regulation of Localization of Gabrg1 1 0.17 0 1.58
30 INT209087 Crh Positive_regulation of Ceacam3 1 0.24 1.45 1.54
31 INT166360 Negative_regulation of Crhr1 Negative_regulation of Positive_regulation of Pomc 1 0.02 0.36 1.5
32 INT59547 Avp Positive_regulation of Crh 2 0.14 1.13 1.47
33 INT199494 Crh Positive_regulation of Localization of Pdyn 1 0.02 0.43 1.4
34 INT15846 Crh Positive_regulation of Localization of ENG 3 0.07 0.42 1.38
35 INT290542 Crh Positive_regulation of Insr 1 0.02 0.36 1.36
36 INT356317 Crhr1 Regulation of Gene_expression of Cea 1 0.18 0.65 1.33
37 INT356326 Crhr1 Regulation of Gene_expression of Helt 1 0.01 0.65 1.32
38 INT132412 Negative_regulation of Ngf Negative_regulation of Ptgs1 1 0.01 0.81 1.31
39 INT62448 Il2 Positive_regulation of Crh 1 0.59 0.36 1.3
40 INT31008 Crh Positive_regulation of Pomc 3 0.49 2.31 1.28
41 INT105295 WAS Regulation of PTGS1 1 0.02 0.13 1.27
42 INT5518 Pomc Negative_regulation of Crh 2 0.36 0.42 1.26
43 INT142431 Cp Positive_regulation of Crh 1 0.31 1.49 1.26
44 INT103031 Calca Positive_regulation of Ptgs1 2 0.46 0.98 1.22
45 INT29714 Crh Regulation of Localization of LH 2 0.26 0 1.19
46 INT94498 Il1b Positive_regulation of Gene_expression of Crh 1 0.24 1.94 1.13
47 INT94496 Il6 Positive_regulation of Gene_expression of Crh 1 0.29 1.94 1.12
48 INT29713 Crh Negative_regulation of Localization of Gnrhr 1 0.39 0 1.12
49 INT209088 Binding of Ceacam3 and Crhr1 1 0.34 1.26 1.11
50 INT57982 Il1b Positive_regulation of Crh 2 0.38 0.98 1.09
51 INT70270 Binding of ADRA2B and Pnoc 2 0.02 0.15 1.08
52 INT356316 Crh Positive_regulation of Localization of Cea 1 0.34 0 1.06
53 INT38936 Binding of Avp and Crh 7 0.40 0.82 1.04
54 INT210015 Binding of Adcyap1 and Crh 1 0.47 0.88 1
55 INT5612 Cck Positive_regulation of Localization of Crh 1 0.65 0.16 1
56 INT175805 Crh Positive_regulation of Gene_expression of POMC 1 0.12 1.07 0.99
57 INT31494 Pomc Regulation of Crh 2 0.12 0.13 0.97
58 INT60213 Binding of Ptgs1 and Ptgs2 2 0.37 0.5 0.97
59 INT36002 Negative_regulation of Crh Negative_regulation of LH 2 0.29 0.66 0.96
60 INT149471 Avp Regulation of Gene_expression of Crh 1 0.45 0.6 0.96
61 INT61037 Och Positive_regulation of Ptgs1 1 0.00 0 0.95
62 INT72917 Binding of Crh and Crhr1 4 0.32 0.73 0.91
63 INT62449 Gnrh1 Regulation of Crh 1 0.40 0.34 0.91
64 INT119100 Positive_regulation of F2rl1 Positive_regulation of Positive_regulation of Ptgs1 1 0.03 0.56 0.9
65 INT66371 Pomc Regulation of Gene_expression of Crh 2 0.49 0 0.88
66 INT21006 Oprl1 Regulation of Localization of Crh 1 0.19 0 0.84
67 INT64629 Binding of Gal and Crh 1 0.18 0.1 0.83
68 INT64627 Binding of Oxt and Crh 1 0.07 0.1 0.83
69 INT122191 Binding of Crh and Ucn 4 0.36 0.79 0.82
70 INT62176 Binding of PTGS2 and Ptgs1 2 0.00 0.69 0.79
71 INT36003 Crh Positive_regulation of Localization of LH 2 0.45 0 0.79
72 INT56459 ADRA2C Positive_regulation of Localization of AHSP 1 0.23 0 0.78
73 INT79532 Crh Regulation of Ugt1a10 1 0.00 0 0.76
74 INT28620 Penk Regulation of Crh 2 0.40 0.25 0.75
75 INT137321 Gabrg1 Negative_regulation of Positive_regulation of Gabbr1 1 0.22 0 0.75
76 INT244062 Gabrg1 Regulation of Gabbr1 1 0.01 0.09 0.74
77 INT30838 Crh Negative_regulation of D230030E09Rik 1 0.17 0.1 0.73
78 INT290551 Crh Positive_regulation of Etf1 1 0.01 0.38 0.73
79 INT119314 Ptgs1 Regulation of Gene_expression of Ptger2 1 0.01 0.6 0.73
80 INT290544 Negative_regulation of Crh Positive_regulation of Insr 1 0.01 0.3 0.72
81 INT290553 Positive_regulation of Oprk1 Positive_regulation of Crh 1 0.33 0.39 0.72
82 INT290548 Positive_regulation of Crhr1 Positive_regulation of Etf1 1 0.01 0.38 0.72
83 INT5971 Il1a Positive_regulation of Crh 2 0.51 0.57 0.71
84 INT313778 Gene_expression of Crhq1 Negative_regulation of Localization of Crh 1 0.05 0.66 0.71
85 INT12022 Crh Positive_regulation of Localization of Prl 1 0.02 0.14 0.7
86 INT26198 Positive_regulation of Crh Positive_regulation of Localization of POMC 1 0.38 0 0.7
87 INT55205 Prl Positive_regulation of Localization of Crh 1 0.47 0 0.69
88 INT55209 Prl Positive_regulation of Crh 1 0.51 0 0.69
89 INT114735 Mtx1 Regulation of Ptgs1 1 0.01 0.31 0.69
90 INT253825 Cck Positive_regulation of Crh 1 0.74 0 0.69
91 INT253830 Cck Positive_regulation of Crh 1 0.38 0 0.68
92 INT122190 Binding of Crhr1 and Ucn 4 0.49 0.65 0.67
93 INT135119 Binding of Pomc and Crh 1 0.35 0 0.67
94 INT103905 Gh Positive_regulation of Positive_regulation of Crh 1 0.08 0.9 0.66
95 INT81832 Binding of ADRA2C and CRYGS 1 0.06 0 0.66
96 INT97508 Negative_regulation of Il1b Positive_regulation of Crh 1 0.31 0.89 0.65
97 INT33561 Crh Positive_regulation of POMC 3 0.45 1.19 0.64
98 INT290545 Crh Positive_regulation of Positive_regulation of Insr 1 0.02 0.06 0.64
99 INT264775 Binding of Gabbr1 and Abat 1 0.03 0 0.64
100 INT356329 Crhr1 Regulation of Cea 1 0.09 0.31 0.64
101 INT290540 Positive_regulation of Crh Positive_regulation of Insr 1 0.02 0.06 0.64
102 INT34212 PSG2 Regulation of Localization of Crh 1 0.02 0.09 0.63
103 INT34211 DNM2 Regulation of Localization of Crh 1 0.01 0.09 0.63
104 INT356314 Binding of Crhr1 and ORF61 1 0.00 0 0.63
105 INT142432 Regulation of Cp Positive_regulation of Crh 1 0.18 0.75 0.63
106 INT23576 Binding of Penk and Crh 2 0.18 0 0.62
107 INT20162 Crh Regulation of GNRH1 2 0.02 0.07 0.62
108 INT101320 Negative_regulation of Ptgs1 Positive_regulation of Ptgs2 1 0.03 0.2 0.62
109 INT27067 Crh Positive_regulation of Localization of Avp 3 0.18 0.46 0.61
110 INT91391 Crh Regulation of Localization of Gnrh1 2 0.36 1.78 0.61
111 INT55672 Ptgs1 Positive_regulation of Gene_expression of Ik 1 0.03 0.75 0.61
112 INT356328 Crh Positive_regulation of Cea 1 0.26 0.28 0.6
113 INT57246 Crh Positive_regulation of Positive_regulation of Caprin2 1 0.01 0.55 0.6
114 INT104050 Binding of Crh and Nts 1 0.40 0 0.6
115 INT59540 Crh Regulation of Gnrh1 2 0.36 2.61 0.58
116 INT356315 Crh Regulation of Cea 1 0.16 0.08 0.58
117 INT91393 Crh Positive_regulation of SST 1 0.01 0.73 0.58
118 INT54620 IL1B Positive_regulation of Crh 1 0.01 0.39 0.58
119 INT62445 Pomc Negative_regulation of Localization of Crh 1 0.12 0.07 0.58
120 INT30268 Binding of Gnrh1 and Crh 1 0.45 0.65 0.57
121 INT356311 Crh Regulation of Gabrg1 1 0.08 0.08 0.57
122 INT77367 IFNA1 Positive_regulation of Positive_regulation of Crh 1 0.05 0.76 0.57
123 INT30267 Binding of Crh and Gnrhr 1 0.33 0.65 0.57
124 INT98815 Binding of Crhr2 and Ucn 3 0.32 0.5 0.56
125 INT94499 Tnf Positive_regulation of Gene_expression of Crh 1 0.27 0.97 0.56
126 INT356321 Positive_regulation of Crhr1 Positive_regulation of Cea 1 0.19 0.37 0.56
127 INT141020 Crh Positive_regulation of Gene_expression of Pomc 1 0.05 0.17 0.55
128 INT356322 Positive_regulation of Crhr1 Positive_regulation of ORF61 1 0.00 0 0.54
129 INT76200 CASP1 Positive_regulation of Gene_expression of PTGS1 1 0.05 0.16 0.54
130 INT60627 Crh Positive_regulation of Localization of Mc2r 2 0.11 0.44 0.53
131 INT87557 Crh Positive_regulation of Prkaca 1 0.27 0 0.52
132 INT130161 IgG-2a Positive_regulation of Gene_expression of Crhr1 1 0.01 0 0.52
133 INT130158 Pomc Regulation of Gene_expression of Crhr1 1 0.20 0 0.52
134 INT130163 Pomc Positive_regulation of Gene_expression of Crhr1 1 0.15 0 0.52
135 INT130159 IgG-2a Regulation of Gene_expression of Crhr1 1 0.01 0 0.52
136 INT205030 Crh Positive_regulation of Crhr1 2 0.54 1.33 0.51
137 INT55208 Prl Negative_regulation of Localization of Crh 1 0.43 0 0.51
138 INT105849 Il1b Positive_regulation of Positive_regulation of Ptgs1 1 0.07 0.38 0.51
139 INT127337 Crh Regulation of LOC308670 1 0.01 0 0.51
140 INT78590 Nos2 Positive_regulation of PTGS1 2 0.00 0.85 0.5
141 INT62446 Il6 Positive_regulation of Crh 1 0.22 0.05 0.5
142 INT131809 Nfkb1 Positive_regulation of Gene_expression of Ptgs1 1 0.12 0.73 0.48
143 INT27066 Crh Positive_regulation of Localization of Oxt 1 0.40 0 0.48
144 INT129551 Sag Negative_regulation of Gene_expression of Ptgs1 1 0.08 0.88 0.48
145 INT59546 Avp Positive_regulation of Localization of Crh 1 0.05 0.08 0.47
146 INT59548 Negative_regulation of Avp Positive_regulation of Crh 1 0.04 0.08 0.47
147 INT28619 Negative_regulation of Penk Regulation of Crh 1 0.41 0 0.46
148 INT103026 Ptgis Positive_regulation of Ptgs1 1 0.02 0.42 0.46
149 INT103029 Calca Positive_regulation of Positive_regulation of Ptgs1 1 0.12 0.41 0.46
150 INT132580 Binding of ADRA2C and Htr1a 1 0.41 0.27 0.45
151 INT62447 Gnrh1 Regulation of Localization of Crh 1 0.40 0.17 0.45
152 INT57983 Il1b Regulation of Crh 1 0.37 0.09 0.44
153 INT57981 Regulation of Il1b Positive_regulation of Crh 1 0.22 0.1 0.44
154 INT30083 Binding of Crh and Lvp1 1 0.00 0.35 0.44
155 INT69163 Tlr4 Positive_regulation of Ptgs1 1 0.02 0.08 0.44
156 INT29254 Positive_regulation of ADRA2C Positive_regulation of Localization of GH1 1 0.13 0.06 0.44
157 INT290543 Binding of Crh and Pdyn 1 0.25 1.04 0.43
158 INT273945 Crh Positive_regulation of Gene_expression of Crem 1 0.20 0.52 0.43
159 INT53470 Acsm3 Regulation of Ptgs1 1 0.15 0 0.42
160 INT53469 Negative_regulation of Acsm3 Regulation of Ptgs1 1 0.24 0 0.42
161 INT139486 Oprm1 Positive_regulation of Crh 1 0.27 0.1 0.42
162 INT55202 Crh Positive_regulation of Negative_regulation of Prl 1 0.51 0 0.41
163 INT53471 Binding of Ptgs1 and Acsm3 1 0.17 0 0.41
164 INT91107 Positive_regulation of Ptgs1 Positive_regulation of Localization of Crh 1 0.00 0.56 0.41
165 INT273939 Positive_regulation of Crem Negative_regulation of Transcription of Crh 1 0.18 0.99 0.39
166 INT273956 Binding of Crem and Negative_regulation of Transcription of Crh 1 0.18 0.99 0.39
167 INT134167 Binding of ADRA2A and APLP1 1 0.09 0.64 0.39
168 INT122188 Binding of Crh and Ucn2 2 0.22 0.29 0.38
169 INT50553 Negative_regulation of Ptgs1 Negative_regulation of Gene_expression of Tbxa2r 1 0.02 1.37 0.38
170 INT73772 NR3C1 Regulation of Regulation of Crh 1 0.02 0.68 0.38
171 INT356319 ORF61 Regulation of Crh 1 0.00 0.1 0.38
172 INT74244 Ptgs1 Regulation of Positive_regulation of Penk 1 0.09 0.19 0.37
173 INT134168 Binding of ADRA2B and APLP1 1 0.06 0.7 0.37
174 INT25763 Crh Positive_regulation of Prkacb 1 0.56 0.07 0.37
175 INT122189 Binding of Crhr1 and Ucn2 2 0.08 0.27 0.36
176 INT41460 Crh Regulation of Pomc 1 0.10 0.1 0.36
177 INT93694 Binding of Hspa8 and Ptgs1 1 0.30 0.79 0.36
178 INT26197 Qrfp Regulation of Localization of Crh 1 0.02 0 0.36
179 INT41461 Crh Regulation of Localization of Pomc 1 0.10 0.1 0.36
180 INT66368 Pomc Regulation of Positive_regulation of Crh 1 0.36 0 0.35
181 INT167045 TRPA1 Regulation of PTGS1 1 0.19 0.1 0.35
182 INT25354 Chi3l1 Negative_regulation of Ptgs1 1 0.00 0.39 0.34
183 INT37552 Crh Regulation of Avp 1 0.22 0 0.34
184 INT5388 PTGS1 Negative_regulation of APRT 1 0.21 0.4 0.34
185 INT37551 Positive_regulation of Crh Regulation of Avp 1 0.38 0 0.34
186 INT37553 Crh Regulation of FDX1 1 0.03 0 0.34
187 INT68557 ZNF697 Negative_regulation of PTGS1 1 0.02 0.59 0.33
188 INT280838 Binding of Crh and gr 1 0.06 0 0.33
189 INT59602 Crhr1 Positive_regulation of Localization of LH 1 0.25 0 0.33
190 INT30418 Crh Negative_regulation of Localization of Gh1 1 0.41 0.72 0.33
191 INT273955 Creb1 Positive_regulation of Transcription of Crh 1 0.14 0.96 0.33
192 INT30524 Crh Regulation of Oprl1 1 0.15 0.15 0.33
193 INT82904 Crh Negative_regulation of ge 1 0.00 1.3 0.33
194 INT26196 Npy Positive_regulation of Localization of Crh 1 0.40 0 0.33
195 INT356323 Binding of ac and Crhr1 1 0.01 0 0.32
196 INT60628 Crh Positive_regulation of Pomc 1 0.52 0.17 0.32
197 INT26071 Adarb1 Regulation of Localization of Crh 1 0.01 0.21 0.32
198 INT30420 Crh Positive_regulation of Localization of Gh1 1 0.67 0.47 0.32
199 INT107944 Crh Regulation of Adarb1 1 0.06 0 0.32
200 INT115597 Avp Positive_regulation of Crh 1 0.56 0.79 0.31

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of epinephrine secretion. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of epinephrine secretion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT6580 Negative_regulation of Ptgs1 929 0.59 381.53 376.26
2 INT1562 Localization of Crh 499 0.81 126.74 236.68
3 INT2391 Negative_regulation of PTGS1 501 0.59 207.62 205.6
4 INT438 Gene_expression of Crh 376 0.78 159.11 169.17
5 INT5497 Positive_regulation of Crh 299 0.70 125.54 131.14
6 INT8413 Gene_expression of Ptgs1 248 0.78 110.17 108.58
7 INT1898 Regulation of Crh 220 0.62 61.33 102.64
8 INT940 Negative_regulation of Ptgs1 219 0.59 104.34 95.97
9 INT9196 Gene_expression of PTGS1 215 0.77 96.99 60.5
10 INT5016 Negative_regulation of Crh 129 0.59 36.74 59.28
11 INT5509 Positive_regulation of Localization of Crh 91 0.70 30.65 53.92
12 INT5759 Positive_regulation of Ptgs1 127 0.69 53.45 53.04
13 INT8465 Regulation of Ptgs1 100 0.57 36.03 44.41
14 INT5502 Positive_regulation of Gene_expression of Crh 69 0.70 43.06 42.23
15 INT43507 Gene_expression of Gabbr1 79 0.78 28.53 38.22
16 INT5507 Regulation of Localization of Crh 57 0.61 8.43 30.26
17 INT5514 Negative_regulation of Localization of Crh 64 0.58 8.12 29.29
18 INT651 Positive_regulation of PTGS1 93 0.69 37.27 29.18
19 INT2389 Regulation of PTGS1 86 0.61 31.23 28.95
20 INT16879 Binding of Crh 72 0.48 21.65 28.43
21 INT21379 Transcription of Crh 65 0.72 15.64 27.92
22 INT7584 Gene_expression of Crh 112 0.78 39.15 25.33
23 INT9886 Gene_expression of Ptgs1 92 0.77 40.66 25.31
24 INT21503 Binding of Ptgs1 45 0.48 15.6 22.29
25 INT5503 Negative_regulation of Gene_expression of Crh 38 0.59 16.82 21.34
26 INT440 Regulation of Gene_expression of Crh 44 0.62 17.71 20.73
27 INT45840 Positive_regulation of Gene_expression of Ptgs1 35 0.50 16.07 20.49
28 INT8075 Localization of Crh 64 0.81 25.41 19.45
29 INT6351 Positive_regulation of Gabbr1 40 0.64 11.99 19
30 INT9197 Binding of PTGS1 44 0.48 18.48 16.26
31 INT9751 Localization of Crhr1 26 0.78 10.47 15.69
32 INT21177 Positive_regulation of Crh 39 0.70 17.5 15.28
33 INT53080 Positive_regulation of Ptgs1 42 0.42 23.58 14.37
34 INT7585 Regulation of Crh 24 0.58 9.88 12.97
35 INT12992 Negative_regulation of Gene_expression of Ptgs1 33 0.42 20.47 11.77
36 INT20457 Regulation of Ptgs1 23 0.48 11.63 11.56
37 INT787 Localization of Ptgs1 31 0.80 12.36 11.55
38 INT104039 Positive_regulation of Crhr1 15 0.70 8.34 10.99
39 INT5476 Regulation of Gabbr1 21 0.45 4.01 10.26
40 INT6356 Binding of Gabbr1 30 0.48 4.62 9.82
41 INT37896 Positive_regulation of Gene_expression of PTGS1 37 0.67 17.28 9.27
42 INT7572 Regulation of Crhr1 8 0.45 5.6 8.93
43 INT12991 Negative_regulation of Gene_expression of PTGS1 28 0.41 13.39 8.9
44 INT23264 Negative_regulation of Positive_regulation of Ptgs1 16 0.39 8.47 8.9
45 INT52442 Binding of Ptgs1 16 0.35 9.05 8.78
46 INT6573 Regulation of Negative_regulation of Ptgs1 19 0.45 6.16 8.71
47 INT5498 Positive_regulation of Positive_regulation of Crh 19 0.70 9.82 7.97
48 INT6352 Negative_regulation of Gabbr1 7 0.59 4.84 7.93
49 INT21179 Negative_regulation of Crh 22 0.58 8.03 7.87
50 INT20234 Regulation of Gene_expression of Ptgs1 11 0.44 6.55 7.72
51 INT7570 Transcription of Crhr1 7 0.66 6.6 7.6
52 INT74326 Gene_expression of Crhr1 25 0.66 9.7 7.48
53 INT80161 Positive_regulation of Crhr1 13 0.67 9.66 7.33
54 INT49751 Negative_regulation of Positive_regulation of PTGS1 12 0.45 4.73 7.23
55 INT22336 Positive_regulation of Transcription of Crh 18 0.68 4.61 6.91
56 INT21138 Binding of ADRA2A 16 0.48 5.57 6.8
57 INT9753 Positive_regulation of Localization of Crhr1 8 0.49 1.72 6.55
58 INT85655 Gene_expression of Crhr1 17 0.68 9.34 6.31
59 INT25130 Positive_regulation of Negative_regulation of Ptgs1 14 0.50 5.07 6.29
60 INT5678 Gene_expression of ADRA2C 17 0.74 2.62 6.24
61 INT17370 Negative_regulation of Negative_regulation of Ptgs1 16 0.22 6.5 6.12
62 INT48004 Positive_regulation of Negative_regulation of PTGS1 12 0.49 4.07 5.87
63 INT43506 Regulation of Gene_expression of Gabbr1 2 0.61 4.88 5.52
64 INT18443 Positive_regulation of ADRA2C 12 0.69 2.61 5.48
65 INT22485 Negative_regulation of Positive_regulation of Crh 13 0.59 4.49 5.46
66 INT18244 Regulation of Positive_regulation of Crh 11 0.45 3.87 5.41
67 INT50491 Regulation of Gene_expression of PTGS1 17 0.47 6 5.4
68 INT22338 Negative_regulation of Transcription of Crh 11 0.43 2.09 5.24
69 INT39256 Localization of PTGS1 17 0.74 6.62 5.1
70 INT264765 Positive_regulation of Gene_expression of Gabbr1 2 0.70 4.88 5.07
71 INT97894 Positive_regulation of Gene_expression of Crh 27 0.70 11.82 4.82
72 INT18245 Negative_regulation of Localization of Crhr1 4 0.17 0.28 4.81
73 INT7568 Negative_regulation of Crhr1 8 0.43 4.63 4.77
74 INT62500 Transcription of Ptgs1 10 0.56 4.54 4.52
75 INT30160 Positive_regulation of ADRA2B 14 0.29 1.92 4.37
76 INT19777 Binding of Crh 16 0.40 6.65 4.36
77 INT117244 Gene_expression of GABBR1 5 0.33 2.19 4.36
78 INT134008 Transcription of Crh 8 0.59 6.12 3.95
79 INT63441 Regulation of Transcription of Crh 9 0.60 4.51 3.9
80 INT13134 Binding of ADRA2C 11 0.46 0.73 3.86
81 INT85537 Regulation of Crhr1 4 0.45 1.64 3.53
82 INT12388 Negative_regulation of Crhr1 17 0.59 9.47 3.33
83 INT16562 Negative_regulation of Positive_regulation of Gabbr1 5 0.43 2.67 3.24
84 INT127336 Positive_regulation of Transcription of Crhr1 3 0.48 3.37 3.19
85 INT103739 Negative_regulation of Gene_expression of Crh 19 0.59 10.19 3.17
86 INT77615 Positive_regulation of Negative_regulation of Ptgs1 6 0.50 1.55 3.11
87 INT28715 Negative_regulation of Regulation of Crh 7 0.43 0.97 3.06
88 INT54740 Positive_regulation of Localization of Crh 10 0.47 7.27 3.01
89 INT90402 Positive_regulation of Gene_expression of Ptgs1 13 0.31 4.83 2.88
90 INT9752 Regulation of Localization of Crhr1 3 0.44 0.36 2.82
91 INT54495 Binding of GABBR1 9 0.35 1.82 2.76
92 INT119855 Localization of Gabbr1 21 0.79 3.15 2.7
93 INT235853 Regulation of Gene_expression of Crh 7 0.51 1.98 2.66
94 INT5510 Negative_regulation of Negative_regulation of Crh 8 0.43 1.05 2.61
95 INT27607 Localization of Ptgs1 7 0.59 3.22 2.6
96 INT22339 Positive_regulation of Negative_regulation of Crh 5 0.67 1.36 2.59
97 INT122187 Positive_regulation of Crhr2 3 0.58 2.46 2.56
98 INT34969 Negative_regulation of Binding of Ptgs1 4 0.37 1.55 2.55
99 INT70197 Negative_regulation of Positive_regulation of Ptgs1 6 0.24 2.61 2.44
100 INT53476 Positive_regulation of Localization of Ptgs1 6 0.49 2.88 2.35
101 INT53540 Gene_expression of ADRA2B 10 0.46 1.78 2.33
102 INT114773 Negative_regulation of GABBR1 4 0.43 0.55 2.33
103 INT101955 Gene_expression of Crhr2 6 0.64 3.62 2.31
104 INT9887 Negative_regulation of Gene_expression of Ptgs1 7 0.42 2.94 2.3
105 INT95621 Gene_expression of Gck 6 0.64 1.06 2.26
106 INT88241 Positive_regulation of Positive_regulation of Ptgs1 3 0.45 1.71 2.25
107 INT129871 Positive_regulation of Gene_expression of Gck 1 0.28 0.15 2.19
108 INT54823 Phosphorylation of PTGS1 4 0.51 1.61 2.14
109 INT32557 Negative_regulation of Negative_regulation of PTGS1 8 0.43 3.44 2.1
110 INT58352 Negative_regulation of Gene_expression of Gabbr1 5 0.43 1.36 2.05
111 INT101985 Positive_regulation of Positive_regulation of Ptgs1 4 0.15 4.13 1.98
112 INT23426 Regulation of ADRA2A 8 0.48 1.81 1.88
113 INT6353 Positive_regulation of Positive_regulation of Gabbr1 2 0.46 0.79 1.85
114 INT30834 Regulation of Negative_regulation of Crh 3 0.45 0.62 1.81
115 INT53812 Regulation of Gene_expression of Ptgs1 5 0.38 0.89 1.78
116 INT64915 Regulation of Negative_regulation of PTGS1 4 0.20 1.81 1.76
117 INT142929 Regulation of Crhr2 1 0.44 1.28 1.73
118 INT29084 Regulation of Localization of Crh 4 0.29 1.24 1.72
119 INT78956 Regulation of Transcription of Ptgs1 3 0.35 1.42 1.7
120 INT59077 Transcription of PTGS1 11 0.43 2.37 1.65
121 INT60857 Negative_regulation of Regulation of Ptgs1 1 0.07 2.22 1.61
122 INT18710 Regulation of Regulation of Crh 6 0.60 0.79 1.6
123 INT43327 Positive_regulation of ADRA2A 3 0.46 1.54 1.53
124 INT205025 Positive_regulation of Positive_regulation of Crhr1 2 0.70 1.22 1.51
125 INT93792 Binding of Crhr1 4 0.48 1.32 1.49
126 INT112934 Binding of Crhr1 7 0.46 2.69 1.39
127 INT89209 Negative_regulation of Binding of Ptgs1 6 0.06 2.7 1.39
128 INT73260 Regulation of Positive_regulation of PTGS1 3 0.26 2.65 1.37
129 INT55108 Negative_regulation of Negative_regulation of Gabbr1 1 0.02 0 1.35
130 INT101954 Binding of Crhr2 4 0.31 1.23 1.34
131 INT55318 Localization of ADRA2C 3 0.73 1.39 1.3
132 INT21178 Positive_regulation of Negative_regulation of Crh 1 0.37 0.13 1.28
133 INT30161 Negative_regulation of Positive_regulation of ADRA2B 2 0.05 0.25 1.24
134 INT28888 Positive_regulation of Crhr2 6 0.68 3.8 1.23
135 INT231592 Binding of ADRA2B 5 0.18 0.13 1.23
136 INT1867 Positive_regulation of GABBR1 6 0.69 0.55 1.18
137 INT130198 Negative_regulation of Binding of PTGS1 3 0.34 2.6 1.16
138 INT105346 Gene_expression of Gck 5 0.71 3.05 1.14
139 INT6519 Positive_regulation of Gene_expression of ADRA2C 3 0.44 0.71 1.1
140 INT25043 Positive_regulation of Regulation of Crh 5 0.50 1 1.06
141 INT78353 Positive_regulation of Positive_regulation of PTGS1 4 0.27 0.95 1.06
142 INT12976 Negative_regulation of ADRA2A 4 0.50 0.16 1.01
143 INT63284 Transcription of Ptgs1 5 0.66 1.34 0.97
144 INT62980 Protein_catabolism of Ptgs1 3 0.59 0.93 0.97
145 INT6355 Regulation of Positive_regulation of Gabbr1 1 0.27 0 0.96
146 INT100142 Negative_regulation of Localization of PTGS1 2 0.35 1.71 0.91
147 INT69553 Negative_regulation of Regulation of PTGS1 1 0.16 0.78 0.91
148 INT93406 Positive_regulation of Regulation of Ptgs1 2 0.14 0 0.9
149 INT80142 Positive_regulation of Localization of PTGS1 4 0.21 1.52 0.87
150 INT58050 Regulation of Binding of Crh 2 0.42 0.84 0.86
151 INT40928 Regulation of Binding of ADRA2C 1 0.43 0 0.82
152 INT104040 Regulation of Crhr2 2 0.36 1.29 0.81
153 INT74324 Positive_regulation of Gene_expression of Crhr1 6 0.49 2.91 0.79
154 INT14130 Regulation of ADRA2C 4 0.45 1.57 0.79
155 INT77256 Negative_regulation of Gene_expression of Crhr1 5 0.40 2.52 0.77
156 INT101952 Negative_regulation of Crhr2 1 0.17 0.97 0.77
157 INT18836 Localization of ADRA2A 2 0.38 0.33 0.76
158 INT280771 Positive_regulation of Positive_regulation of Crh 2 0.41 0.21 0.76
159 INT55317 Transcription of ADRA2C 6 0.63 0.36 0.74
160 INT290527 Positive_regulation of Localization of Crhr1 1 0.37 1.4 0.74
161 INT290534 Localization of Crhr1 1 0.56 1.4 0.74
162 INT117246 Transcription of GABBR1 1 0.38 0.07 0.72
163 INT140282 Negative_regulation of Positive_regulation of Crh 3 0.39 1.09 0.71
164 INT7567 Negative_regulation of Transcription of Crhr1 1 0.37 0.48 0.71
165 INT142429 Positive_regulation of Transcription of Crh 1 0.47 0.73 0.67
166 INT93854 Positive_regulation of Transcription of Ptgs1 3 0.19 0.54 0.66
167 INT134009 Regulation of Transcription of Crh 2 0.37 1.1 0.66
168 INT28889 Transcription of Crhr2 2 0.64 1.13 0.66
169 INT25761 Regulation of Positive_regulation of Crh 1 0.45 0.15 0.65
170 INT23612 Regulation of Negative_regulation of Ptgs1 3 0.19 0.69 0.64
171 INT264628 Regulation of GABBR1 3 0.26 1.39 0.62
172 INT29256 Positive_regulation of Positive_regulation of ADRA2C 2 0.46 0.06 0.59
173 INT7563 Regulation of Transcription of Crhr1 1 0.17 0.59 0.59
174 INT251386 Transcription of Gabbr1 4 0.68 0.22 0.58
175 INT108319 Regulation of Positive_regulation of Ptgs1 1 0.16 0.08 0.57
176 INT101949 Negative_regulation of Binding of Crhr2 1 0.24 0.6 0.55
177 INT124836 Positive_regulation of Binding of Ptgs1 1 0.10 0.25 0.55
178 INT75420 Regulation of Binding of Gabbr1 1 0.01 0 0.54
179 INT30428 Positive_regulation of Binding of ADRA2A 1 0.34 0.59 0.53
180 INT87959 Phosphorylation of Ptgs1 3 0.63 0.37 0.51
181 INT18442 Negative_regulation of ADRA2C 2 0.49 0.61 0.51
182 INT356301 Negative_regulation of Positive_regulation of Crhr1 1 0.19 0.44 0.5
183 INT68529 Negative_regulation of ADRA2B 3 0.14 0.79 0.47
184 INT91220 Positive_regulation of Binding of Ptgs1 1 0.02 0.76 0.47
185 INT29102 Transcription of ADRA2A 2 0.27 0.83 0.46
186 INT39228 Regulation of Regulation of Ptgs1 2 0.39 0.38 0.45
187 INT61414 Positive_regulation of Gene_expression of ADRA2B 2 0.18 0.13 0.44
188 INT19776 Positive_regulation of Binding of Crh 1 0.43 0 0.44
189 INT65348 Negative_regulation of Regulation of Gabbr1 1 0.16 0 0.43
190 INT143392 Transcription of Crhr1 1 0.61 0.38 0.43
191 INT148784 Negative_regulation of Crhr2 2 0.40 0.76 0.42
192 INT191930 Negative_regulation of Negative_regulation of Ptgs1 1 0.07 0.94 0.42
193 INT83897 Protein_catabolism of Crh 2 0.86 1.75 0.39
194 INT6492 Regulation of ADRA2B 2 0.06 0.31 0.38
195 INT29100 Negative_regulation of Binding of ADRA2A 1 0.19 0.84 0.37
196 INT144599 Gene_expression of Crhr2 3 0.49 2.16 0.36
197 INT105342 Positive_regulation of Gene_expression of Gck 2 0.46 0.83 0.36
198 INT105343 Negative_regulation of Gene_expression of Gck 1 0.39 0 0.36
199 INT231345 Positive_regulation of Localization of Ptgs1 1 0.16 0.82 0.36
200 INT121505 Regulation of Regulation of Crhr1 1 0.43 0.33 0.35
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