GO:0032825

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Name positive regulation of natural killer cell differentiation
Categary Process
Go Slim No
Go Link GO:0032825
Unique Molecular Interactions 41
Total Molecular Interactions 50
Total Single Events 386
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of natural killer cell differentiation. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of natural killer cell differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT194619 Il15 Positive_regulation of Gene_expression of TNF 1 0.24 2.23 1.2
2 INT167944 Binding of Oprm1 and Stat5a 1 0.00 0 0.85
3 INT172134 Binding of IL6 and IL15 2 0.01 1.18 0.72
4 INT172147 Binding of IL15 and TNF 2 0.05 1.19 0.72
5 INT126614 Ppyr1 Negative_regulation of Phosphorylation of Stat5a 1 0.27 0.1 0.64
6 INT126615 Binding of Oprd1 and Stat5a 1 0.28 0.07 0.61
7 INT329963 Binding of IL21 and IL23R 1 0.30 2.28 0.6
8 INT184130 Epo Positive_regulation of Stat5a 1 0.31 0.26 0.52
9 INT184096 Il7 Positive_regulation of Stat5a 1 0.07 0.26 0.51
10 INT184132 Il2 Positive_regulation of Stat5a 1 0.09 0.26 0.51
11 INT292627 IL21 Positive_regulation of IL4 1 0.10 0.41 0.42
12 INT300547 Il6 Positive_regulation of Il21 1 0.02 0.78 0.39
13 INT167946 Binding of SRC and Stat5b 1 0.28 0 0.38
14 INT264555 IL15 Positive_regulation of Gene_expression of BCL2 1 0.02 0.92 0.35
15 INT224691 Positive_regulation of Tlr4 Positive_regulation of Gene_expression of Il15 1 0.01 0.66 0.33
16 INT224681 Tlr2 Positive_regulation of Gene_expression of Il15 1 0.01 0.66 0.33
17 INT194614 Il15 Positive_regulation of Gene_expression of Klrk1 1 0.04 0.5 0.32
18 INT226333 IL21 Positive_regulation of Binding of STAT4 1 0.03 0.57 0.2
19 INT226346 Binding of IL21 and Positive_regulation of Positive_regulation of JAK3 1 0.08 0.48 0.18
20 INT226380 Gene_expression of IL15 Negative_regulation of Positive_regulation of CD8A 1 0.02 1.59 0.18
21 INT226359 IL21 Negative_regulation of Gene_expression of IGHE 1 0.02 0.79 0.16
22 INT289248 Il6 Positive_regulation of Gene_expression of Il21 1 0.06 0.69 0.15
23 INT184129 Socs2 Negative_regulation of Stat5a 1 0.22 0.05 0.13
24 INT292630 IL21 Positive_regulation of Gene_expression of IL9 1 0.15 0.15 0.12
25 INT184089 Gh Positive_regulation of Stat5b 1 0.13 1.3 0.1
26 INT296041 Binding of TGFB1 and IL21 1 0.01 0.05 0.08
27 INT296035 IL21 Positive_regulation of Gene_expression of IL23R 1 0.01 0.05 0.08
28 INT292629 IL21 Positive_regulation of IL12A 1 0.06 0.05 0.06
29 INT292624 IL21 Positive_regulation of Binding of IL12A 1 0.06 0.05 0.06
30 INT351012 IL2RB Positive_regulation of Gene_expression of IL15 1 0.10 0.42 0.05
31 INT230066 IL15 Positive_regulation of Gene_expression of KLRD1 1 0.01 0.37 0.03
32 INT353192 Stat5a Positive_regulation of Plxna3 1 0.01 0 0
33 INT270656 Binding of Il21 and Idd3 1 0.30 0.92 0
34 INT286766 Tusc2 Positive_regulation of Gene_expression of Il15 1 0.28 1.73 0
35 INT353190 Stat5a Positive_regulation of Cyp2c11 1 0.31 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of natural killer cell differentiation. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of natural killer cell differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT133549 Gene_expression of Il15 42 0.69 27.84 14.74
2 INT172171 Gene_expression of IL15 47 0.37 46.23 13.41
3 INT224648 Gene_expression of Il21 15 0.39 18.71 7.47
4 INT126608 Binding of Stat5a 7 0.48 0.46 4.38
5 INT126610 Phosphorylation of Stat5a 5 0.82 0.8 2.52
6 INT226453 Positive_regulation of Gene_expression of IL15 9 0.24 12.66 2.38
7 INT184234 Positive_regulation of Il15 5 0.19 4.99 2.31
8 INT194610 Positive_regulation of Gene_expression of Il15 5 0.33 3.45 2.19
9 INT171891 Regulation of Il15 3 0.18 3.78 2.02
10 INT224636 Positive_regulation of Il21 6 0.45 6.16 1.97
11 INT194609 Regulation of Gene_expression of Il15 1 0.18 3.33 1.86
12 INT181720 Regulation of IL15 9 0.20 3.65 1.79
13 INT126609 Positive_regulation of Phosphorylation of Stat5a 1 0.69 0.26 1.79
14 INT224626 Negative_regulation of Il21 3 0.10 3.51 1.67
15 INT126605 Negative_regulation of Binding of Stat5a 1 0.58 0.15 1.27
16 INT133553 Negative_regulation of Gene_expression of Il15 5 0.52 2.01 1.16
17 INT103699 Negative_regulation of IL15 5 0.24 2.42 1.12
18 INT188398 Positive_regulation of IL15 8 0.19 4.64 1.06
19 INT353937 Localization of Il21 1 0.52 2.44 1.01
20 INT226495 Gene_expression of IL21 4 0.36 1.89 0.99
21 INT224624 Binding of Il21 2 0.09 1.61 0.99
22 INT133547 Transcription of Il15 3 0.48 1.3 0.97
23 INT133558 Binding of Il15 4 0.43 1.58 0.96
24 INT194612 Negative_regulation of Il15 2 0.28 1.37 0.87
25 INT184015 Positive_regulation of Stat5a 9 0.46 3.32 0.86
26 INT167938 Positive_regulation of Phosphorylation of Stat5b 1 0.33 0 0.85
27 INT167942 Binding of Stat5b 1 0.26 0 0.82
28 INT231746 Negative_regulation of Regulation of Il15 1 0.13 1.99 0.79
29 INT292653 Positive_regulation of IL21 2 0.27 1.96 0.69
30 INT258630 Binding of IL15 3 0.24 2.2 0.65
31 INT126606 Negative_regulation of Stat5a 1 0.43 0.08 0.64
32 INT159942 Positive_regulation of Stat5a 3 0.41 0.95 0.61
33 INT126612 Negative_regulation of Phosphorylation of Stat5a 1 0.42 0.1 0.61
34 INT231743 Positive_regulation of Binding of Il21 1 0.12 1.13 0.51
35 INT226429 Regulation of IL21 2 0.04 0.74 0.49
36 INT167941 Phosphorylation of Stat5b 1 0.58 0 0.42
37 INT285554 Regulation of Transcription of IL15 1 0.15 0.61 0.4
38 INT300543 Regulation of Il21 1 0.04 0.98 0.4
39 INT285546 Regulation of Gene_expression of IL15 1 0.15 0.61 0.4
40 INT285556 Transcription of IL15 1 0.23 0.6 0.4
41 INT235498 Localization of IL15 6 0.21 2.17 0.39
42 INT353932 Positive_regulation of Gene_expression of Il21 1 0.30 0.16 0.27
43 INT226447 Binding of IL21 2 0.20 0.53 0.23
44 INT293351 Negative_regulation of Regulation of IL15 1 0.04 0.34 0.22
45 INT296060 Positive_regulation of Positive_regulation of IL21 1 0.08 0.18 0.19
46 INT167940 Regulation of Stat5b 1 0.43 0 0.19
47 INT184024 Binding of Stat5a 1 0.25 0.11 0.17
48 INT184055 Positive_regulation of Binding of Stat5a 1 0.33 0.12 0.17
49 INT350667 Positive_regulation of Transcription of Stat5a 1 0.29 0.47 0.16
50 INT226462 Localization of IL21 1 0.12 0.52 0.16
51 INT350637 Transcription of Stat5a 1 0.40 0.46 0.16
52 INT133548 Negative_regulation of Binding of Il15 1 0.38 0.13 0.11
53 INT220368 Negative_regulation of Positive_regulation of Stat5a 1 0.34 0.46 0.11
54 INT274488 Positive_regulation of Localization of IL15 1 0.07 0.9 0.1
55 INT350646 Negative_regulation of Positive_regulation of Stat5a 1 0.25 0.23 0.08
56 INT313905 Localization of Stat5a 1 0.21 0.33 0.08
57 INT184061 Negative_regulation of Stat5a 2 0.29 1.85 0.04
58 INT173796 Gene_expression of Stat5a 5 0.56 1.41 0
59 INT200803 Phosphorylation of Stat5a 2 0.59 1.23 0
60 INT200800 Positive_regulation of Phosphorylation of Stat5a 1 0.36 0.24 0
61 INT293348 Negative_regulation of Positive_regulation of IL15 1 0.04 0.12 0
62 INT200799 Positive_regulation of Gene_expression of Stat5a 1 0.36 0.37 0
63 INT183523 Transcription of Il21 1 0.52 0.53 0
64 INT353174 Gene_expression of Stat5b 1 0.48 0 0
65 INT183546 Transcription of IL21 1 0.06 0.54 0
66 INT200790 Positive_regulation of Positive_regulation of Stat5a 1 0.36 0.24 0
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