GO:0032869

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Name cellular response to insulin stimulus
Categary Process
Go Slim No
Go Link GO:0032869
Unique Molecular Interactions 2954
Total Molecular Interactions 4099
Total Single Events 32905
Pain Genes Associated 102

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cellular response to insulin stimulus. They are ordered first by their pain relevance and then by number of times they were reported for cellular response to insulin stimulus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT16531 Ghrh Positive_regulation of Localization of Gh1 31 0.64 2.12 14.2
2 INT26468 Ghrh Positive_regulation of Localization of Gh 21 0.37 3.26 9.21
3 INT132225 Negative_regulation of Binding of Akt1 and Sh2d6 1 0.10 3.92 7.2
4 INT10844 Ghrh Regulation of Gh 13 0.13 4.77 4.71
5 INT128296 Negative_regulation of IL1B Positive_regulation of Insr 1 0.10 1.36 4.52
6 INT128295 IL1B Positive_regulation of Insr 1 0.11 1.36 4.5
7 INT7022 Drd1a Positive_regulation of Npr1 6 0.05 0.26 4.32
8 INT16221 Ghrh Positive_regulation of Gh 8 0.21 1.89 4.08
9 INT11248 Gh Positive_regulation of Ghrh 2 0.26 0.09 4.04
10 INT113080 Drd1a Positive_regulation of Phosphorylation of Creb1 2 0.27 0.43 3.88
11 INT220623 Binding of Stat1 and Bace1 11 0.25 10.33 3.81
12 INT180813 Ngf Positive_regulation of Sorbs1 1 0.04 2.09 3.79
13 INT132231 Negative_regulation of Binding of Akt1 and Pik3cg 1 0.34 1.96 3.6
14 INT128293 Negative_regulation of Aldh1a1 Positive_regulation of Insr 1 0.00 0.99 3.34
15 INT128292 Nts Positive_regulation of Insr 1 0.03 0.99 3.34
16 INT128291 Vom1r68 Positive_regulation of Insr 1 0.00 0.99 3.33
17 INT128294 Aldh1a1 Positive_regulation of Insr 1 0.00 0.99 3.33
18 INT69823 Binding of GHR and RYBP 1 0.01 0 3.23
19 INT317522 Akt1 Positive_regulation of Phosphorylation of Nos1 1 0.43 0.4 3.13
20 INT118158 Binding of Prkca and Prkcz 1 0.07 1.14 2.98
21 INT168758 Hist1h1t Positive_regulation of Phosphorylation of Akt1 2 0.02 0.44 2.79
22 INT317551 Binding of Akt1 and Oprm1 1 0.19 0.21 2.74
23 INT124547 Trib3 Regulation of Regulation of Th 1 0.02 0.79 2.64
24 INT26892 OGG1 Negative_regulation of Gene_expression of Gh1 1 0.12 0 2.53
25 INT20411 Ghrh Positive_regulation of Gh1 6 0.56 0.62 2.47
26 INT121726 Ngf Positive_regulation of Phosphorylation of Akt1 1 0.37 1.4 2.34
27 INT7367 Ghrh Regulation of Localization of Gh1 5 0.49 1.55 2.25
28 INT114432 Oprl1 Positive_regulation of Akt1 1 0.18 0.08 2.2
29 INT9180 Ghrh Regulation of Localization of Gh 3 0.24 0.25 2.18
30 INT3576 Sst Negative_regulation of Localization of Gh1 6 0.23 0 2.13
31 INT26948 Pomc Positive_regulation of Localization of Gh1 2 0.22 0.15 1.99
32 INT112514 Binding of Prkaca and Trib3 1 0.03 1.18 1.9
33 INT95405 Trib3 Positive_regulation of Phosphorylation of Ephb1 3 0.08 1.33 1.89
34 INT151965 SORBS1 Positive_regulation of TRPV1 1 0.18 0 1.89
35 INT7023 Negative_regulation of Drd1a Positive_regulation of Npr1 2 0.05 0.1 1.81
36 INT132229 Binding of Akt1 and Sh2d6 1 0.09 0.98 1.8
37 INT186433 Trib3 Regulation of Phosphorylation of Creb1 1 0.03 0.32 1.71
38 INT169464 Akt1 Positive_regulation of Egfr 1 0.28 1.63 1.7
39 INT70148 Drd1a Positive_regulation of Localization of Acot1 1 0.14 0 1.7
40 INT122428 Binding of Ighm and Prkci 1 0.00 0 1.66
41 INT149680 Binding of Parp1 and Oprm1 1 0.53 0 1.66
42 INT322412 PPBP Negative_regulation of Phosphorylation of Akt1 1 0.01 0 1.65
43 INT180812 Gdnf Positive_regulation of Gene_expression of Sorbs1 1 0.02 0.83 1.61
44 INT180811 Gdnf Positive_regulation of Regulation of Sorbs1 1 0.01 0.83 1.61
45 INT288731 Binding of Got1 and Gpt 1 0.23 1.25 1.61
46 INT40827 Sstr1 Negative_regulation of Localization of Gh1 1 0.13 0 1.58
47 INT89011 Lep Positive_regulation of Insr 1 0.19 2.41 1.57
48 INT249498 Src Positive_regulation of Phosphorylation of Grin2b 1 0.22 1.11 1.54
49 INT3573 Tf Negative_regulation of Localization of Gh1 1 0.36 0 1.49
50 INT19013 Ghsr Negative_regulation of Localization of Sst 1 0.15 0 1.44
51 INT180804 Bdnf Positive_regulation of Gene_expression of Sorbs1 1 0.01 0 1.44
52 INT19012 Ghsr Negative_regulation of Localization of Sstr1 1 0.10 0 1.44
53 INT214372 Ptprq Positive_regulation of Akt1 1 0.04 0.88 1.43
54 INT214369 Pik3cb Positive_regulation of Akt1 1 0.56 0.87 1.41
55 INT34834 Ghrh Positive_regulation of Gene_expression of Gh1 2 0.65 0 1.4
56 INT180809 Ngf Positive_regulation of Positive_regulation of Sorbs1 1 0.03 0.84 1.4
57 INT180808 Ngf Positive_regulation of Gene_expression of Sorbs1 1 0.03 0.84 1.4
58 INT161191 CRX Regulation of Gene_expression of Trib3 1 0.00 2 1.38
59 INT50706 Phax Positive_regulation of Localization of Trib3 1 0.04 0.28 1.38
60 INT161185 NMS Regulation of Gene_expression of Trib3 1 0.03 2 1.38
61 INT26893 OGG1 Negative_regulation of Gh1 1 0.12 0 1.37
62 INT122430 Negative_regulation of Binding of Ighm and Prkci 1 0.00 0 1.36
63 INT290542 Crh Positive_regulation of Insr 1 0.02 0.36 1.36
64 INT168865 Cd38 Regulation of Wdtc1 1 0.03 0.12 1.35
65 INT261463 Binding of Drd1a and Sftpd 1 0.12 0.13 1.35
66 INT52568 HTR1D Regulation of Localization of Gh 2 0.20 0.16 1.34
67 INT180802 Gdnf Positive_regulation of Sorbs1 1 0.02 0.98 1.34
68 INT180807 Calca Regulation of Sorbs1 1 0.02 0 1.32
69 INT142207 Adcyap1 Positive_regulation of Localization of Gh 1 0.07 0 1.3
70 INT148778 Binding of Usf1 and Rtn1 1 0.40 0.85 1.3
71 INT95406 Trib3 Positive_regulation of Ephb1 2 0.08 0.96 1.29
72 INT148775 Binding of Calca and Usf1 1 0.43 0.85 1.29
73 INT74467 Adcyap1 Positive_regulation of Localization of Gh1 1 0.37 0 1.25
74 INT70570 su Positive_regulation of Gh 1 0.01 0.15 1.24
75 INT249487 Binding of Ephb1 and Src 1 0.17 0.74 1.23
76 INT136249 Drd1a Positive_regulation of Phosphorylation of Tff3 1 0.01 0.18 1.23
77 INT131195 Creb1 Positive_regulation of Positive_regulation of Drd1a 2 0.27 0.61 1.22
78 INT7186 Trib3 Negative_regulation of Positive_regulation of Ctsb 1 0.03 0 1.21
79 INT7184 Negative_regulation of Trib3 Negative_regulation of Positive_regulation of Ctsb 1 0.03 0 1.21
80 INT228681 Fkbp4 Negative_regulation of Trib3 1 0.00 0.57 1.2
81 INT83428 Binding of ADIPOQ and FRTS 3 0.18 2.02 1.19
82 INT98908 Binding of NTRK1 and PKLR 1 0.41 1.95 1.18
83 INT98906 Positive_regulation of Binding of NTRK1 and PKLR 1 0.56 1.95 1.18
84 INT228680 Fkbp1a Negative_regulation of Trib3 1 0.01 0.56 1.18
85 INT141246 Trib3 Regulation of Gene_expression of Th 1 0.02 0.17 1.17
86 INT153589 Binding of PRKCI and Oprm1 1 0.06 0 1.17
87 INT32480 Gh1 Positive_regulation of Gene_expression of Ghrh 1 0.35 0 1.15
88 INT69824 Negative_regulation of Binding of GHR and RYBP 1 0.01 0 1.14
89 INT348400 LPA Positive_regulation of Trib3 1 0.00 0.87 1.14
90 INT7024 Regulation of Drd1a Positive_regulation of Npr1 1 0.04 0.07 1.13
91 INT68160 Alox5 Positive_regulation of Positive_regulation of Pla2g1b 1 0.03 0.64 1.13
92 INT68157 Alox5 Positive_regulation of Positive_regulation of Pdpk1 1 0.01 0.64 1.13
93 INT68156 Pla2g1b Positive_regulation of Positive_regulation of Alox5 1 0.03 0.64 1.13
94 INT14199 GNRH1 Positive_regulation of Localization of Gh1 2 0.05 0 1.12
95 INT68154 Mthfs Positive_regulation of Pdpk1 1 0.01 0.63 1.12
96 INT68158 Pla2g1b Positive_regulation of Pdpk1 1 0.05 0.63 1.12
97 INT68159 Pla2g1b Positive_regulation of Positive_regulation of Pdpk1 1 0.05 0.64 1.12
98 INT68161 Mthfs Positive_regulation of Positive_regulation of Pla2g1b 1 0.03 0.64 1.12
99 INT68155 Pla2g1b Positive_regulation of Positive_regulation of Mthfs 1 0.03 0.64 1.12
100 INT68163 Mthfs Positive_regulation of Positive_regulation of Pdpk1 1 0.01 0.64 1.12
101 INT68165 Alox5 Positive_regulation of Pdpk1 1 0.01 0.63 1.12
102 INT249488 Positive_regulation of Binding of Ephb1 and Src 1 0.23 0.68 1.12
103 INT317548 Positive_regulation of Akt1 Positive_regulation of Prkca 1 0.15 0 1.11
104 INT317516 Binding of Oprm1 and Negative_regulation of Positive_regulation of Akt1 1 0.17 0.1 1.11
105 INT99691 Pdpk1 Positive_regulation of Positive_regulation of VEGFA 1 0.01 0.72 1.11
106 INT229913 Positive_regulation of Ntsr1 Positive_regulation of Gene_expression of Egr1 1 0.12 1.33 1.11
107 INT323175 PRKCA Positive_regulation of Akt1 1 0.02 0 1.1
108 INT74185 Cck Negative_regulation of Drd1a 1 0.30 0.1 1.1
109 INT14197 Pde2a Positive_regulation of Localization of Gh1 2 0.04 0 1.08
110 INT108547 AKT1 Regulation of MAPKAPK5 1 0.04 1.2 1.08
111 INT352453 Calca Positive_regulation of Trib3 1 0.00 0.8 1.08
112 INT33338 Adarb1 Positive_regulation of Localization of Gh1 1 0.04 0 1.08
113 INT33336 Adarb1 Positive_regulation of Negative_regulation of Gh1 1 0.03 0 1.08
114 INT33337 Adarb1 Positive_regulation of Gh1 1 0.03 0 1.08
115 INT122432 Prkci Regulation of Negative_regulation of Oprd1 1 0.01 0 1.06
116 INT119887 Binding of Atf4 and Usf1 1 0.21 0.15 1.05
117 INT119888 Binding of Creb1 and Usf1 1 0.18 0.15 1.05
118 INT180806 Ngf Positive_regulation of Regulation of Sorbs1 1 0.03 0.28 1.04
119 INT338894 TNFSF14 Negative_regulation of Gsk3a 1 0.00 0.54 1.04
120 INT151218 Negative_regulation of SIGMAR1 Negative_regulation of Positive_regulation of Akt1 1 0.00 0.26 1.03
121 INT122429 Prkci Regulation of Gene_expression of Ighm 1 0.00 0 1.02
122 INT122431 Prkci Negative_regulation of Negative_regulation of Ighm 1 0.00 0 1.02
123 INT229914 Egr1 Positive_regulation of Phosphorylation of Mapk3 1 0.46 1.03 1.02
124 INT122433 Prkci Negative_regulation of Ighm 1 0.00 0 1.02
125 INT121743 Negative_regulation of Src Negative_regulation of Ephb1 1 0.27 0 1.02
126 INT7025 Positive_regulation of Drd1a Positive_regulation of Npr1 1 0.04 0.08 1.01
127 INT317554 Akt1 Regulation of Negative_regulation of Oprm1 1 0.21 0.07 1
128 INT140653 IGF1 Negative_regulation of Protein_catabolism of PARP1 1 0.32 0.63 0.98
129 INT19758 Ghrh Positive_regulation of Positive_regulation of Gh 1 0.26 0 0.98
130 INT140068 Binding of GH1 and Ghsr 1 0.00 0.47 0.97
131 INT36682 Gh1 Regulation of Gene_expression of Gnrhr 2 0.08 0 0.96
132 INT61860 Akr1d1 Regulation of Egr1 1 0.01 0 0.96
133 INT121744 Src Positive_regulation of Positive_regulation of Ephb1 1 0.35 0 0.96
134 INT61861 Akr1d1 Regulation of Positive_regulation of Egr1 1 0.01 0 0.96
135 INT317567 Binding of Akt1 and Nos1 1 0.22 0 0.96
136 INT87854 Binding of Drd1a and Positive_regulation of Localization of Abat 1 0.08 0 0.96
137 INT36683 Gh1 Regulation of Gnrhr 3 0.08 1.25 0.95
138 INT31108 Ghrh Negative_regulation of Gh1 2 0.55 0 0.95
139 INT74184 Cck Regulation of Localization of Drd1a 1 0.32 0.06 0.95
140 INT148772 Usf1 Regulation of Calca 1 0.40 0.69 0.95
141 INT180803 Sorbs1 Regulation of Gdnf 1 0.01 0.28 0.95
142 INT62106 Ghrh Negative_regulation of Localization of Gh 1 0.06 0 0.94
143 INT62109 SLC25A4 Negative_regulation of Localization of Gh 1 0.06 0 0.94
144 INT139330 Binding of SGCG and Stat1 1 0.37 0.75 0.94
145 INT137923 VEGFA Positive_regulation of Phosphorylation of Akt1 1 0.05 0 0.93
146 INT35252 Gene_expression of Ghrh Positive_regulation of Localization of Gh1 1 0.49 0 0.93
147 INT45279 Binding of CSF2 and GHR 1 0.05 0.07 0.93
148 INT107335 Pdpk1 Positive_regulation of Regulation of Sigmar1 1 0.02 0 0.93
149 INT114883 Akt1 Regulation of Pik3r1 2 0.16 0.65 0.92
150 INT186431 Trib3 Regulation of Creb1 1 0.03 0.23 0.92
151 INT122269 Src Negative_regulation of Positive_regulation of Grin2b 1 0.27 0.44 0.92
152 INT61859 Akr1d1 Positive_regulation of Egr1 1 0.01 0 0.92
153 INT61862 Slc3a1 Positive_regulation of Egr1 1 0.05 0 0.92
154 INT199392 Pklr Positive_regulation of Prok2 1 0.34 1.3 0.91
155 INT39201 Olr824 Positive_regulation of Localization of Gh1 1 0.03 0 0.91
156 INT317541 Oprd1 Negative_regulation of Akt1 1 0.06 0 0.91
157 INT122266 Src Negative_regulation of Grin2b 1 0.27 0.43 0.91
158 INT249012 Binding of Akt1 and Gabrg1 1 0.01 0 0.9
159 INT7292 Binding of Drd1a and Penk 1 0.14 0 0.9
160 INT48341 Negative_regulation of Pde8a Regulation of Ahsg 1 0.22 0 0.9
161 INT167767 Prkcz Positive_regulation of Phosphorylation of Sigmar1 1 0.04 0.23 0.9
162 INT48342 Pde8a Regulation of Ahsg 1 0.24 0 0.9
163 INT167766 Prkcz Positive_regulation of Positive_regulation of Sigmar1 1 0.04 0.23 0.9
164 INT30411 Ghrh Regulation of Gene_expression of Gh1 1 0.40 0.12 0.9
165 INT132226 Binding of Akt1 and Pik3cg 1 0.30 0.49 0.9
166 INT52760 Oprd1 Regulation of Drd1a 1 0.02 0 0.9
167 INT54854 Sorbs1 Regulation of Ins1 1 0.34 0.23 0.9
168 INT128859 Positive_regulation of RXRA Regulation of Gene_expression of OPRM1 1 0.05 0.26 0.9
169 INT61046 Oprm1 Positive_regulation of Gh1 1 0.21 0 0.89
170 INT52762 Dll1 Regulation of Drd1a 1 0.10 0 0.89
171 INT61047 Oprm1 Positive_regulation of Localization of Gh1 1 0.29 0 0.89
172 INT295552 Binding of Ghrl and Ghsr 7 0.40 1.64 0.88
173 INT28655 Calca Negative_regulation of Localization of Gh1 1 0.34 0 0.88
174 INT44589 Negative_regulation of Oprl1 Positive_regulation of Gh1 1 0.22 0.53 0.87
175 INT199109 Binding of Akt1 and Arhgdia 1 0.02 2.73 0.87
176 INT44590 Oprl1 Positive_regulation of Gh1 1 0.23 0.53 0.87
177 INT122350 Ngf Regulation of Hsd3b1 1 0.34 0 0.87
178 INT97735 Trib3 Positive_regulation of Mapk3 1 0.05 0.66 0.87
179 INT249491 Efnb2 Positive_regulation of Phosphorylation of Src 1 0.01 0.5 0.87
180 INT199391 Pklr Positive_regulation of Prokr1 1 0.31 1.28 0.87
181 INT40742 Pomc Regulation of Localization of Gh1 1 0.37 0 0.86
182 INT196576 Trib3 Positive_regulation of Phosphorylation of Mapk9 1 0.02 0.5 0.85
183 INT105970 GH1 Regulation of Ghsr 1 0.04 1.16 0.84
184 INT261480 Negative_regulation of Trib3 Positive_regulation of Ephb1 1 0.04 0.8 0.84
185 INT29279 Binding of Drd1a and Htr1a 1 0.35 0.2 0.84
186 INT28654 Calca Regulation of Localization of Gh1 1 0.36 0 0.84
187 INT344101 Positive_regulation of Drd1a Positive_regulation of Localization of Abat 1 0.01 0 0.84
188 INT69084 Binding of Adrb1 and Positive_regulation of Positive_regulation of Pdpk1 1 0.02 0.08 0.83
189 INT116106 VEGFA Positive_regulation of AKT1 1 0.12 0.3 0.83
190 INT5103 Gal Regulation of Localization of Gh1 1 0.33 0.08 0.82
191 INT317556 Phosphorylation of Gopc Positive_regulation of Akt1 1 0.10 0.08 0.82
192 INT317514 Akt1 Regulation of Localization of Oprm1 1 0.21 0.07 0.82
193 INT186428 Trib3 Regulation of Prkcg 1 0.02 0.09 0.81
194 INT73775 Binding of GH1 and GHR 4 0.35 0.68 0.8
195 INT228255 Binding of Akt1 and Pten 2 0.43 1.78 0.8
196 INT40743 Binding of Gh1 and Pomc 1 0.22 0 0.8
197 INT114068 Agtr2 Regulation of Gene_expression of Insr 1 0.15 0.95 0.79
198 INT54800 Grin1 Regulation of Gene_expression of Gh 1 0.01 0 0.79
199 INT181616 INS Positive_regulation of IRS1 1 0.01 1 0.79
200 INT105250 Cyb5b Regulation of Localization of Gh1 1 0.00 0 0.79

Single Events

The table below shows the top 100 pain related interactions that have been reported for cellular response to insulin stimulus. They are ordered first by their pain relevance and then by number of times they were reported in cellular response to insulin stimulus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT876 Localization of Gh1 843 0.80 67.75 340.82
2 INT1893 Localization of Gh 1041 0.79 340.23 256.58
3 INT3448 Positive_regulation of Gh 521 0.69 180.03 161.18
4 INT880 Positive_regulation of Localization of Gh1 304 0.70 14.79 150.23
5 INT1530 Regulation of Gh 382 0.61 115.96 112.47
6 INT874 Positive_regulation of Gh1 244 0.70 27.17 97.98
7 INT5865 Positive_regulation of Localization of Gh 282 0.69 84.86 93.5
8 INT7180 Negative_regulation of Trib3 180 0.51 68.48 88.01
9 INT5610 Positive_regulation of Insr 140 0.69 37.26 86.24
10 INT875 Regulation of Localization of Gh1 166 0.62 12.87 84.97
11 INT10534 Positive_regulation of Trib3 209 0.60 78.75 81.48
12 INT1498 Gene_expression of Gh 521 0.75 220.84 81.16
13 INT881 Negative_regulation of Localization of Gh1 164 0.58 15.1 75.28
14 INT1497 Negative_regulation of Gh 415 0.59 192.95 74.71
15 INT5861 Gene_expression of Egr1 203 0.78 49.35 68.13
16 INT103924 Positive_regulation of Akt1 359 0.69 158.94 60.34
17 INT3161 Regulation of Localization of Gh 163 0.61 35.43 59.45
18 INT1782 Regulation of Gh1 125 0.62 22 55.74
19 INT5034 Negative_regulation of Insr 100 0.55 28.08 54.5
20 INT117713 Phosphorylation of Akt1 275 0.82 95.82 54.34
21 INT1781 Negative_regulation of Gh1 127 0.59 16.94 51.77
22 INT5858 Positive_regulation of Drd1a 66 0.69 4.51 51.73
23 INT1232 Positive_regulation of Pdpk1 78 0.42 24.33 50.17
24 INT2604 Positive_regulation of Got1 223 0.70 154.78 49.51
25 INT40777 Positive_regulation of Akt1 163 0.69 59.41 49.43
26 INT17915 Gene_expression of Insr 141 0.75 47.45 48.59
27 INT106525 Phosphorylation of Akt1 436 0.82 183.81 47.82
28 INT873 Gene_expression of Gh1 130 0.76 26.15 46.75
29 INT1894 Negative_regulation of Localization of Gh 168 0.58 64.12 43.56
30 INT18992 Negative_regulation of Pdpk1 53 0.42 19.02 40.95
31 INT67613 Positive_regulation of PPARG 94 0.70 69.15 34.38
32 INT5862 Positive_regulation of Egr1 82 0.70 30.4 33.96
33 INT114881 Gene_expression of Akt1 227 0.78 102.49 31.81
34 INT8691 Localization of Insr 85 0.80 9.27 30.32
35 INT5300 Regulation of Insr 54 0.60 11.33 29.26
36 INT112707 Negative_regulation of Akt1 89 0.59 28.85 27.76
37 INT12681 Regulation of Trib3 76 0.53 23.92 26.58
38 INT6054 Positive_regulation of Gene_expression of Egr1 67 0.70 18.45 25.93
39 INT122570 Negative_regulation of Akt1 173 0.59 91.44 25.53
40 INT67610 Positive_regulation of Pparg 53 0.70 31.91 25.2
41 INT13334 Gene_expression of Drd1a 43 0.62 7.73 24.43
42 INT40776 Gene_expression of Akt1 99 0.77 34.91 24.39
43 INT117718 Positive_regulation of Phosphorylation of Akt1 112 0.69 39.26 24.09
44 INT15326 Phosphorylation of Trib3 83 0.55 30.96 22.27
45 INT10536 Gene_expression of Trib3 67 0.66 27.08 21.58
46 INT73625 Gene_expression of PPARG 108 0.78 104.85 21.42
47 INT48769 Regulation of Pdpk1 20 0.35 9.78 20.36
48 INT89396 Phosphorylation of AKT1 225 0.82 111.66 19.61
49 INT67608 Gene_expression of Pparg 41 0.78 25.09 19.53
50 INT86187 Positive_regulation of AKT1 199 0.69 122.13 19.44
51 INT7680 Regulation of Drd1a 27 0.45 4.52 18.86
52 INT13454 Positive_regulation of Positive_regulation of Gh 49 0.68 14.53 18.49
53 INT4420 Positive_regulation of GOT1 103 0.64 88.4 18.38
54 INT133647 Negative_regulation of HDAC9 149 0.57 106.84 17.9
55 INT7020 Negative_regulation of Drd1a 25 0.57 1.84 17.1
56 INT10841 Positive_regulation of Gene_expression of Gh 101 0.59 45.39 16.96
57 INT117500 Gene_expression of Adipoq 90 0.74 67.79 16.58
58 INT2480 Negative_regulation of Got1 43 0.51 14.47 16.09
59 INT4242 Negative_regulation of Positive_regulation of Gh1 26 0.58 1.47 15.75
60 INT5859 Positive_regulation of Positive_regulation of Drd1a 20 0.55 2.05 15.61
61 INT97245 Gene_expression of AKT1 217 0.77 119.63 15.59
62 INT38253 Localization of Trib3 35 0.63 10.28 15.42
63 INT105387 Gene_expression of HIF1A 116 0.77 98.62 14.66
64 INT26975 Gene_expression of Adipoq 113 0.75 106.71 14.46
65 INT26733 Gene_expression of Pdpk1 17 0.48 5.74 13.91
66 INT14768 Negative_regulation of Positive_regulation of Insr 16 0.56 5.51 13.59
67 INT109304 Positive_regulation of Phosphorylation of Akt1 113 0.69 40.92 13.49
68 INT4298 Positive_regulation of Positive_regulation of Gh1 30 0.50 1.79 13.32
69 INT67611 Positive_regulation of Pparg 39 0.69 18.33 13.23
70 INT89842 Phosphorylation of Src 34 0.69 9.57 13.08
71 INT74838 Positive_regulation of Sorbs1 18 0.34 6.93 12.63
72 INT89395 Negative_regulation of AKT1 127 0.58 70.27 12.54
73 INT110988 Gene_expression of Insr 58 0.42 42.12 12.18
74 INT117502 Positive_regulation of Adipoq 70 0.63 40.43 12.03
75 INT8533 Regulation of Sorbs1 9 0.27 3.01 11.98
76 INT26534 Regulation of Akt1 34 0.61 14.47 11.86
77 INT7682 Binding of Drd1a 22 0.48 1.8 11.83
78 INT5630 Localization of Pdpk1 10 0.45 5.21 11.36
79 INT79685 Positive_regulation of Gene_expression of Pparg 17 0.70 14.63 11.03
80 INT17826 Positive_regulation of Pla2g1b 39 0.70 11.35 10.97
81 INT8021 Gene_expression of Enpp1 43 0.78 31.46 10.8
82 INT3851 Gene_expression of Got1 58 0.65 29.15 10.52
83 INT6574 Negative_regulation of Pla2g1b 35 0.59 11.4 10.44
84 INT100379 Positive_regulation of HIF1A 69 0.69 57.31 10.4
85 INT48131 Gene_expression of Slc2a4 32 0.78 14.64 10.16
86 INT33127 Positive_regulation of Phosphorylation of Trib3 26 0.17 14.04 10
87 INT75137 Regulation of Akt1 74 0.48 37.89 9.7
88 INT99495 Gene_expression of SRD5A1 14 0.77 5 9.21
89 INT10533 Positive_regulation of Positive_regulation of Trib3 24 0.42 6.59 9.2
90 INT11510 Negative_regulation of Positive_regulation of Gh 28 0.52 12.71 9.16
91 INT8535 Localization of Sorbs1 9 0.80 2.71 9.07
92 INT89845 Positive_regulation of Src 19 0.44 7.5 9.01
93 INT120967 Negative_regulation of Phosphorylation of Akt1 47 0.57 23.67 8.98
94 INT67612 Binding of PPARG 38 0.48 22.67 8.94
95 INT49866 Negative_regulation of Parp1 53 0.58 35.37 8.84
96 INT113845 Protein_catabolism of PARP1 54 0.88 43.86 8.77
97 INT104396 Positive_regulation of Positive_regulation of Akt1 44 0.55 14.78 8.69
98 INT123813 Positive_regulation of Parp1 74 0.70 65.36 8.56
99 INT16735 Localization of Drd1a 11 0.61 0.35 8.42
100 INT4021 Positive_regulation of PLA2G1B 35 0.70 23.27 8.2
101 INT72539 Gene_expression of Sorbs1 10 0.78 4.98 8.14
102 INT104013 Negative_regulation of Gene_expression of Pdpk1 4 0.31 2.36 7.89
103 INT1499 Negative_regulation of Gene_expression of Gh 58 0.42 25.17 7.86
104 INT106522 Negative_regulation of Phosphorylation of Akt1 65 0.58 34.44 7.83
105 INT99430 Positive_regulation of Gene_expression of Slc2a4 18 0.66 10.45 7.79
106 INT126583 Positive_regulation of PARP1 50 0.68 41.44 7.78
107 INT103659 Gene_expression of Muc4 10 0.78 7.2 7.7
108 INT6055 Transcription of Egr1 47 0.69 3.61 7.68
109 INT4022 Negative_regulation of PLA2G1B 30 0.59 10.41 7.58
110 INT103925 Negative_regulation of Positive_regulation of Akt1 32 0.58 15.19 7.39
111 INT103399 Positive_regulation of Positive_regulation of Pparg 11 0.66 7 7.36
112 INT30920 Positive_regulation of Gene_expression of Insr 14 0.66 2.91 7.32
113 INT4299 Positive_regulation of Gene_expression of Gh1 27 0.50 5.24 7.31
114 INT36405 Positive_regulation of Insr 26 0.66 24.5 7.24
115 INT125136 Regulation of Adipoq 24 0.56 16.82 7.23
116 INT138922 Positive_regulation of Stat1 57 0.69 28.35 7.2
117 INT6057 Negative_regulation of Gene_expression of Egr1 17 0.57 4.17 7.17
118 INT126748 Positive_regulation of Positive_regulation of Akt1 26 0.55 11.15 7.08
119 INT47707 Negative_regulation of Egr1 9 0.41 0.17 7.03
120 INT38254 Positive_regulation of Localization of Trib3 14 0.45 6.14 6.99
121 INT878 Regulation of Gene_expression of Gh1 13 0.43 1.13 6.98
122 INT71824 Phosphorylation of Pdpk1 14 0.38 4.9 6.86
123 INT24622 Positive_regulation of Localization of Insr 15 0.69 0.32 6.85
124 INT4208 Regulation of Got1 23 0.44 6.72 6.62
125 INT118151 Positive_regulation of Prkcz 5 0.12 2.35 6.41
126 INT28861 Binding of Gh 61 0.46 25.61 6.38
127 INT5860 Regulation of Gene_expression of Egr1 20 0.62 3.02 6.38
128 INT192225 Gene_expression of HDAC9 35 0.58 32.82 6.36
129 INT116641 Phosphorylation of Gsk3a 12 0.71 4.3 6.22
130 INT137454 Gene_expression of ADIPOQ 88 0.78 85.32 6.2
131 INT146043 Positive_regulation of Gene_expression of Adipoq 39 0.67 29.93 6.12
132 INT163756 Phosphorylation of Stat1 45 0.82 14.51 6.11
133 INT117721 Positive_regulation of Gene_expression of Akt1 22 0.69 6.26 6.08
134 INT114882 Positive_regulation of Gene_expression of Akt1 45 0.69 21.29 6.06
135 INT67609 Binding of Pparg 17 0.46 9.53 6.06
136 INT10843 Regulation of Regulation of Gh 14 0.22 5.56 5.93
137 INT100078 Positive_regulation of Positive_regulation of PPARG 11 0.70 3.6 5.86
138 INT138915 Gene_expression of Stat1 144 0.77 69.53 5.85
139 INT224530 Positive_regulation of Enpp1 12 0.70 7.03 5.82
140 INT55077 Positive_regulation of Positive_regulation of Pdpk1 6 0.26 1.77 5.78
141 INT32611 Phosphorylation of Insr 13 0.80 4.18 5.77
142 INT3614 Negative_regulation of Gene_expression of Gh1 16 0.42 6.8 5.74
143 INT9895 Binding of GHR 18 0.36 4.8 5.65
144 INT17828 Gene_expression of Pla2g1b 18 0.70 6.22 5.58
145 INT14769 Positive_regulation of Positive_regulation of Insr 10 0.43 2.66 5.55
146 INT18366 Negative_regulation of Positive_regulation of Drd1a 6 0.42 0.49 5.54
147 INT68465 Positive_regulation of Gene_expression of Pdpk1 7 0.19 2.35 5.49
148 INT50704 Binding of Trib3 13 0.31 6.33 5.46
149 INT112713 Gene_expression of Hif1a 24 0.75 20.48 5.45
150 INT100222 Binding of Src 9 0.26 5.41 5.37
151 INT18661 Localization of Ghsr 32 0.78 3.19 5.2
152 INT47704 Regulation of Egr1 17 0.60 2.43 5.18
153 INT27415 Negative_regulation of Positive_regulation of Got1 15 0.51 10.99 5.14
154 INT97692 Positive_regulation of HDAC9 17 0.45 14.88 5.11
155 INT47706 Negative_regulation of Positive_regulation of Egr1 9 0.41 6.11 5.1
156 INT117499 Negative_regulation of Adipoq 28 0.56 24.15 5.07
157 INT114058 Negative_regulation of Gene_expression of Insr 13 0.31 9.23 4.97
158 INT4611 Transcription of Gh1 12 0.68 1.04 4.97
159 INT51734 Negative_regulation of Localization of Trib3 10 0.19 2.53 4.97
160 INT89844 Positive_regulation of Phosphorylation of Src 10 0.43 4.71 4.95
161 INT100220 Negative_regulation of Src 13 0.41 6.37 4.93
162 INT105336 Regulation of AKT1 52 0.56 32.53 4.89
163 INT10115 Gene_expression of INSR 31 0.75 11.98 4.86
164 INT51392 Negative_regulation of Insr 18 0.27 14.75 4.84
165 INT51944 Positive_regulation of Transcription of Egr1 12 0.49 1.96 4.72
166 INT134657 Localization of Akt1 37 0.68 11.58 4.62
167 INT24620 Negative_regulation of Gene_expression of Insr 14 0.39 6.98 4.61
168 INT128746 Negative_regulation of Gsk3a 11 0.52 8.43 4.61
169 INT72538 Negative_regulation of Sorbs1 7 0.59 4.49 4.61
170 INT149091 Gene_expression of Ghsr 42 0.76 5.11 4.6
171 INT342801 Negative_regulation of Transcription of Muc4 1 0.04 0.82 4.56
172 INT48567 Transcription of Drd1a 7 0.51 2.44 4.54
173 INT24813 Negative_regulation of Positive_regulation of Trib3 10 0.16 1.3 4.48
174 INT113078 Phosphorylation of Drd1a 4 0.30 0.77 4.45
175 INT122569 Negative_regulation of Gene_expression of Akt1 34 0.54 17.15 4.44
176 INT73626 Positive_regulation of Gene_expression of PPARG 22 0.70 18.82 4.4
177 INT168151 Gene_expression of Sgk1 10 0.76 5.58 4.35
178 INT16220 Negative_regulation of Regulation of Gh 13 0.42 3.59 4.33
179 INT79692 Negative_regulation of PPARG 24 0.59 16 4.31
180 INT13333 Regulation of Gene_expression of Drd1a 8 0.36 3.37 4.28
181 INT112704 Positive_regulation of Hif1a 25 0.67 21.49 4.23
182 INT51084 Binding of Insr 13 0.30 4.25 4.23
183 INT109450 Positive_regulation of Phosphorylation of AKT1 62 0.64 25.18 4.21
184 INT75136 Binding of Akt1 27 0.27 8.81 4.15
185 INT230796 Phosphorylation of Irs1 70 0.81 31.73 4.13
186 INT10842 Transcription of Gh 18 0.64 2.94 4.13
187 INT1231 Negative_regulation of Positive_regulation of Pdpk1 6 0.35 1.88 4.13
188 INT95512 Transcription of Ghr 24 0.69 3.1 4.12
189 INT83035 Binding of INSR 16 0.47 9.29 4.11
190 INT32205 Regulation of Positive_regulation of Trib3 9 0.11 2.82 4.1
191 INT139898 Negative_regulation of Positive_regulation of Akt1 15 0.42 4.66 4.06
192 INT72936 Gene_expression of Pparg 39 0.77 19.01 4.02
193 INT112070 Negative_regulation of Gene_expression of Pparg 6 0.59 3.72 3.96
194 INT19104 Regulation of Gene_expression of Gh 24 0.40 8.42 3.88
195 INT11605 Regulation of Positive_regulation of Gh 10 0.45 2.08 3.85
196 INT83431 Binding of ADIPOQ 35 0.48 33.63 3.83
197 INT123502 Binding of Egr1 11 0.35 6.7 3.77
198 INT10992 Gene_expression of PARP1 32 0.76 22.22 3.74
199 INT10535 Positive_regulation of Gene_expression of Trib3 13 0.59 4.93 3.74
200 INT99889 Transcription of SRD5A1 5 0.71 1.45 3.74
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