GO:0032925

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Name regulation of activin receptor signaling pathway
Categary Process
Go Slim No
Go Link GO:0032925
Unique Molecular Interactions 62
Total Molecular Interactions 74
Total Single Events 371
Pain Genes Associated 10

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of activin receptor signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported for regulation of activin receptor signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT228680 Fkbp1a Negative_regulation of Trib3 1 0.01 0.56 1.18
2 INT86150 Inhba Positive_regulation of Gene_expression of Calca 1 0.09 0.61 0.81
3 INT20761 INHBA Regulation of Localization of GNRH1 1 0.02 0 0.46
4 INT291616 Cby1 Positive_regulation of Gene_expression of Smad7 1 0.00 0.79 0.38
5 INT153460 Inhba Positive_regulation of Gene_expression of Ctgf 1 0.77 1.14 0.19
6 INT207776 Binding of FKBP1A and RYR1 1 0.05 0.59 0.12
7 INT228808 Smad7 Regulation of Rgs1 1 0.19 0.24 0.09
8 INT228812 Smad7 Regulation of Stap1 1 0.00 0.24 0.09
9 INT134837 TGFB1 Regulation of SMAD7 1 0.34 0.68 0.08
10 INT134833 TGFB1 Regulation of Gene_expression of SMAD7 1 0.34 0.69 0.08
11 INT134838 TGFB1 Positive_regulation of SMAD7 1 0.52 0.79 0.08
12 INT303562 Binding of Fgf10 and Fgfr2 1 0.40 0.88 0.07
13 INT222416 Tlr4 Positive_regulation of Gene_expression of Inhba 1 0.00 0.29 0.06
14 INT222463 Inhba Positive_regulation of Gene_expression of Fst 1 0.01 0 0.05
15 INT185037 INHBA Negative_regulation of Inhba 1 0.26 0.32 0.05
16 INT293360 Binding of CSH1 and FKBP1A 1 0.00 0.14 0.05
17 INT207760 Fkbp1a Regulation of MSMB 1 0.12 0.69 0.04
18 INT353287 Prdx2 Positive_regulation of Phosphorylation of Smad7 1 0.22 0.06 0.03
19 INT353291 Prdx2 Positive_regulation of Smad7 1 0.31 0.06 0.03
20 INT293358 Binding of FKBP1A and CABIN1 1 0.00 0.07 0.03
21 INT303563 Binding of Fgf10 and Dysf 1 0.00 0.44 0.03
22 INT353288 Smad7 Negative_regulation of Phosphorylation of Tgif1 1 0.08 0.06 0.03
23 INT120077 Gene_expression of Smad7 Negative_regulation of Positive_regulation of Itk 1 0.02 0.27 0
24 INT197808 Binding of MEN1 and NME1 1 0.00 1.81 0
25 INT197809 Binding of MEN1 and VIM 1 0.04 0.52 0
26 INT265231 Binding of FKBP1A and TGFBR1 1 0.11 0.35 0
27 INT293355 Binding of Fkbp1a and CABIN1 1 0.00 0.12 0
28 INT197810 Binding of MEN1 and MUC1 1 0.06 0.47 0
29 INT273116 Binding of Fkbp1a and Mtor 1 0.37 0 0
30 INT218663 Olr811 Positive_regulation of Gene_expression of Smad7 1 0.01 0.45 0
31 INT197816 Binding of MEN1 and NFKB1 1 0.05 0.07 0
32 INT197813 Binding of AMBP and MEN1 1 0.00 0.51 0
33 INT134836 Binding of SMAD7 and YAP1 1 0.53 0.89 0
34 INT222539 Negative_regulation of Binding of Inhba and Acvr2a 1 0.01 0 0
35 INT310188 Binding of Adcyap1r1 and Smad7 1 0.00 0 0
36 INT293354 Binding of CSH1 and Fkbp1a 1 0.00 0.12 0
37 INT347155 Mirlet7a-1 Negative_regulation of Smad7 1 0.10 0 0
38 INT265233 Binding of APC and FKBP1A 1 0.08 0.41 0
39 INT197817 Binding of JUND and MEN1 1 0.18 0.14 0
40 INT222504 Binding of Inhba and Acvr2a 1 0.01 0 0
41 INT197844 Binding of MEN1 and Nfkb1 1 0.06 0.26 0
42 INT265234 Binding of FKBP1A and SGCG 1 0.03 0.35 0
43 INT293366 Binding of CABIN1 and Fkbp1a 1 0.00 0.05 0
44 INT265232 Regulation of Binding of APC and FKBP1A 1 0.08 0.41 0
45 INT202675 Fgf10 Positive_regulation of Fgfr2 1 0.45 0.07 0
46 INT271999 Binding of Fkbp1a and Positive_regulation of Negative_regulation of Mtor 1 0.00 0.18 0
47 INT190681 Binding of Bcl2 and Fkbp1a 1 0.01 0.46 0
48 INT271994 Binding of Fkbp1a and Mtor 1 0.00 0.22 0
49 INT197815 Binding of MEN1 and TGFB1 1 0.16 0.13 0
50 INT351095 Binding of FKBP1A and RPS6KB1 1 0.24 0.36 0
51 INT351101 Negative_regulation of Binding of FKBP1A and RPS6KB1 1 0.27 0.36 0
52 INT197814 Binding of MEN1 and RELA 1 0.42 0.07 0
53 INT351096 Binding of FKBP1A and MTOR 1 0.28 1.35 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of activin receptor signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported in regulation of activin receptor signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT60575 Binding of Fkbp1a 9 0.26 2.09 4.46
2 INT120072 Gene_expression of Smad7 38 0.74 20.87 3.69
3 INT127111 Regulation of Inhba 5 0.60 2.85 3.28
4 INT127108 Gene_expression of Inhba 12 0.65 3.21 2.48
5 INT86147 Positive_regulation of Inhba 8 0.63 1.94 2.39
6 INT174924 Gene_expression of Smad7 6 0.41 3.59 1.76
7 INT174923 Positive_regulation of Gene_expression of Smad7 3 0.37 2.3 1.73
8 INT127110 Transcription of Inhba 3 0.58 1.44 1.59
9 INT120076 Positive_regulation of Gene_expression of Smad7 16 0.65 11.33 1.25
10 INT20764 Localization of INHBA 3 0.71 0.94 1.22
11 INT20762 Negative_regulation of Localization of INHBA 1 0.03 0 1.15
12 INT20763 Positive_regulation of Localization of INHBA 1 0.03 0 0.96
13 INT230251 Binding of FKBP1A 6 0.28 2.24 0.94
14 INT127109 Negative_regulation of Regulation of Inhba 1 0.38 0.5 0.88
15 INT20765 Negative_regulation of INHBA 6 0.34 1.91 0.77
16 INT272878 Negative_regulation of Smad7 4 0.41 3.86 0.72
17 INT197832 Localization of MEN1 1 0.80 11.01 0.63
18 INT296583 Gene_expression of Fgf10 3 0.59 2.64 0.57
19 INT296594 Regulation of Fgf10 1 0.15 1.53 0.56
20 INT127114 Regulation of Phosphorylation of Inhba 1 0.41 0.52 0.53
21 INT127107 Phosphorylation of Inhba 1 0.73 0.52 0.53
22 INT120074 Regulation of Gene_expression of Smad7 1 0.58 2.05 0.5
23 INT20766 Positive_regulation of INHBA 4 0.66 5.66 0.48
24 INT61102 Gene_expression of MEN1 12 0.78 17.7 0.43
25 INT224538 Negative_regulation of Gene_expression of Smad7 1 0.09 0.25 0.43
26 INT207064 Gene_expression of Fkbp1a 2 0.32 1.52 0.34
27 INT207065 Localization of Fkbp1a 1 0.36 0.82 0.33
28 INT184949 Positive_regulation of Gene_expression of Inhba 2 0.49 0.77 0.31
29 INT134840 Gene_expression of SMAD7 1 0.74 2.74 0.31
30 INT184716 Binding of Smad7 2 0.34 0.91 0.29
31 INT272890 Regulation of Negative_regulation of Smad7 1 0.19 1.33 0.29
32 INT190676 Binding of Fkbp1a 15 0.36 3.11 0.28
33 INT202802 Regulation of Fkbp1a 4 0.26 0.96 0.28
34 INT228793 Negative_regulation of Gene_expression of Smad7 5 0.25 2.33 0.23
35 INT349713 Positive_regulation of Transcription of Inhba 1 0.56 0.18 0.23
36 INT164519 Gene_expression of FKBP1A 2 0.39 0.22 0.19
37 INT228790 Positive_regulation of Smad7 4 0.41 0.58 0.15
38 INT293345 Negative_regulation of Binding of FKBP1A 1 0.02 0.19 0.13
39 INT305022 Positive_regulation of Transcription of INHBA 1 0.34 0.76 0.1
40 INT305023 Transcription of INHBA 1 0.47 0.75 0.1
41 INT222597 Localization of Inhba 1 0.08 0.07 0.09
42 INT184950 Negative_regulation of Inhba 1 0.41 0.74 0.09
43 INT299319 Localization of FKBP1A 1 0.44 0 0.09
44 INT144314 Gene_expression of INHBA 16 0.73 12.29 0.08
45 INT201554 Positive_regulation of Gene_expression of INHBA 3 0.47 2.9 0.08
46 INT353267 Negative_regulation of Positive_regulation of Smad7 1 0.25 0.32 0.08
47 INT222590 Regulation of Positive_regulation of Inhba 1 0.04 0 0.07
48 INT197836 Positive_regulation of Gene_expression of MEN1 1 0.50 3.16 0.07
49 INT197828 Negative_regulation of MEN1 1 0.43 5.06 0.06
50 INT347149 Localization of Smad7 1 0.67 0 0.05
51 INT299313 Positive_regulation of Gene_expression of FKBP1A 1 0.29 0 0.05
52 INT260760 Positive_regulation of Fgf10 2 0.53 0.43 0.03
53 INT303535 Positive_regulation of Gene_expression of Fgf10 1 0.53 0.34 0.03
54 INT350515 Transcription of SMAD7 1 0.07 0.38 0.03
55 INT353280 Phosphorylation of Smad7 1 0.48 0.06 0.03
56 INT347148 Regulation of Smad7 1 0.26 0 0
57 INT197841 Positive_regulation of MEN1 1 0.41 2.38 0
58 INT222623 Negative_regulation of Gene_expression of Inhba 1 0.06 0.08 0
59 INT218701 Negative_regulation of Binding of Smad7 1 0.14 0.15 0
60 INT166121 Binding of SMAD7 1 0.30 0.39 0
61 INT197843 Regulation of Localization of MEN1 1 0.45 0.24 0
62 INT353273 Negative_regulation of Phosphorylation of Smad7 1 0.25 0 0
63 INT197838 Transcription of MEN1 1 0.69 0.13 0
64 INT347145 Transcription of Smad7 1 0.68 0 0
65 INT222637 Regulation of Gene_expression of Inhba 1 0.06 0.06 0
66 INT222578 Positive_regulation of Localization of Inhba 1 0.05 0.07 0
67 INT197824 Positive_regulation of Transcription of MEN1 1 0.50 0.13 0
68 INT218685 Binding of Smad7 1 0.13 0.15 0
69 INT222642 Binding of Inhba 1 0.05 0 0
70 INT279773 Regulation of INHBA 1 0.26 0.65 0
71 INT197834 Binding of MEN1 1 0.48 3.32 0
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