GO:0032956

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Name regulation of actin cytoskeleton organization
Categary Process
Go Slim No
Go Link GO:0032956
Unique Molecular Interactions 321
Total Molecular Interactions 415
Total Single Events 2446
Pain Genes Associated 35

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of actin cytoskeleton organization. They are ordered first by their pain relevance and then by number of times they were reported for regulation of actin cytoskeleton organization. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT137918 Oprm1 Positive_regulation of Pdgfrb 1 0.41 0 3.31
2 INT108129 GDNF Regulation of Gene_expression of GRHL3 1 0.21 0.39 1.71
3 INT54601 Binding of Mtor and Ache 1 0.20 0.8 1.58
4 INT299311 Binding of RPTOR and RICTOR 1 0.38 0.21 1.4
5 INT95791 Binding of SSTR1 and GRHL3 1 0.38 0.57 0.99
6 INT108128 GDNF Regulation of Localization of GRHL3 1 0.24 0.18 0.83
7 INT316673 Binding of CALR and LRP1 1 0.39 1.89 0.74
8 INT45335 Mlst8 Positive_regulation of Localization of Abat 1 0.36 0 0.65
9 INT45334 Mlst8 Regulation of Localization of Abat 1 0.21 0 0.65
10 INT282286 Akt1 Positive_regulation of Pak1 1 0.15 0.24 0.61
11 INT334013 Ccl25 Positive_regulation of Gene_expression of Lrp1 1 0.07 0.98 0.56
12 INT146113 Binding of Adra2a and Lrp1 1 0.01 1.07 0.48
13 INT276207 Binding of Akt1 and Myo1f 1 0.11 0.05 0.47
14 INT197496 Binding of Apoe and Lrp1 4 0.22 2.32 0.46
15 INT147444 PDGFA Positive_regulation of Gene_expression of Ros1 2 0.00 0.95 0.46
16 INT273235 Binding of Cdk5 and Cdk5r1 1 0.24 6.06 0.46
17 INT273111 Bdnf Positive_regulation of Positive_regulation of Mtor 1 0.44 0.07 0.42
18 INT277353 VEGFA Regulation of Mtor 1 0.02 1.11 0.37
19 INT277354 Gene_expression of VEGFA Regulation of Mtor 1 0.02 1.1 0.37
20 INT316672 Binding of LRP1 and SFTPD 1 0.35 0.96 0.37
21 INT273118 Bdnf Positive_regulation of Mtor 1 0.66 0 0.33
22 INT339645 Binding of Cdk5r1 and Ebi3 1 0.01 0.78 0.31
23 INT150050 Mtor Positive_regulation of Rps6kb1 3 0.49 1.44 0.3
24 INT143688 Binding of Dlc1 and Trpv1 1 0.01 0.45 0.3
25 INT202313 Gene_expression of PDGFB Positive_regulation of Positive_regulation of Pdgfrb 1 0.14 1 0.29
26 INT298996 Il18 Positive_regulation of Gene_expression of Cdk5r1 1 0.03 1.65 0.29
27 INT202314 Gene_expression of PDGFB Positive_regulation of Phosphorylation of Pdgfrb 1 0.14 1 0.29
28 INT299011 Il18 Positive_regulation of Transcription of Cdk5r1 1 0.03 1.65 0.29
29 INT247949 Cdk5r1 Positive_regulation of Cdk5 1 0.26 1.12 0.28
30 INT75989 Regulation of RICTOR Positive_regulation of IK 1 0.00 0.15 0.27
31 INT75988 RICTOR Positive_regulation of IK 1 0.00 0.15 0.27
32 INT220635 Binding of Lrp1 and Kat5 2 0.09 0.71 0.25
33 INT198926 Binding of Apbb1 and Lrp1 5 0.12 2.18 0.24
34 INT177661 Binding of Trib3 and Myo1f 1 0.00 0.54 0.24
35 INT193031 CHRM2 Positive_regulation of ROCK1 1 0.00 0.12 0.24
36 INT273232 Negative_regulation of Binding of Cdk5 and Cdk5r1 1 0.28 3.16 0.23
37 INT193035 Positive_regulation of PDGFA Positive_regulation of EGF 1 0.05 0.53 0.21
38 INT326831 Cdk5r2 Positive_regulation of Binding of Cdk5r1 1 0.01 0.95 0.21
39 INT193025 PDGFA Positive_regulation of EGF 1 0.05 0.53 0.21
40 INT193036 EGF Positive_regulation of PDGFA 1 0.05 0.53 0.21
41 INT193032 Positive_regulation of EGF Positive_regulation of PDGFA 1 0.05 0.53 0.21
42 INT343547 ROCK1 Positive_regulation of Gene_expression of PTHLH 1 0.15 0.2 0.2
43 INT269446 Binding of EPHA3 and HHIP 1 0.01 0 0.2
44 INT221955 Binding of ELAVL1 and CDK5R1 1 0.01 0.93 0.19
45 INT221956 CDK5R1 Regulation of Positive_regulation of CDK5 1 0.21 0.62 0.19
46 INT192333 PDGFA Positive_regulation of Gene_expression of FN1 2 0.11 1.26 0.18
47 INT130932 Negative_regulation of Cpox Positive_regulation of Gene_expression of TSC1 1 0.00 0.42 0.18
48 INT193080 ROCK1 Positive_regulation of Ppp1r14a 1 0.00 0.13 0.18
49 INT164791 Cdk5r1 Positive_regulation of Cdk5 1 0.30 0.25 0.17
50 INT164790 Cdk5r1 Positive_regulation of Trib3 1 0.02 0.25 0.17
51 INT299001 Il18 Positive_regulation of Cdk5r1 1 0.03 0.36 0.17
52 INT349560 Olr779 Negative_regulation of Mtor 1 0.02 0.5 0.16
53 INT298717 Fgf2 Positive_regulation of Gene_expression of PDGFA 1 0.01 0.23 0.15
54 INT298716 Ngf Positive_regulation of Gene_expression of PDGFA 1 0.01 0.22 0.15
55 INT273902 Mtor Positive_regulation of Eif4ebp1 1 0.50 0.56 0.15
56 INT238331 PDGFA Regulation of Gene_expression of GOPC 1 0.04 0 0.14
57 INT349559 Mtor Regulation of Pdpk1 1 0.03 0.42 0.14
58 INT238330 Binding of PDGFA and Regulation of Gene_expression of GOPC 1 0.06 0 0.14
59 INT238333 Binding of PDGFA and Regulation of Gene_expression of ADAMTS1 1 0.06 0 0.14
60 INT286900 Binding of HBM and PDGFA 1 0.04 1.08 0.14
61 INT155687 PDGFA Positive_regulation of Phosphorylation of FBRS 1 0.01 0.43 0.14
62 INT273901 Mtor Positive_regulation of Eif4e 1 0.50 0.54 0.14
63 INT144027 Binding of Slc6a4 and Pdgfrb 1 0.23 0.25 0.14
64 INT238336 PDGFA Regulation of Negative_regulation of ADAMTS5 1 0.04 0 0.14
65 INT298715 Igf1 Positive_regulation of Gene_expression of PDGFA 1 0.00 0.22 0.14
66 INT252901 PTTG1 Regulation of Gene_expression of TSC1 1 0.00 1.61 0.13
67 INT261789 PDGFA Positive_regulation of Slc12a5 1 0.07 0.15 0.12
68 INT192330 UBR7 Negative_regulation of Positive_regulation of PDGFRB 1 0.01 0.54 0.12
69 INT343542 ROCK1 Positive_regulation of Positive_regulation of PTHLH 1 0.21 0 0.12
70 INT101231 Positive_regulation of Gria2 Positive_regulation of Binding of Mlst8 1 0.06 0 0.12
71 INT332687 Ros1 Positive_regulation of Crk 1 0.17 0.77 0.12
72 INT273103 Binding of Mtor and Rps6kb1 1 0.44 0 0.11
73 INT273112 Positive_regulation of Binding of Mtor and Rps6kb1 1 0.46 0.05 0.11
74 INT221958 CDK5R1 Positive_regulation of Positive_regulation of CDK5 1 0.36 0.38 0.1
75 INT313482 Binding of MTOR and SST 1 0.01 0 0.1
76 INT42067 Rln1 Positive_regulation of Phosphorylation of Myo1f 1 0.11 0.1 0.1
77 INT215245 Binding of Myo1f and Chd7 1 0.00 0.64 0.1
78 INT221959 Binding of CDK5 and CDK5R1 1 0.28 0.53 0.1
79 INT201748 Car2 Positive_regulation of Cdk5r1 1 0.00 0.67 0.09
80 INT74014 Binding of TSC1 and XRCC1 1 0.02 1.98 0.09
81 INT276304 PRDM1 Regulation of TSC1 1 0.01 1.29 0.09
82 INT276391 Prdm1 Regulation of TSC1 1 0.00 1.29 0.09
83 INT347302 PDGFA Positive_regulation of ITK 1 0.04 1.4 0.09
84 INT308666 Binding of Lrp1 and Chol1 1 0.10 0.69 0.09
85 INT20959 Binding of PTPRC and Pak1 1 0.01 0.76 0.09
86 INT221258 Negative_regulation of Binding of VDAC1 and Crk 1 0.00 0.22 0.08
87 INT272012 Binding of TSC1 and Lsamp 1 0.03 2.1 0.08
88 INT249126 Binding of Ephb1 and Mtor 1 0.02 0 0.08
89 INT20957 Binding of Pak1 and Pak2 1 0.27 0.65 0.08
90 INT251777 Negative_regulation of TXK Positive_regulation of PDGFA 1 0.04 1 0.08
91 INT244639 AGK Negative_regulation of PDGFRB 1 0.01 0.69 0.08
92 INT273104 Mtor Negative_regulation of Gene_expression of Gria1 1 0.46 0.15 0.08
93 INT251773 TXK Positive_regulation of PDGFA 1 0.04 1 0.08
94 INT221255 Binding of VDAC1 and Crk 1 0.00 0.22 0.08
95 INT308655 Binding of Lrp1 and Gopc 1 0.01 0.49 0.07
96 INT88411 Positive_regulation of PDGFA Positive_regulation of CDK2 1 0.11 0 0.07
97 INT231440 PDGFA Positive_regulation of Gene_expression of HGF 1 0.16 0.83 0.07
98 INT273107 Bdnf Regulation of Positive_regulation of Mtor 1 0.26 0.09 0.07
99 INT231434 FN1 Positive_regulation of Gene_expression of PDGFA 1 0.04 0.83 0.07
100 INT298006 CHDM Positive_regulation of Gene_expression of PDGFRB 1 0.16 1.08 0.07
101 INT192329 UBR7 Negative_regulation of Phosphorylation of PDGFRB 1 0.01 0.06 0.07
102 INT247948 Positive_regulation of Cdk5r1 Positive_regulation of Cdk5 1 0.26 0.16 0.07
103 INT272003 Binding of Tsc2 and Tsc1 1 0.18 1.1 0.07
104 INT42066 Rln1 Regulation of Phosphorylation of Myo1f 1 0.05 0.07 0.07
105 INT246539 EGF Negative_regulation of Gene_expression of PDGFA 1 0.06 0.38 0.07
106 INT88408 PDGFA Positive_regulation of CDK2 1 0.11 0 0.07
107 INT246538 PDGFA Negative_regulation of Gene_expression of EGF 1 0.06 0.38 0.07
108 INT231441 PDGFA Positive_regulation of Gene_expression of VEGFA 1 0.17 0.83 0.07
109 INT267000 Mdk Negative_regulation of Positive_regulation of Baiap2 1 0.03 0.1 0.06
110 INT279280 Binding of PDGFA and PDGFB 1 0.06 0.9 0.06
111 INT279291 PDGFA Positive_regulation of PDGFRB 1 0.16 1.02 0.06
112 INT279275 PDGFA Positive_regulation of TXK 1 0.05 1.02 0.06
113 INT279276 PDGFA Positive_regulation of NCOR2 1 0.00 1.02 0.06
114 INT267040 Negative_regulation of NOS1 Negative_regulation of Positive_regulation of Baiap2 1 0.02 0.1 0.06
115 INT273098 Binding of Bdnf and Positive_regulation of Mtor 1 0.47 0 0.06
116 INT244641 PDGFA Regulation of MTOR 1 0.07 2.55 0.06
117 INT279287 PDGFRB Regulation of CDCP1 1 0.01 0.98 0.05
118 INT273096 Mtor Positive_regulation of Gene_expression of Grip2 1 0.05 0.07 0.05
119 INT329216 Prkag1 Regulation of Mtor 1 0.01 0.35 0.04
120 INT253376 Lep Regulation of Mtor 1 0.17 0.08 0.04
121 INT202310 Binding of PDGFB and Pdgfrb 1 0.11 0.39 0.04
122 INT246793 Binding of Tsc2 and Tsc1 1 0.04 0.71 0.04
123 INT292092 Binding of PDGFRB and TXK 1 0.05 1.53 0.04
124 INT221952 UTS2R Regulation of Protein_catabolism of CDK5R1 1 0.10 0.3 0.04
125 INT215240 Binding of Myo1f and Racgap1 1 0.01 0.77 0.04
126 INT311730 Binding of Plat and Lrp1 1 0.14 0.65 0.04
127 INT223086 Binding of Pdgfb and Pdgfrb 1 0.33 0.46 0.04
128 INT326830 Cdk5r1 Positive_regulation of Positive_regulation of Cdk5 1 0.09 0.16 0.04
129 INT257874 Agt Positive_regulation of Mtor 1 0.04 0.37 0.04
130 INT221953 UTS2R Positive_regulation of Gene_expression of CDK5R1 1 0.16 0.23 0.04
131 INT257881 Ins1 Positive_regulation of Mtor 1 0.05 0.37 0.04
132 INT292079 Negative_regulation of Binding of PDGFRB and TXK 1 0.06 1.54 0.04
133 INT198919 Binding of Lrp1 and Lrpap1 1 0.07 0 0.04
134 INT198921 Binding of App and Lrp1 3 0.32 2.7 0.03
135 INT302159 TSC1 Positive_regulation of Transcription of CDKN1A 1 0.00 0.28 0.03
136 INT269584 Binding of CFL1 and ROCK1 1 0.03 0.05 0.03
137 INT336752 Sparc Regulation of Regulation of Ilk 1 0.30 0.71 0.03
138 INT356102 Negative_regulation of Binding of App and Lrp1 1 0.32 0.71 0.03
139 INT343546 Negative_regulation of ROCK1 Negative_regulation of Gene_expression of PTHLH 1 0.16 3.28 0.03
140 INT343545 Binding of GLI2 and ROCK1 1 0.07 0.65 0.03
141 INT332286 PIK3CD Positive_regulation of MTOR 1 0.14 0.73 0.03
142 INT221962 UTS2R Regulation of Gene_expression of CDK5R1 1 0.09 0.43 0.03
143 INT298878 Binding of MTOR and RAB7A 1 0.07 0.35 0.03
144 INT272009 Binding of YWHAQ and Tsc1 1 0.37 0.14 0.03
145 INT256549 Binding of Pten and Mtor 1 0.00 1.02 0.03
146 INT272596 Binding of Dlg4 and Lrp1 1 0.16 0 0.03
147 INT221963 ELAVL1 Regulation of Gene_expression of CDK5R1 1 0.01 0.58 0.03
148 INT343537 ROCK1 Regulation of Gene_expression of PTHLH 1 0.08 0.09 0.03
149 INT341537 F2RL1 Positive_regulation of TSC1 1 0.01 0.76 0.03
150 INT313485 MTOR Positive_regulation of Gene_expression of P2RX1 1 0.16 0 0.03
151 INT273105 Mtor Regulation of Gria1 1 0.29 0.07 0.03
152 INT279277 PDGFB Positive_regulation of PDGFRB 1 0.14 0.52 0.03
153 INT220636 Binding of Lrp1 and Bace1 2 0.32 0.62 0
154 INT209984 Binding of LDLR and LRP1 1 0.08 0 0
155 INT198009 MTOR Regulation of HCC 1 0.09 1.1 0
156 INT303406 Binding of NPAT and Myo1f 1 0.06 0 0
157 INT253359 Positive_regulation of Prkaa2 Negative_regulation of Mtor 1 0.26 0.27 0
158 INT292137 Regulation of Mtor Regulation of Gene_expression of VEGFA 1 0.01 0.75 0
159 INT347304 PDGFA Positive_regulation of Gene_expression of AKT1 1 0.19 0.6 0
160 INT150051 Mtor Positive_regulation of Eif4ebp1 1 0.50 0.46 0
161 INT198024 CDCP1 Negative_regulation of MTOR 1 0.00 0.97 0
162 INT251780 RRAD Negative_regulation of MTOR 1 0.00 0.62 0
163 INT356108 App Positive_regulation of Positive_regulation of Lrp1 1 0.43 0.52 0
164 INT352995 IPMK Regulation of PDGFA 1 0.00 0.66 0
165 INT246808 Tsc2 Regulation of Regulation of Tsc1 1 0.02 0.05 0
166 INT273106 Binding of Mtor and Cby1 1 0.01 0 0
167 INT303331 Mtor Positive_regulation of Rps6kb1 1 0.07 0.07 0
168 INT273116 Binding of Fkbp1a and Mtor 1 0.37 0 0
169 INT296960 Binding of NRIP1 and MLST8 1 0.03 2.65 0
170 INT258209 ROCK1 Regulation of ARR3 1 0.00 0.2 0
171 INT223575 AKT1 Regulation of MTOR 1 0.12 0.37 0
172 INT276887 MTOR Regulation of Ppargc1a 1 0.23 0.33 0
173 INT250668 AKT1 Positive_regulation of MTOR 1 0.16 1.26 0
174 INT271990 Tsc1 Positive_regulation of Tsc2 1 0.36 0.31 0
175 INT315868 Vhl Positive_regulation of Transcription of PDGFA 1 0.00 1.39 0
176 INT347124 Binding of FZD1 and Lrp1 1 0.11 0.24 0
177 INT272018 Binding of TSC1 and Tsc2 1 0.17 0.48 0
178 INT331222 Tsc1 Negative_regulation of Mtor 1 0.00 0.68 0
179 INT271996 Binding of Plk1 and Tsc1 1 0.09 0.32 0
180 INT258202 ROCK1 Positive_regulation of MYL2 1 0.14 0.2 0
181 INT292136 Mtor Regulation of Gene_expression of VEGFA 1 0.01 0.75 0
182 INT331235 RASA1 Positive_regulation of Mtor 1 0.00 0.32 0
183 INT297614 ZNF275 Positive_regulation of Gene_expression of TSC1 1 0.00 1.56 0
184 INT356095 Lrp1 Positive_regulation of App 1 0.37 0.53 0
185 INT356091 Lrp1 Positive_regulation of Positive_regulation of App 1 0.43 0.52 0
186 INT192328 UBR7 Regulation of Phosphorylation of PDGFA 1 0.00 0 0
187 INT250663 Phosphorylation of AKT1 Positive_regulation of MTOR 1 0.16 1.26 0
188 INT271991 Tsc1 Regulation of Tsc2 1 0.23 0.15 0
189 INT321772 Binding of Myo7a and Twf2 1 0.00 0 0
190 INT272015 Pkd1 Positive_regulation of Localization of TSC1 1 0.18 0.65 0
191 INT299306 Binding of QPCT and RICTOR 1 0.02 0 0
192 INT223582 Negative_regulation of MTOR Positive_regulation of Phosphorylation of ESR1 1 0.31 0.67 0
193 INT262759 PIK3CG Positive_regulation of MTOR 1 0.38 0.54 0
194 INT272017 TBC1D7 Positive_regulation of Protein_catabolism of Tsc1 1 0.08 0.46 0
195 INT225873 Ilk Positive_regulation of AKT1 1 0.00 0.07 0
196 INT297613 Negative_regulation of ZNF275 Positive_regulation of Gene_expression of TSC1 1 0.00 1.66 0
197 INT198007 MTOR Regulation of Gene_expression of GOPC 1 0.08 1.33 0
198 INT259093 Binding of TSC1 and LMO4 1 0.02 0.74 0
199 INT225876 PIK3CG Positive_regulation of Ilk 1 0.00 0 0
200 INT217786 TSC1 Regulation of MITF 1 0.00 1.27 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of actin cytoskeleton organization. They are ordered first by their pain relevance and then by number of times they were reported in regulation of actin cytoskeleton organization. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT15305 Positive_regulation of Mtor 51 0.67 8.28 11
2 INT20166 Negative_regulation of Mtor 32 0.56 10.64 10.25
3 INT95794 Gene_expression of GRHL3 9 0.68 5.57 9.9
4 INT15307 Regulation of Mtor 27 0.48 4.7 9.34
5 INT127961 Transcription of GRHL3 1 0.45 4.34 8.17
6 INT53487 Gene_expression of TSC1 81 0.58 77.71 7.94
7 INT95117 Gene_expression of PDGFA 71 0.71 51.17 6.9
8 INT60161 Gene_expression of EPHA3 43 0.75 3.66 6.25
9 INT134468 Gene_expression of Cdk5r1 26 0.48 27.09 5.2
10 INT24080 Negative_regulation of Mtor 64 0.37 41.56 5.19
11 INT23611 Gene_expression of Mtor 23 0.66 3.57 5.02
12 INT127964 Regulation of Transcription of GRHL3 1 0.28 2.54 4.84
13 INT109219 Negative_regulation of Cdk5r1 5 0.43 1.22 4.25
14 INT127962 Positive_regulation of GRHL3 3 0.32 2.67 3.69
15 INT73463 Positive_regulation of Gene_expression of TSC1 20 0.38 14.59 3.53
16 INT127963 Positive_regulation of Gene_expression of GRHL3 1 0.44 1.85 3.4
17 INT22375 Localization of PDGFA 21 0.75 15.46 3.25
18 INT91173 Gene_expression of Pdgfrb 33 0.65 32.55 3.09
19 INT115348 Localization of Baiap2 1 0.68 1.76 2.99
20 INT41721 Negative_regulation of MTOR 40 0.58 32.49 2.83
21 INT228678 Phosphorylation of Mtor 15 0.78 3.18 2.76
22 INT201632 Positive_regulation of Cdk5r1 20 0.40 21.6 2.75
23 INT269377 Positive_regulation of EPHA3 22 0.18 0.97 2.55
24 INT15540 Positive_regulation of PDGFA 24 0.47 19.01 2.5
25 INT137908 Phosphorylation of Pdgfrb 14 0.81 8.44 2.45
26 INT101603 Positive_regulation of Cdk5r1 4 0.56 1.12 2.35
27 INT42140 Gene_expression of Myo1f 7 0.19 2.45 2.27
28 INT163545 Gene_expression of PDGFRB 39 0.78 25.5 2.2
29 INT108131 Localization of GRHL3 3 0.73 1.03 2.18
30 INT55470 Regulation of Mtor 16 0.24 12.51 2.07
31 INT93764 Binding of GRHL3 3 0.36 1.79 2.07
32 INT36293 Gene_expression of Mtor 24 0.25 14.5 2.04
33 INT12965 Negative_regulation of RICTOR 3 0.37 0.32 2
34 INT137906 Positive_regulation of Phosphorylation of Pdgfrb 6 0.50 2.55 1.94
35 INT144020 Positive_regulation of Pdgfrb 30 0.69 24.8 1.92
36 INT198885 Gene_expression of Lrp1 33 0.57 10.2 1.91
37 INT24850 Regulation of GRHL3 4 0.45 0.32 1.9
38 INT56925 Negative_regulation of TSC1 54 0.52 63.39 1.87
39 INT42065 Phosphorylation of Myo1f 13 0.38 2.05 1.71
40 INT101599 Gene_expression of Cdk5r1 5 0.63 1.27 1.68
41 INT2498 Positive_regulation of Mlst8 2 0.47 0.73 1.56
42 INT26579 Regulation of RICTOR 2 0.23 0.09 1.51
43 INT101601 Regulation of Cdk5r1 3 0.50 1.2 1.46
44 INT41719 Gene_expression of MTOR 27 0.77 19.43 1.44
45 INT166764 Localization of Mtor 2 0.75 1.28 1.42
46 INT115350 Positive_regulation of Localization of Baiap2 1 0.45 0.76 1.36
47 INT214073 Binding of TSC1 9 0.37 22 1.34
48 INT114969 Gene_expression of CDK5R1 3 0.75 11.24 1.33
49 INT168312 Positive_regulation of Gene_expression of EPHA3 8 0.49 0.97 1.32
50 INT95116 Negative_regulation of PDGFA 24 0.57 19.56 1.29
51 INT144019 Negative_regulation of Pdgfrb 21 0.58 14.93 1.26
52 INT228671 Negative_regulation of Phosphorylation of Mtor 8 0.50 1.77 1.2
53 INT98595 Regulation of ILK 6 0.62 3.84 1.16
54 INT138783 Positive_regulation of Gene_expression of Cdk5r1 2 0.38 0.68 1.15
55 INT93765 Negative_regulation of Binding of GRHL3 1 0.41 0.43 1.14
56 INT126534 Negative_regulation of ROCK1 18 0.49 14.32 1.13
57 INT210392 Regulation of PDGFA 10 0.36 11.41 1.12
58 INT203890 Positive_regulation of Gene_expression of Cdk5r1 9 0.40 9.13 1.11
59 INT42138 Binding of Myo1f 5 0.10 1.49 1.03
60 INT151774 Positive_regulation of Mtor 38 0.45 20.15 1.01
61 INT198904 Localization of Lrp1 11 0.62 3.25 1.01
62 INT73465 Transcription of TSC1 4 0.07 3.47 0.96
63 INT109221 Positive_regulation of Negative_regulation of Cdk5r1 1 0.37 0.15 0.95
64 INT188317 Positive_regulation of Gene_expression of PDGFA 15 0.46 12.7 0.91
65 INT198872 Binding of Lrp1 9 0.36 2.73 0.89
66 INT167424 Positive_regulation of Pak1 1 0.14 1.43 0.83
67 INT269642 Binding of EPHA3 4 0.10 0.22 0.8
68 INT74019 Regulation of TSC1 27 0.35 23.61 0.79
69 INT171096 Transcription of PDGFA 5 0.47 4.42 0.79
70 INT77663 Positive_regulation of CDK5R1 3 0.67 0.43 0.79
71 INT271917 Phosphorylation of Mtor 11 0.13 6.76 0.78
72 INT95118 Negative_regulation of Gene_expression of PDGFA 4 0.54 5.03 0.76
73 INT273220 Positive_regulation of Positive_regulation of Cdk5r1 4 0.40 5.3 0.75
74 INT296992 Gene_expression of MLST8 19 0.07 18.39 0.73
75 INT164756 Negative_regulation of PDGFRB 32 0.57 21.69 0.72
76 INT276176 Negative_regulation of Myo1f 4 0.12 1.85 0.71
77 INT60503 Positive_regulation of RICTOR 4 0.36 0.14 0.71
78 INT213923 Positive_regulation of MTOR 16 0.65 9.28 0.7
79 INT171364 Localization of Pdgfrb 6 0.37 4.98 0.68
80 INT91172 Positive_regulation of Gene_expression of Pdgfrb 4 0.38 2.83 0.68
81 INT122061 Negative_regulation of Lrp1 5 0.30 2.47 0.66
82 INT171380 Positive_regulation of Localization of Pdgfrb 1 0.21 0.48 0.66
83 INT15303 Transcription of Mtor 1 0.47 0.17 0.66
84 INT15302 Regulation of Transcription of Mtor 1 0.31 0.17 0.66
85 INT134472 Binding of Cdk5r1 4 0.26 4.25 0.65
86 INT210390 Binding of PDGFA 12 0.36 6.78 0.63
87 INT77662 Regulation of CDK5R1 2 0.60 1.93 0.63
88 INT115347 Regulation of Localization of Baiap2 1 0.23 0.38 0.62
89 INT221978 Regulation of Gene_expression of CDK5R1 1 0.59 5.08 0.61
90 INT163857 Gene_expression of Dlc1 1 0.03 0.17 0.6
91 INT98590 Negative_regulation of Positive_regulation of ILK 1 0.43 1.17 0.55
92 INT98592 Gene_expression of ILK 6 0.78 5.23 0.53
93 INT164196 Binding of LRP1 5 0.47 2.59 0.53
94 INT273230 Negative_regulation of Cdk5r1 1 0.25 4.48 0.53
95 INT45333 Localization of Mlst8 1 0.63 0 0.52
96 INT144024 Negative_regulation of Phosphorylation of Pdgfrb 6 0.42 3.48 0.51
97 INT161248 Positive_regulation of Gene_expression of Mtor 2 0.06 6.47 0.51
98 INT198048 Protein_catabolism of PDGFA 2 0.28 2.05 0.5
99 INT343801 Negative_regulation of Transcription of PDGFA 1 0.29 0.37 0.5
100 INT223599 Regulation of MTOR 14 0.42 8.52 0.49
101 INT42139 Regulation of Myo1f 3 0.14 0.64 0.49
102 INT98594 Positive_regulation of ILK 3 0.70 1.74 0.49
103 INT73200 Positive_regulation of PDGFRB 10 0.67 9.67 0.48
104 INT45338 Gene_expression of RICTOR 4 0.52 0.89 0.48
105 INT271939 Regulation of Tsc1 2 0.41 1.16 0.47
106 INT276175 Positive_regulation of Transcription of Myo1f 1 0.10 1.03 0.47
107 INT276194 Positive_regulation of Gene_expression of Myo1f 1 0.14 1.03 0.47
108 INT253391 Positive_regulation of Positive_regulation of Mtor 7 0.48 0.39 0.46
109 INT276190 Transcription of Myo1f 1 0.11 1.02 0.46
110 INT276191 Negative_regulation of Binding of Myo1f 1 0.09 0.05 0.46
111 INT175423 Positive_regulation of TSC1 25 0.36 21.81 0.45
112 INT198906 Positive_regulation of Localization of Lrp1 4 0.53 0.51 0.45
113 INT201636 Protein_catabolism of Cdk5r1 3 0.18 2.79 0.44
114 INT230517 Localization of Myo1f 2 0.15 1.38 0.44
115 INT45845 Negative_regulation of Gene_expression of Mlst8 1 0.43 0 0.44
116 INT192342 Phosphorylation of PDGFRB 11 0.80 1.68 0.43
117 INT269613 Negative_regulation of Binding of EPHA3 2 0.11 0.27 0.43
118 INT45331 Regulation of Mlst8 1 0.40 0 0.43
119 INT326821 Positive_regulation of Protein_catabolism of Cdk5r1 1 0.13 1.9 0.41
120 INT35501 Positive_regulation of Myo1f 5 0.69 1.73 0.39
121 INT136180 Binding of MTOR 9 0.35 5.01 0.38
122 INT192344 Negative_regulation of Phosphorylation of PDGFRB 4 0.54 1.26 0.38
123 INT16932 Localization of EPHA3 3 0.73 0.15 0.38
124 INT126389 Binding of RICTOR 1 0.01 0.08 0.38
125 INT228668 Positive_regulation of Localization of Mtor 1 0.39 0.62 0.38
126 INT126390 Positive_regulation of Binding of RICTOR 1 0.01 0.08 0.38
127 INT156201 Negative_regulation of Gene_expression of MTOR 6 0.58 7.7 0.36
128 INT181575 Phosphorylation of Crk 1 0.61 1.78 0.36
129 INT66251 Negative_regulation of Phosphorylation of Myo1f 1 0.20 0 0.35
130 INT146107 Positive_regulation of Lrp1 4 0.37 1.91 0.34
131 INT143687 Positive_regulation of Dlc1 1 0.01 0.46 0.34
132 INT181580 Gene_expression of Crk 1 0.75 1.2 0.33
133 INT198889 Protein_catabolism of Lrp1 5 0.68 1.6 0.32
134 INT184803 Localization of TSC1 5 0.37 6.13 0.32
135 INT274626 Positive_regulation of Positive_regulation of GRHL3 1 0.22 0.67 0.32
136 INT342668 Regulation of LRP1 1 0.01 0.2 0.31
137 INT249123 Binding of Mtor 9 0.36 0.57 0.3
138 INT127984 Positive_regulation of LRP1 5 0.69 0.74 0.3
139 INT192348 Positive_regulation of Gene_expression of PDGFRB 5 0.64 3.57 0.3
140 INT256540 Regulation of Gene_expression of TSC1 4 0.07 4.74 0.3
141 INT247937 Localization of Cdk5r1 3 0.41 1.21 0.3
142 INT192346 Positive_regulation of Localization of PDGFA 5 0.37 1.52 0.29
143 INT185436 Gene_expression of ROCK1 5 0.52 6.85 0.29
144 INT144021 Binding of Pdgfrb 9 0.37 5.53 0.28
145 INT41720 Positive_regulation of Gene_expression of MTOR 2 0.49 1.54 0.28
146 INT41722 Positive_regulation of Negative_regulation of MTOR 1 0.45 0.73 0.28
147 INT98593 Positive_regulation of Positive_regulation of ILK 1 0.50 0.58 0.28
148 INT298974 Transcription of Cdk5r1 1 0.04 1.64 0.28
149 INT298809 Localization of MLST8 2 0.07 2.17 0.26
150 INT322756 Negative_regulation of Tsc1 1 0.07 1.4 0.26
151 INT156207 Negative_regulation of Phosphorylation of MTOR 5 0.58 2.33 0.25
152 INT223078 Negative_regulation of Gene_expression of Pdgfrb 4 0.35 3.64 0.25
153 INT273216 Negative_regulation of Gene_expression of Cdk5r1 1 0.25 1.73 0.25
154 INT279296 Localization of PDGFRB 4 0.54 2.71 0.24
155 INT198873 Regulation of Lrp1 3 0.35 1.45 0.24
156 INT98597 Positive_regulation of Gene_expression of ILK 4 0.70 3.08 0.23
157 INT327033 Negative_regulation of Phosphorylation of Mtor 3 0.07 1.38 0.23
158 INT22405 Positive_regulation of Crk 2 0.09 0.64 0.23
159 INT276203 Negative_regulation of Gene_expression of Myo1f 1 0.09 0.38 0.23
160 INT258250 Positive_regulation of ROCK1 7 0.51 2.07 0.22
161 INT45844 Gene_expression of Mlst8 2 0.67 0.09 0.22
162 INT156204 Phosphorylation of MTOR 15 0.82 3.99 0.21
163 INT195576 Binding of Myo1f 6 0.06 2.79 0.21
164 INT217832 Negative_regulation of Gene_expression of TSC1 5 0.04 5.45 0.21
165 INT185443 Regulation of ROCK1 4 0.18 3.32 0.21
166 INT282732 Positive_regulation of Phosphorylation of Mtor 4 0.06 2.09 0.2
167 INT326823 Positive_regulation of Localization of Cdk5r1 1 0.09 0.9 0.2
168 INT267833 Phosphorylation of MLST8 1 0.01 1.68 0.2
169 INT349553 Negative_regulation of Negative_regulation of Mtor 1 0.40 0.67 0.19
170 INT257861 Positive_regulation of Gene_expression of Mtor 5 0.48 0.9 0.18
171 INT296978 Negative_regulation of MLST8 3 0.04 5.26 0.18
172 INT332297 Negative_regulation of Binding of MTOR 2 0.40 1.6 0.18
173 INT134469 Positive_regulation of Binding of Cdk5r1 1 0.35 0.4 0.18
174 INT98591 Positive_regulation of Regulation of ILK 1 0.47 0.7 0.18
175 INT198877 Regulation of Gene_expression of Lrp1 2 0.32 0.62 0.17
176 INT38976 Positive_regulation of Negative_regulation of Mtor 2 0.48 0 0.17
177 INT23890 Binding of CDK5R1 2 0.36 0.23 0.16
178 INT127985 Localization of LRP1 1 0.80 0.21 0.16
179 INT343138 Gene_expression of Mlst8 1 0.03 0 0.15
180 INT249124 Regulation of Regulation of Mtor 1 0.11 0 0.15
181 INT192339 Positive_regulation of Positive_regulation of PDGFRB 2 0.46 1.02 0.14
182 INT298811 Transcription of MLST8 1 0.06 0.77 0.14
183 INT298818 Negative_regulation of Transcription of MLST8 1 0.04 0.78 0.14
184 INT276193 Regulation of Negative_regulation of Myo1f 1 0.09 0.38 0.14
185 INT155694 Phosphorylation of PDGFA 2 0.58 0.42 0.13
186 INT296990 Positive_regulation of MLST8 2 0.05 2.89 0.13
187 INT296995 Regulation of MLST8 2 0.03 3.1 0.13
188 INT253392 Positive_regulation of Phosphorylation of Mtor 2 0.42 0.26 0.13
189 INT144023 Negative_regulation of Positive_regulation of Pdgfrb 2 0.42 1.43 0.13
190 INT210396 Negative_regulation of Binding of PDGFA 1 0.02 1.6 0.13
191 INT221969 Negative_regulation of CDK5R1 1 0.41 0.44 0.13
192 INT278037 Positive_regulation of Transcription of PDGFA 4 0.07 2.39 0.12
193 INT269628 Regulation of EPHA3 2 0.12 0.2 0.12
194 INT101227 Positive_regulation of Binding of Mlst8 1 0.07 0 0.12
195 INT101228 Binding of Mlst8 1 0.07 0 0.12
196 INT277350 Negative_regulation of Localization of Mtor 1 0.03 1.39 0.11
197 INT257855 Regulation of Positive_regulation of Mtor 3 0.35 0.54 0.1
198 INT338914 Negative_regulation of Phosphorylation of CRK 1 0.08 0 0.1
199 INT101600 Regulation of Gene_expression of Cdk5r1 1 0.50 0.16 0.1
200 INT267034 Gene_expression of Baiap2 1 0.24 0.15 0.1
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