GO:0033017

From wiki-pain
Jump to: navigation, search
Name sarcoplasmic reticulum membrane
Categary Component
Go Slim No
Go Link GO:0033017
Unique Molecular Interactions 82
Total Molecular Interactions 102
Total Single Events 856
Pain Genes Associated 19

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for sarcoplasmic reticulum membrane. They are ordered first by their pain relevance and then by number of times they were reported for sarcoplasmic reticulum membrane. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT144454 Binding of DMPK and GPM6A 1 0.00 0 1.45
2 INT168866 Binding of RYR1 and Cd38 1 0.02 0.17 1.28
3 INT228680 Fkbp1a Negative_regulation of Trib3 1 0.01 0.56 1.18
4 INT116803 Phosphorylation of Camk2b Positive_regulation of Camk4 1 0.03 0 0.76
5 INT116805 Phosphorylation of Camk2b Positive_regulation of Camk2a 1 0.07 0 0.76
6 INT216941 P2rx7 Regulation of Ryr1 1 0.01 0.55 0.52
7 INT137834 Binding of CAMK2B and CTS 1 0.05 1.38 0.42
8 INT149221 Binding of Ryr1 and Trpc3 5 0.40 0 0.37
9 INT118852 Positive_regulation of GNA14 Positive_regulation of CAMK2G 1 0.01 0.09 0.27
10 INT118846 GNA14 Positive_regulation of CAMK2G 1 0.01 0.09 0.27
11 INT311533 ROS1 Positive_regulation of Positive_regulation of RYR3 1 0.28 0.18 0.26
12 INT107189 Atp2a2 Negative_regulation of Atp2a1 1 0.27 0 0.26
13 INT311532 ROS1 Regulation of RYR3 1 0.43 0.18 0.25
14 INT283373 Pcbd1 Regulation of RYR1 1 0.00 1.45 0.21
15 INT315032 Binding of Cav1 and Ryr1 1 0.27 0.2 0.14
16 INT207785 Binding of RYR1 and Ap3d1 1 0.06 3.24 0.13
17 INT207776 Binding of FKBP1A and RYR1 1 0.05 0.59 0.12
18 INT351427 Binding of PIK3C3 and RYR1 1 0.00 0 0.11
19 INT149219 Binding of Ryr1 and Trpc1 1 0.35 0 0.11
20 INT225740 RYR1 Positive_regulation of Binding of Entpd1 1 0.08 0.08 0.1
21 INT349340 SRI Regulation of Rpe 1 0.02 0.05 0.09
22 INT147673 SRI Positive_regulation of Per1 1 0.03 0 0.09
23 INT147661 Binding of GRP and SRI 1 0.00 0 0.08
24 INT221477 Gadd45b Negative_regulation of SRI 1 0.03 0.27 0.08
25 INT265983 Homer1 Regulation of Ryr1 1 0.37 0.15 0.07
26 INT170517 Binding of Ryr1 and Qdpr 2 0.15 0.36 0.05
27 INT285184 Negative_regulation of Atp2a2 Negative_regulation of Localization of Ca2 1 0.04 0.66 0.05
28 INT293360 Binding of CSH1 and FKBP1A 1 0.00 0.14 0.05
29 INT207760 Fkbp1a Regulation of MSMB 1 0.12 0.69 0.04
30 INT179903 Binding of ELANE and SRI 1 0.17 1.07 0.03
31 INT293358 Binding of FKBP1A and CABIN1 1 0.00 0.07 0.03
32 INT255146 Negative_regulation of Binding of Dmpk and Hnrnph1 1 0.11 0 0
33 INT311298 Binding of DMPK and Mbnl1 1 0.43 0.54 0
34 INT192046 Negative_regulation of Binding of RYR2 and Cbx5 1 0.01 1.12 0
35 INT265231 Binding of FKBP1A and TGFBR1 1 0.11 0.35 0
36 INT249200 ATP2A2 Negative_regulation of CA2 1 0.01 0 0
37 INT66344 ANTXR1 Positive_regulation of ART1 1 0.00 0.69 0
38 INT293355 Binding of Fkbp1a and CABIN1 1 0.00 0.12 0
39 INT272523 Binding of DMPK and Gtf3a 1 0.00 0.81 0
40 INT273116 Binding of Fkbp1a and Mtor 1 0.37 0 0
41 INT273289 Binding of Psen2 and Ryr2 1 0.27 4.53 0
42 INT266704 Binding of RYR1 and TRDN 1 0.34 0 0
43 INT316647 Ryr1 Regulation of Qdpr 1 0.19 0.68 0
44 INT192049 Negative_regulation of Binding of RYR2 and Cbx1 1 0.01 1.12 0
45 INT255144 Binding of Dmpk and Hnrnph1 1 0.09 0 0
46 INT221910 Binding of SRI and COPD 1 0.01 1.27 0
47 INT192045 Jup Positive_regulation of RYR2 1 0.11 0.29 0
48 INT255147 Binding of Dmpk and Mbnl1 1 0.34 0 0
49 INT283372 Binding of RYR1 and Pcbd1 1 0.00 0.28 0
50 INT309746 CALM3 Positive_regulation of CAMK2G 1 0.02 0 0
51 INT293354 Binding of CSH1 and Fkbp1a 1 0.00 0.12 0
52 INT265233 Binding of APC and FKBP1A 1 0.08 0.41 0
53 INT179905 Positive_regulation of ELANE Positive_regulation of SRI 1 0.19 0.92 0
54 INT265234 Binding of FKBP1A and SGCG 1 0.03 0.35 0
55 INT293366 Binding of CABIN1 and Fkbp1a 1 0.00 0.05 0
56 INT272520 Gene_expression of Dmpk Positive_regulation of Positive_regulation of Nkx2-5 1 0.02 0.43 0
57 INT265232 Regulation of Binding of APC and FKBP1A 1 0.08 0.41 0
58 INT192047 Binding of RYR2 and Cbx1 1 0.01 1.12 0
59 INT271999 Binding of Fkbp1a and Positive_regulation of Negative_regulation of Mtor 1 0.00 0.18 0
60 INT192043 Binding of RYR2 and Cbx5 1 0.01 1.12 0
61 INT272524 DICER1 Negative_regulation of Dmpk 1 0.04 0.07 0
62 INT190681 Binding of Bcl2 and Fkbp1a 1 0.01 0.46 0
63 INT271994 Binding of Fkbp1a and Mtor 1 0.00 0.22 0
64 INT192048 Binding of DSP and Ryr2 1 0.24 1.1 0
65 INT311391 Binding of Celf1 and Dmpk 1 0.34 0.09 0
66 INT272521 Binding of DMPK and Nkx2-5 1 0.01 0.42 0
67 INT271027 Binding of RYR1 and Car2 1 0.03 0.46 0
68 INT351095 Binding of FKBP1A and RPS6KB1 1 0.24 0.36 0
69 INT351101 Negative_regulation of Binding of FKBP1A and RPS6KB1 1 0.27 0.36 0
70 INT192042 Binding of Jup and Ryr2 1 0.17 1.09 0
71 INT266703 Binding of RYR1 and DIXDC1 1 0.26 0.1 0
72 INT296930 Casq1 Negative_regulation of RYR1 1 0.00 0.38 0
73 INT351096 Binding of FKBP1A and MTOR 1 0.28 1.35 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for sarcoplasmic reticulum membrane. They are ordered first by their pain relevance and then by number of times they were reported in sarcoplasmic reticulum membrane. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT7813 Regulation of SRI 25 0.61 6.18 8.13
2 INT18393 Negative_regulation of Ryr1 15 0.43 3.63 7.57
3 INT59555 Binding of RYR1 39 0.42 8.65 4.92
4 INT60575 Binding of Fkbp1a 9 0.26 2.09 4.46
5 INT88182 Gene_expression of Atp2a2 40 0.78 22.91 4.26
6 INT3127 Gene_expression of SRI 38 0.68 26.29 3.82
7 INT80347 Positive_regulation of Camk2b 2 0.69 0.33 3.67
8 INT18282 Binding of SRI 10 0.36 3.31 3.59
9 INT80345 Gene_expression of Camk2b 3 0.77 0.5 3.44
10 INT18396 Positive_regulation of Ryr1 10 0.58 2.45 3.38
11 INT15648 Positive_regulation of RYR1 30 0.67 12.03 3.26
12 INT18394 Regulation of Ryr1 6 0.60 0.28 3.26
13 INT26273 Negative_regulation of RYR1 18 0.43 7.64 3.11
14 INT80346 Negative_regulation of Camk2b 3 0.58 0.58 2.81
15 INT144057 Transcription of SRI 5 0.67 7.94 2.6
16 INT65603 Positive_regulation of SRI 8 0.41 2.32 2.56
17 INT88183 Localization of Atp2a2 6 0.63 2.1 2.22
18 INT102908 Phosphorylation of Camk2b 2 0.62 0.42 2.17
19 INT6508 Gene_expression of RYR1 34 0.77 11.11 2.04
20 INT99426 Negative_regulation of Gene_expression of Atp2a2 19 0.59 13.7 1.96
21 INT89639 Phosphorylation of CAMK2G 5 0.48 0.66 1.78
22 INT11713 Localization of RYR1 22 0.76 10.42 1.64
23 INT62127 Localization of SRI 12 0.45 10.21 1.54
24 INT7812 Negative_regulation of SRI 10 0.59 4.28 1.46
25 INT55305 Regulation of RYR1 14 0.45 5.27 1.33
26 INT99427 Positive_regulation of Gene_expression of Atp2a2 5 0.64 4.13 1.14
27 INT80341 Regulation of Gene_expression of Camk2b 1 0.61 0.08 1.08
28 INT116801 Negative_regulation of Positive_regulation of Camk2b 1 0.29 0.1 1.02
29 INT84386 Positive_regulation of Positive_regulation of SRI 1 0.20 0 0.96
30 INT144465 Gene_expression of DMPK 9 0.69 5.01 0.94
31 INT230251 Binding of FKBP1A 6 0.28 2.24 0.94
32 INT351265 Regulation of Binding of SRI 1 0.28 0 0.92
33 INT106495 Positive_regulation of Localization of Atp2a2 1 0.37 0.19 0.91
34 INT116831 Binding of Ryr1 11 0.47 0.12 0.9
35 INT38446 Localization of Ryr1 3 0.64 0.28 0.86
36 INT168661 Negative_regulation of Positive_regulation of SRI 1 0.02 0.37 0.79
37 INT73429 Negative_regulation of Atp2a2 20 0.20 9.05 0.74
38 INT272511 Positive_regulation of DMPK 8 0.54 6.85 0.72
39 INT168659 Regulation of Transcription of SRI 1 0.01 0.3 0.68
40 INT102906 Positive_regulation of Gene_expression of Camk2b 1 0.68 0.43 0.63
41 INT102909 Positive_regulation of Phosphorylation of Camk2b 1 0.46 0.43 0.63
42 INT18395 Negative_regulation of Negative_regulation of Ryr1 1 0.00 0 0.59
43 INT200956 Negative_regulation of CAMK2B 1 0.37 0.93 0.56
44 INT107187 Gene_expression of Atp2a1 1 0.43 0 0.52
45 INT168660 Negative_regulation of Gene_expression of SRI 2 0.04 0.26 0.51
46 INT211584 Gene_expression of Dmpk 32 0.73 12.28 0.46
47 INT137307 Regulation of Regulation of SRI 1 0.26 1.55 0.46
48 INT15647 Regulation of Positive_regulation of RYR1 1 0.26 0.23 0.45
49 INT192006 Gene_expression of RYR2 5 0.23 7.69 0.44
50 INT137835 Binding of CAMK2B 1 0.08 1.38 0.42
51 INT107188 Regulation of Gene_expression of Atp2a2 1 0.54 0 0.39
52 INT291905 Localization of ART1 1 0.01 0.27 0.38
53 INT207064 Gene_expression of Fkbp1a 2 0.32 1.52 0.34
54 INT211586 Regulation of DMPK 6 0.31 2.11 0.33
55 INT207065 Localization of Fkbp1a 1 0.36 0.82 0.33
56 INT164827 Negative_regulation of Atp2a1 1 0.43 0.15 0.32
57 INT36626 Negative_regulation of ART1 1 0.14 0.32 0.32
58 INT80636 Positive_regulation of Localization of RYR1 2 0.47 0.78 0.29
59 INT190676 Binding of Fkbp1a 15 0.36 3.11 0.28
60 INT260581 Binding of DMPK 7 0.43 5.09 0.28
61 INT202802 Regulation of Fkbp1a 4 0.26 0.96 0.28
62 INT89637 Negative_regulation of CAMK2G 1 0.26 0 0.28
63 INT118866 Positive_regulation of CAMK2G 1 0.16 0.09 0.27
64 INT26678 Negative_regulation of Dmpk 11 0.47 3.45 0.26
65 INT311550 Positive_regulation of Positive_regulation of RYR3 1 0.33 0.18 0.26
66 INT311547 Positive_regulation of RYR3 1 0.45 0.17 0.26
67 INT59650 Regulation of Binding of RYR1 1 0.04 0 0.23
68 INT120216 Regulation of RYR2 2 0.28 1.03 0.22
69 INT65834 Negative_regulation of ATP2A2 4 0.07 2.39 0.21
70 INT49908 Regulation of Gene_expression of RYR1 3 0.45 0.32 0.19
71 INT164519 Gene_expression of FKBP1A 2 0.39 0.22 0.19
72 INT311292 Positive_regulation of Positive_regulation of DMPK 1 0.36 0.77 0.18
73 INT60209 Transcription of RYR1 3 0.69 3.06 0.16
74 INT164832 Positive_regulation of Atp2a1 1 0.30 0.07 0.16
75 INT164828 Negative_regulation of Negative_regulation of Atp2a1 1 0.31 0.07 0.16
76 INT200987 Transcription of CAMK2B 2 0.44 0.2 0.14
77 INT200978 Regulation of Transcription of CAMK2B 1 0.29 0.15 0.14
78 INT255100 Positive_regulation of Gene_expression of Dmpk 8 0.56 3.3 0.13
79 INT232584 Transcription of DMPK 5 0.47 3.41 0.13
80 INT158175 Positive_regulation of Gene_expression of RYR1 2 0.48 1.35 0.13
81 INT293345 Negative_regulation of Binding of FKBP1A 1 0.02 0.19 0.13
82 INT170514 Gene_expression of Ryr1 4 0.49 0.56 0.12
83 INT255110 Binding of Dmpk 9 0.39 1.41 0.11
84 INT221472 Negative_regulation of Regulation of SRI 3 0.03 0.05 0.11
85 INT165787 Positive_regulation of RYR2 2 0.23 1.3 0.11
86 INT331573 Regulation of Localization of SRI 1 0.23 0.46 0.11
87 INT221475 Positive_regulation of Gene_expression of SRI 1 0.04 0 0.11
88 INT255117 Regulation of Localization of Dmpk 1 0.39 2.14 0.09
89 INT299319 Localization of FKBP1A 1 0.44 0 0.09
90 INT240717 Negative_regulation of Localization of Atp2a2 1 0.13 1.3 0.08
91 INT255129 Localization of Dmpk 5 0.65 3.1 0.07
92 INT178878 Regulation of Gene_expression of SRI 2 0.14 0.59 0.07
93 INT256156 Positive_regulation of ART1 1 0.01 0.21 0.07
94 INT175756 Positive_regulation of Regulation of SRI 1 0.05 0 0.07
95 INT192016 Localization of RYR2 5 0.25 4.18 0.05
96 INT192012 Binding of RYR2 2 0.30 3.61 0.05
97 INT255136 Regulation of Gene_expression of Dmpk 2 0.39 0.56 0.05
98 INT221865 Positive_regulation of Localization of RYR2 2 0.15 4.56 0.05
99 INT299313 Positive_regulation of Gene_expression of FKBP1A 1 0.29 0 0.05
100 INT271024 Negative_regulation of Binding of RYR1 3 0.05 1.07 0.04
101 INT316641 Positive_regulation of Localization of Ryr1 1 0.42 0 0.04
102 INT192023 Negative_regulation of RYR2 1 0.15 1.86 0.04
103 INT255102 Transcription of Dmpk 8 0.60 2.47 0.03
104 INT272509 Localization of DMPK 6 0.58 1.52 0.03
105 INT211585 Negative_regulation of Gene_expression of Dmpk 5 0.47 1.63 0.03
106 INT272485 Regulation of Transcription of Dmpk 4 0.50 0.56 0.03
107 INT201163 Regulation of Atp2a2 4 0.08 2.97 0.03
108 INT201169 Negative_regulation of Regulation of Atp2a2 1 0.08 0.61 0.03
109 INT221474 Positive_regulation of Localization of SRI 1 0.03 0.06 0.03
110 INT221473 Positive_regulation of Phosphorylation of SRI 1 0.03 0 0.03
111 INT201161 Positive_regulation of Regulation of Atp2a2 1 0.06 0.56 0.03
112 INT221476 Phosphorylation of SRI 1 0.05 0 0.03
113 INT322462 Transcription of Ryr2 1 0.55 0.47 0.03
114 INT266731 Binding of TRDN 1 0.47 0 0.03
115 INT255097 Positive_regulation of Dmpk 4 0.61 2.06 0
116 INT272479 Regulation of Dmpk 2 0.50 0.45 0
117 INT240720 Transcription of Atp2a2 2 0.20 1.26 0
118 INT244607 Gene_expression of CAMK2B 2 0.23 0.23 0
119 INT272472 Phosphorylation of Dmpk 2 0.72 1.05 0
120 INT219581 Binding of Ryr2 2 0.27 4.54 0
121 INT255116 Positive_regulation of Positive_regulation of Dmpk 2 0.44 1.01 0
122 INT272504 Positive_regulation of Gene_expression of DMPK 2 0.39 0.54 0
123 INT219567 Phosphorylation of Ryr2 2 0.62 0.22 0
124 INT311284 Negative_regulation of Gene_expression of DMPK 1 0.33 0.33 0
125 INT271494 Binding of ART1 1 0.01 0.66 0
126 INT272481 Negative_regulation of Phosphorylation of Dmpk 1 0.41 0.44 0
127 INT219566 Localization of Ryr2 1 0.45 0.49 0
128 INT211904 Negative_regulation of Localization of RYR1 1 0.37 0.64 0
129 INT330573 Gene_expression of ART1 1 0.01 0.5 0
130 INT272506 Negative_regulation of Localization of DMPK 1 0.29 0.41 0
131 INT311334 Positive_regulation of Localization of Dmpk 1 0.38 0.76 0
132 INT296913 Positive_regulation of Transcription of Atp2a2 1 0.02 1.33 0
133 INT255202 Gene_expression of ATP2A2 1 0.65 0.41 0
134 INT322461 Negative_regulation of Transcription of Ryr2 1 0.45 0 0
135 INT219582 Positive_regulation of Phosphorylation of Ryr2 1 0.30 0.22 0
136 INT192020 Regulation of Localization of RYR2 1 0.15 0.27 0
137 INT53281 Regulation of Atp2a1 1 0.11 0 0
138 INT311313 Negative_regulation of Transcription of Dmpk 1 0.38 0 0
139 INT311309 Protein_catabolism of Dmpk 1 0.67 0.62 0
140 INT311335 Negative_regulation of Localization of Dmpk 1 0.33 0 0
141 INT311303 Regulation of Protein_catabolism of Dmpk 1 0.21 0.07 0
142 INT80635 Regulation of Localization of RYR1 1 0.04 0.1 0
143 INT211903 Negative_regulation of Gene_expression of RYR1 1 0.37 0.06 0
144 INT296912 Positive_regulation of Atp2a2 1 0.02 0.66 0
145 INT297204 Regulation of Ryr2 1 0.08 0.3 0
146 INT232582 Negative_regulation of DMPK 1 0.00 0.42 0
147 INT354089 Positive_regulation of Transcription of CAMK2B 1 0.09 0.05 0
148 INT240721 Negative_regulation of Negative_regulation of Atp2a2 1 0.13 1.07 0
149 INT296924 Positive_regulation of Positive_regulation of Atp2a2 1 0.02 0.67 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox