GO:0033077

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Name T cell differentiation in thymus
Categary Process
Go Slim No
Go Link GO:0033077
Unique Molecular Interactions 649
Total Molecular Interactions 810
Total Single Events 7267
Pain Genes Associated 40

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for T cell differentiation in thymus. They are ordered first by their pain relevance and then by number of times they were reported for T cell differentiation in thymus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT206768 TP53 Positive_regulation of Ltp 2 0.01 5.83 10.21
2 INT156008 Bcl2 Regulation of Localization of Aifm1 1 0.17 1.92 1.47
3 INT145930 ecs Positive_regulation of Gene_expression of Bcl2 1 0.01 2.06 1.34
4 INT84886 APC Regulation of PPARD 1 0.51 1.57 1.26
5 INT142202 FL Positive_regulation of Bcl2 1 0.05 0.39 0.99
6 INT73461 PTPLA Positive_regulation of Transcription of TP53 1 0.06 0.99 0.96
7 INT330629 TP53 Negative_regulation of Gene_expression of Fos 1 0.30 1.76 0.94
8 INT210799 Bmp2 Positive_regulation of B2m 1 0.35 0.52 0.92
9 INT112765 Binding of Nfkb1 and Bcl2 1 0.00 1.37 0.91
10 INT210789 Bst2 Positive_regulation of B2m 1 0.32 0.54 0.89
11 INT166634 Binding of Bcl2 and Becn1 1 0.20 0.5 0.86
12 INT330630 Binding of TP53 and Car1 1 0.23 1.56 0.86
13 INT150864 RYBP Positive_regulation of Positive_regulation of Bcl2 1 0.01 0.66 0.86
14 INT140985 Gli3 Regulation of Ihh 1 0.29 0.85 0.85
15 INT167944 Binding of Oprm1 and Stat5a 1 0.00 0 0.85
16 INT97057 Bcl2l1 Regulation of Gene_expression of Trp53 1 0.36 0.51 0.83
17 INT97058 Cpz Regulation of Gene_expression of Trp53 1 0.27 0.57 0.83
18 INT322266 Binding of LIG4 and NOS3 1 0.02 2.35 0.82
19 INT117341 ADAM17 Positive_regulation of EGFR 1 0.16 3.56 0.82
20 INT102162 Binding of TNF and Adam17 1 0.14 0.88 0.78
21 INT102159 Binding of Adam17 and Mmp2 1 0.18 0.87 0.77
22 INT117412 RYBP Negative_regulation of LIG4 1 0.00 0.42 0.76
23 INT218935 Cyp3a23/3a1 Regulation of Bcl2 1 0.00 1.08 0.74
24 INT195778 Binding of APC and PROCR 7 0.19 3.78 0.73
25 INT314203 Nos2 Positive_regulation of Gli3 1 0.19 1.27 0.73
26 INT320633 Positive_regulation of MAPK1 Regulation of BCL2 1 0.04 1.21 0.7
27 INT104301 Adam17 Regulation of Negative_regulation of Sell 1 0.39 0.58 0.69
28 INT68561 Binding of Gli3 and Ust 1 0.01 0.68 0.68
29 INT101986 TP53 Positive_regulation of Gene_expression of GDF15 1 0.52 2.45 0.67
30 INT296785 Tlr9 Regulation of Bcl2 1 0.19 0.76 0.65
31 INT126614 Ppyr1 Negative_regulation of Phosphorylation of Stat5a 1 0.27 0.1 0.64
32 INT166402 CDKN1A Regulation of Gene_expression of TP53 1 0.27 0.83 0.61
33 INT126615 Binding of Oprd1 and Stat5a 1 0.28 0.07 0.61
34 INT129270 Binding of Wnt4 and Efs 1 0.00 0 0.55
35 INT254200 Mif Regulation of Trp53 1 0.02 0.96 0.52
36 INT184130 Epo Positive_regulation of Stat5a 1 0.31 0.26 0.52
37 INT184096 Il7 Positive_regulation of Stat5a 1 0.07 0.26 0.51
38 INT184132 Il2 Positive_regulation of Stat5a 1 0.09 0.26 0.51
39 INT322048 Prkdc Negative_regulation of Col7a1 1 0.00 0.45 0.5
40 INT182150 Binding of APC and DCPS 1 0.02 1.14 0.48
41 INT114297 Apc Negative_regulation of Gene_expression of Fcer2a 1 0.03 0.96 0.48
42 INT302839 MIR15A Negative_regulation of Bcl2 1 0.15 1.41 0.47
43 INT238639 Cd86 Negative_regulation of Negative_regulation of Bcl2 1 0.01 0.97 0.46
44 INT112772 Binding of Bcl2 and SGSM3 1 0.02 0.69 0.45
45 INT116609 Lnpep Negative_regulation of Bcl2 1 0.05 0.62 0.43
46 INT116606 Lnpep Regulation of Gene_expression of Bcl2 1 0.07 0.62 0.43
47 INT302829 Mapkapk5 Positive_regulation of Trp53 1 0.07 0.81 0.43
48 INT116607 Lnpep Negative_regulation of Gene_expression of Bcl2 1 0.10 0.62 0.43
49 INT309143 Dlat Positive_regulation of Bcl2 1 0.06 1.04 0.42
50 INT309152 Dlat Positive_regulation of Gene_expression of Bcl2 1 0.04 1.05 0.42
51 INT228055 WNT1 Positive_regulation of CTNND2 1 0.54 1.75 0.42
52 INT167946 Binding of SRC and Stat5b 1 0.28 0 0.38
53 INT235878 Creb1 Positive_regulation of Gene_expression of Bcl2 1 0.05 0.17 0.38
54 INT300609 Binding of Ctnnb1 and Wnt2 1 0.02 0.25 0.37
55 INT84887 APC Negative_regulation of Gene_expression of PPARD 1 0.36 0.55 0.37
56 INT155062 Csf2 Positive_regulation of Transcription of Bcl2 1 0.31 2.91 0.36
57 INT264555 IL15 Positive_regulation of Gene_expression of BCL2 1 0.02 0.92 0.35
58 INT124378 Prodh2 Positive_regulation of Ctnnb1 1 0.00 0.59 0.35
59 INT269962 Bcl2 Negative_regulation of Bcl2l11 1 0.15 2.14 0.34
60 INT155060 Stat3 Negative_regulation of Bcl2 1 0.21 3.7 0.33
61 INT91814 Binding of TNF and TP53 1 0.14 2.2 0.32
62 INT195665 APC Negative_regulation of F8 1 0.04 1.53 0.32
63 INT242164 Wnt2 Positive_regulation of Localization of Apc 1 0.13 1.53 0.32
64 INT166394 CDKN1B Regulation of Gene_expression of TP53 1 0.28 0.41 0.31
65 INT166396 IFI27 Regulation of Gene_expression of TP53 1 0.19 0.41 0.31
66 INT195664 APC Negative_regulation of F5 1 0.08 1.51 0.31
67 INT63122 Binding of APC and Man2a2 1 0.01 0.15 0.3
68 INT242398 Cyp19a1 Positive_regulation of Bcl2 1 0.00 1.28 0.3
69 INT333917 MDM2 Positive_regulation of Protein_catabolism of Trp53 1 0.01 1.23 0.3
70 INT333918 HDAC1 Regulation of Trp53 1 0.03 1.24 0.3
71 INT163761 MDM2 Positive_regulation of Gene_expression of TP53 1 0.40 0.86 0.3
72 INT166952 LYRM4 Positive_regulation of Gene_expression of TP53 1 0.05 0.75 0.28
73 INT218928 Cyp3a23/3a1 Regulation of Transcription of Bcl2 1 0.00 0.56 0.28
74 INT260837 NRP2 Negative_regulation of Negative_regulation of Bcl2 1 0.00 0.9 0.28
75 INT289954 Binding of APC and CD28 1 0.03 0.38 0.28
76 INT286042 Binding of Tp53 and Wwox 1 0.04 2.05 0.28
77 INT216127 EGR1 Regulation of Transcription of TP53 1 0.06 0.21 0.28
78 INT302837 Binding of TNFRSF10D and Trp53 1 0.01 0.98 0.28
79 INT172905 Binding of Bad and Bcl2 3 0.08 6.46 0.27
80 INT306267 Binding of INCENP and TP53 1 0.02 0.83 0.27
81 INT350813 Binding of Apc and Crp 1 0.18 1.12 0.27
82 INT216128 EGR1 Regulation of TP53 1 0.11 0.21 0.27
83 INT237927 BCL2 Positive_regulation of BAX 2 0.24 2.22 0.26
84 INT237928 BCL2 Positive_regulation of FAS 1 0.02 1.41 0.26
85 INT272157 Gh1 Negative_regulation of Bcl2 1 0.23 1.2 0.26
86 INT272158 Gh1 Regulation of Bcl2 1 0.15 1.2 0.26
87 INT352931 Prkaca Regulation of TP53 1 0.13 1.01 0.26
88 INT352930 Prkaca Regulation of Phosphorylation of TP53 1 0.13 1.02 0.26
89 INT125514 Positive_regulation of PRKDC Positive_regulation of Positive_regulation of NFKB1 1 0.07 0.44 0.26
90 INT237925 BCL2 Positive_regulation of Protein_catabolism of PARP1 1 0.02 1.42 0.26
91 INT182325 TP53 Negative_regulation of Transcription of Birc5 1 0.01 1.34 0.26
92 INT172975 Trp53 Positive_regulation of Cdkn1a 1 0.03 1.35 0.26
93 INT235013 Binding of DSG1 and Adam17 1 0.07 1.34 0.26
94 INT352893 PTGDS Regulation of TP53 1 0.16 1.02 0.26
95 INT125516 TP53 Regulation of GDF15 1 0.10 0.47 0.26
96 INT234980 Positive_regulation of Egfr Positive_regulation of Adam17 1 0.09 1.33 0.26
97 INT166664 Mpzl2 Negative_regulation of Mmp9 1 0.31 0.32 0.25
98 INT337086 Mif Negative_regulation of Localization of Trp53 1 0.16 1.64 0.25
99 INT337091 Mif Negative_regulation of Positive_regulation of Trp53 1 0.16 1.64 0.25
100 INT166662 Mpzl2 Negative_regulation of Positive_regulation of Mmp9 1 0.31 0.32 0.25
101 INT235976 Binding of APC and Trav6-3 2 0.01 2.62 0.24
102 INT235974 Negative_regulation of Binding of APC and Trav6-3 1 0.00 1.15 0.24
103 INT156879 Gene_expression of TP53 Negative_regulation of Positive_regulation of PDF 1 0.45 0.9 0.24
104 INT260840 NRP2 Positive_regulation of Gene_expression of Bcl2 1 0.00 0.85 0.24
105 INT181900 TP53 Negative_regulation of Gene_expression of NOS1 1 0.03 0.94 0.24
106 INT235972 Negative_regulation of Binding of APC and Bcr 1 0.01 1.15 0.24
107 INT235973 Binding of APC and Bcr 1 0.01 1.14 0.24
108 INT166663 Mpzl2 Negative_regulation of Positive_regulation of Ptgs2 1 0.29 0.3 0.24
109 INT156881 TP53 Positive_regulation of Positive_regulation of PDF 1 0.49 0.89 0.24
110 INT109408 Negative_regulation of APC Negative_regulation of Positive_regulation of RASGRP1 1 0.06 0.73 0.23
111 INT229177 IFRD1 Regulation of TP53 1 0.13 0.68 0.23
112 INT250783 APC Negative_regulation of SERPINE1 1 0.06 0.86 0.23
113 INT302170 PTGER2 Positive_regulation of Gene_expression of BCL2 1 0.04 3.76 0.23
114 INT250782 APC Negative_regulation of F2 1 0.00 0.86 0.23
115 INT316111 APC Negative_regulation of SAE1 1 0.04 1.21 0.22
116 INT226902 Padi3 Regulation of Trp53 1 0.06 0.69 0.22
117 INT195663 APC Negative_regulation of Gene_expression of IL6 1 0.16 1.18 0.22
118 INT229178 TP53 Regulation of ICAM1 1 0.07 0.9 0.21
119 INT156882 Binding of TP53 and PDF 1 0.39 0.77 0.21
120 INT156880 TP53 Positive_regulation of Gene_expression of PDF 1 0.49 0.75 0.21
121 INT316110 Binding of APC and SAE1 1 0.03 1.16 0.2
122 INT210887 Sst Positive_regulation of Gene_expression of Trp53 1 0.33 0.93 0.2
123 INT256629 Binding of Ptch1 and Shh 7 0.42 4.22 0.19
124 INT193787 Positive_regulation of CXCR4 Positive_regulation of Positive_regulation of TP53 1 0.03 0.71 0.19
125 INT142853 Binding of TP53 and WISP2 1 0.33 1.43 0.19
126 INT176133 AKT1 Regulation of BCL2 2 0.12 1.84 0.17
127 INT285026 Bak1 Regulation of Bcl2 1 0.09 0.71 0.17
128 INT285022 Regulation of Bak1 Regulation of Bcl2 1 0.09 0.71 0.17
129 INT349475 Regulation of Bax Regulation of Bcl2 1 0.07 1.35 0.17
130 INT155233 TXNIP Regulation of BCL2 1 0.23 0.15 0.17
131 INT285024 Bcl2 Regulation of Bak1 1 0.09 0.71 0.17
132 INT334106 APC Negative_regulation of NFKB1 1 0.25 1.37 0.17
133 INT229203 Binding of Bcl2 and Cyp2c11 1 0.36 1.2 0.17
134 INT179846 Il11 Regulation of Positive_regulation of Rps6 1 0.04 0.07 0.17
135 INT155068 Csf2 Negative_regulation of Bcl2 1 0.12 1.88 0.17
136 INT102804 NFKB1 Regulation of TP53 1 0.35 0.77 0.17
137 INT334108 APC Negative_regulation of TNF 1 0.13 1.36 0.17
138 INT102803 NFKB1 Regulation of Gene_expression of TP53 1 0.35 0.77 0.17
139 INT91812 Binding of FASLG and TP53 1 0.04 1.1 0.16
140 INT347445 CD99 Positive_regulation of BCL2 1 0.17 0.95 0.16
141 INT91811 Binding of FAS and TP53 1 0.21 1.1 0.16
142 INT194829 Gata3 Positive_regulation of IL13 1 0.01 0.12 0.15
143 INT292750 Akt1 Positive_regulation of Bcl2 1 0.01 1.67 0.15
144 INT194835 Gata3 Positive_regulation of IL5 1 0.01 0.12 0.15
145 INT349476 Bax Regulation of Bcl2 1 0.07 1.33 0.15
146 INT266377 Binding of S100a11 and Trp53 1 0.02 0.89 0.15
147 INT194833 Binding of IL5 and Gata3 1 0.01 0.12 0.15
148 INT194827 Binding of IL13 and Gata3 1 0.01 0.12 0.15
149 INT311666 Binding of BCL2 and TP53 1 0.19 1.26 0.14
150 INT223538 Binding of HAND1 and Tcf3 1 0.39 1.13 0.14
151 INT95104 TGFBR2 Positive_regulation of BCL2 1 0.08 0.61 0.14
152 INT309139 Edc4 Positive_regulation of Bcl2 1 0.03 0.12 0.13
153 INT103557 Binding of ERCC2 and TP53 1 0.40 1 0.13
154 INT148594 Binding of BCL2 and CD34 1 0.39 1.17 0.13
155 INT289956 Binding of APC and ICAM1 1 0.04 0.5 0.13
156 INT184129 Socs2 Negative_regulation of Stat5a 1 0.22 0.05 0.13
157 INT132148 LTF Positive_regulation of TP53 1 0.44 0.56 0.13
158 INT242163 Wnt2 Positive_regulation of Regulation of Apc 1 0.13 0.71 0.13
159 INT309142 Edc4 Regulation of Bcl2 1 0.02 0.12 0.13
160 INT246016 Negative_regulation of Timp1 Negative_regulation of Gene_expression of Bcl2 1 0.03 1.07 0.13
161 INT251115 Positive_regulation of Binding of AR and Ctnnb1 1 0.01 1.02 0.13
162 INT103561 Binding of TP53 and Mc1r 1 0.03 1 0.13
163 INT338428 Il4 Positive_regulation of Gata3 1 0.06 0.75 0.13
164 INT184603 APC Negative_regulation of Gene_expression of TNF 1 0.09 0.97 0.13
165 INT223530 Binding of Tcf3 and Szf1 1 0.33 0.92 0.13
166 INT342311 Binding of Tp53 and Positive_regulation of Gene_expression of BCL2 1 0.08 1.25 0.13
167 INT348542 BCL2 Negative_regulation of NLRP1 1 0.07 2.02 0.13
168 INT246017 Timp1 Negative_regulation of Gene_expression of Bcl2 1 0.03 1.07 0.13
169 INT223526 Binding of Pax6 and Tcf3 1 0.33 0.92 0.13
170 INT172899 Binding of Bcl2 and Bcl2l1 3 0.02 5.54 0.12
171 INT178101 EDN1 Negative_regulation of Phosphorylation of BCL2 1 0.03 1 0.12
172 INT305194 Bcl2 Positive_regulation of Epo 1 0.06 0.29 0.12
173 INT316190 Apc Negative_regulation of Positive_regulation of Mapk1 1 0.33 0.66 0.12
174 INT184608 APC Regulation of Gene_expression of Nppa 1 0.06 1.11 0.12
175 INT251114 Binding of AR and Ctnnb1 1 0.01 1 0.12
176 INT299754 Binding of APC and CTLA4 2 0.08 0.97 0.11
177 INT83370 Binding of HRAS and TP53 1 0.30 0.59 0.11
178 INT350736 PRKDC Negative_regulation of CA2 1 0.02 0.16 0.11
179 INT273063 Negative_regulation of Fas Negative_regulation of Positive_regulation of Bcl2 1 0.01 0.72 0.11
180 INT259629 Binding of Adam17 and Timp3 1 0.01 0.19 0.11
181 INT350735 PRKDC Negative_regulation of ITPR3 1 0.01 0.16 0.11
182 INT221684 Binding of Bcl2 and FRTS 1 0.01 1.19 0.11
183 INT265888 BCL2 Regulation of Gene_expression of BAD 1 0.04 1.08 0.1
184 INT266386 Binding of S100a1 and Trp53 1 0.03 0.64 0.1
185 INT265890 BCL2 Regulation of Gene_expression of BAX 1 0.04 1.08 0.1
186 INT298267 Tcf3 Positive_regulation of Gene_expression of Runx1 1 0.21 0.6 0.1
187 INT193782 Binding of TP53 and SDF2L1 1 0.00 0.67 0.1
188 INT184089 Gh Positive_regulation of Stat5b 1 0.13 1.3 0.1
189 INT262522 Binding of Trp53 and Foxo4 1 0.05 0.7 0.1
190 INT287887 WNT1 Positive_regulation of Localization of BMP4 1 0.04 1.13 0.1
191 INT310743 TP53 Regulation of BAX 1 0.09 1.11 0.1
192 INT262255 Binding of APC and F2R 1 0.05 3 0.1
193 INT239643 Binding of BCL2 and BCL2L11 3 0.16 2.26 0.09
194 INT282094 Apoa2 Negative_regulation of BCL2 1 0.06 1.15 0.09
195 INT326126 Binding of S100A1 and TP53 1 0.04 1.34 0.09
196 INT132266 Binding of HLA-B and B2m 1 0.02 0.14 0.09
197 INT275183 Bad Positive_regulation of Gene_expression of Bcl2 1 0.08 0.63 0.09
198 INT265887 IGF1 Negative_regulation of BCL2 1 0.09 1.02 0.09
199 INT294637 Bcl2a1a Positive_regulation of Gene_expression of Bcl2 1 0.15 0.97 0.09
200 INT352611 Trp53 Negative_regulation of Localization of Gli1 1 0.23 1.2 0.09

Single Events

The table below shows the top 100 pain related interactions that have been reported for T cell differentiation in thymus. They are ordered first by their pain relevance and then by number of times they were reported in T cell differentiation in thymus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03
2 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38
3 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73
4 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8
5 INT93734 Positive_regulation of Gene_expression of Bcl2 76 0.70 61.95 18.46
6 INT86673 Positive_regulation of Bcl2 77 0.70 57.74 17.37
7 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71
8 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65
9 INT80972 Gene_expression of Tp53 104 0.78 102.74 16.02
10 INT80222 Negative_regulation of Bcl2 82 0.58 69.16 13.18
11 INT81640 Positive_regulation of Gene_expression of Bcl2 106 0.69 84.58 11.63
12 INT169997 Positive_regulation of Gene_expression of Tp53 37 0.70 47.3 9.85
13 INT57057 Gene_expression of APC 131 0.78 122.24 8.7
14 INT70017 Positive_regulation of BCL2 87 0.67 66.62 8.68
15 INT670 Gene_expression of B2m 31 0.66 27.32 8.49
16 INT86672 Negative_regulation of Bcl2 50 0.53 34.16 8.37
17 INT65959 Positive_regulation of Gene_expression of BCL2 75 0.70 77.3 8.27
18 INT80220 Positive_regulation of Bcl2 71 0.58 57.73 7.86
19 INT77306 Negative_regulation of Gene_expression of Bcl2 46 0.58 38.05 7.71
20 INT57748 Positive_regulation of Gene_expression of TP53 85 0.69 79.55 7.49
21 INT91445 Regulation of Bcl2 50 0.56 38.8 7.41
22 INT97055 Positive_regulation of Gene_expression of Trp53 51 0.70 45.7 7.25
23 INT16631 Negative_regulation of APC 46 0.57 30.53 7.11
24 INT93101 Regulation of Gene_expression of Bcl2 26 0.62 18.45 6.71
25 INT84685 Regulation of BCL2 67 0.60 72.96 6.65
26 INT130875 Gene_expression of ADAM17 13 0.78 15.46 6.41
27 INT93359 Positive_regulation of Trp53 90 0.70 69.77 6.24
28 INT3819 Positive_regulation of Apc 36 0.69 27.03 6.02
29 INT112545 Phosphorylation of TP53 28 0.80 14.13 5.93
30 INT100422 Negative_regulation of Gene_expression of Bcl2 46 0.58 28.86 5.7
31 INT87022 Gene_expression of Apc 68 0.67 46.98 5.22
32 INT70613 Negative_regulation of Gene_expression of BCL2 48 0.59 38.91 5.22
33 INT60585 Regulation of TP53 59 0.59 54.55 5.21
34 INT57064 Positive_regulation of APC 72 0.66 48.5 5.08
35 INT73262 Negative_regulation of BCL2 67 0.57 61.01 5.07
36 INT68559 Negative_regulation of Gli3 5 0.37 4.56 4.93
37 INT673 Positive_regulation of B2m 24 0.68 24.24 4.82
38 INT109972 Phosphorylation of Trp53 13 0.80 6.15 4.68
39 INT62684 Negative_regulation of TP53 66 0.58 66.09 4.62
40 INT57749 Negative_regulation of Gene_expression of TP53 39 0.56 36.79 4.45
41 INT104299 Negative_regulation of Adam17 18 0.47 12.03 4.39
42 INT126608 Binding of Stat5a 7 0.48 0.46 4.38
43 INT101957 Transcription of Bcl2 30 0.69 16.57 4.3
44 INT116011 Positive_regulation of Gata3 5 0.31 3.17 4.21
45 INT202417 Gene_expression of Gata3 16 0.61 7.84 4.12
46 INT3817 Negative_regulation of Apc 29 0.58 22.12 3.91
47 INT63121 Binding of APC 29 0.41 23.02 3.8
48 INT105882 Phosphorylation of Bcl2 11 0.59 8.15 3.73
49 INT71602 Negative_regulation of Trp53 84 0.59 67.77 3.68
50 INT109403 Regulation of Gene_expression of BCL2 31 0.60 31.22 3.4
51 INT81642 Regulation of Gene_expression of Bcl2 20 0.44 16.93 3.19
52 INT64234 Regulation of Bcl2 41 0.54 31.88 3.16
53 INT72618 Regulation of Tcf3 5 0.44 1.48 3.16
54 INT21678 Negative_regulation of B2m 20 0.55 10.11 3.12
55 INT105884 Binding of Bcl2 19 0.35 15.67 3
56 INT8103 Binding of TP53 46 0.44 40.2 2.96
57 INT101567 Gene_expression of Ctnnb1 7 0.64 10.11 2.89
58 INT102157 Gene_expression of Adam17 3 0.58 4.17 2.86
59 INT109969 Positive_regulation of Phosphorylation of Trp53 1 0.45 2.18 2.66
60 INT202419 Positive_regulation of Gene_expression of Gata3 6 0.52 5.47 2.6
61 INT126610 Phosphorylation of Stat5a 5 0.82 0.8 2.52
62 INT109968 Positive_regulation of Positive_regulation of Trp53 6 0.47 3.57 2.51
63 INT126581 Positive_regulation of Gli3 6 0.35 1.59 2.48
64 INT55952 Transcription of TP53 16 0.61 12.14 2.36
65 INT147349 Localization of Bcl2 13 0.65 7.83 2.31
66 INT108148 Positive_regulation of Prkdc 2 0.16 0.49 2.31
67 INT142677 Negative_regulation of Positive_regulation of Bcl2 4 0.36 3.09 2.24
68 INT117415 Negative_regulation of LIG4 4 0.04 1.59 2.17
69 INT141833 Gene_expression of WNT1 14 0.75 10.57 2.1
70 INT72616 Negative_regulation of Tcf3 2 0.41 0.97 2.04
71 INT86671 Negative_regulation of Positive_regulation of Bcl2 6 0.57 3.83 2.03
72 INT126374 Gene_expression of Gli3 6 0.77 3.67 2.02
73 INT29035 Negative_regulation of Wnt1 3 0.41 1.47 2
74 INT125080 Positive_regulation of Positive_regulation of TP53 21 0.58 16.16 1.98
75 INT81641 Gene_expression of Ctnnb1 23 0.72 14.93 1.97
76 INT144973 Gene_expression of Shh 9 0.77 4.32 1.96
77 INT146793 Positive_regulation of Tp53 30 0.70 32.93 1.94
78 INT65855 Localization of TP53 18 0.76 17.08 1.89
79 INT101108 Localization of Bcl2 16 0.72 11.68 1.86
80 INT105883 Positive_regulation of Phosphorylation of Bcl2 8 0.32 5.67 1.86
81 INT117346 Positive_regulation of ADAM17 5 0.50 6.69 1.86
82 INT113345 Positive_regulation of Phosphorylation of TP53 8 0.66 6.11 1.8
83 INT126609 Positive_regulation of Phosphorylation of Stat5a 1 0.69 0.26 1.79
84 INT208561 Gene_expression of Shh 51 0.78 9.57 1.77
85 INT130874 Negative_regulation of Gene_expression of ADAM17 3 0.43 5.03 1.76
86 INT3818 Regulation of Apc 13 0.39 12.52 1.68
87 INT101958 Positive_regulation of Transcription of Bcl2 4 0.50 2.22 1.65
88 INT123990 Positive_regulation of Ctnnb1 8 0.43 2.85 1.63
89 INT137513 Negative_regulation of Positive_regulation of BCL2 6 0.35 5.3 1.62
90 INT99391 Localization of Ctnnb1 7 0.80 5.84 1.61
91 INT130332 Gene_expression of Adam17 14 0.50 4.84 1.56
92 INT64233 Regulation of Trp53 35 0.62 27.11 1.53
93 INT120004 Transcription of Tp53 8 0.72 4.92 1.48
94 INT116014 Transcription of Gata3 4 0.63 2.24 1.46
95 INT140245 Binding of Gli3 3 0.36 2.65 1.46
96 INT101990 Negative_regulation of Positive_regulation of TP53 5 0.33 3.69 1.42
97 INT162469 Positive_regulation of Protein_catabolism of TP53 5 0.52 5.48 1.42
98 INT116015 Regulation of Gata3 3 0.22 1.41 1.42
99 INT118155 Regulation of Positive_regulation of Prkdc 1 0.10 0.49 1.42
100 INT172953 Binding of Trp53 33 0.37 20.76 1.41
101 INT93357 Regulation of Gene_expression of Trp53 15 0.62 13.4 1.41
102 INT162462 Protein_catabolism of TP53 8 0.86 7.89 1.41
103 INT116008 Binding of Gata3 2 0.34 1.37 1.41
104 INT220177 Binding of Apc 21 0.37 15.34 1.37
105 INT145221 Binding of Tp53 10 0.37 8.59 1.37
106 INT78861 Negative_regulation of Transcription of Adam17 2 0.29 1.4 1.32
107 INT78859 Transcription of Adam17 2 0.47 1.39 1.31
108 INT110434 Positive_regulation of Gene_expression of Apc 20 0.50 11.37 1.3
109 INT101107 Positive_regulation of Localization of Bcl2 3 0.48 3.13 1.28
110 INT116016 Positive_regulation of Positive_regulation of Gata3 2 0.21 0.5 1.28
111 INT126605 Negative_regulation of Binding of Stat5a 1 0.58 0.15 1.27
112 INT234893 Positive_regulation of Adam17 4 0.38 3.78 1.22
113 INT99389 Negative_regulation of Ctnnb1 8 0.45 3.97 1.21
114 INT125525 Positive_regulation of PRKDC 7 0.45 2.72 1.21
115 INT141834 Negative_regulation of Gene_expression of WNT1 3 0.57 1.31 1.2
116 INT72614 Negative_regulation of Regulation of Tcf3 1 0.41 0.17 1.2
117 INT174156 Localization of Trp53 16 0.72 13.52 1.18
118 INT116436 Negative_regulation of Phosphorylation of TP53 2 0.40 0.94 1.16
119 INT102073 Regulation of Gene_expression of APC 5 0.45 6.09 1.15
120 INT253191 Positive_regulation of Gene_expression of Shh 2 0.66 2.57 1.14
121 INT134661 Negative_regulation of Tp53 11 0.43 10.91 1.13
122 INT102074 Positive_regulation of Gene_expression of APC 20 0.50 13.66 1.1
123 INT172855 Binding of Bcl2 37 0.32 23.41 1.09
124 INT70021 Localization of BCL2 23 0.74 21.6 1.09
125 INT101570 Positive_regulation of Gene_expression of Ctnnb1 1 0.58 5.7 1.07
126 INT165530 Positive_regulation of Shh 4 0.69 1.21 1.05
127 INT132435 Negative_regulation of ADAM17 2 0.50 3.75 1.02
128 INT97052 Transcription of Trp53 12 0.64 6.52 1.01
129 INT672 Positive_regulation of Gene_expression of B2m 2 0.44 1.95 0.96
130 INT166935 Gene_expression of Prkdc 10 0.65 3.14 0.9
131 INT242134 Localization of Apc 8 0.74 4.83 0.88
132 INT151115 Regulation of Regulation of Bcl2 4 0.21 4.12 0.88
133 INT101566 Negative_regulation of Gene_expression of Ctnnb1 1 0.35 2.28 0.88
134 INT92117 Phosphorylation of BCL2 26 0.80 9.93 0.86
135 INT184015 Positive_regulation of Stat5a 9 0.46 3.32 0.86
136 INT167938 Positive_regulation of Phosphorylation of Stat5b 1 0.33 0 0.85
137 INT141835 Negative_regulation of WNT1 2 0.41 1.02 0.83
138 INT202628 Gene_expression of Wnt1 20 0.67 9.2 0.82
139 INT167942 Binding of Stat5b 1 0.26 0 0.82
140 INT93356 Negative_regulation of Gene_expression of Trp53 28 0.53 20.61 0.8
141 INT70019 Binding of BCL2 25 0.47 17.55 0.79
142 INT132127 Positive_regulation of Rps6 1 0.49 0.32 0.79
143 INT30050 Gene_expression of Tcf3 13 0.48 2.57 0.77
144 INT109404 Transcription of BCL2 6 0.69 4.49 0.77
145 INT102813 Regulation of Gene_expression of TP53 25 0.59 25.95 0.75
146 INT124844 Regulation of Positive_regulation of Bcl2 3 0.43 2.55 0.75
147 INT168245 Positive_regulation of Transcription of Tp53 2 0.70 2.63 0.75
148 INT125526 Gene_expression of PRKDC 5 0.58 4 0.74
149 INT155392 Negative_regulation of Negative_regulation of Bcl2 3 0.21 1.64 0.74
150 INT162470 Negative_regulation of Protein_catabolism of TP53 1 0.32 1.24 0.74
151 INT134444 Positive_regulation of Binding of Bcl2 3 0.47 2.67 0.72
152 INT116012 Regulation of Positive_regulation of Gata3 1 0.20 0.07 0.71
153 INT57062 Regulation of APC 24 0.58 14.3 0.7
154 INT116006 Positive_regulation of Transcription of Gata3 1 0.21 0.07 0.7
155 INT116010 Positive_regulation of Binding of Gata3 1 0.31 0.07 0.7
156 INT80674 Negative_regulation of Gene_expression of APC 16 0.59 18.14 0.69
157 INT68560 Regulation of Gli3 3 0.18 1.51 0.68
158 INT99390 Regulation of Ctnnb1 4 0.62 3.12 0.64
159 INT202416 Negative_regulation of Gata3 2 0.32 1.17 0.64
160 INT126606 Negative_regulation of Stat5a 1 0.43 0.08 0.64
161 INT159942 Positive_regulation of Stat5a 3 0.41 0.95 0.61
162 INT126612 Negative_regulation of Phosphorylation of Stat5a 1 0.42 0.1 0.61
163 INT93358 Negative_regulation of Positive_regulation of Trp53 9 0.41 3.95 0.6
164 INT53950 Phosphorylation of Tp53 8 0.61 9.4 0.6
165 INT290660 Negative_regulation of Gene_expression of Gata3 1 0.25 1.52 0.6
166 INT105266 Localization of Tcf3 3 0.32 1.08 0.59
167 INT70025 Positive_regulation of Positive_regulation of BCL2 3 0.27 0.96 0.58
168 INT333877 Protein_catabolism of LIG4 2 0.03 2.03 0.57
169 INT178128 Negative_regulation of Phosphorylation of BCL2 7 0.27 3.94 0.56
170 INT138678 Transcription of ADAM17 1 0.69 4.9 0.56
171 INT267269 Gene_expression of BCL11B 62 0.78 48.75 0.55
172 INT155090 Regulation of Positive_regulation of BCL2 3 0.26 1.78 0.54
173 INT72869 Regulation of Negative_regulation of APC 2 0.36 1.7 0.54
174 INT232453 Negative_regulation of DNAJA3 1 0.41 0 0.54
175 INT76960 Negative_regulation of Ctnnb1 5 0.57 3.46 0.53
176 INT27710 Binding of B2m 5 0.36 3.54 0.53
177 INT135062 Transcription of Gli3 1 0.05 0 0.52
178 INT144696 Regulation of Transcription of Bcl2 5 0.44 2.96 0.51
179 INT138676 Localization of ADAM17 4 0.73 4.91 0.5
180 INT286035 Negative_regulation of Gene_expression of Tp53 5 0.32 6.2 0.49
181 INT134445 Positive_regulation of Positive_regulation of Bcl2 3 0.47 2.43 0.49
182 INT221676 Protein_catabolism of Bcl2 4 0.24 2.77 0.48
183 INT81645 Positive_regulation of Gene_expression of Ctnnb1 6 0.63 3.78 0.47
184 INT19023 Localization of B2m 6 0.75 5.15 0.46
185 INT151720 Negative_regulation of Positive_regulation of Apc 3 0.37 2.15 0.46
186 INT206484 Localization of Shh 2 0.75 1.14 0.46
187 INT204052 Transcription of Bcl2 5 0.51 3.25 0.45
188 INT232798 Positive_regulation of Gene_expression of Shh 7 0.70 1.49 0.44
189 INT140295 Protein_catabolism of BCL2 4 0.64 5.7 0.44
190 INT220424 Positive_regulation of Negative_regulation of Bcl2 2 0.14 1.81 0.44
191 INT228057 Positive_regulation of WNT1 1 0.49 1.8 0.44
192 INT152151 Regulation of Gene_expression of Apc 4 0.44 3.87 0.42
193 INT167941 Phosphorylation of Stat5b 1 0.58 0 0.42
194 INT76958 Positive_regulation of Ctnnb1 14 0.64 5.48 0.41
195 INT95872 Localization of Ctnnb1 7 0.74 2.75 0.4
196 INT132128 Positive_regulation of Phosphorylation of Rps6 1 0.49 0.16 0.4
197 INT139976 Regulation of Tp53 7 0.44 6.49 0.39
198 INT251556 Localization of Adam17 2 0.38 2 0.39
199 INT132126 Phosphorylation of Rps6 1 0.80 0.16 0.39
200 INT208559 Negative_regulation of Gene_expression of Shh 8 0.43 1.58 0.38
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