GO:0033089

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Name positive regulation of T cell differentiation in thymus
Categary Process
Go Slim No
Go Link GO:0033089
Unique Molecular Interactions 97
Total Molecular Interactions 129
Total Single Events 893
Pain Genes Associated 12

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of T cell differentiation in thymus. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of T cell differentiation in thymus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT279359 Binding of ADA and TNF 1 0.20 2.61 1.91
2 INT140985 Gli3 Regulation of Ihh 1 0.29 0.85 0.85
3 INT238642 Binding of TNF and Ada 1 0.03 0.86 0.84
4 INT104831 Binding of GLI2 and NFKB1 1 0.08 0 0.8
5 INT231751 Binding of Il2rg and Jak3 1 0.03 1.56 0.67
6 INT149899 Ihh Positive_regulation of Mmp7 1 0.04 1.69 0.65
7 INT149894 Ihh Positive_regulation of Localization of Mmp14 1 0.04 2.06 0.47
8 INT279360 ADA Negative_regulation of Gene_expression of IFNG 1 0.06 0.51 0.44
9 INT116938 Positive_regulation of GLI2 Positive_regulation of MAPK8 1 0.10 0.07 0.41
10 INT116936 Positive_regulation of GLI2 Positive_regulation of JUN 1 0.12 0.07 0.41
11 INT113040 IHH Regulation of Gene_expression of INS 1 0.12 0.37 0.37
12 INT279369 Binding of ADA and Ifx 1 0.29 0.27 0.35
13 INT149897 Ihh Positive_regulation of Mmp14 1 0.03 0.93 0.33
14 INT149896 Ihh Regulation of Gene_expression of Col1a1 1 0.06 0.89 0.33
15 INT149895 Ihh Regulation of Localization of Mmp7 1 0.03 0.98 0.33
16 INT149902 Ihh Positive_regulation of SGCG 1 0.45 0.76 0.32
17 INT149898 Ihh Regulation of Localization of Mmp14 1 0.03 1.29 0.27
18 INT183247 ADA Negative_regulation of ADORA1 1 0.01 0 0.23
19 INT210798 Ihh Positive_regulation of Itgbl1 1 0.34 0 0.23
20 INT104834 Binding of GLI2 and IGKV2OR2-1 1 0.00 0 0.22
21 INT260870 Binding of HLA-E and IL7R 1 0.19 0.5 0.22
22 INT256629 Binding of Ptch1 and Shh 7 0.42 4.22 0.19
23 INT303937 Positive_regulation of Binding of GLI2 and CCL5 1 0.01 0 0.18
24 INT303940 Regulation of Binding of GLI2 and CCL5 1 0.01 0 0.18
25 INT303938 Binding of GLI2 and CCL5 1 0.01 0 0.18
26 INT210795 Ihh Negative_regulation of Itgb1 1 0.30 0 0.17
27 INT303939 TRAP Positive_regulation of Protein_catabolism of GLI2 1 0.01 0 0.16
28 INT303941 CCL2 Positive_regulation of Protein_catabolism of GLI2 1 0.01 0 0.16
29 INT210782 Ihh Negative_regulation of Itgbl1 1 0.31 0 0.16
30 INT210804 Ihh Negative_regulation of Timp4 1 0.32 0 0.16
31 INT104837 IGKV2OR2-1 Negative_regulation of GLI2 1 0.00 0 0.15
32 INT165161 Ihh Positive_regulation of Sostdc1 1 0.58 0.07 0.09
33 INT165160 Regulation of Ihh Positive_regulation of Sostdc1 1 0.23 0.07 0.09
34 INT165158 Positive_regulation of Ihh Positive_regulation of Sostdc1 1 0.42 0.07 0.09
35 INT210788 Ihh Negative_regulation of Coro1a 1 0.02 0 0.08
36 INT270464 Binding of Shh and Smo 1 0.07 1.3 0.08
37 INT210790 Ihh Negative_regulation of Cdkn1c 1 0.30 0 0.08
38 INT290906 Shh Positive_regulation of Egfr 1 0.23 0 0.08
39 INT210787 Ihh Negative_regulation of Nr3c1 1 0.33 0 0.08
40 INT296034 FOXP3 Negative_regulation of Gene_expression of IL7R 1 0.10 0.63 0.08
41 INT298349 HES3 Positive_regulation of Shh 1 0.12 0.14 0.07
42 INT290905 Gene_expression of Shh Positive_regulation of Gene_expression of Angpt1 1 0.14 0 0.06
43 INT343538 TGFB1 Positive_regulation of Gene_expression of GLI2 1 0.08 0.2 0.05
44 INT213563 Binding of Ctnnd2 and Shh 1 0.27 0.09 0.04
45 INT270459 Binding of Shh and Gli1 1 0.02 0.65 0.04
46 INT352014 Shh Positive_regulation of Gene_expression of Pax1 1 0.29 0.07 0.03
47 INT343545 Binding of GLI2 and ROCK1 1 0.07 0.65 0.03
48 INT311655 Shh Positive_regulation of Gene_expression of Fgf8 1 0.31 0.18 0.03
49 INT270462 Shh Positive_regulation of Ccnd1 1 0.10 0.6 0.03
50 INT213559 Binding of Egf and Shh 1 0.17 0.07 0.03
51 INT343544 Negative_regulation of GLI2 Negative_regulation of Gene_expression of PTHLH 1 0.24 0.53 0.03
52 INT290910 Pkm2 Negative_regulation of Shh 1 0.07 0.06 0
53 INT205963 GLI1 Positive_regulation of Negative_regulation of SHH 1 0.22 0.58 0
54 INT314850 Shh Regulation of Atoh7 1 0.45 0.22 0
55 INT158907 Ogt Negative_regulation of Gene_expression of Ada 1 0.44 0 0
56 INT290908 Regulation of Shh Positive_regulation of Ntn1 1 0.12 0 0
57 INT290911 Gene_expression of Shh Positive_regulation of Pkm2 1 0.07 0 0
58 INT290904 Shh Positive_regulation of Prkcg 1 0.26 0.06 0
59 INT290900 Prkcg Regulation of Shh 1 0.23 0 0
60 INT197794 Negative_regulation of Pthlh Regulation of Ihh 1 0.36 1.33 0
61 INT205960 Binding of PTCH1 and SHH 1 0.21 0.71 0
62 INT290944 Shh Positive_regulation of VEGFA 1 0.04 0.05 0
63 INT270461 Shh Regulation of Gene_expression of Ptch1 1 0.48 0.07 0
64 INT207374 Gene_expression of GLI2 Negative_regulation of Gene_expression of Chol1 1 0.04 0 0
65 INT205959 Binding of SHH and SMOX 1 0.12 0.72 0
66 INT343548 GLI2 Positive_regulation of Gene_expression of PTHLH 1 0.28 0.94 0
67 INT104529 Ada Negative_regulation of Positive_regulation of FSCN1 1 0.03 0 0
68 INT270471 Shh Regulation of VEGFA 1 0.39 0.08 0
69 INT290898 Shh Positive_regulation of Nos2 1 0.46 0.05 0
70 INT343549 GLI2 Positive_regulation of GYPA 1 0.05 0.95 0
71 INT104530 Ada Negative_regulation of FSCN1 1 0.03 0 0
72 INT270466 Ptch1 Regulation of Gene_expression of Shh 1 0.48 0.07 0
73 INT312950 Binding of ADA and HBN1 1 0.01 0.49 0
74 INT207336 Gene_expression of GLI2 Negative_regulation of Gene_expression of CYP27A1 1 0.00 0 0
75 INT270460 Shh Positive_regulation of Gene_expression of Angpt1 1 0.04 0.08 0
76 INT270470 Shh Regulation of Gene_expression of VEGFA 1 0.39 0.15 0
77 INT290907 Shh Positive_regulation of Ntn1 1 0.32 0.05 0
78 INT205977 Binding of SHH and Ptch1 1 0.31 0.71 0
79 INT270469 Shh Positive_regulation of VEGFA 1 0.29 0.12 0
80 INT343539 GLI2 Regulation of PTHLH 1 0.15 0.25 0
81 INT270468 Shh Positive_regulation of Gene_expression of VEGFA 1 0.44 0.08 0
82 INT158906 Ogt Negative_regulation of Ada 1 0.33 0 0
83 INT264737 Hes1 Regulation of Shh 1 0.19 0.13 0
84 INT197793 Pthlh Regulation of Ihh 1 0.22 1.32 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of T cell differentiation in thymus. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of T cell differentiation in thymus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT32802 Negative_regulation of Ada 21 0.57 4.03 14.87
2 INT11238 Positive_regulation of ADA 33 0.70 39.7 9.98
3 INT4663 Positive_regulation of Ada 17 0.69 9.48 7.93
4 INT29674 Gene_expression of Ada 16 0.78 4.59 5.69
5 INT30206 Negative_regulation of ADA 17 0.59 10.03 5.63
6 INT68202 Gene_expression of ADA 26 0.68 23.15 5.18
7 INT36256 Regulation of Ada 9 0.62 4.99 5.07
8 INT9767 Negative_regulation of Ada 5 0.55 0.06 5.06
9 INT64170 Gene_expression of GLI2 31 0.46 14.96 3.99
10 INT134590 Localization of ADA 7 0.65 8.43 3.96
11 INT72798 Binding of ADA 12 0.47 7.84 3.39
12 INT19392 Gene_expression of Ada 9 0.77 7.4 3.17
13 INT34604 Binding of Ada 11 0.31 4.15 3.1
14 INT9766 Positive_regulation of Ada 2 0.47 0.4 3.09
15 INT131494 Regulation of ADA 8 0.52 7.37 2.97
16 INT113041 Gene_expression of IHH 9 0.78 5.83 2.87
17 INT81312 Positive_regulation of Gene_expression of Ada 2 0.50 1.58 2.26
18 INT144973 Gene_expression of Shh 9 0.77 4.32 1.96
19 INT61806 Regulation of Negative_regulation of Ada 1 0.30 0.63 1.89
20 INT208561 Gene_expression of Shh 51 0.78 9.57 1.77
21 INT90926 Positive_regulation of GLI2 12 0.45 4.99 1.74
22 INT34605 Localization of Ada 7 0.80 0.13 1.61
23 INT137927 Positive_regulation of Positive_regulation of Ada 1 0.03 1.31 1.47
24 INT30277 Protein_catabolism of Ada 3 0.52 0.9 1.42
25 INT181873 Regulation of Localization of ADA 1 0.07 1.98 1.41
26 INT181961 Gene_expression of IL7R 10 0.75 3.9 1.29
27 INT104839 Negative_regulation of GLI2 8 0.35 2.7 1.24
28 INT140983 Gene_expression of Ihh 7 0.78 2.06 1.15
29 INT253191 Positive_regulation of Gene_expression of Shh 2 0.66 2.57 1.14
30 INT192073 Positive_regulation of Gene_expression of ADA 8 0.47 10.35 1.12
31 INT238636 Regulation of Ada 2 0.15 1.12 1.06
32 INT165530 Positive_regulation of Shh 4 0.69 1.21 1.05
33 INT119674 Localization of GLI2 6 0.52 2.84 0.99
34 INT182322 Negative_regulation of Gene_expression of GLI2 6 0.11 2.37 0.98
35 INT238637 Binding of Ada 2 0.26 1.01 0.94
36 INT64173 Regulation of Gene_expression of GLI2 4 0.37 2.89 0.88
37 INT289474 Regulation of GLI2 2 0.06 1.08 0.87
38 INT68200 Protein_catabolism of Ada 2 0.44 0.68 0.83
39 INT279366 Positive_regulation of Localization of ADA 2 0.42 4.37 0.76
40 INT104840 Binding of GLI2 6 0.08 1.89 0.72
41 INT40605 Negative_regulation of Negative_regulation of Ada 1 0.32 0 0.7
42 INT210028 Protein_catabolism of ADA 1 0.07 0.13 0.62
43 INT113042 Localization of IHH 1 0.70 0.77 0.61
44 INT140984 Regulation of Ihh 5 0.54 2.81 0.56
45 INT206484 Localization of Shh 2 0.75 1.14 0.46
46 INT232798 Positive_regulation of Gene_expression of Shh 7 0.70 1.49 0.44
47 INT143682 Negative_regulation of Gene_expression of Ada 2 0.54 0.28 0.44
48 INT143683 Negative_regulation of Gene_expression of ADA 1 0.09 0.28 0.44
49 INT56363 Regulation of Gene_expression of Ada 1 0.06 0.59 0.42
50 INT208559 Negative_regulation of Gene_expression of Shh 8 0.43 1.58 0.38
51 INT260878 Binding of IL7R 1 0.33 0.87 0.35
52 INT166716 Negative_regulation of Ihh 3 0.43 0.67 0.33
53 INT279365 Regulation of Regulation of ADA 1 0.23 0 0.33
54 INT119675 Positive_regulation of Localization of GLI2 1 0.32 0.43 0.3
55 INT234407 Positive_regulation of Binding of GLI2 2 0.05 1.33 0.28
56 INT232795 Positive_regulation of Shh 2 0.70 3.68 0.26
57 INT149893 Positive_regulation of Gene_expression of Ihh 1 0.69 0.62 0.26
58 INT149892 Gene_expression of Ihh 1 0.77 0.61 0.26
59 INT260876 Negative_regulation of IL7R 1 0.29 0.47 0.24
60 INT303943 Protein_catabolism of GLI2 2 0.11 0 0.22
61 INT183062 Gene_expression of SHH 12 0.65 5.28 0.21
62 INT134477 Negative_regulation of SHH 2 0.37 1.13 0.2
63 INT149888 Localization of Ihh 1 0.75 0.77 0.2
64 INT232799 Regulation of Gene_expression of Shh 3 0.27 1.04 0.16
65 INT182321 Positive_regulation of Gene_expression of GLI2 2 0.28 1.32 0.16
66 INT253177 Negative_regulation of Gene_expression of Shh 2 0.55 0.63 0.16
67 INT278241 Regulation of IHH 2 0.31 1.16 0.14
68 INT253190 Localization of Shh 2 0.77 1.06 0.13
69 INT253183 Negative_regulation of Shh 8 0.55 2.13 0.12
70 INT323226 Negative_regulation of Localization of ADA 1 0.35 3.05 0.1
71 INT110170 Positive_regulation of Positive_regulation of ADA 1 0.49 0.46 0.1
72 INT270442 Transcription of Shh 1 0.53 0.25 0.09
73 INT213515 Binding of Shh 8 0.37 1.92 0.08
74 INT210805 Negative_regulation of IHH 2 0.42 0.74 0.08
75 INT270453 Regulation of Shh 1 0.27 0.83 0.08
76 INT205973 Binding of SHH 3 0.35 1.03 0.07
77 INT168919 Regulation of Regulation of Ihh 1 0.40 0.43 0.07
78 INT256862 Regulation of Shh 1 0.25 0 0.07
79 INT349640 Transcription of IL7R 1 0.26 0 0.07
80 INT349637 Positive_regulation of Transcription of IL7R 1 0.19 0 0.07
81 INT270445 Positive_regulation of Localization of Shh 1 0.44 0.13 0.05
82 INT251811 Positive_regulation of IHH 1 0.29 0.09 0.05
83 INT181793 Positive_regulation of SHH 3 0.67 2.59 0.04
84 INT208560 Negative_regulation of Shh 2 0.59 2.22 0.04
85 INT165149 Positive_regulation of Ihh 1 0.42 0.09 0.04
86 INT253187 Negative_regulation of Transcription of Shh 1 0.41 0.55 0.03
87 INT253181 Transcription of Shh 1 0.68 0.54 0.03
88 INT294470 Transcription of IHH 1 0.16 0.28 0.03
89 INT207371 Positive_regulation of Transcription of GLI2 1 0.03 0.08 0
90 INT322888 Negative_regulation of Ihh 1 0.26 0.45 0
91 INT290918 Negative_regulation of Positive_regulation of Shh 1 0.41 0.25 0
92 INT230972 Positive_regulation of Gene_expression of SHH 1 0.18 0.07 0
93 INT307407 Regulation of Localization of GLI2 1 0.01 0.67 0
94 INT207369 Transcription of GLI2 1 0.05 0.08 0
95 INT290929 Binding of Shh 1 0.31 0.1 0
96 INT290927 Regulation of Positive_regulation of Shh 1 0.23 0 0
97 INT301356 Binding of Ihh 1 0.08 0.06 0
98 INT270449 Negative_regulation of Positive_regulation of Shh 1 0.43 0.24 0
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