GO:0033147

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Name negative regulation of intracellular estrogen receptor signaling pathway
Categary Process
Go Slim No
Go Link GO:0033147
Unique Molecular Interactions 18
Total Molecular Interactions 20
Total Single Events 154
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of intracellular estrogen receptor signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of intracellular estrogen receptor signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT271511 Binding of Phb2 and Glrb 1 0.04 1.7 0.84
2 INT173475 Bcar1 Regulation of Isl1 1 0.01 0 0.47
3 INT335850 Snrpc Negative_regulation of Gene_expression of Isl1 1 0.00 1.51 0.45
4 INT108771 Phb2 Positive_regulation of Crp 1 0.02 0.15 0.32
5 INT335049 PPARA Negative_regulation of Gene_expression of CYP7B1 1 0.27 0 0.26
6 INT108769 Phb2 Positive_regulation of Aldh3a1 1 0.08 0.08 0.19
7 INT247155 Binding of Phb2 and Scarb1 1 0.01 0.33 0
8 INT244856 Lbx1 Regulation of Isl1 1 0.60 0 0
9 INT172838 Binding of ISL1 and T2dm2 1 0.00 2.41 0
10 INT323254 Binding of Ptprv and Isl1 1 0.00 0.6 0
11 INT244860 Lbx1 Negative_regulation of Isl1 1 0.16 0 0
12 INT323253 Binding of Ins1 and Isl1 1 0.00 0.59 0
13 INT323251 Binding of Isl1 and Uchl1 1 0.00 0.6 0
14 INT323252 Binding of H2-Ab1 and Isl1 1 0.00 0.6 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of intracellular estrogen receptor signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of intracellular estrogen receptor signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT203443 Gene_expression of Isl1 27 0.67 11.12 4.65
2 INT200838 Positive_regulation of Isl1 6 0.60 0.73 1.19
3 INT172809 Gene_expression of ISL1 33 0.40 21.63 1.12
4 INT173472 Positive_regulation of Isl1 1 0.03 0.2 0.83
5 INT243779 Negative_regulation of Gene_expression of Isl1 2 0.30 2.62 0.68
6 INT187079 Gene_expression of CYP7B1 2 0.32 1 0.66
7 INT226838 Transcription of Isl1 2 0.28 0.36 0.6
8 INT326496 Regulation of Phb2 1 0.06 1.03 0.52
9 INT187078 Positive_regulation of Gene_expression of CYP7B1 1 0.01 1 0.4
10 INT9065 Positive_regulation of Gene_expression of Phb2 1 0.33 0 0.38
11 INT9063 Gene_expression of Phb2 2 0.45 0 0.37
12 INT17937 Gene_expression of Isl1 4 0.27 0.48 0.36
13 INT172806 Localization of ISL1 4 0.26 2.64 0.29
14 INT78132 Binding of Isl1 1 0.16 0 0.27
15 INT25465 Positive_regulation of ISL1 6 0.15 3.59 0.26
16 INT173797 Negative_regulation of Isl1 3 0.37 0.15 0.26
17 INT173792 Negative_regulation of Negative_regulation of Isl1 1 0.08 0.15 0.26
18 INT205087 Positive_regulation of Gene_expression of ISL1 4 0.26 3.86 0.19
19 INT243778 Binding of Isl1 1 0.26 0 0.19
20 INT98772 Localization of Isl1 2 0.65 0 0.16
21 INT201210 Negative_regulation of ISL1 2 0.02 0.4 0.16
22 INT87960 Regulation of Phb2 1 0.12 0.29 0.14
23 INT98774 Regulation of Localization of Isl1 1 0.08 0 0.13
24 INT207829 Positive_regulation of Localization of ISL1 1 0.02 0.1 0.1
25 INT173473 Positive_regulation of Positive_regulation of Isl1 1 0.02 0.06 0.09
26 INT173470 Positive_regulation of Phosphorylation of Isl1 1 0.02 0 0.09
27 INT173471 Phosphorylation of Isl1 1 0.04 0 0.09
28 INT298237 Regulation of Isl1 1 0.03 0.24 0.06
29 INT352541 Transcription of ISL1 1 0.36 0.2 0.03
30 INT87962 Positive_regulation of Phb2 3 0.20 0 0
31 INT180121 Phosphorylation of Isl1 1 0.27 0 0
32 INT180097 Positive_regulation of Phosphorylation of Isl1 1 0.17 0 0
33 INT352867 Regulation of CYP7B1 1 0.20 0.13 0
34 INT227625 Regulation of ISL1 1 0.05 0.35 0
35 INT243780 Positive_regulation of Gene_expression of Isl1 1 0.35 0 0
36 INT183071 Negative_regulation of Gene_expression of ISL1 1 0.20 0.34 0
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