GO:0033197

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Name response to vitamin E
Categary Process
Go Slim No
Go Link GO:0033197
Unique Molecular Interactions 302
Total Molecular Interactions 455
Total Single Events 4396
Pain Genes Associated 22

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for response to vitamin E. They are ordered first by their pain relevance and then by number of times they were reported for response to vitamin E. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT254001 Binding of Cxcr4 and Mif 1 0.52 14.17 7.18
2 INT83169 Binding of Cck and Lep 7 0.42 1.58 2.78
3 INT278948 LEP Positive_regulation of Gene_expression of PTGER2 1 0.09 4.04 2.69
4 INT253988 Binding of Cd74 and Mif 1 0.36 6.57 2.52
5 INT278937 LEP Positive_regulation of Gene_expression of IL6 1 0.32 3.42 1.97
6 INT83170 Lep Regulation of Cck 5 0.43 0.68 1.96
7 INT89011 Lep Positive_regulation of Insr 1 0.19 2.41 1.57
8 INT315284 PRKG1 Positive_regulation of Nos1 1 0.33 0.85 1.56
9 INT42580 CAT Negative_regulation of POMC 1 0.20 0.42 1.26
10 INT124108 Binding of RYBP and Ccne1 1 0.09 0.34 1.26
11 INT253999 Binding of Cxcl12 and Mif 1 0.41 2.26 1.22
12 INT353338 F2r Positive_regulation of Localization of Mif 1 0.68 1.25 1.16
13 INT69504 Binding of Nos1 and Gatm 1 0.05 0 1.13
14 INT56990 Cat Regulation of Efs 1 0.26 0 1.05
15 INT119914 Olr1714 Negative_regulation of Nos1 1 0.02 0.47 1.01
16 INT117311 HP Positive_regulation of Lep 1 0.00 1.78 1.01
17 INT278962 LEP Positive_regulation of CPOX 1 0.05 1.33 1
18 INT130232 Binding of Cat and Sod1 1 0.35 0.3 0.98
19 INT130231 Positive_regulation of Binding of Cat and Sod1 1 0.46 0.3 0.98
20 INT278940 LEP Positive_regulation of Gene_expression of IL8 1 0.34 1.68 0.96
21 INT40636 Mif Negative_regulation of Pomc 1 0.25 0.07 0.9
22 INT253992 Cxcl12 Positive_regulation of Mif 1 0.46 1.31 0.88
23 INT122350 Ngf Regulation of Hsd3b1 1 0.34 0 0.87
24 INT155761 Binding of Nos1 and Tjp1 1 0.13 1.01 0.82
25 INT155760 Binding of Nos1 and Dlg4 1 0.13 1.01 0.82
26 INT130948 Amt Regulation of Gene_expression of LEP 1 0.00 1.04 0.78
27 INT130949 Amt Regulation of LEP 1 0.00 1.04 0.77
28 INT339495 Tlr4 Positive_regulation of Eif2ak2 1 0.21 0.58 0.77
29 INT90120 Jun Positive_regulation of Gene_expression of Nos1 1 0.38 0.39 0.76
30 INT90117 Jun Regulation of Gene_expression of Nos1 1 0.21 0.39 0.76
31 INT90125 Nfkb1 Regulation of Gene_expression of Nos1 1 0.17 0.39 0.76
32 INT90116 Nfkb1 Positive_regulation of Gene_expression of Nos1 1 0.32 0.39 0.76
33 INT108611 Adra2a Regulation of Gene_expression of Nos1 1 0.10 0 0.75
34 INT278958 LEP Positive_regulation of IL1B 1 0.33 1.91 0.74
35 INT220033 Casp3 Positive_regulation of Gene_expression of Nos1 1 0.05 0.52 0.72
36 INT40703 Mif Negative_regulation of Negative_regulation of POMC 1 0.24 0.49 0.7
37 INT89009 Lep Positive_regulation of Cck 2 0.67 0.43 0.69
38 INT278956 LEP Regulation of Gene_expression of IL8 1 0.30 1.11 0.69
39 INT278968 LEP Regulation of Gene_expression of IL6 1 0.29 1.11 0.69
40 INT253994 Cyp3a23/3a1 Positive_regulation of Localization of Mif 1 0.09 0.96 0.69
41 INT278951 LEP Regulation of Gene_expression of PTGER2 1 0.07 1.11 0.69
42 INT106154 Calca Positive_regulation of Nos1 1 0.29 0.2 0.68
43 INT347962 Cpox Negative_regulation of Positive_regulation of Nos1 1 0.02 0.59 0.67
44 INT278965 LEP Positive_regulation of Gene_expression of NOS2 2 0.29 2.12 0.66
45 INT220032 Nos1 Positive_regulation of Nos3 1 0.32 0.45 0.66
46 INT220035 Nos1 Positive_regulation of Nos2 1 0.29 0.45 0.66
47 INT118824 OPA1 Positive_regulation of Gene_expression of Nos1 2 0.03 0.24 0.65
48 INT78663 Dlst Regulation of Nos1 1 0.19 0.91 0.65
49 INT164990 Mif Positive_regulation of Gene_expression of Grina 1 0.24 0.53 0.6
50 INT349083 Binding of Lep and Rtn1 1 0.09 1.68 0.57
51 INT204087 IL1B Positive_regulation of Gene_expression of LEP 1 0.09 2.6 0.54
52 INT97425 Prkcg Regulation of Regulation of Nos1 1 0.06 0 0.53
53 INT90121 Nos1 Regulation of Fos 1 0.27 0.25 0.49
54 INT162890 Negative_regulation of Binding of LEP and Tnf 1 0.03 0.49 0.48
55 INT162889 Binding of LEP and Tnf 1 0.03 0.49 0.48
56 INT296114 Il4 Regulation of Gene_expression of Arg1 1 0.00 0.65 0.46
57 INT253997 Binding of Cd200r1 and Mif 1 0.03 1.02 0.46
58 INT132509 Binding of LEP and Cck 1 0.13 0.16 0.45
59 INT323880 Binding of BMI1 and LEP 1 0.02 3.97 0.41
60 INT146273 Binding of Nos1 and Rasd1 1 0.34 0.18 0.41
61 INT83171 Cck Regulation of Lep 1 0.30 0.09 0.4
62 INT285725 Binding of IGF1R and INS 1 0.27 0.07 0.4
63 INT97395 Lep Positive_regulation of Stat3 1 0.67 0.42 0.4
64 INT146272 Binding of Nos1 and Nos1ap 1 0.28 0.2 0.39
65 INT143747 Binding of IL6 and LEP 2 0.04 4.05 0.38
66 INT163831 ERBB2 Positive_regulation of CCND1 1 0.03 0.82 0.38
67 INT300488 Binding of CRP and LEP 1 0.46 2.03 0.37
68 INT320591 Ca2 Positive_regulation of Nos1 1 0.07 0.09 0.37
69 INT226785 Angpt2 Positive_regulation of Localization of Lep 1 0.01 1.65 0.36
70 INT278966 MAPK14 Positive_regulation of Gene_expression of LEP 1 0.16 0.62 0.36
71 INT278949 JAK3 Positive_regulation of Gene_expression of LEP 1 0.42 0.63 0.36
72 INT323885 LEP Regulation of Gene_expression of NOS2 1 0.26 1.07 0.35
73 INT72953 Mif Positive_regulation of Localization of Prl 1 0.42 0 0.34
74 INT323870 LEP Regulation of Gene_expression of MMP13 1 0.21 1.76 0.33
75 INT353333 Positive_regulation of F2r Positive_regulation of Localization of Mif 1 0.46 0.26 0.32
76 INT72951 Mif Regulation of Prl 1 0.41 0 0.32
77 INT353334 F2r Positive_regulation of Mif 1 0.68 0 0.32
78 INT78664 Negative_regulation of Nos1 Negative_regulation of Cebpz 1 0.30 0.43 0.32
79 INT304277 CCNE1 Positive_regulation of IL1RN 1 0.00 1.93 0.31
80 INT105873 Ins1 Negative_regulation of Positive_regulation of Lep 1 0.27 0.67 0.31
81 INT278942 LEP Regulation of IL6 1 0.29 0.61 0.31
82 INT278939 LEP Regulation of IL8 1 0.13 0.61 0.31
83 INT304278 CCNE1 Positive_regulation of IL8 1 0.02 1.93 0.31
84 INT304280 CCNE1 Positive_regulation of IL6 1 0.00 1.93 0.31
85 INT353335 F2r Regulation of Positive_regulation of Mif 1 0.27 0.11 0.31
86 INT278969 LEP Regulation of PTGER2 1 0.03 0.6 0.31
87 INT105874 Lep Negative_regulation of Positive_regulation of Ins1 1 0.27 0.67 0.31
88 INT345421 IFNA1 Positive_regulation of Eif2ak2 2 0.03 1.25 0.3
89 INT226989 Lias Regulation of Gene_expression of Lep 1 0.10 0.91 0.3
90 INT354821 Nos2 Positive_regulation of Eif2ak2 1 0.06 0.64 0.3
91 INT278961 IL6 Regulation of Gene_expression of LEP 1 0.29 0.89 0.3
92 INT304497 Mknk1 Positive_regulation of Nos1 1 0.19 0.53 0.3
93 INT304504 Mapk1 Positive_regulation of Nos1 1 0.29 0.93 0.3
94 INT353336 F2r Regulation of Localization of Mif 1 0.23 0.24 0.28
95 INT339494 Eif2ak2 Positive_regulation of Tlr4 1 0.13 0.18 0.28
96 INT72952 Mif Regulation of Localization of Prl 1 0.28 0 0.27
97 INT254000 Regulation of Binding of Cxcr4 and Mif 1 0.29 0.56 0.27
98 INT353330 F2r Positive_regulation of Positive_regulation of Mif 1 0.46 0 0.26
99 INT100531 Cck Positive_regulation of Lep 1 0.70 0.15 0.26
100 INT242763 Olr1746 Negative_regulation of Nos1 1 0.02 0.97 0.26
101 INT228611 Binding of DNMT3B and LEP 1 0.04 0 0.25
102 INT218732 Lep Regulation of Gene_expression of Trh 1 0.19 0.18 0.25
103 INT126227 Hsp90aa1 Positive_regulation of Nos1 1 0.03 0.73 0.25
104 INT125748 Binding of LEP and Gh 1 0.00 0.52 0.24
105 INT92581 IGF1R Positive_regulation of Gene_expression of PTGER2 1 0.09 0.79 0.24
106 INT339509 Tlr4 Regulation of Eif2ak2 1 0.08 0.16 0.23
107 INT339516 Binding of Eif2ak2 and TIRAP 1 0.25 0.19 0.23
108 INT306795 Binding of LEP and SFTPD 1 0.08 1.13 0.23
109 INT120583 Gsta4 Regulation of Cat 1 0.03 0 0.23
110 INT323883 BMI1 Regulation of LEP 1 0.02 2.39 0.23
111 INT339501 Binding of Eif2ak2 and Tlr4 1 0.14 0.19 0.23
112 INT333394 CFD Negative_regulation of Gene_expression of Cat 1 0.03 0.79 0.22
113 INT110653 Lep Regulation of Localization of Cck 1 0.06 0.22 0.22
114 INT269180 LEP Positive_regulation of Localization of TNF 1 0.01 0.99 0.21
115 INT323873 LEP Regulation of Gene_expression of TIMP2 1 0.31 0.63 0.21
116 INT222482 Lep Positive_regulation of Localization of Gh1 1 0.02 1.02 0.2
117 INT217661 LEP Positive_regulation of INS 2 0.25 1.85 0.19
118 INT327814 Rab8a Regulation of Regulation of Lep 1 0.01 0.15 0.19
119 INT327813 Rab8a Regulation of Lep 1 0.01 0.15 0.19
120 INT326737 IL8 Positive_regulation of Gene_expression of ARG1 1 0.38 2.41 0.19
121 INT339503 Tlr2 Positive_regulation of Eif2ak2 1 0.12 0.09 0.19
122 INT339505 Tlr3 Positive_regulation of Eif2ak2 1 0.14 0.09 0.19
123 INT222661 IFNA1 Positive_regulation of Gene_expression of Nos1 1 0.01 0.25 0.18
124 INT326739 IL8 Regulation of Gene_expression of ARG2 1 0.35 0.46 0.17
125 INT226988 Lias Positive_regulation of Localization of Lep 1 0.08 0.3 0.17
126 INT304503 Map2k1 Positive_regulation of Nos1 1 0.07 0.66 0.16
127 INT168941 Irs2 Regulation of Gene_expression of Igf1r 1 0.39 0.91 0.16
128 INT241177 Abl2 Regulation of Cat 1 0.14 0.3 0.15
129 INT92582 IGF1R Positive_regulation of Transcription of PTGER2 1 0.09 0.43 0.15
130 INT339513 Binding of Socs1 and Eif2ak2 1 0.04 0.07 0.15
131 INT304496 Mknk1 Positive_regulation of Gene_expression of Nos1 1 0.19 0.18 0.15
132 INT217667 LEP Negative_regulation of Localization of INS 1 0.15 1.18 0.14
133 INT78662 Dlst Positive_regulation of Gene_expression of Nos1 1 0.20 0.17 0.14
134 INT326733 Negative_regulation of IL8 Negative_regulation of Gene_expression of ARG2 1 0.24 0.33 0.14
135 INT217664 LEP Negative_regulation of INS 1 0.15 1.18 0.14
136 INT323877 LEP Positive_regulation of SOAT1 1 0.20 1.26 0.14
137 INT326735 Negative_regulation of IL8 Negative_regulation of Gene_expression of ARG1 1 0.32 0.33 0.14
138 INT139975 Binding of LEP and Prl 1 0.02 0.49 0.13
139 INT254002 Binding of Cyp3a23/3a1 and Positive_regulation of Gene_expression of Mif 1 0.08 0.56 0.13
140 INT328060 LEP Positive_regulation of FAAH 1 0.06 0.7 0.13
141 INT346714 LEP Regulation of GALP 1 0.06 0.08 0.13
142 INT81179 LEP Regulation of Localization of GH1 1 0.11 0.91 0.12
143 INT150532 LEP Negative_regulation of Adipoq 1 0.00 1.34 0.12
144 INT150533 Positive_regulation of LEP Negative_regulation of Adipoq 1 0.00 1.34 0.12
145 INT164746 Binding of LEP and Adipoq 1 0.07 0.69 0.12
146 INT323871 LEP Regulation of Gene_expression of IGF1 1 0.14 1.19 0.11
147 INT270746 INS Regulation of LEP 1 0.07 0.72 0.11
148 INT294742 Lep Positive_regulation of Localization of Icam1 1 0.15 0.48 0.11
149 INT163817 Lep Positive_regulation of Phosphorylation of Akt1 1 0.33 0.31 0.11
150 INT222472 Lep Positive_regulation of Localization of Cartpt 1 0.05 0 0.11
151 INT304502 Mknk1 Positive_regulation of Phosphorylation of Nos1 1 0.19 0.16 0.11
152 INT203852 Binding of Eif2ak2 and Lna1 1 0.03 0.65 0.1
153 INT186246 Binding of CAT and SCN5A 1 0.03 0.47 0.1
154 INT186245 Binding of AGRP and CAT 1 0.02 0.53 0.1
155 INT323879 LEP Regulation of SOAT1 1 0.15 1.15 0.1
156 INT204086 TNF Positive_regulation of Gene_expression of LEP 1 0.48 0.74 0.1
157 INT123864 Lep Positive_regulation of Positive_regulation of Cck 1 0.45 0.1 0.09
158 INT242324 Lep Regulation of Gene_expression of Ucp1 1 0.58 1.47 0.09
159 INT142418 Lep Positive_regulation of Gene_expression of Ghrl 1 0.48 1.66 0.09
160 INT306794 Binding of LEP and COPD 1 0.15 3.94 0.09
161 INT339500 Negative_regulation of Socs1 Positive_regulation of Eif2ak2 1 0.05 0.31 0.09
162 INT300486 LEP Positive_regulation of ROS1 1 0.15 0.91 0.09
163 INT222425 Mif Regulation of Tlr4 1 0.01 0.24 0.09
164 INT323868 LEP Regulation of Transcription of COL1A2 1 0.10 0.98 0.09
165 INT185279 Binding of CCND1 and CDK4 4 0.13 2.05 0.08
166 INT185278 Binding of CCND1 and CDK6 3 0.13 1.62 0.08
167 INT222545 Lep Negative_regulation of Nmb 1 0.04 0.52 0.08
168 INT123866 Lep Negative_regulation of Olfr544 1 0.00 0.09 0.08
169 INT332287 LEP Positive_regulation of Phosphorylation of IRS1 1 0.20 1.48 0.08
170 INT323881 BMI1 Regulation of Gene_expression of LEP 1 0.03 1.09 0.08
171 INT323876 LEP Regulation of COL1A2 1 0.10 0.86 0.08
172 INT222514 Mif Regulation of Localization of Il6 1 0.04 0.23 0.08
173 INT294743 Lep Positive_regulation of Transcription of Il6 1 0.18 0.42 0.07
174 INT294740 Lep Positive_regulation of Transcription of Ccl2 1 0.08 0.42 0.07
175 INT166919 Binding of CAT and GSTK1 1 0.09 0.16 0.07
176 INT323872 LEP Positive_regulation of Gene_expression of IGF1 1 0.35 0.77 0.07
177 INT215693 Trib3 Regulation of Gene_expression of Ccnd1 1 0.00 0.09 0.07
178 INT227353 Binding of Cat and Mpo 1 0.18 0.56 0.07
179 INT281879 Cat Negative_regulation of Fig4 1 0.01 0.96 0.06
180 INT229419 Atp6v0a2 Regulation of Cat 1 0.01 1.73 0.06
181 INT253377 Lep Negative_regulation of Phosphorylation of Prkaa2 1 0.24 1.24 0.06
182 INT234619 IGF1 Regulation of IGF1R 1 0.11 0.39 0.05
183 INT323878 Binding of LEP and MMP13 1 0.17 0.77 0.05
184 INT267152 Binding of LEP and DDX12P 1 0.00 0.69 0.05
185 INT234624 Binding of IGF1 and IGF1R 1 0.09 0.39 0.05
186 INT267157 LEP Positive_regulation of ADIPOQ 1 0.10 0.51 0.05
187 INT234620 Regulation of Binding of IGF1 and IGF1R 1 0.07 0.39 0.05
188 INT327821 GPRC6A Regulation of Gene_expression of Lep 1 0.00 0.5 0.05
189 INT353341 F2r Positive_regulation of Negative_regulation of Mif 1 0.49 0 0.05
190 INT327822 INCENP Regulation of Gene_expression of Lep 1 0.00 0.5 0.05
191 INT267153 Binding of LEP and SUGT1 1 0.02 0.69 0.05
192 INT253376 Lep Regulation of Mtor 1 0.17 0.08 0.04
193 INT332684 Binding of Edn1 and Lep 1 0.09 1.11 0.04
194 INT207702 CCND1 Regulation of MSMB 1 0.22 0.69 0.04
195 INT253363 Lep Regulation of Prkaa2 1 0.15 0.08 0.04
196 INT222534 Gnrh1 Positive_regulation of Localization of Lep 1 0.07 0 0.04
197 INT227352 Binding of Cat and Ros1 1 0.04 1.06 0.04
198 INT252767 CAT Regulation of Gpx1 1 0.00 0.25 0.04
199 INT249046 Binding of LEP and ARID1B 1 0.01 1.3 0.03
200 INT231438 LEP Positive_regulation of Negative_regulation of NOS3 1 0.09 0.32 0.03

Single Events

The table below shows the top 100 pain related interactions that have been reported for response to vitamin E. They are ordered first by their pain relevance and then by number of times they were reported in response to vitamin E. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT74058 Gene_expression of Nos1 260 0.78 80.04 95.71
2 INT49028 Positive_regulation of Nos1 102 0.70 34.73 51.05
3 INT17881 Gene_expression of LEP 278 0.78 221.61 48.31
4 INT64558 Negative_regulation of Nos1 88 0.58 26.76 36.78
5 INT116737 Localization of Mif 63 0.81 52.97 28.11
6 INT74688 Regulation of Nos1 55 0.62 22.16 25.3
7 INT76123 Gene_expression of Lep 193 0.78 94.17 22.76
8 INT74059 Positive_regulation of Gene_expression of Nos1 55 0.70 11.5 21.39
9 INT12951 Negative_regulation of Cat 126 0.57 64.39 20.61
10 INT40750 Gene_expression of Mif 61 0.78 34.59 20.28
11 INT82434 Positive_regulation of LEP 117 0.70 95.45 20.22
12 INT9246 Positive_regulation of Cat 113 0.70 52.73 18.04
13 INT62681 Negative_regulation of LEP 93 0.59 66.97 15.77
14 INT12950 Gene_expression of Cat 85 0.75 35.94 15.76
15 INT116736 Positive_regulation of Mif 40 0.70 31.93 15.37
16 INT75908 Regulation of LEP 77 0.60 60.16 15.19
17 INT32802 Negative_regulation of Ada 21 0.57 4.03 14.87
18 INT74098 Negative_regulation of Gene_expression of Nos1 36 0.59 16.25 14.82
19 INT73641 Regulation of Lep 45 0.62 26.2 12.59
20 INT72949 Binding of Mif 31 0.46 23.12 11.65
21 INT126743 Positive_regulation of Gene_expression of LEP 61 0.66 50.02 11.17
22 INT82079 Positive_regulation of Lep 79 0.70 40 11.07
23 INT22132 Positive_regulation of CAT 41 0.67 18.64 10.67
24 INT90114 Regulation of Gene_expression of Nos1 18 0.62 6.38 10.52
25 INT82078 Negative_regulation of Lep 54 0.59 20.47 9.38
26 INT82082 Localization of Lep 63 0.81 26.41 8.56
27 INT75907 Binding of LEP 53 0.46 46.65 8.44
28 INT84672 Negative_regulation of Positive_regulation of Nos1 12 0.48 3.76 8.27
29 INT4663 Positive_regulation of Ada 17 0.69 9.48 7.93
30 INT4228 Gene_expression of CAT 50 0.75 20.62 7.18
31 INT612 Positive_regulation of Orm1 15 0.68 5.24 6.73
32 INT517 Regulation of Mif 16 0.62 5.43 6.55
33 INT69499 Binding of Nos1 15 0.36 2.56 6.23
34 INT93658 Transcription of Nos1 16 0.72 6.85 6.16
35 INT516 Negative_regulation of Mif 13 0.59 6.69 6.08
36 INT75501 Gene_expression of CCND1 90 0.76 60.86 5.93
37 INT146594 Negative_regulation of Gene_expression of LEP 25 0.42 18.88 5.71
38 INT29674 Gene_expression of Ada 16 0.78 4.59 5.69
39 INT84673 Localization of Nos1 19 0.80 5.01 5.62
40 INT9325 Gene_expression of Igf1r 14 0.77 8.74 5.48
41 INT65356 Localization of LEP 46 0.79 41.17 5.43
42 INT35536 Negative_regulation of CAT 26 0.57 14.39 5.38
43 INT38366 Regulation of Cat 45 0.62 23.45 5.34
44 INT36256 Regulation of Ada 9 0.62 4.99 5.07
45 INT174339 Positive_regulation of Localization of Mif 7 0.61 8.27 4.95
46 INT97391 Binding of Lep 18 0.48 8.97 4.47
47 INT116738 Positive_regulation of Gene_expression of Mif 14 0.68 10.99 3.8
48 INT119606 Regulation of Gene_expression of LEP 17 0.45 17.96 3.75
49 INT112340 Gene_expression of Cyp11a1 11 0.77 5.19 3.7
50 INT93399 Gene_expression of Ccnd1 38 0.58 21 3.65
51 INT31580 Negative_regulation of Cyp11a1 14 0.57 3.48 3.61
52 INT82077 Positive_regulation of Gene_expression of Lep 32 0.70 17.9 3.5
53 INT134875 Phosphorylation of Nos1 5 0.70 1.21 3.44
54 INT75500 Negative_regulation of Gene_expression of CCND1 21 0.57 11.59 3.24
55 INT12948 Positive_regulation of Gene_expression of Cat 17 0.67 6.46 3.12
56 INT34604 Binding of Ada 11 0.31 4.15 3.1
57 INT64386 Binding of Cyp11a1 13 0.46 5.09 3.01
58 INT90875 Negative_regulation of CCND1 31 0.42 26.22 2.66
59 INT97443 Positive_regulation of Positive_regulation of LEP 13 0.50 11.91 2.65
60 INT108608 Positive_regulation of Positive_regulation of Nos1 8 0.49 1.66 2.58
61 INT136850 Positive_regulation of Arg1 10 0.50 6.96 2.47
62 INT103487 Positive_regulation of Positive_regulation of Lep 9 0.67 4.08 2.38
63 INT22129 Positive_regulation of Gene_expression of CAT 11 0.67 4.23 2.37
64 INT93396 Positive_regulation of Gene_expression of Ccnd1 13 0.52 8.59 2.26
65 INT81312 Positive_regulation of Gene_expression of Ada 2 0.50 1.58 2.26
66 INT203839 Positive_regulation of Eif2ak2 18 0.32 4.36 2.22
67 INT147417 Positive_regulation of Gene_expression of Igf1r 3 0.46 1.69 2.2
68 INT281928 Gene_expression of ARG2 3 0.77 63.17 2.14
69 INT82081 Regulation of Gene_expression of Lep 11 0.53 7.78 2.12
70 INT93398 Negative_regulation of Gene_expression of Ccnd1 5 0.44 2.61 2.12
71 INT58287 Gene_expression of Orm1 3 0.66 1.17 2.12
72 INT104402 Positive_regulation of CCND1 15 0.70 11.77 2.08
73 INT83392 Transcription of Lep 6 0.54 5.07 2.04
74 INT9336 Negative_regulation of Gene_expression of Igf1r 4 0.42 3.53 1.92
75 INT244704 Gene_expression of ARG1 65 0.75 37.74 1.9
76 INT61806 Regulation of Negative_regulation of Ada 1 0.30 0.63 1.89
77 INT122346 Gene_expression of Hsd3b1 1 0.75 0 1.78
78 INT82083 Negative_regulation of Gene_expression of Lep 12 0.56 8.07 1.75
79 INT36581 Binding of Orm1 6 0.48 0.47 1.73
80 INT64559 Positive_regulation of Negative_regulation of Nos1 2 0.41 1.58 1.68
81 INT97418 Regulation of Regulation of Nos1 2 0.41 0.94 1.68
82 INT112339 Localization of Cyp11a1 2 0.71 0.94 1.68
83 INT44149 Regulation of Gene_expression of Mif 6 0.54 2.45 1.63
84 INT34605 Localization of Ada 7 0.80 0.13 1.61
85 INT353326 Negative_regulation of Localization of Mif 1 0.45 1.28 1.59
86 INT137927 Positive_regulation of Positive_regulation of Ada 1 0.03 1.31 1.47
87 INT30277 Protein_catabolism of Ada 3 0.52 0.9 1.42
88 INT10570 Positive_regulation of Cyp11a1 9 0.47 2.67 1.4
89 INT49128 Gene_expression of IGF1R 35 0.63 23.48 1.39
90 INT122345 Positive_regulation of Gene_expression of Hsd3b1 1 0.49 0 1.34
91 INT115938 Negative_regulation of Negative_regulation of Nos1 2 0.36 0.27 1.31
92 INT253987 Regulation of Localization of Mif 3 0.43 1.65 1.27
93 INT9323 Transcription of Igf1r 2 0.63 1.08 1.23
94 INT91122 Localization of CAT 6 0.78 4.13 1.19
95 INT121368 Transcription of Mif 5 0.72 2.71 1.15
96 INT12952 Negative_regulation of Gene_expression of Cat 16 0.57 7.44 1.14
97 INT82084 Positive_regulation of Localization of Lep 11 0.70 4.65 1.11
98 INT147416 Positive_regulation of Transcription of Igf1r 1 0.46 0.72 1.1
99 INT147415 Positive_regulation of Igf1r 2 0.43 0.97 1.09
100 INT616 Regulation of Orm1 4 0.38 1.72 1.08
101 INT125356 Negative_regulation of Negative_regulation of Cat 4 0.42 2.66 1.06
102 INT108609 Regulation of Localization of Nos1 3 0.45 0 1.06
103 INT122347 Transcription of Hsd3b1 1 0.52 0 0.99
104 INT156727 Gene_expression of Arg1 4 0.44 2.1 0.97
105 INT12945 Negative_regulation of Positive_regulation of Cat 3 0.41 2.61 0.97
106 INT53682 Regulation of Gene_expression of CAT 2 0.60 0.36 0.96
107 INT10578 Transcription of Cyp11a1 3 0.53 0.84 0.93
108 INT134879 Negative_regulation of Phosphorylation of Nos1 1 0.50 0.27 0.93
109 INT55052 Binding of Cat 10 0.36 5.46 0.92
110 INT66314 Negative_regulation of Positive_regulation of CAT 4 0.42 0.8 0.91
111 INT142919 Regulation of Gene_expression of Cat 2 0.32 0.33 0.89
112 INT93747 Localization of Cat 9 0.56 4.25 0.88
113 INT163280 Negative_regulation of Phosphorylation of CCND1 6 0.19 3.92 0.87
114 INT130188 Positive_regulation of Negative_regulation of Cat 5 0.45 2.26 0.86
115 INT117308 Negative_regulation of Localization of Lep 3 0.59 2.16 0.86
116 INT339476 Regulation of Eif2ak2 1 0.28 0.57 0.86
117 INT121906 Positive_regulation of Gene_expression of Orm1 1 0.46 0.08 0.84
118 INT326427 Gene_expression of Eif2ak2 2 0.36 1.32 0.83
119 INT163289 Phosphorylation of CCND1 7 0.36 4.81 0.81
120 INT353328 Regulation of Positive_regulation of Mif 1 0.40 0.89 0.81
121 INT114714 Binding of IGF1R 8 0.36 5.26 0.78
122 INT82080 Regulation of Localization of Lep 2 0.45 1.36 0.76
123 INT156533 Transcription of LEP 9 0.69 4.35 0.74
124 INT9928 Negative_regulation of Orm1 3 0.25 1.21 0.73
125 INT284453 Positive_regulation of Positive_regulation of Eif2ak2 2 0.32 1.23 0.71
126 INT89801 Positive_regulation of Positive_regulation of Cat 2 0.49 0.21 0.71
127 INT40605 Negative_regulation of Negative_regulation of Ada 1 0.32 0 0.7
128 INT97192 Regulation of Transcription of Nos1 1 0.55 1.94 0.68
129 INT353322 Negative_regulation of Positive_regulation of Mif 1 0.38 0.35 0.66
130 INT44148 Negative_regulation of Gene_expression of Mif 6 0.41 0.95 0.64
131 INT107417 Regulation of CAT 8 0.60 2.4 0.61
132 INT83391 Negative_regulation of Transcription of Lep 1 0.43 0.34 0.6
133 INT58987 Positive_regulation of Ccne1 1 0.49 0 0.59
134 INT58988 Positive_regulation of Gene_expression of Ccne1 1 0.67 0 0.59
135 INT128498 Regulation of CCND1 17 0.39 12.51 0.58
136 INT58989 Gene_expression of Ccne1 2 0.75 0.79 0.58
137 INT306798 Protein_catabolism of LEP 1 0.65 2.45 0.58
138 INT130387 Binding of CAT 4 0.36 2.39 0.55
139 INT145859 Regulation of Gene_expression of Igf1r 1 0.59 1.58 0.55
140 INT112279 Regulation of Positive_regulation of Nos1 3 0.39 1.07 0.54
141 INT326769 Regulation of Gene_expression of ARG2 1 0.61 9.7 0.54
142 INT146802 Positive_regulation of Ccnd1 4 0.38 1.37 0.53
143 INT75498 Positive_regulation of Gene_expression of CCND1 21 0.68 19.4 0.51
144 INT339468 Negative_regulation of Eif2ak2 1 0.20 0.21 0.51
145 INT258835 Localization of Ccnd1 3 0.53 2.7 0.5
146 INT281922 Positive_regulation of Gene_expression of ARG2 2 0.69 10.45 0.5
147 INT110165 Negative_regulation of Arg1 8 0.38 3.21 0.48
148 INT146522 Negative_regulation of Positive_regulation of CCND1 3 0.30 2.04 0.48
149 INT93400 Negative_regulation of Ccnd1 4 0.33 0.77 0.47
150 INT82819 Negative_regulation of Negative_regulation of LEP 3 0.56 2.22 0.46
151 INT122348 Regulation of Hsd3b1 1 0.60 0 0.46
152 INT158643 Negative_regulation of Negative_regulation of CCND1 2 0.31 2.43 0.45
153 INT68725 Regulation of Cyp11a1 6 0.19 2.62 0.44
154 INT197674 Positive_regulation of Gene_expression of Arg1 2 0.33 0.63 0.44
155 INT121113 Protein_catabolism of Cyp11a1 2 0.65 0.37 0.44
156 INT326428 Positive_regulation of Gene_expression of Eif2ak2 2 0.32 0.75 0.43
157 INT136205 Positive_regulation of Regulation of Cat 1 0.38 0.51 0.43
158 INT326766 Positive_regulation of Gene_expression of ARG1 12 0.67 8.32 0.42
159 INT339469 Negative_regulation of Positive_regulation of Eif2ak2 1 0.20 0.4 0.42
160 INT56363 Regulation of Gene_expression of Ada 1 0.06 0.59 0.42
161 INT187726 Positive_regulation of Localization of LEP 5 0.50 5.31 0.41
162 INT339484 Phosphorylation of Eif2ak2 1 0.38 0.46 0.41
163 INT296112 Positive_regulation of Positive_regulation of Arg1 1 0.05 0.55 0.4
164 INT168940 Phosphorylation of Igf1r 1 0.77 2.18 0.38
165 INT116735 Positive_regulation of Positive_regulation of Mif 1 0.70 0.61 0.38
166 INT104414 Negative_regulation of Transcription of Nos1 1 0.42 0.96 0.38
167 INT136851 Regulation of Arg1 7 0.38 3.05 0.37
168 INT48336 Negative_regulation of ARG2 4 0.58 3.82 0.36
169 INT39333 Negative_regulation of Positive_regulation of Orm1 1 0.09 0.4 0.36
170 INT84981 Negative_regulation of Gene_expression of CAT 3 0.41 0.35 0.35
171 INT253977 Positive_regulation of Binding of Mif 1 0.48 0.97 0.32
172 INT304298 Positive_regulation of CCNE1 2 0.46 2.95 0.31
173 INT27399 Protein_catabolism of Arg1 1 0.64 0 0.31
174 INT156534 Positive_regulation of Transcription of LEP 1 0.14 0.34 0.3
175 INT120320 Positive_regulation of Transcription of Nos1 3 0.46 0.58 0.29
176 INT141781 Positive_regulation of Negative_regulation of LEP 1 0.46 0.37 0.29
177 INT107757 Regulation of Negative_regulation of Nos1 2 0.39 0 0.27
178 INT326773 Positive_regulation of ARG2 1 0.69 1.89 0.27
179 INT186057 Binding of CCND1 8 0.31 5.92 0.26
180 INT112278 Positive_regulation of Regulation of Nos1 4 0.38 0.99 0.25
181 INT117760 Regulation of Gene_expression of Cyp11a1 2 0.42 0.36 0.25
182 INT113989 Regulation of Gene_expression of CCND1 11 0.44 7.57 0.24
183 INT121366 Regulation of Transcription of Mif 1 0.02 0.61 0.24
184 INT121367 Negative_regulation of Transcription of Mif 1 0.02 0.59 0.24
185 INT203828 Binding of Eif2ak2 1 0.22 0.71 0.24
186 INT150977 Regulation of Regulation of LEP 3 0.37 2.07 0.23
187 INT314003 Negative_regulation of Positive_regulation of Arg1 1 0.13 0.63 0.23
188 INT58442 Transcription of Cat 3 0.67 0.28 0.22
189 INT142417 Positive_regulation of Transcription of Lep 2 0.52 2.63 0.22
190 INT105900 Regulation of Binding of Nos1 1 0.35 0.52 0.22
191 INT192958 Negative_regulation of IGF1R 8 0.30 6.35 0.21
192 INT258055 Positive_regulation of ARG1 7 0.49 3.45 0.19
193 INT146801 Regulation of Ccnd1 5 0.34 2.4 0.19
194 INT168938 Negative_regulation of Phosphorylation of Igf1r 1 0.40 1.1 0.19
195 INT42569 Binding of Ccne1 1 0.21 0.38 0.19
196 INT68735 Binding of Arg2 2 0.05 0.22 0.17
197 INT163816 Phosphorylation of Lep 2 0.63 2.2 0.17
198 INT165802 Phosphorylation of Eif2ak2 2 0.80 2.71 0.17
199 INT10575 Positive_regulation of Transcription of Cyp11a1 1 0.05 0 0.17
200 INT55051 Negative_regulation of Binding of Cat 2 0.35 0.61 0.16
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