GO:0033211

From wiki-pain
Jump to: navigation, search
Name adiponectin-mediated signaling pathway
Categary Process
Go Slim No
Go Link GO:0033211
Unique Molecular Interactions 135
Total Molecular Interactions 171
Total Single Events 1240
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for adiponectin-mediated signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported for adiponectin-mediated signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT83428 Binding of ADIPOQ and FRTS 3 0.18 2.02 1.19
2 INT255336 Csnk2b Regulation of Phosphorylation of Nav1 1 0.10 0 1.03
3 INT255330 Nav1 Regulation of Phosphorylation of Csnk2b 1 0.10 0 0.97
4 INT240619 Binding of CRP and ADIPOQ 8 0.18 10.74 0.78
5 INT255375 AIS Regulation of Negative_regulation of Csnk2b 1 0.02 0 0.69
6 INT311466 Binding of Acsl1 and Il1 1 0.00 2.46 0.63
7 INT311467 Binding of Crp and Acsl1 1 0.00 2.31 0.61
8 INT83424 Binding of CD40LG and ADIPOQ 2 0.13 1 0.59
9 INT83426 ADIPOQ Negative_regulation of Binding of CD40LG 2 0.21 1 0.59
10 INT255379 Csnk2b Positive_regulation of Positive_regulation of AIS 1 0.02 0 0.57
11 INT310531 IL6 Regulation of Regulation of ADIPOQ 1 0.19 0.73 0.52
12 INT255331 Csnk2b Regulation of Binding of Nav1 1 0.05 0 0.43
13 INT83423 ADIPOQ Negative_regulation of Binding of IGHG3 1 0.02 0.31 0.42
14 INT240618 Binding of INS and ADIPOQ 3 0.17 2.54 0.4
15 INT296945 ADIPOQ Negative_regulation of TNF 1 0.03 1.13 0.4
16 INT255374 Csnk2b Positive_regulation of AIS 1 0.02 0.09 0.39
17 INT240617 Binding of APOB and ADIPOQ 1 0.04 3.62 0.38
18 INT240616 Binding of SHBG and ADIPOQ 1 0.31 4.43 0.37
19 INT207184 Binding of Adipoq and Lep 1 0.25 2.45 0.33
20 INT255322 Binding of Dpep1 and Csnk2b 1 0.01 0 0.29
21 INT240626 Binding of ADIPOQ and Hdlcl1 1 0.02 3.27 0.28
22 INT334390 ADIPOQ Positive_regulation of Localization of INS 1 0.09 1.3 0.23
23 INT179492 Binding of Ins1 and Adipoq 1 0.16 1.16 0.23
24 INT249760 Positive_regulation of Cnr1 Negative_regulation of Gene_expression of Adipoq 1 0.20 0.81 0.22
25 INT255329 Csnk2b Regulation of Binding of Nrcam 1 0.02 0 0.22
26 INT255316 Csnk2b Regulation of Binding of Dpep1 1 0.01 0 0.22
27 INT260397 Positive_regulation of Hmox1 Positive_regulation of Gene_expression of Adipoq 1 0.37 0.78 0.22
28 INT242996 Adipoq Negative_regulation of Transcription of Cd68 1 0.22 0.6 0.21
29 INT242994 Adipoq Negative_regulation of Spp1 1 0.19 0.59 0.21
30 INT332304 Binding of Il6 and Adipoq 1 0.03 0.4 0.2
31 INT145886 Binding of CXCL1 and Adipoq 1 0.00 0.77 0.2
32 INT352518 Binding of FAT1 and Adipoq 1 0.01 2.79 0.2
33 INT217665 ADIPOQ Positive_regulation of INS 2 0.06 1.8 0.19
34 INT260394 Positive_regulation of Hmox1 Positive_regulation of Adipoq 1 0.37 0.78 0.19
35 INT334394 ADIPOQ Negative_regulation of Gene_expression of Tnf 1 0.37 1.06 0.18
36 INT207186 Binding of Adipoq and Bmi1 1 0.01 1.65 0.18
37 INT228168 Adipoq Positive_regulation of Prkag1 2 0.05 1.08 0.17
38 INT116268 Binding of Myc and Acsl1 1 0.08 0.19 0.16
39 INT240622 Binding of ADIPOQ and Etv3 1 0.04 1.32 0.15
40 INT157275 Binding of PRKAA1 and Adipoq 1 0.01 1.13 0.15
41 INT255376 Binding of Csnk2b and AIS 1 0.02 0 0.14
42 INT157273 Adipoq Positive_regulation of PRKAA1 1 0.03 1.16 0.14
43 INT270663 Adipoq Positive_regulation of Il6 1 0.02 1.05 0.12
44 INT179493 Adipoq Positive_regulation of Ins1 1 0.20 0.99 0.12
45 INT270669 Adipoq Positive_regulation of IL8 1 0.01 1.06 0.12
46 INT150532 LEP Negative_regulation of Adipoq 1 0.00 1.34 0.12
47 INT150533 Positive_regulation of LEP Negative_regulation of Adipoq 1 0.00 1.34 0.12
48 INT270665 Adipoq Positive_regulation of Ccl2 1 0.07 1.06 0.12
49 INT164746 Binding of LEP and Adipoq 1 0.07 0.69 0.12
50 INT228175 RNU1-1 Regulation of Adipoq 1 0.11 0.78 0.12
51 INT257467 Fat1 Regulation of Gene_expression of Adipoq 1 0.08 0.56 0.11
52 INT240624 Binding of ADIPOQ and Hdl1 1 0.02 0.85 0.1
53 INT262996 ADIPOQ Regulation of INS 1 0.13 1.25 0.1
54 INT310275 Negative_regulation of Binding of Adipoq and Ins1 1 0.19 1.14 0.09
55 INT157276 PPARG Positive_regulation of Adipoq 1 0.29 1.09 0.09
56 INT157274 Adipoq Positive_regulation of ADIPOR1 1 0.00 1.2 0.09
57 INT310274 Binding of Adipoq and Ins1 1 0.21 1.14 0.09
58 INT228174 RNU1-1 Positive_regulation of Gene_expression of Adipoq 1 0.12 0.55 0.08
59 INT157271 Adipor1 Positive_regulation of PRKAA1 1 0.01 0.89 0.08
60 INT257466 Psd Negative_regulation of Gene_expression of Adipoq 1 0.22 0.66 0.08
61 INT267154 ADIPOQ Regulation of Positive_regulation of SUGT1 1 0.03 1.18 0.08
62 INT301645 Binding of Alb and Slc27a1 1 0.02 0.38 0.08
63 INT157268 Adipor1 Positive_regulation of Adipor2 1 0.01 0.89 0.08
64 INT301614 Binding of Slc27a1 and Cd36 1 0.09 0.38 0.08
65 INT352517 Binding of INS and Adipoq 1 0.09 1.32 0.07
66 INT262997 Binding of HSD11B1 and ADIPOQ 1 0.54 2.82 0.07
67 INT157272 Adipor1 Positive_regulation of APRT 1 0.12 0.88 0.07
68 INT260392 Hmox1 Positive_regulation of Adipoq 1 0.32 0.65 0.07
69 INT336380 Gene_expression of Adipoq Positive_regulation of Ppara 1 0.06 1.77 0.07
70 INT140813 Binding of Retn and Adipoq 1 0.03 1.18 0.06
71 INT200889 Acsl1 Positive_regulation of Mapk14 1 0.01 0.09 0.05
72 INT267157 LEP Positive_regulation of ADIPOQ 1 0.10 0.51 0.05
73 INT200890 Acsl1 Positive_regulation of Mapk1 1 0.03 0.09 0.05
74 INT217666 ADIPOQ Regulation of Gene_expression of INS 1 0.03 1.99 0.05
75 INT228169 Gm2733 Regulation of Adipoq 1 0.00 0.51 0.05
76 INT335133 PPARA Positive_regulation of Slc27a1 1 0.10 0.14 0.04
77 INT335127 PPARA Regulation of Slc27a1 1 0.13 0.13 0.04
78 INT228591 Adipoq Positive_regulation of Phosphorylation of Prkaa2 1 0.31 0.61 0.04
79 INT236590 Binding of Adipoq and Ncoa2 1 0.15 0.2 0.03
80 INT236587 Binding of Adipoq and Ncoa1 1 0.17 0.2 0.03
81 INT133489 CREB1 Positive_regulation of Csnk2b 1 0.08 0.42 0.03
82 INT314370 Adipoq Positive_regulation of Tnfrsf11a 1 0.04 1.26 0.03
83 INT133490 AKT1 Positive_regulation of Csnk2b 1 0.02 0.42 0.03
84 INT236592 Positive_regulation of Binding of Adipoq and Ncoa2 1 0.19 0.2 0.03
85 INT133491 CREB1 Positive_regulation of Phosphorylation of Csnk2b 1 0.08 0.42 0.03
86 INT225485 Binding of Acsl1 and Ncoa6 1 0.01 0 0
87 INT225479 Binding of Parp1 and Acsl1 1 0.00 0 0
88 INT227305 Zbp1 Regulation of Gene_expression of Adipoq 1 0.21 1.27 0
89 INT204323 Binding of ADIPOQ and Negative_regulation of Gene_expression of ROS1 1 0.08 0.12 0
90 INT352516 Binding of POMT1 and Adipoq 1 0.01 0.4 0
91 INT225480 Binding of Prkdc and Acsl1 1 0.00 0 0
92 INT204322 Binding of ADIPOQ and Positive_regulation of Gene_expression of PPARGC1A 1 0.30 0.07 0
93 INT225486 Rbm39 Positive_regulation of Acsl1 1 0.00 0 0
94 INT225642 Binding of XRCC5 and Acsl1 1 0.01 0 0
95 INT301636 Slc27a1 Positive_regulation of Fabp4 1 0.01 0 0
96 INT260395 Positive_regulation of Adipoq Negative_regulation of Gene_expression of Hmox1 1 0.34 1.4 0
97 INT225483 Binding of Acsl1 and D0Nrs1 1 0.00 0 0
98 INT225643 Binding of TARBP2 and Acsl1 1 0.00 0 0
99 INT140814 Adipoq Regulation of Retn 1 0.03 0.8 0
100 INT225487 Acsl1 Positive_regulation of D0Nrs1 1 0.00 0 0
101 INT227302 Zbp1 Regulation of Transcription of Adipoq 1 0.09 1.27 0
102 INT313502 Binding of ALOX5AP and ADIPOQ 1 0.05 0.44 0
103 INT350254 Slc12a6 Regulation of Gene_expression of Adipoq 1 0.02 0.63 0
104 INT197915 Des Positive_regulation of Adipoq 1 0.07 0 0
105 INT332943 Binding of SNRNP70 and Adipoq 1 0.00 1.35 0
106 INT353062 HSD11B1 Regulation of Gene_expression of ADIPOQ 1 0.13 5.03 0
107 INT227796 Binding of Acsl1 and Nos3 1 0.16 1.16 0
108 INT301624 Slc27a1 Positive_regulation of fa 1 0.03 0 0
109 INT325283 Negative_regulation of MCL1 Positive_regulation of Gene_expression of ADIPOQ 1 0.14 1.53 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for adiponectin-mediated signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported in adiponectin-mediated signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT133478 Phosphorylation of Csnk2b 29 0.37 1.19 18.73
2 INT117500 Gene_expression of Adipoq 90 0.74 67.79 16.58
3 INT26975 Gene_expression of Adipoq 113 0.75 106.71 14.46
4 INT117502 Positive_regulation of Adipoq 70 0.63 40.43 12.03
5 INT125136 Regulation of Adipoq 24 0.56 16.82 7.23
6 INT137454 Gene_expression of ADIPOQ 88 0.78 85.32 6.2
7 INT146043 Positive_regulation of Gene_expression of Adipoq 39 0.67 29.93 6.12
8 INT117499 Negative_regulation of Adipoq 28 0.56 24.15 5.07
9 INT83431 Binding of ADIPOQ 35 0.48 33.63 3.83
10 INT83433 Positive_regulation of ADIPOQ 40 0.69 34 3.67
11 INT75869 Gene_expression of Acsl1 24 0.45 27.76 3.66
12 INT28021 Positive_regulation of Adipoq 42 0.67 30.79 3.58
13 INT117501 Positive_regulation of Gene_expression of Adipoq 24 0.63 12.99 3.1
14 INT204340 Localization of ADIPOQ 20 0.75 25.18 2.64
15 INT255369 Regulation of Phosphorylation of Csnk2b 1 0.20 0 2.63
16 INT26974 Negative_regulation of Adipoq 27 0.52 26.01 2.59
17 INT111451 Regulation of ADIPOQ 24 0.56 18.81 2.47
18 INT255372 Negative_regulation of Csnk2b 1 0.26 0.07 2.46
19 INT122561 Negative_regulation of Gene_expression of Adipoq 12 0.56 14.02 2.26
20 INT135451 Positive_regulation of Positive_regulation of Adipoq 3 0.40 2.06 2.24
21 INT86184 Negative_regulation of Acsl1 10 0.34 20.45 2.23
22 INT138029 Binding of Adipoq 10 0.40 6.81 2.04
23 INT134633 Localization of Adipoq 9 0.60 6.39 2.03
24 INT255370 Gene_expression of Csnk2b 1 0.35 0.08 1.88
25 INT133480 Positive_regulation of Phosphorylation of Csnk2b 3 0.23 1.01 1.82
26 INT227273 Localization of Adipoq 22 0.72 18.04 1.72
27 INT188241 Negative_regulation of ADIPOQ 16 0.43 22.16 1.47
28 INT55619 Binding of Acsl1 8 0.31 9.91 1.22
29 INT227275 Negative_regulation of Gene_expression of Adipoq 19 0.53 19.51 1.15
30 INT213277 Positive_regulation of Gene_expression of ADIPOQ 14 0.50 17.7 1.14
31 INT20470 Positive_regulation of Acsl1 5 0.40 3.76 1.03
32 INT160140 Regulation of Binding of Adipoq 1 0.37 0.87 0.92
33 INT255360 Binding of Csnk2b 1 0.17 0.16 0.88
34 INT170742 Positive_regulation of Acsl1 6 0.44 6.98 0.86
35 INT227270 Regulation of Gene_expression of Adipoq 5 0.55 7.35 0.85
36 INT311464 Negative_regulation of Binding of Acsl1 1 0.03 2.71 0.83
37 INT151927 Regulation of Gene_expression of Adipoq 3 0.43 3.32 0.81
38 INT142013 Positive_regulation of Regulation of Adipoq 1 0.03 0.65 0.78
39 INT28020 Binding of Adipoq 10 0.36 11.49 0.77
40 INT190781 Binding of Acsl1 6 0.36 9.12 0.76
41 INT230901 Regulation of Acsl1 2 0.03 1.65 0.75
42 INT114608 Negative_regulation of Transcription of Acsl1 1 0.27 0.48 0.75
43 INT114609 Transcription of Acsl1 1 0.45 0.47 0.74
44 INT255359 Regulation of Negative_regulation of Csnk2b 1 0.12 0 0.69
45 INT148756 Regulation of Adipoq 10 0.60 7.83 0.67
46 INT337755 Protein_catabolism of Acsl1 1 0.21 0.72 0.65
47 INT118310 Negative_regulation of Positive_regulation of Adipoq 2 0.34 2.47 0.61
48 INT179488 Positive_regulation of Transcription of Adipoq 3 0.37 0.5 0.6
49 INT170739 Gene_expression of Acsl1 8 0.65 7.02 0.5
50 INT227272 Transcription of Adipoq 8 0.64 8.29 0.49
51 INT83430 Positive_regulation of Binding of ADIPOQ 2 0.21 0.85 0.49
52 INT83434 Negative_regulation of Binding of ADIPOQ 1 0.39 1.14 0.45
53 INT255362 Localization of Csnk2b 1 0.34 0.08 0.42
54 INT308980 Positive_regulation of Negative_regulation of Adipoq 3 0.33 2.3 0.4
55 INT170737 Localization of Acsl1 5 0.20 3.51 0.38
56 INT147014 Localization of Acsl1 3 0.60 2.35 0.36
57 INT311465 Positive_regulation of Localization of Acsl1 1 0.04 1.63 0.36
58 INT179491 Transcription of Adipoq 4 0.51 0.98 0.32
59 INT227268 Negative_regulation of Transcription of Adipoq 4 0.52 4.93 0.3
60 INT255358 Regulation of Gene_expression of Csnk2b 1 0.20 0 0.29
61 INT255364 Regulation of Csnk2b 1 0.12 0 0.22
62 INT253941 Positive_regulation of Localization of Adipoq 5 0.24 2.59 0.21
63 INT227795 Negative_regulation of Acsl1 3 0.21 3.05 0.21
64 INT311462 Positive_regulation of Gene_expression of Acsl1 1 0.04 2.13 0.2
65 INT150529 Positive_regulation of Negative_regulation of Adipoq 2 0.37 1.76 0.18
66 INT197872 Regulation of Regulation of Adipoq 3 0.35 1.11 0.17
67 INT235268 Positive_regulation of Gene_expression of Acsl1 2 0.49 1.96 0.17
68 INT28026 Positive_regulation of Binding of Adipoq 1 0.27 0 0.17
69 INT137455 Protein_catabolism of ADIPOQ 1 0.66 0.25 0.17
70 INT228162 Negative_regulation of Localization of Adipoq 1 0.38 1.29 0.17
71 INT116264 Negative_regulation of Gene_expression of Acsl1 1 0.20 0.2 0.17
72 INT308978 Negative_regulation of Regulation of Adipoq 1 0.28 0.92 0.17
73 INT263001 Regulation of Gene_expression of ADIPOQ 5 0.45 3.77 0.16
74 INT163262 Transcription of ADIPOQ 5 0.52 2.81 0.14
75 INT227794 Regulation of Acsl1 4 0.26 3.25 0.14
76 INT262999 Negative_regulation of Gene_expression of ADIPOQ 7 0.43 9.52 0.12
77 INT157267 Negative_regulation of Localization of Adipoq 1 0.24 0.94 0.09
78 INT327816 Regulation of Positive_regulation of ADIPOQ 1 0.04 1.2 0.09
79 INT133479 Negative_regulation of Phosphorylation of Csnk2b 1 0.14 0.61 0.09
80 INT353069 Positive_regulation of Positive_regulation of ADIPOQ 1 0.13 1.75 0.05
81 INT245905 Negative_regulation of Transcription of ADIPOQ 1 0.42 1.26 0.05
82 INT301555 Gene_expression of Slc27a1 3 0.26 0.45 0.04
83 INT228584 Phosphorylation of Adipoq 1 0.38 0.61 0.04
84 INT251940 Positive_regulation of Transcription of ADIPOQ 1 0.01 0 0.04
85 INT240621 Negative_regulation of Localization of ADIPOQ 1 0.39 0.64 0.03
86 INT301580 Positive_regulation of Gene_expression of Slc27a1 1 0.15 0.23 0
87 INT332021 Negative_regulation of Phosphorylation of Acsl1 1 0.41 0 0
88 INT257464 Negative_regulation of Transcription of Adipoq 1 0.41 0.45 0
89 INT263530 Negative_regulation of Positive_regulation of ADIPOQ 1 0.31 1.43 0
90 INT301584 Binding of Slc27a1 1 0.10 0.07 0
91 INT332022 Phosphorylation of Acsl1 1 0.79 0 0
92 INT227262 Regulation of Transcription of Adipoq 1 0.35 0.47 0
93 INT336750 Regulation of Gene_expression of Acsl1 1 0.05 0.4 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox