GO:0033235

From wiki-pain
Jump to: navigation, search
Name positive regulation of protein sumoylation
Categary Process
Go Slim No
Go Link GO:0033235
Unique Molecular Interactions 66
Total Molecular Interactions 93
Total Single Events 965
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of protein sumoylation. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of protein sumoylation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT338167 Binding of CDKN2A and MC1R 1 0.42 6.14 5.76
2 INT319581 Binding of PIAS1 and TNFSF14 1 0.02 1.58 2.13
3 INT116815 Binding of Pias1 and Ppbp 1 0.36 0.86 1.92
4 INT162163 CDKN2A Positive_regulation of PLD2 1 0.24 0 1.24
5 INT306258 HDAC4 Negative_regulation of Gene_expression of TNF 1 0.09 0.89 0.78
6 INT200325 Ahrr Regulation of Oprm1 1 0.00 0.09 0.49
7 INT158032 Binding of CDKN2A and KRT20 1 0.28 0.59 0.4
8 INT204071 HP Positive_regulation of Gene_expression of CDKN2A 1 0.00 3.48 0.34
9 INT130803 MC1R Regulation of Positive_regulation of Cdkn2a 1 0.17 0.82 0.34
10 INT147593 Binding of CDK4 and CDKN2A 1 0.42 0.23 0.26
11 INT147592 Positive_regulation of Binding of CDK4 and CDKN2A 1 0.44 0.23 0.26
12 INT200331 Binding of Ahrr and Gtf3a 1 0.00 0.18 0.17
13 INT191355 HDAC4 Positive_regulation of Gene_expression of Shc1 1 0.02 1.07 0.16
14 INT191354 Negative_regulation of HDAC4 Positive_regulation of Gene_expression of Shc1 1 0.02 1.07 0.16
15 INT136855 Arf5 Positive_regulation of Cdkn2a 1 0.07 1.8 0.15
16 INT314856 Binding of Cdc7 and Cdkn2a 1 0.28 1.34 0.14
17 INT347638 Negative_regulation of Binding of Atp9a and Hdac4 1 0.01 0.97 0.14
18 INT302146 CDKN2A Regulation of CDKN1B 1 0.11 0.51 0.14
19 INT302144 CDKN2A Regulation of CDKN1A 1 0.11 0.51 0.14
20 INT314852 Binding of Cdkn2a and Tgfbr3 1 0.28 1.15 0.14
21 INT347639 Binding of Atp9a and Hdac4 1 0.01 0.97 0.14
22 INT138195 Binding of HDAC4 and Creb1 1 0.03 0.17 0.13
23 INT302178 CDKN1C Regulation of CDKN2A 1 0.09 0.26 0.08
24 INT302158 CDKN1A Regulation of CDKN2A 1 0.04 0.26 0.08
25 INT136856 Cdkn2a Positive_regulation of Arf5 1 0.01 0.9 0.08
26 INT302139 LAMTOR1 Regulation of CDKN2A 1 0.08 0.26 0.08
27 INT302157 MRPL28 Regulation of CDKN2A 1 0.09 0.26 0.08
28 INT302148 IFI27 Regulation of CDKN2A 1 0.11 0.26 0.08
29 INT204073 Binding of Cdkn2a and Cdk4 1 0.02 0.78 0.05
30 INT204072 Binding of Cdkn2a and Cdk6 1 0.02 0.78 0.05
31 INT284916 IL1RN Negative_regulation of HDAC4 1 0.00 1.66 0.03
32 INT314677 TP53 Regulation of Positive_regulation of CDKN2A 1 0.27 0.97 0.03
33 INT243109 Pprc1 Negative_regulation of Pias1 1 0.00 0.51 0.03
34 INT219423 Binding of AHR and ARNT 4 0.24 0.46 0
35 INT225228 Binding of Cdk4 and Cdkn2a 1 0.21 1.24 0
36 INT329680 BMI1 Negative_regulation of Gene_expression of CDKN2A 1 0.15 1.14 0
37 INT329676 CBX7 Regulation of Localization of CDKN2A 1 0.51 2.4 0
38 INT215707 Cdkn2a Negative_regulation of Cdkn1b 1 0.01 0 0
39 INT219418 ARNT Positive_regulation of Localization of AHR 1 0.25 0 0
40 INT246914 Binding of CDKN2A and Ifng 1 0.01 0.71 0
41 INT200647 HDAC4 Positive_regulation of CASP9 1 0.10 0.93 0
42 INT311404 Binding of CDKN2A and Celf1 1 0.32 0.07 0
43 INT185281 Binding of CDK6 and CDKN2A 1 0.29 0.87 0
44 INT204234 Binding of CDKN2A and TP53 1 0.43 1.27 0
45 INT225229 Binding of Cdk6 and Cdkn2a 1 0.19 1.25 0
46 INT353437 Negative_regulation of Trp53 Positive_regulation of Gene_expression of Cdkn2a 1 0.24 0.59 0
47 INT75104 Binding of CA2 and PIAS1 1 0.15 0.06 0
48 INT184956 ID1 Negative_regulation of CDKN2A 1 0.42 0.21 0
49 INT204078 Binding of CDKN2A and Cdk4 1 0.15 0.72 0
50 INT215699 Cdkn2a Negative_regulation of Cdkn1c 1 0.01 0 0
51 INT337352 Binding of ARNT and HIF1A 1 0.14 0.61 0
52 INT332894 Binding of Ahrr and Hdac3 1 0.01 0.08 0
53 INT215696 Cdkn2a Negative_regulation of Kras 1 0.00 0 0
54 INT219505 ARNT Positive_regulation of Positive_regulation of Ppib 1 0.50 0 0
55 INT329677 CDKN2A Regulation of CBX7 1 0.31 2.23 0
56 INT277610 Binding of Runx2 and Hdac4 1 0.32 0.78 0
57 INT247427 CDKN2A Negative_regulation of Negative_regulation of RB1 1 0.07 1.16 0
58 INT204077 Binding of CDKN2A and Cdk6 1 0.15 0.72 0
59 INT200650 HDAC4 Regulation of Gene_expression of AKT1 1 0.16 0.66 0
60 INT314685 TBX2 Negative_regulation of CDKN2A 1 0.32 1.16 0
61 INT332898 Binding of Ahrr and Aadac 1 0.00 0.08 0
62 INT200644 HDAC4 Positive_regulation of CASP8 1 0.07 0.92 0
63 INT329679 CBX7 Regulation of CDKN2A 1 0.31 4.18 0
64 INT314680 Positive_regulation of TBX2 Negative_regulation of CDKN2A 1 0.34 1.16 0
65 INT277611 Binding of Mef2c and Hdac4 1 0.34 1.12 0
66 INT311403 CDKN2A Regulation of Celf1 1 0.41 0.14 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of protein sumoylation. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of protein sumoylation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT94774 Regulation of CDKN2A 43 0.60 44.41 13.99
2 INT78472 Gene_expression of CDKN2A 223 0.78 173.76 13.61
3 INT92138 Binding of CDKN2A 28 0.37 25.64 7.47
4 INT104909 Binding of Pias1 11 0.37 3.67 6.72
5 INT125467 Positive_regulation of Gene_expression of CDKN2A 35 0.63 39.07 5.56
6 INT13295 Positive_regulation of Cdkn2a 18 0.68 13.02 5.47
7 INT125066 Negative_regulation of HDAC4 56 0.49 41.55 5.42
8 INT89794 Positive_regulation of CDKN2A 58 0.67 50.18 5.38
9 INT97878 Positive_regulation of Pias1 6 0.50 2.73 4.65
10 INT96071 Localization of PIAS1 6 0.71 4.44 3.79
11 INT8481 Regulation of PIAS1 4 0.45 0.47 3.44
12 INT78471 Regulation of Gene_expression of CDKN2A 13 0.45 12.52 3.28
13 INT78248 Negative_regulation of Cdkn2a 17 0.59 15.15 2.8
14 INT92141 Negative_regulation of CDKN2A 53 0.57 44.23 2.48
15 INT338170 Regulation of Regulation of CDKN2A 1 0.44 0.96 2.46
16 INT96070 Negative_regulation of PIAS1 3 0.35 1.08 2.23
17 INT97876 Gene_expression of Pias1 4 0.59 1.62 2.18
18 INT94772 Gene_expression of Cdkn2a 14 0.75 8.25 2.04
19 INT96881 Gene_expression of ARNT 8 0.50 3.27 1.98
20 INT57431 Binding of PIAS1 4 0.30 4.35 1.94
21 INT277591 Gene_expression of Hdac4 22 0.77 7.77 1.79
22 INT70595 Regulation of Pias1 1 0.53 0.34 1.66
23 INT8480 Gene_expression of PIAS1 3 0.78 1.73 1.57
24 INT78470 Negative_regulation of Gene_expression of CDKN2A 14 0.59 14.44 1.38
25 INT55950 Negative_regulation of Pias1 4 0.37 1.31 1.36
26 INT200266 Gene_expression of Ahrr 4 0.01 0.73 1.29
27 INT277581 Positive_regulation of Hdac4 4 0.50 1.47 1.25
28 INT8482 Positive_regulation of PIAS1 2 0.40 0.73 1.12
29 INT8479 Positive_regulation of Gene_expression of PIAS1 1 0.43 0.15 1.12
30 INT42104 Regulation of Cdkn2a 4 0.44 5.67 1.06
31 INT234473 Gene_expression of HDAC4 8 0.18 6.28 0.99
32 INT338168 Positive_regulation of Binding of CDKN2A 1 0.49 0.52 0.94
33 INT165655 Localization of Pias1 1 0.80 0.34 0.85
34 INT144429 Positive_regulation of Cdkn2a 7 0.58 4.05 0.78
35 INT129115 Negative_regulation of Cdkn2a 16 0.50 17.03 0.76
36 INT96072 Regulation of Localization of PIAS1 1 0.14 0 0.66
37 INT251026 Negative_regulation of Phosphorylation of CDKN2A 5 0.42 5.02 0.62
38 INT177886 Positive_regulation of Gene_expression of Cdkn2a 3 0.67 3.42 0.62
39 INT135325 Negative_regulation of Localization of PIAS1 1 0.35 1.09 0.62
40 INT147598 Negative_regulation of Positive_regulation of CDKN2A 3 0.41 1.47 0.59
41 INT60893 Protein_catabolism of PIAS1 1 0.83 0.33 0.57
42 INT242011 Localization of Cdkn2a 4 0.73 2.49 0.54
43 INT144701 Gene_expression of Cdkn2a 15 0.75 8.42 0.53
44 INT144431 Positive_regulation of Transcription of Cdkn2a 1 0.41 1.11 0.51
45 INT144426 Transcription of Cdkn2a 1 0.42 1.11 0.51
46 INT333910 Positive_regulation of Gene_expression of HDAC4 2 0.07 1.5 0.49
47 INT179685 Positive_regulation of HDAC4 3 0.24 4.09 0.48
48 INT220088 Positive_regulation of Positive_regulation of CDKN2A 4 0.49 4.04 0.44
49 INT252657 Positive_regulation of Phosphorylation of CDKN2A 2 0.45 3.09 0.42
50 INT42105 Regulation of Positive_regulation of Cdkn2a 1 0.44 0.33 0.42
51 INT96870 Transcription of ARNT 1 0.44 0.81 0.4
52 INT200249 Binding of Ahrr 4 0.01 0.2 0.38
53 INT277579 Binding of Hdac4 1 0.37 3.84 0.38
54 INT277604 Negative_regulation of Hdac4 4 0.51 2.89 0.36
55 INT277598 Regulation of Gene_expression of Hdac4 1 0.45 0.91 0.36
56 INT196323 Localization of Cdkn2a 8 0.73 9.1 0.32
57 INT251025 Phosphorylation of CDKN2A 4 0.61 3.19 0.32
58 INT228477 Positive_regulation of Gene_expression of Cdkn2a 2 0.11 1.3 0.29
59 INT124568 Regulation of HDAC4 5 0.24 3.03 0.27
60 INT184624 Localization of CDKN2A 8 0.74 7.87 0.25
61 INT238494 Regulation of Transcription of CDKN2A 1 0.16 5.62 0.25
62 INT96872 Positive_regulation of ARNT 2 0.32 1.82 0.23
63 INT96878 Positive_regulation of Gene_expression of ARNT 1 0.32 0.44 0.23
64 INT96880 Positive_regulation of Transcription of ARNT 1 0.30 0.44 0.23
65 INT197292 Positive_regulation of Ahrr 2 0.39 0.57 0.21
66 INT277584 Negative_regulation of Gene_expression of Hdac4 1 0.43 0.85 0.21
67 INT221777 Negative_regulation of Ahrr 1 0.01 0.58 0.21
68 INT277594 Positive_regulation of Localization of Hdac4 1 0.50 1.71 0.21
69 INT277593 Localization of Hdac4 1 0.75 2.07 0.2
70 INT277600 Positive_regulation of Gene_expression of Hdac4 1 0.60 0.48 0.2
71 INT241687 Binding of Cdkn2a 5 0.31 5.26 0.18
72 INT96874 Regulation of Transcription of ARNT 1 0.29 0.38 0.18
73 INT191155 Binding of HDAC4 5 0.08 2.79 0.17
74 INT277601 Positive_regulation of Positive_regulation of Hdac4 1 0.50 0.18 0.16
75 INT147149 Transcription of CDKN2A 8 0.67 6.85 0.15
76 INT225216 Negative_regulation of Negative_regulation of Cdkn2a 1 0.42 3.16 0.15
77 INT277582 Regulation of Hdac4 1 0.45 0.36 0.14
78 INT234460 Negative_regulation of Gene_expression of HDAC4 2 0.04 1.55 0.11
79 INT234465 Regulation of Negative_regulation of HDAC4 1 0.04 0.74 0.11
80 INT112001 Binding of Cdkn2a 1 0.24 0.35 0.1
81 INT273604 Regulation of Negative_regulation of Cdkn2a 1 0.12 0.68 0.09
82 INT319133 Localization of Ahrr 2 0.02 0.48 0.06
83 INT277599 Phosphorylation of Hdac4 1 0.82 3.24 0.05
84 INT315215 Negative_regulation of Binding of Cdkn2a 1 0.35 0.11 0.05
85 INT259662 Positive_regulation of Regulation of HDAC4 1 0.03 0.77 0.03
86 INT332926 Localization of HDAC4 1 0.10 0.11 0.03
87 INT219493 Binding of ARNT 3 0.23 1.4 0
88 INT94773 Negative_regulation of Gene_expression of Cdkn2a 3 0.41 0.65 0
89 INT219456 Localization of ARNT 2 0.48 0.61 0
90 INT282090 Regulation of Cdkn2a 2 0.33 2.02 0
91 INT308355 Negative_regulation of Gene_expression of Cdkn2a 2 0.48 1.42 0
92 INT200682 Phosphorylation of HDAC4 2 0.44 1.24 0
93 INT147151 Positive_regulation of Negative_regulation of CDKN2A 2 0.47 1.74 0
94 INT308400 Negative_regulation of Regulation of CDKN2A 1 0.40 0.87 0
95 INT172979 Regulation of Negative_regulation of CDKN2A 1 0.44 0.57 0
96 INT281337 Regulation of ARNT 1 0.05 0.59 0
97 INT281254 Negative_regulation of Negative_regulation of CDKN2A 1 0.08 1.44 0
98 INT277580 Regulation of Localization of Hdac4 1 0.39 0 0
99 INT147147 Positive_regulation of Transcription of CDKN2A 1 0.49 0 0
100 INT200668 Regulation of Phosphorylation of HDAC4 1 0.24 0.71 0
101 INT300095 Regulation of Gene_expression of PIAS1 1 0.10 1.59 0
102 INT277577 Transcription of Hdac4 1 0.69 0 0
103 INT185285 Negative_regulation of Transcription of CDKN2A 1 0.43 1.12 0
104 INT184623 Positive_regulation of Localization of CDKN2A 1 0.04 0.86 0
105 INT247424 Transcription of Cdkn2a 1 0.47 0.82 0
106 INT239368 Negative_regulation of Binding of HDAC4 1 0.06 1.44 0
107 INT281335 Negative_regulation of ARNT 1 0.02 0.31 0
108 INT197281 Transcription of Ahrr 1 0.38 0 0
109 INT338233 Regulation of Gene_expression of HDAC4 1 0.03 0.18 0
110 INT355162 Regulation of Localization of CDKN2A 1 0.40 1.13 0
111 INT277603 Negative_regulation of Phosphorylation of Hdac4 1 0.43 0.39 0
112 INT247425 Regulation of Transcription of Cdkn2a 1 0.18 0.82 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox