GO:0033267

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Name axon part
Categary Component
Go Slim No
Go Link GO:0033267
Unique Molecular Interactions 674
Total Molecular Interactions 829
Total Single Events 6607
Pain Genes Associated 26

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for axon part. They are ordered first by their pain relevance and then by number of times they were reported for axon part. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT223866 Ltp Positive_regulation of Positive_regulation of Mapk1 2 0.46 0.75 2.61
2 INT238914 Positive_regulation of CNR1 Positive_regulation of Phosphorylation of MAPK1 1 0.19 3.22 2.35
3 INT281084 Prkaca Positive_regulation of Mapk1 2 0.25 0 2.06
4 INT168715 Mapk8 Negative_regulation of Oprk1 1 0.18 0.26 1.75
5 INT168716 Mapk8 Negative_regulation of Insrr 1 0.01 0.25 1.75
6 INT346217 Braf Positive_regulation of Phosphorylation of Map2k1 1 0.22 3.23 1.72
7 INT167427 Mapk8 Regulation of Regulation of Tnf 1 0.26 2.83 1.7
8 INT21570 Binding of Cck and Mapk8 1 0.06 0 1.6
9 INT144280 ACP1 Negative_regulation of Phosphorylation of MAPK1 1 0.37 0.78 1.56
10 INT166360 Negative_regulation of Crhr1 Negative_regulation of Positive_regulation of Pomc 1 0.02 0.36 1.5
11 INT169800 Negative_regulation of Adrbk1 Positive_regulation of Positive_regulation of Mapk1 1 0.39 1.04 1.45
12 INT261831 Mapk1 Negative_regulation of Hspg2 1 0.00 1.26 1.42
13 INT148450 Gene_expression of Inhbe Positive_regulation of Mapk1 1 0.07 1.35 1.41
14 INT161670 H2-M3 Positive_regulation of Positive_regulation of Mapk1 1 0.14 0.73 1.41
15 INT106062 Positive_regulation of Oprl1 Positive_regulation of Mapk1 1 0.13 0.16 1.35
16 INT356317 Crhr1 Regulation of Gene_expression of Cea 1 0.18 0.65 1.33
17 INT356326 Crhr1 Regulation of Gene_expression of Helt 1 0.01 0.65 1.32
18 INT342165 Binding of Aqp1 and Nav1 1 0.25 0.57 1.25
19 INT166388 Binding of Gnb2l1 and Mapk1 1 0.49 0.49 1.21
20 INT121191 KCNMA1 Positive_regulation of Phosphorylation of MAPK1 1 0.06 0.61 1.18
21 INT169557 Cacna1h Positive_regulation of Mapk1 1 0.07 0.91 1.17
22 INT238916 CNR1 Positive_regulation of Phosphorylation of MAPK1 1 0.19 1.61 1.17
23 INT161509 Tlr4 Positive_regulation of Mapk8 1 0.15 0.3 1.16
24 INT161510 Tlr4 Positive_regulation of Mapk1 1 0.14 0.3 1.16
25 INT209088 Binding of Ceacam3 and Crhr1 1 0.34 1.26 1.11
26 INT167429 Negative_regulation of Mapk8 Negative_regulation of RYBP 1 0.01 1.11 1.09
27 INT139703 Tnf Positive_regulation of Mapk8 1 0.32 0.73 1.08
28 INT223875 Negative_regulation of Mapk8 Negative_regulation of Positive_regulation of Ltp 1 0.31 0 1.07
29 INT101067 MAP3K15 Positive_regulation of MAPK1 1 0.21 0.47 1.03
30 INT140652 IGF1 Positive_regulation of Phosphorylation of MAPK1 1 0.26 0.63 0.98
31 INT133616 Map2k1 Regulation of Fadd 1 0.04 0.29 0.97
32 INT133614 Map2k1 Regulation of Daxx 1 0.02 0.29 0.97
33 INT133615 Regulation of Map2k1 Regulation of Fadd 1 0.04 0.29 0.97
34 INT253836 Cck Regulation of DST 1 0.03 0.42 0.95
35 INT100018 TNF Positive_regulation of MAPK1 3 0.24 1.56 0.94
36 INT144281 ACP1 Negative_regulation of Positive_regulation of MAPK1 1 0.27 0.58 0.94
37 INT144285 ACP1 Negative_regulation of MAPK1 1 0.37 0.58 0.93
38 INT223871 Ltp Positive_regulation of Gene_expression of Mapk1 1 0.33 0 0.93
39 INT72917 Binding of Crh and Crhr1 4 0.32 0.73 0.91
40 INT302828 Mapkapk5 Positive_regulation of Mapk1 1 0.07 1.38 0.91
41 INT135446 Map2k1 Positive_regulation of Mapk3 1 0.54 0.25 0.91
42 INT343918 IgG Positive_regulation of Phosphorylation of MAPK1 1 0.01 3.57 0.91
43 INT188196 LIF Regulation of MAPK1 1 0.21 2.26 0.87
44 INT188214 OSM Regulation of MAPK1 1 0.20 2.27 0.87
45 INT190183 MAPK1 Regulation of CDCP1 1 0.00 1.19 0.85
46 INT262572 Ngf Positive_regulation of Mapk1 2 0.04 0.52 0.81
47 INT222024 Mapk8 Regulation of Mapk14 2 0.17 0.83 0.79
48 INT161520 H2-M3 Regulation of Positive_regulation of Mapk1 1 0.09 0.47 0.79
49 INT132977 Tac1 Positive_regulation of Mapk1 1 0.06 0.17 0.79
50 INT117909 Mastl Positive_regulation of Mapk1 1 0.04 0 0.79
51 INT152234 Mapk8 Positive_regulation of Localization of Nfkb1 1 0.33 0.26 0.78
52 INT152235 Mapk8 Positive_regulation of Localization of Tlr4 1 0.38 0.26 0.78
53 INT163830 ERBB2 Positive_regulation of MAPK1 1 0.06 1.63 0.76
54 INT98179 Aap Positive_regulation of Mapk8 1 0.01 0.75 0.74
55 INT168420 Positive_regulation of Mapk8 Positive_regulation of Phosphorylation of Jun 1 0.30 0.88 0.74
56 INT128813 Mapk8 Regulation of Gene_expression of Nos2 1 0.23 0.46 0.74
57 INT128404 Mapk1 Positive_regulation of Phosphorylation of Gja1 1 0.65 0.73 0.73
58 INT290548 Positive_regulation of Crhr1 Positive_regulation of Etf1 1 0.01 0.38 0.72
59 INT134476 Cdk5 Regulation of Map2k1 1 0.69 0.88 0.71
60 INT223873 Mapk8 Regulation of Positive_regulation of Ltp 1 0.24 0 0.71
61 INT166386 Mapk1 Regulation of Gene_expression of Gnb2l1 1 0.46 0.25 0.7
62 INT320633 Positive_regulation of MAPK1 Regulation of BCL2 1 0.04 1.21 0.7
63 INT194685 MAPK1 Regulation of Gene_expression of IL10 1 0.06 1.18 0.7
64 INT320634 Positive_regulation of MAPK1 Regulation of PBX2 1 0.03 1.21 0.7
65 INT223868 Mapk1 Positive_regulation of Creb1 2 0.17 0.34 0.68
66 INT223876 Mapk1 Positive_regulation of Atf6b 1 0.10 0 0.68
67 INT223869 Mapk8 Negative_regulation of Positive_regulation of Ltp 1 0.20 0 0.68
68 INT122190 Binding of Crhr1 and Ucn 4 0.49 0.65 0.67
69 INT211916 Fig4 Positive_regulation of Mapk1 1 0.13 0.25 0.66
70 INT191332 AMPH Positive_regulation of Mapk1 1 0.76 0 0.66
71 INT110458 Binding of Atf2 and Mapk8 1 0.35 0 0.66
72 INT330046 Mapk8 Negative_regulation of Prkcg 1 0.13 0.4 0.66
73 INT124477 MAP2K1 Positive_regulation of Positive_regulation of MAPK1 1 0.12 1.35 0.65
74 INT148173 Positive_regulation of Grm5 Positive_regulation of Phosphorylation of Mapk1 1 0.01 0.45 0.65
75 INT356329 Crhr1 Regulation of Cea 1 0.09 0.31 0.64
76 INT356314 Binding of Crhr1 and ORF61 1 0.00 0 0.63
77 INT100030 TNF Positive_regulation of Mapk8 1 0.12 1.57 0.63
78 INT281092 Adcy1 Positive_regulation of Mapk1 1 0.21 0 0.63
79 INT281090 Prkacb Positive_regulation of Mapk1 1 0.06 0 0.62
80 INT128812 Mapk8 Negative_regulation of Gene_expression of Nos2 1 0.19 0.37 0.61
81 INT89012 DST Positive_regulation of Insr 1 0.01 0.86 0.59
82 INT178437 Mapk8 Positive_regulation of Jun 3 0.40 2.69 0.58
83 INT291262 Positive_regulation of INS Positive_regulation of Mapk1 1 0.03 1.78 0.58
84 INT291258 INS Positive_regulation of Mapk1 1 0.04 1.77 0.58
85 INT115146 MAPK1 Positive_regulation of EGR1 3 0.13 2.43 0.57
86 INT148172 Mapk1 Positive_regulation of Phosphorylation of Kcnd2 1 0.49 0.55 0.57
87 INT356321 Positive_regulation of Crhr1 Positive_regulation of Cea 1 0.19 0.37 0.56
88 INT201949 CXCL10 Positive_regulation of Phosphorylation of MAPK1 1 0.15 0.79 0.55
89 INT121994 EGF Positive_regulation of Positive_regulation of MAPK1 1 0.25 0 0.55
90 INT253835 Binding of DST and Fos 1 0.02 0 0.55
91 INT356322 Positive_regulation of Crhr1 Positive_regulation of ORF61 1 0.00 0 0.54
92 INT323146 PRKCA Positive_regulation of MAPK1 1 0.02 0 0.54
93 INT200913 Dio1 Positive_regulation of Mapk8 1 0.00 0 0.53
94 INT85125 IL3 Positive_regulation of MAPK1 1 0.30 0.81 0.53
95 INT85121 CSF2 Positive_regulation of MAPK1 1 0.07 0.8 0.53
96 INT85115 IL5 Positive_regulation of MAPK1 1 0.14 0.81 0.53
97 INT171909 MAPK8 Positive_regulation of Gene_expression of MAPK1 1 0.08 1.55 0.52
98 INT171910 MAPK1 Positive_regulation of MAPK9 1 0.10 1.55 0.52
99 INT130161 IgG-2a Positive_regulation of Gene_expression of Crhr1 1 0.01 0 0.52
100 INT201939 CXCL10 Positive_regulation of MAPK1 1 0.11 0.72 0.52
101 INT171906 MAPK1 Positive_regulation of Gene_expression of MAPK14 1 0.08 1.55 0.52
102 INT130158 Pomc Regulation of Gene_expression of Crhr1 1 0.20 0 0.52
103 INT130163 Pomc Positive_regulation of Gene_expression of Crhr1 1 0.15 0 0.52
104 INT130159 IgG-2a Regulation of Gene_expression of Crhr1 1 0.01 0 0.52
105 INT171914 MAPK8IP3 Positive_regulation of Gene_expression of MAPK1 1 0.06 1.55 0.52
106 INT122872 SEMA6A Positive_regulation of MAPK1 1 0.56 0 0.52
107 INT205030 Crh Positive_regulation of Crhr1 2 0.54 1.33 0.51
108 INT131368 MAPK1 Positive_regulation of Bcar3 1 0.00 0.37 0.51
109 INT131369 MAPK1 Positive_regulation of Il4 1 0.01 0.37 0.51
110 INT356286 Ngf Regulation of Positive_regulation of Mapk1 1 0.03 0.76 0.5
111 INT356279 Gdnf Regulation of Positive_regulation of Mapk1 1 0.03 0.76 0.5
112 INT194676 Negative_regulation of MAPK1 Negative_regulation of Gene_expression of IL10 1 0.05 0.34 0.5
113 INT118485 CST3 Regulation of CTSH 1 0.36 0 0.49
114 INT102553 HGF Positive_regulation of Phosphorylation of MAPK1 1 0.40 0.49 0.48
115 INT114297 Apc Negative_regulation of Gene_expression of Fcer2a 1 0.03 0.96 0.48
116 INT185917 Binding of AR and MAPK1 1 0.07 0.5 0.47
117 INT102555 HGF Positive_regulation of MAPK1 1 0.38 0.47 0.47
118 INT265646 Binding of Mapk1 and Mapk14 1 0.01 1.53 0.46
119 INT254225 Mapk14 Positive_regulation of Mapk8 1 0.02 0.87 0.46
120 INT254198 Mapk1 Positive_regulation of Mapk8 1 0.01 0.87 0.46
121 INT254216 Mapk14 Positive_regulation of Mapk1 1 0.02 0.87 0.46
122 INT254222 Mapk1 Positive_regulation of Mapk14 1 0.02 0.86 0.46
123 INT108332 EGF Positive_regulation of Phosphorylation of MAPK1 5 0.48 1.85 0.45
124 INT190870 BDNF Positive_regulation of Phosphorylation of Mapk1 1 0.12 0.54 0.44
125 INT343846 MAPK1 Positive_regulation of FOS 1 0.04 1.29 0.44
126 INT223863 Positive_regulation of Mapk1 Positive_regulation of Positive_regulation of Ltp 1 0.31 0 0.43
127 INT264473 Il1a Positive_regulation of Mapk1 1 0.00 0 0.43
128 INT188211 IL6 Regulation of MAPK1 1 0.16 1.13 0.43
129 INT264476 Il1a Positive_regulation of Gene_expression of Mapk8 1 0.04 0 0.43
130 INT265647 Binding of Ephb1 and Mapk1 1 0.00 1.48 0.43
131 INT264471 Il1a Positive_regulation of Gene_expression of Mapk1 1 0.01 0 0.43
132 INT264475 Il1a Positive_regulation of Mapk8 1 0.04 0 0.43
133 INT238913 MAPK3 Regulation of Positive_regulation of MAPK1 1 0.11 0.39 0.42
134 INT161521 Negative_regulation of H2-M3 Positive_regulation of Mapk1 1 0.14 0.41 0.42
135 INT309157 Aqp1 Positive_regulation of Bdnf 1 0.00 0.74 0.42
136 INT244421 Binding of DST and Ctss 1 0.02 0.42 0.41
137 INT194722 Negative_regulation of MAPK1 Negative_regulation of Gene_expression of CRP 1 0.09 1.49 0.41
138 INT274864 Negative_regulation of Mapk1 Negative_regulation of Gene_expression of TNF 1 0.05 1.15 0.41
139 INT161522 H2-M3 Positive_regulation of Mapk1 1 0.15 0.41 0.41
140 INT274867 Negative_regulation of Mapk1 Negative_regulation of TNF 1 0.03 1.15 0.41
141 INT261652 Binding of MAPK1 and PSEN1 1 0.22 1.25 0.41
142 INT67633 Binding of DST and Gabrd 1 0.03 0 0.41
143 INT319312 Socs4 Positive_regulation of Mapk8 1 0.05 0.68 0.41
144 INT124260 Plat Positive_regulation of Mapk1 1 0.14 0.81 0.41
145 INT194705 Negative_regulation of MAPK1 Negative_regulation of Positive_regulation of IK 1 0.00 1.46 0.41
146 INT113474 MAPK1 Negative_regulation of TNF 1 0.13 0.23 0.4
147 INT346222 Positive_regulation of Braf Positive_regulation of Map2k1 1 0.15 0.67 0.39
148 INT152237 Mapk1 Positive_regulation of Localization of Tlr4 1 0.33 0.13 0.39
149 INT152239 Mapk1 Positive_regulation of Localization of Nfkb1 1 0.29 0.13 0.39
150 INT194713 MAPK1 Regulation of Gene_expression of TNF 1 0.10 1.66 0.38
151 INT179938 Negative_regulation of Mapk8 Negative_regulation of TNF 1 0.02 1.09 0.37
152 INT187233 Positive_regulation of Mapk8 Positive_regulation of Jun 1 0.12 0.92 0.37
153 INT264480 Il1a Positive_regulation of Phosphorylation of Mapk8 1 0.04 0 0.37
154 INT207643 Prkca Positive_regulation of Mapk1 1 0.09 0.17 0.37
155 INT122189 Binding of Crhr1 and Ucn2 2 0.08 0.27 0.36
156 INT304501 Binding of Ephb1 and Mapk1 1 0.18 0.69 0.36
157 INT274941 Ephb2 Regulation of Phosphorylation of Mapk1 1 0.19 0 0.36
158 INT309120 Edc4 Negative_regulation of Positive_regulation of Mapk8 1 0.01 1.03 0.36
159 INT308653 Proc Regulation of Gene_expression of Mapk8 1 0.00 1.48 0.36
160 INT304505 Binding of Mapk1 and Uts2d 1 0.01 0.64 0.36
161 INT304532 Binding of Mdk and Mapk1 1 0.02 0.63 0.35
162 INT274865 Positive_regulation of Mapk1 Negative_regulation of Gene_expression of TNF 1 0.04 1.08 0.35
163 INT304495 Trib3 Positive_regulation of Mapk1 1 0.02 1.4 0.35
164 INT304529 Negative_regulation of Binding of Mdk and Mapk1 1 0.02 0.63 0.35
165 INT144966 MAPK1 Positive_regulation of Localization of EGR1 1 0.08 0.83 0.35
166 INT167156 FPR1 Positive_regulation of MAPK1 1 0.18 0.09 0.35
167 INT330106 Racgap1 Positive_regulation of Positive_regulation of Mapk8 1 0.01 1.32 0.35
168 INT188193 Negative_regulation of EGF Positive_regulation of MAPK1 1 0.28 0.54 0.34
169 INT330105 Rac1 Positive_regulation of Mapk8 1 0.15 1.47 0.34
170 INT25526 Dst Regulation of Gh 1 0.00 0.26 0.34
171 INT156831 EGF Positive_regulation of MAPK1 2 0.45 0.27 0.33
172 INT190652 Mdk Positive_regulation of Phosphorylation of Mapk1 2 0.50 0.85 0.33
173 INT274866 Mapk1 Positive_regulation of Gene_expression of TNF 1 0.06 0.35 0.33
174 INT167155 FPR1 Positive_regulation of Phosphorylation of MAPK1 1 0.18 0.17 0.33
175 INT59602 Crhr1 Positive_regulation of Localization of LH 1 0.25 0 0.33
176 INT337112 Negative_regulation of Nr1d2-rs2 Positive_regulation of Mapk1 1 0.00 0.14 0.33
177 INT124475 MAP2K1 Positive_regulation of Positive_regulation of CPOX 1 0.04 0.68 0.33
178 INT280814 Positive_regulation of Mapk1 Positive_regulation of Transcription of Fos 1 0.02 0.06 0.33
179 INT356323 Binding of ac and Crhr1 1 0.01 0 0.32
180 INT330103 Rac1 Positive_regulation of Positive_regulation of Mapk8 1 0.14 1.24 0.32
181 INT284689 Binding of Tspo and Map3k12 1 0.00 0.59 0.32
182 INT348016 Binding of Mapk8 and Mapk8ip3 1 0.04 2.09 0.32
183 INT346286 ELANE Positive_regulation of MAPK1 1 0.06 0.65 0.32
184 INT346281 Binding of ELANE and MAPK1 1 0.04 0.65 0.32
185 INT291240 Map3k8 Positive_regulation of Positive_regulation of Mapk1 1 0.16 0.72 0.32
186 INT242164 Wnt2 Positive_regulation of Localization of Apc 1 0.13 1.53 0.32
187 INT110461 Binding of Mapk8 and Gtf3a 1 0.03 0 0.32
188 INT291241 Map3k8 Positive_regulation of Gene_expression of Mapk1 1 0.17 0.72 0.32
189 INT286708 Negative_regulation of Mapk1 Negative_regulation of Casp3 1 0.12 0 0.31
190 INT194710 MAPK1 Regulation of Gene_expression of IK 1 0.00 0.24 0.31
191 INT282421 Mapk8 Negative_regulation of Ins1 1 0.06 2.48 0.31
192 INT253153 TNF Positive_regulation of Mapk8 1 0.18 0.61 0.31
193 INT167983 Mapk8 Negative_regulation of gr 1 0.02 0.5 0.31
194 INT100029 TNF Positive_regulation of Mapk1 1 0.01 0.78 0.31
195 INT337111 Positive_regulation of Nr1d2-rs2 Negative_regulation of Positive_regulation of Mapk1 1 0.00 0.15 0.31
196 INT253155 TNF Positive_regulation of Positive_regulation of Mapk8 1 0.19 0.62 0.31
197 INT170496 Egf Positive_regulation of Mapk1 3 0.21 0.5 0.3
198 INT112797 Positive_regulation of CASP1 Positive_regulation of MAPK1 1 0.02 0.16 0.3
199 INT356287 Ngf Positive_regulation of Mapk1 1 0.05 0.17 0.3
200 INT304504 Mapk1 Positive_regulation of Nos1 1 0.29 0.93 0.3

Single Events

The table below shows the top 100 pain related interactions that have been reported for axon part. They are ordered first by their pain relevance and then by number of times they were reported in axon part. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT95787 Positive_regulation of Mapk1 568 0.70 226.51 220.94
2 INT71789 Positive_regulation of MAPK1 396 0.70 234.44 89.27
3 INT92434 Phosphorylation of Mapk1 287 0.82 91.65 83.46
4 INT48934 Positive_regulation of Mapk1 157 0.70 60.61 61.72
5 INT71786 Phosphorylation of MAPK1 256 0.82 110.09 46.17
6 INT92437 Positive_regulation of Phosphorylation of Mapk1 113 0.70 32.19 40.29
7 INT114751 Gene_expression of Mapk1 137 0.76 60.14 39.98
8 INT102611 Negative_regulation of Positive_regulation of Mapk1 74 0.58 35.57 39.37
9 INT84260 Positive_regulation of Mapk8 124 0.69 72.84 35.98
10 INT109434 Phosphorylation of Mapk1 110 0.82 61.64 34.05
11 INT95734 Phosphorylation of Mapk8 108 0.82 49.92 33.52
12 INT48925 Gene_expression of Mapk1 95 0.74 42.21 32.91
13 INT96913 Positive_regulation of Mapk8 179 0.69 130.44 32.2
14 INT117112 Negative_regulation of Mapk1 87 0.56 40.34 31.18
15 INT104567 Gene_expression of Aqp1 47 0.78 44.84 28.68
16 INT83708 Negative_regulation of MAPK1 156 0.57 84.93 27.85
17 INT95788 Positive_regulation of Positive_regulation of Mapk1 83 0.69 24.75 25.84
18 INT12124 Gene_expression of MAPK1 141 0.75 82.4 25.58
19 INT99068 Gene_expression of Mapk8 62 0.78 33.57 21.25
20 INT91462 Positive_regulation of Phosphorylation of MAPK1 99 0.67 40.28 18.99
21 INT109316 Negative_regulation of Mapk8 72 0.59 50.59 17.24
22 INT104493 Negative_regulation of Mapk8 56 0.53 27.76 16.86
23 INT95790 Regulation of Mapk1 55 0.61 21.17 16.31
24 INT9751 Localization of Crhr1 26 0.78 10.47 15.69
25 INT111462 Negative_regulation of Phosphorylation of Mapk1 45 0.57 19.49 15.59
26 INT75531 Regulation of MAPK1 70 0.61 34.39 15.42
27 INT128401 Positive_regulation of Positive_regulation of Mapk1 39 0.70 10.88 15.38
28 INT80688 Positive_regulation of Positive_regulation of MAPK1 72 0.69 39.35 14.11
29 INT95738 Positive_regulation of Phosphorylation of Mapk8 40 0.70 23.46 13.88
30 INT150676 Positive_regulation of Gene_expression of Mapk1 30 0.45 10.06 12.37
31 INT119396 Regulation of Positive_regulation of Mapk1 22 0.61 7.88 12.25
32 INT109315 Gene_expression of Mapk8 70 0.78 45.46 11.65
33 INT96915 Phosphorylation of Mapk8 73 0.81 40.69 11.44
34 INT75525 Negative_regulation of Positive_regulation of MAPK1 40 0.59 25.15 11.15
35 INT104039 Positive_regulation of Crhr1 15 0.70 8.34 10.99
36 INT48921 Regulation of Mapk1 25 0.49 19.51 10.41
37 INT145695 Regulation of Mapk8 26 0.62 14.67 9.83
38 INT67101 Gene_expression of DST 47 0.54 25.92 9.59
39 INT94196 Negative_regulation of Phosphorylation of MAPK1 60 0.59 31.64 9.16
40 INT109432 Negative_regulation of Phosphorylation of Mapk1 19 0.54 7.01 8.98
41 INT111998 Positive_regulation of Positive_regulation of Mapk8 23 0.69 9.33 8.97
42 INT7572 Regulation of Crhr1 8 0.45 5.6 8.93
43 INT104481 Regulation of Mapk8 21 0.50 13.87 8.41
44 INT126848 Positive_regulation of Phosphorylation of Mapk1 30 0.50 15.94 8.34
45 INT96912 Positive_regulation of Phosphorylation of Mapk8 29 0.69 18.33 8.14
46 INT135443 Phosphorylation of Map2k1 11 0.80 2.44 8.01
47 INT171367 Phosphorylation of Map2k1 31 0.58 32.87 8
48 INT135441 Positive_regulation of Map2k1 15 0.67 6.6 7.87
49 INT7570 Transcription of Crhr1 7 0.66 6.6 7.6
50 INT99071 Positive_regulation of Gene_expression of Mapk8 16 0.55 9.87 7.58
51 INT74326 Gene_expression of Crhr1 25 0.66 9.7 7.48
52 INT80161 Positive_regulation of Crhr1 13 0.67 9.66 7.33
53 INT38644 Positive_regulation of DST 30 0.53 12.48 6.59
54 INT48928 Positive_regulation of Gene_expression of Mapk1 19 0.48 9.38 6.59
55 INT9753 Positive_regulation of Localization of Crhr1 8 0.49 1.72 6.55
56 INT93137 Negative_regulation of Map2k1 17 0.42 4.51 6.49
57 INT85655 Gene_expression of Crhr1 17 0.68 9.34 6.31
58 INT161352 Gene_expression of Map3k12 3 0.24 0.59 6.16
59 INT139964 Regulation of Phosphorylation of Mapk1 12 0.58 10.04 6.1
60 INT3819 Positive_regulation of Apc 36 0.69 27.03 6.02
61 INT677 Positive_regulation of CST3 20 0.67 17.47 6
62 INT130111 Regulation of Positive_regulation of MAPK1 14 0.36 11.01 5.9
63 INT71779 Positive_regulation of Gene_expression of MAPK1 27 0.47 21.41 5.39
64 INT128922 Negative_regulation of Gene_expression of Mapk8 6 0.34 3.93 5.36
65 INT156134 Regulation of Gene_expression of Aqp1 5 0.59 7.2 5.3
66 INT87022 Gene_expression of Apc 68 0.67 46.98 5.22
67 INT135440 Positive_regulation of Phosphorylation of Map2k1 5 0.49 1.32 5.22
68 INT14501 Gene_expression of CST3 28 0.75 25.77 5.16
69 INT135291 Positive_regulation of Positive_regulation of Mapk8 24 0.64 19.37 5.16
70 INT131717 Positive_regulation of Gene_expression of Mapk8 18 0.55 14.25 5.02
71 INT85328 Negative_regulation of Aqp1 5 0.54 6.02 4.94
72 INT18245 Negative_regulation of Localization of Crhr1 4 0.17 0.28 4.81
73 INT7568 Negative_regulation of Crhr1 8 0.43 4.63 4.77
74 INT158416 Localization of Mapk1 19 0.67 5.32 4.18
75 INT133244 Regulation of Positive_regulation of Mapk1 11 0.43 3.52 4.03
76 INT106065 Negative_regulation of MAP2K1 27 0.57 12.69 3.97
77 INT3817 Negative_regulation of Apc 29 0.58 22.12 3.91
78 INT113924 Binding of Mapk1 27 0.38 8.64 3.84
79 INT85326 Positive_regulation of Aqp1 7 0.65 5.9 3.71
80 INT11761 Negative_regulation of DST 13 0.42 7.66 3.65
81 INT85537 Regulation of Crhr1 4 0.45 1.64 3.53
82 INT104570 Localization of Aqp1 8 0.77 5.83 3.51
83 INT102076 Regulation of DST 15 0.22 10 3.5
84 INT21569 Binding of Mapk8 8 0.48 5.55 3.44
85 INT12388 Negative_regulation of Crhr1 17 0.59 9.47 3.33
86 INT163529 Negative_regulation of Positive_regulation of Mapk8 14 0.43 8.37 3.2
87 INT127336 Positive_regulation of Transcription of Crhr1 3 0.48 3.37 3.19
88 INT171368 Regulation of Phosphorylation of Mapk1 14 0.61 4.77 3.14
89 INT134470 Positive_regulation of Map2k1 74 0.49 46.07 3.02
90 INT110755 Negative_regulation of Positive_regulation of Mapk8 15 0.46 9.91 2.98
91 INT200895 Localization of Mapk1 6 0.67 2.08 2.82
92 INT9752 Regulation of Localization of Crhr1 3 0.44 0.36 2.82
93 INT169112 Negative_regulation of Positive_regulation of Mapk1 9 0.59 1.84 2.78
94 INT145821 Negative_regulation of Gene_expression of Mapk1 16 0.41 8.05 2.77
95 INT152927 Negative_regulation of Mapk1 16 0.41 5.85 2.73
96 INT95735 Regulation of Phosphorylation of Mapk8 7 0.50 1.88 2.69
97 INT95739 Negative_regulation of Phosphorylation of Mapk8 11 0.42 6.77 2.61
98 INT186116 Regulation of Gene_expression of MAPK1 9 0.44 5.85 2.32
99 INT640 Regulation of CST3 9 0.60 4.04 2.26
100 INT141721 Binding of Aqp1 5 0.37 1.77 2.15
101 INT203308 Regulation of Aqp1 4 0.48 2.59 2.13
102 INT170482 Regulation of Gene_expression of Mapk1 5 0.43 5.73 2.1
103 INT156270 Regulation of Positive_regulation of Mapk8 3 0.41 2.31 2.08
104 INT127756 Negative_regulation of Map2k1 10 0.41 6.69 2.04
105 INT109906 Localization of MAPK1 12 0.54 1.68 2.01
106 INT83709 Negative_regulation of Gene_expression of MAPK1 12 0.41 6.57 2.01
107 INT152696 Negative_regulation of Negative_regulation of Mapk8 1 0.32 0.35 2
108 INT109313 Binding of Mapk8 6 0.48 1.78 1.98
109 INT96916 Negative_regulation of Phosphorylation of Mapk8 16 0.52 9.68 1.97
110 INT85359 Negative_regulation of Map3k12 6 0.51 0.07 1.89
111 INT14500 Positive_regulation of Gene_expression of CST3 9 0.67 7.46 1.87
112 INT234090 Gene_expression of Dtnbp1 11 0.67 3.09 1.86
113 INT164864 Positive_regulation of Negative_regulation of Mapk8 1 0.31 1.33 1.82
114 INT135444 Regulation of Map2k1 4 0.44 1.15 1.77
115 INT299365 Transcription of Mapk8 9 0.72 5.91 1.75
116 INT257820 Positive_regulation of PAFAH1B1 1 0.68 11.09 1.69
117 INT3818 Regulation of Apc 13 0.39 12.52 1.68
118 INT281639 Binding of Map3k12 2 0.02 3.05 1.68
119 INT168714 Negative_regulation of Binding of Mapk8 1 0.36 0.18 1.62
120 INT169461 Regulation of Gene_expression of Mapk1 7 0.44 1.64 1.61
121 INT60975 Localization of CST3 6 0.78 2.4 1.58
122 INT135640 Negative_regulation of Dst 5 0.57 2.25 1.56
123 INT205025 Positive_regulation of Positive_regulation of Crhr1 2 0.70 1.22 1.51
124 INT130019 Regulation of Phosphorylation of MAPK1 6 0.49 3.6 1.5
125 INT29667 Positive_regulation of CRHR1 6 0.54 1.09 1.5
126 INT155801 Negative_regulation of Dtnbp1 4 0.59 3.97 1.5
127 INT93792 Binding of Crhr1 4 0.48 1.32 1.49
128 INT109507 Regulation of Map3k12 2 0.54 0 1.43
129 INT190646 Regulation of Regulation of Mapk1 1 0.30 1.16 1.43
130 INT104121 Positive_regulation of MAP2K1 8 0.61 4.84 1.41
131 INT153627 Binding of Mapk1 5 0.36 2.88 1.4
132 INT112934 Binding of Crhr1 7 0.46 2.69 1.39
133 INT220177 Binding of Apc 21 0.37 15.34 1.37
134 INT175525 Positive_regulation of Phosphorylation of Map2k1 8 0.33 7.02 1.37
135 INT71782 Gene_expression of MAP2K1 7 0.68 3.17 1.37
136 INT327824 Positive_regulation of Gene_expression of Aqp1 4 0.67 5.4 1.37
137 INT104027 Negative_regulation of Negative_regulation of MAPK1 6 0.56 2.87 1.35
138 INT73553 Gene_expression of Aqp1 23 0.67 4.65 1.34
139 INT110434 Positive_regulation of Gene_expression of Apc 20 0.50 11.37 1.3
140 INT38645 Negative_regulation of Positive_regulation of DST 3 0.29 1.05 1.29
141 INT354377 Negative_regulation of Negative_regulation of Map3k12 1 0.10 0 1.27
142 INT354379 Negative_regulation of Gene_expression of Map3k12 1 0.12 0 1.24
143 INT354378 Regulation of Gene_expression of Map3k12 1 0.12 0 1.23
144 INT679 Negative_regulation of CST3 7 0.57 4.63 1.22
145 INT154048 Negative_regulation of Gene_expression of Mapk8 5 0.43 4.43 1.22
146 INT140887 Binding of CRHR1 2 0.34 0.26 1.22
147 INT101027 Binding of DST 20 0.41 10.9 1.17
148 INT108740 Localization of Map3k12 2 0.68 0.09 1.15
149 INT36064 Binding of CST3 14 0.47 16.38 1.12
150 INT234087 Negative_regulation of Gene_expression of Dtnbp1 4 0.42 2.07 1.05
151 INT138287 Gene_expression of Map2k1 69 0.65 46.14 1.02
152 INT257824 Localization of PAFAH1B1 1 0.74 6.58 1
153 INT242134 Localization of Apc 8 0.74 4.83 0.88
154 INT234079 Positive_regulation of Dtnbp1 4 0.61 1.29 0.85
155 INT155803 Transcription of Dtnbp1 3 0.71 3.09 0.85
156 INT200900 Localization of Mapk8 9 0.40 5.76 0.84
157 INT71778 Positive_regulation of Gene_expression of MAP2K1 2 0.36 0.37 0.81
158 INT74324 Positive_regulation of Gene_expression of Crhr1 6 0.49 2.91 0.79
159 INT26289 Positive_regulation of Map3k12 2 0.11 0 0.79
160 INT323368 Binding of Dtnbp1 1 0.48 6.03 0.79
161 INT77256 Negative_regulation of Gene_expression of Crhr1 5 0.40 2.52 0.77
162 INT165104 Negative_regulation of Negative_regulation of Mapk8 5 0.43 4.21 0.77
163 INT165105 Localization of Mapk8 7 0.69 4.45 0.76
164 INT194780 Regulation of Negative_regulation of MAPK1 3 0.32 3.42 0.76
165 INT211909 Regulation of Positive_regulation of Map2k1 1 0.21 0.47 0.76
166 INT180752 Gene_expression of PAFAH1B1 3 0.66 9.89 0.75
167 INT164489 Regulation of Gene_expression of Mapk8 2 0.44 0.65 0.74
168 INT290527 Positive_regulation of Localization of Crhr1 1 0.37 1.4 0.74
169 INT290534 Localization of Crhr1 1 0.56 1.4 0.74
170 INT117245 Gene_expression of CRHR1 3 0.51 3.45 0.73
171 INT7567 Negative_regulation of Transcription of Crhr1 1 0.37 0.48 0.71
172 INT168981 Negative_regulation of Disc1 2 0.52 2.93 0.7
173 INT257817 Regulation of PAFAH1B1 1 0.60 4.93 0.7
174 INT109603 Positive_regulation of Localization of CST3 1 0.45 0.61 0.67
175 INT155802 Negative_regulation of Transcription of Dtnbp1 3 0.58 2.26 0.63
176 INT244420 Positive_regulation of Gene_expression of DST 4 0.41 2.05 0.59
177 INT75524 Positive_regulation of Regulation of MAPK1 1 0.43 1.12 0.59
178 INT7563 Regulation of Transcription of Crhr1 1 0.17 0.59 0.59
179 INT168982 Negative_regulation of Negative_regulation of Disc1 1 0.42 1.28 0.54
180 INT190645 Positive_regulation of Negative_regulation of Mapk1 1 0.44 0.39 0.54
181 INT104120 Positive_regulation of Positive_regulation of MAP2K1 1 0.49 0 0.54
182 INT170475 Negative_regulation of Gene_expression of Mapk1 7 0.41 2.44 0.53
183 INT356301 Negative_regulation of Positive_regulation of Crhr1 1 0.19 0.44 0.5
184 INT236915 Binding of Map2k1 2 0.15 1.51 0.49
185 INT257816 Negative_regulation of PAFAH1B1 1 0.58 3.66 0.49
186 INT109911 Positive_regulation of Localization of MAPK1 4 0.33 0.56 0.48
187 INT151720 Negative_regulation of Positive_regulation of Apc 3 0.37 2.15 0.46
188 INT301056 Transcription of Mapk8 1 0.06 1.22 0.45
189 INT159151 Negative_regulation of Negative_regulation of Mapk1 1 0.32 0.38 0.45
190 INT143392 Transcription of Crhr1 1 0.61 0.38 0.43
191 INT214136 Localization of DST 7 0.65 2.59 0.42
192 INT152151 Regulation of Gene_expression of Apc 4 0.44 3.87 0.42
193 INT323370 Regulation of Dtnbp1 1 0.45 0.83 0.42
194 INT202347 Gene_expression of Map2k4 13 0.74 11.68 0.4
195 INT138282 Positive_regulation of Gene_expression of Map2k1 13 0.49 7.46 0.39
196 INT274923 Protein_catabolism of Mapk1 1 0.47 0 0.39
197 INT274911 Positive_regulation of Protein_catabolism of Mapk1 1 0.27 0 0.39
198 INT187209 Negative_regulation of Localization of Mapk8 1 0.22 0.93 0.39
199 INT135638 Binding of Dst 4 0.36 2.76 0.38
200 INT304528 Gene_expression of Map2k1 3 0.58 1.76 0.37
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