GO:0033270

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Name paranode region of axon
Categary Component
Go Slim No
Go Link GO:0033270
Unique Molecular Interactions 82
Total Molecular Interactions 111
Total Single Events 1045
Pain Genes Associated 10

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for paranode region of axon. They are ordered first by their pain relevance and then by number of times they were reported for paranode region of axon. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT211694 Binding of Cntnap1 and Nav1 1 0.04 0 3.14
2 INT105716 Vta1 Regulation of Nfasc 1 0.14 0 1.89
3 INT334633 Binding of Cntnap1 and Nav1 1 0.10 1.36 1.48
4 INT344973 Negative_regulation of Mmp23 Regulation of Negative_regulation of Mag 1 0.01 1.14 0.99
5 INT63488 Sptan1 Positive_regulation of Rtcd1 1 0.03 0.34 0.91
6 INT52759 Oprd1 Regulation of Sptan1 1 0.03 0 0.9
7 INT52761 Dll1 Regulation of Sptan1 1 0.07 0 0.89
8 INT152835 Prkcg Regulation of Phosphorylation of Nfasc 1 0.10 0.21 0.87
9 INT344974 Lpar1 Regulation of Gene_expression of Mag 1 0.25 0.98 0.76
10 INT167795 Negative_regulation of LPA Negative_regulation of Mag 1 0.01 0.84 0.64
11 INT167794 LPA Negative_regulation of Mag 1 0.01 0.77 0.63
12 INT194914 Mtx1 Regulation of Gene_expression of Nfasc 1 0.00 0.71 0.58
13 INT331675 Binding of Drd1a and Sptan1 1 0.03 0.33 0.4
14 INT152240 Nfasc Regulation of Gene_expression of Nos2 1 0.06 0.19 0.36
15 INT237640 Nfasc Regulation of Gene_expression of Ank3 1 0.01 0.23 0.32
16 INT237634 Nfasc Positive_regulation of Gene_expression of Ank3 1 0.02 0.23 0.32
17 INT237635 Cntn1 Regulation of Nfasc 1 0.04 0.22 0.3
18 INT237638 Cntn1 Positive_regulation of Nfasc 1 0.07 0.22 0.3
19 INT237641 Binding of Cntnap1 and Nfasc 2 0.36 0.1 0.29
20 INT348755 Plat Regulation of Gene_expression of Cldn5 1 0.10 0.45 0.25
21 INT147590 Binding of Muc1 and Mag 1 0.26 3.29 0.23
22 INT241451 Mag Positive_regulation of Ngfr 1 0.09 0.1 0.21
23 INT237643 Binding of Cntn1 and Nfasc 1 0.06 0.05 0.21
24 INT237642 Binding of Ank3 and Nfasc 1 0.02 0 0.2
25 INT237639 Binding of Nfasc and Gnptab 1 0.01 0 0.2
26 INT265048 INCENP Positive_regulation of Positive_regulation of Nfasc 1 0.00 0.69 0.19
27 INT165335 Ltf Regulation of Mag 1 0.03 0.37 0.19
28 INT202508 Gpbar1 Positive_regulation of Positive_regulation of Nfasc 1 0.00 0.57 0.19
29 INT273792 Cxcr2 Positive_regulation of Nfasc 1 0.08 0.29 0.17
30 INT241457 Binding of Mag and Ngfr 1 0.09 0.15 0.15
31 INT241458 Binding of Mag and Rtn4r 1 0.03 0.15 0.14
32 INT191759 NFASC Negative_regulation of ELANE 1 0.00 0.98 0.11
33 INT246535 Binding of Cel and Mag 1 0.01 7.26 0.1
34 INT355008 Binding of Mag and Rtn4r 1 0.02 0.36 0.1
35 INT273791 Ntf3 Positive_regulation of Nfasc 1 0.01 0.18 0.09
36 INT312840 Egr2 Regulation of Gene_expression of Mag 1 0.31 0.16 0.09
37 INT312842 Pou3f1 Regulation of Gene_expression of Mag 1 0.24 0.16 0.09
38 INT202505 Binding of Cd40lg and Positive_regulation of Positive_regulation of Nfasc 1 0.09 0.45 0.08
39 INT254491 Positive_regulation of Binding of Cntnap1 and Nfasc 1 0.02 0.1 0.08
40 INT205237 Cldn2 Regulation of Gene_expression of Cldn5 1 0.03 0.29 0.07
41 INT10986 Nfasc Regulation of Hal 1 0.00 0.07 0.07
42 INT205228 Cldn5 Regulation of Gene_expression of Cldn1 1 0.03 0.29 0.07
43 INT205245 Cldn5 Regulation of Gene_expression of Cldn3 1 0.02 0.29 0.07
44 INT205236 Cldn5 Regulation of Tjp1 1 0.03 0.28 0.07
45 INT205239 Cldn3 Regulation of Gene_expression of Cldn5 1 0.02 0.29 0.07
46 INT205232 Cldn5 Regulation of Gene_expression of Cldn2 1 0.03 0.29 0.07
47 INT205233 Cldn5 Regulation of Gene_expression of Ocln 1 0.03 0.28 0.07
48 INT205246 Cldn5 Regulation of Gene_expression of Tjp1 1 0.03 0.28 0.07
49 INT202506 Psmb8 Positive_regulation of Nfasc 1 0.01 0.59 0.06
50 INT191756 NFASC Positive_regulation of Gene_expression of IGKV1D-39 1 0.00 0.11 0.06
51 INT191760 NFASC Positive_regulation of Localization of MPO 1 0.00 0.55 0.04
52 INT241449 Mag Positive_regulation of Protein_catabolism of Ngfr 1 0.09 0 0.03
53 INT348757 Plat Negative_regulation of Cldn5 1 0.16 0.3 0.03
54 INT278210 Binding of Ciita and Nfasc 1 0.04 0.07 0.03
55 INT246640 GAST Positive_regulation of NFASC 1 0.00 1.26 0.03
56 INT246534 Mag Regulation of Ccl2 1 0.02 1.28 0
57 INT251073 Cldn3 Negative_regulation of Localization of Cldn5 1 0.35 0.26 0
58 INT180164 Gast Positive_regulation of Nfasc 1 0.02 1.31 0
59 INT262516 Binding of Sema6a and Sptan1 1 0.01 0.47 0
60 INT323571 Lipg Positive_regulation of Positive_regulation of Mag 1 0.00 0.15 0
61 INT202507 Nfasc Positive_regulation of Gene_expression of Bcl2 1 0.10 0.7 0
62 INT251069 Binding of Cldn5 and Positive_regulation of Foxo1 1 0.09 0.15 0
63 INT246536 Mag Regulation of Gene_expression of Cel 1 0.01 1.28 0
64 INT251068 Gopc Regulation of Gene_expression of Cldn5 1 0.19 0 0
65 INT325420 Ghrl Regulation of Mag 1 0.02 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for paranode region of axon. They are ordered first by their pain relevance and then by number of times they were reported in paranode region of axon. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT167856 Gene_expression of Nfasc 74 0.71 39.29 23.64
2 INT8634 Gene_expression of Nfasc 23 0.68 9.16 14.96
3 INT47702 Gene_expression of Sptan1 24 0.76 7.6 11.36
4 INT180163 Positive_regulation of Nfasc 49 0.40 31.96 9.41
5 INT8632 Regulation of Nfasc 15 0.54 2.87 9.08
6 INT8633 Negative_regulation of Gene_expression of Nfasc 1 0.51 0.6 8.79
7 INT186623 Negative_regulation of Mag 13 0.42 12.22 6.48
8 INT194905 Positive_regulation of Gene_expression of Nfasc 16 0.10 11.87 6.19
9 INT8631 Negative_regulation of Nfasc 12 0.42 3.33 5.71
10 INT211690 Gene_expression of Cntnap1 1 0.06 1.03 5.5
11 INT237619 Gene_expression of Mag 34 0.63 31 5.07
12 INT78515 Negative_regulation of Mag 10 0.54 9.4 5.06
13 INT14726 Gene_expression of Mag 8 0.42 8.23 5
14 INT162624 Regulation of Mag 9 0.44 8.28 4.28
15 INT61366 Positive_regulation of NFASC 16 0.26 13.75 4.11
16 INT108579 Localization of Nfasc 18 0.72 3.47 4
17 INT86280 Positive_regulation of Nfasc 14 0.62 6.56 3.84
18 INT52755 Positive_regulation of Sptan1 6 0.67 1.57 3.82
19 INT194913 Localization of Nfasc 17 0.36 9.91 3.76
20 INT98740 Regulation of Mag 2 0.24 4.53 3.42
21 INT52756 Negative_regulation of Sptan1 7 0.42 1.31 3.19
22 INT78516 Positive_regulation of Mag 4 0.43 3.56 3.12
23 INT194898 Regulation of Gene_expression of Nfasc 1 0.03 4.51 2.93
24 INT125905 Gene_expression of Cldn5 7 0.57 4.33 2.66
25 INT94085 Binding of NFASC 10 0.17 7.1 2.5
26 INT54435 Binding of Sptan1 8 0.36 4.7 2.44
27 INT180161 Binding of Nfasc 23 0.48 10.92 2.4
28 INT211684 Regulation of Gene_expression of Cntnap1 1 0.04 0.54 2.38
29 INT194893 Positive_regulation of Positive_regulation of Nfasc 7 0.27 6.19 2.35
30 INT125902 Positive_regulation of Gene_expression of Cldn5 5 0.51 3.13 2.16
31 INT54433 Transcription of Sptan1 1 0.69 0 2.03
32 INT194895 Negative_regulation of Nfasc 22 0.37 9.94 1.98
33 INT90826 Localization of NFASC 8 0.17 6.01 1.97
34 INT138878 Negative_regulation of Gene_expression of Cldn5 4 0.37 2.81 1.96
35 INT194907 Transcription of Nfasc 1 0.05 3.25 1.94
36 INT241412 Positive_regulation of Mag 25 0.37 8.59 1.8
37 INT112270 Negative_regulation of Cntnap1 4 0.57 1.74 1.76
38 INT52758 Negative_regulation of Positive_regulation of Sptan1 2 0.57 0.33 1.73
39 INT317882 Regulation of Gene_expression of Mag 7 0.37 5.17 1.61
40 INT94083 Gene_expression of NFASC 8 0.19 4.19 1.52
41 INT107969 Negative_regulation of NFASC 6 0.24 2.58 1.44
42 INT4928 Binding of Mag 9 0.26 7.62 1.42
43 INT211685 Binding of Cntnap1 1 0.04 0.18 1.42
44 INT216023 Negative_regulation of Negative_regulation of Mag 2 0.31 2.52 1.29
45 INT104170 Phosphorylation of Nfasc 4 0.34 1.38 1.2
46 INT94080 Negative_regulation of Binding of NFASC 2 0.14 1.36 1.18
47 INT50389 Localization of Sptan1 3 0.73 0 1.16
48 INT194901 Regulation of Nfasc 8 0.21 5.76 1.15
49 INT80736 Protein_catabolism of Sptan1 5 0.32 3.32 1.1
50 INT194909 Positive_regulation of Transcription of Nfasc 1 0.04 1.82 1.05
51 INT71987 Regulation of Gene_expression of Sptan1 1 0.60 0 1.03
52 INT194891 Negative_regulation of Gene_expression of Nfasc 4 0.37 1.99 1.02
53 INT130793 Positive_regulation of Gene_expression of Nfasc 1 0.02 1.76 0.99
54 INT151906 Positive_regulation of Positive_regulation of Nfasc 2 0.11 1.98 0.98
55 INT159986 Positive_regulation of Gene_expression of Sptan1 2 0.68 1.1 0.95
56 INT55647 Binding of Nfasc 5 0.35 5.43 0.94
57 INT344966 Negative_regulation of Regulation of Mag 1 0.42 1.62 0.93
58 INT241413 Localization of Mag 2 0.27 0.57 0.92
59 INT109397 Binding of Mag 6 0.08 4.38 0.91
60 INT194904 Negative_regulation of Localization of Nfasc 1 0.03 1.62 0.91
61 INT251063 Gene_expression of Cldn5 12 0.59 3.73 0.79
62 INT167788 Negative_regulation of Negative_regulation of Mag 1 0.20 1.02 0.78
63 INT167789 Regulation of Positive_regulation of Mag 1 0.21 1.01 0.78
64 INT87758 Negative_regulation of Regulation of Nfasc 1 0.42 0 0.75
65 INT82117 Phosphorylation of NFASC 2 0.46 1.82 0.72
66 INT344969 Positive_regulation of Regulation of Mag 1 0.33 1.15 0.7
67 INT344970 Regulation of Regulation of Mag 1 0.32 1.15 0.7
68 INT344967 Positive_regulation of Negative_regulation of Mag 1 0.33 1.15 0.69
69 INT194911 Negative_regulation of Positive_regulation of Nfasc 5 0.23 3.33 0.67
70 INT211693 Regulation of Regulation of Cntnap1 1 0.04 0 0.67
71 INT344971 Regulation of Negative_regulation of Mag 1 0.19 1.08 0.66
72 INT211682 Regulation of Cntnap1 1 0.04 0 0.66
73 INT305872 Negative_regulation of Gene_expression of Cldn5 2 0.20 2.49 0.65
74 INT80737 Positive_regulation of Protein_catabolism of Sptan1 1 0.12 1.39 0.64
75 INT61365 Regulation of NFASC 3 0.21 1.85 0.58
76 INT141231 Negative_regulation of Cntnap1 2 0.32 1.18 0.58
77 INT142419 Regulation of Sptan1 2 0.38 2.52 0.55
78 INT104168 Protein_catabolism of Nfasc 4 0.89 1.31 0.52
79 INT211688 Positive_regulation of Gene_expression of Cntnap1 1 0.04 0.3 0.51
80 INT242444 Positive_regulation of Cldn5 2 0.24 0.99 0.5
81 INT194906 Negative_regulation of Transcription of Nfasc 1 0.03 0.95 0.48
82 INT237626 Binding of Cntnap1 2 0.35 0.25 0.47
83 INT317886 Positive_regulation of Gene_expression of Mag 5 0.09 4.41 0.41
84 INT134588 Positive_regulation of Positive_regulation of Sptan1 1 0.49 0 0.41
85 INT348754 Negative_regulation of Cldn5 1 0.17 0.75 0.4
86 INT115194 Negative_regulation of Positive_regulation of NFASC 1 0.14 0 0.38
87 INT237629 Localization of Cntnap1 2 0.73 0.2 0.34
88 INT194890 Positive_regulation of Localization of Nfasc 2 0.10 0.96 0.34
89 INT202067 Protein_catabolism of NFASC 1 0.04 0.79 0.34
90 INT8519 Localization of Mag 1 0.36 1.57 0.32
91 INT237621 Gene_expression of Cntnap1 2 0.75 1.06 0.31
92 INT211692 Localization of Cntnap1 2 0.20 0.07 0.29
93 INT291084 Localization of Cldn5 1 0.31 0.84 0.29
94 INT258314 Positive_regulation of Cntnap1 3 0.32 0.92 0.27
95 INT202488 Regulation of Positive_regulation of Nfasc 3 0.11 1.45 0.26
96 INT104167 Negative_regulation of Phosphorylation of Nfasc 1 0.24 0.76 0.23
97 INT202501 Regulation of Negative_regulation of Nfasc 2 0.21 1.42 0.22
98 INT202492 Phosphorylation of Nfasc 1 0.19 1.02 0.19
99 INT317342 Positive_regulation of Localization of Nfasc 1 0.62 0 0.17
100 INT158895 Regulation of Gene_expression of Cldn5 1 0.22 0.15 0.15
101 INT297226 Positive_regulation of Cntnap1 1 0.13 0.06 0.14
102 INT158901 Positive_regulation of Cldn5 1 0.19 0.14 0.14
103 INT241420 Phosphorylation of Mag 2 0.29 0.91 0.13
104 INT104171 Negative_regulation of Protein_catabolism of Nfasc 1 0.24 0.42 0.13
105 INT334673 Negative_regulation of Gene_expression of Mag 1 0.34 0.85 0.13
106 INT147588 Positive_regulation of Gene_expression of Mag 1 0.38 1.81 0.12
107 INT348751 Positive_regulation of Gene_expression of Cldn5 1 0.20 0.56 0.11
108 INT205214 Transcription of Cldn5 1 0.11 0.44 0.11
109 INT355012 Negative_regulation of Binding of Mag 1 0.09 0.38 0.11
110 INT104169 Positive_regulation of Protein_catabolism of Nfasc 1 0.19 0.35 0.11
111 INT305861 Regulation of Cldn5 1 0.13 0.55 0.11
112 INT127168 Positive_regulation of Positive_regulation of NFASC 1 0.02 0.71 0.1
113 INT202472 Protein_catabolism of Nfasc 1 0.18 0.85 0.09
114 INT254469 Positive_regulation of Binding of Nfasc 1 0.04 0.1 0.08
115 INT305862 Regulation of Gene_expression of Cldn5 1 0.08 0.22 0.07
116 INT247807 Localization of Cldn5 5 0.57 1.18 0.05
117 INT347866 Regulation of Gene_expression of Nfasc 1 0.15 0.07 0.03
118 INT323520 Protein_catabolism of Mag 1 0.12 0 0.03
119 INT323517 Positive_regulation of Positive_regulation of Mag 1 0.08 0.21 0
120 INT323521 Positive_regulation of Binding of Mag 1 0.07 0.24 0
121 INT335901 Regulation of Cntnap1 1 0.17 0.31 0
122 INT251051 Binding of Cldn5 1 0.28 0.25 0
123 INT348752 Negative_regulation of Negative_regulation of Cldn5 1 0.17 0.24 0
124 INT251049 Regulation of Binding of Cldn5 1 0.34 0.1 0
125 INT323509 Negative_regulation of Positive_regulation of Mag 1 0.08 0.26 0
126 INT216378 Positive_regulation of Gene_expression of NFASC 1 0.12 0.06 0
127 INT305871 Regulation of Localization of Cldn5 1 0.13 0 0
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