GO:0033280

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Name response to vitamin D
Categary Process
Go Slim No
Go Link GO:0033280
Unique Molecular Interactions 868
Total Molecular Interactions 1230
Total Single Events 9954
Pain Genes Associated 27

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for response to vitamin D. They are ordered first by their pain relevance and then by number of times they were reported for response to vitamin D. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT176477 Binding of CXCR3 and CXCL10 14 0.25 10.61 5.87
2 INT95068 Tlr4 Positive_regulation of IL1B 1 0.03 4.54 5.6
3 INT128296 Negative_regulation of IL1B Positive_regulation of Insr 1 0.10 1.36 4.52
4 INT128295 IL1B Positive_regulation of Insr 1 0.11 1.36 4.5
5 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 0.59 9.37 4.48
6 INT57985 Il1b Positive_regulation of Il6 5 0.59 1.66 3.53
7 INT128293 Negative_regulation of Aldh1a1 Positive_regulation of Insr 1 0.00 0.99 3.34
8 INT128292 Nts Positive_regulation of Insr 1 0.03 0.99 3.34
9 INT128291 Vom1r68 Positive_regulation of Insr 1 0.00 0.99 3.33
10 INT128294 Aldh1a1 Positive_regulation of Insr 1 0.00 0.99 3.33
11 INT64719 IL1B Positive_regulation of IL6 7 0.41 6.84 3.14
12 INT202965 Binding of STC2 and BAG3 1 0.02 7.86 2.96
13 INT150886 Il1a Regulation of Il1b 1 0.02 3.46 2.93
14 INT130721 Binding of IL1B and IL1RN 6 0.05 5.29 2.85
15 INT147107 TGFB1 Positive_regulation of Gene_expression of NGF 1 0.49 0.67 2.69
16 INT318998 IFNA1 Positive_regulation of Localization of CXCL10 1 0.15 2.09 2.39
17 INT94492 Il6 Positive_regulation of Gene_expression of Il1b 1 0.27 3.81 2.19
18 INT94491 Il1b Positive_regulation of Gene_expression of Tnf 1 0.25 3.81 2.19
19 INT94494 Il1b Positive_regulation of Gene_expression of Il6 1 0.27 3.81 2.19
20 INT209924 IL1B Negative_regulation of PPARA 1 0.20 4.38 2.17
21 INT202963 Binding of STC2 and CPP 1 0.02 5.16 2.04
22 INT51051 IL1B Positive_regulation of Localization of IL6 7 0.57 3.79 1.87
23 INT201940 Binding of IL8 and CXCL10 2 0.28 2.46 1.86
24 INT81920 Binding of IL1B and NFKB1 1 0.04 1.54 1.85
25 INT50993 Il1b Positive_regulation of Fos 2 0.40 0.43 1.84
26 INT302646 ARSA Positive_regulation of TGFB1 1 0.10 0.52 1.76
27 INT37840 Binding of Cyp27b1 and Oprd1 1 0.01 0 1.73
28 INT129717 TGFB1 Positive_regulation of Gene_expression of TNFRSF10D 3 0.38 4.29 1.71
29 INT100274 IL1RN Negative_regulation of IL1B 5 0.53 1.79 1.65
30 INT83093 IL1B Positive_regulation of BDKRB1 1 0.51 0.44 1.65
31 INT147108 TGFB1 Positive_regulation of Gene_expression of FN1 4 0.47 1.01 1.63
32 INT61134 IL10 Negative_regulation of Gene_expression of IL1B 3 0.46 2.13 1.63
33 INT89011 Lep Positive_regulation of Insr 1 0.19 2.41 1.57
34 INT74937 IL1B Positive_regulation of CPOX 5 0.18 1.13 1.55
35 INT91456 IL1B Positive_regulation of Gene_expression of CPOX 6 0.17 3.36 1.53
36 INT10276 Il1b Regulation of Gene_expression of Penk 1 0.61 0.85 1.5
37 INT150887 Il1b Regulation of Il10 1 0.04 1.74 1.47
38 INT158776 Il1b Regulation of Ephb1 1 0.15 0.09 1.46
39 INT190773 Il4 Negative_regulation of Gene_expression of Ptgs2 1 0.06 1.26 1.45
40 INT190774 Il4 Negative_regulation of Positive_regulation of Ptgs2 1 0.06 1.26 1.45
41 INT202958 Binding of STC2 and MCRS1 1 0.01 3.48 1.44
42 INT197111 Binding of IL1B and MCF2 1 0.02 2.12 1.4
43 INT95093 ITIH4 Positive_regulation of IL1B 1 0.43 1.04 1.32
44 INT95094 Negative_regulation of ITIH4 Positive_regulation of IL1B 1 0.36 1.04 1.32
45 INT121705 IL1B Positive_regulation of Gene_expression of MMP3 3 0.49 1.2 1.3
46 INT201942 DPP4 Negative_regulation of CXCL10 1 0.33 0.9 1.3
47 INT108386 IL1B Positive_regulation of MMP1 3 0.27 1.56 1.28
48 INT121703 IL1B Positive_regulation of Gene_expression of MMP1 3 0.49 1.14 1.27
49 INT108389 IL1B Positive_regulation of ADAMTS4 1 0.51 1.19 1.24
50 INT70039 IL1B Regulation of Negative_regulation of IL10 1 0.07 1.42 1.21
51 INT70038 IL1B Regulation of PRF1 1 0.05 1.42 1.21
52 INT70031 IL1B Regulation of Negative_regulation of PRF1 1 0.05 1.42 1.21
53 INT70030 IL1B Regulation of IL10 1 0.07 1.42 1.21
54 INT194861 Binding of IL1B and IL1R1 2 0.01 1.55 1.2
55 INT209926 IL1B Regulation of PPARA 1 0.21 2.45 1.2
56 INT75483 Binding of SGCG and TGFB1 1 0.52 2.27 1.19
57 INT142077 TGFB1 Negative_regulation of Binding of IDO1 1 0.15 2.07 1.19
58 INT289465 IRF6 Positive_regulation of IL1B 3 0.05 0.9 1.16
59 INT105240 POMC Positive_regulation of Gene_expression of CXCL10 1 0.07 1.18 1.16
60 INT94502 Il1b Positive_regulation of Gene_expression of Avp 1 0.28 1.97 1.15
61 INT94509 Il1b Positive_regulation of Gene_expression of AVP 1 0.36 1.96 1.15
62 INT66767 Il1b Positive_regulation of Pla2g10 1 0.05 0.47 1.13
63 INT94498 Il1b Positive_regulation of Gene_expression of Crh 1 0.24 1.94 1.13
64 INT66907 Il1b Positive_regulation of Localization of Oxt 2 0.78 0.18 1.12
65 INT260810 Binding of CXCL10 and CCL2 1 0.10 1.37 1.12
66 INT57982 Il1b Positive_regulation of Crh 2 0.38 0.98 1.09
67 INT107562 Penk Positive_regulation of Localization of Il1b 1 0.20 0.09 1.09
68 INT107561 Mtr Positive_regulation of Localization of Il1b 1 0.04 0.09 1.09
69 INT74939 IL1B Positive_regulation of Gene_expression of HGF 1 0.58 0.72 1.09
70 INT94500 Tnf Positive_regulation of Gene_expression of Il1b 1 0.25 1.9 1.09
71 INT107567 Hps4 Positive_regulation of Localization of Il1b 1 0.01 0.09 1.08
72 INT107564 Hps4 Regulation of Localization of Il1b 1 0.01 0.1 1.07
73 INT263048 Tgfb1 Positive_regulation of Gene_expression of Mmp2 1 0.13 0.81 1.07
74 INT107560 Penk Regulation of Localization of Il1b 1 0.18 0.1 1.07
75 INT57986 Il1b Regulation of Positive_regulation of Il6 2 0.39 0.23 1.05
76 INT126401 ITIH4 Positive_regulation of Gene_expression of Ptgs2 1 0.00 1.05 1.04
77 INT65986 IL1B Positive_regulation of PTGS2 3 0.32 2.05 1.03
78 INT128297 Il1b Positive_regulation of CRH 1 0.02 0.27 1.03
79 INT271875 IL1RN Negative_regulation of Binding of IL1B 1 0.01 1.3 1.01
80 INT102690 IL1B Positive_regulation of ITGAL 1 0.05 0.87 0.99
81 INT103651 IL1B Positive_regulation of Gene_expression of IL8 6 0.78 1.23 0.98
82 INT103796 IL1B Positive_regulation of Gene_expression of SELE 2 0.08 1 0.98
83 INT154255 Tnf Positive_regulation of IL1B 1 0.54 0.94 0.97
84 INT159111 Il1a Regulation of Gene_expression of Il1b 1 0.49 0.38 0.97
85 INT240123 MIR885 Negative_regulation of IL1B 1 0.01 1.57 0.96
86 INT129206 RYBP Positive_regulation of Gene_expression of TGFB1 1 0.00 1.04 0.95
87 INT130722 Binding of IL1B and Nfkb1 1 0.28 1.23 0.95
88 INT130725 Binding of IL1B and Il1rn 1 0.01 1.16 0.93
89 INT81919 Binding of HSF1 and IL1B 1 0.42 0.77 0.93
90 INT128859 Positive_regulation of RXRA Regulation of Gene_expression of OPRM1 1 0.05 0.26 0.9
91 INT63943 Il1b Positive_regulation of Localization of Calca 2 0.46 0.98 0.88
92 INT136349 Il1b Positive_regulation of Positive_regulation of Oprl1 1 0.22 0.27 0.88
93 INT149562 Tgfb1 Positive_regulation of CXCL10 1 0.00 0 0.88
94 INT149564 Tgfb1 Positive_regulation of Gene_expression of CXCL10 1 0.00 0 0.88
95 INT209928 IL1B Positive_regulation of MAPK14 2 0.15 1.69 0.87
96 INT224585 IL1B Positive_regulation of IL1RN 1 0.02 1.3 0.87
97 INT37839 Positive_regulation of Binding of Cyp27b1 and Oprd1 1 0.01 0 0.86
98 INT116559 Olr1627 Negative_regulation of Regulation of Ptgs2 1 0.01 1.52 0.86
99 INT270218 P2rx3 Positive_regulation of Pla2g4a 1 0.34 0.63 0.85
100 INT222985 CP Positive_regulation of Positive_regulation of TGFB1 1 0.00 1.57 0.85
101 INT196632 IL1B Positive_regulation of F2RL1 2 0.05 1.52 0.84
102 INT10275 Il1b Positive_regulation of Gene_expression of Penk 1 0.49 0.75 0.83
103 INT65011 IL1B Positive_regulation of PTGER2 4 0.08 0.92 0.82
104 INT94331 IFNG Positive_regulation of CXCL10 4 0.11 1.31 0.82
105 INT83094 IL1B Positive_regulation of Positive_regulation of BDKRB1 1 0.45 0.2 0.81
106 INT62176 Binding of PTGS2 and Ptgs1 2 0.00 0.69 0.79
107 INT200094 Negative_regulation of Jun Negative_regulation of Gene_expression of Ptgs2 1 0.01 2.87 0.78
108 INT161485 Il1b Regulation of Gene_expression of TGFB1 1 0.47 1.21 0.77
109 INT161483 Slc7a12 Regulation of Gene_expression of TGFB1 1 0.14 1.21 0.77
110 INT136795 Spp1 Positive_regulation of Chuk 1 0.11 1.54 0.77
111 INT173112 IL1B Positive_regulation of Gene_expression of VCAM1 2 0.43 1.34 0.76
112 INT76499 Binding of Insr and Adora2a 1 0.08 0 0.76
113 INT158068 Positive_regulation of Pparg Positive_regulation of Positive_regulation of PTGS2 1 0.01 0.28 0.76
114 INT161482 Il1b Negative_regulation of TGFB1 1 0.45 1.17 0.76
115 INT135180 IL1B Positive_regulation of Gene_expression of TNFSF11 2 0.76 1.73 0.75
116 INT278958 LEP Positive_regulation of IL1B 1 0.33 1.91 0.74
117 INT201941 IFNA1 Positive_regulation of Gene_expression of CXCL10 1 0.14 1.09 0.74
118 INT161484 Binding of TGFB1 and Il1b 1 0.37 1.16 0.73
119 INT150993 Sfpq Positive_regulation of Gene_expression of Il1b 1 0.04 0.7 0.72
120 INT74941 IL1B Positive_regulation of Gene_expression of PTGER2 1 0.08 0.48 0.72
121 INT65985 IL1B Positive_regulation of Gene_expression of PTGS2 3 0.23 2.62 0.71
122 INT73822 TAC1 Positive_regulation of Localization of IL1B 1 0.04 0.56 0.71
123 INT186674 Binding of BGLAP and CYP27A1 1 0.01 1.91 0.71
124 INT275554 Binding of CXCL10 and Cxcr3 1 0.03 2.18 0.71
125 INT73824 TFF2 Positive_regulation of Localization of IL1B 1 0.02 0.56 0.71
126 INT83838 Binding of CEACAM6 and Il1b 1 0.05 0 0.71
127 INT113500 IL1B Positive_regulation of Gene_expression of BHLHE23 1 0.18 0.1 0.71
128 INT95148 CEL Regulation of IL1B 1 0.24 0.88 0.7
129 INT334395 IL1B Positive_regulation of Tnf 1 0.11 2.83 0.69
130 INT250932 IL1B Regulation of Gene_expression of BDNF 1 0.06 0.24 0.69
131 INT346233 PREP Regulation of IL1B 1 0.05 1.44 0.69
132 INT172142 IL10 Positive_regulation of Protein_catabolism of IL1B 2 0.03 1.69 0.68
133 INT172132 IL4 Positive_regulation of Protein_catabolism of IL1B 2 0.02 1.69 0.68
134 INT66537 IL1B Positive_regulation of Gene_expression of Fos 1 0.02 0 0.68
135 INT302642 Binding of ARSA and TGFB1 1 0.05 0.28 0.68
136 INT185802 Binding of MMP7 and SPP1 1 0.33 1.71 0.68
137 INT354913 VDR Positive_regulation of TGFB1 1 0.05 1.33 0.67
138 INT70998 IL1B Regulation of Gene_expression of Icam1 1 0.44 0.95 0.67
139 INT150994 Sfpq Negative_regulation of Gene_expression of Il1b 1 0.03 0.69 0.66
140 INT88194 ZAK Positive_regulation of Gene_expression of IL1B 1 0.07 0.94 0.66
141 INT152111 IL1B Negative_regulation of Ltp 1 0.03 0.85 0.66
142 INT270763 IL1B Negative_regulation of IKBKB 1 0.04 1.13 0.66
143 INT116441 IL1B Positive_regulation of Gene_expression of CCL2 2 0.04 0.62 0.65
144 INT114947 YY1 Positive_regulation of Gene_expression of RXRA 1 0.33 0.25 0.65
145 INT222253 Binding of Cxcl10 and Fig4 1 0.09 0.66 0.65
146 INT184193 HRAS Negative_regulation of Gene_expression of IL1B 1 0.00 1.12 0.65
147 INT97508 Negative_regulation of Il1b Positive_regulation of Crh 1 0.31 0.89 0.65
148 INT114951 PPARA Positive_regulation of Gene_expression of RXRA 1 0.34 0.25 0.64
149 INT172139 IL4 Negative_regulation of IL1B 1 0.02 0.85 0.63
150 INT60328 Il1b Positive_regulation of Tnf 2 0.29 1.84 0.62
151 INT71526 Regulation of Il1b Positive_regulation of Il6 1 0.17 0.14 0.62
152 INT176475 IL1B Positive_regulation of Gene_expression of ICAM1 1 0.02 0.56 0.62
153 INT71942 Negative_regulation of PTGS2 Negative_regulation of VN1R106P 1 0.00 0.07 0.62
154 INT61826 Tnf Negative_regulation of Il1b 1 0.39 0.89 0.62
155 INT101320 Negative_regulation of Ptgs1 Positive_regulation of Ptgs2 1 0.03 0.2 0.62
156 INT46493 Binding of Insr and Oxt 1 0.14 0 0.62
157 INT220155 IL1RN Regulation of IL1B 2 0.50 0.93 0.61
158 INT137017 Tgfb1 Positive_regulation of Gene_expression of Acta2 1 0.00 0.84 0.61
159 INT103214 Binding of Il1b and Pnoc 1 0.40 0.23 0.61
160 INT114949 NCOA1 Positive_regulation of Gene_expression of RXRA 1 0.13 0.24 0.61
161 INT71944 PTGS2 Negative_regulation of VN1R106P 1 0.00 0.07 0.61
162 INT285467 Negative_regulation of Binding of IL1B and IL1RN 1 0.05 1.33 0.61
163 INT128814 Ephb1 Negative_regulation of Gene_expression of Il1b 1 0.02 0.37 0.61
164 INT281132 Binding of Ccr3 and Cxcl10 1 0.00 0.25 0.6
165 INT276217 Pdk1 Positive_regulation of Positive_regulation of Insr 1 0.05 0.1 0.6
166 INT66768 Il1b Positive_regulation of Transcription of Pla2g10 1 0.05 0.22 0.6
167 INT105848 Il1b Positive_regulation of Gene_expression of Cpox 1 0.12 0.41 0.59
168 INT81915 HSF1 Negative_regulation of IL1B 1 0.51 0.65 0.59
169 INT89010 Arc Positive_regulation of Insr 1 0.08 0.86 0.59
170 INT81917 HSF1 Positive_regulation of IL1B 1 0.41 0.65 0.59
171 INT128810 Il1b Positive_regulation of Gene_expression of Nos2 1 0.04 0.31 0.59
172 INT96240 Il13 Negative_regulation of Il1b 1 0.17 0.6 0.59
173 INT89012 DST Positive_regulation of Insr 1 0.01 0.86 0.59
174 INT96242 Il13 Negative_regulation of Gene_expression of Il1b 1 0.15 0.67 0.59
175 INT137247 Slc6a14 Negative_regulation of Ptgs2 2 0.19 1.38 0.58
176 INT137248 Slc6a14 Negative_regulation of Gene_expression of Ptgs2 1 0.19 1.32 0.58
177 INT125546 Arsa Negative_regulation of Gene_expression of PTGS2 1 0.00 0.53 0.58
178 INT87294 SERPINA3 Negative_regulation of PTGS2 1 0.25 0.6 0.58
179 INT202970 Binding of STC2 and CAP1 1 0.00 1.25 0.58
180 INT128603 Il1b Positive_regulation of Gene_expression of Fos 1 0.50 0.59 0.58
181 INT172144 IL4 Negative_regulation of Transcription of PLA2G4A 1 0.02 0.82 0.58
182 INT58342 Calca Negative_regulation of Localization of IL1B 1 0.00 0.6 0.58
183 INT54620 IL1B Positive_regulation of Crh 1 0.01 0.39 0.58
184 INT176471 TNF Positive_regulation of Gene_expression of IL1B 1 0.02 0.61 0.57
185 INT202961 MCRS1 Negative_regulation of STC2 1 0.00 1.63 0.57
186 INT56088 TGFB1 Positive_regulation of Transcription of SERPINE1 1 0.46 0.83 0.57
187 INT108387 IL1B Positive_regulation of Localization of MMP1 1 0.27 0.3 0.57
188 INT143938 Il1rn Negative_regulation of Il1b 1 0.04 0.52 0.57
189 INT185809 Binding of PDX1 and SPP1 1 0.02 1.69 0.57
190 INT60665 Il1b Regulation of Oprd1 1 0.05 0 0.57
191 INT58805 Il1b Negative_regulation of LH 1 0.24 0 0.56
192 INT333477 CXCL10 Positive_regulation of TH1L 1 0.14 0.32 0.56
193 INT201949 CXCL10 Positive_regulation of Phosphorylation of MAPK1 1 0.15 0.79 0.55
194 INT302645 ARSA Positive_regulation of Gene_expression of TGFB1 1 0.08 0.28 0.55
195 INT201944 CXCL10 Positive_regulation of Phosphorylation of AKT1 1 0.09 0.79 0.55
196 INT71943 Regulation of ZNF697 Negative_regulation of PTGS2 1 0.01 0.07 0.54
197 INT134488 Il1b Regulation of Oxt 1 0.30 0.08 0.54
198 INT129912 Skiv2l Negative_regulation of Gene_expression of PTGS2 1 0.00 0.87 0.54
199 INT204087 IL1B Positive_regulation of Gene_expression of LEP 1 0.09 2.6 0.54
200 INT161251 Ptgs2 Regulation of Mapk14 1 0.16 0.82 0.54

Single Events

The table below shows the top 100 pain related interactions that have been reported for response to vitamin D. They are ordered first by their pain relevance and then by number of times they were reported in response to vitamin D. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT34869 Negative_regulation of PTGS2 778 0.59 366.76 319.85
2 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97
3 INT50674 Gene_expression of PTGS2 459 0.78 253.33 118.51
4 INT10272 Gene_expression of Il1b 194 0.78 121.02 103.03
5 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9
6 INT5610 Positive_regulation of Insr 140 0.69 37.26 86.24
7 INT10274 Positive_regulation of Il1b 123 0.70 79.76 73.56
8 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35
9 INT6849 Localization of IL1B 229 0.81 112.56 69.63
10 INT15613 Negative_regulation of Ptgs2 160 0.59 71.08 65.08
11 INT39153 Positive_regulation of PTGS2 182 0.70 96.16 60.6
12 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18
13 INT46637 Gene_expression of CXCL10 172 0.78 121.94 57.74
14 INT52692 Gene_expression of Ptgs2 160 0.78 85.06 55.73
15 INT5034 Negative_regulation of Insr 100 0.55 28.08 54.5
16 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86
17 INT17915 Gene_expression of Insr 141 0.75 47.45 48.59
18 INT9233 Negative_regulation of Gene_expression of IL1B 114 0.59 56.99 41.82
19 INT5973 Regulation of IL1B 109 0.62 66.6 39.88
20 INT55135 Positive_regulation of Gene_expression of PTGS2 137 0.70 80.32 38.46
21 INT6484 Binding of IL1B 122 0.47 75.84 35.07
22 INT9347 Localization of Il1b 58 0.81 26.13 31.53
23 INT8691 Localization of Insr 85 0.80 9.27 30.32
24 INT52690 Positive_regulation of Ptgs2 65 0.68 39.51 30.02
25 INT5300 Regulation of Insr 54 0.60 11.33 29.26
26 INT10273 Positive_regulation of Gene_expression of Il1b 47 0.68 31.15 26.21
27 INT50490 Regulation of PTGS2 80 0.48 39.51 25.85
28 INT5948 Regulation of Il1b 44 0.60 22.8 25.4
29 INT10349 Negative_regulation of Il1b 48 0.58 25.53 24.24
30 INT110427 Gene_expression of Spp1 199 0.78 176.11 23.31
31 INT94335 Positive_regulation of CXCL10 71 0.58 50.69 23
32 INT14731 Positive_regulation of TGFB1 78 0.67 52.57 22.23
33 INT14733 Positive_regulation of Gene_expression of TGFB1 71 0.69 49.89 22.2
34 INT52693 Positive_regulation of Gene_expression of Ptgs2 57 0.70 25.51 21.18
35 INT17848 Binding of PTGS2 70 0.46 32.1 20.6
36 INT9237 Regulation of Gene_expression of IL1B 49 0.62 30.69 20.34
37 INT187513 Positive_regulation of Pla2g4a 5 0.62 34.09 18.22
38 INT12081 Localization of TGFB1 64 0.81 35.4 17.47
39 INT36054 Transcription of IL1B 53 0.72 32.64 17.31
40 INT195831 Phosphorylation of Pla2g4a 15 0.74 34.43 17.14
41 INT72188 Gene_expression of Cxcl10 22 0.65 12.93 15.35
42 INT36336 Gene_expression of Tgfb1 41 0.77 21.82 14.53
43 INT25266 Positive_regulation of Localization of IL1B 38 0.69 15.89 14.35
44 INT29170 Negative_regulation of Gene_expression of Il1b 25 0.59 16.36 13.68
45 INT92237 Positive_regulation of Gene_expression of CXCL10 43 0.70 43.67 13.65
46 INT19191 Negative_regulation of Localization of IL1B 35 0.58 15.19 13.63
47 INT14768 Negative_regulation of Positive_regulation of Insr 16 0.56 5.51 13.59
48 INT59080 Negative_regulation of Gene_expression of PTGS2 55 0.58 22.92 12.39
49 INT120828 Localization of CXCL10 29 0.68 18.01 12.17
50 INT37541 Gene_expression of SPP1 113 0.77 68.54 11.35
51 INT270238 Localization of Pla2g4a 1 0.72 17.99 11.35
52 INT6515 Gene_expression of BGLAP 110 0.75 45.13 10.81
53 INT52689 Regulation of Ptgs2 27 0.60 12.76 10.6
54 INT50196 Transcription of Il1b 25 0.69 19.08 10.43
55 INT85535 Negative_regulation of Gene_expression of Ptgs2 27 0.51 16.04 10.01
56 INT6516 Positive_regulation of BGLAP 45 0.67 26.61 9.9
57 INT69321 Regulation of Gene_expression of PTGS2 27 0.61 13.27 9.53
58 INT17250 Negative_regulation of BGLAP 35 0.57 21 8.26
59 INT50195 Positive_regulation of Positive_regulation of Il1b 12 0.67 7.41 7.64
60 INT52688 Transcription of Ptgs2 16 0.69 8.31 7.52
61 INT122901 Positive_regulation of Spp1 67 0.67 58.03 7.49
62 INT30920 Positive_regulation of Gene_expression of Insr 14 0.66 2.91 7.32
63 INT11378 Negative_regulation of Positive_regulation of IL1B 23 0.59 10.28 7.26
64 INT24622 Positive_regulation of Localization of Insr 15 0.69 0.32 6.85
65 INT36053 Positive_regulation of Positive_regulation of IL1B 22 0.70 11.41 6.84
66 INT90097 Localization of PTGS2 15 0.69 6.14 6.63
67 INT59079 Transcription of PTGS2 30 0.72 14.21 6.52
68 INT48954 Positive_regulation of Localization of Il1b 13 0.53 8.16 6.44
69 INT67130 Negative_regulation of Localization of Il1b 7 0.57 1.36 6.42
70 INT122902 Positive_regulation of Gene_expression of Spp1 54 0.70 56.3 6.33
71 INT67656 Positive_regulation of Positive_regulation of PTGS2 12 0.46 4.83 6.17
72 INT78955 Regulation of Gene_expression of Ptgs2 12 0.62 7.22 6.02
73 INT32611 Phosphorylation of Insr 13 0.80 4.18 5.77
74 INT14769 Positive_regulation of Positive_regulation of Insr 10 0.43 2.66 5.55
75 INT55578 Regulation of Gene_expression of Il1b 7 0.62 4.74 5.55
76 INT10705 Binding of Il1b 9 0.36 2.8 5.53
77 INT88935 Positive_regulation of SPP1 36 0.70 31.07 5.49
78 INT50197 Positive_regulation of Transcription of Il1b 11 0.50 8.95 5.41
79 INT89104 Binding of TGFB1 29 0.44 13.67 5.12
80 INT92234 Regulation of CXCL10 15 0.42 8.37 5.09
81 INT4864 Regulation of BGLAP 22 0.34 10.8 5.07
82 INT92236 Regulation of Gene_expression of CXCL10 6 0.42 7.12 4.92
83 INT10115 Gene_expression of INSR 31 0.75 11.98 4.86
84 INT16047 Negative_regulation of Positive_regulation of Il1b 11 0.57 5.27 4.66
85 INT68260 Localization of BGLAP 34 0.78 16.04 4.63
86 INT24620 Negative_regulation of Gene_expression of Insr 14 0.39 6.98 4.61
87 INT73309 Regulation of Negative_regulation of PTGS2 14 0.44 9.55 4.5
88 INT89103 Regulation of Gene_expression of TGFB1 15 0.56 8.11 4.37
89 INT51084 Binding of Insr 13 0.30 4.25 4.23
90 INT36335 Localization of Tgfb1 19 0.79 7.06 4.17
91 INT52616 Negative_regulation of Positive_regulation of PTGS2 13 0.43 4.95 4.13
92 INT19190 Regulation of Localization of IL1B 14 0.50 8.71 4.12
93 INT83035 Binding of INSR 16 0.47 9.29 4.11
94 INT64864 Gene_expression of PLA2G4A 18 0.77 10.45 4.09
95 INT127667 Positive_regulation of Localization of CXCL10 5 0.59 5.89 4.09
96 INT202978 Gene_expression of STC2 11 0.50 13.46 4.06
97 INT97128 Localization of SPP1 32 0.80 21.75 4.02
98 INT6513 Positive_regulation of Gene_expression of BGLAP 24 0.67 11.69 3.96
99 INT100491 Positive_regulation of Cxcl10 8 0.41 3.97 3.93
100 INT148085 Binding of CXCL10 14 0.32 10.22 3.81
101 INT202976 Positive_regulation of STC2 1 0.04 9.73 3.78
102 INT162125 Gene_expression of Pla2g4a 4 0.54 7.69 3.75
103 INT12083 Regulation of TGFB1 22 0.53 15.4 3.6
104 INT51848 Transcription of TGFB1 17 0.69 9.57 3.53
105 INT56300 Negative_regulation of Gene_expression of TGFB1 13 0.41 4.87 3.5
106 INT10116 Localization of INSR 11 0.57 5.43 3.48
107 INT94337 Transcription of CXCL10 11 0.49 6.66 3.46
108 INT14060 Negative_regulation of Negative_regulation of Insr 6 0.53 3.53 3.44
109 INT136791 Negative_regulation of Spp1 24 0.59 23.6 3.33
110 INT202983 Regulation of STC2 1 0.03 11.98 3.33
111 INT202977 Binding of STC2 1 0.02 8.53 3.31
112 INT69216 Positive_regulation of Tgfb1 14 0.49 5.84 3.29
113 INT85147 Positive_regulation of Gene_expression of Tgfb1 12 0.46 7.29 3.24
114 INT270224 Positive_regulation of Positive_regulation of Pla2g4a 1 0.62 6.63 3.22
115 INT185487 Localization of Cxcl10 6 0.61 3.21 3.21
116 INT85149 Negative_regulation of Gene_expression of Tgfb1 11 0.42 4.73 3.19
117 INT38276 Negative_regulation of CXCL10 10 0.42 9.26 3.19
118 INT185482 Binding of Cxcl10 5 0.30 3.76 3.13
119 INT52694 Negative_regulation of Positive_regulation of Ptgs2 9 0.43 4.72 3.11
120 INT88130 Gene_expression of Spp1 13 0.74 12.96 3.07
121 INT91341 Negative_regulation of Gene_expression of BGLAP 17 0.55 4.91 3.02
122 INT112667 Negative_regulation of Tgfb1 9 0.58 2.72 2.97
123 INT9130 Negative_regulation of TGFB1 16 0.41 12.21 2.92
124 INT91342 Negative_regulation of Negative_regulation of BGLAP 2 0.55 1.39 2.88
125 INT39908 Gene_expression of Cyp27b1 16 0.69 4.8 2.83
126 INT6479 Negative_regulation of Binding of IL1B 10 0.43 5.1 2.78
127 INT112147 Positive_regulation of Negative_regulation of Il1b 3 0.49 3.42 2.77
128 INT68505 Positive_regulation of Negative_regulation of PTGS2 8 0.49 2.26 2.76
129 INT10350 Negative_regulation of Regulation of Il1b 3 0.41 0.58 2.69
130 INT11379 Positive_regulation of Negative_regulation of IL1B 9 0.49 7.2 2.64
131 INT15144 Protein_catabolism of IL1B 11 0.92 4.67 2.58
132 INT100492 Positive_regulation of Gene_expression of Cxcl10 5 0.49 1.71 2.56
133 INT23527 Negative_regulation of Localization of Insr 10 0.39 2.58 2.5
134 INT17846 Binding of Ptgs2 8 0.32 4.66 2.48
135 INT270235 Negative_regulation of Phosphorylation of Pla2g4a 1 0.39 3.4 2.34
136 INT78958 Regulation of Negative_regulation of Ptgs2 6 0.42 2.61 2.3
137 INT176517 Negative_regulation of Gene_expression of Spp1 18 0.59 15.31 2.28
138 INT61225 Positive_regulation of Cyp27b1 8 0.31 2.32 2.24
139 INT36055 Positive_regulation of Transcription of IL1B 9 0.49 6.24 2.21
140 INT152076 Negative_regulation of Pla2g4a 3 0.55 3.22 2.21
141 INT222225 Regulation of Cxcl10 4 0.23 2.59 2.19
142 INT24621 Regulation of Gene_expression of Insr 9 0.42 2.68 2.18
143 INT91340 Regulation of Localization of BGLAP 5 0.58 2.82 2.14
144 INT195828 Positive_regulation of Phosphorylation of Pla2g4a 3 0.45 5.05 2.12
145 INT73906 Regulation of Transcription of IL1B 5 0.56 3.46 2.1
146 INT12086 Regulation of Localization of TGFB1 4 0.43 1.65 2.09
147 INT31006 Regulation of Localization of Insr 7 0.50 0.2 2.05
148 INT186893 Binding of BGLAP 10 0.37 6.19 2.02
149 INT55035 Negative_regulation of Negative_regulation of Il1b 4 0.43 1.46 2.02
150 INT168275 Phosphorylation of Il1b 1 0.79 2.39 2.01
151 INT176510 Binding of Spp1 21 0.42 22.1 2
152 INT97579 Negative_regulation of Localization of PTGS2 2 0.08 2.37 1.99
153 INT171323 Phosphorylation of IL1B 5 0.57 4.13 1.94
154 INT176516 Localization of Spp1 28 0.76 19.39 1.9
155 INT52691 Positive_regulation of Transcription of Ptgs2 5 0.44 3 1.9
156 INT29577 Negative_regulation of Cyp27b1 5 0.37 2.41 1.88
157 INT74824 Positive_regulation of Transcription of TGFB1 6 0.67 2.58 1.84
158 INT131916 Negative_regulation of ALPL 10 0.42 9.33 1.8
159 INT14246 Regulation of Positive_regulation of IL1B 7 0.44 3.04 1.77
160 INT218303 Protein_catabolism of INSR 3 0.29 0.67 1.73
161 INT232645 Transcription of INSR 2 0.09 1.19 1.71
162 INT116498 Negative_regulation of Negative_regulation of IL1B 7 0.41 3.08 1.7
163 INT222234 Negative_regulation of Gene_expression of Cxcl10 1 0.35 1.23 1.67
164 INT133311 Binding of SPP1 10 0.37 9.47 1.65
165 INT86712 Regulation of Gene_expression of Tgfb1 2 0.15 2.03 1.65
166 INT37838 Regulation of Cyp27b1 4 0.27 0.67 1.61
167 INT181316 Positive_regulation of ALPL 5 0.65 1.65 1.6
168 INT88136 Positive_regulation of Gene_expression of Spp1 8 0.66 4.5 1.57
169 INT73901 Negative_regulation of Transcription of IL1B 3 0.53 0.46 1.57
170 INT91773 Positive_regulation of PLA2G4A 10 0.50 4.4 1.54
171 INT91764 Positive_regulation of Gene_expression of PLA2G4A 8 0.69 5.43 1.52
172 INT110992 Positive_regulation of Positive_regulation of TGFB1 4 0.50 3.01 1.51
173 INT270223 Negative_regulation of Localization of Pla2g4a 1 0.39 1.83 1.5
174 INT128865 Regulation of Positive_regulation of RXRA 1 0.08 0.64 1.48
175 INT88934 Regulation of SPP1 9 0.54 6.94 1.47
176 INT128863 Positive_regulation of RXRA 1 0.12 0.63 1.47
177 INT104250 Positive_regulation of Gene_expression of SPP1 17 0.69 13.22 1.44
178 INT190768 Regulation of Positive_regulation of Ptgs2 1 0.04 1.2 1.41
179 INT12085 Positive_regulation of Localization of TGFB1 7 0.42 4.9 1.4
180 INT86823 Regulation of Transcription of PTGS2 3 0.19 1.48 1.4
181 INT262123 Gene_expression of Cyp24a1 17 0.67 6.67 1.38
182 INT135658 Phosphorylation of Ptgs2 2 0.23 1.39 1.34
183 INT88133 Positive_regulation of Spp1 8 0.66 10.07 1.33
184 INT195060 Gene_expression of ALPL 9 0.73 4.82 1.3
185 INT173892 Phosphorylation of TGFB1 8 0.79 2.63 1.3
186 INT10117 Positive_regulation of INSR 10 0.43 4.71 1.22
187 INT173114 Positive_regulation of Binding of IL1B 6 0.49 2.56 1.22
188 INT118606 Protein_catabolism of CXCL10 2 0.86 0.98 1.22
189 INT179372 Positive_regulation of Localization of PTGS2 2 0.38 0.35 1.21
190 INT59078 Positive_regulation of Transcription of PTGS2 5 0.69 2.36 1.17
191 INT106339 Positive_regulation of Phosphorylation of Insr 1 0.49 0 1.12
192 INT62981 Protein_catabolism of PTGS2 5 0.78 1.09 1.11
193 INT201954 Positive_regulation of Protein_catabolism of CXCL10 1 0.41 0.7 1.1
194 INT64862 Negative_regulation of Negative_regulation of PTGS2 3 0.36 0.76 1.09
195 INT70505 Positive_regulation of Positive_regulation of Ptgs2 4 0.49 2.22 1.08
196 INT32354 Negative_regulation of Regulation of Insr 3 0.33 0.13 1.08
197 INT64863 Localization of PLA2G4A 9 0.44 3.33 1.07
198 INT83647 Negative_regulation of Negative_regulation of Ptgs2 1 0.28 1.97 1.05
199 INT217341 Negative_regulation of Gene_expression of CXCL10 6 0.25 4.97 1.04
200 INT9348 Regulation of Localization of Il1b 2 0.27 0.14 1.04
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