GO:0033344

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Name cholesterol efflux
Categary Process
Go Slim No
Go Link GO:0033344
Unique Molecular Interactions 525
Total Molecular Interactions 765
Total Single Events 4925
Pain Genes Associated 30

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cholesterol efflux. They are ordered first by their pain relevance and then by number of times they were reported for cholesterol efflux. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT297332 Apoe Negative_regulation of Gene_expression of Mpz 1 0.02 1.09 0.87
2 INT208354 Binding of Apoe and Hdl1 12 0.13 8.37 0.77
3 INT284481 Binding of ABCA1 and Ighg1 1 0.00 1.39 0.7
4 INT231534 Binding of JAK1 and SOAT1 1 0.01 0.6 0.64
5 INT297344 Apoe Regulation of Binding of Alms1 1 0.08 1.1 0.61
6 INT297340 Apoe Regulation of Binding of Smo 1 0.10 1.1 0.6
7 INT297331 Apoe Negative_regulation of Gene_expression of Il6 1 0.14 0.61 0.57
8 INT278688 MTX1 Negative_regulation of Positive_regulation of SOAT1 1 0.04 0.69 0.54
9 INT18115 Binding of NPC1 and Oprd1 1 0.11 0 0.54
10 INT125699 CR1 Negative_regulation of Positive_regulation of ABCA1 1 0.03 0.64 0.53
11 INT254761 Igh-Dex Positive_regulation of Apoe 1 0.00 0.08 0.52
12 INT345308 Binding of ABCA1 and TIMP2 1 0.00 0.21 0.52
13 INT187114 TIMP2 Negative_regulation of ABCA1 1 0.02 0.28 0.51
14 INT187108 TIMP1 Negative_regulation of ABCA1 1 0.02 0.28 0.51
15 INT116862 Apoe Positive_regulation of Il10 1 0.30 0.69 0.5
16 INT116863 Apoe Negative_regulation of Hand1 1 0.37 0.69 0.5
17 INT254768 DNMT1 Positive_regulation of Gene_expression of Apoe 1 0.02 0.05 0.49
18 INT220741 Binding of EGFR and SOAT1 1 0.02 0.37 0.49
19 INT352892 Binding of CAV1 and ITGA2 1 0.20 1.61 0.47
20 INT197496 Binding of Apoe and Lrp1 4 0.22 2.32 0.46
21 INT193480 Binding of ABCA1 and IRF6 1 0.00 1.08 0.46
22 INT69637 Binding of CAV1 and Zfp354a 1 0.00 0 0.46
23 INT136749 COX5A Positive_regulation of Gene_expression of SCARB1 1 0.52 0.36 0.45
24 INT307781 Apoa1 Positive_regulation of LCAT 1 0.76 1.19 0.45
25 INT142608 Apoe Regulation of Gene_expression of Il6 1 0.25 1.01 0.44
26 INT213027 Binding of Apoa1 and Scarb1 6 0.09 7.52 0.43
27 INT307780 Apoa1 Positive_regulation of Soat1 1 0.04 1.14 0.42
28 INT254760 Igh-Dex Positive_regulation of Gene_expression of Apoe 1 0.00 0 0.42
29 INT329085 Csf2 Positive_regulation of Apoe 1 0.00 1.23 0.42
30 INT234608 Socs3 Negative_regulation of SOAT1 1 0.01 0.54 0.39
31 INT237369 SOAT1 Negative_regulation of Phosphorylation of JAK1 1 0.00 0 0.38
32 INT231535 Binding of JAK2 and SOAT1 1 0.01 0.3 0.35
33 INT28006 NPC1 Negative_regulation of Positive_regulation of Rps6ka1 1 0.01 0.37 0.33
34 INT28005 NPC1 Negative_regulation of Rps6ka1 1 0.01 0.45 0.32
35 INT224131 Binding of CAV1 and Agtr1a 1 0.00 0.08 0.3
36 INT297335 Binding of Apoc3 and Hdl1 1 0.00 0.92 0.29
37 INT303949 LEPR Positive_regulation of SOAT1 1 0.01 0.22 0.28
38 INT254759 Igh-Dex Positive_regulation of Localization of Apoe 1 0.00 0.32 0.28
39 INT254769 Binding of LDLR and Apoe 1 0.03 0 0.28
40 INT141870 Binding of Slc2a4 and Cav1 1 0.36 0.38 0.28
41 INT297338 Apoe Regulation of Gnb5 1 0.06 1.12 0.27
42 INT213029 Positive_regulation of Binding of Apoa1 and Scarb1 1 0.09 3.38 0.27
43 INT307207 Ppara Positive_regulation of Apoa2 1 0.10 0.94 0.25
44 INT130056 PPARG Positive_regulation of CAV1 1 0.02 0.53 0.25
45 INT254772 DNMT1 Positive_regulation of Apoe 1 0.02 0 0.25
46 INT186191 Binding of SCARB1 and TBP 1 0.03 2.57 0.24
47 INT78293 Binding of Apoe and Ldlr 1 0.20 0.25 0.24
48 INT78295 Binding of Ptpra and Apoe 1 0.42 0.25 0.24
49 INT297334 Gnb5 Regulation of Apoe 1 0.09 0.83 0.24
50 INT239337 Abca1 Positive_regulation of RCT 1 0.07 3.11 0.24
51 INT78294 Negative_regulation of Binding of Ptpra and Apoe 1 0.48 0.25 0.24
52 INT254773 PPARA Positive_regulation of Gene_expression of Apoe 1 0.01 0.07 0.24
53 INT78292 Negative_regulation of Binding of Apoe and Ldlr 1 0.23 0.25 0.24
54 INT305798 Binding of APOA1 and OxP-11D 1 0.02 0.45 0.23
55 INT254774 DNMT1 Positive_regulation of Localization of Apoe 1 0.01 0.31 0.23
56 INT288582 Binding of Cav1 and Kcnma1 1 0.11 0 0.22
57 INT220528 Ugt1a6b Positive_regulation of Cav1 1 0.01 1.31 0.22
58 INT303606 Binding of IL18 and SOAT1 1 0.05 0.52 0.22
59 INT234724 Binding of NPC1 and Cxcl1 1 0.00 0.33 0.21
60 INT189321 Binding of Apoa1 and Hdlcl1 1 0.00 0.68 0.2
61 INT134494 Binding of APOE and Alb 1 0.11 0.45 0.2
62 INT300193 Binding of APOA1 and INSL4 1 0.01 2.17 0.18
63 INT239316 Nr1h2 Positive_regulation of Transcription of Abca1 1 0.15 0.67 0.18
64 INT308518 HSP90B1 Positive_regulation of Positive_regulation of SOAT1 1 0.00 0.65 0.18
65 INT335046 PPARA Positive_regulation of Gene_expression of ABCA1 1 0.33 0.25 0.18
66 INT207345 PTGDS Negative_regulation of Gene_expression of ABCA1 1 0.21 0 0.17
67 INT220520 Ugt1a6b Positive_regulation of Gene_expression of Cav1 1 0.01 0.81 0.17
68 INT207359 ZNF398 Negative_regulation of ABCA1 1 0.01 0 0.17
69 INT208360 Binding of Abca1 and Apoe 1 0.15 0.74 0.17
70 INT197499 Binding of Apoe and Tfrc 1 0.14 1.54 0.17
71 INT207344 PTGER2 Negative_regulation of Gene_expression of ABCA1 1 0.04 0 0.17
72 INT207350 TBXA2R Regulation of Gene_expression of ABCA1 1 0.10 0 0.17
73 INT122528 Apoe Regulation of Eno2 1 0.05 0.29 0.16
74 INT122529 Apoe Regulation of S100B 1 0.18 0.29 0.16
75 INT43510 Apoa2 Positive_regulation of Localization of POMC 1 0.03 0 0.16
76 INT207338 Negative_regulation of CPOX Negative_regulation of ABCA1 1 0.11 0 0.16
77 INT297345 Apoe Negative_regulation of Csf2 1 0.17 0.66 0.16
78 INT86216 Hpd Regulation of NPC1 1 0.02 0.93 0.15
79 INT186380 Binding of SOAT1 and Stat6 1 0.02 0.11 0.15
80 INT329850 APOA5 Negative_regulation of Transcription of APOC3 1 0.24 0.85 0.15
81 INT155644 Binding of CAV1 and HSD11B1 1 0.39 0.77 0.15
82 INT335459 ABCA1 Positive_regulation of ITPR3 1 0.00 0 0.15
83 INT87110 Apom Negative_regulation of Pde1a 1 0.00 0 0.15
84 INT156531 Binding of ABCA1 and HSD11B1 1 0.22 1.06 0.14
85 INT207360 PTGDS Negative_regulation of Negative_regulation of ABCA1 1 0.25 0 0.14
86 INT344707 Scarb1 Positive_regulation of Positive_regulation of Hdl1 1 0.14 0.88 0.14
87 INT207337 PTGER2 Negative_regulation of Negative_regulation of ABCA1 1 0.04 0 0.14
88 INT315030 Binding of Cav1 and Tmie 1 0.03 0.25 0.14
89 INT332256 Pdgfa Positive_regulation of SOAT1 1 0.01 0.51 0.14
90 INT207353 ZNF398 Regulation of ABCA1 1 0.00 0 0.14
91 INT323877 LEP Positive_regulation of SOAT1 1 0.20 1.26 0.14
92 INT297333 Apoe Negative_regulation of Positive_regulation of Tlr4 1 0.10 1.02 0.14
93 INT297343 Binding of Apoe and Tlr4 1 0.09 0.94 0.14
94 INT315032 Binding of Cav1 and Ryr1 1 0.27 0.2 0.14
95 INT297339 Tlr4 Negative_regulation of Gene_expression of Apoe 1 0.10 0.73 0.13
96 INT262618 Binding of SOAT1 and Kras 1 0.00 0.81 0.12
97 INT344705 Nr1h2 Regulation of Scarb1 1 0.04 1.53 0.12
98 INT344706 Nr1h2 Regulation of Abca1 1 0.03 2.39 0.12
99 INT33752 Apoa2 Regulation of Localization of POMC 1 0.06 0 0.12
100 INT344713 Nr1h2 Regulation of Abcg1 1 0.03 2.39 0.12
101 INT182481 Binding of Cav1 and Ighg2b 1 0.10 0 0.12
102 INT182482 Binding of Cav1 and Cxcl16 1 0.07 0 0.12
103 INT33750 Apoa2 Regulation of Agt 1 0.07 0 0.12
104 INT33751 Apoa2 Positive_regulation of Positive_regulation of POMC 1 0.09 0 0.11
105 INT2458 Apoa2 Positive_regulation of Localization of Avp 1 0.10 0 0.11
106 INT311871 Cav1 Regulation of Mch 1 0.01 0.24 0.11
107 INT213042 Apoa1 Positive_regulation of Nos3 1 0.10 2.17 0.11
108 INT293236 IDO1 Regulation of ABCA1 1 0.00 0 0.11
109 INT208361 Positive_regulation of Binding of Apoe and Hdl1 1 0.12 1.22 0.1
110 INT16860 Abcg5 Negative_regulation of Maob 1 0.10 0 0.1
111 INT220517 Negative_regulation of Ugt1a6b Positive_regulation of Cav1 1 0.01 0.35 0.1
112 INT323879 LEP Regulation of SOAT1 1 0.15 1.15 0.1
113 INT297346 Apoe Negative_regulation of Localization of TNF 1 0.48 0.26 0.1
114 INT305780 Binding of APOA1 and LRCH2 1 0.00 0.19 0.1
115 INT282094 Apoa2 Negative_regulation of BCL2 1 0.06 1.15 0.09
116 INT194742 SOAT1 Positive_regulation of Positive_regulation of IK 1 0.00 0.1 0.09
117 INT42224 ABCA1 Positive_regulation of CYBB 1 0.01 0 0.09
118 INT302977 Binding of Cav1 and Smpd2 1 0.08 0.71 0.09
119 INT220511 Cav1 Negative_regulation of Transcription of Ccnd1 1 0.03 0.83 0.09
120 INT42225 Binding of ABCA1 and DECR1 1 0.02 0 0.08
121 INT355021 Cntf Positive_regulation of SOAT1 1 0.02 0.7 0.08
122 INT300192 Gene_expression of APOA1 Positive_regulation of HSD11B1 1 0.16 1.08 0.08
123 INT205135 Binding of APOE and APP 1 0.05 0.35 0.08
124 INT309159 Binding of Cav1 and Positive_regulation of Localization of Esr1 1 0.04 0 0.08
125 INT201543 Binding of NPC1 and RNASE1 1 0.07 1.33 0.08
126 INT355020 Lif Positive_regulation of SOAT1 1 0.02 0.7 0.08
127 INT43121 Apoa2 Regulation of Smc1b 1 0.02 0 0.08
128 INT300641 Binding of APOE and CRP 1 0.41 0.81 0.07
129 INT297330 Apoe Positive_regulation of Gene_expression of Nos2 1 0.26 0.34 0.07
130 INT190885 Binding of Apoa2 and Hdl1 1 0.02 0.73 0.07
131 INT289258 Binding of ABCA1 and Il6ra 1 0.00 0.33 0.07
132 INT308665 Binding of Apoe and Gopc 1 0.02 0.49 0.07
133 INT308663 Apoe Regulation of Car2 1 0.02 0.44 0.07
134 INT279652 PPARA Positive_regulation of Gene_expression of Apoa1 1 0.00 0.75 0.07
135 INT50078 Binding of APOE and NPPA 1 0.30 0.42 0.07
136 INT326067 APOA1 Positive_regulation of Localization of APOE 1 0.61 4.22 0.07
137 INT262175 Nr1i2 Positive_regulation of Gene_expression of Abca1 1 0.24 0.21 0.06
138 INT262187 Nr1i2 Positive_regulation of Gene_expression of Abcg1 1 0.24 0.21 0.06
139 INT293233 IDO1 Positive_regulation of ABCA1 1 0.01 0 0.06
140 INT186188 Binding of SCARB1 and PDZK1 1 0.53 0.54 0.05
141 INT339583 Binding of ABCA1 and RPE 1 0.03 1.38 0.05
142 INT212440 STAT3 Regulation of Phosphorylation of SOAT1 1 0.11 1.42 0.05
143 INT183853 Gene_expression of CAV1 Negative_regulation of Positive_regulation of MAPK1 1 0.28 0.25 0.05
144 INT335047 PPARA Positive_regulation of Gene_expression of APOA1 1 0.20 0.42 0.05
145 INT339587 Positive_regulation of Binding of ABCA1 and RPE 1 0.04 1.38 0.05
146 INT188432 Negative_regulation of Binding of ABCA1 and IL6 1 0.02 0.47 0.05
147 INT239348 Binding of Apoa1 and Hdl1 1 0.03 3.34 0.05
148 INT296023 Positive_regulation of Apoa2 Negative_regulation of APOA1 1 0.50 0.35 0.05
149 INT296024 Apoa2 Negative_regulation of CETP 1 0.39 0.35 0.05
150 INT186185 Binding of SCARB1 and SCARB2 1 0.22 0.58 0.05
151 INT188431 Binding of ABCA1 and IL6 1 0.02 0.47 0.05
152 INT251468 Binding of APOE and DBT 1 0.03 1.18 0.05
153 INT201535 Binding of NPC1 and XRCC1 1 0.26 1.6 0.05
154 INT43124 Apoa2 Positive_regulation of Positive_regulation of NA 1 0.07 0 0.05
155 INT296025 Apoa2 Negative_regulation of APOA1 1 0.47 0.35 0.05
156 INT307282 Binding of PMP2 and NPC2 1 0.21 0.08 0.04
157 INT208353 Binding of Apoc4 and Apoc3 1 0.00 2.56 0.04
158 INT236722 Ppara Positive_regulation of Binding of Apoa1 1 0.10 0.18 0.04
159 INT325027 Apoc3 Negative_regulation of Pnlip 1 0.01 1.02 0.04
160 INT208356 Hdl1 Positive_regulation of Apoe 1 0.12 1.25 0.04
161 INT186187 LDLR Regulation of Gene_expression of SCARB1 1 0.17 1.71 0.04
162 INT235551 Gene_expression of Hras1 Negative_regulation of Positive_regulation of Apoe 1 0.03 0.57 0.04
163 INT208357 Hdl1 Positive_regulation of Localization of Apoe 1 0.12 1.26 0.04
164 INT325026 Apoc3 Negative_regulation of Lpl 1 0.03 1.01 0.04
165 INT288908 Apoa1 Positive_regulation of Gene_expression of HSD11B1 1 0.03 0.53 0.04
166 INT325025 Apoa2 Positive_regulation of Hdl1 1 0.05 1.03 0.04
167 INT208350 Positive_regulation of Hdl1 Positive_regulation of Apoe 1 0.12 1.27 0.04
168 INT290181 Binding of APOE and PLTP 1 0.17 1.61 0.04
169 INT290375 Binding of Scarb1 and Gopc 1 0.15 0.29 0.04
170 INT247439 Binding of APOA1 and HSD11B1 3 0.32 5.01 0.03
171 INT213002 Binding of Scarb1 and Trib3 1 0.00 1.02 0.03
172 INT194483 Binding of Apoe and Chol1 1 0.24 0.51 0.03
173 INT239333 Abcg1 Positive_regulation of RCT 1 0.06 1.29 0.03
174 INT220512 Cav1 Regulation of Positive_regulation of Cdkn1b 1 0.06 0.85 0.03
175 INT213011 Binding of Scarb1 and Hdl1 1 0.13 0.96 0.03
176 INT230136 OSBPL8 Regulation of Binding of ABCA1 1 0.07 0.17 0.03
177 INT208352 Apoe Regulation of Localization of Em 1 0.04 1.15 0.03
178 INT186186 LDLR Regulation of SCARB1 1 0.08 0.65 0.03
179 INT207343 Negative_regulation of CPOX Negative_regulation of Gene_expression of ABCA1 1 0.09 0 0.03
180 INT194481 Binding of Apoe and Apob 1 0.07 0.51 0.03
181 INT239345 Apoa1 Positive_regulation of RCT 1 0.02 1.15 0.03
182 INT308658 Binding of Apoa2 and Apoe 1 0.17 0.15 0.03
183 INT183896 Gene_expression of CAV1 Negative_regulation of Positive_regulation of Racgap1 1 0.01 0.64 0.03
184 INT247155 Binding of Phb2 and Scarb1 1 0.01 0.33 0
185 INT332978 ACOX1 Negative_regulation of Transcription of Apoc3 1 0.00 0.98 0
186 INT284392 Binding of ABCA1 and Vegfa 1 0.00 0.71 0
187 INT201539 Binding of NPC1 and THY1 1 0.36 1.28 0
188 INT229927 CD59 Negative_regulation of Binding of ABCA1 1 0.01 0 0
189 INT351167 CAV1 Negative_regulation of Ppp2r1a 1 0.08 1.5 0
190 INT186190 OLR1 Positive_regulation of SCARB1 1 0.01 0.67 0
191 INT341487 Binding of APOE and TLR2 1 0.00 0.3 0
192 INT10903 Apoa2 Positive_regulation of Nppb 1 0.08 0.17 0
193 INT239332 Hdl1 Positive_regulation of Gene_expression of Apoa1 1 0.04 0.84 0
194 INT247441 Binding of APOC3 and SNRNP70 1 0.04 0.26 0
195 INT229923 Binding of ABCA1 and C9 1 0.00 0.74 0
196 INT288584 Cav1 Regulation of Gene_expression of Kcnma1 1 0.14 0 0
197 INT288594 Regulation of Binding of CAV1 and Kcnma1 1 0.01 0 0
198 INT288588 Binding of Cav1 and Neu3 1 0.01 0 0
199 INT326065 APOE Positive_regulation of LCAT 1 0.53 0.84 0
200 INT183895 CAV1 Regulation of Positive_regulation of Racgap1 1 0.01 0.37 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for cholesterol efflux. They are ordered first by their pain relevance and then by number of times they were reported in cholesterol efflux. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT116861 Gene_expression of Apoe 182 0.78 100.41 27.26
2 INT86698 Gene_expression of Cav1 38 0.78 16.37 11.75
3 INT36453 Binding of ABCA1 48 0.45 19.9 10.84
4 INT28312 Gene_expression of ABCA1 85 0.72 37.69 9.27
5 INT39457 Positive_regulation of SOAT1 32 0.67 22.8 8.28
6 INT8579 Gene_expression of Apoa1 13 0.76 35.89 7.21
7 INT197493 Localization of Apoe 61 0.79 27.48 7.06
8 INT142264 Positive_regulation of Apoe 47 0.50 26.35 6.94
9 INT19146 Negative_regulation of Apoa2 19 0.36 5.34 6.73
10 INT182351 Positive_regulation of Gene_expression of Apoe 38 0.50 19.78 6.72
11 INT63042 Binding of Apoe 59 0.48 31.23 5.88
12 INT186063 Phosphorylation of SOAT1 29 0.28 11.77 5.34
13 INT74614 Positive_regulation of Apoa1 16 0.68 23.95 5.04
14 INT3476 Phosphorylation of Npc1 7 0.48 0 4.84
15 INT136754 Gene_expression of SCARB1 64 0.77 43.28 4.82
16 INT2848 Localization of ABCA1 23 0.70 10.64 4.73
17 INT55758 Positive_regulation of Apoe 15 0.70 11.71 4.69
18 INT181886 Gene_expression of Apoa1 40 0.64 40.53 4.56
19 INT2453 Positive_regulation of Apoa2 20 0.54 3.49 4.08
20 INT76227 Binding of NPC1 30 0.41 32.31 4.05
21 INT141443 Phosphorylation of Cav1 6 0.82 4.39 4.03
22 INT153666 Gene_expression of CAV1 156 0.77 120.99 3.9
23 INT15033 Gene_expression of Apoe 18 0.78 14.97 3.75
24 INT104624 Negative_regulation of Apoe 26 0.59 19.25 3.71
25 INT52047 Gene_expression of APOE 50 0.78 34.75 3.52
26 INT18670 Negative_regulation of ABCA1 16 0.54 5.8 3.39
27 INT72141 Binding of Apoe 11 0.37 10.91 3.27
28 INT28130 Positive_regulation of ABCA1 18 0.61 7.08 3.22
29 INT97710 Localization of Apoe 1 0.79 7.18 3.2
30 INT10830 Regulation of Apoa1 11 0.44 15.1 3.04
31 INT10556 Regulation of Apoa2 5 0.44 0.51 2.8
32 INT59342 Negative_regulation of NPC1 20 0.44 20.21 2.79
33 INT86703 Positive_regulation of Gene_expression of Cav1 7 0.70 3.58 2.73
34 INT50080 Binding of APOE 38 0.45 29.61 2.67
35 INT21712 Positive_regulation of APOA1 32 0.67 21.64 2.64
36 INT97713 Negative_regulation of Apoe 4 0.59 4.57 2.52
37 INT190081 Gene_expression of Abca1 21 0.65 18.18 2.45
38 INT3475 Regulation of Phosphorylation of Npc1 3 0.36 0 2.45
39 INT181880 Positive_regulation of Apoa1 19 0.66 21.19 2.43
40 INT231557 Positive_regulation of Phosphorylation of SOAT1 7 0.22 5.22 2.33
41 INT2452 Localization of Apoa2 9 0.55 0 2.3
42 INT208344 Positive_regulation of Localization of Apoe 22 0.48 9.6 2.27
43 INT142265 Regulation of Apoe 20 0.60 9.52 2.23
44 INT136614 Positive_regulation of Cav1 5 0.46 2.28 2.23
45 INT84060 Regulation of Apoe 4 0.62 3.33 2.05
46 INT49313 Positive_regulation of Gene_expression of Apoa1 3 0.68 9.55 2.01
47 INT112089 Gene_expression of Cav1 73 0.75 23.8 1.97
48 INT190883 Gene_expression of Apoc3 16 0.38 14.18 1.93
49 INT78960 Binding of SOAT1 9 0.36 2.56 1.92
50 INT22863 Negative_regulation of Apoa1 10 0.57 10.68 1.86
51 INT169862 Regulation of NPC1 13 0.53 13.61 1.84
52 INT39458 Negative_regulation of SOAT1 8 0.57 10.56 1.83
53 INT21813 Gene_expression of Apoa2 10 0.61 3.68 1.81
54 INT207370 Negative_regulation of Gene_expression of ABCA1 1 0.54 2.75 1.78
55 INT136752 Positive_regulation of Gene_expression of SCARB1 5 0.69 10.63 1.76
56 INT141444 Positive_regulation of Phosphorylation of Cav1 1 0.70 1.76 1.69
57 INT72676 Gene_expression of APOA1 34 0.75 34.15 1.67
58 INT156484 Binding of Apoa1 4 0.47 6.78 1.63
59 INT135955 Positive_regulation of Cav1 17 0.48 7.73 1.61
60 INT96814 Negative_regulation of APOE 13 0.59 10.64 1.61
61 INT42585 Positive_regulation of Phosphorylation of Npc1 3 0.19 0 1.59
62 INT39459 Gene_expression of SOAT1 10 0.75 7.62 1.52
63 INT181881 Positive_regulation of Gene_expression of Apoa1 13 0.48 14.31 1.45
64 INT18114 Gene_expression of NPC1 45 0.66 57.85 1.44
65 INT100540 Localization of SOAT1 9 0.78 2.67 1.42
66 INT217388 Negative_regulation of Gene_expression of Apoe 11 0.59 6.07 1.4
67 INT155845 Transcription of SOAT1 6 0.67 2.89 1.4
68 INT181882 Localization of Apoa1 8 0.71 7.94 1.37
69 INT97716 Transcription of Apoe 3 0.53 2.61 1.36
70 INT141862 Binding of Cav1 11 0.36 1.32 1.25
71 INT97715 Regulation of Gene_expression of Apoe 3 0.62 1.98 1.23
72 INT113336 Positive_regulation of Gene_expression of Apoe 3 0.70 1.79 1.23
73 INT60291 Regulation of SOAT1 9 0.19 3.99 1.17
74 INT139764 Negative_regulation of CAV1 10 0.58 6.57 1.14
75 INT181879 Negative_regulation of Apoa1 8 0.55 8.18 1.11
76 INT176183 Gene_expression of Abcg5 1 0.77 5.01 1.08
77 INT239302 Positive_regulation of Gene_expression of Abca1 9 0.32 9.1 1.06
78 INT217390 Negative_regulation of Positive_regulation of Apoe 3 0.37 1.95 1.05
79 INT21546 Regulation of ABCA1 16 0.40 4.21 1.04
80 INT97714 Negative_regulation of Localization of Apoe 1 0.58 1.83 0.97
81 INT136613 Negative_regulation of Cav1 2 0.57 2.28 0.96
82 INT211557 Gene_expression of Scarb1 30 0.75 5.03 0.94
83 INT106952 Positive_regulation of NPC1 23 0.43 22.9 0.94
84 INT153670 Positive_regulation of Gene_expression of CAV1 26 0.69 44.27 0.92
85 INT294479 Gene_expression of Scarb1 1 0.02 3.08 0.9
86 INT180451 Positive_regulation of Apoa2 15 0.67 12.65 0.89
87 INT72672 Positive_regulation of Gene_expression of APOA1 4 0.67 3.81 0.89
88 INT141442 Negative_regulation of Phosphorylation of Cav1 1 0.59 0.94 0.87
89 INT181885 Binding of Apoa1 7 0.35 5.66 0.84
90 INT190089 Binding of Abca1 5 0.36 2.21 0.83
91 INT79941 Negative_regulation of Npc1 9 0.59 3.97 0.82
92 INT142597 Regulation of Binding of Apoe 1 0.34 2.21 0.8
93 INT112090 Negative_regulation of Gene_expression of Cav1 8 0.57 3.5 0.78
94 INT130057 Positive_regulation of CAV1 12 0.65 8.96 0.77
95 INT136753 Regulation of Gene_expression of SCARB1 2 0.60 7.79 0.77
96 INT197495 Negative_regulation of Localization of Apoe 6 0.43 2.19 0.73
97 INT112088 Regulation of Cav1 2 0.44 0.51 0.73
98 INT44612 Positive_regulation of APOE 16 0.67 5.73 0.72
99 INT136751 Negative_regulation of SCARB1 6 0.43 2.65 0.7
100 INT270428 Negative_regulation of Binding of APOE 2 0.41 1.16 0.7
101 INT113335 Regulation of Transcription of Apoe 1 0.27 0.51 0.7
102 INT153667 Localization of CAV1 15 0.76 11.92 0.68
103 INT164627 Positive_regulation of Gene_expression of ABCA1 9 0.61 3.95 0.67
104 INT25374 Negative_regulation of Negative_regulation of Apoa2 1 0.30 0.24 0.67
105 INT175580 Localization of APOE 10 0.76 18.84 0.65
106 INT136755 Negative_regulation of Gene_expression of SCARB1 2 0.57 6.61 0.63
107 INT97708 Regulation of Localization of Apoe 1 0.61 2.06 0.62
108 INT212959 Binding of Scarb1 12 0.35 7.7 0.61
109 INT86700 Regulation of Cav1 7 0.54 0.92 0.61
110 INT181888 Regulation of Apoa1 5 0.26 5.07 0.6
111 INT213118 Negative_regulation of Gene_expression of Apoa1 2 0.42 2.86 0.6
112 INT131001 Regulation of CAV1 6 0.44 3.77 0.59
113 INT141863 Negative_regulation of Gene_expression of Cav1 4 0.49 1.77 0.58
114 INT302813 Positive_regulation of Positive_regulation of SOAT1 3 0.22 4.2 0.58
115 INT113334 Positive_regulation of Positive_regulation of Apoe 1 0.50 0.6 0.56
116 INT277710 Regulation of Localization of ABCA1 1 0.04 1.73 0.56
117 INT264133 Protein_catabolism of SOAT1 1 0.05 0.38 0.55
118 INT10983 Binding of Apoa2 7 0.45 4.21 0.52
119 INT20239 Regulation of APOA1 10 0.60 10.98 0.51
120 INT197322 Protein_catabolism of Apoe 6 0.71 3.52 0.51
121 INT239289 Gene_expression of Abcg1 3 0.31 2.27 0.5
122 INT217370 Phosphorylation of Apoe 2 0.63 1.8 0.49
123 INT170346 Gene_expression of Npc1 18 0.78 7.69 0.48
124 INT136757 Regulation of SCARB1 4 0.27 1.96 0.48
125 INT43397 Positive_regulation of Localization of Apoa2 1 0.09 0 0.48
126 INT86702 Localization of Cav1 8 0.69 0.76 0.47
127 INT3477 Regulation of Npc1 6 0.45 1.87 0.47
128 INT153672 Negative_regulation of Negative_regulation of CAV1 1 0.25 0.2 0.46
129 INT98945 Negative_regulation of Positive_regulation of SOAT1 1 0.41 0.65 0.46
130 INT96816 Regulation of APOE 8 0.45 6.62 0.44
131 INT220504 Positive_regulation of Gene_expression of Cav1 11 0.39 6.26 0.43
132 INT167468 Regulation of Gene_expression of ABCA1 5 0.52 0.08 0.43
133 INT190882 Regulation of Gene_expression of Apoa1 4 0.23 3.67 0.43
134 INT166240 Regulation of Gene_expression of Cav1 3 0.51 1.03 0.43
135 INT156997 Localization of NPC1 19 0.64 30 0.42
136 INT249596 Positive_regulation of Gene_expression of SOAT1 2 0.09 1.1 0.42
137 INT174753 Gene_expression of Apoa2 15 0.75 13.82 0.41
138 INT335112 Regulation of Localization of APOC3 1 0.13 0.73 0.4
139 INT97712 Negative_regulation of Transcription of Apoe 1 0.43 1.05 0.4
140 INT335117 Localization of APOC3 1 0.40 0.73 0.4
141 INT190691 Negative_regulation of APOA1 12 0.42 15.9 0.39
142 INT209180 Transcription of ABCA1 4 0.47 1.09 0.39
143 INT291958 Negative_regulation of Phosphorylation of SOAT1 2 0.05 0.58 0.39
144 INT345322 Regulation of Transcription of ABCA1 1 0.01 0 0.39
145 INT181883 Negative_regulation of Negative_regulation of Apoa1 1 0.40 1.24 0.39
146 INT220506 Binding of Cav1 13 0.45 5.46 0.38
147 INT344684 Positive_regulation of Gene_expression of Abcg1 1 0.10 0.95 0.38
148 INT167122 Protein_catabolism of ABCA1 3 0.02 0.27 0.37
149 INT135953 Negative_regulation of Positive_regulation of Cav1 2 0.37 1.09 0.37
150 INT72673 Transcription of APOA1 2 0.52 1.2 0.36
151 INT163277 Negative_regulation of Gene_expression of CAV1 17 0.56 10.77 0.35
152 INT97859 Localization of Npc1 12 0.75 6.66 0.35
153 INT317741 Positive_regulation of Transcription of SOAT1 2 0.49 0.62 0.35
154 INT4133 Binding of Npc1 14 0.47 8.24 0.33
155 INT131542 Negative_regulation of Gene_expression of APOE 6 0.40 3.92 0.33
156 INT32509 Positive_regulation of Npc1 6 0.50 2.24 0.33
157 INT261209 Localization of Apoa1 4 0.73 2.61 0.33
158 INT16855 Binding of Scarb1 1 0.21 0 0.33
159 INT16856 Positive_regulation of Binding of Scarb1 1 0.27 0 0.33
160 INT239295 Positive_regulation of Abca1 3 0.30 2.18 0.32
161 INT47453 Positive_regulation of Positive_regulation of Apoa2 3 0.31 1.17 0.32
162 INT307779 Positive_regulation of Localization of Apoa1 1 0.49 0.88 0.31
163 INT189968 Binding of APOA1 12 0.47 10.1 0.3
164 INT190878 Positive_regulation of Gene_expression of Apoc3 3 0.29 2.76 0.3
165 INT311128 Positive_regulation of Regulation of Apoe 1 0.30 0.3 0.3
166 INT43396 Regulation of Localization of Apoa2 1 0.09 0 0.3
167 INT175687 Transcription of Apoe 4 0.72 2.12 0.29
168 INT96815 Regulation of Gene_expression of APOE 2 0.62 1.1 0.29
169 INT141867 Positive_regulation of Transcription of Cav1 2 0.52 0.46 0.29
170 INT141868 Transcription of Cav1 2 0.54 1.48 0.29
171 INT141861 Negative_regulation of Binding of Cav1 1 0.44 0.4 0.29
172 INT344673 Positive_regulation of Binding of Scarb1 1 0.16 0.82 0.28
173 INT297322 Binding of Apoa2 3 0.36 1.7 0.27
174 INT97711 Positive_regulation of Transcription of Apoe 1 0.46 1.06 0.27
175 INT201565 Positive_regulation of Gene_expression of NPC1 5 0.43 5.94 0.26
176 INT239279 Regulation of Gene_expression of Abca1 2 0.44 2.42 0.26
177 INT254756 Regulation of Positive_regulation of Apoe 1 0.20 0.22 0.26
178 INT344685 Positive_regulation of Binding of Abca1 1 0.12 0.76 0.26
179 INT284385 Positive_regulation of Localization of ABCA1 2 0.02 0.22 0.25
180 INT67227 Positive_regulation of Binding of Apoa2 2 0.26 1.31 0.25
181 INT309880 Positive_regulation of Localization of NPC1 1 0.04 1.06 0.25
182 INT2450 Negative_regulation of Positive_regulation of Apoa2 1 0.21 0 0.24
183 INT32508 Positive_regulation of Positive_regulation of Npc1 2 0.47 0.67 0.23
184 INT135956 Phosphorylation of Cav1 5 0.64 2.24 0.22
185 INT135954 Positive_regulation of Phosphorylation of Cav1 2 0.40 0.64 0.22
186 INT307183 Positive_regulation of Gene_expression of Scarb1 1 0.07 0.93 0.22
187 INT2449 Negative_regulation of Localization of Apoa2 1 0.19 0 0.22
188 INT141860 Regulation of Localization of Cav1 1 0.20 0.2 0.22
189 INT323964 Negative_regulation of Binding of Apoe 1 0.39 0.35 0.22
190 INT323965 Protein_catabolism of Apoa2 1 0.01 0.34 0.22
191 INT198892 Regulation of Binding of Apoe 6 0.45 2.94 0.21
192 INT186199 Binding of SCARB1 3 0.37 5.25 0.21
193 INT323896 Regulation of Phosphorylation of SOAT1 2 0.14 1.25 0.21
194 INT239287 Transcription of Abca1 1 0.32 1.87 0.21
195 INT176221 Positive_regulation of Abcg5 1 0.69 0.24 0.21
196 INT171597 Gene_expression of APOC3 9 0.77 3.18 0.2
197 INT180454 Negative_regulation of Apoa2 6 0.42 7.42 0.2
198 INT193810 Phosphorylation of APOE 2 0.27 1.13 0.2
199 INT190874 Negative_regulation of Gene_expression of Apoa1 1 0.15 0.9 0.2
200 INT335113 Negative_regulation of Gene_expression of APOC3 1 0.24 0.34 0.2
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