GO:0033554

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Name cellular response to stress
Categary Process
Go Slim No
Go Link GO:0033554
Unique Molecular Interactions 325
Total Molecular Interactions 430
Total Single Events 4931
Pain Genes Associated 19

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cellular response to stress. They are ordered first by their pain relevance and then by number of times they were reported for cellular response to stress. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT221180 Binding of OPRM1 and Flna 1 0.09 0.22 12.65
2 INT134284 Binding of OPRM1 and PLD2 1 0.52 0 3.72
3 INT322411 Hist1h1t Positive_regulation of Positive_regulation of OPRM1 1 0.00 1.25 3.63
4 INT18026 Binding of Oprd1 and Oprm1 4 0.40 0.83 3.53
5 INT195931 Binding of OPRM1 and Trpv1 1 0.07 0.87 3.43
6 INT318474 Positive_regulation of OPRM1 Positive_regulation of Localization of CA2 1 0.17 0.55 2.7
7 INT96461 Pnoc Positive_regulation of Oprm1 1 0.09 0.73 2.34
8 INT88730 Binding of OPRM1 and Mop3 1 0.00 0 2.34
9 INT322410 Hist1h1t Positive_regulation of Phosphorylation of OPRM1 1 0.00 0.08 2.31
10 INT134583 Arrb2 Regulation of Oprm1 1 0.41 1.23 2.15
11 INT318473 Positive_regulation of OPRM1 Positive_regulation of CA2 1 0.17 0.46 2.13
12 INT51198 Positive_regulation of Binding of OPRM1 and PDYN 2 0.18 0.3 2.08
13 INT51199 Binding of OPRM1 and PDYN 2 0.13 0.3 2.08
14 INT64750 Binding of Oprm1 and Pck1 2 0.41 0.51 2.07
15 INT107738 Binding of Pld2 and Oprm1 1 0.23 0 1.93
16 INT113572 Binding of DMRT1 and OPRM1 1 0.01 0 1.9
17 INT29996 Binding of Oprm1 and Penk 2 0.36 0.4 1.85
18 INT167319 Binding of OPRM1 and PCSK2 1 0.22 0.63 1.77
19 INT167320 Binding of CPE and OPRM1 1 0.14 0.63 1.77
20 INT167321 Binding of ENG and OPRM1 1 0.27 0.63 1.76
21 INT157524 Binding of GRM5 and OPRM1 1 0.36 0 1.74
22 INT96296 Oprm1 Negative_regulation of Npr1 2 0.05 0.32 1.65
23 INT134742 Binding of OPRM1 and SV2A 1 0.33 0.18 1.64
24 INT135516 PRKCA Negative_regulation of Phosphorylation of OPRM1 1 0.12 0 1.62
25 INT109525 Binding of DMRT1 and Oprm1 1 0.08 0 1.62
26 INT195930 OPRM1 Regulation of Prkaca 1 0.01 0 1.59
27 INT221182 Negative_regulation of Binding of OPRM1 and Flna 1 0.07 0 1.57
28 INT116093 OPRM1 Positive_regulation of Positive_regulation of NFKB1 1 0.36 0.08 1.56
29 INT72666 Binding of ODT and Oprm1 1 0.03 0.53 1.5
30 INT161870 OPRM1 Positive_regulation of Prkcg 1 0.01 0.12 1.47
31 INT141673 Oprm1 Positive_regulation of Negative_regulation of Ltp 1 0.13 0 1.46
32 INT141676 OPRM1 Positive_regulation of Ltp 1 0.04 0 1.46
33 INT141674 Oprm1 Positive_regulation of Ltp 1 0.13 0 1.46
34 INT141675 OPRM1 Positive_regulation of Negative_regulation of Ltp 1 0.04 0 1.46
35 INT131039 Binding of Oprm1 and Prf1 1 0.17 0 1.45
36 INT131041 Negative_regulation of Binding of Oprm1 and Prf1 1 0.21 0 1.45
37 INT131040 Binding of Oprm1 and S100a9 1 0.24 0 1.45
38 INT161858 OPRM1 Positive_regulation of GRIN1 1 0.50 0.12 1.45
39 INT128915 PENK Regulation of Gene_expression of OPRM1 1 0.22 0.07 1.43
40 INT96796 ITIH4 Regulation of Gene_expression of OPRM1 2 0.20 0.89 1.41
41 INT128914 COMT Regulation of OPRM1 1 0.39 0.07 1.39
42 INT162105 Nr4a3 Regulation of ACPT-I 1 0.10 0.26 1.38
43 INT51203 Binding of OPRK1 and OPRM1 2 0.29 0.3 1.36
44 INT160590 CSF2 Positive_regulation of Gene_expression of OPRM1 1 0.16 0.54 1.35
45 INT139987 Oprm1 Positive_regulation of Localization of Oprl1 1 0.16 0.17 1.35
46 INT160586 IL6 Positive_regulation of Gene_expression of OPRM1 1 0.14 0.54 1.35
47 INT160588 TNF Positive_regulation of Gene_expression of OPRM1 1 0.20 0.54 1.35
48 INT160587 IFNG Positive_regulation of Gene_expression of OPRM1 1 0.18 0.54 1.35
49 INT160585 IL18 Positive_regulation of Gene_expression of OPRM1 1 0.09 0.54 1.35
50 INT160589 IL4 Positive_regulation of Gene_expression of OPRM1 1 0.13 0.54 1.35
51 INT51200 Binding of OPRM1 and PENK 2 0.17 0.23 1.31
52 INT128310 Oprm1 Positive_regulation of Oprm1 1 0.00 0.1 1.29
53 INT89943 Binding of Oprm1 and Il2 1 0.03 0.53 1.28
54 INT195929 Binding of OPRM1 and Prkaca 1 0.02 0.33 1.27
55 INT64749 Negative_regulation of Binding of Oprm1 and Pck1 1 0.47 0.21 1.27
56 INT110542 SIGMAR1 Regulation of OPRM1 1 0.04 0.33 1.25
57 INT110543 SIGMAR1 Regulation of Gene_expression of OPRM1 1 0.04 0.33 1.25
58 INT342165 Binding of Aqp1 and Nav1 1 0.25 0.57 1.25
59 INT126801 Regulation of Binding of Oprm1 and Penk 1 0.34 0.4 1.25
60 INT167278 Binding of OPRM1 and REST 1 0.08 0.94 1.24
61 INT76165 IGKV2-30 Positive_regulation of Phosphorylation of Oprm1 1 0.00 0.08 1.22
62 INT76163 Prkaca Positive_regulation of Phosphorylation of Oprm1 1 0.02 0.08 1.22
63 INT113242 TNF Regulation of Transcription of OPRM1 2 0.45 1.53 1.19
64 INT133496 Binding of Oprm1 and Cckbr 1 0.15 0 1.19
65 INT49955 OPRM1 Positive_regulation of ADCY1 1 0.21 0.31 1.19
66 INT49956 OPRM1 Positive_regulation of SGCG 1 0.53 0.3 1.18
67 INT137144 ITIH4 Regulation of OPRM1 1 0.20 1.13 1.16
68 INT125696 Binding of OPRM1 and SNRNP70 1 0.06 0.99 1.15
69 INT221183 Binding of OPRM1 and Mors1 1 0.00 0 1.12
70 INT113540 Binding of OPRM1 and Tac1 1 0.04 0.1 1.1
71 INT127133 Positive_regulation of OPRM1 Positive_regulation of Protein_catabolism of SUCLG2 1 0.20 0.2 1.1
72 INT90145 Binding of OPRL1 and OPRM1 2 0.27 0.31 1.08
73 INT77982 Binding of YY1 and Oprm1 2 0.17 0.17 1.06
74 INT73311 Binding of Oprm1 and Pdpn 1 0.08 0.71 1.06
75 INT97013 Negative_regulation of Binding of CALM3 and OPRM1 1 0.40 0 1.05
76 INT97011 Binding of CALM3 and OPRM1 1 0.35 0 1.05
77 INT133075 TFAM Positive_regulation of Transcription of OPRM1 1 0.03 0 1.04
78 INT133072 GATA3 Positive_regulation of Transcription of OPRM1 1 0.35 0 1.04
79 INT51204 Positive_regulation of Binding of OPRK1 and OPRM1 1 0.38 0.3 1.03
80 INT70105 SCD Positive_regulation of Oprm1 1 0.01 0 1
81 INT91813 Binding of FAS and FASLG 4 0.23 9.89 0.99
82 INT147506 Binding of Ncam1 and Gtf3a 1 0.03 0.88 0.99
83 INT1415 Binding of OPRM1 and POMC 3 0.16 0.3 0.98
84 INT94989 Arrb2 Regulation of Regulation of Oprm1 1 0.24 0 0.98
85 INT147504 Binding of Ncam1 and Gdnf 1 0.31 0.87 0.98
86 INT51201 Negative_regulation of Binding of OPRM1 and PENK 1 0.20 0.23 0.98
87 INT57555 Binding of Oprm1 and Oprl1 2 0.06 0.05 0.97
88 INT157522 GRM5 Regulation of Gene_expression of OPRM1 1 0.28 0 0.97
89 INT40287 OPRM1 Positive_regulation of Negative_regulation of Prl 1 0.00 0.93 0.96
90 INT83415 Binding of Oprm1 and Ntrk1 1 0.01 0 0.96
91 INT133076 STAT6 Positive_regulation of OPRM1 1 0.38 0 0.95
92 INT152388 Binding of NFKB1 and OPRM1 1 0.04 0.14 0.94
93 INT152390 Negative_regulation of Binding of JUN and OPRM1 1 0.13 0.14 0.94
94 INT152387 Binding of JUN and OPRM1 1 0.15 0.14 0.94
95 INT152389 Negative_regulation of Binding of NFKB1 and OPRM1 1 0.05 0.14 0.94
96 INT128860 NR1H4 Negative_regulation of Gene_expression of OPRM1 1 0.15 0.31 0.92
97 INT79123 Binding of Pnoc and Oprm1 3 0.14 0 0.91
98 INT89314 Binding of CRYGS and OPRM1 1 0.07 0.08 0.91
99 INT113946 Binding of FLNA and OPRM1 1 0.10 0.37 0.9
100 INT220744 EGF Positive_regulation of Gene_expression of KRT20 1 0.01 1.26 0.9
101 INT128859 Positive_regulation of RXRA Regulation of Gene_expression of OPRM1 1 0.05 0.26 0.9
102 INT61046 Oprm1 Positive_regulation of Gh1 1 0.21 0 0.89
103 INT83417 Binding of OPRL1 and Oprm1 1 0.01 0 0.89
104 INT97184 Oprm1 Regulation of Gene_expression of Pomc 1 0.31 0 0.89
105 INT61047 Oprm1 Positive_regulation of Localization of Gh1 1 0.29 0 0.89
106 INT61048 Oprm1 Positive_regulation of Localization of Prl 1 0.16 0 0.88
107 INT61045 Oprm1 Positive_regulation of Prl 1 0.16 0 0.88
108 INT112153 Regulation of Binding of Oprm1 and Rtcd1 1 0.00 0.09 0.87
109 INT63859 Oprm1 Negative_regulation of Oprm1 1 0.10 0.08 0.86
110 INT63858 Oprm1 Negative_regulation of Penk 1 0.05 0.08 0.86
111 INT130769 FASLG Negative_regulation of Binding of FAS 1 0.10 0.66 0.86
112 INT120999 Binding of Oprm1 and Ifng 1 0.22 0.57 0.84
113 INT97012 Binding of CALM1 and OPRM1 1 0.18 0 0.82
114 INT77393 Binding of ARRB1 and OPRM1 1 0.15 0 0.82
115 INT89529 OPRM1 Regulation of CALM1 1 0.27 0 0.81
116 INT112154 Binding of Oprm1 and Rtcd1 1 0.00 0.09 0.81
117 INT90143 Negative_regulation of Binding of OPRL1 and OPRM1 1 0.31 0.07 0.8
118 INT151807 Binding of NFATC1 and OPRM1 1 0.19 0 0.79
119 INT55923 Penk Regulation of Transcription of Oprm1 1 0.26 0 0.78
120 INT55922 Penk Regulation of Oprm1 1 0.26 0 0.78
121 INT121647 Binding of Oprm1 and Atrn 1 0.01 0.12 0.77
122 INT133074 CNR2 Positive_regulation of Transcription of OPRM1 1 0.11 0 0.77
123 INT151808 NFATC1 Positive_regulation of Positive_regulation of OPRM1 1 0.20 0 0.76
124 INT96795 ITIH4 Positive_regulation of Gene_expression of OPRM1 1 0.49 0.17 0.76
125 INT128861 LBR Positive_regulation of Positive_regulation of OPRM1 1 0.19 0.36 0.75
126 INT124404 Binding of POMC and Oprm1 1 0.00 0.25 0.75
127 INT151810 JUND Positive_regulation of Positive_regulation of OPRM1 1 0.26 0 0.74
128 INT151809 JUN Positive_regulation of Positive_regulation of OPRM1 1 0.32 0 0.74
129 INT133070 Positive_regulation of CNR2 Positive_regulation of Transcription of OPRM1 1 0.11 0 0.74
130 INT151806 TRAF3IP2 Positive_regulation of Positive_regulation of OPRM1 1 0.06 0 0.74
131 INT157541 Binding of YY1 and Regulation of Gene_expression of OPRM1 1 0.31 1.21 0.72
132 INT137139 ITIH4 Positive_regulation of OPRM1 1 0.37 0.67 0.72
133 INT157539 Binding of SP1 and Regulation of Gene_expression of OPRM1 1 0.36 1.2 0.72
134 INT162162 ARF6 Regulation of OPRM1 1 0.19 0 0.71
135 INT82759 Binding of IGHG3 and OPRM1 2 0.06 0 0.7
136 INT107741 Binding of OPRM1 and Pld2 1 0.01 0 0.69
137 INT71595 Camk2a Regulation of Negative_regulation of Oprm1 1 0.04 0 0.69
138 INT130717 Binding of OPRM1 and Positive_regulation of Localization of CCL2 1 0.00 0.72 0.68
139 INT86638 POMC Negative_regulation of Gene_expression of OPRM1 1 0.34 0.33 0.68
140 INT30503 OPRM1 Regulation of Localization of Prl 1 0.00 0 0.67
141 INT169215 Binding of OPRM1 and CARTPT 1 0.00 0.22 0.67
142 INT169219 Binding of OPRM1 and Coc 1 0.01 0.22 0.67
143 INT137140 HIVEP1 Regulation of Gene_expression of OPRM1 1 0.25 0.69 0.66
144 INT121812 IL6 Regulation of OPRM1 1 0.22 0.27 0.65
145 INT101716 JUND Regulation of Regulation of OPRM1 1 0.09 0.06 0.65
146 INT322385 PPBP Negative_regulation of Positive_regulation of OPRM1 1 0.00 0 0.64
147 INT137145 HIVEP1 Regulation of OPRM1 1 0.10 0.7 0.64
148 INT122823 ERCC2 Regulation of Negative_regulation of OPRM1 1 0.23 0.17 0.63
149 INT160880 Pld2 Positive_regulation of Oprm1 1 0.07 0.08 0.63
150 INT160882 Pld2 Positive_regulation of Gene_expression of Oprm1 1 0.06 0.08 0.63
151 INT30502 Negative_regulation of OPRM1 Negative_regulation of Gh 1 0.00 0 0.63
152 INT282286 Akt1 Positive_regulation of Pak1 1 0.15 0.24 0.61
153 INT101718 PLAT Positive_regulation of Transcription of OPRM1 1 0.22 0.06 0.61
154 INT113962 OPRM1 Regulation of CREB1 1 0.39 0.31 0.6
155 INT126951 PNOC Positive_regulation of OPRM1 1 0.21 0.06 0.6
156 INT6723 Negative_regulation of Pomc Positive_regulation of Positive_regulation of Oprm1 1 0.20 0.55 0.6
157 INT64776 Binding of Oprm1 and Kcnj3 1 0.38 0 0.6
158 INT117707 Oprm1 Positive_regulation of PIK3CG 1 0.00 0.08 0.6
159 INT137138 ITIH4 Positive_regulation of Positive_regulation of OPRM1 1 0.42 0.55 0.59
160 INT148257 NR4A2 Regulation of Gene_expression of SLC6A3 1 0.60 0.4 0.59
161 INT59201 ecs Positive_regulation of Ncam1 1 0.01 0.98 0.59
162 INT123009 Oprm1 Positive_regulation of Localization of OR6K2 1 0.00 0 0.59
163 INT50434 Binding of Oprm1 and Mop3 1 0.00 0 0.58
164 INT121813 IL6 Positive_regulation of OPRM1 1 0.28 0.28 0.58
165 INT159125 Binding of OPRM1 and SUGT1 1 0.03 0.31 0.57
166 INT263975 NR4A3 Negative_regulation of Positive_regulation of TBK1 1 0.02 1.2 0.57
167 INT210830 OPRM1 Negative_regulation of ADCY1 1 0.00 0.06 0.55
168 INT99486 OPRM1 Positive_regulation of MAPK3 1 0.22 0 0.55
169 INT168128 Oprm1 Regulation of Mir190 1 0.11 0 0.54
170 INT88024 Ifng Positive_regulation of Gene_expression of Faslg 2 0.50 1.19 0.53
171 INT137143 HIVEP1 Positive_regulation of OPRM1 1 0.15 0.43 0.52
172 INT113241 TRAF3IP2 Regulation of Transcription of OPRM1 1 0.05 0.82 0.52
173 INT126654 Oprd1 Regulation of Oprm1 1 0.03 0.13 0.52
174 INT113243 TNF Positive_regulation of Transcription of OPRM1 1 0.23 0.84 0.51
175 INT318472 CA2 Regulation of OPRM1 1 0.17 0 0.51
176 INT144456 Binding of GPM6A and OPRM1 1 0.07 0 0.5
177 INT115800 Positive_regulation of HRASLS Positive_regulation of Positive_regulation of OPRM1 1 0.11 0 0.49
178 INT339275 Il6 Regulation of KRT20 1 0.00 3.11 0.49
179 INT31818 Negative_regulation of Binding of Sst and Oprm1 1 0.26 0.3 0.48
180 INT31817 Positive_regulation of Binding of Sst and Oprm1 1 0.30 0.3 0.48
181 INT160881 Positive_regulation of Oprm1 Positive_regulation of Positive_regulation of Pld2 1 0.05 0.08 0.48
182 INT150536 OPRM1 Positive_regulation of Positive_regulation of IL6 1 0.04 0.38 0.48
183 INT31816 Binding of Sst and Oprm1 1 0.22 0.3 0.48
184 INT150537 OPRM1 Positive_regulation of Negative_regulation of IL6 1 0.04 0.38 0.48
185 INT150539 OPRM1 Positive_regulation of IL6 1 0.04 0.38 0.48
186 INT83690 Binding of Oprm1 and Ptprg 1 0.00 0.08 0.48
187 INT150534 OPRM1 Positive_regulation of TNF 1 0.03 0.38 0.48
188 INT150535 OPRM1 Positive_regulation of Positive_regulation of TNF 1 0.08 0.38 0.48
189 INT26338 Binding of OPRM1 and Prl 1 0.02 0.37 0.47
190 INT89647 OPRM1 Regulation of ADCY1 1 0.09 0.09 0.47
191 INT64217 Oprm1 Positive_regulation of Oprd1 1 0.24 0 0.46
192 INT73055 Binding of Oprm1 and Ncr1 1 0.07 0.32 0.45
193 INT46008 OPRM1 Regulation of Localization of PRL 1 0.14 0 0.44
194 INT254347 FASLG Negative_regulation of Gene_expression of CHI3L1 1 0.13 0.92 0.42
195 INT254350 FASLG Negative_regulation of Gene_expression of VEGFA 1 0.06 0.92 0.42
196 INT139487 Oprm1 Positive_regulation of Th 1 0.26 0.1 0.42
197 INT33006 Oprm1 Regulation of Localization of LH 1 0.03 0 0.42
198 INT139488 Oprm1 Positive_regulation of Cnr1 1 0.17 0.1 0.42
199 INT113537 Binding of OPRM1 and TACR1 1 0.01 0.1 0.42
200 INT139489 Oprm1 Positive_regulation of Penk 1 0.23 0.1 0.42

Single Events

The table below shows the top 100 pain related interactions that have been reported for cellular response to stress. They are ordered first by their pain relevance and then by number of times they were reported in cellular response to stress. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT11624 Gene_expression of OPRM1 445 0.78 72.36 294.36
2 INT6293 Gene_expression of Oprm1 312 0.78 48.73 215.61
3 INT5930 Positive_regulation of Oprm1 221 0.70 31.19 172.93
4 INT4768 Positive_regulation of OPRM1 212 0.70 31.09 164.28
5 INT6042 Binding of Oprm1 248 0.48 31.77 154.34
6 INT4658 Binding of OPRM1 188 0.48 25.96 136.24
7 INT5931 Regulation of Oprm1 149 0.62 18.15 125.93
8 INT5906 Negative_regulation of Oprm1 125 0.59 19.58 101.57
9 INT1639 Negative_regulation of OPRM1 107 0.59 13.86 90.37
10 INT7528 Regulation of OPRM1 100 0.62 20.63 80.57
11 INT49747 Transcription of Oprm1 68 0.72 9.01 53.78
12 INT69484 Positive_regulation of Gene_expression of OPRM1 75 0.70 12.86 52.27
13 INT1564 Localization of OPRM1 41 0.80 8.03 44.67
14 INT14137 Localization of Oprm1 56 0.81 2.88 36.09
15 INT77407 Regulation of Gene_expression of OPRM1 51 0.62 12.58 35.75
16 INT48907 Positive_regulation of Gene_expression of Oprm1 53 0.69 8.55 33.52
17 INT10248 Gene_expression of KRT20 436 0.78 231.96 32.88
18 INT69483 Transcription of OPRM1 45 0.72 7.31 30.22
19 INT49431 Phosphorylation of OPRM1 31 0.82 2.2 29.09
20 INT104567 Gene_expression of Aqp1 47 0.78 44.84 28.68
21 INT6294 Regulation of Gene_expression of Oprm1 28 0.62 6.77 22.79
22 INT21105 Phosphorylation of Oprm1 32 0.82 0.83 19.29
23 INT18672 Gene_expression of Ncam1 54 0.78 36.64 18.79
24 INT58495 Positive_regulation of Positive_regulation of Oprm1 22 0.49 2.44 17.66
25 INT6043 Negative_regulation of Binding of Oprm1 24 0.57 2.67 16.78
26 INT32753 Positive_regulation of Positive_regulation of OPRM1 19 0.62 3.3 16.73
27 INT76863 Negative_regulation of Gene_expression of OPRM1 21 0.57 6.56 13.69
28 INT80883 Positive_regulation of Phosphorylation of OPRM1 13 0.69 1.03 13.65
29 INT68814 Positive_regulation of Transcription of Oprm1 16 0.60 2.72 13.57
30 INT6044 Regulation of Binding of Oprm1 16 0.61 3.01 11.11
31 INT59766 Positive_regulation of Negative_regulation of Oprm1 9 0.50 1.31 11.08
32 INT71592 Negative_regulation of Gene_expression of Oprm1 11 0.58 4.03 10.37
33 INT49483 Regulation of Positive_regulation of Oprm1 8 0.61 2.34 9.4
34 INT86851 Gene_expression of Faslg 45 0.75 24.42 9.21
35 INT33209 Positive_regulation of Binding of OPRM1 8 0.68 0.63 8.95
36 INT76162 Positive_regulation of Phosphorylation of Oprm1 11 0.69 0.64 8.72
37 INT18021 Positive_regulation of Binding of Oprm1 16 0.70 2.53 8.38
38 INT31060 Negative_regulation of Binding of OPRM1 12 0.37 2.65 7.75
39 INT101721 Positive_regulation of Transcription of OPRM1 8 0.48 1.22 7.74
40 INT95133 Gene_expression of FASLG 38 0.75 44.09 7.51
41 INT121815 Regulation of Positive_regulation of OPRM1 7 0.62 0.75 7.36
42 INT16628 Negative_regulation of Positive_regulation of Oprm1 9 0.43 0.89 6.92
43 INT5932 Regulation of Regulation of Oprm1 7 0.61 0.44 6.47
44 INT42832 Negative_regulation of Positive_regulation of OPRM1 6 0.36 0.96 6.35
45 INT38672 Binding of KRT20 69 0.39 48.01 6.31
46 INT97600 Regulation of Transcription of OPRM1 8 0.52 1.14 6.21
47 INT53135 Positive_regulation of Localization of Oprm1 2 0.50 0 6.12
48 INT27118 Regulation of Binding of OPRM1 10 0.62 1.18 5.97
49 INT110545 Regulation of Regulation of OPRM1 7 0.42 1.68 5.67
50 INT38671 Positive_regulation of KRT20 62 0.53 40.17 5.6
51 INT38670 Positive_regulation of Gene_expression of KRT20 68 0.69 23.25 5.55
52 INT32979 Positive_regulation of Localization of OPRM1 5 0.50 0 5.54
53 INT156134 Regulation of Gene_expression of Aqp1 5 0.59 7.2 5.3
54 INT88019 Positive_regulation of Gene_expression of Faslg 16 0.67 11.31 5.05
55 INT42833 Positive_regulation of Negative_regulation of OPRM1 6 0.48 0.12 4.95
56 INT85328 Negative_regulation of Aqp1 5 0.54 6.02 4.94
57 INT25831 Gene_expression of NR4A2 20 0.74 2.73 4.92
58 INT79902 Gene_expression of AQP1 33 0.78 24.72 4.55
59 INT137691 Positive_regulation of Gene_expression of Ncam1 9 0.68 2.3 4.24
60 INT56027 Positive_regulation of Ncam1 12 0.69 4.96 4.1
61 INT85326 Positive_regulation of Aqp1 7 0.65 5.9 3.71
62 INT80882 Negative_regulation of Phosphorylation of OPRM1 4 0.45 0.21 3.68
63 INT137688 Regulation of Gene_expression of Ncam1 1 0.60 1.21 3.65
64 INT104570 Localization of Aqp1 8 0.77 5.83 3.51
65 INT86977 Positive_regulation of Nr4a3 7 0.10 0.73 3.5
66 INT5929 Positive_regulation of Regulation of Oprm1 4 0.50 0.56 3.48
67 INT13347 Regulation of Negative_regulation of OPRM1 5 0.45 0.64 3.38
68 INT95652 Gene_expression of Krt20 54 0.61 53.69 3.31
69 INT70377 Regulation of Transcription of Oprm1 3 0.47 0.93 2.78
70 INT38673 Negative_regulation of KRT20 38 0.42 22.49 2.77
71 INT86980 Transcription of Nr4a3 4 0.45 0.24 2.58
72 INT64062 Negative_regulation of Regulation of OPRM1 2 0.41 0.3 2.48
73 INT50723 Positive_regulation of Nr4a2 7 0.53 0.47 2.46
74 INT95136 Binding of FASLG 6 0.33 8.01 2.41
75 INT99607 Transcription of NR4A2 2 0.68 1.61 2.41
76 INT137960 Positive_regulation of FASLG 8 0.67 6.5 2.34
77 INT93395 Transcription of Faslg 6 0.51 5.64 2.26
78 INT137690 Negative_regulation of Gene_expression of Ncam1 3 0.50 3.37 2.18
79 INT71952 Regulation of Negative_regulation of Oprm1 3 0.43 0.09 2.18
80 INT38674 Regulation of KRT20 32 0.44 19 2.15
81 INT2611 Negative_regulation of AQP1 17 0.39 10.04 2.15
82 INT141721 Binding of Aqp1 5 0.37 1.77 2.15
83 INT161382 Localization of KRT20 25 0.61 12.97 2.13
84 INT203308 Regulation of Aqp1 4 0.48 2.59 2.13
85 INT32980 Positive_regulation of Regulation of OPRM1 2 0.45 0 1.98
86 INT111143 Regulation of Gene_expression of KRT20 22 0.26 5.65 1.93
87 INT88016 Negative_regulation of Gene_expression of Faslg 5 0.54 2.18 1.93
88 INT102147 Negative_regulation of Faslg 5 0.19 4.56 1.92
89 INT130775 Regulation of FASLG 4 0.30 5.8 1.82
90 INT142684 Protein_catabolism of OPRM1 2 0.66 0.48 1.81
91 INT56028 Regulation of Ncam1 6 0.38 3.6 1.78
92 INT81169 Localization of Nr4a2 1 0.68 0 1.71
93 INT50724 Positive_regulation of Positive_regulation of Nr4a2 2 0.49 0.17 1.58
94 INT93394 Positive_regulation of Transcription of Faslg 1 0.24 3.57 1.57
95 INT130552 Negative_regulation of Localization of Oprm1 2 0.31 0.37 1.53
96 INT137819 Binding of Faslg 3 0.09 1.78 1.51
97 INT53008 Gene_expression of Nr4a2 25 0.74 4.89 1.5
98 INT88015 Positive_regulation of Faslg 5 0.65 5.73 1.44
99 INT21106 Regulation of Phosphorylation of Oprm1 3 0.61 0 1.43
100 INT211054 Positive_regulation of AQP1 3 0.33 4.53 1.41
101 INT86979 Positive_regulation of Transcription of Nr4a3 1 0.02 0.13 1.38
102 INT327824 Positive_regulation of Gene_expression of Aqp1 4 0.67 5.4 1.37
103 INT86978 Regulation of Nr4a3 1 0.02 0.06 1.37
104 INT73553 Gene_expression of Aqp1 23 0.67 4.65 1.34
105 INT115804 Regulation of Localization of OPRM1 2 0.33 0.12 1.33
106 INT85667 Negative_regulation of Negative_regulation of Oprm1 3 0.37 0.54 1.31
107 INT137382 Negative_regulation of Gene_expression of KRT20 22 0.58 12.29 1.29
108 INT102200 Gene_expression of Nr4a2 9 0.72 3.69 1.28
109 INT67450 Negative_regulation of Localization of OPRM1 2 0.06 0.24 1.26
110 INT135551 Positive_regulation of Gene_expression of FASLG 2 0.67 6.71 1.26
111 INT14138 Regulation of Localization of Oprm1 1 0.28 0 1.23
112 INT130774 Transcription of FASLG 5 0.67 2.02 1.22
113 INT35786 Negative_regulation of Negative_regulation of OPRM1 2 0.33 0.91 1.1
114 INT124317 Regulation of Gene_expression of FASLG 2 0.23 1.54 1.1
115 INT5006 Transcription of KRT20 9 0.46 7.11 1.03
116 INT166889 Positive_regulation of Gene_expression of AQP1 10 0.70 6.43 0.99
117 INT21108 Negative_regulation of Phosphorylation of Oprm1 2 0.43 0 0.98
118 INT183362 Regulation of AQP1 3 0.23 1.49 0.92
119 INT148259 Negative_regulation of Gene_expression of NR4A2 2 0.55 0.71 0.91
120 INT168377 Negative_regulation of Binding of KRT20 3 0.35 2.14 0.89
121 INT122813 Binding of Krt20 11 0.32 13.77 0.88
122 INT130770 Positive_regulation of Transcription of FASLG 1 0.22 0.68 0.87
123 INT167424 Positive_regulation of Pak1 1 0.14 1.43 0.83
124 INT86852 Regulation of Faslg 3 0.42 1.67 0.79
125 INT55921 Negative_regulation of Transcription of Oprm1 1 0.43 0 0.76
126 INT148261 Negative_regulation of Transcription of NR4A2 1 0.41 0.31 0.72
127 INT90714 Positive_regulation of Nr4a2 1 0.67 0.97 0.71
128 INT86976 Regulation of Transcription of Nr4a3 1 0.01 0.06 0.7
129 INT78800 Negative_regulation of Ncam1 2 0.36 0.58 0.69
130 INT129375 Negative_regulation of Regulation of Oprm1 1 0.28 0.49 0.68
131 INT206139 Phosphorylation of KRT20 8 0.48 9.1 0.66
132 INT264000 Positive_regulation of Transcription of NR4A3 1 0.28 1.01 0.65
133 INT95135 Negative_regulation of Gene_expression of FASLG 4 0.20 2.99 0.64
134 INT263999 Transcription of NR4A3 1 0.40 0.98 0.63
135 INT149974 Positive_regulation of Gene_expression of NR4A2 4 0.41 0.52 0.58
136 INT349704 Gene_expression of Nr4a3 1 0.65 0.05 0.57
137 INT148260 Negative_regulation of NR4A2 2 0.36 0.68 0.56
138 INT148258 Regulation of Gene_expression of NR4A2 1 0.26 0.39 0.56
139 INT148265 Regulation of Transcription of NR4A2 1 0.58 0.39 0.56
140 INT320854 Localization of NR4A3 1 0.28 0.2 0.56
141 INT139780 Binding of AQP1 7 0.32 4.62 0.54
142 INT105782 Positive_regulation of Krt20 9 0.20 9.62 0.53
143 INT349708 Positive_regulation of Gene_expression of Nr4a3 1 0.42 0.05 0.52
144 INT95163 Binding of Ncam1 3 0.32 1.02 0.5
145 INT95161 Localization of Ncam1 5 0.80 1.01 0.45
146 INT19592 Localization of AQP1 4 0.81 1.09 0.44
147 INT327786 Negative_regulation of Gene_expression of AQP1 3 0.29 4.21 0.44
148 INT305077 Localization of CRHBP 1 0.76 0.28 0.44
149 INT323752 Negative_regulation of FASLG 2 0.18 2.36 0.43
150 INT88021 Regulation of Gene_expression of Faslg 4 0.60 2.6 0.38
151 INT95132 Negative_regulation of Binding of FASLG 1 0.18 0.63 0.38
152 INT203374 Positive_regulation of Regulation of Aqp1 2 0.36 0.91 0.37
153 INT90716 Regulation of Gene_expression of Nr4a2 2 0.43 0.41 0.32
154 INT293551 Regulation of Positive_regulation of Aqp1 1 0.13 0 0.31
155 INT18041 Protein_catabolism of Oprm1 1 0.87 0 0.31
156 INT99609 Localization of NR4A2 2 0.73 0.6 0.3
157 INT99611 Negative_regulation of Localization of NR4A2 1 0.42 0.41 0.3
158 INT247097 Binding of CRHBP 3 0.34 0.4 0.28
159 INT277711 Regulation of Localization of KRT20 1 0.37 0.87 0.28
160 INT89620 Phosphorylation of Ncam1 1 0.19 0.52 0.28
161 INT246013 Transcription of Nr4a2 4 0.46 1.29 0.27
162 INT148898 Negative_regulation of Gene_expression of Nr4a2 3 0.54 1.13 0.26
163 INT276798 Positive_regulation of NR4A2 2 0.16 0.08 0.25
164 INT95162 Negative_regulation of Localization of Ncam1 2 0.37 0.17 0.24
165 INT88018 Positive_regulation of Positive_regulation of Faslg 1 0.47 0.75 0.23
166 INT130886 Regulation of Krt20 1 0.02 0.91 0.23
167 INT214557 Regulation of Binding of KRT20 3 0.37 2.25 0.22
168 INT56026 Positive_regulation of Regulation of Ncam1 1 0.37 0.24 0.22
169 INT94547 Localization of Faslg 1 0.76 0.71 0.21
170 INT104568 Negative_regulation of Localization of Aqp1 1 0.36 2.47 0.2
171 INT215814 Negative_regulation of Gene_expression of Aqp1 2 0.31 0.25 0.17
172 INT98625 Regulation of Aqp1 1 0.27 0.1 0.17
173 INT136426 Positive_regulation of Gene_expression of NR4A3 1 0.49 0.23 0.17
174 INT136427 Gene_expression of NR4A3 1 0.75 0.23 0.17
175 INT55496 Phosphorylation of Ppp2r2b 1 0.23 0 0.16
176 INT55497 Negative_regulation of Phosphorylation of Ppp2r2b 1 0.16 0 0.16
177 INT274662 Positive_regulation of Binding of KRT20 3 0.39 4.32 0.15
178 INT55499 Localization of Ppp2r2b 1 0.26 0 0.15
179 INT55498 Negative_regulation of Ppp2r2b 1 0.16 0 0.15
180 INT245803 Protein_catabolism of Ppp2r2b 2 0.02 3.02 0.13
181 INT217718 Positive_regulation of Localization of KRT20 4 0.16 1.24 0.12
182 INT159223 Binding of NR4A2 2 0.47 0.38 0.12
183 INT197289 Transcription of Nr4a2 1 0.06 0.06 0.12
184 INT217722 Protein_catabolism of KRT20 21 0.28 1.33 0.1
185 INT215820 Negative_regulation of Aqp1 3 0.23 0.83 0.1
186 INT159343 Positive_regulation of Localization of AQP1 1 0.11 0 0.1
187 INT20955 Binding of Pak1 1 0.30 0.76 0.09
188 INT84940 Binding of Nr4a2 1 0.35 0.09 0.08
189 INT327827 Negative_regulation of Gene_expression of Aqp1 1 0.45 0.8 0.08
190 INT20954 Gene_expression of Pak1 3 0.58 1.47 0.07
191 INT262510 Regulation of Gene_expression of Aqp1 1 0.33 1.18 0.07
192 INT250476 Negative_regulation of Transcription of FASLG 1 0.22 0.76 0.06
193 INT217724 Negative_regulation of Protein_catabolism of KRT20 1 0.00 0.1 0.05
194 INT246012 Negative_regulation of Gene_expression of Nr4a2 1 0.29 0.06 0.05
195 INT300432 Negative_regulation of Protein_catabolism of Ppp2r2b 1 0.01 1.52 0.05
196 INT246014 Negative_regulation of Nr4a2 1 0.29 0 0.05
197 INT175765 Positive_regulation of NR4A3 2 0.45 0.11 0.03
198 INT246015 Localization of Nr4a2 1 0.50 0 0.03
199 INT217717 Positive_regulation of Protein_catabolism of KRT20 5 0.16 0.98 0
200 INT299486 Localization of Krt20 2 0.19 1.49 0
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