GO:0033574

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Name response to testosterone stimulus
Categary Process
Go Slim No
Go Link GO:0033574
Unique Molecular Interactions 609
Total Molecular Interactions 860
Total Single Events 9503
Pain Genes Associated 40

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for response to testosterone stimulus. They are ordered first by their pain relevance and then by number of times they were reported for response to testosterone stimulus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT140015 Avp Positive_regulation of Localization of Penk 3 0.63 3.48 6.63
2 INT128296 Negative_regulation of IL1B Positive_regulation of Insr 1 0.10 1.36 4.52
3 INT128295 IL1B Positive_regulation of Insr 1 0.11 1.36 4.5
4 INT38217 Penk Regulation of Localization of Avp 2 0.38 0.56 4.45
5 INT161109 Avp Positive_regulation of Chkb 1 0.12 0.18 4.19
6 INT15984 Binding of Avp and Oxt 11 0.32 1.33 3.64
7 INT140011 Avp Positive_regulation of Dbi 2 0.07 0.93 3.61
8 INT128293 Negative_regulation of Aldh1a1 Positive_regulation of Insr 1 0.00 0.99 3.34
9 INT128292 Nts Positive_regulation of Insr 1 0.03 0.99 3.34
10 INT128291 Vom1r68 Positive_regulation of Insr 1 0.00 0.99 3.33
11 INT128294 Aldh1a1 Positive_regulation of Insr 1 0.00 0.99 3.33
12 INT140014 Avp Negative_regulation of Chkb 1 0.04 1.58 2.86
13 INT7888 Oprl1 Regulation of Localization of Avp 4 0.49 0.25 2.63
14 INT66803 Oxt Regulation of Avp 7 0.16 0.19 2.15
15 INT140019 Avp Positive_regulation of Localization of Kitl 1 0.00 1 2.13
16 INT138960 Dbi Positive_regulation of Avp 1 0.02 1.53 2
17 INT138958 Dbi Positive_regulation of Positive_regulation of Avp 1 0.02 1.53 2
18 INT45423 Avp Positive_regulation of Localization of Prl 4 0.67 1.37 1.98
19 INT91607 Binding of EDN1 and POMC 1 0.12 0 1.9
20 INT40239 Penk Regulation of Avp 1 0.07 0 1.84
21 INT117269 Binding of Avp and Prl 1 0.25 0.47 1.8
22 INT10202 Agt Positive_regulation of Avp 3 0.70 0 1.69
23 INT291578 Negative_regulation of Pde12 Positive_regulation of Pde5a 1 0.03 1.11 1.67
24 INT140009 Avp Positive_regulation of Gene_expression of Penk 1 0.40 0.77 1.64
25 INT140023 Avp Positive_regulation of Gene_expression of Kitl 1 0.00 0.76 1.62
26 INT136034 Edn1 Regulation of Trpv1 2 0.66 0.39 1.58
27 INT94271 Pomc Regulation of Avp 1 0.20 0.67 1.57
28 INT89011 Lep Positive_regulation of Insr 1 0.19 2.41 1.57
29 INT113337 EPO Positive_regulation of JAK2 1 0.76 2.8 1.55
30 INT140013 Avp Positive_regulation of Gene_expression of Dbi 1 0.07 0.85 1.52
31 INT140016 Avp Positive_regulation of Gene_expression of Pdyn 1 0.21 0.85 1.52
32 INT140017 Avp Positive_regulation of Gene_expression of Pomc 1 0.38 0.85 1.52
33 INT140008 Avp Positive_regulation of Pomc 1 0.38 0.84 1.51
34 INT59547 Avp Positive_regulation of Crh 2 0.14 1.13 1.47
35 INT291583 GUCY2C Regulation of Pde5a 1 0.00 1.12 1.45
36 INT45307 ENG Positive_regulation of Localization of Avp 1 0.00 0 1.45
37 INT140012 Avp Negative_regulation of Dbi 1 0.06 0.8 1.44
38 INT5534 Binding of Oxt and Avp 7 0.04 0.6 1.43
39 INT142490 Avp Regulation of Oxt 1 0.09 0.74 1.4
40 INT140021 Avp Positive_regulation of Pag1 1 0.03 0.85 1.38
41 INT140018 Avp Positive_regulation of Gene_expression of Pag1 1 0.04 0.85 1.38
42 INT140020 Avp Positive_regulation of Localization of Pag1 1 0.03 0.85 1.38
43 INT150890 Binding of Esr1 and Esr2 2 0.52 2.06 1.31
44 INT95275 Binding of Edn1 and Ece1 1 0.32 2.09 1.3
45 INT95274 Regulation of Binding of Edn1 and Ece1 1 0.39 2.09 1.3
46 INT69279 Regulation of Binding of TSPO and Gabrg1 1 0.00 2.05 1.26
47 INT348380 Binding of Fdps and Lpar5 1 0.07 1.45 1.25
48 INT62596 Binding of Edn1 and Nppa 1 0.27 1.77 1.22
49 INT140010 Avp Regulation of Gene_expression of Penk 1 0.25 0.58 1.19
50 INT201067 Binding of Edn1 and Ednra 2 0.18 1.36 1.18
51 INT75126 Pnoc Regulation of Localization of Avp 2 0.26 0.24 1.18
52 INT27621 Avp Positive_regulation of Protein_catabolism of Mbis1 1 0.00 0 1.18
53 INT140022 Avp Regulation of Localization of Pag1 1 0.01 0.57 1.17
54 INT43509 Avp Positive_regulation of Localization of POMC 2 0.13 1.26 1.16
55 INT164722 Avp Regulation of NT5C 1 0.06 0.88 1.15
56 INT94490 Il6 Positive_regulation of Gene_expression of Avp 1 0.33 1.97 1.15
57 INT94502 Il1b Positive_regulation of Gene_expression of Avp 1 0.28 1.97 1.15
58 INT59606 Binding of Tspo and Penk 1 0.04 0 1.12
59 INT2457 Agt Positive_regulation of Localization of Avp 5 0.59 0.2 1.09
60 INT10238 Binding of EDN1 and Calca 1 0.00 1.07 1.06
61 INT38936 Binding of Avp and Crh 7 0.40 0.82 1.04
62 INT133650 Epo Negative_regulation of TNF 1 0.35 2.7 1.04
63 INT352456 Dusp1 Negative_regulation of Mapk14 1 0.03 1.31 1.03
64 INT85320 Binding of Avp and Vas1 1 0.00 0.87 0.98
65 INT94493 Avp Positive_regulation of Gene_expression of Ifng 1 0.05 1.73 0.97
66 INT133652 Epo Negative_regulation of Gene_expression of TNF 1 0.35 2.64 0.96
67 INT136033 Edn1 Positive_regulation of Trpv1 1 0.50 0.34 0.95
68 INT77859 EDN1 Positive_regulation of MC1R 2 0.64 0.34 0.94
69 INT43454 Pomc Regulation of Localization of Avp 2 0.24 0.89 0.94
70 INT51542 Negative_regulation of Binding of Avp and Penk 1 0.46 0.05 0.94
71 INT51541 Positive_regulation of Binding of Avp and Penk 1 0.74 0.05 0.94
72 INT51545 Binding of Avp and Penk 1 0.51 0.05 0.94
73 INT352465 Dusp1 Negative_regulation of Gene_expression of Mapk14 1 0.03 1.09 0.92
74 INT352444 Dusp1 Negative_regulation of Phosphorylation of Mapk14 1 0.03 1.09 0.91
75 INT64127 Igfbp2 Regulation of Localization of Avp 1 0.39 0.19 0.9
76 INT257304 Pde5a Positive_regulation of Oprd1 1 0.15 0.48 0.89
77 INT310348 Binding of Tspo and Gabrd 1 0.00 0.43 0.88
78 INT121467 Binding of Avp and Ptafr 1 0.11 0.98 0.88
79 INT59497 Adh1 Regulation of POMC 1 0.03 0 0.86
80 INT26529 Prl Regulation of Avp 1 0.08 0.26 0.85
81 INT291581 Pde5a Regulation of Localization of Abat 1 0.03 0 0.83
82 INT106859 EDN1 Positive_regulation of Transcription of MC1R 1 0.22 0 0.82
83 INT16436 Ubqln1 Regulation of Localization of Avp 1 0.01 0 0.81
84 INT16439 Atp6v0d2 Regulation of Localization of Avp 1 0.02 0 0.81
85 INT219911 Edn1 Regulation of Gene_expression of Trpv1 1 0.23 0.57 0.8
86 INT108811 Esr2 Positive_regulation of Binding of Oprm1 1 0.46 0.44 0.79
87 INT47143 Negative_regulation of Agt Positive_regulation of Avp 1 0.22 0 0.79
88 INT9527 Avp Positive_regulation of Localization of Pomc 7 0.58 0.29 0.77
89 INT147251 Binding of Avp and Gal 1 0.15 0.19 0.76
90 INT76499 Binding of Insr and Adora2a 1 0.08 0 0.76
91 INT12396 Binding of Avp and IGKV1-5 3 0.04 1.38 0.75
92 INT316673 Binding of CALR and LRP1 1 0.39 1.89 0.74
93 INT45305 Pomc Positive_regulation of Localization of Avp 1 0.12 0 0.73
94 INT64117 Binding of Edn1 and Ins1 1 0.06 0.85 0.71
95 INT222493 Edn1 Positive_regulation of Localization of Prl 1 0.10 0 0.71
96 INT186674 Binding of BGLAP and CYP27A1 1 0.01 1.91 0.71
97 INT257302 Cnp Regulation of Protein_catabolism of Pde5a 1 0.05 0.49 0.7
98 INT63557 Binding of Edn1 and Edn3 1 0.23 0.63 0.7
99 INT348396 Binding of LPAR5 and Fdps 1 0.07 0.81 0.69
100 INT164713 Binding of Avp and Positive_regulation of Localization of Acot1 1 0.32 0.43 0.69
101 INT164715 Avp Positive_regulation of Localization of Acot1 1 0.28 0.43 0.69
102 INT48032 Binding of Avp and Pebp1 1 0.00 0 0.68
103 INT278827 Binding of EDN1 and EDNRB 3 0.17 2.7 0.67
104 INT11611 Cck Positive_regulation of Localization of Avp 1 0.09 0 0.67
105 INT11612 Cck Positive_regulation of Avp 1 0.10 0 0.67
106 INT313702 Binding of Edn1 and Fig4 1 0.16 0 0.65
107 INT313698 Binding of Calca and Edn1 1 0.30 0 0.65
108 INT164723 Binding of Avp and NT5C 1 0.07 0.45 0.65
109 INT160119 EPO Regulation of Gene_expression of NFKB1 1 0.02 0.2 0.64
110 INT164714 Binding of Avp and Acot1 1 0.26 0.45 0.64
111 INT348381 Fdps Positive_regulation of Lpar5 1 0.07 0.75 0.64
112 INT48033 Binding of Avp and LH 1 0.08 0 0.64
113 INT348399 Fdps Positive_regulation of LPAR5 1 0.08 0.75 0.64
114 INT318981 Binding of CALR and GOPC 1 0.03 0.77 0.64
115 INT69280 Negative_regulation of Binding of TSPO and Gabrg1 1 0.00 1.03 0.63
116 INT182266 EDN1 Positive_regulation of Gene_expression of MMP13 1 0.35 2.03 0.63
117 INT219919 EDNRA Negative_regulation of Edn1 1 0.15 0.36 0.63
118 INT178097 Binding of EDN1 and EDNRA 7 0.21 5.97 0.62
119 INT69278 Binding of TSPO and Gabrg1 1 0.00 1.01 0.62
120 INT113338 Binding of EPO and KNCN 1 0.02 1.39 0.62
121 INT46493 Binding of Insr and Oxt 1 0.14 0 0.62
122 INT32747 Avp Positive_regulation of Localization of Pomc 4 0.16 1.92 0.61
123 INT27067 Crh Positive_regulation of Localization of Avp 3 0.18 0.46 0.61
124 INT37555 FDX1 Positive_regulation of Regulation of Avp 1 0.04 0 0.61
125 INT96228 COX5A Regulation of Ak1 1 0.01 0.6 0.6
126 INT291579 Pde12 Regulation of Binding of Pde5a 1 0.02 0.41 0.6
127 INT276217 Pdk1 Positive_regulation of Positive_regulation of Insr 1 0.05 0.1 0.6
128 INT178087 EDN1 Positive_regulation of MMP13 2 0.23 1.58 0.59
129 INT89010 Arc Positive_regulation of Insr 1 0.08 0.86 0.59
130 INT352463 Gse1 Regulation of Gene_expression of Dusp1 1 0.07 0 0.59
131 INT109803 Binding of Avp and Oprl1 1 0.07 0.1 0.59
132 INT109802 Binding of Esr2 and Oprl1 1 0.22 0.1 0.59
133 INT89012 DST Positive_regulation of Insr 1 0.01 0.86 0.59
134 INT130162 Pomc Positive_regulation of Gene_expression of Edn1 1 0.25 0 0.58
135 INT94506 Tnf Positive_regulation of Gene_expression of Avp 1 0.31 0.98 0.57
136 INT62597 Binding of Edn1 and Vip 1 0.23 0.79 0.54
137 INT255463 Binding of Avp and Avpr1a 1 0.06 0.67 0.54
138 INT75129 Pnoc Negative_regulation of Avp 1 0.13 0 0.54
139 INT110474 YY1 Positive_regulation of Positive_regulation of EDN1 1 0.56 0.15 0.53
140 INT130160 Pomc Regulation of Edn1 1 0.25 0 0.53
141 INT235390 HTR1A Regulation of BGLAP 1 0.03 0.23 0.51
142 INT278825 Positive_regulation of Binding of EDN1 and EDNRB 3 0.16 1.24 0.49
143 INT55553 Avp Regulation of Serpina6 1 0.02 0 0.49
144 INT94015 Binding of EDN1 and INSRR 1 0.04 0 0.49
145 INT94024 Binding of EDN1 and EDN3 1 0.27 0 0.49
146 INT47141 Creg2-ps1 Positive_regulation of Avp 1 0.01 0 0.48
147 INT47142 Negative_regulation of Creg2-ps1 Positive_regulation of Avp 1 0.01 0 0.48
148 INT66801 Oxt Regulation of Localization of Avp 1 0.08 0 0.48
149 INT341428 EPO Positive_regulation of NGF 1 0.52 0.37 0.48
150 INT341427 EPO Positive_regulation of BDNF 1 0.52 0.36 0.48
151 INT291580 Pde5a Regulation of Abat 1 0.04 0.39 0.48
152 INT61848 Npff Regulation of Localization of Avp 1 0.26 0.3 0.48
153 INT59546 Avp Positive_regulation of Localization of Crh 1 0.05 0.08 0.47
154 INT16677 Binding of Avp and Oprd1 1 0.02 0.8 0.47
155 INT341426 EPO Regulation of NGF 1 0.51 0.5 0.47
156 INT341425 EPO Regulation of BDNF 1 0.51 0.5 0.47
157 INT59548 Negative_regulation of Avp Positive_regulation of Crh 1 0.04 0.08 0.47
158 INT37599 Ace Regulation of Localization of Insr 1 0.18 0 0.46
159 INT110476 EDN1 Positive_regulation of Localization of PRKCZ 1 0.25 0.07 0.46
160 INT175788 Il2 Positive_regulation of Localization of Avp 1 0.03 0.41 0.46
161 INT27065 Kndc1 Positive_regulation of Localization of Avp 1 0.00 0 0.46
162 INT110475 EDN1 Regulation of PRKCA 1 0.05 0.07 0.45
163 INT43453 Pomc Negative_regulation of Localization of Avp 1 0.38 0.82 0.45
164 INT235389 Binding of BGLAP and HTR1A 1 0.03 0.15 0.45
165 INT219910 EDN1 Positive_regulation of Positive_regulation of EDNRA 1 0.00 0.3 0.45
166 INT36459 Binding of Agt and Positive_regulation of Localization of Avp 1 0.38 0.19 0.43
167 INT313704 Smn1 Negative_regulation of Gene_expression of Edn1 1 0.32 0 0.42
168 INT69173 Avp Positive_regulation of Oxt 1 0.18 0 0.42
169 INT261374 Nsdhl Regulation of Esr2 1 0.05 0.76 0.41
170 INT17726 Positive_regulation of Binding of AKR1A1 and Aldh2 1 0.11 0.35 0.41
171 INT36460 Binding of Agt and Avp 1 0.28 0.16 0.4
172 INT17725 Binding of AKR1A1 and Aldh2 1 0.08 0.35 0.4
173 INT230724 EDN1 Positive_regulation of EDNRA 3 0.24 4.12 0.39
174 INT40395 Ins1 Positive_regulation of Localization of Avp 1 0.16 0.09 0.38
175 INT133651 Epo Regulation of TNF 1 0.50 1.25 0.38
176 INT173704 Binding of PCOS1 and Edn1 1 0.01 0.99 0.37
177 INT316675 Binding of CALR and SFTPD 1 0.35 0.96 0.37
178 INT313701 Calca Negative_regulation of Binding of Edn1 1 0.30 0.14 0.37
179 INT52632 Binding of TSPO and CCK 1 0.15 0.53 0.37
180 INT296306 Binding of BGLAP and SPIN1 1 0.05 1.69 0.37
181 INT245328 Binding of Esr2 and Pgr 1 0.03 0.41 0.37
182 INT336573 Ptpn2 Regulation of INSR 1 0.00 1.36 0.36
183 INT277985 Epo Positive_regulation of Epc1 1 0.03 1.36 0.36
184 INT84602 Binding of Adrb1 and Avp 1 0.00 0 0.36
185 INT201068 Binding of Edn1 and Ednrb 2 0.18 1.23 0.35
186 INT305193 Binding of Epo and Cebpz 1 0.05 0.48 0.35
187 INT187064 ARSD Negative_regulation of CYP19A1 1 0.22 0.7 0.35
188 INT242403 INSR Positive_regulation of Gene_expression of Bdkrb1 1 0.45 0.88 0.35
189 INT32699 Nppa Regulation of Avp 1 0.28 0.35 0.35
190 INT251426 Gnat3 Negative_regulation of Aldh2 1 0.22 0 0.35
191 INT84600 Binding of Avp and Aqp2 1 0.17 0 0.35
192 INT161796 Binding of ECE1 and EDN1 2 0.21 2.23 0.34
193 INT37552 Crh Regulation of Avp 1 0.22 0 0.34
194 INT37551 Positive_regulation of Crh Regulation of Avp 1 0.38 0 0.34
195 INT37554 Avp Regulation of FDX1 1 0.01 0 0.34
196 INT352445 Gse1 Positive_regulation of Gene_expression of Dusp1 1 0.06 0.41 0.34
197 INT207576 RETN Positive_regulation of Gene_expression of EDN1 1 0.05 0.78 0.33
198 INT310900 Binding of DEFB1 and Kdm5d 1 0.10 1.98 0.33
199 INT133653 Epo Regulation of Transcription of TNF 1 0.22 1.09 0.33
200 INT143567 Edn1 Regulation of Ptgs2 1 0.26 0.17 0.33

Single Events

The table below shows the top 100 pain related interactions that have been reported for response to testosterone stimulus. They are ordered first by their pain relevance and then by number of times they were reported in response to testosterone stimulus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT477 Localization of Avp 813 0.81 131.58 300.4
2 INT2451 Positive_regulation of Avp 355 0.70 102.66 147.69
3 INT1273 Gene_expression of Avp 356 0.78 90.56 138.7
4 INT4207 Regulation of Avp 267 0.62 63.72 115.33
5 INT5940 Negative_regulation of Avp 236 0.59 67.86 101.2
6 INT5610 Positive_regulation of Insr 140 0.69 37.26 86.24
7 INT4358 Positive_regulation of Localization of Avp 195 0.70 30.79 77.58
8 INT7886 Regulation of Localization of Avp 146 0.62 14.53 72.99
9 INT480 Negative_regulation of Localization of Avp 151 0.59 27.64 63.72
10 INT5034 Negative_regulation of Insr 100 0.55 28.08 54.5
11 INT17915 Gene_expression of Insr 141 0.75 47.45 48.59
12 INT5781 Gene_expression of Edn1 190 0.78 99.1 46
13 INT8905 Gene_expression of EDN1 215 0.78 157.1 34.19
14 INT8691 Localization of Insr 85 0.80 9.27 30.32
15 INT894 Binding of Avp 84 0.48 29.16 29.63
16 INT5300 Regulation of Insr 54 0.60 11.33 29.26
17 INT6726 Positive_regulation of Edn1 118 0.70 65.96 24.07
18 INT71047 Gene_expression of CYP19A1 122 0.78 68.78 22.21
19 INT76336 Negative_regulation of PDE5A 192 0.59 112.02 20.09
20 INT7470 Positive_regulation of Gene_expression of Avp 37 0.70 19.55 19.96
21 INT5499 Transcription of Avp 52 0.72 7.98 19.87
22 INT8662 Positive_regulation of EDN1 144 0.70 125.34 19.59
23 INT5048 Binding of Edn1 55 0.47 18.86 19.16
24 INT14724 Negative_regulation of CYP19A1 233 0.59 96.56 18.26
25 INT109110 Positive_regulation of Pde5a 29 0.63 11.16 16.65
26 INT1261 Localization of Adh1 63 0.81 19.36 16.09
27 INT9191 Localization of EDN1 94 0.81 57.01 14.78
28 INT2843 Gene_expression of Epo 100 0.78 62.01 14.66
29 INT8904 Positive_regulation of Gene_expression of EDN1 66 0.70 65.4 14.42
30 INT5806 Regulation of Edn1 63 0.62 23.46 13.88
31 INT6365 Localization of Edn1 56 0.81 18.84 13.83
32 INT18012 Gene_expression of EPO 169 0.78 108.36 13.75
33 INT14768 Negative_regulation of Positive_regulation of Insr 16 0.56 5.51 13.59
34 INT94861 Gene_expression of Pde5a 40 0.69 14.73 13.27
35 INT21979 Negative_regulation of EDN1 52 0.58 24.65 12.55
36 INT11141 Negative_regulation of Gene_expression of Avp 23 0.59 3.85 12.19
37 INT13743 Regulation of Gene_expression of Avp 30 0.62 6.9 11.66
38 INT21632 Positive_regulation of Adh1 32 0.70 15.67 11.65
39 INT6515 Gene_expression of BGLAP 110 0.75 45.13 10.81
40 INT15262 Negative_regulation of Positive_regulation of Avp 22 0.58 3.28 10.81
41 INT94859 Negative_regulation of Pde5a 67 0.43 33.66 10.28
42 INT18088 Binding of Tspo 26 0.48 9.12 10.2
43 INT92493 Gene_expression of Fdps 19 0.75 11.28 10.08
44 INT10184 Regulation of EDN1 44 0.62 23.78 10.06
45 INT424 Positive_regulation of TSPO 34 0.61 15.04 10.02
46 INT6516 Positive_regulation of BGLAP 45 0.67 26.61 9.9
47 INT10597 Gene_expression of Cyp19a1 27 0.78 7.48 9.11
48 INT10237 Binding of EDN1 40 0.48 16 8.48
49 INT119904 Regulation of CYP19A1 25 0.62 9.36 8.34
50 INT17250 Negative_regulation of BGLAP 35 0.57 21 8.26
51 INT13739 Positive_regulation of Positive_regulation of Avp 18 0.70 4.78 8.2
52 INT39170 Gene_expression of TSPO 76 0.78 24.11 8.05
53 INT6335 Binding of TSPO 39 0.44 10.88 7.66
54 INT10899 Positive_regulation of Gene_expression of Edn1 32 0.70 24.88 7.65
55 INT30920 Positive_regulation of Gene_expression of Insr 14 0.66 2.91 7.32
56 INT106757 Gene_expression of Dusp1 9 0.66 10.45 7.26
57 INT10104 Negative_regulation of Edn1 43 0.59 15.63 7.2
58 INT3098 Positive_regulation of Epo 46 0.70 28.27 7
59 INT4438 Negative_regulation of Localization of Adh1 18 0.59 6.23 6.95
60 INT24622 Positive_regulation of Localization of Insr 15 0.69 0.32 6.85
61 INT31333 Gene_expression of Esr2 19 0.69 8.78 6.83
62 INT15872 Positive_regulation of EPO 74 0.70 45.35 6.67
63 INT66811 Positive_regulation of Transcription of Avp 11 0.70 2.1 6.46
64 INT7138 Regulation of Regulation of Avp 10 0.36 1.99 6.37
65 INT14258 Regulation of TSPO 32 0.60 10.16 6.24
66 INT3738 Regulation of Epo 25 0.61 13.73 6.18
67 INT21032 Gene_expression of Adh1 23 0.78 22.1 6.14
68 INT135760 Regulation of Gene_expression of Cyp19a1 2 0.62 1.15 5.81
69 INT32611 Phosphorylation of Insr 13 0.80 4.18 5.77
70 INT14769 Positive_regulation of Positive_regulation of Insr 10 0.43 2.66 5.55
71 INT21380 Regulation of Transcription of Avp 10 0.62 2.6 5.46
72 INT23010 Positive_regulation of CYP19A1 28 0.58 24.18 5.37
73 INT4598 Negative_regulation of Adh1 15 0.54 4.69 5.33
74 INT106756 Positive_regulation of Gene_expression of Dusp1 7 0.59 7.65 5.24
75 INT94862 Positive_regulation of Gene_expression of Pde5a 10 0.20 4.23 5.18
76 INT4864 Regulation of BGLAP 22 0.34 10.8 5.07
77 INT10115 Gene_expression of INSR 31 0.75 11.98 4.86
78 INT38087 Regulation of Adh1 15 0.61 4.56 4.83
79 INT68260 Localization of BGLAP 34 0.78 16.04 4.63
80 INT24620 Negative_regulation of Gene_expression of Insr 14 0.39 6.98 4.61
81 INT54895 Binding of Epo 24 0.48 11.38 4.48
82 INT37139 Negative_regulation of Fdps 9 0.38 4.33 4.46
83 INT7841 Gene_expression of Tspo 10 0.75 7.63 4.45
84 INT75440 Regulation of Binding of Edn1 4 0.38 1.41 4.33
85 INT205 Negative_regulation of Cbr1 10 0.58 4.23 4.29
86 INT51084 Binding of Insr 13 0.30 4.25 4.23
87 INT33229 Gene_expression of Bad 9 0.70 6.95 4.15
88 INT83035 Binding of INSR 16 0.47 9.29 4.11
89 INT6513 Positive_regulation of Gene_expression of BGLAP 24 0.67 11.69 3.96
90 INT77385 Gene_expression of Esr2 18 0.75 4.69 3.92
91 INT17716 Gene_expression of Aldh2 14 0.77 4.38 3.61
92 INT84427 Positive_regulation of Gene_expression of TSPO 15 0.64 5.05 3.58
93 INT10824 Negative_regulation of Cyp19a1 38 0.57 25.18 3.56
94 INT4261 Positive_regulation of Localization of Adh1 11 0.61 2.04 3.49
95 INT10116 Localization of INSR 11 0.57 5.43 3.48
96 INT14060 Negative_regulation of Negative_regulation of Insr 6 0.53 3.53 3.44
97 INT122997 Phosphorylation of Rps6kb1 46 0.72 9.92 3.43
98 INT95272 Regulation of Gene_expression of Edn1 19 0.53 17.85 3.42
99 INT106760 Positive_regulation of Dusp1 16 0.59 8.5 3.35
100 INT18838 Positive_regulation of Regulation of Avp 3 0.47 0.48 3.32
101 INT30131 Positive_regulation of Negative_regulation of Avp 5 0.50 1.94 3.3
102 INT53065 Negative_regulation of Gene_expression of EPO 15 0.49 16.39 3.12
103 INT25745 Regulation of Tspo 6 0.45 0.25 3.1
104 INT131472 Regulation of Pde5a 11 0.42 6.95 3.06
105 INT19553 Negative_regulation of Regulation of Avp 5 0.43 1.74 3.06
106 INT116376 Transcription of Cyp19a1 2 0.40 0.74 3.04
107 INT91341 Negative_regulation of Gene_expression of BGLAP 17 0.55 4.91 3.02
108 INT111820 Positive_regulation of Fdps 10 0.42 10.63 3.01
109 INT133809 Negative_regulation of Gene_expression of CYP19A1 9 0.43 7.67 2.99
110 INT228677 Negative_regulation of Phosphorylation of Rps6kb1 24 0.51 3.88 2.97
111 INT113277 Positive_regulation of Gene_expression of CYP19A1 13 0.69 10.23 2.97
112 INT33717 Regulation of Localization of Adh1 15 0.54 3.3 2.91
113 INT45503 Binding of EPO 42 0.48 24.85 2.88
114 INT91342 Negative_regulation of Negative_regulation of BGLAP 2 0.55 1.39 2.88
115 INT179867 Localization of Fdps 7 0.63 3.62 2.86
116 INT8112 Regulation of EPO 38 0.58 22.04 2.76
117 INT100014 Negative_regulation of Gene_expression of EDN1 17 0.42 7.85 2.71
118 INT136675 Transcription of Pde5a 6 0.63 4.74 2.71
119 INT92877 Gene_expression of PDE5A 35 0.76 17.1 2.7
120 INT94860 Negative_regulation of Gene_expression of Pde5a 2 0.33 3.2 2.64
121 INT8111 Localization of EPO 32 0.81 19.53 2.54
122 INT257298 Regulation of Positive_regulation of Pde5a 1 0.19 2.03 2.54
123 INT29983 Localization of Bad 5 0.28 4.44 2.52
124 INT23527 Negative_regulation of Localization of Insr 10 0.39 2.58 2.5
125 INT257299 Binding of Pde5a 14 0.27 4.31 2.45
126 INT3608 Regulation of Cbr1 6 0.45 2.28 2.44
127 INT54555 Negative_regulation of CALR 10 0.41 4.41 2.4
128 INT45597 Negative_regulation of Epo 22 0.59 12.47 2.35
129 INT257301 Protein_catabolism of Pde5a 5 0.30 1.97 2.26
130 INT71048 Transcription of CYP19A1 11 0.72 8.74 2.24
131 INT55853 Positive_regulation of Positive_regulation of Edn1 11 0.61 6.5 2.21
132 INT24621 Regulation of Gene_expression of Insr 9 0.42 2.68 2.18
133 INT91340 Regulation of Localization of BGLAP 5 0.58 2.82 2.14
134 INT111113 Binding of CYP19A1 15 0.36 9.17 2.12
135 INT74131 Positive_regulation of Tspo 7 0.50 0.92 2.11
136 INT342803 Positive_regulation of Transcription of Cyp19a1 1 0.30 0.33 2.08
137 INT49253 Regulation of Gene_expression of EDN1 11 0.61 3.92 2.07
138 INT31006 Regulation of Localization of Insr 7 0.50 0.2 2.05
139 INT186893 Binding of BGLAP 10 0.37 6.19 2.02
140 INT11905 Protein_catabolism of EPO 6 1.00 2.36 2
141 INT70526 Binding of CALR 11 0.35 7.09 1.97
142 INT28926 Negative_regulation of Aldh2 11 0.58 1.25 1.97
143 INT21941 Regulation of CALR 7 0.53 3.88 1.96
144 INT81347 Regulation of Cyp19a1 7 0.40 2.1 1.94
145 INT109800 Binding of Esr2 8 0.42 1.79 1.93
146 INT165648 Negative_regulation of Transcription of Pde5a 1 0.41 3.6 1.93
147 INT49259 Regulation of Localization of EDN1 8 0.61 6.29 1.92
148 INT895 Negative_regulation of Binding of Avp 7 0.55 2.45 1.9
149 INT14257 Localization of TSPO 9 0.73 1.48 1.87
150 INT15742 Negative_regulation of EPO 37 0.59 17.44 1.84
151 INT43143 Binding of Bad 8 0.21 5.12 1.81
152 INT79815 Positive_regulation of Localization of Edn1 7 0.68 2.07 1.79
153 INT8661 Positive_regulation of Positive_regulation of EDN1 10 0.66 10.9 1.76
154 INT173700 Negative_regulation of Binding of Edn1 2 0.58 0.41 1.76
155 INT19576 Negative_regulation of Tspo 3 0.42 1.02 1.75
156 INT218303 Protein_catabolism of INSR 3 0.29 0.67 1.73
157 INT106091 Negative_regulation of Transcription of Avp 4 0.59 0.23 1.72
158 INT232645 Transcription of INSR 2 0.09 1.19 1.71
159 INT153918 Binding of Esr2 3 0.33 2.56 1.7
160 INT14842 Negative_regulation of Binding of EDN1 4 0.57 0.67 1.66
161 INT93427 Negative_regulation of Bad 4 0.02 2.5 1.63
162 INT30076 Negative_regulation of Esr2 1 0.01 0 1.63
163 INT10596 Positive_regulation of Cyp19a1 10 0.42 2.08 1.62
164 INT55479 Localization of Epo 13 0.81 6.1 1.53
165 INT139263 Gene_expression of Mstn 10 0.62 6.67 1.51
166 INT181579 Phosphorylation of Edn1 1 0.71 8.59 1.51
167 INT11418 Positive_regulation of Cbr1 5 0.14 1.82 1.5
168 INT24768 Negative_regulation of Gene_expression of Edn1 10 0.43 2.85 1.48
169 INT3607 Gene_expression of Cbr1 4 0.59 1.17 1.48
170 INT27762 Positive_regulation of Gene_expression of EPO 18 0.70 17.67 1.45
171 INT18495 Regulation of Bad 6 0.19 4.79 1.45
172 INT291576 Positive_regulation of Protein_catabolism of Pde5a 1 0.12 1.15 1.43
173 INT127889 Regulation of Gene_expression of CYP19A1 11 0.62 6.7 1.41
174 INT125007 Gene_expression of DEFB1 30 0.60 4.14 1.32
175 INT154081 Negative_regulation of Localization of Bad 2 0.16 2.06 1.31
176 INT242945 Localization of PDE5A 9 0.75 4.57 1.28
177 INT167056 Gene_expression of CALR 29 0.75 20.05 1.25
178 INT60685 Positive_regulation of Gene_expression of Epo 21 0.53 15.86 1.25
179 INT10117 Positive_regulation of INSR 10 0.43 4.71 1.22
180 INT228670 Negative_regulation of Rps6kb1 12 0.38 5.27 1.21
181 INT79598 Regulation of PDE5A 16 0.60 8.68 1.17
182 INT150074 Gene_expression of WNT5A 8 0.75 6.3 1.17
183 INT47507 Negative_regulation of Gene_expression of Adh1 1 0.11 0.42 1.17
184 INT103043 Binding of PDE5A 16 0.37 7.79 1.12
185 INT49258 Negative_regulation of Positive_regulation of EDN1 10 0.43 7.24 1.12
186 INT106339 Positive_regulation of Phosphorylation of Insr 1 0.49 0 1.12
187 INT123144 Positive_regulation of DEFB1 4 0.45 2.12 1.08
188 INT32354 Negative_regulation of Regulation of Insr 3 0.33 0.13 1.08
189 INT3609 Regulation of Gene_expression of Cbr1 1 0.27 0.74 1.08
190 INT10625 Regulation of Positive_regulation of Avp 4 0.44 1.06 1.04
191 INT25718 Negative_regulation of Negative_regulation of Avp 4 0.58 0.5 1.02
192 INT66862 Regulation of Esr2 3 0.24 1.56 1.01
193 INT69803 Regulation of Localization of Edn1 3 0.62 0.79 0.98
194 INT21940 Positive_regulation of CALR 15 0.40 17.42 0.95
195 INT49255 Protein_catabolism of EDN1 5 0.99 2.66 0.95
196 INT53066 Positive_regulation of Positive_regulation of EPO 4 0.49 2.38 0.95
197 INT69422 Positive_regulation of Negative_regulation of EDN1 2 0.43 0.96 0.95
198 INT94565 Regulation of Regulation of Epo 1 0.07 0.14 0.95
199 INT49254 Transcription of EDN1 5 0.69 2.42 0.94
200 INT17718 Positive_regulation of Gene_expression of Aldh2 3 0.50 0.96 0.94
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