GO:0033590

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Name response to cobalamin
Categary Process
Go Slim No
Go Link GO:0033590
Unique Molecular Interactions 52
Total Molecular Interactions 89
Total Single Events 790
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for response to cobalamin. They are ordered first by their pain relevance and then by number of times they were reported for response to cobalamin. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT356289 Binding of Egfr and Egf 1 0.13 3.02 2.52
2 INT281382 FSCN1 Positive_regulation of Sds 1 0.02 0.84 1.33
3 INT147033 Positive_regulation of Binding of Sds and Accn3 1 0.13 0.73 1.23
4 INT147032 Binding of Sds and Accn3 1 0.09 0.73 1.22
5 INT55162 Binding of NFKB1 and RELA 10 0.30 2.82 1.18
6 INT147447 ADCYAP1 Regulation of Localization of RELA 1 0.50 1.12 1.15
7 INT161455 Mmp7 Positive_regulation of Egfr 1 0.03 0.19 0.92
8 INT322397 Egfr Positive_regulation of Adarb1 1 0.00 0.08 0.8
9 INT228494 Binding of Ncoa5 and Rela 1 0.00 1.58 0.72
10 INT153123 NFKBIA Negative_regulation of Phosphorylation of RELA 1 0.03 2.01 0.71
11 INT298728 Akt1 Positive_regulation of Rela 1 0.01 1.03 0.67
12 INT281374 Tcf21 Positive_regulation of Gene_expression of Sds 1 0.03 0 0.51
13 INT107704 IL1B Positive_regulation of Localization of RELA 1 0.02 0.13 0.41
14 INT265015 Pgr Positive_regulation of Sds 1 0.04 0.49 0.37
15 INT129291 Positive_regulation of OPRM1 Positive_regulation of Phosphorylation of RELA 1 0.06 0.27 0.28
16 INT63988 Cntf Regulation of Positive_regulation of Sds 1 0.22 0 0.28
17 INT143950 Negative_regulation of NFKB1 Positive_regulation of Gene_expression of RELA 1 0.45 0.46 0.23
18 INT340447 Negative_regulation of IRF6 Positive_regulation of RELA 1 0.00 0.87 0.18
19 INT340448 IRF6 Positive_regulation of RELA 1 0.00 0.86 0.17
20 INT139821 ZNF833P Negative_regulation of Localization of RELA 1 0.00 0.11 0.15
21 INT178351 Binding of Il6 and Hp 1 0.00 0.61 0.14
22 INT280809 Binding of gr and Rela 1 0.00 0 0.13
23 INT55163 Binding of RELA and WRAP53 1 0.01 0.05 0.1
24 INT356272 Egf Negative_regulation of Gene_expression of Egfr 1 0.15 0.2 0.1
25 INT292328 Binding of Sds and Mb 1 0.11 0.24 0.1
26 INT243685 NDUFA2 Negative_regulation of Localization of RELA 1 0.07 0 0.09
27 INT290906 Shh Positive_regulation of Egfr 1 0.23 0 0.08
28 INT208219 RELA Regulation of IRF6 1 0.00 0.07 0.07
29 INT292334 Binding of Sds and Fig4 1 0.02 0.07 0.05
30 INT340271 Fig4 Positive_regulation of Localization of RELA 1 0.01 0.68 0.04
31 INT340276 Tnfsf11 Positive_regulation of Localization of RELA 1 0.02 0.58 0.03
32 INT315052 Binding of IL8 and RELA 1 0.07 0.34 0
33 INT95305 RELA Positive_regulation of Nfkb1 1 0.00 0.08 0
34 INT315053 Negative_regulation of AKT1 Positive_regulation of Binding of RELA 1 0.10 0.12 0
35 INT95308 Binding of RELA and Nfkb1 1 0.00 0.08 0
36 INT170586 CD40 Negative_regulation of Positive_regulation of RELA 1 0.12 0.24 0
37 INT95306 Negative_regulation of RELA Positive_regulation of Nfkb1 1 0.00 0.08 0
38 INT315064 Binding of RELA and PAR4 1 0.08 0.45 0
39 INT292329 Binding of Sds and LOC360919 1 0.01 0.08 0
40 INT347353 Binding of Ldha and Sds 1 0.12 0.07 0
41 INT161454 Mmp8 Positive_regulation of Egfr 1 0.36 0 0
42 INT55165 Binding of REL and RELA 1 0.16 0.18 0
43 INT170590 RELA Negative_regulation of Gene_expression of ICAM1 1 0.42 0.49 0
44 INT292159 Binding of NFKB2 and RELA 1 0.02 0.4 0
45 INT170588 RELA Regulation of Gene_expression of ICAM1 1 0.26 0 0
46 INT55166 Binding of PROC and RELA 1 0.01 0.09 0
47 INT95307 Negative_regulation of Binding of RELA and Nfkb1 1 0.00 0.08 0
48 INT95304 Positive_regulation of Binding of RELA and Nfkb1 1 0.00 0.08 0
49 INT347352 Negative_regulation of Binding of Ldha and Sds 1 0.14 0.07 0
50 INT315062 Positive_regulation of Binding of RELA and PAR4 1 0.11 0.12 0
51 INT315051 AKT1 Regulation of Localization of RELA 1 0.09 0.07 0
52 INT197814 Binding of MEN1 and RELA 1 0.42 0.07 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for response to cobalamin. They are ordered first by their pain relevance and then by number of times they were reported in response to cobalamin. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT19948 Gene_expression of Sds 34 0.63 14.69 15.44
2 INT3969 Positive_regulation of Sds 27 0.69 7.52 12.31
3 INT66213 Localization of RELA 63 0.78 14.71 8.77
4 INT4159 Gene_expression of Hp 33 0.72 12.49 8.39
5 INT3401 Positive_regulation of Hp 22 0.69 16.33 7.97
6 INT53685 Regulation of Sds 10 0.39 5.39 7.22
7 INT1317 Negative_regulation of Sds 23 0.48 6.97 5.03
8 INT55171 Gene_expression of RELA 80 0.75 17.17 4.47
9 INT120715 Positive_regulation of Egfr 15 0.68 5.53 3.77
10 INT35634 Positive_regulation of Gene_expression of Sds 10 0.37 3.23 3.69
11 INT119506 Negative_regulation of Egfr 32 0.55 23.75 3.67
12 INT73557 Positive_regulation of RELA 57 0.46 8.7 3.43
13 INT124954 Gene_expression of Egfr 26 0.75 15.08 3.12
14 INT66212 Negative_regulation of Localization of RELA 13 0.57 2.48 3.09
15 INT21299 Negative_regulation of Hp 14 0.44 10.97 2.97
16 INT15288 Regulation of Hp 11 0.60 3.68 2.89
17 INT153221 Positive_regulation of Rela 5 0.16 2.16 2.72
18 INT281368 Regulation of Gene_expression of Sds 3 0.13 1.66 2.31
19 INT123530 Phosphorylation of RELA 9 0.80 3.46 1.99
20 INT124953 Negative_regulation of Gene_expression of Egfr 6 0.42 1.97 1.75
21 INT55169 Binding of RELA 40 0.36 4.91 1.74
22 INT108875 Positive_regulation of Localization of RELA 9 0.49 1.43 1.72
23 INT265010 Negative_regulation of Gene_expression of Sds 4 0.20 1.07 1.69
24 INT110252 Positive_regulation of Gene_expression of RELA 29 0.49 6.36 1.31
25 INT153220 Negative_regulation of Positive_regulation of Rela 1 0.09 0.31 1.31
26 INT126706 Transcription of Sds 3 0.36 0.59 1.14
27 INT72526 Regulation of Regulation of Sds 1 0.26 0.78 1.1
28 INT3402 Positive_regulation of Positive_regulation of Hp 2 0.49 1.05 1
29 INT248678 Gene_expression of Rela 4 0.16 2.35 0.9
30 INT144415 Regulation of Positive_regulation of Egfr 2 0.27 0.42 0.86
31 INT144416 Regulation of Egfr 5 0.57 4.97 0.83
32 INT144414 Positive_regulation of Positive_regulation of Egfr 1 0.49 0.65 0.8
33 INT35804 Regulation of Gene_expression of Hp 3 0.34 0.68 0.75
34 INT108874 Regulation of Localization of RELA 5 0.44 1.09 0.61
35 INT178715 Localization of Rela 1 0.11 0.86 0.59
36 INT91744 Positive_regulation of Positive_regulation of Sds 1 0.22 0.17 0.59
37 INT320644 Binding of Egfr 7 0.34 5.9 0.56
38 INT265007 Positive_regulation of Phosphorylation of Sds 1 0.30 0.52 0.54
39 INT265009 Phosphorylation of Sds 1 0.36 0.51 0.53
40 INT73559 Negative_regulation of Positive_regulation of RELA 2 0.36 1.37 0.49
41 INT63985 Negative_regulation of Negative_regulation of Sds 2 0.40 0.8 0.48
42 INT265005 Localization of Sds 4 0.35 1.15 0.47
43 INT19212 Positive_regulation of Gene_expression of Hp 5 0.15 1.47 0.46
44 INT142943 Phosphorylation of Egfr 5 0.81 1.56 0.45
45 INT142942 Positive_regulation of Phosphorylation of Egfr 4 0.68 1.52 0.45
46 INT265008 Regulation of Transcription of Sds 1 0.20 0.23 0.44
47 INT183920 Localization of Hp 1 0.29 0.93 0.33
48 INT349651 Positive_regulation of Gene_expression of Rela 1 0.03 1.46 0.33
49 INT73555 Negative_regulation of RELA 5 0.41 0.57 0.32
50 INT45869 Negative_regulation of Gene_expression of Hp 1 0.42 0.65 0.31
51 INT183911 Negative_regulation of Phosphorylation of Hp 1 0.17 0.86 0.3
52 INT129297 Positive_regulation of Phosphorylation of RELA 1 0.24 0.33 0.29
53 INT121077 Binding of Sds 20 0.25 1.41 0.28
54 INT63987 Regulation of Positive_regulation of Sds 1 0.41 0 0.28
55 INT183919 Positive_regulation of Phosphorylation of Hp 1 0.20 0.8 0.28
56 INT183914 Phosphorylation of Hp 1 0.32 0.78 0.27
57 INT170600 Negative_regulation of Gene_expression of RELA 16 0.39 1.29 0.25
58 INT170596 Regulation of RELA 4 0.41 0.39 0.25
59 INT170594 Regulation of Gene_expression of RELA 6 0.41 0.15 0.22
60 INT170607 Positive_regulation of Positive_regulation of RELA 4 0.46 1.49 0.21
61 INT170602 Positive_regulation of Binding of RELA 5 0.46 0.32 0.2
62 INT153462 Regulation of Rela 1 0.44 0.98 0.15
63 INT144682 Negative_regulation of Regulation of Egfr 1 0.43 0.41 0.15
64 INT299514 Localization of Egfr 2 0.37 0.38 0.14
65 INT233419 Negative_regulation of Positive_regulation of Egfr 2 0.40 0.97 0.12
66 INT170597 Negative_regulation of Regulation of RELA 1 0.39 0 0.11
67 INT219647 Negative_regulation of Negative_regulation of Egfr 1 0.19 0.13 0.1
68 INT170593 Transcription of RELA 3 0.63 0.92 0.08
69 INT294736 Positive_regulation of Positive_regulation of Rela 1 0.03 1.04 0.08
70 INT248672 Binding of Rela 1 0.05 0.38 0.06
71 INT299512 Regulation of Localization of Egfr 1 0.13 0.11 0.06
72 INT205021 Positive_regulation of Gene_expression of Egfr 3 0.64 4.15 0.05
73 INT186335 Protein_catabolism of RELA 2 0.86 0.71 0
74 INT312059 Negative_regulation of Binding of RELA 1 0.43 0 0
75 INT347351 Negative_regulation of Binding of Sds 1 0.20 0.07 0
76 INT328748 Positive_regulation of Binding of Sds 1 0.25 0.16 0
77 INT50455 Positive_regulation of Regulation of Hp 1 0.08 0.08 0
78 INT186330 Positive_regulation of Protein_catabolism of RELA 1 0.49 0.55 0
79 INT288036 Negative_regulation of Phosphorylation of RELA 1 0.07 0.13 0
80 INT292351 Regulation of Binding of Sds 1 0.13 0 0
81 INT288035 Regulation of Binding of RELA 1 0.04 0 0
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