GO:0033603

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Name positive regulation of dopamine secretion
Categary Process
Go Slim No
Go Link GO:0033603
Unique Molecular Interactions 76
Total Molecular Interactions 97
Total Single Events 694
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of dopamine secretion. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of dopamine secretion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT166134 Binding of Cxcl12 and Cxcr4 3 0.49 5.69 3.17
2 INT108129 GDNF Regulation of Gene_expression of GRHL3 1 0.21 0.39 1.71
3 INT149844 Negative_regulation of Cxcl12 Negative_regulation of C19orf10 1 0.16 0.45 1.26
4 INT149845 Cxcl12 Negative_regulation of C19orf10 1 0.16 0.45 1.24
5 INT253999 Binding of Cxcl12 and Mif 1 0.41 2.26 1.22
6 INT105109 Cxcl12 Positive_regulation of JUN 1 0.01 1.07 1.05
7 INT166135 Regulation of Binding of Cxcl12 and Cxcr4 1 0.30 0.9 0.91
8 INT253992 Cxcl12 Positive_regulation of Mif 1 0.46 1.31 0.88
9 INT254004 Cxcl12 Positive_regulation of Cxcr4 1 0.47 1.29 0.86
10 INT253995 Binding of Cxcl12 and Cyp3a23/3a1 1 0.06 1.28 0.85
11 INT108128 GDNF Regulation of Localization of GRHL3 1 0.24 0.18 0.83
12 INT253998 Cyp3a23/3a1 Positive_regulation of Binding of Cxcl12 1 0.10 0.65 0.55
13 INT253990 Cyp3a23/3a1 Positive_regulation of Cxcl12 1 0.09 0.65 0.55
14 INT155254 Col4a4 Regulation of Rtn4 1 0.00 0 0.54
15 INT125086 LPA Positive_regulation of Rtn4 1 0.00 0.36 0.54
16 INT105110 Cxcl12 Positive_regulation of NFKB1 1 0.06 0.54 0.53
17 INT105108 Negative_regulation of Cxcl12 Positive_regulation of NFKB1 1 0.05 0.54 0.53
18 INT181441 Csf2 Positive_regulation of Cxcl12 1 0.02 1.69 0.39
19 INT322964 Binding of IL8 and Cxcl12 1 0.30 0.2 0.32
20 INT69362 Binding of Pnoc and Rtn4 1 0.01 0 0.31
21 INT333246 Binding of Cxcr4 and Cxcl12 3 0.34 0.99 0.27
22 INT141545 Binding of Bace1 and Rtn4 1 0.00 0.45 0.27
23 INT141550 Binding of Rtn4r and Rtn4 1 0.00 0.46 0.26
24 INT155158 Agtr2 Regulation of Rtn4 1 0.00 0.1 0.22
25 INT78263 Npy Positive_regulation of Npy2r 1 0.04 0 0.21
26 INT253991 Negative_regulation of Binding of Cxcl12 and Cxcr4 1 0.43 0.41 0.21
27 INT333250 Binding of Cxcr7 and Cxcl12 1 0.19 1.39 0.18
28 INT353361 Positive_regulation of Binding of Cxcr4 and Cxcl12 1 0.46 0 0.17
29 INT333255 Cxcl12 Regulation of Mcl1 1 0.12 1.12 0.15
30 INT333241 Cxcl12 Regulation of Bcl2l11 1 0.18 1.11 0.15
31 INT353359 Binding of Cxcl12 and Regulation of Nes 1 0.25 0.3 0.15
32 INT353360 Binding of Cxcl12 and Positive_regulation of Gene_expression of Hist1h3f 1 0.03 0.3 0.15
33 INT204996 Binding of Park7 and Pink1 2 0.34 1.09 0.11
34 INT333242 Bcl2l11 Positive_regulation of Gene_expression of Cxcl12 1 0.18 1.48 0.1
35 INT204993 Eri1 Positive_regulation of Gene_expression of Pink1 1 0.22 0.61 0.08
36 INT333251 Binding of Bcl2l11 and Cxcl12 1 0.14 1.74 0.08
37 INT249968 Cxcr4 Positive_regulation of Cxcl12 1 0.17 0.55 0.08
38 INT333256 Gene_expression of Cxcl12 Negative_regulation of Ptk2b 1 0.10 0.99 0.07
39 INT333260 Gene_expression of Cxcl12 Negative_regulation of Gene_expression of Ptk2 1 0.21 1 0.07
40 INT333247 Gene_expression of Cxcl12 Negative_regulation of Pxn 1 0.09 1 0.07
41 INT333243 Gene_expression of Cxcl12 Negative_regulation of Bcar1 1 0.15 1 0.07
42 INT333257 Gene_expression of Cxcl12 Negative_regulation of Ptk2 1 0.21 1 0.07
43 INT204999 Hmmr Positive_regulation of Pink1 1 0.01 0.58 0.06
44 INT317245 Binding of Npy2r and Pyy 1 0.09 0 0.05
45 INT331227 Binding of Becn1 and Pink1 1 0.03 1.13 0.05
46 INT317246 Binding of Npy2r and Npy 1 0.08 0 0.05
47 INT333254 Binding of Mcl1 and Cxcl12 1 0.10 0.88 0.04
48 INT333244 Positive_regulation of Binding of Mcl1 and Cxcl12 1 0.13 0.88 0.04
49 INT333249 Cxcl12 Positive_regulation of Positive_regulation of Bak1 1 0.30 0.32 0.03
50 INT342725 Pink1 Positive_regulation of Phosphorylation of Park2 1 0.29 0.62 0
51 INT342730 Pink1 Positive_regulation of Phosphorylation of Trap1 1 0.17 0.98 0
52 INT342737 Pink1 Positive_regulation of HTRA2 1 0.29 0.58 0
53 INT203418 Enc1 Negative_regulation of Rtn4 1 0.08 0.58 0
54 INT333258 Gene_expression of Cxcl12 Positive_regulation of Positive_regulation of Bak1 1 0.15 0.55 0
55 INT115368 Binding of GDNF and RAPGEF5 1 0.32 0 0
56 INT342728 Pink1 Positive_regulation of Trap1 1 0.17 0.98 0
57 INT203406 Cap2 Negative_regulation of Rtn4 1 0.07 0.59 0
58 INT342731 Pink1 Regulation of Localization of Gfm1 1 0.00 0.61 0
59 INT203410 Vsnl1 Negative_regulation of Rtn4 1 0.18 0.58 0
60 INT317300 Binding of Park2 and Pink1 1 0.48 1.23 0
61 INT342727 Pink1 Positive_regulation of Park2 1 0.29 0.62 0
62 INT299130 Cxcl12 Positive_regulation of Gene_expression of Fgf2 1 0.15 0.38 0
63 INT299140 Cxcl12 Positive_regulation of Transcription of VEGFA 1 0.03 0.38 0
64 INT342736 Pink1 Positive_regulation of Phosphorylation of HTRA2 1 0.29 0.58 0
65 INT333248 Bcl2l11 Regulation of Gene_expression of Cxcl12 1 0.11 0.52 0
66 INT240271 Binding of GDNF and RET 1 0.09 1.04 0
67 INT317307 Binding of Hsp90aa1 and Pink1 1 0.12 0.56 0
68 INT204995 Ppp1r15b Regulation of Gene_expression of Pink1 1 0.01 0.97 0
69 INT299129 Cxcl12 Positive_regulation of Transcription of Fgf2 1 0.16 0.38 0
70 INT317319 Binding of Trap1 and Pink1 1 0.26 2.67 0
71 INT203396 Mllt11 Negative_regulation of Rtn4 1 0.09 0.58 0
72 INT203399 Olfm1 Negative_regulation of Rtn4 1 0.09 0.58 0
73 INT204994 Positive_regulation of Hras1 Positive_regulation of Gene_expression of Pink1 1 0.05 0.97 0
74 INT317306 Binding of Mul1 and Pink1 1 0.01 0.62 0
75 INT342729 Pink1 Regulation of Phosphorylation of Trap1 1 0.09 0.48 0
76 INT317311 Binding of Cdc37 and Pink1 1 0.13 0.56 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of dopamine secretion. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of dopamine secretion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5923 Negative_regulation of Rtn4 50 0.36 24.19 27.2
2 INT56239 Positive_regulation of Rtn4 20 0.26 14.05 18.8
3 INT5922 Gene_expression of Rtn4 27 0.48 12.7 17.86
4 INT53070 Regulation of Rtn4 15 0.22 9.35 13.77
5 INT222233 Gene_expression of Cxcl12 42 0.69 32.64 10.13
6 INT21952 Gene_expression of GDNF 42 0.78 20.32 9.62
7 INT126478 Gene_expression of Cxcl12 78 0.77 58.69 8.01
8 INT136309 Positive_regulation of Cxcl12 24 0.62 12.45 5.58
9 INT75546 Transcription of Rtn4 1 0.06 2.87 5.03
10 INT204971 Gene_expression of Pink1 42 0.77 23.95 4.75
11 INT253983 Binding of Cxcl12 8 0.43 5.33 3.71
12 INT88008 Positive_regulation of Gene_expression of GDNF 14 0.70 8.9 3.61
13 INT156676 Gene_expression of Rtn4 14 0.65 5.78 3.16
14 INT78253 Gene_expression of Npy2r 7 0.77 1.49 2.89
15 INT181386 Positive_regulation of Cxcl12 12 0.69 15.35 2.84
16 INT253982 Positive_regulation of Binding of Cxcl12 1 0.45 3.85 2.6
17 INT130638 Regulation of Cxcl12 6 0.34 2.91 2.44
18 INT129742 Regulation of Positive_regulation of Rtn4 2 0.05 2.51 2.33
19 INT57664 Gene_expression of Npy2r 4 0.19 1.41 2.26
20 INT88006 Positive_regulation of GDNF 5 0.45 2.55 2.14
21 INT222230 Positive_regulation of Gene_expression of Cxcl12 11 0.59 5.26 2.13
22 INT297679 Positive_regulation of Gene_expression of Cxcl12 6 0.69 8.02 2.02
23 INT253972 Positive_regulation of Positive_regulation of Cxcl12 1 0.45 3.22 1.71
24 INT222227 Localization of Cxcl12 5 0.64 1.61 1.59
25 INT21951 Negative_regulation of Gene_expression of GDNF 5 0.43 2.82 1.57
26 INT254252 Localization of Cxcl12 9 0.76 7.17 1.49
27 INT66527 Positive_regulation of Npy2r 2 0.31 0.47 1.44
28 INT235907 Regulation of Negative_regulation of Rtn4 1 0.07 2.93 1.42
29 INT108130 Localization of GDNF 3 0.74 1.36 1.38
30 INT5920 Binding of Rtn4 6 0.36 0.66 1.21
31 INT163963 Negative_regulation of Transcription of Rtn4 1 0.03 0.45 1.06
32 INT211294 Binding of Cxcl12 4 0.45 2.89 1.05
33 INT66526 Regulation of Positive_regulation of Npy2r 1 0.20 0 0.96
34 INT80315 Binding of Npy2r 2 0.48 0.53 0.95
35 INT222231 Transcription of Cxcl12 4 0.55 2.25 0.91
36 INT104333 Negative_regulation of Positive_regulation of Rtn4 1 0.03 0.42 0.84
37 INT80316 Positive_regulation of Npy2r 3 0.31 0.28 0.78
38 INT204969 Negative_regulation of Pink1 1 0.58 7.03 0.75
39 INT104457 Negative_regulation of Gene_expression of Rtn4 1 0.01 0.64 0.71
40 INT300848 Negative_regulation of Cxcl12 3 0.40 2.29 0.69
41 INT128728 Localization of Npy2r 3 0.80 0 0.65
42 INT78255 Transcription of Npy2r 1 0.12 0.59 0.62
43 INT241673 Phosphorylation of GDNF 2 0.79 1.06 0.61
44 INT296589 Localization of Pink1 1 0.08 0.65 0.61
45 INT85138 Binding of GDNF 6 0.37 2.01 0.58
46 INT333232 Negative_regulation of Gene_expression of Cxcl12 4 0.42 3.35 0.57
47 INT80317 Positive_regulation of Binding of Npy2r 1 0.16 0.34 0.56
48 INT222238 Regulation of Localization of Cxcl12 1 0.22 0.6 0.55
49 INT136310 Negative_regulation of Cxcl12 3 0.37 3.29 0.51
50 INT280914 Positive_regulation of Localization of Cxcl12 3 0.44 3.99 0.47
51 INT281148 Negative_regulation of Transcription of Cxcl12 1 0.26 1.12 0.47
52 INT281140 Regulation of Binding of Cxcl12 1 0.28 0.93 0.47
53 INT281149 Positive_regulation of Localization of Cxcl12 1 0.31 0.42 0.45
54 INT5921 Positive_regulation of Gene_expression of Rtn4 1 0.26 0.35 0.42
55 INT88012 Regulation of Gene_expression of GDNF 2 0.43 0.48 0.31
56 INT274228 Positive_regulation of Positive_regulation of Cxcl12 4 0.44 2.82 0.23
57 INT235908 Localization of Rtn4 1 0.08 0.25 0.23
58 INT299139 Positive_regulation of Transcription of Cxcl12 1 0.37 0.28 0.21
59 INT64107 Negative_regulation of Npy2r 1 0.12 0 0.2
60 INT226977 Positive_regulation of Gene_expression of Rtn4 1 0.51 1.1 0.19
61 INT333239 Regulation of Gene_expression of Cxcl12 1 0.43 3.48 0.19
62 INT204987 Binding of Pink1 3 0.37 4.72 0.17
63 INT88007 Regulation of GDNF 2 0.34 0.82 0.16
64 INT204983 Positive_regulation of Gene_expression of Pink1 1 0.50 2.03 0.16
65 INT253969 Regulation of Gene_expression of Cxcl12 3 0.40 1.56 0.15
66 INT78262 Transcription of Npy2r 1 0.07 0 0.15
67 INT204975 Positive_regulation of Pink1 7 0.69 5.17 0.14
68 INT253981 Negative_regulation of Gene_expression of Cxcl12 3 0.39 1.7 0.13
69 INT233555 Regulation of Cxcl12 2 0.43 4.12 0.13
70 INT216038 Binding of Rtn4 1 0.40 0.8 0.13
71 INT250408 Positive_regulation of Gene_expression of Npy2r 1 0.08 0.09 0.12
72 INT88013 Transcription of GDNF 2 0.40 0.22 0.11
73 INT88011 Positive_regulation of Transcription of GDNF 1 0.35 0.22 0.11
74 INT299136 Protein_catabolism of Cxcl12 1 0.56 1.15 0.09
75 INT353357 Regulation of Positive_regulation of Cxcl12 1 0.27 0.62 0.08
76 INT333206 Negative_regulation of Localization of Cxcl12 1 0.41 1.11 0.08
77 INT333233 Negative_regulation of Positive_regulation of Cxcl12 1 0.41 1.11 0.08
78 INT216029 Positive_regulation of Binding of Rtn4 1 0.38 0.33 0.06
79 INT216031 Positive_regulation of Rtn4 1 0.57 0.79 0.03
80 INT204981 Positive_regulation of Protein_catabolism of Pink1 1 0.46 1.43 0
81 INT342712 Phosphorylation of Pink1 1 0.32 0.62 0
82 INT204979 Protein_catabolism of Pink1 1 0.99 1.43 0
83 INT76871 Regulation of Npy2r 1 0.19 0 0
84 INT342724 Transcription of Pink1 1 0.35 0.31 0
85 INT317282 Regulation of Pink1 1 0.40 1.26 0
86 INT204988 Regulation of Gene_expression of Pink1 1 0.45 1.91 0
87 INT333210 Regulation of Localization of Cxcl12 1 0.58 0.56 0
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