GO:0033630

From wiki-pain
Jump to: navigation, search
Name positive regulation of cell adhesion mediated by integrin
Categary Process
Go Slim No
Go Link GO:0033630
Unique Molecular Interactions 72
Total Molecular Interactions 80
Total Single Events 737
Pain Genes Associated 14

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of cell adhesion mediated by integrin. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of cell adhesion mediated by integrin. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT180814 Binding of Ret and Gdnf 1 0.01 1.31 1.17
2 INT147507 Binding of Ret and Gtf3a 1 0.03 0.81 0.92
3 INT147505 Binding of Ret and Gdnf 1 0.27 0.81 0.92
4 INT181437 Binding of Ccr7 and Ccl21b 1 0.01 2.23 0.87
5 INT181452 Binding of Ccl19 and Ccl21b 1 0.02 2.22 0.86
6 INT161945 TGFB2 Positive_regulation of TGFBR1 1 0.08 0.99 0.76
7 INT161949 TGFB2 Positive_regulation of Gene_expression of Ngf 1 0.21 0.97 0.74
8 INT338390 Thim Regulation of Gene_expression of Ret 1 0.02 0.43 0.65
9 INT114845 RET Regulation of Gene_expression of Lgals1 1 0.02 0.84 0.65
10 INT280895 Runx1 Positive_regulation of Gene_expression of Ret 2 0.33 0.2 0.58
11 INT98034 Binding of Ret and Trpv1 1 0.43 0.42 0.58
12 INT242613 Binding of Gfra2 and Ret 1 0.02 0 0.52
13 INT242628 Binding of Gfra1 and Ret 1 0.03 0 0.46
14 INT242615 Ret Positive_regulation of Gene_expression of Gfra1 1 0.04 0 0.46
15 INT72089 TGFB2 Positive_regulation of POMC 1 0.11 0 0.46
16 INT242596 Binding of Ntrk1 and Ret 1 0.12 0 0.46
17 INT324802 Binding of Cd24a and Siglecg 1 0.03 1.34 0.4
18 INT242607 Negative_regulation of Ntrk1 Positive_regulation of Ret 1 0.16 0 0.39
19 INT208571 CCL21 Positive_regulation of Gene_expression of CCL16 1 0.51 0.63 0.38
20 INT223470 Ret Regulation of Ntrk1 1 0.21 0 0.36
21 INT7893 Binding of Oprm1 and Ccl21b 1 0.00 0.08 0.35
22 INT148240 Binding of Kit and Ret 1 0.24 0.44 0.35
23 INT252292 CCL21 Regulation of Binding of Mthfd1 1 0.03 0.41 0.33
24 INT225021 PDGFB Positive_regulation of Ccl21 1 0.10 0.07 0.3
25 INT225026 PDGFB Positive_regulation of Gene_expression of Ccl21 1 0.10 0.07 0.3
26 INT245563 Negative_regulation of Runx1 Regulation of Ret 1 0.39 0.76 0.29
27 INT245556 Runx1 Regulation of Ret 1 0.56 0.76 0.29
28 INT209851 TGFB2 Negative_regulation of Gene_expression of CD36 1 0.16 0.16 0.21
29 INT324824 Positive_regulation of Binding of Cd24a and Siglecg 1 0.03 0.68 0.2
30 INT64964 Binding of Alb and Cd24 1 0.02 0.2 0.2
31 INT324822 Binding of Cd24a and Hsp90aa1 1 0.10 0.71 0.19
32 INT324797 Binding of Cd24a and Hmgb1 1 0.19 0.66 0.19
33 INT242632 Ret Positive_regulation of Gene_expression of Trpa1 1 0.33 0.09 0.18
34 INT276301 Binding of CCL21 and CXCL13 1 0.04 1.85 0.18
35 INT96518 Regulation of Gdnf Positive_regulation of Ret 1 0.00 0.23 0.11
36 INT258527 Binding of BRAF and RET 1 0.21 1.49 0.11
37 INT64966 Binding of AGFG1 and Cd24 1 0.00 0.1 0.1
38 INT275451 Binding of ZAP70 and Syk 1 0.02 0.12 0.1
39 INT275450 Binding of STAM and Syk 1 0.00 0.12 0.1
40 INT149178 IL4 Negative_regulation of Positive_regulation of TGFB2 1 0.15 0.29 0.1
41 INT96519 Gdnf Positive_regulation of Ret 1 0.00 0.22 0.1
42 INT242627 Ngf Positive_regulation of Gene_expression of Ret 1 0.32 0.1 0.1
43 INT265388 CCL21 Positive_regulation of Gene_expression of CXCL9 1 0.13 0.88 0.1
44 INT258522 Binding of DDR1 and RET 1 0.03 1.05 0.1
45 INT265389 CCL21 Positive_regulation of Gene_expression of CXCL10 1 0.16 0.88 0.1
46 INT242594 Binding of Gdnf and Ret 1 0.21 0 0.08
47 INT225023 PDGFB Regulation of Transcription of Ccl21 1 0.11 0 0.06
48 INT242636 Ret Positive_regulation of Gene_expression of Slc18a3 1 0.20 0 0.06
49 INT225022 PDGFB Regulation of Ccl21 1 0.11 0 0.06
50 INT137870 Binding of Artn and Ret 1 0.25 0.16 0.05
51 INT345245 Adam9 Regulation of Adam10 1 0.09 0.18 0.05
52 INT199159 Binding of RET and Pheo 1 0.04 1.42 0.03
53 INT272528 THBS1 Positive_regulation of TGFB2 1 0.09 0.64 0.03
54 INT211883 Binding of RET and CDCP1 1 0.00 2.12 0
55 INT289301 Binding of CD59 and Cd24a 1 0.02 1.06 0
56 INT233267 Hoxa10 Regulation of Itgb3 1 0.15 0.14 0
57 INT314862 Binding of Ltbp3 and Tgfb2 1 0.24 0.52 0
58 INT223471 Dok4 Regulation of Ret 1 0.30 0.17 0
59 INT240271 Binding of GDNF and RET 1 0.09 1.04 0
60 INT242620 Tg(CAG-EGFP)D4Nagy Negative_regulation of Ret 1 0.02 0 0
61 INT233270 Meis1 Regulation of Gene_expression of Itgb3 1 0.47 0 0
62 INT154173 Binding of SIPA1 and SYK 1 0.16 0.46 0
63 INT242619 Ret Negative_regulation of Transcription of Slc18a3 1 0.18 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of cell adhesion mediated by integrin. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of cell adhesion mediated by integrin. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT79979 Gene_expression of Ret 94 0.75 19.21 25.51
2 INT108480 Gene_expression of CCL21 53 0.77 37.87 14.42
3 INT108479 Positive_regulation of CCL21 18 0.67 19.93 10.76
4 INT64849 Gene_expression of Ret 24 0.75 14.36 9.1
5 INT242569 Positive_regulation of Ret 17 0.55 3.61 3.54
6 INT111482 Gene_expression of Cd24a 23 0.72 13.74 3.37
7 INT182224 Binding of CCL21 6 0.34 5.91 2.54
8 INT38631 Positive_regulation of Ret 8 0.39 3.23 2.52
9 INT108483 Positive_regulation of Gene_expression of CCL21 7 0.69 5.76 2.45
10 INT63333 Gene_expression of RET 24 0.76 30.09 2.41
11 INT242548 Regulation of Gene_expression of Ret 7 0.49 1.2 2.33
12 INT50392 Regulation of Ret 6 0.54 3.51 2.22
13 INT242551 Negative_regulation of Gene_expression of Ret 5 0.41 1.01 2.21
14 INT102896 Binding of Ret 8 0.35 1.55 2.03
15 INT181368 Gene_expression of Ccl21b 1 0.03 3.48 2.01
16 INT177509 Regulation of CCL21 6 0.45 5.43 1.66
17 INT221059 Negative_regulation of CCL21 5 0.28 2.48 1.58
18 INT145921 Localization of CCL21 4 0.73 2.41 1.58
19 INT242572 Positive_regulation of Gene_expression of Ret 6 0.40 0.29 1.56
20 INT44746 Localization of Ret 3 0.48 1.23 1.28
21 INT223448 Localization of Ret 2 0.60 0.58 1.23
22 INT109396 Negative_regulation of RET 12 0.42 14.92 1.06
23 INT181367 Negative_regulation of Ccl21b 1 0.01 1.72 0.98
24 INT208932 Regulation of Ret 6 0.49 1.49 0.97
25 INT81878 Gene_expression of TGFB2 3 0.42 2.02 0.97
26 INT2425 Negative_regulation of Ret 3 0.58 1.77 0.94
27 INT92002 Transcription of Ret 3 0.43 1.58 0.9
28 INT83461 Binding of RET 8 0.47 9.7 0.87
29 INT126572 Positive_regulation of SYK 3 0.67 2.98 0.83
30 INT340843 Binding of Cd24a 1 0.02 0.24 0.8
31 INT108044 Phosphorylation of Syk 3 0.25 1.39 0.77
32 INT93737 Gene_expression of Tgfb2 2 0.03 1.16 0.77
33 INT93736 Positive_regulation of Gene_expression of Tgfb2 2 0.02 1.16 0.77
34 INT79784 Positive_regulation of RET 15 0.57 17.43 0.71
35 INT114842 Localization of RET 3 0.71 5.98 0.71
36 INT66940 Regulation of RET 7 0.52 5.61 0.69
37 INT145922 Positive_regulation of Positive_regulation of CCL21 1 0.39 0.82 0.69
38 INT181366 Regulation of Ccl21b 1 0.01 0.52 0.69
39 INT115297 Positive_regulation of TGFB2 4 0.29 1.91 0.65
40 INT208591 Negative_regulation of Gene_expression of CCL21 2 0.40 0.92 0.6
41 INT132324 Localization of SYK 2 0.78 1.9 0.59
42 INT278152 Negative_regulation of Syk 1 0.24 1.93 0.59
43 INT115292 Regulation of TGFB2 4 0.17 2.79 0.58
44 INT91993 Regulation of Gene_expression of Ret 3 0.42 2.42 0.55
45 INT132325 Positive_regulation of Localization of SYK 1 0.49 0.56 0.54
46 INT130047 Localization of TGFB2 3 0.16 3.65 0.53
47 INT340842 Regulation of Gene_expression of Cd24a 1 0.42 0.08 0.53
48 INT228248 Gene_expression of Adam9 4 0.45 1.63 0.51
49 INT64961 Binding of Cd24 4 0.15 0.64 0.5
50 INT154180 Negative_regulation of SYK 3 0.43 4.67 0.5
51 INT245546 Negative_regulation of Positive_regulation of Ret 2 0.34 0.89 0.49
52 INT326696 Regulation of Cd24a 2 0.44 0 0.48
53 INT221052 Positive_regulation of Negative_regulation of CCL21 1 0.22 0.85 0.48
54 INT154182 Phosphorylation of SYK 6 0.82 5.54 0.43
55 INT140868 Positive_regulation of Gene_expression of Ret 1 0.50 0.32 0.42
56 INT248931 Positive_regulation of Tgfb2 1 0.03 0 0.4
57 INT154181 Positive_regulation of Phosphorylation of SYK 4 0.70 4.71 0.37
58 INT225008 Gene_expression of Ccl21 1 0.27 0.07 0.36
59 INT154175 Regulation of SYK 2 0.62 1.48 0.34
60 INT225010 Positive_regulation of Ccl21 1 0.20 0.12 0.33
61 INT108043 Negative_regulation of Phosphorylation of Syk 1 0.13 0.53 0.31
62 INT208587 Transcription of CCL21 2 0.49 0.84 0.3
63 INT154559 Positive_regulation of Syk 2 0.20 0.74 0.3
64 INT316692 Regulation of Localization of TGFB2 1 0.03 1.13 0.3
65 INT177508 Regulation of Gene_expression of CCL21 1 0.27 1.23 0.3
66 INT242520 Negative_regulation of Ret 1 0.35 2.49 0.26
67 INT278155 Regulation of Negative_regulation of Syk 1 0.18 0.55 0.26
68 INT125780 Negative_regulation of Itgb3 2 0.39 0.66 0.25
69 INT252723 Gene_expression of SYK 3 0.25 2.67 0.23
70 INT265418 Negative_regulation of Negative_regulation of CCL21 1 0.20 0.32 0.22
71 INT278154 Regulation of Syk 1 0.05 0.98 0.22
72 INT278147 Localization of Syk 1 0.30 0.98 0.22
73 INT91278 Positive_regulation of Itgb3 4 0.31 1.73 0.19
74 INT233246 Localization of Itgb3 3 0.54 0.25 0.17
75 INT239859 Protein_catabolism of Itgb3 1 0.64 0.25 0.17
76 INT154177 Negative_regulation of Phosphorylation of SYK 1 0.43 1.51 0.14
77 INT153553 Positive_regulation of Gene_expression of RET 1 0.67 1.38 0.12
78 INT233217 Gene_expression of Itgb3 16 0.75 0.98 0.11
79 INT275411 Binding of Syk 1 0.09 0.12 0.1
80 INT254742 Gene_expression of Cd24 1 0.11 0.46 0.09
81 INT254732 Localization of Cd24 1 0.12 0.46 0.09
82 INT355318 Positive_regulation of Gene_expression of Cd24a 1 0.47 1.17 0.09
83 INT233253 Regulation of Gene_expression of Itgb3 1 0.41 0.34 0.09
84 INT242576 Positive_regulation of Regulation of Ret 1 0.35 0.09 0.08
85 INT265420 Negative_regulation of Transcription of CCL21 1 0.23 0.52 0.08
86 INT345234 Positive_regulation of Transcription of Adam9 1 0.20 0.19 0.08
87 INT345238 Transcription of Adam9 1 0.23 0.19 0.08
88 INT343551 Positive_regulation of Localization of TGFB2 1 0.10 1.48 0.08
89 INT345241 Localization of Adam9 1 0.30 0.16 0.07
90 INT254740 Negative_regulation of Cd24 1 0.07 0.08 0.07
91 INT251229 Negative_regulation of Tgfb2 1 0.34 0.06 0.07
92 INT153554 Positive_regulation of Binding of RET 1 0.45 0.83 0.07
93 INT225009 Transcription of Ccl21 1 0.24 0 0.06
94 INT225005 Positive_regulation of Transcription of Ccl21 1 0.18 0 0.06
95 INT345239 Positive_regulation of Gene_expression of Adam9 1 0.25 0 0.05
96 INT199153 Phosphorylation of RET 1 0.44 1.73 0.04
97 INT292130 Negative_regulation of Gene_expression of RET 1 0.12 1.37 0.04
98 INT276348 Positive_regulation of Positive_regulation of SYK 1 0.22 0.66 0.04
99 INT258058 Phosphorylation of TGFB2 1 0.08 0.89 0.04
100 INT242574 Positive_regulation of Positive_regulation of Ret 1 0.40 0.12 0.04
101 INT219663 Binding of Itgb3 1 0.08 1.18 0.03
102 INT356267 Binding of Ret 1 0.08 0 0.03
103 INT276371 Positive_regulation of Gene_expression of SYK 1 0.22 0.67 0.03
104 INT233234 Negative_regulation of Gene_expression of Itgb3 3 0.29 0.65 0
105 INT326709 Negative_regulation of Gene_expression of Cd24a 3 0.40 0.86 0
106 INT200854 Transcription of Cd24a 2 0.66 0.4 0
107 INT314821 Binding of Tgfb2 1 0.36 0.51 0
108 INT154178 Binding of SYK 1 0.37 0.46 0
109 INT233231 Regulation of Transcription of Itgb3 1 0.30 0.12 0
110 INT159211 Positive_regulation of Gene_expression of TGFB2 1 0.06 0 0
111 INT355323 Negative_regulation of Cd24a 1 0.40 0.08 0
112 INT233238 Negative_regulation of Localization of Itgb3 1 0.29 0 0
113 INT351109 Transcription of TGFB2 1 0.24 0.94 0
114 INT233251 Regulation of Localization of Itgb3 1 0.30 0 0
115 INT194939 Regulation of Phosphorylation of SYK 1 0.18 0.31 0
116 INT338104 Transcription of RET 1 0.54 0.59 0
117 INT237846 Positive_regulation of Localization of CCL21 1 0.23 0.94 0
118 INT233240 Negative_regulation of Transcription of Itgb3 1 0.29 0 0
119 INT233257 Transcription of Itgb3 1 0.48 0.11 0
120 INT233227 Positive_regulation of Transcription of Itgb3 1 0.47 0.12 0
121 INT233228 Regulation of Itgb3 1 0.30 0 0
122 INT242580 Regulation of Positive_regulation of Ret 1 0.36 0.69 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox