GO:0033754

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Name indoleamine 2,3-dioxygenase activity
Categary Function
Go Slim No
Go Link GO:0033754
Unique Molecular Interactions 42
Total Molecular Interactions 50
Total Single Events 761
Pain Genes Associated 3

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for indoleamine 2,3-dioxygenase activity. They are ordered first by their pain relevance and then by number of times they were reported for indoleamine 2,3-dioxygenase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT142075 IL4 Negative_regulation of Binding of IDO1 1 0.02 2.07 1.19
2 INT142077 TGFB1 Negative_regulation of Binding of IDO1 1 0.15 2.07 1.19
3 INT220051 Fcgr4 Positive_regulation of Gene_expression of Ido1 1 0.01 1.24 0.55
4 INT104447 Ido1 Negative_regulation of Binding of Atp7b 1 0.00 0.68 0.43
5 INT220050 Ctla4 Positive_regulation of Ido1 1 0.31 1.45 0.38
6 INT294115 IDO1 Positive_regulation of PTGER2 1 0.02 0.36 0.31
7 INT270046 Ido1 Positive_regulation of Positive_regulation of Hmox1 1 0.15 0.8 0.27
8 INT355981 IFNAR2 Positive_regulation of IDO1 1 0.01 1.13 0.23
9 INT355985 IDO1 Positive_regulation of Gene_expression of DCPS 1 0.02 1.21 0.23
10 INT220053 Il10 Positive_regulation of Ido1 1 0.14 0.74 0.19
11 INT191337 Binding of IDO1 and GOPC 1 0.01 0.65 0.16
12 INT191338 Binding of TSPO and IDO1 1 0.02 0.65 0.16
13 INT124618 IDO1 Positive_regulation of Gene_expression of GDF15 1 0.03 0.32 0.14
14 INT323345 Ido1 Positive_regulation of Gene_expression of Tlr4 1 0.14 0.69 0.13
15 INT268083 Ido1 Negative_regulation of Tyrp1 1 0.22 0 0.13
16 INT268082 Ido1 Positive_regulation of Gpr35 1 0.04 0 0.13
17 INT293236 IDO1 Regulation of ABCA1 1 0.00 0 0.11
18 INT170330 Regulation of Regulation of Gene_expression of Ido1 1 0.01 0.38 0.08
19 INT226906 Binding of Ido1 and Il6 1 0.07 0.67 0.08
20 INT293233 IDO1 Positive_regulation of ABCA1 1 0.01 0 0.06
21 INT268088 Tdo2 Positive_regulation of Gene_expression of Ido1 1 0.41 0.09 0.04
22 INT170328 Gene_expression of Ido1 Positive_regulation of Hmga2 1 0.01 0.13 0.04
23 INT170337 Gene_expression of Ido1 Positive_regulation of MRXS5 1 0.01 0.12 0.03
24 INT170326 Ido1 Positive_regulation of Cpox 1 0.07 0.12 0.03
25 INT170338 Gene_expression of Ido1 Positive_regulation of IGHD2-15 1 0.02 0.12 0.03
26 INT170327 Ido1 Positive_regulation of Gene_expression of Cpox 1 0.07 0.12 0.03
27 INT293234 Binding of IDO1 and MARVELD1 1 0.01 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for indoleamine 2,3-dioxygenase activity. They are ordered first by their pain relevance and then by number of times they were reported in indoleamine 2,3-dioxygenase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT170308 Gene_expression of Ido1 159 0.75 69.51 15.98
2 INT170295 Positive_regulation of Ido1 40 0.67 28.89 7.61
3 INT142082 Positive_regulation of IDO1 17 0.60 9.46 6.33
4 INT170315 Positive_regulation of Gene_expression of Ido1 50 0.67 25.39 6.06
5 INT11298 Gene_expression of Ido1 6 0.58 6.71 4.85
6 INT191343 Gene_expression of IDO1 23 0.55 11.3 4.81
7 INT170311 Negative_regulation of Ido1 16 0.48 14.47 4.81
8 INT143557 Positive_regulation of Ido1 6 0.40 5.34 4.8
9 INT170323 Regulation of Gene_expression of Ido1 11 0.60 8.74 2.33
10 INT143561 Positive_regulation of Positive_regulation of Ido1 1 0.36 1.84 1.89
11 INT150248 Positive_regulation of Gene_expression of Ido1 2 0.43 2.68 1.77
12 INT191342 Positive_regulation of Gene_expression of IDO1 4 0.36 3.5 1.75
13 INT142081 Binding of IDO1 4 0.21 2.55 1.73
14 INT142078 Negative_regulation of IDO1 3 0.14 2.59 1.23
15 INT220046 Positive_regulation of Negative_regulation of Ido1 1 0.41 2.98 1.12
16 INT88177 Negative_regulation of Ido1 3 0.25 0.51 1.02
17 INT220043 Positive_regulation of Positive_regulation of Ido1 2 0.41 1.94 0.83
18 INT143559 Positive_regulation of Protein_catabolism of Ido1 1 0.29 0.93 0.79
19 INT143560 Protein_catabolism of Ido1 1 0.52 0.93 0.79
20 INT143558 Negative_regulation of Negative_regulation of Ido1 1 0.25 0.49 0.76
21 INT293249 Localization of IDO1 3 0.38 0.77 0.68
22 INT142080 Protein_catabolism of IDO1 2 0.27 1.47 0.55
23 INT293250 Positive_regulation of Localization of IDO1 2 0.24 0.78 0.54
24 INT170299 Negative_regulation of Gene_expression of Ido1 12 0.57 2.59 0.5
25 INT220048 Protein_catabolism of Ido1 1 0.81 1.03 0.47
26 INT270034 Negative_regulation of Positive_regulation of Ido1 1 0.19 2.23 0.42
27 INT270027 Regulation of Positive_regulation of Ido1 1 0.23 1.17 0.39
28 INT170318 Regulation of Ido1 6 0.38 2.63 0.38
29 INT191339 Negative_regulation of Gene_expression of IDO1 2 0.19 0.73 0.3
30 INT198666 Regulation of Gene_expression of IDO1 1 0.05 1.77 0.26
31 INT11299 Binding of Ido1 1 0.31 0.15 0.15
32 INT170320 Binding of Ido1 1 0.36 0.19 0.11
33 INT170297 Positive_regulation of Regulation of Ido1 1 0.39 0.29 0.1
34 INT150250 Transcription of IDO1 2 0.69 0.08 0.09
35 INT294131 Negative_regulation of Transcription of IDO1 1 0.30 0.08 0.09
36 INT294144 Positive_regulation of Positive_regulation of IDO1 1 0.29 0.06 0.09
37 INT339608 Localization of Ido1 1 0.14 0.41 0.08
38 INT150246 Negative_regulation of Gene_expression of Ido1 1 0.07 0 0
39 INT170301 Negative_regulation of Negative_regulation of Ido1 1 0.36 0.32 0
40 INT170310 Transcription of Ido1 1 0.61 0.52 0
41 INT150247 Transcription of Ido1 1 0.10 0 0
42 INT277823 Positive_regulation of Protein_catabolism of IDO1 1 0.15 0.09 0
43 INT150249 Negative_regulation of Transcription of Ido1 1 0.08 0 0
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