GO:0033762

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Name response to glucagon stimulus
Categary Process
Go Slim No
Go Link GO:0033762
Unique Molecular Interactions 55
Total Molecular Interactions 83
Total Single Events 866
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for response to glucagon stimulus. They are ordered first by their pain relevance and then by number of times they were reported for response to glucagon stimulus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT84603 Adrb1 Regulation of Gene_expression of Aqp2 1 0.00 0 0.56
2 INT84600 Binding of Avp and Aqp2 1 0.17 0 0.35
3 INT150050 Mtor Positive_regulation of Rps6kb1 3 0.49 1.44 0.3
4 INT293118 Avp Regulation of Aqp2 1 0.04 0.7 0.27
5 INT78296 Negative_regulation of Binding of Ptpra and Ldlr 1 0.22 0.25 0.24
6 INT78293 Binding of Apoe and Ldlr 1 0.20 0.25 0.24
7 INT78292 Negative_regulation of Binding of Apoe and Ldlr 1 0.23 0.25 0.24
8 INT78291 Binding of Ptpra and Ldlr 1 0.20 0.25 0.24
9 INT187486 Binding of Prkag1 and Stk11 1 0.01 0.95 0.22
10 INT96417 CYC1 Positive_regulation of Casp9 1 0.02 0.96 0.17
11 INT96416 CYC1 Positive_regulation of Casp3 1 0.02 0.96 0.17
12 INT293124 Agtr1a Regulation of Gene_expression of Aqp2 1 0.17 0.36 0.14
13 INT293117 Agt Regulation of Gene_expression of Aqp2 1 0.23 0.36 0.14
14 INT351974 Agt Positive_regulation of Gene_expression of Stk11 1 0.51 11.1 0.12
15 INT273103 Binding of Mtor and Rps6kb1 1 0.44 0 0.11
16 INT189559 STK11 Positive_regulation of SNRK 1 0.03 0.36 0.11
17 INT273112 Positive_regulation of Binding of Mtor and Rps6kb1 1 0.46 0.05 0.11
18 INT234802 Binding of AQP2 and AVPR2 2 0.15 0.84 0.07
19 INT71344 Ldlr Positive_regulation of Hdlcl1 1 0.01 0.69 0.06
20 INT66590 Gnrhr Regulation of Ldlr 1 0.02 0.4 0.06
21 INT71343 Negative_regulation of Ldlr Positive_regulation of Hdlcl1 1 0.01 0.69 0.06
22 INT313886 RPS6KB1 Positive_regulation of Gene_expression of XRCC1 1 0.01 0.8 0.05
23 INT293122 Avp Regulation of Gene_expression of Aqp2 1 0.04 0.81 0.05
24 INT150048 Ins1 Positive_regulation of Rps6kb1 2 0.23 0.83 0.04
25 INT257869 Rps6kb1 Regulation of Eif4ebp1 1 0.02 0.64 0.04
26 INT257872 Eif4ebp1 Regulation of Rps6kb1 1 0.02 0.64 0.04
27 INT228679 Binding of Rps6kb1 and Fig4 1 0.08 0.08 0.04
28 INT257868 Agt Positive_regulation of Rps6kb1 1 0.10 0.37 0.04
29 INT273117 Trh Positive_regulation of Rps6kb1 1 0.01 0.09 0.04
30 INT253375 Lep Positive_regulation of Phosphorylation of Rps6kb1 1 0.41 0.16 0.03
31 INT253412 ATIC Negative_regulation of Rps6kb1 1 0.02 0 0.03
32 INT241775 AVP Positive_regulation of Gene_expression of AQP2 1 0.08 0.17 0
33 INT351972 Binding of Agt and Stk11 1 0.27 0.74 0
34 INT280619 Ins1 Positive_regulation of Srebf1 1 0.04 0.16 0
35 INT284311 RPS6KB1 Positive_regulation of Phosphorylation of IRS1 1 0.18 0.24 0
36 INT188067 Rps6kb1 Regulation of Rps6 1 0.10 0.1 0
37 INT351975 Agt Positive_regulation of Stk11 1 0.34 0.39 0
38 INT351984 Gene_expression of Stk11 Positive_regulation of Gene_expression of Dcc 1 0.01 1.8 0
39 INT221256 Negative_regulation of CYC1 Positive_regulation of Gene_expression of Ros1 1 0.07 0.96 0
40 INT351982 Smarca4 Positive_regulation of Stk11 1 0.05 0.58 0
41 INT317842 Hdlcl1 Positive_regulation of Ldlr 1 0.00 1.11 0
42 INT253380 Il6 Positive_regulation of Phosphorylation of Rps6kb1 1 0.29 0.07 0
43 INT253364 Lep Positive_regulation of Rps6kb1 1 0.30 0.08 0
44 INT345486 PMAIP1 Positive_regulation of Localization of CYC1 1 0.18 0.96 0
45 INT351985 Stk11 Positive_regulation of Gene_expression of Dcc 1 0.01 1.79 0
46 INT293114 Fig4 Regulation of Gene_expression of Aqp2 1 0.08 1.53 0
47 INT289519 Sirt1 Regulation of Rps6kb1 1 0.25 0.13 0
48 INT351976 Binding of Tp53 and Stk11 1 0.13 2.3 0
49 INT234803 AVP Regulation of AQP2 1 0.11 1.3 0
50 INT259094 STK11 Positive_regulation of Gene_expression of TCEAL1 1 0.18 5.5 0
51 INT234796 Binding of AQP2 and AVP 1 0.15 1.1 0
52 INT351095 Binding of FKBP1A and RPS6KB1 1 0.24 0.36 0
53 INT351101 Negative_regulation of Binding of FKBP1A and RPS6KB1 1 0.27 0.36 0
54 INT221252 Akt1 Negative_regulation of Localization of CYC1 1 0.15 0.9 0
55 INT289527 Lep Regulation of Rps6kb1 1 0.10 0.07 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for response to glucagon stimulus. They are ordered first by their pain relevance and then by number of times they were reported in response to glucagon stimulus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5164 Negative_regulation of Ldlr 83 0.58 55.01 7.87
2 INT91509 Localization of CYC1 39 0.78 34.74 7.17
3 INT10863 Positive_regulation of Ldlr 45 0.68 31.06 7.05
4 INT91511 Positive_regulation of Localization of CYC1 15 0.67 14.68 3.57
5 INT122997 Phosphorylation of Rps6kb1 46 0.72 9.92 3.43
6 INT5166 Binding of Ldlr 14 0.48 11.95 3.32
7 INT10057 Gene_expression of Ldlr 35 0.67 23.99 3.05
8 INT228677 Negative_regulation of Phosphorylation of Rps6kb1 24 0.51 3.88 2.97
9 INT19335 Positive_regulation of CYC1 11 0.67 9.82 2.92
10 INT84599 Gene_expression of Aqp2 31 0.77 22.58 2.54
11 INT84595 Negative_regulation of Aqp2 11 0.58 4.88 1.78
12 INT122468 Negative_regulation of Localization of CYC1 8 0.57 7.75 1.74
13 INT91508 Positive_regulation of Gene_expression of CYC1 5 0.49 3.76 1.46
14 INT91506 Gene_expression of CYC1 6 0.65 2.7 1.37
15 INT10829 Regulation of Ldlr 12 0.34 8.12 1.35
16 INT33520 Negative_regulation of CYC1 11 0.57 5.36 1.26
17 INT228670 Negative_regulation of Rps6kb1 12 0.38 5.27 1.21
18 INT100328 Gene_expression of AQP2 6 0.75 2.41 1.21
19 INT79557 Localization of Aqp2 5 0.73 2 1.13
20 INT84597 Transcription of Aqp2 3 0.55 2.11 0.98
21 INT84598 Regulation of Aqp2 13 0.45 4.28 0.86
22 INT108348 Positive_regulation of Aqp2 10 0.68 4.94 0.82
23 INT174069 Positive_regulation of Rps6kb1 14 0.61 3.7 0.77
24 INT149238 Positive_regulation of Gene_expression of Aqp2 5 0.66 3.07 0.73
25 INT122999 Gene_expression of Rps6kb1 16 0.67 3.45 0.71
26 INT241788 Positive_regulation of Gene_expression of AQP2 3 0.67 1.26 0.7
27 INT112465 Binding of Rps6kb1 3 0.25 1.26 0.69
28 INT84596 Negative_regulation of Gene_expression of Aqp2 3 0.58 8.49 0.6
29 INT200090 Positive_regulation of Gene_expression of Ldlr 5 0.37 3.67 0.59
30 INT84594 Negative_regulation of Transcription of Aqp2 1 0.43 0 0.59
31 INT100322 Localization of AQP2 5 0.80 0.56 0.56
32 INT263820 Phosphorylation of RPS6KB1 6 0.52 1.43 0.42
33 INT149235 Positive_regulation of Transcription of Aqp2 1 0.45 0.72 0.4
34 INT149244 Positive_regulation of Localization of Aqp2 1 0.49 0.72 0.4
35 INT106255 Positive_regulation of Positive_regulation of CYC1 2 0.49 2.18 0.39
36 INT138380 Regulation of Transcription of Ldlr 1 0.38 0.21 0.38
37 INT100324 Regulation of Localization of AQP2 1 0.27 0.19 0.38
38 INT138379 Transcription of Ldlr 1 0.59 0.21 0.38
39 INT157836 Regulation of Gene_expression of Aqp2 9 0.57 8.37 0.37
40 INT90876 Negative_regulation of RPS6KB1 2 0.47 1.29 0.36
41 INT100323 Regulation of Gene_expression of AQP2 1 0.45 0.18 0.36
42 INT5168 Regulation of Binding of Ldlr 1 0.45 0 0.36
43 INT351970 Gene_expression of Stk11 1 0.75 33.89 0.35
44 INT122996 Positive_regulation of Phosphorylation of Rps6kb1 9 0.58 1.53 0.34
45 INT79558 Binding of Aqp2 2 0.31 0.25 0.33
46 INT281599 Localization of Rps6kb1 2 0.59 0.61 0.28
47 INT33521 Negative_regulation of Negative_regulation of CYC1 4 0.41 1.75 0.24
48 INT37790 Localization of Ldlr 5 0.38 2.29 0.23
49 INT281588 Negative_regulation of Localization of Rps6kb1 2 0.33 0.16 0.22
50 INT270722 Regulation of Positive_regulation of RPS6KB1 2 0.49 1.07 0.19
51 INT351969 Positive_regulation of Gene_expression of Stk11 1 0.67 21.03 0.19
52 INT5165 Positive_regulation of Binding of Ldlr 1 0.50 0 0.19
53 INT228901 Positive_regulation of RPS6KB1 5 0.55 2.44 0.18
54 INT5167 Negative_regulation of Binding of Ldlr 1 0.43 0 0.17
55 INT280689 Regulation of Srebf1 1 0.29 0.42 0.17
56 INT196603 Gene_expression of STK11 5 0.55 6.75 0.15
57 INT189633 Regulation of STK11 3 0.41 3.57 0.14
58 INT257862 Negative_regulation of Positive_regulation of Rps6kb1 3 0.38 1.24 0.13
59 INT106227 Binding of STK11 3 0.42 3.13 0.13
60 INT189583 Transcription of STK11 2 0.49 4.43 0.13
61 INT330233 Positive_regulation of Stk11 2 0.67 8.15 0.13
62 INT105085 Binding of CYC1 2 0.36 2.11 0.12
63 INT215136 Regulation of Gene_expression of Ldlr 2 0.12 0.76 0.12
64 INT116739 Protein_catabolism of Ldlr 1 0.87 1.18 0.12
65 INT46335 Regulation of Rps6kb1 8 0.40 2.39 0.11
66 INT228902 Gene_expression of RPS6KB1 5 0.75 2.32 0.1
67 INT34582 Negative_regulation of Positive_regulation of Ldlr 2 0.03 1.33 0.1
68 INT349555 Positive_regulation of Localization of Rps6kb1 1 0.39 0.45 0.09
69 INT167019 Negative_regulation of Gene_expression of Ldlr 3 0.42 0.76 0.08
70 INT122998 Positive_regulation of Gene_expression of Rps6kb1 2 0.60 0.62 0.08
71 INT157832 Phosphorylation of Aqp2 2 0.77 2.04 0.08
72 INT284331 Positive_regulation of Phosphorylation of RPS6KB1 5 0.32 0.7 0.05
73 INT293110 Positive_regulation of Phosphorylation of Aqp2 1 0.47 1.39 0.05
74 INT263818 Negative_regulation of Phosphorylation of RPS6KB1 1 0.01 0.43 0.05
75 INT330228 Phosphorylation of Stk11 1 0.18 0.27 0.05
76 INT330227 Positive_regulation of Positive_regulation of Stk11 1 0.11 0.06 0.05
77 INT348079 Negative_regulation of Negative_regulation of Ldlr 1 0.12 1.03 0.05
78 INT351967 Negative_regulation of Gene_expression of Stk11 1 0.57 0.89 0.04
79 INT351966 Binding of Stk11 1 0.36 2.15 0.04
80 INT280684 Transcription of Srebf1 11 0.50 2.38 0.03
81 INT297432 Positive_regulation of Localization of Ldlr 2 0.14 0.35 0.03
82 INT293105 Positive_regulation of Positive_regulation of Aqp2 1 0.47 0.72 0.03
83 INT241787 Negative_regulation of AQP2 1 0.57 1.38 0.03
84 INT257851 Regulation of Phosphorylation of Rps6kb1 1 0.40 0.95 0.03
85 INT280683 Gene_expression of Srebf1 12 0.44 6.31 0
86 INT280659 Negative_regulation of Srebf1 4 0.32 1.83 0
87 INT280643 Negative_regulation of Gene_expression of Srebf1 4 0.32 1.01 0
88 INT280638 Positive_regulation of Transcription of Srebf1 4 0.37 1.18 0
89 INT280673 Positive_regulation of Srebf1 3 0.37 0.96 0
90 INT280636 Negative_regulation of Transcription of Srebf1 3 0.31 0.71 0
91 INT228900 Positive_regulation of Gene_expression of RPS6KB1 2 0.49 1.6 0
92 INT280649 Positive_regulation of Positive_regulation of Srebf1 2 0.37 0.64 0
93 INT259109 Negative_regulation of STK11 2 0.54 2.11 0
94 INT280662 Negative_regulation of Positive_regulation of Srebf1 2 0.31 0.65 0
95 INT345450 Binding of Srebf1 1 0.03 0 0
96 INT234743 Regulation of Negative_regulation of CYC1 1 0.01 1.01 0
97 INT351115 Negative_regulation of Binding of RPS6KB1 1 0.34 0.29 0
98 INT234747 Negative_regulation of Regulation of CYC1 1 0.01 1.01 0
99 INT289570 Positive_regulation of Regulation of Rps6kb1 1 0.24 0.06 0
100 INT351117 Binding of RPS6KB1 1 0.30 0.77 0
101 INT157833 Negative_regulation of Negative_regulation of Aqp2 1 0.36 0 0
102 INT108349 Regulation of AQP2 1 0.44 0 0
103 INT100325 Positive_regulation of AQP2 1 0.69 0 0
104 INT253407 Negative_regulation of Gene_expression of Rps6kb1 1 0.29 0 0
105 INT351968 Negative_regulation of Stk11 1 0.42 4.84 0
106 INT341042 Positive_regulation of Protein_catabolism of Aqp2 1 0.34 0.07 0
107 INT351971 Regulation of Stk11 1 0.26 0.43 0
108 INT351129 Regulation of RPS6KB1 1 0.36 0.15 0
109 INT100326 Positive_regulation of Localization of AQP2 1 0.69 0 0
110 INT304206 Positive_regulation of Gene_expression of Srebf1 1 0.34 0.61 0
111 INT280640 Regulation of Transcription of Srebf1 1 0.21 0.09 0
112 INT234749 Regulation of CYC1 1 0.01 0.5 0
113 INT341039 Protein_catabolism of Aqp2 1 0.47 0.06 0
114 INT284330 Positive_regulation of Positive_regulation of RPS6KB1 1 0.23 0.24 0
115 INT242091 Phosphorylation of STK11 1 0.30 1.93 0
116 INT280669 Localization of Srebf1 1 0.35 0.09 0
117 INT100327 Regulation of Positive_regulation of AQP2 1 0.39 0 0
118 INT257856 Positive_regulation of Positive_regulation of Rps6kb1 1 0.61 0.64 0
119 INT280687 Protein_catabolism of Srebf1 1 0.41 0 0
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