GO:0034154

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Name toll-like receptor 7 signaling pathway
Categary Process
Go Slim No
Go Link GO:0034154
Unique Molecular Interactions 15
Total Molecular Interactions 16
Total Single Events 110
Pain Genes Associated 4

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for toll-like receptor 7 signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported for toll-like receptor 7 signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT178218 IFNA1 Regulation of Tlr7 1 0.04 0.87 0.37
2 INT137160 TLR7 Positive_regulation of Gene_expression of CXCR3 1 0.35 0.34 0.32
3 INT137159 Binding of TLR7 and TLR9 1 0.27 0.33 0.29
4 INT137169 Binding of TLR5 and TLR7 1 0.25 0.33 0.29
5 INT288497 Binding of Tlr7 and Tlr9 1 0.21 0.97 0.27
6 INT260437 Positive_regulation of Tlr7 Positive_regulation of Positive_regulation of Il12a 1 0.03 0.27 0.21
7 INT260441 Negative_regulation of Tlr7 Negative_regulation of Positive_regulation of IFNA1 1 0.05 0.96 0.21
8 INT260436 Positive_regulation of Tlr9 Negative_regulation of Positive_regulation of Tlr7 1 0.14 0.65 0.2
9 INT345280 Binding of Tlr2 and Tlr7 1 0.05 0.49 0.12
10 INT329045 Binding of Unc93b1 and Tlr3 1 0.03 0.7 0.05
11 INT260435 Binding of Tlr9 and Tlr7 1 0.09 0.71 0.05
12 INT334262 Myd88 Positive_regulation of Tlr7 1 0.05 0.3 0.04
13 INT290313 Binding of MYD88 and TLR7 1 0.03 0.1 0.03

Single Events

The table below shows the top 100 pain related interactions that have been reported for toll-like receptor 7 signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported in toll-like receptor 7 signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT219180 Gene_expression of TLR7 13 0.68 9.51 2.21
2 INT188678 Binding of Tlr7 14 0.32 6.6 1.89
3 INT178188 Positive_regulation of Tlr7 12 0.40 6.33 1.77
4 INT174689 Gene_expression of Tlr7 11 0.67 8.24 1.56
5 INT219159 Positive_regulation of TLR7 8 0.55 2.37 1.32
6 INT120599 Binding of Tlr7 2 0.27 2.16 0.96
7 INT280014 Binding of TLR7 4 0.14 3.52 0.76
8 INT288495 Gene_expression of Tlr7 3 0.50 2.83 0.76
9 INT178202 Regulation of Tlr7 2 0.34 1.69 0.59
10 INT260425 Positive_regulation of Gene_expression of Tlr7 3 0.39 2.88 0.53
11 INT285448 Positive_regulation of Gene_expression of TLR7 4 0.61 2.58 0.5
12 INT245223 Negative_regulation of Gene_expression of TLR7 3 0.37 2.81 0.5
13 INT260427 Negative_regulation of Tlr7 2 0.33 1.42 0.42
14 INT178171 Localization of Tlr7 1 0.51 0.53 0.41
15 INT219182 Negative_regulation of Positive_regulation of TLR7 1 0.24 1.3 0.39
16 INT219175 Localization of TLR7 2 0.49 1.32 0.25
17 INT245222 Regulation of TLR7 2 0.39 1.52 0.19
18 INT120600 Positive_regulation of Binding of Tlr7 1 0.04 0.17 0.12
19 INT260428 Regulation of Gene_expression of Tlr7 1 0.25 1.01 0.12
20 INT188681 Positive_regulation of Binding of Tlr7 1 0.17 0 0.11
21 INT280012 Positive_regulation of Binding of TLR7 1 0.18 1.11 0.09
22 INT322026 Positive_regulation of Positive_regulation of TLR7 1 0.40 0.06 0.08
23 INT288492 Negative_regulation of Gene_expression of Tlr7 1 0.32 0.63 0.04
24 INT329052 Gene_expression of Unc93b1 1 0.04 0.74 0.04
25 INT324758 Negative_regulation of Positive_regulation of Tlr7 1 0.21 0.22 0.03
26 INT110559 Positive_regulation of Tlr7 1 0.04 0.19 0
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