GO:0034186

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Name apolipoprotein A-I binding
Categary Function
Go Slim No
Go Link GO:0034186
Unique Molecular Interactions 87
Total Molecular Interactions 110
Total Single Events 577
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for apolipoprotein A-I binding. They are ordered first by their pain relevance and then by number of times they were reported for apolipoprotein A-I binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT284481 Binding of ABCA1 and Ighg1 1 0.00 1.39 0.7
2 INT125699 CR1 Negative_regulation of Positive_regulation of ABCA1 1 0.03 0.64 0.53
3 INT345308 Binding of ABCA1 and TIMP2 1 0.00 0.21 0.52
4 INT187114 TIMP2 Negative_regulation of ABCA1 1 0.02 0.28 0.51
5 INT187108 TIMP1 Negative_regulation of ABCA1 1 0.02 0.28 0.51
6 INT193480 Binding of ABCA1 and IRF6 1 0.00 1.08 0.46
7 INT136749 COX5A Positive_regulation of Gene_expression of SCARB1 1 0.52 0.36 0.45
8 INT307781 Apoa1 Positive_regulation of LCAT 1 0.76 1.19 0.45
9 INT213027 Binding of Apoa1 and Scarb1 6 0.09 7.52 0.43
10 INT122049 Binding of HSD11B1 and Lcat 1 0.21 0.83 0.31
11 INT213029 Positive_regulation of Binding of Apoa1 and Scarb1 1 0.09 3.38 0.27
12 INT186191 Binding of SCARB1 and TBP 1 0.03 2.57 0.24
13 INT239337 Abca1 Positive_regulation of RCT 1 0.07 3.11 0.24
14 INT239316 Nr1h2 Positive_regulation of Transcription of Abca1 1 0.15 0.67 0.18
15 INT335046 PPARA Positive_regulation of Gene_expression of ABCA1 1 0.33 0.25 0.18
16 INT47344 CPZ Negative_regulation of LCAT 1 0.29 0 0.18
17 INT207345 PTGDS Negative_regulation of Gene_expression of ABCA1 1 0.21 0 0.17
18 INT207359 ZNF398 Negative_regulation of ABCA1 1 0.01 0 0.17
19 INT208360 Binding of Abca1 and Apoe 1 0.15 0.74 0.17
20 INT207344 PTGER2 Negative_regulation of Gene_expression of ABCA1 1 0.04 0 0.17
21 INT207350 TBXA2R Regulation of Gene_expression of ABCA1 1 0.10 0 0.17
22 INT207338 Negative_regulation of CPOX Negative_regulation of ABCA1 1 0.11 0 0.16
23 INT335459 ABCA1 Positive_regulation of ITPR3 1 0.00 0 0.15
24 INT156531 Binding of ABCA1 and HSD11B1 1 0.22 1.06 0.14
25 INT207360 PTGDS Negative_regulation of Negative_regulation of ABCA1 1 0.25 0 0.14
26 INT344707 Scarb1 Positive_regulation of Positive_regulation of Hdl1 1 0.14 0.88 0.14
27 INT207337 PTGER2 Negative_regulation of Negative_regulation of ABCA1 1 0.04 0 0.14
28 INT207353 ZNF398 Regulation of ABCA1 1 0.00 0 0.14
29 INT344705 Nr1h2 Regulation of Scarb1 1 0.04 1.53 0.12
30 INT344706 Nr1h2 Regulation of Abca1 1 0.03 2.39 0.12
31 INT293236 IDO1 Regulation of ABCA1 1 0.00 0 0.11
32 INT42224 ABCA1 Positive_regulation of CYBB 1 0.01 0 0.09
33 INT42225 Binding of ABCA1 and DECR1 1 0.02 0 0.08
34 INT289258 Binding of ABCA1 and Il6ra 1 0.00 0.33 0.07
35 INT239346 Olfr642 Positive_regulation of Lcat 1 0.00 1.06 0.07
36 INT262175 Nr1i2 Positive_regulation of Gene_expression of Abca1 1 0.24 0.21 0.06
37 INT239327 Positive_regulation of Binding of Lcat and Hdl1 1 0.06 1.52 0.06
38 INT239331 RCT Positive_regulation of Lcat 1 0.08 1.08 0.06
39 INT239354 CETP Positive_regulation of Lcat 1 0.28 1.09 0.06
40 INT239326 Binding of Lcat and Hdl1 1 0.05 1.52 0.06
41 INT293233 IDO1 Positive_regulation of ABCA1 1 0.01 0 0.06
42 INT186188 Binding of SCARB1 and PDZK1 1 0.53 0.54 0.05
43 INT339583 Binding of ABCA1 and RPE 1 0.03 1.38 0.05
44 INT339587 Positive_regulation of Binding of ABCA1 and RPE 1 0.04 1.38 0.05
45 INT188432 Negative_regulation of Binding of ABCA1 and IL6 1 0.02 0.47 0.05
46 INT186185 Binding of SCARB1 and SCARB2 1 0.22 0.58 0.05
47 INT188431 Binding of ABCA1 and IL6 1 0.02 0.47 0.05
48 INT186187 LDLR Regulation of Gene_expression of SCARB1 1 0.17 1.71 0.04
49 INT290375 Binding of Scarb1 and Gopc 1 0.15 0.29 0.04
50 INT213002 Binding of Scarb1 and Trib3 1 0.00 1.02 0.03
51 INT213011 Binding of Scarb1 and Hdl1 1 0.13 0.96 0.03
52 INT230136 OSBPL8 Regulation of Binding of ABCA1 1 0.07 0.17 0.03
53 INT186186 LDLR Regulation of SCARB1 1 0.08 0.65 0.03
54 INT207343 Negative_regulation of CPOX Negative_regulation of Gene_expression of ABCA1 1 0.09 0 0.03
55 INT247155 Binding of Phb2 and Scarb1 1 0.01 0.33 0
56 INT284392 Binding of ABCA1 and Vegfa 1 0.00 0.71 0
57 INT229927 CD59 Negative_regulation of Binding of ABCA1 1 0.01 0 0
58 INT186190 OLR1 Positive_regulation of SCARB1 1 0.01 0.67 0
59 INT229923 Binding of ABCA1 and C9 1 0.00 0.74 0
60 INT326065 APOE Positive_regulation of LCAT 1 0.53 0.84 0
61 INT284372 Binding of ABCA1 and AMT 1 0.00 0 0
62 INT260519 Binding of Prnp and Scarb1 1 0.41 0.21 0
63 INT290374 Binding of Scarb1 and Ncapg2 1 0.23 0.43 0
64 INT326061 Binding of HSD11B1 and LCAT 1 0.11 0.89 0
65 INT239341 Binding of Abca1 and Hdl1 1 0.04 4.78 0
66 INT260520 Binding of Myc and Scarb1 1 0.33 0.16 0
67 INT297056 Binding of ABCA1 and Oas1b 1 0.00 0.13 0
68 INT117795 ABCA1 Regulation of GHRL 1 0.00 0 0
69 INT284393 Positive_regulation of Binding of ABCA1 and Vegfa 1 0.00 0.36 0
70 INT326085 Prkaca Regulation of Phosphorylation of ABCA1 1 0.02 0.44 0
71 INT229981 Binding of ABCA1 and Cdca3 1 0.00 0.74 0
72 INT186189 LDLR Positive_regulation of Gene_expression of SCARB1 1 0.14 1.27 0
73 INT239342 Lcat Regulation of Apoa1 1 0.16 0.65 0
74 INT290373 Binding of Cd36 and Scarb1 1 0.11 0 0
75 INT144760 Binding of ABCA1 and Insr 1 0.00 0 0
76 INT339580 TIMP3 Positive_regulation of ABCA1 1 0.16 0.73 0
77 INT326060 Binding of ABCA1 and APOA1 1 0.39 1.5 0
78 INT307283 Binding of ABCA1 and PMP2 1 0.00 0 0
79 INT326084 Prkaca Positive_regulation of Phosphorylation of ABCA1 1 0.06 0.44 0
80 INT217396 Binding of Abca1 and App 1 0.26 0.83 0
81 INT213043 Regulation of Binding of Apoa1 and Scarb1 1 0.05 1.12 0
82 INT344712 Nr1h3 Regulation of Abca1 1 0.03 1.68 0
83 INT239321 Binding of Abca1 and Apoa1 1 0.11 1.61 0
84 INT290372 Binding of Ngfr and Scarb1 1 0.01 0.48 0
85 INT304270 Binding of Apoa1 and Scarb1 1 0.00 0.39 0
86 INT295499 Lcat Regulation of Transcription of Hmgcr 1 0.04 0.2 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for apolipoprotein A-I binding. They are ordered first by their pain relevance and then by number of times they were reported in apolipoprotein A-I binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT36453 Binding of ABCA1 48 0.45 19.9 10.84
2 INT28312 Gene_expression of ABCA1 85 0.72 37.69 9.27
3 INT136754 Gene_expression of SCARB1 64 0.77 43.28 4.82
4 INT2848 Localization of ABCA1 23 0.70 10.64 4.73
5 INT18670 Negative_regulation of ABCA1 16 0.54 5.8 3.39
6 INT28130 Positive_regulation of ABCA1 18 0.61 7.08 3.22
7 INT44873 Negative_regulation of LCAT 16 0.59 6.92 3.13
8 INT190081 Gene_expression of Abca1 21 0.65 18.18 2.45
9 INT207370 Negative_regulation of Gene_expression of ABCA1 1 0.54 2.75 1.78
10 INT136752 Positive_regulation of Gene_expression of SCARB1 5 0.69 10.63 1.76
11 INT239302 Positive_regulation of Gene_expression of Abca1 9 0.32 9.1 1.06
12 INT21546 Regulation of ABCA1 16 0.40 4.21 1.04
13 INT44874 Regulation of LCAT 1 0.62 0.15 1
14 INT211557 Gene_expression of Scarb1 30 0.75 5.03 0.94
15 INT294479 Gene_expression of Scarb1 1 0.02 3.08 0.9
16 INT190089 Binding of Abca1 5 0.36 2.21 0.83
17 INT136753 Regulation of Gene_expression of SCARB1 2 0.60 7.79 0.77
18 INT136751 Negative_regulation of SCARB1 6 0.43 2.65 0.7
19 INT164627 Positive_regulation of Gene_expression of ABCA1 9 0.61 3.95 0.67
20 INT136755 Negative_regulation of Gene_expression of SCARB1 2 0.57 6.61 0.63
21 INT212959 Binding of Scarb1 12 0.35 7.7 0.61
22 INT277710 Regulation of Localization of ABCA1 1 0.04 1.73 0.56
23 INT136757 Regulation of SCARB1 4 0.27 1.96 0.48
24 INT167468 Regulation of Gene_expression of ABCA1 5 0.52 0.08 0.43
25 INT122047 Positive_regulation of Lcat 3 0.35 1.94 0.4
26 INT209180 Transcription of ABCA1 4 0.47 1.09 0.39
27 INT345322 Regulation of Transcription of ABCA1 1 0.01 0 0.39
28 INT167122 Protein_catabolism of ABCA1 3 0.02 0.27 0.37
29 INT16855 Binding of Scarb1 1 0.21 0 0.33
30 INT16856 Positive_regulation of Binding of Scarb1 1 0.27 0 0.33
31 INT239295 Positive_regulation of Abca1 3 0.30 2.18 0.32
32 INT344673 Positive_regulation of Binding of Scarb1 1 0.16 0.82 0.28
33 INT239279 Regulation of Gene_expression of Abca1 2 0.44 2.42 0.26
34 INT344685 Positive_regulation of Binding of Abca1 1 0.12 0.76 0.26
35 INT284385 Positive_regulation of Localization of ABCA1 2 0.02 0.22 0.25
36 INT307183 Positive_regulation of Gene_expression of Scarb1 1 0.07 0.93 0.22
37 INT175691 Gene_expression of Lcat 6 0.57 7.87 0.21
38 INT186199 Binding of SCARB1 3 0.37 5.25 0.21
39 INT239287 Transcription of Abca1 1 0.32 1.87 0.21
40 INT300227 Positive_regulation of Binding of ABCA1 1 0.41 1.85 0.19
41 INT277709 Regulation of Binding of ABCA1 1 0.04 0.52 0.19
42 INT239308 Positive_regulation of Transcription of Abca1 1 0.28 0.67 0.18
43 INT290336 Negative_regulation of Scarb1 4 0.31 1.77 0.17
44 INT211552 Localization of Scarb1 3 0.60 1.27 0.17
45 INT217387 Regulation of Abca1 3 0.27 2.01 0.15
46 INT59956 Positive_regulation of SCARB1 3 0.49 0.99 0.12
47 INT3442 Negative_regulation of Lcat 2 0.42 4.36 0.12
48 INT239288 Binding of Lcat 1 0.27 2.59 0.12
49 INT42227 Negative_regulation of Positive_regulation of ABCA1 1 0.03 0 0.09
50 INT42226 Positive_regulation of Positive_regulation of ABCA1 1 0.02 0 0.09
51 INT262061 Negative_regulation of Gene_expression of Abca1 1 0.19 0.68 0.08
52 INT239277 Positive_regulation of Binding of Lcat 1 0.37 1.09 0.06
53 INT239298 Regulation of Lcat 1 0.33 1.96 0.06
54 INT239296 Negative_regulation of Abca1 3 0.26 3.83 0.04
55 INT290345 Negative_regulation of Gene_expression of Scarb1 1 0.42 0.5 0.04
56 INT253595 Localization of Abca1 2 0.37 0.35 0.03
57 INT290334 Negative_regulation of Binding of Scarb1 1 0.31 0.12 0.03
58 INT187415 Gene_expression of LCAT 3 0.39 1.26 0
59 INT326077 Positive_regulation of Transcription of ABCA1 1 0.41 0.22 0
60 INT326076 Phosphorylation of ABCA1 1 0.73 0.66 0
61 INT239274 Negative_regulation of Gene_expression of Lcat 1 0.43 1.6 0
62 INT273148 Localization of LCAT 1 0.38 0.91 0
63 INT312779 Gene_expression of Lcat 1 0.37 0.82 0
64 INT312790 Regulation of Gene_expression of Lcat 1 0.21 0.88 0
65 INT273152 Positive_regulation of Localization of LCAT 1 0.26 0.91 0
66 INT186198 Positive_regulation of Transcription of SCARB1 1 0.49 0.67 0
67 INT326083 Positive_regulation of Phosphorylation of ABCA1 1 0.61 0.66 0
68 INT312775 Positive_regulation of Lcat 1 0.19 0.91 0
69 INT290350 Transcription of Scarb1 1 0.50 0.24 0
70 INT295508 Transcription of Lcat 1 0.08 0.2 0
71 INT175683 Negative_regulation of Lcat 1 0.21 2.28 0
72 INT290341 Positive_regulation of Negative_regulation of Scarb1 1 0.32 0.69 0
73 INT312791 Regulation of Lcat 1 0.13 0.83 0
74 INT300233 Positive_regulation of Gene_expression of LCAT 1 0.29 0.98 0
75 INT212958 Positive_regulation of Scarb1 1 0.20 1.29 0
76 INT213135 Negative_regulation of Scarb1 1 0.02 2.06 0
77 INT186195 Transcription of SCARB1 1 0.70 1.42 0
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