GO:0034220

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Name ion transmembrane transport
Categary Process
Go Slim No
Go Link GO:0034220
Unique Molecular Interactions 1444
Total Molecular Interactions 1979
Total Single Events 22965
Pain Genes Associated 93

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for ion transmembrane transport. They are ordered first by their pain relevance and then by number of times they were reported for ion transmembrane transport. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT106676 Binding of Trpv1 and Phax 18 0.34 4.19 12.36
2 INT145775 Ngf Positive_regulation of Trpv1 11 0.72 7.71 11.25
3 INT251170 Clu Positive_regulation of Trpv1 1 0.28 2.61 6.49
4 INT122779 Ngf Positive_regulation of Gene_expression of Trpv1 8 0.74 4.31 6.1
5 INT351352 Binding of Trpv1 and Lpar1 1 0.21 5.86 4.62
6 INT296484 Binding of Gria2 and GRIP1 1 0.04 4.52 4.59
7 INT180774 Gdnf Positive_regulation of Trpv1 1 0.33 2.43 4.37
8 INT122349 Ngf Regulation of Trpv1 3 0.64 1.55 3.79
9 INT136525 Binding of Prokr1 and Trpv1 1 0.39 2.9 3.76
10 INT141254 Ngf Regulation of Transcription of Trpv1 1 0.53 1.37 3.74
11 INT158770 Binding of Trpv1 and Trpa1 5 0.34 2.07 3.5
12 INT195931 Binding of OPRM1 and Trpv1 1 0.07 0.87 3.43
13 INT354207 Igfbp7 Positive_regulation of Accn3 1 0.52 6.55 3.24
14 INT146412 Tnf Positive_regulation of Gene_expression of Trpv1 2 0.66 5.22 3.22
15 INT251146 Binding of Grin1 and Dlg2 1 0.36 1.95 3.16
16 INT122780 Ngf Regulation of Gene_expression of Trpv1 4 0.65 3.74 3.11
17 INT101408 Binding of Grin1 and Olr1469 1 0.03 0.86 3.1
18 INT101407 Binding of Grin1 and Spr 1 0.14 0.86 3.09
19 INT122776 Gdnf Positive_regulation of Gene_expression of Trpv1 2 0.67 2.13 3.06
20 INT102284 Binding of Grin1 and Grin2a 5 0.27 1.79 3.01
21 INT156381 Binding of Grin1 and Dlg4 1 0.39 0.86 2.9
22 INT170367 Binding of Grin1 and Grin2a 5 0.23 1.72 2.79
23 INT169134 Binding of Calca and Trpa1 1 0.37 3.37 2.79
24 INT140347 Binding of ATP1A2 and Cacna1a 1 0.11 2.88 2.73
25 INT182564 Binding of Ptger2 and Trpv1 1 0.18 1.77 2.67
26 INT351444 Grin1 Positive_regulation of Gria2 1 0.22 1.5 2.64
27 INT210696 Trpv1 Regulation of Slc12a2 1 0.25 1.97 2.58
28 INT317528 Ppp1r9b Regulation of Grin1 1 0.18 0.2 2.48
29 INT251147 Binding of Grin2b and Dlg2 1 0.33 2.75 2.43
30 INT122775 Gdnf Regulation of Gene_expression of Trpv1 4 0.59 2.72 2.42
31 INT107578 Kitl Negative_regulation of Grin2b 1 0.12 2.05 2.36
32 INT107165 Binding of Gabrg1 and Trpv1 2 0.01 0.16 2.34
33 INT228454 Ngf Positive_regulation of Phosphorylation of Trpv1 1 0.39 2.97 2.26
34 INT251164 Binding of Clu and Trpv1 1 0.19 0.44 2.23
35 INT317524 Binding of Camk2a and Grin1 1 0.17 0.06 2.21
36 INT140659 Phax Positive_regulation of Trpv1 3 0.49 0.68 2.18
37 INT251145 Binding of Grin2a and Dlg2 1 0.31 2.3 2.11
38 INT167530 Phax Regulation of Gene_expression of Trpv1 1 0.16 0.86 2.05
39 INT156509 Il6 Regulation of Positive_regulation of Grin1 1 0.28 1.93 1.93
40 INT283050 Binding of Gad2 and Trpm8 1 0.23 2.02 1.93
41 INT120723 Positive_regulation of Trpv1 Positive_regulation of Localization of Calca 3 0.51 0.48 1.92
42 INT262558 Phax Positive_regulation of Trpv1 1 0.01 1.26 1.92
43 INT93293 Ngf Regulation of Trpv1 2 0.28 0.71 1.9
44 INT161079 Mcs18 Negative_regulation of Trpv1 1 0.40 0.82 1.9
45 INT166945 Ngf Positive_regulation of Trpv1 1 0.01 0.47 1.88
46 INT338691 Binding of Trpv1 and Aff3 1 0.24 1.21 1.88
47 INT168723 Positive_regulation of Trpv1 Positive_regulation of Gene_expression of Calca 1 0.48 1.1 1.84
48 INT120732 Prkcg Positive_regulation of Phosphorylation of Grin1 2 0.48 1.04 1.81
49 INT272616 Positive_regulation of Binding of Grin1 and Grin2a 2 0.30 1.36 1.8
50 INT23392 Gal Regulation of Trpv1 1 0.05 0.33 1.77
51 INT276863 Gpr65 Regulation of Trpv1 1 0.25 1.78 1.75
52 INT332773 Positive_regulation of Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.04 0.73 1.75
53 INT165183 Ifnb1 Positive_regulation of P2rx4 1 0.04 1.73 1.73
54 INT182565 Ptger2 Regulation of Trpv1 1 0.25 1.34 1.73
55 INT139156 Binding of Gria1 and Gria2 1 0.23 0.64 1.72
56 INT354210 Binding of Igfbp7 and Accn3 1 0.27 3.91 1.64
57 INT276670 Binding of Trpv1 and Nkx1-1 1 0.07 0.68 1.6
58 INT136034 Edn1 Regulation of Trpv1 2 0.66 0.39 1.58
59 INT131575 Grin1 Negative_regulation of Positive_regulation of Ephb1 1 0.28 0.31 1.58
60 INT168608 Binding of Grin2b and Mmp9 1 0.22 0.41 1.57
61 INT208980 Binding of Ca2 and Trpv1 4 0.32 0.67 1.55
62 INT148821 Binding of Oprm1 and Grin1 1 0.05 0.24 1.55
63 INT249498 Src Positive_regulation of Phosphorylation of Grin2b 1 0.22 1.11 1.54
64 INT149743 Ean5 Positive_regulation of Gene_expression of P2rx2 1 0.10 1.54 1.5
65 INT322812 Binding of SLC12A1 and MOCOS 1 0.00 1.69 1.49
66 INT42000 Trpv1 Positive_regulation of Cck 1 0.04 0 1.49
67 INT41999 Trpv1 Positive_regulation of Vip 1 0.04 0 1.49
68 INT140329 Grin1 Negative_regulation of Ltp 1 0.04 0.64 1.46
69 INT121226 Ngf Regulation of Gene_expression of Trpv1 2 0.62 0.7 1.44
70 INT180789 Ngf Regulation of Localization of Trpv1 1 0.28 1.22 1.44
71 INT180768 Bdnf Regulation of Localization of Trpv1 1 0.13 1.21 1.43
72 INT180790 Gdnf Regulation of Localization of Trpv1 1 0.15 1.21 1.43
73 INT246519 Positive_regulation of Grin2b Positive_regulation of Positive_regulation of Ltp 1 0.25 0.08 1.42
74 INT154685 Syt17 Positive_regulation of Trpa1 1 0.32 0.71 1.4
75 INT144123 Binding of P2rx6 and Trpv1 1 0.11 0 1.4
76 INT293200 Positive_regulation of Grin1 Positive_regulation of Phosphorylation of Grin2b 1 0.24 0.4 1.39
77 INT138099 Binding of Grin2a and Insrr 1 0.01 0.36 1.39
78 INT262568 Prkaca Regulation of Trpv1 2 0.10 0.65 1.38
79 INT167529 Ppt1 Negative_regulation of Gene_expression of Trpv1 1 0.26 0.49 1.38
80 INT108727 Binding of ATP1A2 and CACNA1A 2 0.34 1.97 1.37
81 INT182558 Binding of Ptgir and Trpv1 1 0.16 1.12 1.37
82 INT276673 Nkx1-1 Regulation of Trpv1 1 0.05 0.16 1.37
83 INT261483 Binding of Ephb1 and Trpv1 1 0.39 1.37 1.37
84 INT326194 Bdnf Regulation of Slc12a5 1 0.05 0.85 1.35
85 INT355248 Ltp Positive_regulation of Localization of Trpv1 1 0.51 0 1.35
86 INT121457 KNG1 Positive_regulation of Trpv1 1 0.16 0.91 1.33
87 INT317519 Grin1 Positive_regulation of Negative_regulation of Oprm1 1 0.14 0 1.31
88 INT242605 Gdnf Positive_regulation of Trpv1 1 0.26 0.17 1.3
89 INT261841 Mastl Positive_regulation of Trpa1 1 0.00 0.82 1.3
90 INT121096 Binding of Calca and Trpv1 3 0.37 1.23 1.29
91 INT208990 Binding of CALM1 and Trpv1 1 0.10 0.07 1.29
92 INT154518 Binding of Ephb6 and Grin2b 1 0.21 0.24 1.28
93 INT125950 Syt17 Regulation of Trpv1 1 0.11 0.43 1.28
94 INT64077 Trpv1 Positive_regulation of Kcnma1 1 0.00 0.37 1.27
95 INT155663 Positive_regulation of P2rx4 Positive_regulation of Localization of Bdnf 1 0.42 0.84 1.25
96 INT251142 Binding of Dlg4 and Grin2a 3 0.30 0.5 1.24
97 INT314198 Mapk14 Positive_regulation of Gene_expression of Trpv1 1 0.48 1.09 1.24
98 INT158545 Binding of Trpc3 and Jph2 1 0.55 0 1.24
99 INT195926 Prkaca Positive_regulation of Trpv1 1 0.10 0.44 1.24
100 INT247924 Slc12a5 Regulation of Gene_expression of Slc12a2 1 0.25 1.43 1.23
101 INT247926 Slc12a5 Regulation of Cl 1 0.01 1.43 1.23
102 INT147033 Positive_regulation of Binding of Sds and Accn3 1 0.13 0.73 1.23
103 INT147032 Binding of Sds and Accn3 1 0.09 0.73 1.22
104 INT142154 Trpv1 Positive_regulation of Gene_expression of Il2 1 0.22 0 1.21
105 INT112105 Negative_regulation of Dlg2 Negative_regulation of Gene_expression of Grin2b 2 0.40 0.89 1.2
106 INT166301 Adrbk1 Positive_regulation of Localization of Trpv1 1 0.45 1.17 1.2
107 INT281077 Binding of Gria2 and Gria3 2 0.24 0.35 1.19
108 INT93294 Ngf Regulation of Transcription of Trpv1 1 0.01 0.36 1.19
109 INT256295 Binding of Creb1 and Grin2b 1 0.11 1.21 1.19
110 INT107579 Kitl Negative_regulation of Grin2a 1 0.10 1.02 1.18
111 INT124435 Gene_expression of Chrna9 Positive_regulation of Phosphorylation of Creb1 1 0.11 0.6 1.17
112 INT93290 Ngf Regulation of Transcription of Trpv1 1 0.02 0.34 1.16
113 INT93289 Ngf Regulation of Trpv1 1 0.05 0.34 1.16
114 INT121725 Binding of Trpv1 and Pik3cb 1 0.35 0.62 1.15
115 INT122267 Prkcg Positive_regulation of Grin2b 1 0.26 0.61 1.14
116 INT160653 Binding of P2rx1 and Ptgfr 1 0.28 0.66 1.14
117 INT317553 Binding of Car2 and Grin1 1 0.07 0 1.14
118 INT123387 Binding of Camk2a and Gria2 1 0.13 0.32 1.14
119 INT197051 Binding of HLA-E and ATP8A1 1 0.00 6.52 1.14
120 INT110669 Binding of Alox5 and Trpv1 1 0.07 0.2 1.13
121 INT121362 Trpv1 Regulation of Localization of Ins1 1 0.51 0.17 1.12
122 INT332776 FSCN1 Positive_regulation of Grin1 1 0.02 0.21 1.12
123 INT182550 Ptger1 Negative_regulation of Trpv1 1 0.35 0.73 1.12
124 INT132683 Bdnf Positive_regulation of Phosphorylation of Grin2a 1 0.00 0.93 1.11
125 INT122268 Binding of Grin2b and Grm5 1 0.40 0.52 1.1
126 INT269191 Binding of Grin1 and Grin3a 2 0.32 1.05 1.09
127 INT269189 Binding of Grin2a and Grin3a 2 0.25 1.05 1.09
128 INT121730 Pik3cb Regulation of Trpv1 1 0.58 0.54 1.09
129 INT305734 Binding of Sort1 and Trpv1 1 0.01 0.5 1.08
130 INT317561 Binding of Grin1 and Oprm1 1 0.14 0.09 1.08
131 INT256294 Binding of Grin2b and Ephb1 1 0.28 1.11 1.08
132 INT296458 Binding of Gria2 and Pick1 3 0.24 1.86 1.07
133 INT269193 Prkcg Regulation of Phosphorylation of Grin2a 1 0.02 0.63 1.06
134 INT269192 Ephb1 Regulation of Phosphorylation of Grin2a 1 0.02 0.63 1.06
135 INT296460 Binding of Gria2 and Myo18a 1 0.01 1.49 1.06
136 INT269198 Prkaca Regulation of Phosphorylation of Grin2a 1 0.02 0.63 1.06
137 INT291966 Pag1 Positive_regulation of Gene_expression of Grin2b 1 0.19 1.91 1.06
138 INT317531 Regulation of Binding of Grin1 and Mors1 1 0.08 0.06 1.05
139 INT317534 Regulation of Binding of Camk2a and Grin1 1 0.20 0.06 1.05
140 INT256293 Binding of Grin2b and Insrr 1 0.01 1.06 1.05
141 INT269199 Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.03 0.56 1.05
142 INT154846 Negative_regulation of Mapk14 Negative_regulation of Positive_regulation of Trpv1 1 0.23 0.07 1.05
143 INT60794 Binding of TREH and Chrna9 1 0.00 0 1.04
144 INT317535 Binding of Grin1 and Mors1 1 0.07 0.06 1.04
145 INT291964 Phex Regulation of Gene_expression of Grin2b 1 0.08 1.39 1.04
146 INT130167 Trpv1 Regulation of Localization of Calca 2 0.38 0.69 1.03
147 INT346835 Gene_expression of Efnb2 Positive_regulation of Phosphorylation of Grin2b 1 0.27 1.07 1.03
148 INT114553 Binding of Trpv1 and Col4a4 1 0.01 0.44 1.03
149 INT114554 Binding of St3gal3 and Trpv1 1 0.01 0.44 1.03
150 INT134384 Trpa1 Negative_regulation of Gene_expression of Trpm8 1 0.47 1.21 1.02
151 INT269194 Ceacam3 Positive_regulation of Phosphorylation of Grin1 1 0.09 0.55 1.02
152 INT148327 Binding of Pkd1 and Trpv1 1 0.52 2.23 1.01
153 INT131173 Chrna7 Positive_regulation of Localization of Abat 1 0.10 0 1.01
154 INT131889 gr Regulation of Gene_expression of Grin1 1 0.02 0 1.01
155 INT186161 Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.11 1.05 1.01
156 INT353690 Binding of Grin2b and Ca2 1 0.14 1.17 1.01
157 INT166625 Acer3 Positive_regulation of Trpa1 1 0.01 1.91 1
158 INT317532 Grin1 Regulation of Negative_regulation of Oprm1 1 0.18 0.07 1
159 INT46645 Binding of Gabrg1 and Chrm5 1 0.29 0.09 1
160 INT283932 Positive_regulation of Mapk14 Regulation of Gene_expression of Trpv1 1 0.14 1.28 0.99
161 INT156510 Nfkb1 Regulation of Positive_regulation of Grin1 1 0.03 0.98 0.98
162 INT344389 Ephb2 Positive_regulation of Phosphorylation of Grin2b 1 0.16 1.46 0.98
163 INT156508 Nfkb1 Regulation of Positive_regulation of Grin1 1 0.22 0.98 0.98
164 INT353372 Dio1 Positive_regulation of Grin1 1 0.16 0 0.98
165 INT307100 Trpv1 Regulation of Binding of Trpa1 1 0.31 1.81 0.97
166 INT156380 Regulation of Binding of Grin1 and Dlg4 1 0.29 0.32 0.97
167 INT307103 Trpa1 Regulation of Binding of Trpv1 1 0.31 1.81 0.97
168 INT122144 Binding of Trpv1 and Prkd1 1 0.02 0.39 0.96
169 INT152084 Edn1 Negative_regulation of Positive_regulation of Trpv1 1 0.62 0.48 0.96
170 INT274899 Positive_regulation of P2rx4 Positive_regulation of Localization of Gtf3a 1 0.02 1.67 0.95
171 INT169096 Hpcl1 Regulation of Gene_expression of Slc12a5 1 0.02 0.05 0.95
172 INT354224 Bdnf Positive_regulation of Transcription of Accn3 1 0.09 1.04 0.95
173 INT156608 Trpv1 Regulation of Nav1 1 0.51 0.52 0.95
174 INT136033 Edn1 Positive_regulation of Trpv1 1 0.50 0.34 0.95
175 INT144902 Binding of Trpv1 and Pars2 1 0.17 0 0.95
176 INT281085 Binding of Gria2 and Nsf 2 0.26 0.4 0.94
177 INT149389 Olfr1241 Positive_regulation of Trpa1 1 0.02 0.31 0.94
178 INT214408 ATP1A4 Regulation of DNAH8 1 0.04 1.01 0.94
179 INT199396 Prok2 Regulation of Trpv1 1 0.43 1.23 0.94
180 INT149390 Foxm1 Positive_regulation of Trpa1 1 0.28 0.31 0.94
181 INT344381 Olfr360 Negative_regulation of Gene_expression of Grin2b 1 0.01 1.17 0.93
182 INT214409 ATP1A4 Regulation of CAPN1 1 0.01 1.01 0.93
183 INT344390 Olfr360 Negative_regulation of Phosphorylation of Grin2b 1 0.01 1.17 0.93
184 INT221916 RPS3AP18 Negative_regulation of Positive_regulation of Trpa1 1 0.00 0.75 0.93
185 INT344388 Efnb1 Positive_regulation of Phosphorylation of Grin2b 1 0.40 1.45 0.92
186 INT122269 Src Negative_regulation of Positive_regulation of Grin2b 1 0.27 0.44 0.92
187 INT251153 Dlg2 Positive_regulation of Gene_expression of Grin2a 1 0.40 0.6 0.92
188 INT80718 Trpv3 Negative_regulation of Chn1 1 0.01 0.7 0.92
189 INT195927 Binding of Prkaca and Trpv1 1 0.07 0.28 0.92
190 INT251152 Dlg2 Positive_regulation of Localization of Grin2b 1 0.43 0.6 0.92
191 INT215584 P2rx1 Regulation of Localization of Gabrg1 1 0.01 0 0.92
192 INT291962 Pag1 Negative_regulation of Gene_expression of Grin2b 1 0.17 1.56 0.92
193 INT109842 Prkce Positive_regulation of Localization of Trpv1 1 0.13 1.31 0.91
194 INT122266 Src Negative_regulation of Grin2b 1 0.27 0.43 0.91
195 INT281082 Binding of Gria2 and Ltp 1 0.24 0.6 0.9
196 INT108647 Binding of Grin2a and Camk1d 1 0.33 0.78 0.9
197 INT180772 Bdnf Regulation of Trpv1 1 0.11 0.29 0.9
198 INT180777 Bdnf Regulation of Gene_expression of Trpv1 1 0.18 0.29 0.9
199 INT108438 Grin2b Regulation of Pdyn 1 0.16 0.25 0.9
200 INT292988 Negative_regulation of SGCG Positive_regulation of GABRB3 1 0.01 0.3 0.89

Single Events

The table below shows the top 100 pain related interactions that have been reported for ion transmembrane transport. They are ordered first by their pain relevance and then by number of times they were reported in ion transmembrane transport. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT58061 Gene_expression of Trpv1 1117 0.78 451.54 637.59
2 INT64202 Positive_regulation of Trpv1 643 0.70 249.66 397.42
3 INT76660 Gene_expression of Trpv1 691 0.78 329.46 386.42
4 INT87687 Positive_regulation of Trpv1 409 0.70 210.24 257.59
5 INT49134 Gene_expression of Grin1 270 0.78 84.78 148.61
6 INT90910 Phosphorylation of Grin1 150 0.82 68.23 139.24
7 INT60126 Regulation of Trpv1 186 0.62 85.53 133.4
8 INT64201 Negative_regulation of Trpv1 203 0.59 79.18 119.75
9 INT7341 Positive_regulation of Grin1 169 0.70 65.86 118.38
10 INT89054 Positive_regulation of Gene_expression of Trpv1 156 0.70 90.78 102.03
11 INT104000 Phosphorylation of Grin2b 73 0.82 48.34 93.48
12 INT38731 Localization of Trpv1 138 0.81 52.73 90.49
13 INT4830 Binding of Trpv1 158 0.48 45.11 84.2
14 INT92518 Gene_expression of Grin2b 131 0.78 65.52 80.91
15 INT123584 Gene_expression of Trpa1 176 0.78 83 78.65
16 INT25363 Negative_regulation of Trpv1 144 0.59 64.78 75.7
17 INT98621 Regulation of Trpv1 121 0.62 79.24 75.23
18 INT79506 Gene_expression of Grin2b 122 0.78 43.71 73.42
19 INT117601 Positive_regulation of Trpa1 174 0.70 72.41 71.9
20 INT87686 Positive_regulation of Gene_expression of Trpv1 101 0.70 72.41 69.15
21 INT96622 Localization of Trpv1 110 0.81 59.82 63.25
22 INT109431 Gene_expression of Trpa1 123 0.78 51.84 59.98
23 INT90911 Positive_regulation of Phosphorylation of Grin1 62 0.70 27.45 59.26
24 INT62960 Gene_expression of P2rx2 149 0.77 58.31 59.16
25 INT7340 Regulation of Grin1 87 0.62 30.37 57.93
26 INT4957 Negative_regulation of Grin1 87 0.59 24.51 53.21
27 INT49520 Gene_expression of P2rx3 121 0.78 61.15 49.24
28 INT109430 Positive_regulation of Trpa1 119 0.70 44 49.14
29 INT121416 Gene_expression of Trpm8 101 0.78 52.7 47.85
30 INT51627 Gene_expression of Grin2a 82 0.76 25.09 47.6
31 INT57021 Positive_regulation of Gene_expression of Grin1 62 0.70 24.77 47.31
32 INT98498 Binding of Trpv1 75 0.48 33.67 44.4
33 INT94029 Positive_regulation of Grin2b 58 0.70 24.2 42.52
34 INT81251 Gene_expression of Trpv2 78 0.78 28.27 41.76
35 INT92517 Gene_expression of Grin1 105 0.78 29.53 39.43
36 INT92515 Gene_expression of Grin2a 84 0.76 26.68 38.37
37 INT58062 Negative_regulation of Gene_expression of Trpv1 66 0.59 22.34 38.02
38 INT82054 Positive_regulation of Grin2b 56 0.70 17.45 37.14
39 INT11246 Binding of Grin1 65 0.48 14.53 36.93
40 INT80075 Regulation of Gene_expression of Trpv1 55 0.62 32.42 36.88
41 INT103172 Gene_expression of Slc12a5 81 0.77 39.45 36.22
42 INT64436 Gene_expression of P2rx1 93 0.78 32.69 36.12
43 INT103998 Positive_regulation of Phosphorylation of Grin2b 33 0.69 19.08 36.08
44 INT23330 Binding of Chrna7 79 0.48 10.06 35.5
45 INT98521 Gene_expression of Accn2 52 0.74 23.45 35.09
46 INT130479 Phosphorylation of Grin2b 28 0.77 34.82 34.97
47 INT76531 Transcription of Trpv1 62 0.72 23.69 34.77
48 INT52194 Positive_regulation of Grin1 83 0.69 25.09 34.76
49 INT49519 Gene_expression of P2rx7 84 0.76 36.88 34.69
50 INT12161 Positive_regulation of P2rx2 70 0.69 34.22 34.4
51 INT96624 Positive_regulation of Positive_regulation of Trpv1 62 0.70 20.5 34.28
52 INT57024 Regulation of Gene_expression of Grin1 32 0.62 9.77 32.6
53 INT93451 Positive_regulation of Gene_expression of Grin2b 43 0.70 29.09 31.89
54 INT117632 Gene_expression of Trpm8 99 0.78 29.41 30.9
55 INT70776 Positive_regulation of P2rx1 62 0.62 32.55 30.75
56 INT64918 Gene_expression of Gria2 108 0.74 29.95 29.67
57 INT106540 Negative_regulation of Phosphorylation of Grin1 15 0.58 9.32 29.13
58 INT56525 Gene_expression of Gria2 74 0.75 23.15 28.6
59 INT98522 Gene_expression of Accn3 68 0.78 26.95 28.6
60 INT93033 Negative_regulation of Grin2b 48 0.58 20.94 28.54
61 INT149387 Negative_regulation of Trpa1 55 0.59 21.91 28.31
62 INT80470 Negative_regulation of Gene_expression of Grin1 33 0.59 10.22 27.15
63 INT86789 Gene_expression of P2rx4 46 0.77 30.66 25.68
64 INT112036 Phosphorylation of Trpv1 51 0.82 18.59 25.6
65 INT103320 Positive_regulation of Positive_regulation of Trpv1 44 0.70 27.73 25.28
66 INT92105 Transcription of Trpv1 47 0.71 27.47 25.01
67 INT107577 Negative_regulation of Grin2b 32 0.59 12.35 24.88
68 INT117600 Positive_regulation of Trpm8 65 0.70 31.96 24.46
69 INT101225 Positive_regulation of Gria2 62 0.64 28.1 23.93
70 INT100124 Gene_expression of Accn3 38 0.78 30.02 23.63
71 INT125190 Regulation of Gene_expression of Trpv1 38 0.62 32.57 23.2
72 INT88327 Gene_expression of P2rx7 109 0.77 48.86 22.41
73 INT89056 Phosphorylation of Trpv1 46 0.82 13.52 22.16
74 INT112427 Positive_regulation of P2rx4 27 0.68 26.29 21.31
75 INT102281 Positive_regulation of Gene_expression of Grin2b 27 0.70 10.38 20.84
76 INT103169 Negative_regulation of Slc12a5 38 0.58 27.75 20.81
77 INT96511 Negative_regulation of Positive_regulation of Trpv1 35 0.59 10.95 19.79
78 INT23787 Positive_regulation of P2rx7 36 0.68 23.54 19.45
79 INT91916 Gene_expression of P2rx3 51 0.78 21.2 19.05
80 INT90612 Positive_regulation of Grin2a 33 0.65 15.11 18.84
81 INT12269 Gene_expression of Chrna9 39 0.73 6.98 18.44
82 INT50420 Transcription of Grin1 30 0.71 13.21 18.28
83 INT90937 Negative_regulation of Gene_expression of Trpv1 34 0.59 22.74 18.12
84 INT21132 Gene_expression of GABRB3 36 0.33 11.32 17.61
85 INT63928 Negative_regulation of Grin1 51 0.56 11.81 17.57
86 INT78233 Positive_regulation of P2rx3 36 0.56 21.49 17.25
87 INT16624 Localization of Grin1 38 0.79 8.46 17.15
88 INT111416 Positive_regulation of Trpm8 65 0.70 14.62 17.13
89 INT95930 Negative_regulation of Gria2 63 0.56 18.37 17.04
90 INT134596 Regulation of Trpa1 32 0.62 18.78 17.02
91 INT93037 Regulation of Grin2b 26 0.57 11.9 16.92
92 INT92514 Regulation of Grin2b 22 0.50 11.07 16.92
93 INT88356 Negative_regulation of Positive_regulation of Grin1 16 0.58 4.72 16.58
94 INT62861 Regulation of Gria2 45 0.60 13.35 16.07
95 INT91285 Negative_regulation of P2rx2 29 0.57 12.74 15.48
96 INT69652 Regulation of P2rx3 26 0.61 17.17 15.4
97 INT92839 Regulation of P2rx2 36 0.45 13.19 15.38
98 INT143276 Phosphorylation of Gria2 42 0.80 16.07 15.2
99 INT114510 Positive_regulation of Gria2 36 0.57 14.91 14.85
100 INT14647 Positive_regulation of Grin2a 26 0.67 4.69 14.8
101 INT103170 Negative_regulation of Gene_expression of Slc12a5 26 0.58 17.25 14.4
102 INT115071 Positive_regulation of Accn3 14 0.70 16.56 14.24
103 INT92513 Regulation of Grin1 26 0.59 9.12 13.94
104 INT7342 Positive_regulation of Positive_regulation of Grin1 18 0.50 9.22 13.76
105 INT90942 Regulation of P2rx1 31 0.61 16.61 13.69
106 INT121241 Positive_regulation of P2rx7 65 0.69 40.94 13.59
107 INT97848 Positive_regulation of Localization of Trpv1 18 0.50 7.66 13.36
108 INT233113 Regulation of Trpm8 24 0.61 18.08 13.17
109 INT101494 Regulation of Positive_regulation of Trpv1 18 0.62 6.57 12.9
110 INT103996 Negative_regulation of Phosphorylation of Grin2b 11 0.58 7.81 12.85
111 INT119089 Regulation of Phosphorylation of Grin1 17 0.61 3.1 12.82
112 INT78234 Positive_regulation of Gene_expression of P2rx2 18 0.69 12.86 12.75
113 INT103997 Phosphorylation of Grin2a 17 0.64 10.75 12.67
114 INT122117 Negative_regulation of Gene_expression of Grin2b 20 0.59 11.3 12.55
115 INT120432 Regulation of Trpa1 22 0.61 9.65 12.36
116 INT81249 Positive_regulation of Trpv2 21 0.70 8.13 12.36
117 INT100799 Negative_regulation of Grin2a 27 0.57 7.33 12.2
118 INT112103 Binding of Grin1 28 0.48 4.21 12.08
119 INT145515 Positive_regulation of Localization of Trpv1 23 0.50 10.12 12.08
120 INT96406 Regulation of Trpv2 14 0.62 7.45 12.04
121 INT122053 Positive_regulation of P2rx4 16 0.69 13.02 11.98
122 INT51625 Regulation of Gene_expression of Grin2a 12 0.60 3.28 11.6
123 INT98524 Positive_regulation of Accn2 15 0.49 9.48 11.57
124 INT138639 Gene_expression of Hcn4 32 0.75 13.85 11.25
125 INT68290 Gene_expression of Accn1 32 0.73 7.36 11.23
126 INT259165 Phosphorylation of Gria2 4 0.65 11.65 11.07
127 INT57069 Regulation of Gria2 28 0.44 10.11 11.06
128 INT130475 Positive_regulation of Phosphorylation of Grin2b 8 0.47 11.52 10.96
129 INT143767 Negative_regulation of Trpm8 26 0.58 12.34 10.83
130 INT78579 Negative_regulation of P2rx3 23 0.59 10.13 10.78
131 INT23675 Negative_regulation of Binding of Chrna7 18 0.37 0.5 10.74
132 INT65009 Gene_expression of HTR3A 29 0.75 8.51 10.59
133 INT112037 Negative_regulation of Positive_regulation of Trpv1 19 0.59 8.9 10.55
134 INT51626 Transcription of Grin2a 16 0.68 1.65 10.5
135 INT93036 Negative_regulation of Grin2a 23 0.50 7.1 10.32
136 INT64193 Regulation of Grin2a 19 0.54 2.98 10.31
137 INT109578 Positive_regulation of Accn3 16 0.70 9.09 10.05
138 INT80717 Gene_expression of Trpv3 20 0.72 10.05 9.96
139 INT115614 Binding of Gria2 25 0.43 8.97 9.91
140 INT73427 Localization of P2rx7 24 0.79 8.65 9.87
141 INT134597 Binding of Trpa1 21 0.48 9.41 9.74
142 INT80006 Regulation of Gene_expression of Grin2b 8 0.57 3.75 9.62
143 INT112428 Positive_regulation of Gene_expression of P2rx4 12 0.68 12.67 9.57
144 INT105304 Negative_regulation of Gene_expression of P2rx2 11 0.28 11.07 9.53
145 INT23676 Gene_expression of Chrna7 47 0.75 23.66 9.51
146 INT116705 Positive_regulation of Positive_regulation of P2rx2 13 0.49 9.44 9.47
147 INT89053 Positive_regulation of Phosphorylation of Trpv1 16 0.70 8.89 9.39
148 INT168991 Negative_regulation of P2rx4 9 0.43 12.77 9.39
149 INT259169 Positive_regulation of Phosphorylation of Gria2 3 0.40 9.98 9.34
150 INT107898 Gene_expression of Trpv2 27 0.76 10.55 9.28
151 INT78769 Regulation of Grin2a 16 0.58 5.22 9.28
152 INT93191 Gene_expression of Accn2 22 0.76 10.04 8.91
153 INT121987 Phosphorylation of Grin1 11 0.80 4.73 8.88
154 INT78578 Localization of P2rx3 21 0.78 9.55 8.86
155 INT146346 Negative_regulation of Gene_expression of Trpa1 15 0.59 11.76 8.83
156 INT146241 Positive_regulation of Gene_expression of Trpa1 23 0.69 8.07 8.74
157 INT120651 Positive_regulation of Gene_expression of Accn2 13 0.66 9.02 8.58
158 INT70775 Positive_regulation of Positive_regulation of P2rx1 15 0.49 8.65 8.49
159 INT48257 Negative_regulation of P2rx7 18 0.41 7.82 8.42
160 INT134381 Regulation of Trpm8 25 0.54 8.31 8.25
161 INT112104 Binding of Grin2b 21 0.44 6.78 8.16
162 INT78766 Negative_regulation of Gria2 20 0.52 6.27 8.12
163 INT117642 Regulation of Gene_expression of Grin1 18 0.53 7.09 8.08
164 INT130502 Negative_regulation of Trpa1 17 0.59 5.75 8.06
165 INT136177 Gene_expression of P2rx4 8 0.75 6.74 8.05
166 INT95172 Localization of P2rx1 14 0.78 6.77 7.81
167 INT135113 Localization of Grin1 18 0.73 3.73 7.69
168 INT59333 Positive_regulation of Chrna9 14 0.64 3.23 7.64
169 INT18393 Negative_regulation of Ryr1 15 0.43 3.63 7.57
170 INT138890 Regulation of Slc12a5 12 0.45 11.61 7.46
171 INT110705 Positive_regulation of Positive_regulation of Grin1 11 0.69 4.7 7.33
172 INT102080 Positive_regulation of P2rx3 20 0.67 6.91 7.3
173 INT134379 Binding of Trpa1 13 0.48 7.16 7.27
174 INT114509 Transcription of Gria2 10 0.58 0.75 7.27
175 INT90943 Negative_regulation of P2rx1 13 0.42 8.21 7.22
176 INT16268 Binding of HTR3A 15 0.47 7.38 7.18
177 INT114014 Positive_regulation of Gene_expression of P2rx1 13 0.69 7.77 7.15
178 INT88079 Gene_expression of Chrna4 20 0.76 8.52 6.98
179 INT131745 Positive_regulation of Gene_expression of Trpa1 13 0.69 8.07 6.95
180 INT91351 Gene_expression of P2rx1 28 0.75 5.89 6.78
181 INT78232 Binding of P2rx3 25 0.41 6.26 6.78
182 INT126989 Transcription of Accn2 8 0.63 5.22 6.77
183 INT120261 Binding of P2rx2 19 0.28 5.8 6.72
184 INT126484 Localization of Trpa1 15 0.80 4.08 6.64
185 INT112430 Negative_regulation of P2rx4 9 0.57 8.4 6.63
186 INT154773 Regulation of Accn3 7 0.62 7.09 6.63
187 INT136496 Regulation of Accn3 5 0.45 3.72 6.53
188 INT131744 Transcription of Trpa1 9 0.68 7.67 6.47
189 INT539 Negative_regulation of Chrna7 14 0.42 4.59 6.42
190 INT100926 Positive_regulation of Gene_expression of Grin2a 11 0.63 3.24 6.41
191 INT93193 Positive_regulation of Accn2 16 0.69 7.2 6.37
192 INT93195 Negative_regulation of Accn2 14 0.59 7.23 6.31
193 INT139580 Negative_regulation of Trpm8 19 0.58 3.8 6.26
194 INT88326 Negative_regulation of P2rx7 16 0.58 8.77 6.25
195 INT103171 Positive_regulation of Slc12a5 15 0.51 3.6 6.25
196 INT94608 Regulation of P2rx7 19 0.23 8.06 6.19
197 INT68882 Binding of P2rx7 16 0.23 4.33 6.17
198 INT100658 Negative_regulation of Positive_regulation of Grin2b 7 0.41 1.39 6.17
199 INT16568 Positive_regulation of HTR3A 14 0.67 4.82 6.01
200 INT103319 Regulation of Positive_regulation of Trpv1 11 0.45 8.37 5.99
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