GO:0034244

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Name negative regulation of transcription elongation from RNA polymerase II promoter
Categary Process
Go Slim No
Go Link GO:0034244
Unique Molecular Interactions 74
Total Molecular Interactions 105
Total Single Events 857
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of transcription elongation from RNA polymerase II promoter. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of transcription elongation from RNA polymerase II promoter. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT135176 Myst2 Regulation of Gene_expression of Hif1a 1 0.24 0.47 0.47
2 INT135178 Myst2 Regulation of Hif1a 1 0.24 0.44 0.44
3 INT198566 Ddit4l Regulation of Axin1 1 0.03 1 0.31
4 INT256629 Binding of Ptch1 and Shh 7 0.42 4.22 0.19
5 INT217074 Binding of Acsm3 and Axin1 1 0.00 5.37 0.17
6 INT237418 Binding of Hif1a and Bace1 1 0.06 1.18 0.15
7 INT323434 Osr1 Regulation of Hif1a 1 0.01 0.79 0.13
8 INT323433 Osr1 Regulation of Protein_catabolism of Hif1a 1 0.01 0.8 0.13
9 INT232787 CYBB Positive_regulation of Positive_regulation of Hif1a 1 0.01 0.66 0.12
10 INT323431 Binding of Hif1a and Vhl 1 0.07 0.68 0.12
11 INT249923 Binding of Pah and Hif1a 1 0.31 1.16 0.12
12 INT249920 Negative_regulation of Binding of Pah and Hif1a 1 0.37 0.76 0.08
13 INT270464 Binding of Shh and Smo 1 0.07 1.3 0.08
14 INT290906 Shh Positive_regulation of Egfr 1 0.23 0 0.08
15 INT247578 Hif1a Regulation of VEGFA 1 0.02 1.59 0.07
16 INT298349 HES3 Positive_regulation of Shh 1 0.12 0.14 0.07
17 INT290905 Gene_expression of Shh Positive_regulation of Gene_expression of Angpt1 1 0.14 0 0.06
18 INT308328 Hif1a Regulation of Positive_regulation of Trib3 1 0.02 0.89 0.05
19 INT304322 Hif1a Positive_regulation of Positive_regulation of VEGFA 1 0.11 0.39 0.05
20 INT249921 Binding of Hif1a and Asph 1 0.05 0.41 0.04
21 INT213563 Binding of Ctnnd2 and Shh 1 0.27 0.09 0.04
22 INT270459 Binding of Shh and Gli1 1 0.02 0.65 0.04
23 INT352014 Shh Positive_regulation of Gene_expression of Pax1 1 0.29 0.07 0.03
24 INT297159 Gsta3 Negative_regulation of Hif1a 1 0.00 0.54 0.03
25 INT322471 Hif1a Positive_regulation of VEGFA 1 0.05 0.26 0.03
26 INT311655 Shh Positive_regulation of Gene_expression of Fgf8 1 0.31 0.18 0.03
27 INT270462 Shh Positive_regulation of Ccnd1 1 0.10 0.6 0.03
28 INT213559 Binding of Egf and Shh 1 0.17 0.07 0.03
29 INT247576 Binding of Hif1a and Vbp1 1 0.01 0.6 0
30 INT290910 Pkm2 Negative_regulation of Shh 1 0.07 0.06 0
31 INT135174 Myst2 Positive_regulation of Binding of Hif1a 1 0.41 0 0
32 INT205963 GLI1 Positive_regulation of Negative_regulation of SHH 1 0.22 0.58 0
33 INT314850 Shh Regulation of Atoh7 1 0.45 0.22 0
34 INT290908 Regulation of Shh Positive_regulation of Ntn1 1 0.12 0 0
35 INT339096 Ezh2 Regulation of Rcc1 1 0.02 1.1 0
36 INT290911 Gene_expression of Shh Positive_regulation of Pkm2 1 0.07 0 0
37 INT247574 Ube2e3 Positive_regulation of Hif1a 1 0.04 0.62 0
38 INT290904 Shh Positive_regulation of Prkcg 1 0.26 0.06 0
39 INT290900 Prkcg Regulation of Shh 1 0.23 0 0
40 INT205960 Binding of PTCH1 and SHH 1 0.21 0.71 0
41 INT287885 Binding of DVL1 and AXIN1 1 0.02 0 0
42 INT290944 Shh Positive_regulation of VEGFA 1 0.04 0.05 0
43 INT247575 Binding of Epo and Hif1a 1 0.09 1.24 0
44 INT270461 Shh Regulation of Gene_expression of Ptch1 1 0.48 0.07 0
45 INT135175 Myst2 Positive_regulation of Hif1a 1 0.41 0 0
46 INT260496 Hif1a Regulation of Gene_expression of VEGFA 1 0.12 0.93 0
47 INT236724 Binding of AXIN1 and Ctnnd2 1 0.39 1.03 0
48 INT205959 Binding of SHH and SMOX 1 0.12 0.72 0
49 INT249924 Cpox Positive_regulation of Hif1a 1 0.01 0.68 0
50 INT262710 Binding of Crem and Hif1a 1 0.00 1.85 0
51 INT270471 Shh Regulation of VEGFA 1 0.39 0.08 0
52 INT290898 Shh Positive_regulation of Nos2 1 0.46 0.05 0
53 INT270466 Ptch1 Regulation of Gene_expression of Shh 1 0.48 0.07 0
54 INT322470 Binding of Bcl6 and Hif1a 1 0.06 0.52 0
55 INT270460 Shh Positive_regulation of Gene_expression of Angpt1 1 0.04 0.08 0
56 INT270470 Shh Regulation of Gene_expression of VEGFA 1 0.39 0.15 0
57 INT290907 Shh Positive_regulation of Ntn1 1 0.32 0.05 0
58 INT205977 Binding of SHH and Ptch1 1 0.31 0.71 0
59 INT270469 Shh Positive_regulation of VEGFA 1 0.29 0.12 0
60 INT270468 Shh Positive_regulation of Gene_expression of VEGFA 1 0.44 0.08 0
61 INT264737 Hes1 Regulation of Shh 1 0.19 0.13 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of transcription elongation from RNA polymerase II promoter. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of transcription elongation from RNA polymerase II promoter. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT135170 Positive_regulation of Hif1a 86 0.67 99.4 6.07
2 INT112713 Gene_expression of Hif1a 24 0.75 20.48 5.45
3 INT135172 Gene_expression of Hif1a 56 0.76 46.49 5.44
4 INT112704 Positive_regulation of Hif1a 25 0.67 21.49 4.23
5 INT134756 Positive_regulation of Gene_expression of Hif1a 8 0.50 11.14 2.68
6 INT144973 Gene_expression of Shh 9 0.77 4.32 1.96
7 INT208561 Gene_expression of Shh 51 0.78 9.57 1.77
8 INT122597 Transcription of Hif1a 5 0.69 5.56 1.63
9 INT153723 Negative_regulation of Gene_expression of Hif1a 2 0.41 1.25 1.58
10 INT135171 Positive_regulation of Gene_expression of Hif1a 15 0.68 16.95 1.51
11 INT232785 Localization of Hif1a 8 0.46 10.37 1.33
12 INT253191 Positive_regulation of Gene_expression of Shh 2 0.66 2.57 1.14
13 INT165530 Positive_regulation of Shh 4 0.69 1.21 1.05
14 INT135169 Binding of Hif1a 22 0.47 12.48 0.79
15 INT233837 Negative_regulation of Hif1a 9 0.26 12.72 0.65
16 INT112708 Negative_regulation of Hif1a 5 0.38 2.7 0.64
17 INT136465 Regulation of Hif1a 5 0.39 7.05 0.62
18 INT135173 Regulation of Gene_expression of Hif1a 3 0.44 2.49 0.53
19 INT134758 Positive_regulation of Transcription of Hif1a 2 0.33 2.44 0.53
20 INT153065 Regulation of Hif1a 8 0.28 8.57 0.51
21 INT153067 Positive_regulation of Positive_regulation of Hif1a 10 0.49 11.83 0.47
22 INT206484 Localization of Shh 2 0.75 1.14 0.46
23 INT210125 Regulation of Axin1 1 0.02 2.45 0.46
24 INT232798 Positive_regulation of Gene_expression of Shh 7 0.70 1.49 0.44
25 INT208559 Negative_regulation of Gene_expression of Shh 8 0.43 1.58 0.38
26 INT247549 Transcription of Hif1a 7 0.42 8.77 0.36
27 INT320784 Protein_catabolism of Hif1a 3 0.61 2.41 0.34
28 INT247563 Negative_regulation of Positive_regulation of Hif1a 1 0.16 9.12 0.32
29 INT232786 Positive_regulation of Localization of Hif1a 2 0.31 2.63 0.27
30 INT232795 Positive_regulation of Shh 2 0.70 3.68 0.26
31 INT183062 Gene_expression of SHH 12 0.65 5.28 0.21
32 INT134477 Negative_regulation of SHH 2 0.37 1.13 0.2
33 INT247564 Positive_regulation of Transcription of Hif1a 1 0.19 2.05 0.2
34 INT210123 Localization of Axin1 1 0.04 0.84 0.17
35 INT66933 Binding of AXIN1 6 0.32 1.8 0.16
36 INT232799 Regulation of Gene_expression of Shh 3 0.27 1.04 0.16
37 INT253177 Negative_regulation of Gene_expression of Shh 2 0.55 0.63 0.16
38 INT249919 Regulation of Regulation of Hif1a 2 0.29 1.81 0.14
39 INT249908 Binding of Hif1a 2 0.31 1.48 0.14
40 INT263410 Negative_regulation of Axin1 1 0.01 0 0.14
41 INT253190 Localization of Shh 2 0.77 1.06 0.13
42 INT249913 Regulation of Gene_expression of Hif1a 2 0.32 1.82 0.13
43 INT253183 Negative_regulation of Shh 8 0.55 2.13 0.12
44 INT153064 Positive_regulation of Regulation of Hif1a 1 0.45 1.52 0.1
45 INT260478 Negative_regulation of Positive_regulation of Hif1a 2 0.30 1.23 0.09
46 INT270442 Transcription of Shh 1 0.53 0.25 0.09
47 INT260462 Negative_regulation of Binding of Hif1a 1 0.30 1.13 0.09
48 INT213515 Binding of Shh 8 0.37 1.92 0.08
49 INT294014 Regulation of AXIN1 3 0.24 1.04 0.08
50 INT145364 Negative_regulation of AXIN1 2 0.33 0.52 0.08
51 INT260451 Positive_regulation of Positive_regulation of Hif1a 1 0.36 1.01 0.08
52 INT270453 Regulation of Shh 1 0.27 0.83 0.08
53 INT205973 Binding of SHH 3 0.35 1.03 0.07
54 INT297157 Negative_regulation of Negative_regulation of Hif1a 1 0.03 0.54 0.07
55 INT247560 Negative_regulation of Negative_regulation of Hif1a 1 0.16 2.06 0.07
56 INT256862 Regulation of Shh 1 0.25 0 0.07
57 INT247553 Regulation of Negative_regulation of Hif1a 1 0.17 1.36 0.06
58 INT297158 Regulation of Localization of Hif1a 1 0.03 0.32 0.06
59 INT247559 Regulation of Positive_regulation of Hif1a 2 0.23 1.64 0.05
60 INT247555 Positive_regulation of Binding of Hif1a 2 0.31 1.15 0.05
61 INT270445 Positive_regulation of Localization of Shh 1 0.44 0.13 0.05
62 INT339094 Gene_expression of Ezh2 1 0.78 67.79 0.05
63 INT244699 Positive_regulation of AXIN1 1 0.02 0 0.05
64 INT297156 Localization of Hif1a 1 0.06 0.32 0.05
65 INT322464 Regulation of Localization of Hif1a 1 0.28 0.59 0.05
66 INT181793 Positive_regulation of SHH 3 0.67 2.59 0.04
67 INT208560 Negative_regulation of Shh 2 0.59 2.22 0.04
68 INT249918 Regulation of Protein_catabolism of Hif1a 1 0.29 0.4 0.04
69 INT249916 Protein_catabolism of Hif1a 1 0.64 0.39 0.04
70 INT253187 Negative_regulation of Transcription of Shh 1 0.41 0.55 0.03
71 INT253181 Transcription of Shh 1 0.68 0.54 0.03
72 INT294025 Phosphorylation of AXIN1 2 0.38 0.47 0
73 INT287932 Negative_regulation of Binding of AXIN1 1 0.12 0 0
74 INT339087 Binding of Ezh2 1 0.37 1.14 0
75 INT249915 Regulation of Positive_regulation of Hif1a 1 0.29 0.85 0
76 INT112706 Negative_regulation of Gene_expression of Hif1a 1 0.08 0 0
77 INT322450 Negative_regulation of Binding of Hif1a 1 0.26 0.32 0
78 INT290918 Negative_regulation of Positive_regulation of Shh 1 0.41 0.25 0
79 INT339090 Positive_regulation of Ezh2 1 0.47 0.82 0
80 INT230972 Positive_regulation of Gene_expression of SHH 1 0.18 0.07 0
81 INT249917 Regulation of Negative_regulation of Hif1a 1 0.29 0.29 0
82 INT290929 Binding of Shh 1 0.31 0.1 0
83 INT290927 Regulation of Positive_regulation of Shh 1 0.23 0 0
84 INT339091 Positive_regulation of Gene_expression of Ezh2 1 0.70 11.65 0
85 INT339095 Negative_regulation of Gene_expression of Ezh2 1 0.59 4.48 0
86 INT339089 Regulation of Gene_expression of Ezh2 1 0.45 3.76 0
87 INT287935 Positive_regulation of Binding of AXIN1 1 0.14 0 0
88 INT270449 Negative_regulation of Positive_regulation of Shh 1 0.43 0.24 0
89 INT247562 Negative_regulation of Transcription of Hif1a 1 0.16 2.39 0
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