GO:0034329

From wiki-pain
Jump to: navigation, search
Name cell junction assembly
Categary Process
Go Slim No
Go Link GO:0034329
Unique Molecular Interactions 82
Total Molecular Interactions 96
Total Single Events 1236
Pain Genes Associated 27

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cell junction assembly. They are ordered first by their pain relevance and then by number of times they were reported for cell junction assembly. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT153589 Binding of PRKCI and Oprm1 1 0.06 0 1.17
2 INT113946 Binding of FLNA and OPRM1 1 0.10 0.37 0.9
3 INT90381 Binding of GH1 and LAMC2 1 0.34 0.05 0.81
4 INT106992 F2 Positive_regulation of PARD3 3 0.05 1.83 0.72
5 INT12238 CCK Positive_regulation of CDH2 1 0.02 0 0.7
6 INT333991 Binding of FLNA and SELL 1 0.00 1.69 0.55
7 INT222691 Negative_regulation of Binding of FLNA and TNF 1 0.14 1.92 0.54
8 INT222692 Binding of FLNA and TNF 1 0.12 1.92 0.53
9 INT220188 EC Positive_regulation of CADM1 1 0.00 1.72 0.44
10 INT113950 FLNA Regulation of Oprd1 1 0.00 0.16 0.32
11 INT44091 Binding of ACTN1 and CAMSAP2 1 0.08 0 0.28
12 INT345008 Binding of ACTN1 and CSF2 1 0.02 0.53 0.26
13 INT198648 VCAM1 Positive_regulation of CADM1 1 0.00 1.1 0.25
14 INT60524 IFNGR2 Positive_regulation of FERMT2 1 0.04 1.87 0.25
15 INT198644 TNF Positive_regulation of CADM1 1 0.02 1.07 0.24
16 INT198643 CD36 Positive_regulation of CADM1 1 0.01 1.07 0.24
17 INT178074 EDN1 Positive_regulation of Phosphorylation of PXN 1 0.05 0.82 0.2
18 INT267138 Binding of CDH5 and PECAM1 2 0.16 2.69 0.16
19 INT141760 Nfkb1 Regulation of CADM1 1 0.02 1.18 0.16
20 INT141761 Nfkb1 Regulation of Positive_regulation of CADM1 1 0.01 1.21 0.16
21 INT106994 PARD3 Positive_regulation of PAR4 1 0.21 0.28 0.14
22 INT107006 PARD3 Positive_regulation of SPG21 1 0.24 0.29 0.14
23 INT254133 PLEC Regulation of MCRS1 1 0.03 0.33 0.13
24 INT201762 JUP Regulation of Gene_expression of Ccnd1 1 0.03 0.8 0.13
25 INT201791 JUP Regulation of Gene_expression of Myc 1 0.49 0.8 0.13
26 INT106997 PARD3 Positive_regulation of NR1I2 1 0.19 0.28 0.13
27 INT166802 PEG10 Regulation of Gene_expression of LAMC2 1 0.08 0 0.12
28 INT354718 Binding of INADL and Myo18a 1 0.00 0.13 0.12
29 INT177980 CSF1R Regulation of PXN 1 0.07 0.48 0.11
30 INT271525 ITGB1 Positive_regulation of Gopc 1 0.02 0.57 0.11
31 INT355584 VEGFA Positive_regulation of Positive_regulation of CDH5 1 0.06 1.35 0.09
32 INT262939 PAX6 Regulation of CDH4 1 0.02 0.97 0.08
33 INT154168 Binding of KRT5 and Ttf1 1 0.02 0.34 0.08
34 INT262937 PAX6 Regulation of CDH8 1 0.03 0.98 0.08
35 INT137251 BCL2L11 Regulation of CDH1 1 0.17 0.99 0.08
36 INT262944 PAX6 Regulation of CDH6 1 0.03 0.97 0.08
37 INT154161 Binding of GFAP and KRT5 1 0.40 0.34 0.08
38 INT159852 Gene_expression of IL2 Regulation of Gene_expression of ACTN1 1 0.03 0.16 0.07
39 INT339111 Binding of ERBB2 and JUP 1 0.38 0.62 0.07
40 INT339108 Binding of ESR1 and JUP 1 0.38 0.62 0.07
41 INT269210 CDH1 Positive_regulation of Positive_regulation of ITK 1 0.06 0.84 0.06
42 INT250015 Binding of FLNA and Nos3 1 0.05 1.09 0.06
43 INT317416 Binding of FN1 and ITGB1 1 0.47 0.69 0.05
44 INT269214 SNAI1 Positive_regulation of Positive_regulation of CDH1 1 0.35 0.71 0.04
45 INT269211 SNAI1 Positive_regulation of Gene_expression of CDH1 1 0.40 0.73 0.04
46 INT213207 Negative_regulation of ASAP2 Negative_regulation of PVR 1 0.01 0.45 0.04
47 INT185388 Binding of PVRL1 and TLR2 1 0.15 0.75 0.04
48 INT305383 Binding of NKX2-5 and FLNA 1 0.10 0.7 0.04
49 INT213206 ASAP2 Negative_regulation of PVR 1 0.01 0.44 0.04
50 INT213585 Binding of CFTR and FLNA 1 0.14 0.11 0.03
51 INT298450 Binding of CDH1 and Efs 1 0.03 0.96 0
52 INT269585 MAPKAP1 Negative_regulation of Phosphorylation of ACTN1 1 0.00 0 0
53 INT355603 Binding of CTNNA1 and Ctnnb1 1 0.00 1.07 0
54 INT197761 Binding of KRT5 and C4a 1 0.02 2.29 0
55 INT205046 MUC13 Negative_regulation of Localization of COL17A1 1 0.31 0.62 0
56 INT355588 Binding of CDH1 and CTNNA1 1 0.00 1.12 0
57 INT175624 Gene_expression of CDH2 Positive_regulation of CDH1 1 0.00 1.12 0
58 INT255164 Regulation of PM20D2 Regulation of FLNA 1 0.00 0.82 0
59 INT315069 ITGB4 Regulation of MT1X 1 0.27 0.52 0
60 INT197762 Binding of KRT5 and Cpe 1 0.19 1.14 0
61 INT256210 NPPB Regulation of PVR 1 0.24 1.14 0
62 INT261734 COL5A2 Regulation of Gene_expression of ACTB 1 0.17 0 0
63 INT287891 Binding of CDH1 and KRT20 1 0.00 0.5 0
64 INT249192 Binding of ACTN1 and S100A9 1 0.01 0 0
65 INT255165 PM20D2 Regulation of FLNA 1 0.00 0.76 0
66 INT266555 Mapk8 Regulation of JUP 1 0.08 0.1 0
67 INT303090 Akt1 Negative_regulation of CADM1 1 0.14 0.29 0
68 INT303469 CDH3 Negative_regulation of Dpyd 1 0.01 0 0
69 INT269213 Binding of SNAI1 and Positive_regulation of Gene_expression of CDH1 1 0.37 1.03 0
70 INT256209 AVP Regulation of PVR 1 0.06 0.99 0
71 INT337407 MIR200A Positive_regulation of CDH1 1 0.00 0.29 0
72 INT315071 ITGB4 Regulation of Gene_expression of PAR4 1 0.35 0.53 0
73 INT303087 Akt1 Negative_regulation of Gene_expression of CADM1 1 0.14 0.29 0
74 INT255163 Binding of FLNA and PM20D2 1 0.00 0 0
75 INT205056 LGALS4 Negative_regulation of Localization of COL17A1 1 0.32 0.62 0
76 INT147062 LAMC2 Negative_regulation of CD40LG 1 0.47 0 0
77 INT249186 Binding of ACTN1 and S100A8 1 0.01 0 0
78 INT298438 Binding of CDH1 and SNAI1 1 0.14 1.16 0
79 INT347297 ILK Regulation of Gene_expression of AKT1 1 0.21 0.62 0
80 INT232594 CDH1 Regulation of HEPACAM 1 0.01 1.02 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for cell junction assembly. They are ordered first by their pain relevance and then by number of times they were reported in cell junction assembly. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT10847 Gene_expression of LAMC2 39 0.75 27 12.09
2 INT68373 Negative_regulation of FLNA 59 0.57 60.46 9.55
3 INT22481 Gene_expression of CADM1 28 0.65 30.26 8.5
4 INT111607 Gene_expression of CDH1 103 0.75 90.45 7.77
5 INT25 Positive_regulation of LAMC2 19 0.67 8.64 7.06
6 INT19768 Negative_regulation of LAMC2 11 0.57 10.54 5.32
7 INT113948 Gene_expression of FLNA 32 0.73 36.06 4.81
8 INT94453 Gene_expression of ITGB1 50 0.75 18.41 4.72
9 INT39948 Binding of FLNA 45 0.42 58.05 4.27
10 INT63880 Positive_regulation of FLNA 29 0.59 13.88 3.97
11 INT61680 Positive_regulation of PVR 23 0.60 23.27 3.86
12 INT639 Regulation of LAMC2 8 0.44 4.68 2.92
13 INT10851 Negative_regulation of Gene_expression of LAMC2 2 0.57 2.54 2.68
14 INT99550 Regulation of FLNA 51 0.54 27.88 2.58
15 INT66002 Binding of LAMC2 9 0.47 4.5 2.54
16 INT46646 Localization of FLNA 19 0.73 18.83 2.53
17 INT193582 Gene_expression of PVR 21 0.58 14 2.39
18 INT73335 Gene_expression of ACTB 21 0.58 5.62 1.94
19 INT22482 Negative_regulation of Gene_expression of CADM1 6 0.49 3.2 1.8
20 INT98580 Positive_regulation of CADM1 11 0.49 10.16 1.78
21 INT111603 Positive_regulation of Gene_expression of CDH1 14 0.49 11.17 1.72
22 INT57973 Positive_regulation of ITGB1 5 0.67 1.23 1.44
23 INT139237 Negative_regulation of Gene_expression of CDH1 23 0.57 24.31 1.28
24 INT185396 Gene_expression of PVRL1 17 0.34 15.18 1.18
25 INT98595 Regulation of ILK 6 0.62 3.84 1.16
26 INT157765 Negative_regulation of CDH1 32 0.53 35.72 1.15
27 INT111605 Positive_regulation of CDH1 12 0.50 7.95 1.15
28 INT227925 Negative_regulation of Gene_expression of ITGB1 1 0.02 2.19 1.12
29 INT28929 Negative_regulation of PVR 22 0.57 16.64 1.07
30 INT151689 Positive_regulation of Gene_expression of CADM1 6 0.08 4.31 1.02
31 INT242171 Protein_catabolism of JUP 4 0.96 0.91 1.01
32 INT129971 Regulation of PVR 5 0.60 3.96 0.97
33 INT71917 Gene_expression of ACTN1 4 0.24 2.27 0.96
34 INT142423 Negative_regulation of Positive_regulation of FLNA 2 0.05 0.99 0.89
35 INT10855 Positive_regulation of Gene_expression of LAMC2 4 0.67 2.05 0.88
36 INT113672 Positive_regulation of Gene_expression of ITGB1 3 0.49 1.4 0.86
37 INT28774 Localization of LAMC2 6 0.73 3.2 0.76
38 INT171585 Positive_regulation of INADL 3 0.40 0.61 0.75
39 INT153565 Gene_expression of PRKCI 1 0.75 0 0.72
40 INT86370 Regulation of CDH1 10 0.54 13.89 0.7
41 INT44092 Binding of ACTN1 7 0.20 1.52 0.62
42 INT153568 Binding of PRKCI 1 0.36 0 0.6
43 INT341563 Positive_regulation of ITGB4 1 0.38 2.58 0.59
44 INT282645 Binding of CADM1 1 0.14 3.32 0.58
45 INT111601 Negative_regulation of Gene_expression of CTNNA1 1 0.24 0.58 0.58
46 INT111609 Gene_expression of CTNNA1 3 0.46 3.2 0.57
47 INT159190 Gene_expression of KRT5 31 0.65 26.67 0.56
48 INT98590 Negative_regulation of Positive_regulation of ILK 1 0.43 1.17 0.55
49 INT98592 Gene_expression of ILK 6 0.78 5.23 0.53
50 INT145225 Transcription of ITGB1 1 0.10 0.1 0.52
51 INT155214 Negative_regulation of ACTN1 1 0.28 0.16 0.51
52 INT266535 Phosphorylation of JUP 3 0.79 0.63 0.49
53 INT98594 Positive_regulation of ILK 3 0.70 1.74 0.49
54 INT278079 Positive_regulation of Positive_regulation of PVR 1 0.17 2.24 0.49
55 INT124990 Regulation of Gene_expression of CADM1 3 0.01 1.89 0.48
56 INT124991 Regulation of CADM1 2 0.01 1.67 0.47
57 INT111606 Positive_regulation of CTNNA1 1 0.12 0.47 0.47
58 INT242168 Transcription of JUP 4 0.67 1.17 0.46
59 INT185393 Regulation of PVRL1 4 0.24 1.48 0.45
60 INT188173 Gene_expression of CDH5 14 0.49 3.17 0.44
61 INT307766 Negative_regulation of CADM1 1 0.02 2.13 0.44
62 INT113949 Positive_regulation of Gene_expression of FLNA 2 0.44 0.34 0.39
63 INT214618 Transcription of FLNA 4 0.51 8.06 0.37
64 INT155215 Regulation of ACTN1 1 0.30 0.17 0.37
65 INT163489 Binding of CDH1 13 0.19 8.63 0.35
66 INT127871 Regulation of Gene_expression of CDH1 4 0.44 2.34 0.34
67 INT10853 Transcription of LAMC2 2 0.52 0.52 0.34
68 INT242169 Positive_regulation of Protein_catabolism of JUP 1 0.49 0.23 0.34
69 INT185401 Regulation of Gene_expression of PVRL1 1 0.27 4.69 0.34
70 INT119073 Negative_regulation of ITGB1 1 0.01 0.1 0.33
71 INT185886 Gene_expression of JUP 20 0.75 15.41 0.32
72 INT68338 Gene_expression of PLEC 4 0.75 0.44 0.32
73 INT82066 Gene_expression of COL17A1 1 0.74 1.83 0.3
74 INT98593 Positive_regulation of Positive_regulation of ILK 1 0.50 0.58 0.28
75 INT156901 Regulation of ACTB 8 0.28 3.76 0.26
76 INT158936 Gene_expression of CDH3 3 0.65 1.61 0.26
77 INT98579 Positive_regulation of Positive_regulation of CADM1 2 0.01 2.08 0.26
78 INT178106 Phosphorylation of PXN 2 0.12 1.14 0.25
79 INT98597 Positive_regulation of Gene_expression of ILK 4 0.70 3.08 0.23
80 INT24 Negative_regulation of Positive_regulation of LAMC2 1 0.42 0.55 0.21
81 INT173653 Positive_regulation of CDH2 3 0.06 1.77 0.18
82 INT134059 Negative_regulation of Negative_regulation of FLNA 1 0.02 0.38 0.18
83 INT269610 Phosphorylation of ACTN1 1 0.03 0.19 0.18
84 INT98591 Positive_regulation of Regulation of ILK 1 0.47 0.7 0.18
85 INT254701 Transcription of CDH1 6 0.67 2.5 0.17
86 INT151742 Positive_regulation of PLEC 3 0.41 0.89 0.17
87 INT189311 Gene_expression of ITGB4 2 0.41 0.53 0.16
88 INT141757 Negative_regulation of Positive_regulation of CADM1 1 0.01 1.22 0.16
89 INT277989 Positive_regulation of CDH5 3 0.11 1.66 0.15
90 INT82067 Positive_regulation of Gene_expression of COL17A1 1 0.66 0.91 0.15
91 INT164160 Localization of CDH1 8 0.66 3.39 0.14
92 INT44093 Positive_regulation of ACTN1 3 0.24 0 0.14
93 INT223937 Transcription of PVR 1 0.60 1.53 0.14
94 INT205083 Positive_regulation of JUP 6 0.49 5.51 0.13
95 INT211827 Localization of PVR 3 0.61 1.33 0.13
96 INT213211 Regulation of Localization of PVR 1 0.23 0.78 0.13
97 INT254136 Regulation of PLEC 1 0.23 0.33 0.13
98 INT230645 Binding of PLEC 3 0.47 0.8 0.12
99 INT222042 Localization of ITGB1 3 0.29 0.72 0.12
100 INT304610 Positive_regulation of Localization of FLNA 1 0.09 0.98 0.12
101 INT22718 Protein_catabolism of LAMC2 1 0.96 0 0.12
102 INT354691 Gene_expression of INADL 1 0.65 0.12 0.11
103 INT229402 Positive_regulation of PARD3 1 0.11 0.8 0.11
104 INT354690 Positive_regulation of Gene_expression of INADL 1 0.49 0.12 0.11
105 INT177991 Regulation of PXN 2 0.04 0.56 0.1
106 INT185394 Binding of PVRL1 5 0.14 2.94 0.09
107 INT54026 Transcription of ACTB 2 0.45 0.72 0.09
108 INT242173 Positive_regulation of Gene_expression of JUP 2 0.49 2.37 0.09
109 INT137828 Negative_regulation of Gene_expression of ACTB 1 0.13 0.33 0.09
110 INT70450 Binding of KRT5 6 0.47 5.72 0.08
111 INT309877 Localization of JUP 2 0.73 1.38 0.08
112 INT339206 Negative_regulation of Localization of JUP 1 0.41 1.1 0.08
113 INT159192 Negative_regulation of KRT5 1 0.42 0.58 0.08
114 INT159857 Positive_regulation of Binding of ACTN1 1 0.08 0.16 0.08
115 INT305385 Negative_regulation of Localization of FLNA 1 0.16 0.79 0.08
116 INT185395 Regulation of Regulation of PVRL1 1 0.17 0.53 0.08
117 INT188176 Positive_regulation of Gene_expression of CDH5 3 0.32 0.75 0.07
118 INT82068 Negative_regulation of Gene_expression of COL17A1 1 0.41 0.41 0.07
119 INT159859 Regulation of Binding of ACTN1 1 0.04 0.16 0.07
120 INT209184 Regulation of PRKCI 1 0.02 0.06 0.06
121 INT134674 Transcription of PLEC 1 0.49 0.41 0.06
122 INT269223 Positive_regulation of Localization of CDH1 1 0.38 0.84 0.06
123 INT225726 Positive_regulation of PXN 1 0.05 0.34 0.06
124 INT263800 Positive_regulation of Gene_expression of PVRL1 1 0.22 1.14 0.05
125 INT171951 Localization of CADM1 1 0.11 1.45 0.05
126 INT178278 Regulation of Positive_regulation of FLNA 1 0.04 0.4 0.05
127 INT201818 Regulation of CDH2 3 0.09 1.89 0.04
128 INT232991 Localization of KRT5 1 0.33 1.36 0.04
129 INT341556 Binding of ITGB4 1 0.18 0 0.04
130 INT269625 Positive_regulation of Phosphorylation of ACTN1 1 0.02 0.08 0.04
131 INT314241 Transcription of CDH5 1 0.31 0.07 0.04
132 INT211830 Binding of PVR 3 0.32 2.26 0.03
133 INT317004 Regulation of Phosphorylation of PLEC 1 0.37 0.06 0.03
134 INT317003 Phosphorylation of PLEC 1 0.67 0.06 0.03
135 INT287933 Negative_regulation of Binding of CDH1 1 0.03 0.65 0.03
136 INT175651 Gene_expression of CDH2 5 0.36 2.59 0
137 INT278829 Positive_regulation of Gene_expression of PVR 4 0.40 1.51 0
138 INT201814 Negative_regulation of CDH2 4 0.20 0.25 0
139 INT156900 Positive_regulation of ACTB 3 0.47 0.19 0
140 INT287949 Positive_regulation of Positive_regulation of CDH1 3 0.06 1.4 0
141 INT266537 Positive_regulation of Phosphorylation of JUP 2 0.49 0.29 0
142 INT269710 Negative_regulation of CDH3 2 0.08 0 0
143 INT266534 Negative_regulation of Phosphorylation of JUP 2 0.41 0.15 0
144 INT242174 Negative_regulation of Gene_expression of JUP 2 0.41 2.58 0
145 INT221864 Binding of JUP 2 0.36 1.05 0
146 INT263281 Negative_regulation of Transcription of CDH1 2 0.41 1.84 0
147 INT298446 Negative_regulation of Negative_regulation of CDH1 1 0.15 0.59 0
148 INT142317 Binding of CDH3 1 0.36 0.08 0
149 INT173646 Binding of CDH2 1 0.05 0.23 0
150 INT300908 Binding of ACTB 1 0.13 0.7 0
151 INT309874 Positive_regulation of Binding of JUP 1 0.49 0.32 0
152 INT350778 Regulation of Binding of CDH1 1 0.02 0.29 0
153 INT351556 Gene_expression of CDH4 1 0.50 0.08 0
154 INT174771 Negative_regulation of INADL 1 0.04 0 0
155 INT347313 Binding of ILK 1 0.22 0.12 0
156 INT201811 Negative_regulation of Gene_expression of CDH2 1 0.12 0.09 0
157 INT205090 Localization of COL17A1 1 0.57 0.61 0
158 INT242170 Negative_regulation of JUP 1 0.42 0.85 0
159 INT287950 Negative_regulation of Positive_regulation of CDH1 1 0.03 0.56 0
160 INT259156 Protein_catabolism of CDH1 1 0.16 0.38 0
161 INT346315 Negative_regulation of Regulation of CDH1 1 0.04 0.47 0
162 INT347317 Localization of ILK 1 0.45 0 0
163 INT308254 Negative_regulation of Binding of PVRL1 1 0.01 1.02 0
164 INT255171 Negative_regulation of Binding of FLNA 1 0.14 0.39 0
165 INT347314 Regulation of Gene_expression of ILK 1 0.27 1.15 0
166 INT300910 Regulation of Regulation of ACTB 1 0.11 0.72 0
167 INT232507 Regulation of CDH5 1 0.15 0.22 0
168 INT291604 Binding of ITGB1 1 0.05 0.16 0
169 INT214620 Regulation of Localization of FLNA 1 0.02 0.46 0
170 INT355598 Negative_regulation of CTNNA1 1 0.04 1.06 0
171 INT185402 Negative_regulation of Gene_expression of PVRL1 1 0.17 1.11 0
172 INT347307 Regulation of Binding of ILK 1 0.27 0.12 0
173 INT208570 Positive_regulation of Gene_expression of ACTB 1 0.35 0.19 0
174 INT160271 Positive_regulation of Localization of LAMC2 1 0.49 0.07 0
175 INT205097 Binding of COL17A1 1 0.28 0.63 0
176 INT331681 Regulation of Positive_regulation of PVR 1 0.36 0.57 0
177 INT309876 Regulation of JUP 1 0.60 0.67 0
178 INT356245 Transcription of CADM1 1 0.52 0.1 0
179 INT315097 Localization of ITGB4 1 0.51 0.26 0
180 INT254053 Gene_expression of CDH6 1 0.02 1.48 0
181 INT269224 Regulation of Transcription of CDH1 1 0.20 0.86 0
182 INT201805 Negative_regulation of Negative_regulation of CDH2 1 0.09 0.25 0
183 INT232960 Negative_regulation of Binding of KRT5 1 0.20 1.68 0
184 INT232946 Positive_regulation of Gene_expression of KRT5 1 0.23 0.33 0
185 INT232969 Positive_regulation of KRT5 1 0.27 1.24 0
186 INT214621 Regulation of Gene_expression of FLNA 1 0.02 1.09 0
187 INT309875 Regulation of Gene_expression of JUP 1 0.44 0.39 0
188 INT315126 Localization of ACTB 1 0.47 0.2 0
189 INT269658 Negative_regulation of Phosphorylation of ACTN1 1 0.02 0.11 0
190 INT175643 Positive_regulation of Gene_expression of CDH2 1 0.04 1.11 0
191 INT337474 Positive_regulation of Binding of CDH1 1 0.07 0.54 0
192 INT175647 Regulation of Gene_expression of ITGB1 1 0.01 0.4 0
193 INT188174 Negative_regulation of Gene_expression of CDH5 1 0.27 0 0
194 INT355092 Positive_regulation of Transcription of JUP 1 0.49 0.05 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox