GO:0034361

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Name very-low-density lipoprotein particle
Categary Component
Go Slim No
Go Link GO:0034361
Unique Molecular Interactions 277
Total Molecular Interactions 407
Total Single Events 2533
Pain Genes Associated 30

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for very-low-density lipoprotein particle. They are ordered first by their pain relevance and then by number of times they were reported for very-low-density lipoprotein particle. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT297332 Apoe Negative_regulation of Gene_expression of Mpz 1 0.02 1.09 0.87
2 INT208354 Binding of Apoe and Hdl1 12 0.13 8.37 0.77
3 INT147913 Phosphorylation of Camk2a Positive_regulation of Binding of Lpl 1 0.10 0 0.77
4 INT335054 LPL Positive_regulation of Localization of VLDLR 1 0.04 1.48 0.67
5 INT297344 Apoe Regulation of Binding of Alms1 1 0.08 1.1 0.61
6 INT297340 Apoe Regulation of Binding of Smo 1 0.10 1.1 0.6
7 INT297331 Apoe Negative_regulation of Gene_expression of Il6 1 0.14 0.61 0.57
8 INT254761 Igh-Dex Positive_regulation of Apoe 1 0.00 0.08 0.52
9 INT116862 Apoe Positive_regulation of Il10 1 0.30 0.69 0.5
10 INT116863 Apoe Negative_regulation of Hand1 1 0.37 0.69 0.5
11 INT254768 DNMT1 Positive_regulation of Gene_expression of Apoe 1 0.02 0.05 0.49
12 INT197496 Binding of Apoe and Lrp1 4 0.22 2.32 0.46
13 INT307781 Apoa1 Positive_regulation of LCAT 1 0.76 1.19 0.45
14 INT142608 Apoe Regulation of Gene_expression of Il6 1 0.25 1.01 0.44
15 INT213027 Binding of Apoa1 and Scarb1 6 0.09 7.52 0.43
16 INT307780 Apoa1 Positive_regulation of Soat1 1 0.04 1.14 0.42
17 INT254760 Igh-Dex Positive_regulation of Gene_expression of Apoe 1 0.00 0 0.42
18 INT329085 Csf2 Positive_regulation of Apoe 1 0.00 1.23 0.42
19 INT216881 Binding of Apoc4 and Hmox1 1 0.01 1.78 0.4
20 INT240617 Binding of APOB and ADIPOQ 1 0.04 3.62 0.38
21 INT274531 Il6 Regulation of Localization of Lpl 1 0.04 1.49 0.33
22 INT274530 Il6 Regulation of Lpl 1 0.07 1.48 0.32
23 INT253576 Binding of Lpl and Sp3 1 0.22 0.85 0.32
24 INT297335 Binding of Apoc3 and Hdl1 1 0.00 0.92 0.29
25 INT254759 Igh-Dex Positive_regulation of Localization of Apoe 1 0.00 0.32 0.28
26 INT254769 Binding of LDLR and Apoe 1 0.03 0 0.28
27 INT297338 Apoe Regulation of Gnb5 1 0.06 1.12 0.27
28 INT213029 Positive_regulation of Binding of Apoa1 and Scarb1 1 0.09 3.38 0.27
29 INT141635 Binding of APOB and Alb 1 0.02 0.3 0.26
30 INT350835 Binding of SELS and Sels 1 0.16 1.24 0.26
31 INT216880 Apoc4 Positive_regulation of Hmox1 1 0.03 1.06 0.25
32 INT307207 Ppara Positive_regulation of Apoa2 1 0.10 0.94 0.25
33 INT254772 DNMT1 Positive_regulation of Apoe 1 0.02 0 0.25
34 INT78293 Binding of Apoe and Ldlr 1 0.20 0.25 0.24
35 INT78295 Binding of Ptpra and Apoe 1 0.42 0.25 0.24
36 INT297334 Gnb5 Regulation of Apoe 1 0.09 0.83 0.24
37 INT78294 Negative_regulation of Binding of Ptpra and Apoe 1 0.48 0.25 0.24
38 INT254773 PPARA Positive_regulation of Gene_expression of Apoe 1 0.01 0.07 0.24
39 INT78292 Negative_regulation of Binding of Apoe and Ldlr 1 0.23 0.25 0.24
40 INT305798 Binding of APOA1 and OxP-11D 1 0.02 0.45 0.23
41 INT254774 DNMT1 Positive_regulation of Localization of Apoe 1 0.01 0.31 0.23
42 INT283857 APOA5 Positive_regulation of Positive_regulation of MAPK1 1 0.00 0.6 0.22
43 INT253568 Negative_regulation of Binding of Lpl and Sp3 1 0.19 0.37 0.22
44 INT216883 Apoc4 Positive_regulation of TFAM 1 0.00 0.93 0.22
45 INT249759 Positive_regulation of Cnr1 Positive_regulation of Lpl 1 0.29 0.74 0.21
46 INT283858 Binding of PTK2 and APOA5 1 0.00 0.67 0.21
47 INT283860 APOA5 Negative_regulation of MAPK1 1 0.00 0.59 0.21
48 INT189321 Binding of Apoa1 and Hdlcl1 1 0.00 0.68 0.2
49 INT134494 Binding of APOE and Alb 1 0.11 0.45 0.2
50 INT335053 PPARA Positive_regulation of Gene_expression of LPL 1 0.21 0.34 0.19
51 INT300193 Binding of APOA1 and INSL4 1 0.01 2.17 0.18
52 INT208360 Binding of Abca1 and Apoe 1 0.15 0.74 0.17
53 INT197499 Binding of Apoe and Tfrc 1 0.14 1.54 0.17
54 INT122528 Apoe Regulation of Eno2 1 0.05 0.29 0.16
55 INT122529 Apoe Regulation of S100B 1 0.18 0.29 0.16
56 INT43510 Apoa2 Positive_regulation of Localization of POMC 1 0.03 0 0.16
57 INT297345 Apoe Negative_regulation of Csf2 1 0.17 0.66 0.16
58 INT329850 APOA5 Negative_regulation of Transcription of APOC3 1 0.24 0.85 0.15
59 INT87110 Apom Negative_regulation of Pde1a 1 0.00 0 0.15
60 INT253564 Binding of Lpl and Sp1 1 0.13 0.9 0.14
61 INT297333 Apoe Negative_regulation of Positive_regulation of Tlr4 1 0.10 1.02 0.14
62 INT297343 Binding of Apoe and Tlr4 1 0.09 0.94 0.14
63 INT297339 Tlr4 Negative_regulation of Gene_expression of Apoe 1 0.10 0.73 0.13
64 INT21620 Binding of Ttpa and Vldlr 1 0.22 0.27 0.12
65 INT33752 Apoa2 Regulation of Localization of POMC 1 0.06 0 0.12
66 INT33750 Apoa2 Regulation of Agt 1 0.07 0 0.12
67 INT149792 Binding of Reln and Vldlr 3 0.51 0.35 0.11
68 INT33751 Apoa2 Positive_regulation of Positive_regulation of POMC 1 0.09 0 0.11
69 INT2458 Apoa2 Positive_regulation of Localization of Avp 1 0.10 0 0.11
70 INT213042 Apoa1 Positive_regulation of Nos3 1 0.10 2.17 0.11
71 INT298828 Binding of PPARA and Lpl 1 0.05 0.77 0.11
72 INT208361 Positive_regulation of Binding of Apoe and Hdl1 1 0.12 1.22 0.1
73 INT303990 Binding of Lep and Positive_regulation of Gene_expression of LPL 1 0.03 0.35 0.1
74 INT350820 INS Regulation of SELS 1 0.13 1.11 0.1
75 INT297346 Apoe Negative_regulation of Localization of TNF 1 0.48 0.26 0.1
76 INT305780 Binding of APOA1 and LRCH2 1 0.00 0.19 0.1
77 INT165619 Binding of LPL and TGS1 1 0.04 0.61 0.09
78 INT282094 Apoa2 Negative_regulation of BCL2 1 0.06 1.15 0.09
79 INT308585 Binding of APOB and PLA2G7 1 0.07 0.69 0.09
80 INT253571 Positive_regulation of Binding of Lpl and Sp1 1 0.17 0.42 0.09
81 INT253579 Negative_regulation of Binding of Lpl and Sp1 1 0.15 0.42 0.09
82 INT300192 Gene_expression of APOA1 Positive_regulation of HSD11B1 1 0.16 1.08 0.08
83 INT205135 Binding of APOE and APP 1 0.05 0.35 0.08
84 INT208362 Binding of Apoc4 and Hdl1 1 0.00 2.4 0.08
85 INT43121 Apoa2 Regulation of Smc1b 1 0.02 0 0.08
86 INT300641 Binding of APOE and CRP 1 0.41 0.81 0.07
87 INT297330 Apoe Positive_regulation of Gene_expression of Nos2 1 0.26 0.34 0.07
88 INT190885 Binding of Apoa2 and Hdl1 1 0.02 0.73 0.07
89 INT308665 Binding of Apoe and Gopc 1 0.02 0.49 0.07
90 INT308663 Apoe Regulation of Car2 1 0.02 0.44 0.07
91 INT279652 PPARA Positive_regulation of Gene_expression of Apoa1 1 0.00 0.75 0.07
92 INT50078 Binding of APOE and NPPA 1 0.30 0.42 0.07
93 INT326067 APOA1 Positive_regulation of Localization of APOE 1 0.61 4.22 0.07
94 INT335047 PPARA Positive_regulation of Gene_expression of APOA1 1 0.20 0.42 0.05
95 INT341019 Binding of VLDLR and Reln 1 0.01 0.1 0.05
96 INT253586 IFN1@ Negative_regulation of Transcription of Lpl 1 0.28 0 0.05
97 INT239348 Binding of Apoa1 and Hdl1 1 0.03 3.34 0.05
98 INT350823 Binding of SAA1 and SELS 1 0.17 2.75 0.05
99 INT296023 Positive_regulation of Apoa2 Negative_regulation of APOA1 1 0.50 0.35 0.05
100 INT296024 Apoa2 Negative_regulation of CETP 1 0.39 0.35 0.05
101 INT251468 Binding of APOE and DBT 1 0.03 1.18 0.05
102 INT43124 Apoa2 Positive_regulation of Positive_regulation of NA 1 0.07 0 0.05
103 INT340925 VLDLR Positive_regulation of Phosphorylation of DAB1 1 0.01 0.1 0.05
104 INT296025 Apoa2 Negative_regulation of APOA1 1 0.47 0.35 0.05
105 INT208353 Binding of Apoc4 and Apoc3 1 0.00 2.56 0.04
106 INT231395 Binding of HSD11B1 and Apob 1 0.27 1.18 0.04
107 INT236722 Ppara Positive_regulation of Binding of Apoa1 1 0.10 0.18 0.04
108 INT325027 Apoc3 Negative_regulation of Pnlip 1 0.01 1.02 0.04
109 INT208356 Hdl1 Positive_regulation of Apoe 1 0.12 1.25 0.04
110 INT293899 UPF1 Positive_regulation of Gene_expression of APOB 1 0.01 0 0.04
111 INT198922 Lrp8 Negative_regulation of Binding of Vldlr 1 0.19 0 0.04
112 INT235551 Gene_expression of Hras1 Negative_regulation of Positive_regulation of Apoe 1 0.03 0.57 0.04
113 INT240623 Binding of CRP and Apob 1 0.01 0.52 0.04
114 INT149794 Binding of LRP8 and Vldlr 1 0.02 0.17 0.04
115 INT290180 Binding of APOB and PLTP 1 0.19 0.6 0.04
116 INT208357 Hdl1 Positive_regulation of Localization of Apoe 1 0.12 1.26 0.04
117 INT325026 Apoc3 Negative_regulation of Lpl 1 0.03 1.01 0.04
118 INT288908 Apoa1 Positive_regulation of Gene_expression of HSD11B1 1 0.03 0.53 0.04
119 INT325025 Apoa2 Positive_regulation of Hdl1 1 0.05 1.03 0.04
120 INT208350 Positive_regulation of Hdl1 Positive_regulation of Apoe 1 0.12 1.27 0.04
121 INT198930 Binding of Lrp8 and Vldlr 1 0.16 0 0.04
122 INT290181 Binding of APOE and PLTP 1 0.17 1.61 0.04
123 INT247439 Binding of APOA1 and HSD11B1 3 0.32 5.01 0.03
124 INT257513 Regulation of Binding of Slc4a4 and H47 1 0.00 0.08 0.03
125 INT194483 Binding of Apoe and Chol1 1 0.24 0.51 0.03
126 INT257512 Binding of Slc4a4 and H47 1 0.00 0.08 0.03
127 INT253574 Sp3 Positive_regulation of Lpl 1 0.22 0 0.03
128 INT208352 Apoe Regulation of Localization of Em 1 0.04 1.15 0.03
129 INT194481 Binding of Apoe and Apob 1 0.07 0.51 0.03
130 INT239345 Apoa1 Positive_regulation of RCT 1 0.02 1.15 0.03
131 INT308658 Binding of Apoa2 and Apoe 1 0.17 0.15 0.03
132 INT194486 Binding of SNRNP70 and Apob 1 0.00 0.64 0.03
133 INT253566 Sp1 Positive_regulation of Lpl 1 0.18 0 0.03
134 INT332978 ACOX1 Negative_regulation of Transcription of Apoc3 1 0.00 0.98 0
135 INT247435 Binding of APOB and SNRNP70 1 0.04 2.2 0
136 INT353795 Binding of Cd320 and Apob 1 0.08 0.82 0
137 INT341015 VLDLR Positive_regulation of Lrp8 1 0.02 0.06 0
138 INT171598 Binding of APOB and Lipg 1 0.01 0.63 0
139 INT341487 Binding of APOE and TLR2 1 0.00 0.3 0
140 INT10903 Apoa2 Positive_regulation of Nppb 1 0.08 0.17 0
141 INT239332 Hdl1 Positive_regulation of Gene_expression of Apoa1 1 0.04 0.84 0
142 INT247441 Binding of APOC3 and SNRNP70 1 0.04 0.26 0
143 INT332905 Binding of LPL and SNRNP70 1 0.01 1.34 0
144 INT297560 Binding of HSD11B1 and APOL1 1 0.04 0.88 0
145 INT326065 APOE Positive_regulation of LCAT 1 0.53 0.84 0
146 INT344266 Binding of APOH and CD40LG 1 0.04 0.31 0
147 INT352793 Binding of APOC1 and FGF21 1 0.01 2.76 0
148 INT214472 Binding of LPL and GPIHBP1 1 0.29 1.17 0
149 INT353798 Binding of Hdl1 and Apob 1 0.01 0.82 0
150 INT47454 ras Positive_regulation of Apoa2 1 0.12 0.21 0
151 INT209987 Binding of APOE and LDLR 1 0.24 0 0
152 INT247444 Binding of APOA1 and APOC3 1 0.28 0.39 0
153 INT208349 Regulation of Binding of Apoc3 and Apoe 1 0.01 0.38 0
154 INT171599 Binding of APOC3 and Sst1 1 0.01 0.68 0
155 INT10907 Apoa2 Positive_regulation of Localization of Nppb 1 0.09 0.23 0
156 INT213017 Apoa1 Negative_regulation of Positive_regulation of Gtf3a 1 0.00 1.16 0
157 INT170236 Lpl Regulation of HSD11B1 1 0.04 0.98 0
158 INT350822 SELS Positive_regulation of Gene_expression of SAA1 1 0.21 0.87 0
159 INT247436 Binding of APOA1 and SACM1L 1 0.27 0.39 0
160 INT90283 Binding of APOE and Il1a 1 0.01 0 0
161 INT290193 Binding of APOA1 and Hdl1 1 0.01 1 0
162 INT340929 VLDLR Positive_regulation of PIK3CB 1 0.01 0.06 0
163 INT208365 Apoc3 Positive_regulation of Localization of PROC 1 0.00 1.13 0
164 INT298849 Binding of APOB and MCC 1 0.00 0.38 0
165 INT201080 Binding of APOE and HLA-C 1 0.41 0.31 0
166 INT332962 Acaa1a Negative_regulation of Transcription of Apoc3 1 0.01 0.93 0
167 INT283865 Binding of MAPK1 and APOA5 1 0.00 0.22 0
168 INT353802 Binding of APOE and Apob 1 0.05 0.83 0
169 INT210417 APOB Negative_regulation of CYP2D6 1 0.01 0 0
170 INT211576 Vldlr Positive_regulation of Lpl 1 0.38 0.24 0
171 INT283866 Binding of SVIL and APOA5 1 0.00 0.22 0
172 INT208355 Binding of Apoc3 and Apoe 1 0.01 0.76 0
173 INT298856 Binding of APOB and MTG1 1 0.00 0.38 0
174 INT239353 CETP Regulation of Apoa1 1 0.16 0.65 0
175 INT171601 INCENP Negative_regulation of Lpl 1 0.01 0.38 0
176 INT302584 Binding of Lpl and Apoa5 1 0.20 0.63 0
177 INT198933 Binding of Apoe and App 1 0.33 0.19 0
178 INT239342 Lcat Regulation of Apoa1 1 0.16 0.65 0
179 INT250554 Binding of F5 and SELS 1 0.24 1.07 0
180 INT286444 PCSK9 Positive_regulation of Apob 1 0.02 0.49 0
181 INT277047 Binding of APOB and LDLR 1 0.25 0.82 0
182 INT353801 Binding of APOE and Cd320 1 0.22 0.83 0
183 INT341017 Binding of VLDLR and Lrp8 1 0.02 0 0
184 INT309889 Positive_regulation of CNR1 Positive_regulation of LPL 1 0.05 1.25 0
185 INT326060 Binding of ABCA1 and APOA1 1 0.39 1.5 0
186 INT344723 Niacr1 Positive_regulation of Binding of APOB 1 0.31 1.05 0
187 INT353796 Binding of Ldlr and Apob 1 0.06 0.82 0
188 INT250152 Binding of APOE and UBE4B 1 0.21 1.2 0
189 INT247438 Binding of APOB and SACM1L 1 0.28 2 0
190 INT326058 Negative_regulation of PRKCA Negative_regulation of APOA1 1 0.15 0.32 0
191 INT267974 APOB Negative_regulation of HSD11B1 1 0.01 0.75 0
192 INT326059 APOA1 Positive_regulation of Gene_expression of APOE 1 0.61 0.38 0
193 INT211577 Vldlr Regulation of Gene_expression of Lpin1 1 0.27 0.12 0
194 INT302594 Binding of CETP and Apoa5 1 0.26 0.63 0
195 INT326064 APOA1 Positive_regulation of HMGCR 1 0.16 0.19 0
196 INT213043 Regulation of Binding of Apoa1 and Scarb1 1 0.05 1.12 0
197 INT350824 INS Positive_regulation of Gene_expression of SELS 1 0.22 0.85 0
198 INT235960 Binding of Aqp4 and H47 1 0.01 0.13 0
199 INT180470 Cdh23 Positive_regulation of Lpl 1 0.06 1.23 0
200 INT340923 VLDLR Positive_regulation of DAB1 1 0.01 0.06 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for very-low-density lipoprotein particle. They are ordered first by their pain relevance and then by number of times they were reported in very-low-density lipoprotein particle. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT116861 Gene_expression of Apoe 182 0.78 100.41 27.26
2 INT8579 Gene_expression of Apoa1 13 0.76 35.89 7.21
3 INT197493 Localization of Apoe 61 0.79 27.48 7.06
4 INT142264 Positive_regulation of Apoe 47 0.50 26.35 6.94
5 INT19146 Negative_regulation of Apoa2 19 0.36 5.34 6.73
6 INT182351 Positive_regulation of Gene_expression of Apoe 38 0.50 19.78 6.72
7 INT63042 Binding of Apoe 59 0.48 31.23 5.88
8 INT74614 Positive_regulation of Apoa1 16 0.68 23.95 5.04
9 INT55758 Positive_regulation of Apoe 15 0.70 11.71 4.69
10 INT181886 Gene_expression of Apoa1 40 0.64 40.53 4.56
11 INT2453 Positive_regulation of Apoa2 20 0.54 3.49 4.08
12 INT28673 Gene_expression of APOB 51 0.73 34.02 3.95
13 INT15033 Gene_expression of Apoe 18 0.78 14.97 3.75
14 INT104624 Negative_regulation of Apoe 26 0.59 19.25 3.71
15 INT52047 Gene_expression of APOE 50 0.78 34.75 3.52
16 INT72141 Binding of Apoe 11 0.37 10.91 3.27
17 INT250581 Gene_expression of SELS 4 0.78 47.37 3.27
18 INT97710 Localization of Apoe 1 0.79 7.18 3.2
19 INT147907 Positive_regulation of Lpl 12 0.29 6.48 3.13
20 INT198888 Gene_expression of Apoc4 12 0.27 5.44 3.09
21 INT10830 Regulation of Apoa1 11 0.44 15.1 3.04
22 INT10556 Regulation of Apoa2 5 0.44 0.51 2.8
23 INT147900 Phosphorylation of Lpl 1 0.16 0 2.73
24 INT50080 Binding of APOE 38 0.45 29.61 2.67
25 INT21712 Positive_regulation of APOA1 32 0.67 21.64 2.64
26 INT97713 Negative_regulation of Apoe 4 0.59 4.57 2.52
27 INT1928 Negative_regulation of Lpl 18 0.51 11.22 2.49
28 INT181880 Positive_regulation of Apoa1 19 0.66 21.19 2.43
29 INT2452 Localization of Apoa2 9 0.55 0 2.3
30 INT208344 Positive_regulation of Localization of Apoe 22 0.48 9.6 2.27
31 INT142265 Regulation of Apoe 20 0.60 9.52 2.23
32 INT84060 Regulation of Apoe 4 0.62 3.33 2.05
33 INT45176 Negative_regulation of LPL 34 0.59 22.22 2.01
34 INT49313 Positive_regulation of Gene_expression of Apoa1 3 0.68 9.55 2.01
35 INT45838 Positive_regulation of LPL 15 0.69 11.33 2
36 INT190883 Gene_expression of Apoc3 16 0.38 14.18 1.93
37 INT40877 Positive_regulation of APOB 35 0.68 32.47 1.86
38 INT22863 Negative_regulation of Apoa1 10 0.57 10.68 1.86
39 INT147899 Binding of Lpl 6 0.30 2.07 1.82
40 INT7459 Positive_regulation of Lpl 15 0.70 6.96 1.81
41 INT21813 Gene_expression of Apoa2 10 0.61 3.68 1.81
42 INT72676 Gene_expression of APOA1 34 0.75 34.15 1.67
43 INT156484 Binding of Apoa1 4 0.47 6.78 1.63
44 INT96814 Negative_regulation of APOE 13 0.59 10.64 1.61
45 INT9466 Binding of APOB 27 0.41 19.36 1.56
46 INT147906 Positive_regulation of Phosphorylation of Lpl 1 0.13 0 1.5
47 INT181881 Positive_regulation of Gene_expression of Apoa1 13 0.48 14.31 1.45
48 INT217388 Negative_regulation of Gene_expression of Apoe 11 0.59 6.07 1.4
49 INT113960 Positive_regulation of Gene_expression of APOB 8 0.49 5.88 1.39
50 INT181882 Localization of Apoa1 8 0.71 7.94 1.37
51 INT37799 Gene_expression of Apob 13 0.56 10.59 1.36
52 INT97716 Transcription of Apoe 3 0.53 2.61 1.36
53 INT20238 Regulation of APOB 9 0.61 11.52 1.26
54 INT118817 Positive_regulation of Apoc4 6 0.45 6.44 1.23
55 INT97715 Regulation of Gene_expression of Apoe 3 0.62 1.98 1.23
56 INT113336 Positive_regulation of Gene_expression of Apoe 3 0.70 1.79 1.23
57 INT147909 Gene_expression of Lpl 21 0.58 9.35 1.14
58 INT181879 Negative_regulation of Apoa1 8 0.55 8.18 1.11
59 INT198879 Localization of Vldlr 6 0.39 0.58 1.1
60 INT38265 Gene_expression of LPL 22 0.78 10.59 1.09
61 INT217390 Negative_regulation of Positive_regulation of Apoe 3 0.37 1.95 1.05
62 INT97714 Negative_regulation of Localization of Apoe 1 0.58 1.83 0.97
63 INT10827 Gene_expression of Apob 16 0.78 13.08 0.9
64 INT180451 Positive_regulation of Apoa2 15 0.67 12.65 0.89
65 INT72672 Positive_regulation of Gene_expression of APOA1 4 0.67 3.81 0.89
66 INT9467 Negative_regulation of APOB 14 0.57 10.49 0.88
67 INT11949 Negative_regulation of Apob 11 0.09 8.13 0.85
68 INT95561 Negative_regulation of Vldlr 9 0.53 2.59 0.84
69 INT181885 Binding of Apoa1 7 0.35 5.66 0.84
70 INT10828 Regulation of Apob 7 0.39 7.55 0.83
71 INT142597 Regulation of Binding of Apoe 1 0.34 2.21 0.8
72 INT51739 Negative_regulation of Apob 9 0.42 4.21 0.78
73 INT147904 Negative_regulation of Binding of Lpl 1 0.08 0 0.78
74 INT147905 Negative_regulation of Phosphorylation of Lpl 1 0.11 0 0.74
75 INT197495 Negative_regulation of Localization of Apoe 6 0.43 2.19 0.73
76 INT44612 Positive_regulation of APOE 16 0.67 5.73 0.72
77 INT270428 Negative_regulation of Binding of APOE 2 0.41 1.16 0.7
78 INT113335 Regulation of Transcription of Apoe 1 0.27 0.51 0.7
79 INT25374 Negative_regulation of Negative_regulation of Apoa2 1 0.30 0.24 0.67
80 INT198899 Regulation of Localization of Vldlr 1 0.24 0.17 0.67
81 INT83194 Binding of APOH 4 0.17 3.92 0.66
82 INT335102 Positive_regulation of Positive_regulation of LPL 1 0.14 1.48 0.66
83 INT175580 Localization of APOE 10 0.76 18.84 0.65
84 INT97708 Regulation of Localization of Apoe 1 0.61 2.06 0.62
85 INT181888 Regulation of Apoa1 5 0.26 5.07 0.6
86 INT213118 Negative_regulation of Gene_expression of Apoa1 2 0.42 2.86 0.6
87 INT113334 Positive_regulation of Positive_regulation of Apoe 1 0.50 0.6 0.56
88 INT45839 Regulation of LPL 10 0.55 7.64 0.55
89 INT200980 Transcription of APOL1 1 0.67 0.84 0.54
90 INT201005 Gene_expression of APOL1 9 0.75 4.66 0.53
91 INT10983 Binding of Apoa2 7 0.45 4.21 0.52
92 INT20239 Regulation of APOA1 10 0.60 10.98 0.51
93 INT239247 Positive_regulation of APOA5 7 0.37 3.68 0.51
94 INT197322 Protein_catabolism of Apoe 6 0.71 3.52 0.51
95 INT8638 Regulation of Vldlr 3 0.44 1.57 0.51
96 INT235512 Transcription of Lpl 10 0.42 2.76 0.49
97 INT10862 Positive_regulation of Vldlr 4 0.15 2.96 0.49
98 INT217370 Phosphorylation of Apoe 2 0.63 1.8 0.49
99 INT15047 Negative_regulation of SELS 1 0.35 0.34 0.49
100 INT37800 Positive_regulation of Apob 7 0.18 11.01 0.48
101 INT43397 Positive_regulation of Localization of Apoa2 1 0.09 0 0.48
102 INT170208 Negative_regulation of Lpl 15 0.49 6.07 0.45
103 INT198884 Gene_expression of Vldlr 13 0.70 2.41 0.44
104 INT96816 Regulation of APOE 8 0.45 6.62 0.44
105 INT190882 Regulation of Gene_expression of Apoa1 4 0.23 3.67 0.43
106 INT133379 Negative_regulation of APOH 1 0.07 0.09 0.42
107 INT174753 Gene_expression of Apoa2 15 0.75 13.82 0.41
108 INT100254 Binding of SELS 6 0.36 4.54 0.4
109 INT335112 Regulation of Localization of APOC3 1 0.13 0.73 0.4
110 INT97712 Negative_regulation of Transcription of Apoe 1 0.43 1.05 0.4
111 INT335117 Localization of APOC3 1 0.40 0.73 0.4
112 INT190691 Negative_regulation of APOA1 12 0.42 15.9 0.39
113 INT181883 Negative_regulation of Negative_regulation of Apoa1 1 0.40 1.24 0.39
114 INT72673 Transcription of APOA1 2 0.52 1.2 0.36
115 INT81221 Positive_regulation of APOH 1 0.02 1.24 0.36
116 INT339386 Negative_regulation of Gene_expression of Apob 3 0.43 1.91 0.34
117 INT159311 Gene_expression of Vldlr 2 0.65 0.89 0.34
118 INT131542 Negative_regulation of Gene_expression of APOE 6 0.40 3.92 0.33
119 INT261209 Localization of Apoa1 4 0.73 2.61 0.33
120 INT335105 Localization of VLDLR 1 0.21 0.71 0.33
121 INT26173 Regulation of SELS 3 0.52 3.4 0.32
122 INT130344 Gene_expression of APOH 3 0.34 2.87 0.32
123 INT47453 Positive_regulation of Positive_regulation of Apoa2 3 0.31 1.17 0.32
124 INT274529 Localization of Lpl 2 0.46 2.31 0.32
125 INT350833 Positive_regulation of Gene_expression of SELS 1 0.61 6.07 0.32
126 INT307779 Positive_regulation of Localization of Apoa1 1 0.49 0.88 0.31
127 INT83352 Positive_regulation of Negative_regulation of APOB 1 0.01 0.69 0.31
128 INT83195 Regulation of Binding of APOH 1 0.13 0.88 0.31
129 INT189968 Binding of APOA1 12 0.47 10.1 0.3
130 INT208346 Binding of Apoc4 5 0.03 3.78 0.3
131 INT253540 Positive_regulation of Transcription of Lpl 3 0.29 1.43 0.3
132 INT190878 Positive_regulation of Gene_expression of Apoc3 3 0.29 2.76 0.3
133 INT311128 Positive_regulation of Regulation of Apoe 1 0.30 0.3 0.3
134 INT43396 Regulation of Localization of Apoa2 1 0.09 0 0.3
135 INT175687 Transcription of Apoe 4 0.72 2.12 0.29
136 INT96815 Regulation of Gene_expression of APOE 2 0.62 1.1 0.29
137 INT213281 Localization of LPL 3 0.21 3.48 0.28
138 INT113456 Binding of Lpl 2 0.36 0.81 0.28
139 INT10861 Negative_regulation of Vldlr 5 0.11 3.22 0.27
140 INT297322 Binding of Apoa2 3 0.36 1.7 0.27
141 INT97711 Positive_regulation of Transcription of Apoe 1 0.46 1.06 0.27
142 INT238864 Positive_regulation of Gene_expression of LPL 5 0.24 2.39 0.26
143 INT254756 Regulation of Positive_regulation of Apoe 1 0.20 0.22 0.26
144 INT200986 Positive_regulation of Gene_expression of APOL1 1 0.36 0.26 0.26
145 INT67227 Positive_regulation of Binding of Apoa2 2 0.26 1.31 0.25
146 INT350825 Gene_expression of Sels 1 0.34 1.07 0.25
147 INT2450 Negative_regulation of Positive_regulation of Apoa2 1 0.21 0 0.24
148 INT200997 Regulation of Transcription of APOL1 1 0.32 0.23 0.24
149 INT201019 Localization of APOL1 3 0.66 1.29 0.23
150 INT268222 Negative_regulation of Localization of Vldlr 1 0.02 0.26 0.23
151 INT247452 Gene_expression of APOA5 4 0.54 5.71 0.22
152 INT194472 Positive_regulation of Gene_expression of Apob 2 0.15 1.71 0.22
153 INT2449 Negative_regulation of Localization of Apoa2 1 0.19 0 0.22
154 INT283891 Positive_regulation of Gene_expression of APOA5 1 0.01 1.36 0.22
155 INT323964 Negative_regulation of Binding of Apoe 1 0.39 0.35 0.22
156 INT323965 Protein_catabolism of Apoa2 1 0.01 0.34 0.22
157 INT198892 Regulation of Binding of Apoe 6 0.45 2.94 0.21
158 INT305975 Regulation of Gene_expression of SELS 2 0.60 3.19 0.21
159 INT208337 Positive_regulation of Gene_expression of Apoc4 2 0.03 1.22 0.21
160 INT47256 Transcription of Lpl 2 0.69 0.26 0.21
161 INT47258 Regulation of Lpl 1 0.27 0.26 0.21
162 INT47257 Regulation of Transcription of Lpl 1 0.45 0.26 0.21
163 INT171597 Gene_expression of APOC3 9 0.77 3.18 0.2
164 INT180454 Negative_regulation of Apoa2 6 0.42 7.42 0.2
165 INT283877 Localization of APOA5 3 0.27 1.48 0.2
166 INT193810 Phosphorylation of APOE 2 0.27 1.13 0.2
167 INT75874 Positive_regulation of Regulation of Vldlr 1 0.11 0.42 0.2
168 INT190874 Negative_regulation of Gene_expression of Apoa1 1 0.15 0.9 0.2
169 INT335113 Negative_regulation of Gene_expression of APOC3 1 0.24 0.34 0.2
170 INT10984 Negative_regulation of Binding of Apoa2 2 0.35 0.7 0.19
171 INT203836 Negative_regulation of Negative_regulation of Apob 1 0.18 0.45 0.19
172 INT350827 Localization of SELS 1 0.62 1.24 0.19
173 INT212383 Gene_expression of VLDLR 4 0.28 1.19 0.18
174 INT208335 Binding of Apoc3 3 0.01 2.11 0.18
175 INT198874 Binding of Vldlr 3 0.32 0.73 0.18
176 INT239275 Regulation of Localization of Apoa1 1 0.19 1.62 0.18
177 INT190876 Negative_regulation of Apoc3 2 0.15 1.43 0.17
178 INT67225 Positive_regulation of Gene_expression of Apoa2 2 0.28 1.3 0.17
179 INT305978 Protein_catabolism of SELS 1 0.86 0.88 0.17
180 INT254754 Regulation of Localization of Apoe 1 0.20 0.39 0.17
181 INT100573 Gene_expression of Lpl 13 0.53 2.09 0.16
182 INT211546 Regulation of Lpl 6 0.26 1.71 0.16
183 INT62274 Negative_regulation of Gene_expression of APOB 4 0.32 5.9 0.16
184 INT277049 Regulation of Binding of APOB 1 0.27 0.91 0.16
185 INT198868 Regulation of Vldlr 1 0.14 0.73 0.16
186 INT254755 Positive_regulation of Transcription of Apoe 1 0.16 0.41 0.16
187 INT297577 Localization of APOA1 12 0.65 4.58 0.15
188 INT171595 Negative_regulation of APOC3 3 0.43 1.99 0.15
189 INT235518 Negative_regulation of Transcription of Lpl 2 0.34 1.35 0.15
190 INT171589 Transcription of APOC3 2 0.71 1.25 0.15
191 INT252219 Negative_regulation of Binding of Apoa1 1 0.16 0.95 0.15
192 INT200973 Negative_regulation of APOL1 1 0.14 0.18 0.15
193 INT96772 Positive_regulation of Gene_expression of APOE 5 0.66 5.44 0.14
194 INT198894 Regulation of Gene_expression of Apoe 2 0.44 0.56 0.14
195 INT126804 Gene_expression of APOC1 1 0.75 1.06 0.14
196 INT191137 Binding of H47 4 0.19 1.22 0.13
197 INT203827 Localization of Apob 3 0.32 1.81 0.13
198 INT190877 Regulation of Gene_expression of Apoc3 2 0.11 2.09 0.13
199 INT240040 Protein_catabolism of Apob 1 0.01 1.79 0.13
200 INT350834 Transcription of SELS 1 0.53 4.8 0.13
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