GO:0034362

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Name low-density lipoprotein particle
Categary Component
Go Slim No
Go Link GO:0034362
Unique Molecular Interactions 252
Total Molecular Interactions 349
Total Single Events 2822
Pain Genes Associated 18

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for low-density lipoprotein particle. They are ordered first by their pain relevance and then by number of times they were reported for low-density lipoprotein particle. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT153923 Msr1 Positive_regulation of Gene_expression of Tdo2 1 0.00 0.89 1.28
2 INT207437 Binding of PLA2G7 and ERAL1 1 0.14 3.64 1.11
3 INT297332 Apoe Negative_regulation of Gene_expression of Mpz 1 0.02 1.09 0.87
4 INT208354 Binding of Apoe and Hdl1 12 0.13 8.37 0.77
5 INT95560 Binding of Msr1 and Zfp940 1 0.00 0.24 0.66
6 INT297344 Apoe Regulation of Binding of Alms1 1 0.08 1.1 0.61
7 INT297340 Apoe Regulation of Binding of Smo 1 0.10 1.1 0.6
8 INT98725 Msr1 Positive_regulation of Gene_expression of Creb1 1 0.00 0.09 0.6
9 INT95559 Msr1 Negative_regulation of Binding of Zfp940 1 0.00 0.23 0.59
10 INT207440 Binding of HDLBP and PLA2G7 1 0.06 1.25 0.58
11 INT297331 Apoe Negative_regulation of Gene_expression of Il6 1 0.14 0.61 0.57
12 INT254761 Igh-Dex Positive_regulation of Apoe 1 0.00 0.08 0.52
13 INT334901 LDLR Positive_regulation of Crp 1 0.00 1.48 0.51
14 INT116862 Apoe Positive_regulation of Il10 1 0.30 0.69 0.5
15 INT116863 Apoe Negative_regulation of Hand1 1 0.37 0.69 0.5
16 INT254768 DNMT1 Positive_regulation of Gene_expression of Apoe 1 0.02 0.05 0.49
17 INT197496 Binding of Apoe and Lrp1 4 0.22 2.32 0.46
18 INT143619 Bhlhe22 Positive_regulation of Regulation of Msr1 1 0.40 0.93 0.46
19 INT142608 Apoe Regulation of Gene_expression of Il6 1 0.25 1.01 0.44
20 INT270043 Binding of Ldlr and Hdl1 1 0.01 2.3 0.43
21 INT98726 Binding of Msr1 and Tacr2 1 0.00 0.06 0.42
22 INT254760 Igh-Dex Positive_regulation of Gene_expression of Apoe 1 0.00 0 0.42
23 INT329085 Csf2 Positive_regulation of Apoe 1 0.00 1.23 0.42
24 INT240617 Binding of APOB and ADIPOQ 1 0.04 3.62 0.38
25 INT153924 Msr1 Regulation of Adrb3 1 0.02 0.24 0.32
26 INT207434 LPA Regulation of Gene_expression of PLA2G7 1 0.11 0.73 0.31
27 INT293203 MSR1 Regulation of Localization of IK 1 0.00 0.19 0.3
28 INT145284 Msr1 Negative_regulation of FEM1B 1 0.01 0 0.29
29 INT118545 Binding of Agtr2 and Msr1 1 0.00 0.09 0.29
30 INT145283 Msr1 Negative_regulation of Tac4 1 0.00 0 0.29
31 INT254759 Igh-Dex Positive_regulation of Localization of Apoe 1 0.00 0.32 0.28
32 INT207436 IL8 Negative_regulation of Gene_expression of PLA2G7 1 0.10 0.9 0.28
33 INT207442 IFNG Negative_regulation of Gene_expression of PLA2G7 1 0.08 0.9 0.28
34 INT254769 Binding of LDLR and Apoe 1 0.03 0 0.28
35 INT118546 Msr1 Negative_regulation of Gene_expression of CNR2 1 0.00 0.07 0.28
36 INT207435 IL1B Negative_regulation of Gene_expression of PLA2G7 1 0.07 0.9 0.28
37 INT297338 Apoe Regulation of Gnb5 1 0.06 1.12 0.27
38 INT141635 Binding of APOB and Alb 1 0.02 0.3 0.26
39 INT207441 Binding of LPA and PLA2G7 1 0.10 0.56 0.26
40 INT350835 Binding of SELS and Sels 1 0.16 1.24 0.26
41 INT254772 DNMT1 Positive_regulation of Apoe 1 0.02 0 0.25
42 INT78296 Negative_regulation of Binding of Ptpra and Ldlr 1 0.22 0.25 0.24
43 INT78293 Binding of Apoe and Ldlr 1 0.20 0.25 0.24
44 INT78295 Binding of Ptpra and Apoe 1 0.42 0.25 0.24
45 INT297334 Gnb5 Regulation of Apoe 1 0.09 0.83 0.24
46 INT78294 Negative_regulation of Binding of Ptpra and Apoe 1 0.48 0.25 0.24
47 INT254773 PPARA Positive_regulation of Gene_expression of Apoe 1 0.01 0.07 0.24
48 INT78292 Negative_regulation of Binding of Apoe and Ldlr 1 0.23 0.25 0.24
49 INT78291 Binding of Ptpra and Ldlr 1 0.20 0.25 0.24
50 INT254774 DNMT1 Positive_regulation of Localization of Apoe 1 0.01 0.31 0.23
51 INT283857 APOA5 Positive_regulation of Positive_regulation of MAPK1 1 0.00 0.6 0.22
52 INT283858 Binding of PTK2 and APOA5 1 0.00 0.67 0.21
53 INT283860 APOA5 Negative_regulation of MAPK1 1 0.00 0.59 0.21
54 INT277072 Binding of PLA2G7 and Lipg 1 0.00 1.32 0.21
55 INT118548 Msr1 Negative_regulation of CNR2 1 0.00 0 0.2
56 INT143618 Msr1 Positive_regulation of Adrb3 1 0.16 0.85 0.2
57 INT118547 Msr1 Negative_regulation of CNR1 1 0.00 0 0.2
58 INT134494 Binding of APOE and Alb 1 0.11 0.45 0.2
59 INT208360 Binding of Abca1 and Apoe 1 0.15 0.74 0.17
60 INT197499 Binding of Apoe and Tfrc 1 0.14 1.54 0.17
61 INT122528 Apoe Regulation of Eno2 1 0.05 0.29 0.16
62 INT122529 Apoe Regulation of S100B 1 0.18 0.29 0.16
63 INT297345 Apoe Negative_regulation of Csf2 1 0.17 0.66 0.16
64 INT329850 APOA5 Negative_regulation of Transcription of APOC3 1 0.24 0.85 0.15
65 INT87110 Apom Negative_regulation of Pde1a 1 0.00 0 0.15
66 INT297333 Apoe Negative_regulation of Positive_regulation of Tlr4 1 0.10 1.02 0.14
67 INT297343 Binding of Apoe and Tlr4 1 0.09 0.94 0.14
68 INT330486 MSR1 Negative_regulation of TAC1 1 0.01 0.23 0.13
69 INT297339 Tlr4 Negative_regulation of Gene_expression of Apoe 1 0.10 0.73 0.13
70 INT229290 BAS Negative_regulation of LDLR 1 0.03 0.83 0.13
71 INT330485 MSR1 Negative_regulation of TACR1 1 0.01 0.23 0.13
72 INT270723 Negative_regulation of HMGCR Positive_regulation of LDLR 1 0.02 0.52 0.12
73 INT328313 Binding of CD36 and LDLR 1 0.00 0.63 0.11
74 INT99140 LDLR Positive_regulation of Localization of VCAM1 1 0.05 0.44 0.11
75 INT208361 Positive_regulation of Binding of Apoe and Hdl1 1 0.12 1.22 0.1
76 INT350820 INS Regulation of SELS 1 0.13 1.11 0.1
77 INT297346 Apoe Negative_regulation of Localization of TNF 1 0.48 0.26 0.1
78 INT308585 Binding of APOB and PLA2G7 1 0.07 0.69 0.09
79 INT205135 Binding of APOE and APP 1 0.05 0.35 0.08
80 INT300641 Binding of APOE and CRP 1 0.41 0.81 0.07
81 INT297330 Apoe Positive_regulation of Gene_expression of Nos2 1 0.26 0.34 0.07
82 INT308665 Binding of Apoe and Gopc 1 0.02 0.49 0.07
83 INT308663 Apoe Regulation of Car2 1 0.02 0.44 0.07
84 INT50078 Binding of APOE and NPPA 1 0.30 0.42 0.07
85 INT326067 APOA1 Positive_regulation of Localization of APOE 1 0.61 4.22 0.07
86 INT71344 Ldlr Positive_regulation of Hdlcl1 1 0.01 0.69 0.06
87 INT66590 Gnrhr Regulation of Ldlr 1 0.02 0.4 0.06
88 INT71343 Negative_regulation of Ldlr Positive_regulation of Hdlcl1 1 0.01 0.69 0.06
89 INT350823 Binding of SAA1 and SELS 1 0.17 2.75 0.05
90 INT251468 Binding of APOE and DBT 1 0.03 1.18 0.05
91 INT323056 LDLR Regulation of HSD11B1 1 0.01 1.2 0.05
92 INT231395 Binding of HSD11B1 and Apob 1 0.27 1.18 0.04
93 INT288853 Binding of HSD11B1 and LDLR 1 0.26 1.52 0.04
94 INT208356 Hdl1 Positive_regulation of Apoe 1 0.12 1.25 0.04
95 INT206083 LDLR Positive_regulation of Binding of STAT3 1 0.02 0.53 0.04
96 INT186187 LDLR Regulation of Gene_expression of SCARB1 1 0.17 1.71 0.04
97 INT293899 UPF1 Positive_regulation of Gene_expression of APOB 1 0.01 0 0.04
98 INT235551 Gene_expression of Hras1 Negative_regulation of Positive_regulation of Apoe 1 0.03 0.57 0.04
99 INT240623 Binding of CRP and Apob 1 0.01 0.52 0.04
100 INT290180 Binding of APOB and PLTP 1 0.19 0.6 0.04
101 INT208357 Hdl1 Positive_regulation of Localization of Apoe 1 0.12 1.26 0.04
102 INT294217 Binding of PLG and Ldlr 1 0.33 0.06 0.04
103 INT206066 LDLR Positive_regulation of Phosphorylation of STAT3 1 0.02 0.52 0.04
104 INT208350 Positive_regulation of Hdl1 Positive_regulation of Apoe 1 0.12 1.27 0.04
105 INT290181 Binding of APOE and PLTP 1 0.17 1.61 0.04
106 INT294210 Binding of Ldlr and Plat 1 0.42 0.06 0.04
107 INT294206 Ldlr Positive_regulation of Grin1 1 0.26 0 0.03
108 INT257513 Regulation of Binding of Slc4a4 and H47 1 0.00 0.08 0.03
109 INT194483 Binding of Apoe and Chol1 1 0.24 0.51 0.03
110 INT257512 Binding of Slc4a4 and H47 1 0.00 0.08 0.03
111 INT208352 Apoe Regulation of Localization of Em 1 0.04 1.15 0.03
112 INT186186 LDLR Regulation of SCARB1 1 0.08 0.65 0.03
113 INT194481 Binding of Apoe and Apob 1 0.07 0.51 0.03
114 INT308658 Binding of Apoa2 and Apoe 1 0.17 0.15 0.03
115 INT194486 Binding of SNRNP70 and Apob 1 0.00 0.64 0.03
116 INT239351 Binding of CETP and Ldlr 1 0.15 1.01 0.03
117 INT251961 Binding of LDLR and SNRNP70 2 0.04 0.55 0
118 INT230134 Binding of SORL1 and BACE1 1 0.19 0.09 0
119 INT209984 Binding of LDLR and LRP1 1 0.08 0 0
120 INT247435 Binding of APOB and SNRNP70 1 0.04 2.2 0
121 INT198920 Binding of Ldlr and Lrpap1 1 0.05 0.06 0
122 INT353795 Binding of Cd320 and Apob 1 0.08 0.82 0
123 INT356117 Binding of SORL1 and Apbb1 1 0.14 0.43 0
124 INT171598 Binding of APOB and Lipg 1 0.01 0.63 0
125 INT308584 Binding of PLA2G7 and ANGPTL5 1 0.02 0.61 0
126 INT341487 Binding of APOE and TLR2 1 0.00 0.3 0
127 INT326065 APOE Positive_regulation of LCAT 1 0.53 0.84 0
128 INT308583 Binding of CRP and PLA2G7 1 0.28 1.23 0
129 INT353798 Binding of Hdl1 and Apob 1 0.01 0.82 0
130 INT209987 Binding of APOE and LDLR 1 0.24 0 0
131 INT208349 Regulation of Binding of Apoc3 and Apoe 1 0.01 0.38 0
132 INT350822 SELS Positive_regulation of Gene_expression of SAA1 1 0.21 0.87 0
133 INT130416 TNFSF14 Positive_regulation of Positive_regulation of MSR1 1 0.38 0 0
134 INT90283 Binding of APOE and Il1a 1 0.01 0 0
135 INT206086 LDLR Positive_regulation of Localization of IL6 1 0.03 0.42 0
136 INT298849 Binding of APOB and MCC 1 0.00 0.38 0
137 INT316414 Binding of LDLR and T2dm2 1 0.00 1.54 0
138 INT201080 Binding of APOE and HLA-C 1 0.41 0.31 0
139 INT283865 Binding of MAPK1 and APOA5 1 0.00 0.22 0
140 INT353802 Binding of APOE and Apob 1 0.05 0.83 0
141 INT210417 APOB Negative_regulation of CYP2D6 1 0.01 0 0
142 INT283866 Binding of SVIL and APOA5 1 0.00 0.22 0
143 INT208355 Binding of Apoc3 and Apoe 1 0.01 0.76 0
144 INT298856 Binding of APOB and MTG1 1 0.00 0.38 0
145 INT230147 Binding of OSBP and SORL1 1 0.20 0.08 0
146 INT198933 Binding of Apoe and App 1 0.33 0.19 0
147 INT186189 LDLR Positive_regulation of Gene_expression of SCARB1 1 0.14 1.27 0
148 INT317842 Hdlcl1 Positive_regulation of Ldlr 1 0.00 1.11 0
149 INT250554 Binding of F5 and SELS 1 0.24 1.07 0
150 INT286444 PCSK9 Positive_regulation of Apob 1 0.02 0.49 0
151 INT302596 Eef1a2 Negative_regulation of LDLR 1 0.14 0.31 0
152 INT277047 Binding of APOB and LDLR 1 0.25 0.82 0
153 INT230141 OSBP Regulation of Gene_expression of SORL1 1 0.24 0.1 0
154 INT353801 Binding of APOE and Cd320 1 0.22 0.83 0
155 INT268459 Binding of LDLR and Olr1 1 0.00 0.78 0
156 INT239184 Msr1 Negative_regulation of Msra 1 0.21 0.13 0
157 INT356118 Binding of SORL1 and App 1 0.41 0.43 0
158 INT230146 Binding of APP and SORL1 1 0.20 0.17 0
159 INT344723 Niacr1 Positive_regulation of Binding of APOB 1 0.31 1.05 0
160 INT353796 Binding of Ldlr and Apob 1 0.06 0.82 0
161 INT250152 Binding of APOE and UBE4B 1 0.21 1.2 0
162 INT247438 Binding of APOB and SACM1L 1 0.28 2 0
163 INT267974 APOB Negative_regulation of HSD11B1 1 0.01 0.75 0
164 INT326059 APOA1 Positive_regulation of Gene_expression of APOE 1 0.61 0.38 0
165 INT130415 TNFSF14 Positive_regulation of MSR1 1 0.46 0 0
166 INT300199 PCSK9 Regulation of Gene_expression of LDLR 1 0.13 0.88 0
167 INT339699 LDLR Positive_regulation of SREBF2 1 0.08 1.08 0
168 INT350824 INS Positive_regulation of Gene_expression of SELS 1 0.22 0.85 0
169 INT235960 Binding of Aqp4 and H47 1 0.01 0.13 0
170 INT198925 Binding of App and Ldlr 1 0.14 0.15 0
171 INT339694 LDLR Positive_regulation of Gene_expression of SREBF2 1 0.08 1.08 0
172 INT283061 Binding of ERCC8 and LDLR 1 0.00 0.44 0
173 INT353804 Binding of APOE and Ldlr 1 0.16 0.84 0
174 INT326057 APOA1 Regulation of Localization of APOE 1 0.54 1.36 0
175 INT251964 Binding of LDLR and RS1 1 0.00 0.31 0
176 INT263868 Binding of Krt31 and H47 1 0.01 0.51 0
177 INT201082 Binding of APOE and HLA-B 1 0.54 1.54 0
178 INT247440 Binding of APOA1 and APOB 1 0.28 1.02 0
179 INT352794 Binding of APOB and FGF21 1 0.01 1.98 0
180 INT284093 VWF Negative_regulation of APOE 1 0.40 2.32 0
181 INT353797 Binding of Ldlr and Trf 1 0.04 0.19 0
182 INT353800 Binding of Ldlr and Cd320 1 0.29 0.83 0
183 INT298861 Binding of APOB and RAB7A 1 0.00 0.32 0
184 INT85010 Apo Regulation of Apob 1 0.00 0.14 0
185 INT312630 Agrn Positive_regulation of Ldlr 1 0.14 0.66 0
186 INT312769 Binding of Apoe and Pon1 1 0.04 0.86 0
187 INT353803 Binding of APOE and Hdl1 1 0.01 0.83 0
188 INT283899 Binding of Ephb2 and APOA5 1 0.00 0.67 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for low-density lipoprotein particle. They are ordered first by their pain relevance and then by number of times they were reported in low-density lipoprotein particle. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT116861 Gene_expression of Apoe 182 0.78 100.41 27.26
2 INT1087 Negative_regulation of Msr1 32 0.57 8.35 10.72
3 INT5164 Negative_regulation of Ldlr 83 0.58 55.01 7.87
4 INT197493 Localization of Apoe 61 0.79 27.48 7.06
5 INT10863 Positive_regulation of Ldlr 45 0.68 31.06 7.05
6 INT142264 Positive_regulation of Apoe 47 0.50 26.35 6.94
7 INT182351 Positive_regulation of Gene_expression of Apoe 38 0.50 19.78 6.72
8 INT11826 Positive_regulation of LDLR 62 0.62 45.09 6.21
9 INT63042 Binding of Apoe 59 0.48 31.23 5.88
10 INT4282 Regulation of Msr1 11 0.45 2.51 5.75
11 INT55758 Positive_regulation of Apoe 15 0.70 11.71 4.69
12 INT46350 Gene_expression of Msr1 32 0.65 29.39 4.55
13 INT28673 Gene_expression of APOB 51 0.73 34.02 3.95
14 INT15033 Gene_expression of Apoe 18 0.78 14.97 3.75
15 INT104624 Negative_regulation of Apoe 26 0.59 19.25 3.71
16 INT52047 Gene_expression of APOE 50 0.78 34.75 3.52
17 INT10106 Positive_regulation of Msr1 16 0.50 5.86 3.52
18 INT57728 Regulation of LDLR 25 0.41 13.18 3.46
19 INT87517 Gene_expression of LDLR 73 0.69 37.35 3.32
20 INT5166 Binding of Ldlr 14 0.48 11.95 3.32
21 INT72141 Binding of Apoe 11 0.37 10.91 3.27
22 INT250581 Gene_expression of SELS 4 0.78 47.37 3.27
23 INT97710 Localization of Apoe 1 0.79 7.18 3.2
24 INT207444 Gene_expression of PLA2G7 8 0.71 11.31 3.18
25 INT10057 Gene_expression of Ldlr 35 0.67 23.99 3.05
26 INT550 Negative_regulation of LDLR 66 0.43 44.71 3.04
27 INT194465 Gene_expression of Ldlr 27 0.76 31.36 2.73
28 INT50080 Binding of APOE 38 0.45 29.61 2.67
29 INT49473 Gene_expression of MSR1 14 0.75 7.28 2.64
30 INT97713 Negative_regulation of Apoe 4 0.59 4.57 2.52
31 INT65732 Binding of Msr1 9 0.47 7.28 2.42
32 INT208344 Positive_regulation of Localization of Apoe 22 0.48 9.6 2.27
33 INT142265 Regulation of Apoe 20 0.60 9.52 2.23
34 INT84060 Regulation of Apoe 4 0.62 3.33 2.05
35 INT40877 Positive_regulation of APOB 35 0.68 32.47 1.86
36 INT96814 Negative_regulation of APOE 13 0.59 10.64 1.61
37 INT1088 Negative_regulation of Negative_regulation of Msr1 5 0.40 0.65 1.61
38 INT9466 Binding of APOB 27 0.41 19.36 1.56
39 INT217388 Negative_regulation of Gene_expression of Apoe 11 0.59 6.07 1.4
40 INT113960 Positive_regulation of Gene_expression of APOB 8 0.49 5.88 1.39
41 INT37799 Gene_expression of Apob 13 0.56 10.59 1.36
42 INT97716 Transcription of Apoe 3 0.53 2.61 1.36
43 INT10829 Regulation of Ldlr 12 0.34 8.12 1.35
44 INT207451 Binding of PLA2G7 3 0.48 11.12 1.32
45 INT20238 Regulation of APOB 9 0.61 11.52 1.26
46 INT97715 Regulation of Gene_expression of Apoe 3 0.62 1.98 1.23
47 INT113336 Positive_regulation of Gene_expression of Apoe 3 0.70 1.79 1.23
48 INT23199 Binding of LDLR 22 0.47 17.08 1.16
49 INT82703 Transcription of LDLR 6 0.64 0.4 1.13
50 INT207454 Regulation of PLA2G7 5 0.49 3.55 1.12
51 INT207448 Negative_regulation of PLA2G7 5 0.47 5.65 1.08
52 INT217390 Negative_regulation of Positive_regulation of Apoe 3 0.37 1.95 1.05
53 INT207445 Positive_regulation of PLA2G7 7 0.63 7.66 1
54 INT82707 Positive_regulation of Transcription of LDLR 1 0.62 0.34 0.98
55 INT129425 Negative_regulation of Ldlr 22 0.42 17.15 0.97
56 INT97714 Negative_regulation of Localization of Apoe 1 0.58 1.83 0.97
57 INT82702 Positive_regulation of Positive_regulation of LDLR 4 0.45 1.08 0.95
58 INT10827 Gene_expression of Apob 16 0.78 13.08 0.9
59 INT9467 Negative_regulation of APOB 14 0.57 10.49 0.88
60 INT11949 Negative_regulation of Apob 11 0.09 8.13 0.85
61 INT207450 Regulation of Gene_expression of PLA2G7 1 0.49 2.18 0.85
62 INT10828 Regulation of Apob 7 0.39 7.55 0.83
63 INT142597 Regulation of Binding of Apoe 1 0.34 2.21 0.8
64 INT51739 Negative_regulation of Apob 9 0.42 4.21 0.78
65 INT10105 Regulation of Positive_regulation of Msr1 1 0.45 0 0.75
66 INT197495 Negative_regulation of Localization of Apoe 6 0.43 2.19 0.73
67 INT44612 Positive_regulation of APOE 16 0.67 5.73 0.72
68 INT270428 Negative_regulation of Binding of APOE 2 0.41 1.16 0.7
69 INT113335 Regulation of Transcription of Apoe 1 0.27 0.51 0.7
70 INT175580 Localization of APOE 10 0.76 18.84 0.65
71 INT142802 Binding of Ldlr 8 0.47 5.08 0.65
72 INT4281 Regulation of Negative_regulation of Msr1 2 0.23 0 0.65
73 INT97708 Regulation of Localization of Apoe 1 0.61 2.06 0.62
74 INT142800 Positive_regulation of Ldlr 21 0.68 14.75 0.6
75 INT200090 Positive_regulation of Gene_expression of Ldlr 5 0.37 3.67 0.59
76 INT113334 Positive_regulation of Positive_regulation of Apoe 1 0.50 0.6 0.56
77 INT49472 Binding of MSR1 3 0.36 0.07 0.53
78 INT239247 Positive_regulation of APOA5 7 0.37 3.68 0.51
79 INT197322 Protein_catabolism of Apoe 6 0.71 3.52 0.51
80 INT87741 Localization of Msr1 5 0.60 4.77 0.5
81 INT217370 Phosphorylation of Apoe 2 0.63 1.8 0.49
82 INT15047 Negative_regulation of SELS 1 0.35 0.34 0.49
83 INT37800 Positive_regulation of Apob 7 0.18 11.01 0.48
84 INT96816 Regulation of APOE 8 0.45 6.62 0.44
85 INT109492 Negative_regulation of Gene_expression of Msr1 2 0.06 0.58 0.42
86 INT100254 Binding of SELS 6 0.36 4.54 0.4
87 INT197012 Regulation of Gene_expression of LDLR 4 0.40 1.31 0.4
88 INT97712 Negative_regulation of Transcription of Apoe 1 0.43 1.05 0.4
89 INT161811 Positive_regulation of Gene_expression of Msr1 5 0.49 6.38 0.38
90 INT138380 Regulation of Transcription of Ldlr 1 0.38 0.21 0.38
91 INT138379 Transcription of Ldlr 1 0.59 0.21 0.38
92 INT252223 Positive_regulation of Gene_expression of Ldlr 3 0.55 10.28 0.37
93 INT5168 Regulation of Binding of Ldlr 1 0.45 0 0.36
94 INT21562 Negative_regulation of Regulation of Msr1 1 0.07 0.09 0.35
95 INT339386 Negative_regulation of Gene_expression of Apob 3 0.43 1.91 0.34
96 INT232235 Negative_regulation of Gene_expression of Ldlr 3 0.42 3.13 0.34
97 INT131542 Negative_regulation of Gene_expression of APOE 6 0.40 3.92 0.33
98 INT26173 Regulation of SELS 3 0.52 3.4 0.32
99 INT350833 Positive_regulation of Gene_expression of SELS 1 0.61 6.07 0.32
100 INT207447 Negative_regulation of Gene_expression of PLA2G7 3 0.43 1.76 0.31
101 INT83352 Positive_regulation of Negative_regulation of APOB 1 0.01 0.69 0.31
102 INT311128 Positive_regulation of Regulation of Apoe 1 0.30 0.3 0.3
103 INT175687 Transcription of Apoe 4 0.72 2.12 0.29
104 INT96815 Regulation of Gene_expression of APOE 2 0.62 1.1 0.29
105 INT97711 Positive_regulation of Transcription of Apoe 1 0.46 1.06 0.27
106 INT254756 Regulation of Positive_regulation of Apoe 1 0.20 0.22 0.26
107 INT207452 Localization of PLA2G7 1 0.68 0.74 0.25
108 INT350825 Gene_expression of Sels 1 0.34 1.07 0.25
109 INT197016 Positive_regulation of Gene_expression of LDLR 13 0.50 5.82 0.24
110 INT37790 Localization of Ldlr 5 0.38 2.29 0.23
111 INT247452 Gene_expression of APOA5 4 0.54 5.71 0.22
112 INT194472 Positive_regulation of Gene_expression of Apob 2 0.15 1.71 0.22
113 INT283891 Positive_regulation of Gene_expression of APOA5 1 0.01 1.36 0.22
114 INT323964 Negative_regulation of Binding of Apoe 1 0.39 0.35 0.22
115 INT87742 Regulation of Localization of Msr1 1 0.03 0.44 0.22
116 INT198892 Regulation of Binding of Apoe 6 0.45 2.94 0.21
117 INT305975 Regulation of Gene_expression of SELS 2 0.60 3.19 0.21
118 INT283877 Localization of APOA5 3 0.27 1.48 0.2
119 INT193810 Phosphorylation of APOE 2 0.27 1.13 0.2
120 INT252222 Regulation of Ldlr 5 0.34 4.3 0.19
121 INT203836 Negative_regulation of Negative_regulation of Apob 1 0.18 0.45 0.19
122 INT5165 Positive_regulation of Binding of Ldlr 1 0.50 0 0.19
123 INT350827 Localization of SELS 1 0.62 1.24 0.19
124 INT305978 Protein_catabolism of SELS 1 0.86 0.88 0.17
125 INT5167 Negative_regulation of Binding of Ldlr 1 0.43 0 0.17
126 INT254754 Regulation of Localization of Apoe 1 0.20 0.39 0.17
127 INT17474 Negative_regulation of Positive_regulation of LDLR 4 0.37 2.93 0.16
128 INT62274 Negative_regulation of Gene_expression of APOB 4 0.32 5.9 0.16
129 INT209992 Negative_regulation of Transcription of LDLR 2 0.29 0 0.16
130 INT87515 Negative_regulation of Gene_expression of LDLR 2 0.09 1.96 0.16
131 INT277049 Regulation of Binding of APOB 1 0.27 0.91 0.16
132 INT254755 Positive_regulation of Transcription of Apoe 1 0.16 0.41 0.16
133 INT96772 Positive_regulation of Gene_expression of APOE 5 0.66 5.44 0.14
134 INT198894 Regulation of Gene_expression of Apoe 2 0.44 0.56 0.14
135 INT211532 Localization of Ldlr 4 0.56 3.52 0.13
136 INT191137 Binding of H47 4 0.19 1.22 0.13
137 INT203827 Localization of Apob 3 0.32 1.81 0.13
138 INT240040 Protein_catabolism of Apob 1 0.01 1.79 0.13
139 INT350834 Transcription of SELS 1 0.53 4.8 0.13
140 INT240041 Negative_regulation of Protein_catabolism of Apob 1 0.01 1.8 0.13
141 INT350832 Positive_regulation of Transcription of SELS 1 0.41 1 0.13
142 INT194469 Positive_regulation of Apob 3 0.15 2.29 0.12
143 INT104623 Regulation of Negative_regulation of Apoe 2 0.45 0.73 0.12
144 INT215136 Regulation of Gene_expression of Ldlr 2 0.12 0.76 0.12
145 INT169910 Positive_regulation of H47 1 0.17 1.52 0.12
146 INT116739 Protein_catabolism of Ldlr 1 0.87 1.18 0.12
147 INT326081 Negative_regulation of Localization of APOE 1 0.56 2.23 0.11
148 INT34582 Negative_regulation of Positive_regulation of Ldlr 2 0.03 1.33 0.1
149 INT250570 Negative_regulation of Gene_expression of SELS 2 0.43 2.85 0.1
150 INT235511 Transcription of Apob 1 0.13 0.45 0.1
151 INT308586 Negative_regulation of Binding of PLA2G7 1 0.43 0.69 0.1
152 INT169948 Gene_expression of H47 6 0.22 0.73 0.09
153 INT300643 Positive_regulation of Binding of APOE 1 0.44 0.8 0.09
154 INT44609 Negative_regulation of Positive_regulation of APOE 1 0.16 0.9 0.09
155 INT167019 Negative_regulation of Gene_expression of Ldlr 3 0.42 0.76 0.08
156 INT293307 Regulation of Gene_expression of Ldlr 3 0.19 2.77 0.07
157 INT213136 Binding of Apob 2 0.03 2.76 0.07
158 INT213138 Negative_regulation of Binding of Apob 1 0.03 0.86 0.07
159 INT205147 Regulation of Phosphorylation of APOE 1 0.06 0.34 0.07
160 INT97709 Positive_regulation of Localization of Apoe 1 0.68 1.02 0.07
161 INT213137 Positive_regulation of Binding of Apob 1 0.04 0.87 0.07
162 INT179763 Localization of Apob 6 0.66 4.72 0.06
163 INT239409 Transcription of APOB 3 0.65 1.86 0.06
164 INT235517 Positive_regulation of Positive_regulation of Apob 1 0.10 0.58 0.06
165 INT183389 Regulation of Apob 4 0.01 5.17 0.05
166 INT255451 Positive_regulation of Positive_regulation of APOB 2 0.37 1.91 0.05
167 INT208336 Positive_regulation of Binding of Apoe 1 0.48 0.7 0.05
168 INT208333 Positive_regulation of Positive_regulation of Apoe 1 0.48 0.65 0.05
169 INT191149 Positive_regulation of Binding of H47 1 0.07 0.55 0.05
170 INT191140 Negative_regulation of Binding of H47 1 0.06 0.56 0.05
171 INT348079 Negative_regulation of Negative_regulation of Ldlr 1 0.12 1.03 0.05
172 INT239411 Localization of APOB 10 0.76 5.71 0.04
173 INT240615 Binding of Apob 2 0.07 0.85 0.04
174 INT246579 Negative_regulation of Localization of APOB 1 0.05 0.23 0.04
175 INT197014 Localization of LDLR 8 0.63 3.29 0.03
176 INT130421 Positive_regulation of MSR1 3 0.67 0.57 0.03
177 INT297432 Positive_regulation of Localization of Ldlr 2 0.14 0.35 0.03
178 INT325018 Regulation of Gene_expression of Apob 2 0.16 1.59 0.03
179 INT196698 Regulation of Gene_expression of Msr1 1 0.44 0.86 0.03
180 INT169923 Negative_regulation of Positive_regulation of H47 1 0.12 0.72 0.03
181 INT252743 Protein_catabolism of APOB 1 0.01 1.68 0.03
182 INT252758 Positive_regulation of Protein_catabolism of APOB 1 0.01 0.98 0.03
183 INT326070 Regulation of Localization of APOE 1 0.58 1.21 0.03
184 INT37798 Positive_regulation of Positive_regulation of Apob 1 0.06 1 0.03
185 INT191285 Positive_regulation of Localization of APOE 3 0.66 3.06 0
186 INT230175 Negative_regulation of Gene_expression of SORL1 2 0.42 0.38 0
187 INT176889 Negative_regulation of Binding of LDLR 2 0.41 1.2 0
188 INT326073 Transcription of APOE 2 0.51 1.94 0
189 INT50081 Positive_regulation of Positive_regulation of APOE 2 0.49 0.18 0
190 INT276260 Negative_regulation of Localization of LDLR 2 0.40 1.34 0
191 INT230160 Positive_regulation of Gene_expression of SORL1 2 0.67 0.8 0
192 INT247458 Binding of APOA5 2 0.38 0.52 0
193 INT230163 Gene_expression of SORL1 2 0.75 1.36 0
194 INT179761 Negative_regulation of Localization of Apob 2 0.40 2.9 0
195 INT225419 Positive_regulation of Gene_expression of H47 1 0.08 0 0
196 INT325305 Localization of MSR1 1 0.10 1.43 0
197 INT255450 Positive_regulation of Binding of APOB 1 0.37 2.88 0
198 INT229627 Negative_regulation of Negative_regulation of APOB 1 0.31 0.26 0
199 INT241542 Regulation of Gene_expression of Apob 1 0.00 1.8 0
200 INT39405 Regulation of Binding of LDLR 1 0.17 0 0
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