GO:0034363

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Name intermediate-density lipoprotein particle
Categary Component
Go Slim No
Go Link GO:0034363
Unique Molecular Interactions 122
Total Molecular Interactions 174
Total Single Events 1310
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for intermediate-density lipoprotein particle. They are ordered first by their pain relevance and then by number of times they were reported for intermediate-density lipoprotein particle. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT297332 Apoe Negative_regulation of Gene_expression of Mpz 1 0.02 1.09 0.87
2 INT208354 Binding of Apoe and Hdl1 12 0.13 8.37 0.77
3 INT297344 Apoe Regulation of Binding of Alms1 1 0.08 1.1 0.61
4 INT297340 Apoe Regulation of Binding of Smo 1 0.10 1.1 0.6
5 INT297331 Apoe Negative_regulation of Gene_expression of Il6 1 0.14 0.61 0.57
6 INT254761 Igh-Dex Positive_regulation of Apoe 1 0.00 0.08 0.52
7 INT116862 Apoe Positive_regulation of Il10 1 0.30 0.69 0.5
8 INT116863 Apoe Negative_regulation of Hand1 1 0.37 0.69 0.5
9 INT254768 DNMT1 Positive_regulation of Gene_expression of Apoe 1 0.02 0.05 0.49
10 INT197496 Binding of Apoe and Lrp1 4 0.22 2.32 0.46
11 INT142608 Apoe Regulation of Gene_expression of Il6 1 0.25 1.01 0.44
12 INT254760 Igh-Dex Positive_regulation of Gene_expression of Apoe 1 0.00 0 0.42
13 INT329085 Csf2 Positive_regulation of Apoe 1 0.00 1.23 0.42
14 INT240617 Binding of APOB and ADIPOQ 1 0.04 3.62 0.38
15 INT297335 Binding of Apoc3 and Hdl1 1 0.00 0.92 0.29
16 INT254759 Igh-Dex Positive_regulation of Localization of Apoe 1 0.00 0.32 0.28
17 INT254769 Binding of LDLR and Apoe 1 0.03 0 0.28
18 INT297338 Apoe Regulation of Gnb5 1 0.06 1.12 0.27
19 INT141635 Binding of APOB and Alb 1 0.02 0.3 0.26
20 INT254772 DNMT1 Positive_regulation of Apoe 1 0.02 0 0.25
21 INT78293 Binding of Apoe and Ldlr 1 0.20 0.25 0.24
22 INT78295 Binding of Ptpra and Apoe 1 0.42 0.25 0.24
23 INT297334 Gnb5 Regulation of Apoe 1 0.09 0.83 0.24
24 INT78294 Negative_regulation of Binding of Ptpra and Apoe 1 0.48 0.25 0.24
25 INT254773 PPARA Positive_regulation of Gene_expression of Apoe 1 0.01 0.07 0.24
26 INT78292 Negative_regulation of Binding of Apoe and Ldlr 1 0.23 0.25 0.24
27 INT254774 DNMT1 Positive_regulation of Localization of Apoe 1 0.01 0.31 0.23
28 INT134494 Binding of APOE and Alb 1 0.11 0.45 0.2
29 INT208360 Binding of Abca1 and Apoe 1 0.15 0.74 0.17
30 INT197499 Binding of Apoe and Tfrc 1 0.14 1.54 0.17
31 INT122528 Apoe Regulation of Eno2 1 0.05 0.29 0.16
32 INT122529 Apoe Regulation of S100B 1 0.18 0.29 0.16
33 INT297345 Apoe Negative_regulation of Csf2 1 0.17 0.66 0.16
34 INT329850 APOA5 Negative_regulation of Transcription of APOC3 1 0.24 0.85 0.15
35 INT297333 Apoe Negative_regulation of Positive_regulation of Tlr4 1 0.10 1.02 0.14
36 INT297343 Binding of Apoe and Tlr4 1 0.09 0.94 0.14
37 INT297339 Tlr4 Negative_regulation of Gene_expression of Apoe 1 0.10 0.73 0.13
38 INT208361 Positive_regulation of Binding of Apoe and Hdl1 1 0.12 1.22 0.1
39 INT297346 Apoe Negative_regulation of Localization of TNF 1 0.48 0.26 0.1
40 INT308585 Binding of APOB and PLA2G7 1 0.07 0.69 0.09
41 INT205135 Binding of APOE and APP 1 0.05 0.35 0.08
42 INT300641 Binding of APOE and CRP 1 0.41 0.81 0.07
43 INT297330 Apoe Positive_regulation of Gene_expression of Nos2 1 0.26 0.34 0.07
44 INT308665 Binding of Apoe and Gopc 1 0.02 0.49 0.07
45 INT308663 Apoe Regulation of Car2 1 0.02 0.44 0.07
46 INT50078 Binding of APOE and NPPA 1 0.30 0.42 0.07
47 INT326067 APOA1 Positive_regulation of Localization of APOE 1 0.61 4.22 0.07
48 INT251468 Binding of APOE and DBT 1 0.03 1.18 0.05
49 INT208353 Binding of Apoc4 and Apoc3 1 0.00 2.56 0.04
50 INT231395 Binding of HSD11B1 and Apob 1 0.27 1.18 0.04
51 INT325027 Apoc3 Negative_regulation of Pnlip 1 0.01 1.02 0.04
52 INT208356 Hdl1 Positive_regulation of Apoe 1 0.12 1.25 0.04
53 INT293899 UPF1 Positive_regulation of Gene_expression of APOB 1 0.01 0 0.04
54 INT235551 Gene_expression of Hras1 Negative_regulation of Positive_regulation of Apoe 1 0.03 0.57 0.04
55 INT240623 Binding of CRP and Apob 1 0.01 0.52 0.04
56 INT290180 Binding of APOB and PLTP 1 0.19 0.6 0.04
57 INT208357 Hdl1 Positive_regulation of Localization of Apoe 1 0.12 1.26 0.04
58 INT325026 Apoc3 Negative_regulation of Lpl 1 0.03 1.01 0.04
59 INT208350 Positive_regulation of Hdl1 Positive_regulation of Apoe 1 0.12 1.27 0.04
60 INT290181 Binding of APOE and PLTP 1 0.17 1.61 0.04
61 INT194483 Binding of Apoe and Chol1 1 0.24 0.51 0.03
62 INT208352 Apoe Regulation of Localization of Em 1 0.04 1.15 0.03
63 INT194481 Binding of Apoe and Apob 1 0.07 0.51 0.03
64 INT308658 Binding of Apoa2 and Apoe 1 0.17 0.15 0.03
65 INT194486 Binding of SNRNP70 and Apob 1 0.00 0.64 0.03
66 INT332978 ACOX1 Negative_regulation of Transcription of Apoc3 1 0.00 0.98 0
67 INT247435 Binding of APOB and SNRNP70 1 0.04 2.2 0
68 INT353795 Binding of Cd320 and Apob 1 0.08 0.82 0
69 INT171598 Binding of APOB and Lipg 1 0.01 0.63 0
70 INT341487 Binding of APOE and TLR2 1 0.00 0.3 0
71 INT247441 Binding of APOC3 and SNRNP70 1 0.04 0.26 0
72 INT326065 APOE Positive_regulation of LCAT 1 0.53 0.84 0
73 INT353798 Binding of Hdl1 and Apob 1 0.01 0.82 0
74 INT209987 Binding of APOE and LDLR 1 0.24 0 0
75 INT247444 Binding of APOA1 and APOC3 1 0.28 0.39 0
76 INT208349 Regulation of Binding of Apoc3 and Apoe 1 0.01 0.38 0
77 INT171599 Binding of APOC3 and Sst1 1 0.01 0.68 0
78 INT90283 Binding of APOE and Il1a 1 0.01 0 0
79 INT208365 Apoc3 Positive_regulation of Localization of PROC 1 0.00 1.13 0
80 INT298849 Binding of APOB and MCC 1 0.00 0.38 0
81 INT201080 Binding of APOE and HLA-C 1 0.41 0.31 0
82 INT332962 Acaa1a Negative_regulation of Transcription of Apoc3 1 0.01 0.93 0
83 INT353802 Binding of APOE and Apob 1 0.05 0.83 0
84 INT210417 APOB Negative_regulation of CYP2D6 1 0.01 0 0
85 INT208355 Binding of Apoc3 and Apoe 1 0.01 0.76 0
86 INT298856 Binding of APOB and MTG1 1 0.00 0.38 0
87 INT198933 Binding of Apoe and App 1 0.33 0.19 0
88 INT286444 PCSK9 Positive_regulation of Apob 1 0.02 0.49 0
89 INT277047 Binding of APOB and LDLR 1 0.25 0.82 0
90 INT353801 Binding of APOE and Cd320 1 0.22 0.83 0
91 INT344723 Niacr1 Positive_regulation of Binding of APOB 1 0.31 1.05 0
92 INT353796 Binding of Ldlr and Apob 1 0.06 0.82 0
93 INT250152 Binding of APOE and UBE4B 1 0.21 1.2 0
94 INT247438 Binding of APOB and SACM1L 1 0.28 2 0
95 INT267974 APOB Negative_regulation of HSD11B1 1 0.01 0.75 0
96 INT326059 APOA1 Positive_regulation of Gene_expression of APOE 1 0.61 0.38 0
97 INT171602 APOC3 Negative_regulation of Lipg 1 0.04 0.38 0
98 INT353804 Binding of APOE and Ldlr 1 0.16 0.84 0
99 INT326057 APOA1 Regulation of Localization of APOE 1 0.54 1.36 0
100 INT201082 Binding of APOE and HLA-B 1 0.54 1.54 0
101 INT247440 Binding of APOA1 and APOB 1 0.28 1.02 0
102 INT352794 Binding of APOB and FGF21 1 0.01 1.98 0
103 INT284093 VWF Negative_regulation of APOE 1 0.40 2.32 0
104 INT298861 Binding of APOB and RAB7A 1 0.00 0.32 0
105 INT85010 Apo Regulation of Apob 1 0.00 0.14 0
106 INT312769 Binding of Apoe and Pon1 1 0.04 0.86 0
107 INT353803 Binding of APOE and Hdl1 1 0.01 0.83 0
108 INT171603 APOC3 Negative_regulation of Lpl 1 0.48 0.38 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for intermediate-density lipoprotein particle. They are ordered first by their pain relevance and then by number of times they were reported in intermediate-density lipoprotein particle. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT116861 Gene_expression of Apoe 182 0.78 100.41 27.26
2 INT197493 Localization of Apoe 61 0.79 27.48 7.06
3 INT142264 Positive_regulation of Apoe 47 0.50 26.35 6.94
4 INT182351 Positive_regulation of Gene_expression of Apoe 38 0.50 19.78 6.72
5 INT63042 Binding of Apoe 59 0.48 31.23 5.88
6 INT55758 Positive_regulation of Apoe 15 0.70 11.71 4.69
7 INT28673 Gene_expression of APOB 51 0.73 34.02 3.95
8 INT15033 Gene_expression of Apoe 18 0.78 14.97 3.75
9 INT104624 Negative_regulation of Apoe 26 0.59 19.25 3.71
10 INT52047 Gene_expression of APOE 50 0.78 34.75 3.52
11 INT72141 Binding of Apoe 11 0.37 10.91 3.27
12 INT97710 Localization of Apoe 1 0.79 7.18 3.2
13 INT50080 Binding of APOE 38 0.45 29.61 2.67
14 INT97713 Negative_regulation of Apoe 4 0.59 4.57 2.52
15 INT208344 Positive_regulation of Localization of Apoe 22 0.48 9.6 2.27
16 INT142265 Regulation of Apoe 20 0.60 9.52 2.23
17 INT84060 Regulation of Apoe 4 0.62 3.33 2.05
18 INT190883 Gene_expression of Apoc3 16 0.38 14.18 1.93
19 INT40877 Positive_regulation of APOB 35 0.68 32.47 1.86
20 INT96814 Negative_regulation of APOE 13 0.59 10.64 1.61
21 INT9466 Binding of APOB 27 0.41 19.36 1.56
22 INT217388 Negative_regulation of Gene_expression of Apoe 11 0.59 6.07 1.4
23 INT113960 Positive_regulation of Gene_expression of APOB 8 0.49 5.88 1.39
24 INT37799 Gene_expression of Apob 13 0.56 10.59 1.36
25 INT97716 Transcription of Apoe 3 0.53 2.61 1.36
26 INT20238 Regulation of APOB 9 0.61 11.52 1.26
27 INT97715 Regulation of Gene_expression of Apoe 3 0.62 1.98 1.23
28 INT113336 Positive_regulation of Gene_expression of Apoe 3 0.70 1.79 1.23
29 INT217390 Negative_regulation of Positive_regulation of Apoe 3 0.37 1.95 1.05
30 INT97714 Negative_regulation of Localization of Apoe 1 0.58 1.83 0.97
31 INT10827 Gene_expression of Apob 16 0.78 13.08 0.9
32 INT9467 Negative_regulation of APOB 14 0.57 10.49 0.88
33 INT11949 Negative_regulation of Apob 11 0.09 8.13 0.85
34 INT10828 Regulation of Apob 7 0.39 7.55 0.83
35 INT142597 Regulation of Binding of Apoe 1 0.34 2.21 0.8
36 INT51739 Negative_regulation of Apob 9 0.42 4.21 0.78
37 INT197495 Negative_regulation of Localization of Apoe 6 0.43 2.19 0.73
38 INT44612 Positive_regulation of APOE 16 0.67 5.73 0.72
39 INT270428 Negative_regulation of Binding of APOE 2 0.41 1.16 0.7
40 INT113335 Regulation of Transcription of Apoe 1 0.27 0.51 0.7
41 INT175580 Localization of APOE 10 0.76 18.84 0.65
42 INT97708 Regulation of Localization of Apoe 1 0.61 2.06 0.62
43 INT113334 Positive_regulation of Positive_regulation of Apoe 1 0.50 0.6 0.56
44 INT197322 Protein_catabolism of Apoe 6 0.71 3.52 0.51
45 INT217370 Phosphorylation of Apoe 2 0.63 1.8 0.49
46 INT37800 Positive_regulation of Apob 7 0.18 11.01 0.48
47 INT96816 Regulation of APOE 8 0.45 6.62 0.44
48 INT335112 Regulation of Localization of APOC3 1 0.13 0.73 0.4
49 INT97712 Negative_regulation of Transcription of Apoe 1 0.43 1.05 0.4
50 INT335117 Localization of APOC3 1 0.40 0.73 0.4
51 INT339386 Negative_regulation of Gene_expression of Apob 3 0.43 1.91 0.34
52 INT131542 Negative_regulation of Gene_expression of APOE 6 0.40 3.92 0.33
53 INT83352 Positive_regulation of Negative_regulation of APOB 1 0.01 0.69 0.31
54 INT190878 Positive_regulation of Gene_expression of Apoc3 3 0.29 2.76 0.3
55 INT311128 Positive_regulation of Regulation of Apoe 1 0.30 0.3 0.3
56 INT175687 Transcription of Apoe 4 0.72 2.12 0.29
57 INT96815 Regulation of Gene_expression of APOE 2 0.62 1.1 0.29
58 INT97711 Positive_regulation of Transcription of Apoe 1 0.46 1.06 0.27
59 INT254756 Regulation of Positive_regulation of Apoe 1 0.20 0.22 0.26
60 INT194472 Positive_regulation of Gene_expression of Apob 2 0.15 1.71 0.22
61 INT323964 Negative_regulation of Binding of Apoe 1 0.39 0.35 0.22
62 INT198892 Regulation of Binding of Apoe 6 0.45 2.94 0.21
63 INT171597 Gene_expression of APOC3 9 0.77 3.18 0.2
64 INT193810 Phosphorylation of APOE 2 0.27 1.13 0.2
65 INT335113 Negative_regulation of Gene_expression of APOC3 1 0.24 0.34 0.2
66 INT203836 Negative_regulation of Negative_regulation of Apob 1 0.18 0.45 0.19
67 INT208335 Binding of Apoc3 3 0.01 2.11 0.18
68 INT190876 Negative_regulation of Apoc3 2 0.15 1.43 0.17
69 INT254754 Regulation of Localization of Apoe 1 0.20 0.39 0.17
70 INT62274 Negative_regulation of Gene_expression of APOB 4 0.32 5.9 0.16
71 INT277049 Regulation of Binding of APOB 1 0.27 0.91 0.16
72 INT254755 Positive_regulation of Transcription of Apoe 1 0.16 0.41 0.16
73 INT171595 Negative_regulation of APOC3 3 0.43 1.99 0.15
74 INT171589 Transcription of APOC3 2 0.71 1.25 0.15
75 INT96772 Positive_regulation of Gene_expression of APOE 5 0.66 5.44 0.14
76 INT198894 Regulation of Gene_expression of Apoe 2 0.44 0.56 0.14
77 INT203827 Localization of Apob 3 0.32 1.81 0.13
78 INT190877 Regulation of Gene_expression of Apoc3 2 0.11 2.09 0.13
79 INT240040 Protein_catabolism of Apob 1 0.01 1.79 0.13
80 INT240041 Negative_regulation of Protein_catabolism of Apob 1 0.01 1.8 0.13
81 INT194469 Positive_regulation of Apob 3 0.15 2.29 0.12
82 INT104623 Regulation of Negative_regulation of Apoe 2 0.45 0.73 0.12
83 INT326081 Negative_regulation of Localization of APOE 1 0.56 2.23 0.11
84 INT208332 Positive_regulation of Apoc3 4 0.29 3.3 0.1
85 INT235511 Transcription of Apob 1 0.13 0.45 0.1
86 INT300643 Positive_regulation of Binding of APOE 1 0.44 0.8 0.09
87 INT44609 Negative_regulation of Positive_regulation of APOE 1 0.16 0.9 0.09
88 INT213136 Binding of Apob 2 0.03 2.76 0.07
89 INT213138 Negative_regulation of Binding of Apob 1 0.03 0.86 0.07
90 INT205147 Regulation of Phosphorylation of APOE 1 0.06 0.34 0.07
91 INT97709 Positive_regulation of Localization of Apoe 1 0.68 1.02 0.07
92 INT213137 Positive_regulation of Binding of Apob 1 0.04 0.87 0.07
93 INT179763 Localization of Apob 6 0.66 4.72 0.06
94 INT239409 Transcription of APOB 3 0.65 1.86 0.06
95 INT235517 Positive_regulation of Positive_regulation of Apob 1 0.10 0.58 0.06
96 INT183389 Regulation of Apob 4 0.01 5.17 0.05
97 INT255451 Positive_regulation of Positive_regulation of APOB 2 0.37 1.91 0.05
98 INT208336 Positive_regulation of Binding of Apoe 1 0.48 0.7 0.05
99 INT208333 Positive_regulation of Positive_regulation of Apoe 1 0.48 0.65 0.05
100 INT239411 Localization of APOB 10 0.76 5.71 0.04
101 INT240615 Binding of Apob 2 0.07 0.85 0.04
102 INT246579 Negative_regulation of Localization of APOB 1 0.05 0.23 0.04
103 INT325018 Regulation of Gene_expression of Apob 2 0.16 1.59 0.03
104 INT252743 Protein_catabolism of APOB 1 0.01 1.68 0.03
105 INT252758 Positive_regulation of Protein_catabolism of APOB 1 0.01 0.98 0.03
106 INT326070 Regulation of Localization of APOE 1 0.58 1.21 0.03
107 INT37798 Positive_regulation of Positive_regulation of Apob 1 0.06 1 0.03
108 INT171594 Binding of APOC3 5 0.37 3.97 0
109 INT191285 Positive_regulation of Localization of APOE 3 0.66 3.06 0
110 INT326073 Transcription of APOE 2 0.51 1.94 0
111 INT50081 Positive_regulation of Positive_regulation of APOE 2 0.49 0.18 0
112 INT179761 Negative_regulation of Localization of Apob 2 0.40 2.9 0
113 INT255450 Positive_regulation of Binding of APOB 1 0.37 2.88 0
114 INT229627 Negative_regulation of Negative_regulation of APOB 1 0.31 0.26 0
115 INT171590 Regulation of Gene_expression of APOC3 1 0.61 0.41 0
116 INT241542 Regulation of Gene_expression of Apob 1 0.00 1.8 0
117 INT332950 Negative_regulation of Transcription of Apoc3 1 0.03 0.92 0
118 INT171592 Positive_regulation of APOC3 1 0.46 0.63 0
119 INT332957 Transcription of Apoc3 1 0.06 0.91 0
120 INT317658 Positive_regulation of Gene_expression of Apob 1 0.17 1.59 0
121 INT332948 Negative_regulation of Gene_expression of Apoc3 1 0.05 0.93 0
122 INT239410 Regulation of Localization of APOB 1 0.25 0.52 0
123 INT171596 Negative_regulation of Transcription of APOC3 1 0.58 0.42 0
124 INT326524 Negative_regulation of Transcription of APOE 1 0.30 1.71 0
125 INT306793 Negative_regulation of Positive_regulation of APOB 1 0.27 0.33 0
126 INT171593 Positive_regulation of Gene_expression of APOC3 1 0.69 0.55 0
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