GO:0034364

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Name high-density lipoprotein particle
Categary Component
Go Slim No
Go Link GO:0034364
Unique Molecular Interactions 227
Total Molecular Interactions 359
Total Single Events 2348
Pain Genes Associated 31

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for high-density lipoprotein particle. They are ordered first by their pain relevance and then by number of times they were reported for high-density lipoprotein particle. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT297332 Apoe Negative_regulation of Gene_expression of Mpz 1 0.02 1.09 0.87
2 INT208354 Binding of Apoe and Hdl1 12 0.13 8.37 0.77
3 INT178334 Binding of Pon1 and Chdh 1 0.11 11.45 0.66
4 INT297344 Apoe Regulation of Binding of Alms1 1 0.08 1.1 0.61
5 INT297340 Apoe Regulation of Binding of Smo 1 0.10 1.1 0.6
6 INT207440 Binding of HDLBP and PLA2G7 1 0.06 1.25 0.58
7 INT297331 Apoe Negative_regulation of Gene_expression of Il6 1 0.14 0.61 0.57
8 INT222183 Binding of HDLBP and PLA2G15 1 0.01 0.7 0.57
9 INT254761 Igh-Dex Positive_regulation of Apoe 1 0.00 0.08 0.52
10 INT116862 Apoe Positive_regulation of Il10 1 0.30 0.69 0.5
11 INT116863 Apoe Negative_regulation of Hand1 1 0.37 0.69 0.5
12 INT254768 DNMT1 Positive_regulation of Gene_expression of Apoe 1 0.02 0.05 0.49
13 INT197496 Binding of Apoe and Lrp1 4 0.22 2.32 0.46
14 INT307781 Apoa1 Positive_regulation of LCAT 1 0.76 1.19 0.45
15 INT142608 Apoe Regulation of Gene_expression of Il6 1 0.25 1.01 0.44
16 INT213027 Binding of Apoa1 and Scarb1 6 0.09 7.52 0.43
17 INT307780 Apoa1 Positive_regulation of Soat1 1 0.04 1.14 0.42
18 INT254760 Igh-Dex Positive_regulation of Gene_expression of Apoe 1 0.00 0 0.42
19 INT329085 Csf2 Positive_regulation of Apoe 1 0.00 1.23 0.42
20 INT216881 Binding of Apoc4 and Hmox1 1 0.01 1.78 0.4
21 INT122049 Binding of HSD11B1 and Lcat 1 0.21 0.83 0.31
22 INT109098 Binding of ABL2 and PON1 1 0.36 1.32 0.28
23 INT254759 Igh-Dex Positive_regulation of Localization of Apoe 1 0.00 0.32 0.28
24 INT254769 Binding of LDLR and Apoe 1 0.03 0 0.28
25 INT297338 Apoe Regulation of Gnb5 1 0.06 1.12 0.27
26 INT213029 Positive_regulation of Binding of Apoa1 and Scarb1 1 0.09 3.38 0.27
27 INT312768 Pon1 Negative_regulation of Gene_expression of Ccl2 1 0.06 1.42 0.26
28 INT216880 Apoc4 Positive_regulation of Hmox1 1 0.03 1.06 0.25
29 INT307207 Ppara Positive_regulation of Apoa2 1 0.10 0.94 0.25
30 INT254772 DNMT1 Positive_regulation of Apoe 1 0.02 0 0.25
31 INT78293 Binding of Apoe and Ldlr 1 0.20 0.25 0.24
32 INT78295 Binding of Ptpra and Apoe 1 0.42 0.25 0.24
33 INT297334 Gnb5 Regulation of Apoe 1 0.09 0.83 0.24
34 INT239337 Abca1 Positive_regulation of RCT 1 0.07 3.11 0.24
35 INT78294 Negative_regulation of Binding of Ptpra and Apoe 1 0.48 0.25 0.24
36 INT254773 PPARA Positive_regulation of Gene_expression of Apoe 1 0.01 0.07 0.24
37 INT78292 Negative_regulation of Binding of Apoe and Ldlr 1 0.23 0.25 0.24
38 INT305798 Binding of APOA1 and OxP-11D 1 0.02 0.45 0.23
39 INT254774 DNMT1 Positive_regulation of Localization of Apoe 1 0.01 0.31 0.23
40 INT283857 APOA5 Positive_regulation of Positive_regulation of MAPK1 1 0.00 0.6 0.22
41 INT216883 Apoc4 Positive_regulation of TFAM 1 0.00 0.93 0.22
42 INT283858 Binding of PTK2 and APOA5 1 0.00 0.67 0.21
43 INT283860 APOA5 Negative_regulation of MAPK1 1 0.00 0.59 0.21
44 INT189321 Binding of Apoa1 and Hdlcl1 1 0.00 0.68 0.2
45 INT134494 Binding of APOE and Alb 1 0.11 0.45 0.2
46 INT300193 Binding of APOA1 and INSL4 1 0.01 2.17 0.18
47 INT239316 Nr1h2 Positive_regulation of Transcription of Abca1 1 0.15 0.67 0.18
48 INT47344 CPZ Negative_regulation of LCAT 1 0.29 0 0.18
49 INT208360 Binding of Abca1 and Apoe 1 0.15 0.74 0.17
50 INT197499 Binding of Apoe and Tfrc 1 0.14 1.54 0.17
51 INT122528 Apoe Regulation of Eno2 1 0.05 0.29 0.16
52 INT122529 Apoe Regulation of S100B 1 0.18 0.29 0.16
53 INT43510 Apoa2 Positive_regulation of Localization of POMC 1 0.03 0 0.16
54 INT297345 Apoe Negative_regulation of Csf2 1 0.17 0.66 0.16
55 INT329850 APOA5 Negative_regulation of Transcription of APOC3 1 0.24 0.85 0.15
56 INT312794 Hdl1 Regulation of Pon1 1 0.02 1.63 0.15
57 INT344710 Lipc Positive_regulation of Positive_regulation of Hdl1 1 0.04 0.87 0.14
58 INT239355 Binding of Nr1h2 and Positive_regulation of Gene_expression of CETP 1 0.17 3.75 0.14
59 INT297333 Apoe Negative_regulation of Positive_regulation of Tlr4 1 0.10 1.02 0.14
60 INT297343 Binding of Apoe and Tlr4 1 0.09 0.94 0.14
61 INT297339 Tlr4 Negative_regulation of Gene_expression of Apoe 1 0.10 0.73 0.13
62 INT344706 Nr1h2 Regulation of Abca1 1 0.03 2.39 0.12
63 INT33752 Apoa2 Regulation of Localization of POMC 1 0.06 0 0.12
64 INT33750 Apoa2 Regulation of Agt 1 0.07 0 0.12
65 INT33751 Apoa2 Positive_regulation of Positive_regulation of POMC 1 0.09 0 0.11
66 INT2458 Apoa2 Positive_regulation of Localization of Avp 1 0.10 0 0.11
67 INT213042 Apoa1 Positive_regulation of Nos3 1 0.10 2.17 0.11
68 INT204882 gr Negative_regulation of Saa3 1 0.07 0.15 0.11
69 INT312792 Binding of Pon1 and Hdl1 1 0.04 1.85 0.11
70 INT208361 Positive_regulation of Binding of Apoe and Hdl1 1 0.12 1.22 0.1
71 INT297346 Apoe Negative_regulation of Localization of TNF 1 0.48 0.26 0.1
72 INT305780 Binding of APOA1 and LRCH2 1 0.00 0.19 0.1
73 INT282094 Apoa2 Negative_regulation of BCL2 1 0.06 1.15 0.09
74 INT300192 Gene_expression of APOA1 Positive_regulation of HSD11B1 1 0.16 1.08 0.08
75 INT205135 Binding of APOE and APP 1 0.05 0.35 0.08
76 INT208362 Binding of Apoc4 and Hdl1 1 0.00 2.4 0.08
77 INT43121 Apoa2 Regulation of Smc1b 1 0.02 0 0.08
78 INT300641 Binding of APOE and CRP 1 0.41 0.81 0.07
79 INT297330 Apoe Positive_regulation of Gene_expression of Nos2 1 0.26 0.34 0.07
80 INT190885 Binding of Apoa2 and Hdl1 1 0.02 0.73 0.07
81 INT239346 Olfr642 Positive_regulation of Lcat 1 0.00 1.06 0.07
82 INT308665 Binding of Apoe and Gopc 1 0.02 0.49 0.07
83 INT308663 Apoe Regulation of Car2 1 0.02 0.44 0.07
84 INT279652 PPARA Positive_regulation of Gene_expression of Apoa1 1 0.00 0.75 0.07
85 INT50078 Binding of APOE and NPPA 1 0.30 0.42 0.07
86 INT326067 APOA1 Positive_regulation of Localization of APOE 1 0.61 4.22 0.07
87 INT262175 Nr1i2 Positive_regulation of Gene_expression of Abca1 1 0.24 0.21 0.06
88 INT239327 Positive_regulation of Binding of Lcat and Hdl1 1 0.06 1.52 0.06
89 INT239331 RCT Positive_regulation of Lcat 1 0.08 1.08 0.06
90 INT239354 CETP Positive_regulation of Lcat 1 0.28 1.09 0.06
91 INT239326 Binding of Lcat and Hdl1 1 0.05 1.52 0.06
92 INT335047 PPARA Positive_regulation of Gene_expression of APOA1 1 0.20 0.42 0.05
93 INT239348 Binding of Apoa1 and Hdl1 1 0.03 3.34 0.05
94 INT350823 Binding of SAA1 and SELS 1 0.17 2.75 0.05
95 INT296023 Positive_regulation of Apoa2 Negative_regulation of APOA1 1 0.50 0.35 0.05
96 INT296024 Apoa2 Negative_regulation of CETP 1 0.39 0.35 0.05
97 INT290182 Binding of CETP and PLTP 1 0.26 3.31 0.05
98 INT251468 Binding of APOE and DBT 1 0.03 1.18 0.05
99 INT43124 Apoa2 Positive_regulation of Positive_regulation of NA 1 0.07 0 0.05
100 INT296025 Apoa2 Negative_regulation of APOA1 1 0.47 0.35 0.05
101 INT208353 Binding of Apoc4 and Apoc3 1 0.00 2.56 0.04
102 INT236722 Ppara Positive_regulation of Binding of Apoa1 1 0.10 0.18 0.04
103 INT208356 Hdl1 Positive_regulation of Apoe 1 0.12 1.25 0.04
104 INT235551 Gene_expression of Hras1 Negative_regulation of Positive_regulation of Apoe 1 0.03 0.57 0.04
105 INT291751 ALDOA Positive_regulation of PON1 1 0.01 0 0.04
106 INT208357 Hdl1 Positive_regulation of Localization of Apoe 1 0.12 1.26 0.04
107 INT288908 Apoa1 Positive_regulation of Gene_expression of HSD11B1 1 0.03 0.53 0.04
108 INT325025 Apoa2 Positive_regulation of Hdl1 1 0.05 1.03 0.04
109 INT208350 Positive_regulation of Hdl1 Positive_regulation of Apoe 1 0.12 1.27 0.04
110 INT290181 Binding of APOE and PLTP 1 0.17 1.61 0.04
111 INT247439 Binding of APOA1 and HSD11B1 3 0.32 5.01 0.03
112 INT251963 Binding of HSD11B1 and LIPC 1 0.15 0.35 0.03
113 INT194483 Binding of Apoe and Chol1 1 0.24 0.51 0.03
114 INT208352 Apoe Regulation of Localization of Em 1 0.04 1.15 0.03
115 INT194481 Binding of Apoe and Apob 1 0.07 0.51 0.03
116 INT239345 Apoa1 Positive_regulation of RCT 1 0.02 1.15 0.03
117 INT308658 Binding of Apoa2 and Apoe 1 0.17 0.15 0.03
118 INT239351 Binding of CETP and Ldlr 1 0.15 1.01 0.03
119 INT170210 Binding of CETP and HSD11B1 1 0.17 2.58 0
120 INT341487 Binding of APOE and TLR2 1 0.00 0.3 0
121 INT10903 Apoa2 Positive_regulation of Nppb 1 0.08 0.17 0
122 INT104540 FOXG1 Regulation of Lipc 1 0.02 0 0
123 INT239332 Hdl1 Positive_regulation of Gene_expression of Apoa1 1 0.04 0.84 0
124 INT239325 Eef1a2 Negative_regulation of Lipc 1 0.11 0.84 0
125 INT297560 Binding of HSD11B1 and APOL1 1 0.04 0.88 0
126 INT326065 APOE Positive_regulation of LCAT 1 0.53 0.84 0
127 INT344266 Binding of APOH and CD40LG 1 0.04 0.31 0
128 INT352793 Binding of APOC1 and FGF21 1 0.01 2.76 0
129 INT214472 Binding of LPL and GPIHBP1 1 0.29 1.17 0
130 INT88766 Binding of LIPC and CASZ1 1 0.03 0 0
131 INT47454 ras Positive_regulation of Apoa2 1 0.12 0.21 0
132 INT209987 Binding of APOE and LDLR 1 0.24 0 0
133 INT220901 Regulation of Binding of Saa1 and Cd40 1 0.04 0.36 0
134 INT247444 Binding of APOA1 and APOC3 1 0.28 0.39 0
135 INT208349 Regulation of Binding of Apoc3 and Apoe 1 0.01 0.38 0
136 INT10907 Apoa2 Positive_regulation of Localization of Nppb 1 0.09 0.23 0
137 INT213017 Apoa1 Negative_regulation of Positive_regulation of Gtf3a 1 0.00 1.16 0
138 INT326061 Binding of HSD11B1 and LCAT 1 0.11 0.89 0
139 INT350822 SELS Positive_regulation of Gene_expression of SAA1 1 0.21 0.87 0
140 INT247436 Binding of APOA1 and SACM1L 1 0.27 0.39 0
141 INT90283 Binding of APOE and Il1a 1 0.01 0 0
142 INT239341 Binding of Abca1 and Hdl1 1 0.04 4.78 0
143 INT290193 Binding of APOA1 and Hdl1 1 0.01 1 0
144 INT197725 Negative_regulation of CETP Positive_regulation of Positive_regulation of HSD11B1 1 0.11 1.15 0
145 INT201080 Binding of APOE and HLA-C 1 0.41 0.31 0
146 INT283865 Binding of MAPK1 and APOA5 1 0.00 0.22 0
147 INT353802 Binding of APOE and Apob 1 0.05 0.83 0
148 INT197726 Negative_regulation of CETP Positive_regulation of HSD11B1 1 0.11 0.76 0
149 INT170213 CETP Positive_regulation of Gene_expression of HSD11B1 1 0.21 1.49 0
150 INT283866 Binding of SVIL and APOA5 1 0.00 0.22 0
151 INT208355 Binding of Apoc3 and Apoe 1 0.01 0.76 0
152 INT239353 CETP Regulation of Apoa1 1 0.16 0.65 0
153 INT302584 Binding of Lpl and Apoa5 1 0.20 0.63 0
154 INT198933 Binding of Apoe and App 1 0.33 0.19 0
155 INT239342 Lcat Regulation of Apoa1 1 0.16 0.65 0
156 INT353801 Binding of APOE and Cd320 1 0.22 0.83 0
157 INT170215 CETP Positive_regulation of HSD11B1 1 0.26 1.35 0
158 INT326060 Binding of ABCA1 and APOA1 1 0.39 1.5 0
159 INT250152 Binding of APOE and UBE4B 1 0.21 1.2 0
160 INT326058 Negative_regulation of PRKCA Negative_regulation of APOA1 1 0.15 0.32 0
161 INT326059 APOA1 Positive_regulation of Gene_expression of APOE 1 0.61 0.38 0
162 INT302594 Binding of CETP and Apoa5 1 0.26 0.63 0
163 INT326064 APOA1 Positive_regulation of HMGCR 1 0.16 0.19 0
164 INT217396 Binding of Abca1 and App 1 0.26 0.83 0
165 INT213043 Regulation of Binding of Apoa1 and Scarb1 1 0.05 1.12 0
166 INT344712 Nr1h3 Regulation of Abca1 1 0.03 1.68 0
167 INT330530 Binding of PON1 and CIMT 1 0.14 1.48 0
168 INT239321 Binding of Abca1 and Apoa1 1 0.11 1.61 0
169 INT239319 Pltp Regulation of Apoa1 1 0.22 0.65 0
170 INT353804 Binding of APOE and Ldlr 1 0.16 0.84 0
171 INT326057 APOA1 Regulation of Localization of APOE 1 0.54 1.36 0
172 INT300197 Binding of APOA1 and C1S 1 0.39 3.56 0
173 INT239350 Eef1a2 Positive_regulation of Apoa1 1 0.22 0.86 0
174 INT201082 Binding of APOE and HLA-B 1 0.54 1.54 0
175 INT291755 ALDOA Negative_regulation of PON1 1 0.00 0 0
176 INT220908 Binding of Saa1 and Cd40 1 0.04 0.36 0
177 INT302595 Binding of Apoa5 and HDLCQ1 1 0.02 0.16 0
178 INT247440 Binding of APOA1 and APOB 1 0.28 1.02 0
179 INT297558 Binding of APOL1 and SRA1 1 0.22 0.56 0
180 INT284093 VWF Negative_regulation of APOE 1 0.40 2.32 0
181 INT304270 Binding of Apoa1 and Scarb1 1 0.00 0.39 0
182 INT185161 Binding of APOA2 and Retn 1 0.03 1.01 0
183 INT302586 Binding of Lipc and Apoa5 1 0.26 0.63 0
184 INT312769 Binding of Apoe and Pon1 1 0.04 0.86 0
185 INT326066 APOA1 Positive_regulation of Positive_regulation of HMGCR 1 0.17 0.19 0
186 INT353803 Binding of APOE and Hdl1 1 0.01 0.83 0
187 INT131787 Binding of Myo5a and Pon1 1 0.02 0.06 0
188 INT303845 Binding of PON1 and Pon1 1 0.01 1.33 0
189 INT295499 Lcat Regulation of Transcription of Hmgcr 1 0.04 0.2 0
190 INT283899 Binding of Ephb2 and APOA5 1 0.00 0.67 0
191 INT170237 Lpl Regulation of CETP 1 0.02 0.99 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for high-density lipoprotein particle. They are ordered first by their pain relevance and then by number of times they were reported in high-density lipoprotein particle. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT116861 Gene_expression of Apoe 182 0.78 100.41 27.26
2 INT25152 Gene_expression of SAA1 37 0.75 53.56 8.07
3 INT8579 Gene_expression of Apoa1 13 0.76 35.89 7.21
4 INT197493 Localization of Apoe 61 0.79 27.48 7.06
5 INT142264 Positive_regulation of Apoe 47 0.50 26.35 6.94
6 INT19146 Negative_regulation of Apoa2 19 0.36 5.34 6.73
7 INT182351 Positive_regulation of Gene_expression of Apoe 38 0.50 19.78 6.72
8 INT63042 Binding of Apoe 59 0.48 31.23 5.88
9 INT74614 Positive_regulation of Apoa1 16 0.68 23.95 5.04
10 INT55758 Positive_regulation of Apoe 15 0.70 11.71 4.69
11 INT3128 Negative_regulation of PON1 30 0.59 26.19 4.57
12 INT181886 Gene_expression of Apoa1 40 0.64 40.53 4.56
13 INT28662 Gene_expression of PON1 19 0.65 16.46 4.49
14 INT45975 Positive_regulation of SAA1 17 0.67 19.7 4.15
15 INT2453 Positive_regulation of Apoa2 20 0.54 3.49 4.08
16 INT15033 Gene_expression of Apoe 18 0.78 14.97 3.75
17 INT25464 Binding of SAA1 11 0.42 6.89 3.72
18 INT104624 Negative_regulation of Apoe 26 0.59 19.25 3.71
19 INT52047 Gene_expression of APOE 50 0.78 34.75 3.52
20 INT72141 Binding of Apoe 11 0.37 10.91 3.27
21 INT97710 Localization of Apoe 1 0.79 7.18 3.2
22 INT44873 Negative_regulation of LCAT 16 0.59 6.92 3.13
23 INT198888 Gene_expression of Apoc4 12 0.27 5.44 3.09
24 INT10830 Regulation of Apoa1 11 0.44 15.1 3.04
25 INT597 Positive_regulation of PON1 26 0.62 19.14 2.87
26 INT10556 Regulation of Apoa2 5 0.44 0.51 2.8
27 INT49759 Negative_regulation of CETP 43 0.58 52 2.68
28 INT50080 Binding of APOE 38 0.45 29.61 2.67
29 INT21712 Positive_regulation of APOA1 32 0.67 21.64 2.64
30 INT97713 Negative_regulation of Apoe 4 0.59 4.57 2.52
31 INT190081 Gene_expression of Abca1 21 0.65 18.18 2.45
32 INT181880 Positive_regulation of Apoa1 19 0.66 21.19 2.43
33 INT2452 Localization of Apoa2 9 0.55 0 2.3
34 INT208344 Positive_regulation of Localization of Apoe 22 0.48 9.6 2.27
35 INT142265 Regulation of Apoe 20 0.60 9.52 2.23
36 INT3723 Binding of PON1 9 0.46 5.83 2.13
37 INT15765 Localization of PON1 8 0.75 3.61 2.08
38 INT84060 Regulation of Apoe 4 0.62 3.33 2.05
39 INT49313 Positive_regulation of Gene_expression of Apoa1 3 0.68 9.55 2.01
40 INT22863 Negative_regulation of Apoa1 10 0.57 10.68 1.86
41 INT21813 Gene_expression of Apoa2 10 0.61 3.68 1.81
42 INT72676 Gene_expression of APOA1 34 0.75 34.15 1.67
43 INT156484 Binding of Apoa1 4 0.47 6.78 1.63
44 INT96814 Negative_regulation of APOE 13 0.59 10.64 1.61
45 INT181881 Positive_regulation of Gene_expression of Apoa1 13 0.48 14.31 1.45
46 INT192762 Localization of SAA1 10 0.78 12.63 1.44
47 INT217388 Negative_regulation of Gene_expression of Apoe 11 0.59 6.07 1.4
48 INT181882 Localization of Apoa1 8 0.71 7.94 1.37
49 INT97716 Transcription of Apoe 3 0.53 2.61 1.36
50 INT101653 Negative_regulation of SAA1 7 0.39 7 1.33
51 INT118817 Positive_regulation of Apoc4 6 0.45 6.44 1.23
52 INT97715 Regulation of Gene_expression of Apoe 3 0.62 1.98 1.23
53 INT113336 Positive_regulation of Gene_expression of Apoe 3 0.70 1.79 1.23
54 INT124218 Gene_expression of Pon1 9 0.75 19.55 1.19
55 INT140288 Localization of Pon1 4 0.78 6.15 1.15
56 INT181879 Negative_regulation of Apoa1 8 0.55 8.18 1.11
57 INT239302 Positive_regulation of Gene_expression of Abca1 9 0.32 9.1 1.06
58 INT217390 Negative_regulation of Positive_regulation of Apoe 3 0.37 1.95 1.05
59 INT44874 Regulation of LCAT 1 0.62 0.15 1
60 INT52113 Gene_expression of CETP 25 0.69 25.71 0.99
61 INT124220 Binding of Pon1 9 0.47 7.84 0.99
62 INT97714 Negative_regulation of Localization of Apoe 1 0.58 1.83 0.97
63 INT180451 Positive_regulation of Apoa2 15 0.67 12.65 0.89
64 INT72672 Positive_regulation of Gene_expression of APOA1 4 0.67 3.81 0.89
65 INT181885 Binding of Apoa1 7 0.35 5.66 0.84
66 INT190089 Binding of Abca1 5 0.36 2.21 0.83
67 INT192761 Positive_regulation of Gene_expression of SAA1 5 0.40 7.45 0.82
68 INT142597 Regulation of Binding of Apoe 1 0.34 2.21 0.8
69 INT197495 Negative_regulation of Localization of Apoe 6 0.43 2.19 0.73
70 INT44612 Positive_regulation of APOE 16 0.67 5.73 0.72
71 INT303837 Negative_regulation of Pon1 4 0.57 11.08 0.71
72 INT270428 Negative_regulation of Binding of APOE 2 0.41 1.16 0.7
73 INT113335 Regulation of Transcription of Apoe 1 0.27 0.51 0.7
74 INT25374 Negative_regulation of Negative_regulation of Apoa2 1 0.30 0.24 0.67
75 INT83194 Binding of APOH 4 0.17 3.92 0.66
76 INT175580 Localization of APOE 10 0.76 18.84 0.65
77 INT48137 Gene_expression of Saa1 3 0.61 4.36 0.63
78 INT97708 Regulation of Localization of Apoe 1 0.61 2.06 0.62
79 INT181888 Regulation of Apoa1 5 0.26 5.07 0.6
80 INT213118 Negative_regulation of Gene_expression of Apoa1 2 0.42 2.86 0.6
81 INT45724 Positive_regulation of Lipc 2 0.08 0.84 0.58
82 INT113334 Positive_regulation of Positive_regulation of Apoe 1 0.50 0.6 0.56
83 INT219610 Protein_catabolism of SAA1 2 0.90 4.47 0.54
84 INT200980 Transcription of APOL1 1 0.67 0.84 0.54
85 INT192765 Negative_regulation of Gene_expression of SAA1 1 0.34 4.55 0.54
86 INT201005 Gene_expression of APOL1 9 0.75 4.66 0.53
87 INT77258 Regulation of SAA1 4 0.54 1.93 0.53
88 INT10983 Binding of Apoa2 7 0.45 4.21 0.52
89 INT20239 Regulation of APOA1 10 0.60 10.98 0.51
90 INT239247 Positive_regulation of APOA5 7 0.37 3.68 0.51
91 INT197322 Protein_catabolism of Apoe 6 0.71 3.52 0.51
92 INT186862 Regulation of Pon1 5 0.60 6.15 0.51
93 INT46311 Regulation of Gene_expression of SAA1 4 0.27 1.51 0.51
94 INT217370 Phosphorylation of Apoe 2 0.63 1.8 0.49
95 INT240765 Positive_regulation of Pon1 16 0.67 12.06 0.48
96 INT43397 Positive_regulation of Localization of Apoa2 1 0.09 0 0.48
97 INT2638 Regulation of PON1 5 0.59 5.13 0.45
98 INT96816 Regulation of APOE 8 0.45 6.62 0.44
99 INT190882 Regulation of Gene_expression of Apoa1 4 0.23 3.67 0.43
100 INT133379 Negative_regulation of APOH 1 0.07 0.09 0.42
101 INT174753 Gene_expression of Apoa2 15 0.75 13.82 0.41
102 INT122047 Positive_regulation of Lcat 3 0.35 1.94 0.4
103 INT97712 Negative_regulation of Transcription of Apoe 1 0.43 1.05 0.4
104 INT190691 Negative_regulation of APOA1 12 0.42 15.9 0.39
105 INT179360 Positive_regulation of HDLBP 5 0.11 5.09 0.39
106 INT181883 Negative_regulation of Negative_regulation of Apoa1 1 0.40 1.24 0.39
107 INT278301 Gene_expression of HDLBP 2 0.08 3.09 0.37
108 INT116725 Positive_regulation of CETP 19 0.49 16.33 0.36
109 INT72673 Transcription of APOA1 2 0.52 1.2 0.36
110 INT81221 Positive_regulation of APOH 1 0.02 1.24 0.36
111 INT131542 Negative_regulation of Gene_expression of APOE 6 0.40 3.92 0.33
112 INT261209 Localization of Apoa1 4 0.73 2.61 0.33
113 INT130344 Gene_expression of APOH 3 0.34 2.87 0.32
114 INT239295 Positive_regulation of Abca1 3 0.30 2.18 0.32
115 INT47453 Positive_regulation of Positive_regulation of Apoa2 3 0.31 1.17 0.32
116 INT307779 Positive_regulation of Localization of Apoa1 1 0.49 0.88 0.31
117 INT312778 Positive_regulation of Gene_expression of Pon1 1 0.67 2.37 0.31
118 INT83195 Regulation of Binding of APOH 1 0.13 0.88 0.31
119 INT189968 Binding of APOA1 12 0.47 10.1 0.3
120 INT208346 Binding of Apoc4 5 0.03 3.78 0.3
121 INT311128 Positive_regulation of Regulation of Apoe 1 0.30 0.3 0.3
122 INT43396 Regulation of Localization of Apoa2 1 0.09 0 0.3
123 INT175687 Transcription of Apoe 4 0.72 2.12 0.29
124 INT96815 Regulation of Gene_expression of APOE 2 0.62 1.1 0.29
125 INT258074 Negative_regulation of HDLBP 2 0.06 2.76 0.28
126 INT178326 Gene_expression of Pon1 1 0.67 2.93 0.28
127 INT88770 Negative_regulation of LIPC 1 0.37 0.17 0.28
128 INT325017 Localization of Pon1 1 0.46 1.37 0.28
129 INT178329 Negative_regulation of Gene_expression of Pon1 1 0.43 0.93 0.28
130 INT297322 Binding of Apoa2 3 0.36 1.7 0.27
131 INT66978 Binding of Pon1 2 0.48 6.13 0.27
132 INT97711 Positive_regulation of Transcription of Apoe 1 0.46 1.06 0.27
133 INT239279 Regulation of Gene_expression of Abca1 2 0.44 2.42 0.26
134 INT254756 Regulation of Positive_regulation of Apoe 1 0.20 0.22 0.26
135 INT344685 Positive_regulation of Binding of Abca1 1 0.12 0.76 0.26
136 INT200986 Positive_regulation of Gene_expression of APOL1 1 0.36 0.26 0.26
137 INT67227 Positive_regulation of Binding of Apoa2 2 0.26 1.31 0.25
138 INT47525 Positive_regulation of Binding of PON1 1 0.43 0 0.25
139 INT355261 Positive_regulation of Saa3 1 0.31 5.37 0.25
140 INT2450 Negative_regulation of Positive_regulation of Apoa2 1 0.21 0 0.24
141 INT200997 Regulation of Transcription of APOL1 1 0.32 0.23 0.24
142 INT201019 Localization of APOL1 3 0.66 1.29 0.23
143 INT116724 Positive_regulation of Gene_expression of CETP 3 0.41 7.92 0.23
144 INT247452 Gene_expression of APOA5 4 0.54 5.71 0.22
145 INT151855 Negative_regulation of Negative_regulation of PON1 2 0.38 2.39 0.22
146 INT178328 Positive_regulation of Pon1 2 0.50 2.2 0.22
147 INT2449 Negative_regulation of Localization of Apoa2 1 0.19 0 0.22
148 INT192763 Transcription of SAA1 1 0.57 1.73 0.22
149 INT283891 Positive_regulation of Gene_expression of APOA5 1 0.01 1.36 0.22
150 INT323964 Negative_regulation of Binding of Apoe 1 0.39 0.35 0.22
151 INT323965 Protein_catabolism of Apoa2 1 0.01 0.34 0.22
152 INT70647 Regulation of CETP 7 0.61 4.53 0.21
153 INT175691 Gene_expression of Lcat 6 0.57 7.87 0.21
154 INT198892 Regulation of Binding of Apoe 6 0.45 2.94 0.21
155 INT208337 Positive_regulation of Gene_expression of Apoc4 2 0.03 1.22 0.21
156 INT239287 Transcription of Abca1 1 0.32 1.87 0.21
157 INT180454 Negative_regulation of Apoa2 6 0.42 7.42 0.2
158 INT45473 Positive_regulation of LIPC 3 0.20 5.49 0.2
159 INT283877 Localization of APOA5 3 0.27 1.48 0.2
160 INT193810 Phosphorylation of APOE 2 0.27 1.13 0.2
161 INT190874 Negative_regulation of Gene_expression of Apoa1 1 0.15 0.9 0.2
162 INT274466 Positive_regulation of Saa1 1 0.37 1.77 0.2
163 INT10984 Negative_regulation of Binding of Apoa2 2 0.35 0.7 0.19
164 INT239308 Positive_regulation of Transcription of Abca1 1 0.28 0.67 0.18
165 INT312781 Protein_catabolism of Pon1 1 0.97 1.01 0.18
166 INT158693 Regulation of HDLBP 1 0.01 1.02 0.18
167 INT297897 Positive_regulation of Localization of PON1 1 0.50 0.23 0.18
168 INT239275 Regulation of Localization of Apoa1 1 0.19 1.62 0.18
169 INT67225 Positive_regulation of Gene_expression of Apoa2 2 0.28 1.3 0.17
170 INT282717 Regulation of Saa3 1 0.23 0.28 0.17
171 INT254754 Regulation of Localization of Apoe 1 0.20 0.39 0.17
172 INT254755 Positive_regulation of Transcription of Apoe 1 0.16 0.41 0.16
173 INT297577 Localization of APOA1 12 0.65 4.58 0.15
174 INT217387 Regulation of Abca1 3 0.27 2.01 0.15
175 INT252219 Negative_regulation of Binding of Apoa1 1 0.16 0.95 0.15
176 INT200973 Negative_regulation of APOL1 1 0.14 0.18 0.15
177 INT96772 Positive_regulation of Gene_expression of APOE 5 0.66 5.44 0.14
178 INT39694 Regulation of LIPC 2 0.58 0.89 0.14
179 INT198894 Regulation of Gene_expression of Apoe 2 0.44 0.56 0.14
180 INT126804 Gene_expression of APOC1 1 0.75 1.06 0.14
181 INT48136 Positive_regulation of Gene_expression of Saa1 1 0.54 1.03 0.14
182 INT265905 Regulation of Localization of SAA1 1 0.60 1 0.14
183 INT104623 Regulation of Negative_regulation of Apoe 2 0.45 0.73 0.12
184 INT3442 Negative_regulation of Lcat 2 0.42 4.36 0.12
185 INT239288 Binding of Lcat 1 0.27 2.59 0.12
186 INT264861 Regulation of Apoa2 5 0.44 4.25 0.11
187 INT93878 Positive_regulation of Lipc 4 0.47 3.09 0.11
188 INT190693 Negative_regulation of Regulation of APOA1 1 0.09 1.94 0.11
189 INT326081 Negative_regulation of Localization of APOE 1 0.56 2.23 0.11
190 INT201000 Positive_regulation of APOL1 2 0.45 0.66 0.1
191 INT279650 Transcription of Apoa2 1 0.02 0.79 0.1
192 INT279651 Positive_regulation of Transcription of Apoa2 1 0.02 0.84 0.1
193 INT200976 Positive_regulation of Transcription of APOL1 1 0.49 0.23 0.1
194 INT180452 Localization of Apoa2 2 0.73 2.83 0.09
195 INT308634 Localization of Apoc4 1 0.01 0.42 0.09
196 INT127244 Binding of APOL1 1 0.33 3.29 0.09
197 INT300643 Positive_regulation of Binding of APOE 1 0.44 0.8 0.09
198 INT303836 Positive_regulation of Localization of Pon1 1 0.36 1.07 0.09
199 INT268708 Phosphorylation of APOC1 1 0.38 1.02 0.09
200 INT303841 Negative_regulation of Gene_expression of Pon1 1 0.31 0.9 0.09
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