GO:0034374

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Name low-density lipoprotein particle remodeling
Categary Process
Go Slim No
Go Link GO:0034374
Unique Molecular Interactions 346
Total Molecular Interactions 459
Total Single Events 5092
Pain Genes Associated 21

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for low-density lipoprotein particle remodeling. They are ordered first by their pain relevance and then by number of times they were reported for low-density lipoprotein particle remodeling. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT150632 Ea1 Negative_regulation of Mpo 1 0.17 1.55 2.9
2 INT14991 SFTPA1 Positive_regulation of Localization of MPO 1 0.11 1.65 1.92
3 INT108409 AGT Positive_regulation of AGTR2 2 0.31 1.49 1.11
4 INT207437 Binding of PLA2G7 and ERAL1 1 0.14 3.64 1.11
5 INT112163 Calca Positive_regulation of Mpo 1 0.49 1.23 1
6 INT34457 AGT Positive_regulation of POMC 1 0.01 0 0.91
7 INT185417 Binding of ALOX5 and PLA2G2A 4 0.16 3.13 0.9
8 INT297332 Apoe Negative_regulation of Gene_expression of Mpz 1 0.02 1.09 0.87
9 INT34458 AGT Negative_regulation of PENK 1 0.00 0 0.81
10 INT127383 Neo1 Regulation of Localization of Mpo 1 0.14 0.7 0.79
11 INT117604 AKR1C1 Negative_regulation of Positive_regulation of Mpo 1 0.00 1.45 0.78
12 INT208354 Binding of Apoe and Hdl1 12 0.13 8.37 0.77
13 INT123556 Shfm1 Regulation of Mpo 1 0.09 0.88 0.76
14 INT158607 Ns5atp9 Positive_regulation of Mpo 1 0.35 1.85 0.75
15 INT109718 Tac1 Negative_regulation of Mpo 1 0.25 0.81 0.67
16 INT109717 Calca Negative_regulation of Mpo 1 0.16 0.8 0.67
17 INT113780 AGT Positive_regulation of Positive_regulation of Nfkb1 1 0.00 1.25 0.64
18 INT297344 Apoe Regulation of Binding of Alms1 1 0.08 1.1 0.61
19 INT297340 Apoe Regulation of Binding of Smo 1 0.10 1.1 0.6
20 INT270099 Negative_regulation of Binding of CPOX and PLA2G2A 1 0.01 0.51 0.59
21 INT270100 Negative_regulation of Binding of ALOX5 and PLA2G2A 1 0.01 0.51 0.59
22 INT270103 Binding of CPOX and PLA2G2A 1 0.01 0.5 0.58
23 INT207440 Binding of HDLBP and PLA2G7 1 0.06 1.25 0.58
24 INT297331 Apoe Negative_regulation of Gene_expression of Il6 1 0.14 0.61 0.57
25 INT270102 ALOX5 Negative_regulation of PLA2G2A 1 0.01 0.49 0.57
26 INT270101 CPOX Negative_regulation of PLA2G2A 1 0.01 0.48 0.56
27 INT131316 Tnf Positive_regulation of Mpo 1 0.29 0.65 0.55
28 INT34459 AGT Negative_regulation of MBTPS1 1 0.01 0 0.54
29 INT132438 Binding of AGT and OXTR 1 0.08 1.03 0.53
30 INT254761 Igh-Dex Positive_regulation of Apoe 1 0.00 0.08 0.52
31 INT271344 MPO Regulation of Protein_catabolism of ACCS 1 0.02 2.42 0.51
32 INT157709 CRX Positive_regulation of Mpo 1 0.08 1.11 0.5
33 INT19296 AGT Positive_regulation of Localization of AVP 1 0.38 0 0.5
34 INT116862 Apoe Positive_regulation of Il10 1 0.30 0.69 0.5
35 INT116863 Apoe Negative_regulation of Hand1 1 0.37 0.69 0.5
36 INT21315 AGT Positive_regulation of Npy 1 0.03 0.15 0.5
37 INT14992 FPR1 Positive_regulation of Localization of MPO 2 0.56 1.1 0.49
38 INT254768 DNMT1 Positive_regulation of Gene_expression of Apoe 1 0.02 0.05 0.49
39 INT354986 Cacna1a Regulation of Localization of Mpo 1 0.01 1.15 0.49
40 INT58633 Negative_regulation of Il1f5 Negative_regulation of Mpo 1 0.15 0.98 0.48
41 INT58634 Negative_regulation of Il1 Negative_regulation of Mpo 1 0.20 0.98 0.47
42 INT197496 Binding of Apoe and Lrp1 4 0.22 2.32 0.46
43 INT342633 ACE Regulation of Gene_expression of AGT 1 0.01 0.14 0.46
44 INT222923 Negative_regulation of Pde4a Negative_regulation of Positive_regulation of Mpo 1 0.04 0.59 0.45
45 INT99160 Binding of Mpo and Nrm 1 0.38 0.92 0.45
46 INT142608 Apoe Regulation of Gene_expression of Il6 1 0.25 1.01 0.44
47 INT114341 Agt Positive_regulation of AGT 3 0.01 1.15 0.43
48 INT345288 AGT Positive_regulation of Localization of CCL2 1 0.01 1.5 0.43
49 INT345291 AGT Positive_regulation of CCL2 1 0.01 1.39 0.43
50 INT254760 Igh-Dex Positive_regulation of Gene_expression of Apoe 1 0.00 0 0.42
51 INT329085 Csf2 Positive_regulation of Apoe 1 0.00 1.23 0.42
52 INT182489 Gene_expression of AGTR2 Positive_regulation of Gene_expression of AGTR1 1 0.26 0.92 0.4
53 INT191493 Binding of AGTR1 and NLRP3 2 0.03 2.35 0.39
54 INT181862 Binding of MPO and PRTN3 2 0.16 1.18 0.38
55 INT240617 Binding of APOB and ADIPOQ 1 0.04 3.62 0.38
56 INT185530 Binding of AGT and EDNRA 1 0.00 0.31 0.38
57 INT158606 Negative_regulation of Ns5atp9 Positive_regulation of Mpo 1 0.30 0.93 0.38
58 INT158608 Positive_regulation of Ns5atp9 Positive_regulation of Mpo 1 0.25 0.93 0.37
59 INT161517 Mpo Positive_regulation of Gene_expression of Il17a 1 0.22 1.42 0.36
60 INT99159 Nrm Positive_regulation of Mpo 1 0.44 0.85 0.36
61 INT230786 Binding of AGT and ACE 4 0.15 2.53 0.34
62 INT138015 Binding of Paf and Positive_regulation of Mpo 1 0.23 0.53 0.33
63 INT138014 Gm2170 Negative_regulation of Positive_regulation of Mpo 1 0.01 0.53 0.32
64 INT72445 Binding of AGT and REN 3 0.34 0.88 0.31
65 INT207434 LPA Regulation of Gene_expression of PLA2G7 1 0.11 0.73 0.31
66 INT271350 MPO Positive_regulation of TIMP1 1 0.05 1.66 0.29
67 INT200631 AGT Positive_regulation of Gene_expression of TGFB1 1 0.06 1.36 0.29
68 INT319753 Mpo Positive_regulation of Timp1 1 0.14 2.13 0.29
69 INT182499 Binding of AGTR1 and AGTR2 3 0.20 2.79 0.28
70 INT288911 AGT Positive_regulation of CYBB 3 0.07 2.96 0.28
71 INT254759 Igh-Dex Positive_regulation of Localization of Apoe 1 0.00 0.32 0.28
72 INT70096 Csrp3 Positive_regulation of Mpo 1 0.10 0.19 0.28
73 INT207436 IL8 Negative_regulation of Gene_expression of PLA2G7 1 0.10 0.9 0.28
74 INT207442 IFNG Negative_regulation of Gene_expression of PLA2G7 1 0.08 0.9 0.28
75 INT254769 Binding of LDLR and Apoe 1 0.03 0 0.28
76 INT207435 IL1B Negative_regulation of Gene_expression of PLA2G7 1 0.07 0.9 0.28
77 INT297338 Apoe Regulation of Gnb5 1 0.06 1.12 0.27
78 INT85531 Rian Negative_regulation of Mpo 1 0.03 1.36 0.27
79 INT141635 Binding of APOB and Alb 1 0.02 0.3 0.26
80 INT207441 Binding of LPA and PLA2G7 1 0.10 0.56 0.26
81 INT156589 Hst1 Negative_regulation of Mpo 1 0.41 0.95 0.26
82 INT342456 AGT Positive_regulation of Gene_expression of CCL2 1 0.07 0.63 0.25
83 INT307207 Ppara Positive_regulation of Apoa2 1 0.10 0.94 0.25
84 INT254772 DNMT1 Positive_regulation of Apoe 1 0.02 0 0.25
85 INT78293 Binding of Apoe and Ldlr 1 0.20 0.25 0.24
86 INT41588 Binding of AGT and Lhb 1 0.00 0 0.24
87 INT78295 Binding of Ptpra and Apoe 1 0.42 0.25 0.24
88 INT41589 Binding of AGT and Prl 1 0.00 0 0.24
89 INT297334 Gnb5 Regulation of Apoe 1 0.09 0.83 0.24
90 INT78294 Negative_regulation of Binding of Ptpra and Apoe 1 0.48 0.25 0.24
91 INT80138 PLA2G2A Positive_regulation of Localization of TBXA2R 1 0.30 0.15 0.24
92 INT254773 PPARA Positive_regulation of Gene_expression of Apoe 1 0.01 0.07 0.24
93 INT78292 Negative_regulation of Binding of Apoe and Ldlr 1 0.23 0.25 0.24
94 INT191492 Binding of AGT and NLRP3 1 0.01 0.35 0.23
95 INT254774 DNMT1 Positive_regulation of Localization of Apoe 1 0.01 0.31 0.23
96 INT277072 Binding of PLA2G7 and Lipg 1 0.00 1.32 0.21
97 INT228703 MPO Regulation of Positive_regulation of CRP 1 0.40 1.63 0.2
98 INT134494 Binding of APOE and Alb 1 0.11 0.45 0.2
99 INT274094 EDN1 Positive_regulation of AGT 1 0.16 0.95 0.2
100 INT258017 Binding of AGT and ANGPT2 3 0.11 2.35 0.19
101 INT273658 Dss1 Positive_regulation of Mpo 1 0.16 0.98 0.19
102 INT348059 Dbi Negative_regulation of Binding of Mpo 1 0.08 0.43 0.19
103 INT2433 Mrf Positive_regulation of Mpo 1 0.33 0.65 0.18
104 INT229223 Binding of AGT and FAS 1 0.08 0.91 0.17
105 INT36568 AGT Positive_regulation of FBF1 1 0.39 0.5 0.17
106 INT208360 Binding of Abca1 and Apoe 1 0.15 0.74 0.17
107 INT197499 Binding of Apoe and Tfrc 1 0.14 1.54 0.17
108 INT233904 NLRP3 Positive_regulation of AGT 1 0.06 0.81 0.17
109 INT229224 Positive_regulation of Binding of AGT and FAS 1 0.09 0.92 0.17
110 INT36567 Negative_regulation of AGT Positive_regulation of FBF1 1 0.36 0.5 0.17
111 INT111863 Negative_regulation of Binding of AGT and LNPEP 1 0.09 0 0.16
112 INT122528 Apoe Regulation of Eno2 1 0.05 0.29 0.16
113 INT122529 Apoe Regulation of S100B 1 0.18 0.29 0.16
114 INT111861 Binding of AGT and LNPEP 1 0.07 0 0.16
115 INT43510 Apoa2 Positive_regulation of Localization of POMC 1 0.03 0 0.16
116 INT297345 Apoe Negative_regulation of Csf2 1 0.17 0.66 0.16
117 INT229421 Atp6v0a2 Negative_regulation of Positive_regulation of Mpo 1 0.03 2.8 0.16
118 INT229422 Atp6v0a2 Regulation of Mpo 1 0.03 3.39 0.15
119 INT347071 Negative_regulation of REN Negative_regulation of Positive_regulation of AGT 1 0.35 0.44 0.14
120 INT34430 AGT Positive_regulation of Localization of POMC 1 0.30 0.31 0.14
121 INT2927 Positive_regulation of Mpo Positive_regulation of Localization of LH 1 0.26 0.28 0.14
122 INT170817 CMA1 Positive_regulation of Gene_expression of AGT 1 0.19 1.41 0.14
123 INT80139 PLA2G2A Positive_regulation of Gene_expression of TBXA2R 1 0.30 0.15 0.14
124 INT344710 Lipc Positive_regulation of Positive_regulation of Hdl1 1 0.04 0.87 0.14
125 INT344946 AGT Regulation of Negative_regulation of ACE 1 0.21 0.61 0.14
126 INT239355 Binding of Nr1h2 and Positive_regulation of Gene_expression of CETP 1 0.17 3.75 0.14
127 INT297333 Apoe Negative_regulation of Positive_regulation of Tlr4 1 0.10 1.02 0.14
128 INT297343 Binding of Apoe and Tlr4 1 0.09 0.94 0.14
129 INT96801 Nxnl1 Negative_regulation of Mpo 1 0.01 0.62 0.13
130 INT297339 Tlr4 Negative_regulation of Gene_expression of Apoe 1 0.10 0.73 0.13
131 INT59808 Binding of AGT and PLCB1 1 0.02 0 0.13
132 INT258016 AGTR1 Positive_regulation of EGFR 1 0.15 1.24 0.13
133 INT59809 AGT Positive_regulation of PLCB1 1 0.03 0 0.13
134 INT5651 Ptger1 Negative_regulation of Positive_regulation of Mpo 1 0.00 0.34 0.13
135 INT59810 ADRA1D Positive_regulation of AGT 1 0.01 0 0.13
136 INT33752 Apoa2 Regulation of Localization of POMC 1 0.06 0 0.12
137 INT344713 Nr1h2 Regulation of Abcg1 1 0.03 2.39 0.12
138 INT33750 Apoa2 Regulation of Agt 1 0.07 0 0.12
139 INT182496 AGT Positive_regulation of Phosphorylation of STAT3 1 0.03 0.79 0.12
140 INT345290 AGT Positive_regulation of NOX1 1 0.00 1.11 0.12
141 INT33751 Apoa2 Positive_regulation of Positive_regulation of POMC 1 0.09 0 0.11
142 INT2458 Apoa2 Positive_regulation of Localization of Avp 1 0.10 0 0.11
143 INT352497 AGT Positive_regulation of Binding of CRS 1 0.14 0.87 0.11
144 INT46469 Mpo Positive_regulation of Localization of LH 1 0.45 0.95 0.1
145 INT208361 Positive_regulation of Binding of Apoe and Hdl1 1 0.12 1.22 0.1
146 INT334893 ACE Negative_regulation of Gene_expression of AGT 1 0.03 1.41 0.1
147 INT336990 Binding of AGTR1 and BDKRB2 1 0.03 0 0.1
148 INT148102 AGT Positive_regulation of Gene_expression of STK24 1 0.37 0.96 0.1
149 INT297346 Apoe Negative_regulation of Localization of TNF 1 0.48 0.26 0.1
150 INT258018 Binding of AGT and RASGRP1 1 0.00 1.59 0.1
151 INT270731 Binding of AGTR1 and ACE 1 0.02 0.67 0.09
152 INT282094 Apoa2 Negative_regulation of BCL2 1 0.06 1.15 0.09
153 INT308585 Binding of APOB and PLA2G7 1 0.07 0.69 0.09
154 INT279707 Positive_regulation of AGTR1 Regulation of TYRP1 1 0.00 0 0.09
155 INT279706 Positive_regulation of AGTR1 Regulation of TRPC6 1 0.00 0 0.09
156 INT254641 CGA Positive_regulation of AGT 1 0.17 1.51 0.08
157 INT303123 Gpt Positive_regulation of Gene_expression of Mpo 1 0.22 0.99 0.08
158 INT271354 MPO Regulation of Gene_expression of CRP 1 0.16 1.74 0.08
159 INT205135 Binding of APOE and APP 1 0.05 0.35 0.08
160 INT303125 Nos2 Positive_regulation of Gene_expression of Mpo 1 0.34 0.99 0.08
161 INT267969 Binding of AGT and TRPV1 1 0.00 0.44 0.08
162 INT267970 Negative_regulation of Binding of AGT and TRPV1 1 0.00 0.44 0.08
163 INT271351 MPO Positive_regulation of CRP 1 0.07 1.69 0.08
164 INT254639 CGA Positive_regulation of Gene_expression of AGT 1 0.18 1.51 0.08
165 INT43121 Apoa2 Regulation of Smc1b 1 0.02 0 0.08
166 INT300641 Binding of APOE and CRP 1 0.41 0.81 0.07
167 INT297330 Apoe Positive_regulation of Gene_expression of Nos2 1 0.26 0.34 0.07
168 INT190885 Binding of Apoa2 and Hdl1 1 0.02 0.73 0.07
169 INT355641 Positive_regulation of MPO Positive_regulation of Gene_expression of ROS1 1 0.24 0.84 0.07
170 INT21446 Ambp Negative_regulation of Positive_regulation of Mpo 1 0.01 0 0.07
171 INT172382 AGT Positive_regulation of Localization of EDN1 1 0.03 0.34 0.07
172 INT281900 Positive_regulation of Binding of AGT and AGTR1 1 0.12 0.16 0.07
173 INT308665 Binding of Apoe and Gopc 1 0.02 0.49 0.07
174 INT308663 Apoe Regulation of Car2 1 0.02 0.44 0.07
175 INT76965 Mpo Negative_regulation of DLD 1 0.26 0.91 0.07
176 INT227353 Binding of Cat and Mpo 1 0.18 0.56 0.07
177 INT50078 Binding of APOE and NPPA 1 0.30 0.42 0.07
178 INT326067 APOA1 Positive_regulation of Localization of APOE 1 0.61 4.22 0.07
179 INT262187 Nr1i2 Positive_regulation of Gene_expression of Abcg1 1 0.24 0.21 0.06
180 INT281909 Binding of AGT and AGTR1 1 0.09 0.16 0.06
181 INT239354 CETP Positive_regulation of Lcat 1 0.28 1.09 0.06
182 INT88773 Positive_regulation of Binding of AGT and Agtrap 1 0.01 0.88 0.05
183 INT255166 Binding of MOCS1 and MPO 1 0.00 0.7 0.05
184 INT296023 Positive_regulation of Apoa2 Negative_regulation of APOA1 1 0.50 0.35 0.05
185 INT296024 Apoa2 Negative_regulation of CETP 1 0.39 0.35 0.05
186 INT290182 Binding of CETP and PLTP 1 0.26 3.31 0.05
187 INT251468 Binding of APOE and DBT 1 0.03 1.18 0.05
188 INT336132 Binding of AGTR1 and ANG 1 0.00 0.38 0.05
189 INT43124 Apoa2 Positive_regulation of Positive_regulation of NA 1 0.07 0 0.05
190 INT296025 Apoa2 Negative_regulation of APOA1 1 0.47 0.35 0.05
191 INT231395 Binding of HSD11B1 and Apob 1 0.27 1.18 0.04
192 INT177350 Binding of CEL and PLA2G2A 1 0.06 0.08 0.04
193 INT208356 Hdl1 Positive_regulation of Apoe 1 0.12 1.25 0.04
194 INT354983 Cacna1a Regulation of Mpo 1 0.02 0.41 0.04
195 INT293899 UPF1 Positive_regulation of Gene_expression of APOB 1 0.01 0 0.04
196 INT235551 Gene_expression of Hras1 Negative_regulation of Positive_regulation of Apoe 1 0.03 0.57 0.04
197 INT240623 Binding of CRP and Apob 1 0.01 0.52 0.04
198 INT290180 Binding of APOB and PLTP 1 0.19 0.6 0.04
199 INT208357 Hdl1 Positive_regulation of Localization of Apoe 1 0.12 1.26 0.04
200 INT258020 Binding of AGTR1 and ANGPT2 1 0.03 0.29 0.04

Single Events

The table below shows the top 100 pain related interactions that have been reported for low-density lipoprotein particle remodeling. They are ordered first by their pain relevance and then by number of times they were reported in low-density lipoprotein particle remodeling. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT2431 Positive_regulation of Mpo 275 0.70 211.99 78.47
2 INT2429 Negative_regulation of Mpo 128 0.59 93.76 39.57
3 INT116861 Gene_expression of Apoe 182 0.78 100.41 27.26
4 INT5650 Gene_expression of Mpo 117 0.77 80.27 26.42
5 INT58301 Positive_regulation of Mpo 87 0.70 80.19 23.99
6 INT3330 Gene_expression of AGT 149 0.76 98.65 22.73
7 INT3299 Positive_regulation of AGT 126 0.68 79.45 21.91
8 INT6993 Negative_regulation of Mpo 72 0.59 61.83 19.51
9 INT61519 Gene_expression of Mpo 112 0.78 89.29 18.22
10 INT1533 Negative_regulation of AGT 105 0.42 46.54 16.92
11 INT5904 Localization of MPO 62 0.81 36.37 14.64
12 INT3962 Regulation of AGT 50 0.62 20.96 13.01
13 INT4460 Regulation of Mpo 44 0.62 31.16 12.11
14 INT5649 Negative_regulation of Positive_regulation of Mpo 31 0.59 26.62 11.92
15 INT16772 Gene_expression of MPO 81 0.78 90.98 11.9
16 INT398 Localization of AGT 45 0.78 16.97 11.54
17 INT8065 Binding of AGT 54 0.48 20.54 10.85
18 INT12563 Localization of Mpo 33 0.81 20.99 9.58
19 INT45209 Positive_regulation of PLA2G2A 37 0.69 33.21 9.02
20 INT127378 Localization of Mpo 21 0.78 26.36 8.28
21 INT56223 Positive_regulation of MPO 35 0.70 43 8.2
22 INT7125 Gene_expression of PLA2G2A 47 0.78 42.12 7.83
23 INT83006 Gene_expression of AGTR1 59 0.75 54.46 7.27
24 INT197493 Localization of Apoe 61 0.79 27.48 7.06
25 INT16722 Negative_regulation of MPO 25 0.59 18.55 6.99
26 INT142264 Positive_regulation of Apoe 47 0.50 26.35 6.94
27 INT19146 Negative_regulation of Apoa2 19 0.36 5.34 6.73
28 INT182351 Positive_regulation of Gene_expression of Apoe 38 0.50 19.78 6.72
29 INT2925 Positive_regulation of Positive_regulation of Mpo 21 0.70 16.76 6.36
30 INT16359 Positive_regulation of Gene_expression of AGT 30 0.49 28.27 6.14
31 INT63042 Binding of Apoe 59 0.48 31.23 5.88
32 INT7126 Negative_regulation of PLA2G2A 26 0.58 12.97 5.64
33 INT5903 Negative_regulation of Localization of MPO 10 0.59 5.71 5.45
34 INT102891 Positive_regulation of AGTR1 31 0.67 30.57 5.29
35 INT107386 Negative_regulation of AGTR1 37 0.55 35.94 5.15
36 INT7130 Localization of PLA2G2A 32 0.80 20.4 5.05
37 INT55758 Positive_regulation of Apoe 15 0.70 11.71 4.69
38 INT3332 Protein_catabolism of AGT 23 0.87 3.17 4.39
39 INT25634 Binding of Mpo 21 0.48 14.78 4.39
40 INT2453 Positive_regulation of Apoa2 20 0.54 3.49 4.08
41 INT28673 Gene_expression of APOB 51 0.73 34.02 3.95
42 INT111514 Positive_regulation of Gene_expression of Mpo 20 0.49 15.13 3.88
43 INT15033 Gene_expression of Apoe 18 0.78 14.97 3.75
44 INT104624 Negative_regulation of Apoe 26 0.59 19.25 3.71
45 INT52047 Gene_expression of APOE 50 0.78 34.75 3.52
46 INT14994 Positive_regulation of Localization of MPO 12 0.70 6.85 3.37
47 INT117476 Negative_regulation of Gene_expression of Mpo 10 0.43 8.25 3.33
48 INT24983 Binding of MPO 18 0.42 17.56 3.29
49 INT72141 Binding of Apoe 11 0.37 10.91 3.27
50 INT124606 Positive_regulation of Gene_expression of Mpo 14 0.49 12.66 3.24
51 INT97710 Localization of Apoe 1 0.79 7.18 3.2
52 INT207444 Gene_expression of PLA2G7 8 0.71 11.31 3.18
53 INT84320 Negative_regulation of Positive_regulation of Mpo 11 0.46 8 3.09
54 INT58302 Regulation of Mpo 13 0.62 11.14 3.04
55 INT111516 Transcription of Mpo 7 0.68 7.97 2.82
56 INT10556 Regulation of Apoa2 5 0.44 0.51 2.8
57 INT49759 Negative_regulation of CETP 43 0.58 52 2.68
58 INT50080 Binding of APOE 38 0.45 29.61 2.67
59 INT7127 Positive_regulation of Gene_expression of PLA2G2A 16 0.69 17.11 2.63
60 INT97713 Negative_regulation of Apoe 4 0.59 4.57 2.52
61 INT17857 Negative_regulation of Gene_expression of AGT 25 0.46 21.16 2.45
62 INT2452 Localization of Apoa2 9 0.55 0 2.3
63 INT208344 Positive_regulation of Localization of Apoe 22 0.48 9.6 2.27
64 INT27988 Negative_regulation of Positive_regulation of AGT 11 0.42 5.71 2.27
65 INT142265 Regulation of Apoe 20 0.60 9.52 2.23
66 INT108263 Negative_regulation of Gene_expression of Mpo 12 0.52 12.89 2.22
67 INT228707 Positive_regulation of Gene_expression of MPO 10 0.57 17.85 2.1
68 INT84060 Regulation of Apoe 4 0.62 3.33 2.05
69 INT198095 Transcription of PLA2G2A 12 0.68 8.25 2.04
70 INT78773 Regulation of PLA2G2A 11 0.61 9.76 1.91
71 INT40877 Positive_regulation of APOB 35 0.68 32.47 1.86
72 INT56221 Regulation of MPO 8 0.61 8.44 1.84
73 INT21813 Gene_expression of Apoa2 10 0.61 3.68 1.81
74 INT182505 Positive_regulation of Gene_expression of AGTR1 12 0.65 13.18 1.77
75 INT57207 Protein_catabolism of Mpo 9 1.00 3.89 1.7
76 INT127381 Regulation of Localization of Mpo 3 0.54 1.81 1.63
77 INT96814 Negative_regulation of APOE 13 0.59 10.64 1.61
78 INT9466 Binding of APOB 27 0.41 19.36 1.56
79 INT204563 Binding of Mpo 16 0.37 12.1 1.56
80 INT182514 Binding of AGTR1 18 0.47 13.35 1.48
81 INT34768 Negative_regulation of Negative_regulation of AGT 10 0.25 2.79 1.42
82 INT217388 Negative_regulation of Gene_expression of Apoe 11 0.59 6.07 1.4
83 INT182511 Regulation of AGTR1 7 0.44 8.25 1.4
84 INT8067 Negative_regulation of Binding of AGT 12 0.25 10.33 1.39
85 INT113960 Positive_regulation of Gene_expression of APOB 8 0.49 5.88 1.39
86 INT37799 Gene_expression of Apob 13 0.56 10.59 1.36
87 INT97716 Transcription of Apoe 3 0.53 2.61 1.36
88 INT207451 Binding of PLA2G7 3 0.48 11.12 1.32
89 INT11241 Transcription of AGT 4 0.52 1.83 1.27
90 INT20238 Regulation of APOB 9 0.61 11.52 1.26
91 INT124604 Positive_regulation of Negative_regulation of Mpo 3 0.47 1.67 1.24
92 INT97715 Regulation of Gene_expression of Apoe 3 0.62 1.98 1.23
93 INT113336 Positive_regulation of Gene_expression of Apoe 3 0.70 1.79 1.23
94 INT162970 Regulation of Gene_expression of Mpo 8 0.41 9.1 1.21
95 INT47644 Positive_regulation of Localization of AGT 4 0.45 1.24 1.2
96 INT115621 Positive_regulation of Binding of AGT 1 0.02 0 1.15
97 INT207454 Regulation of PLA2G7 5 0.49 3.55 1.12
98 INT207448 Negative_regulation of PLA2G7 5 0.47 5.65 1.08
99 INT111517 Positive_regulation of Transcription of Mpo 4 0.50 4.5 1.05
100 INT217390 Negative_regulation of Positive_regulation of Apoe 3 0.37 1.95 1.05
101 INT198098 Positive_regulation of Transcription of PLA2G2A 4 0.46 4.12 1.02
102 INT207445 Positive_regulation of PLA2G7 7 0.63 7.66 1
103 INT52113 Gene_expression of CETP 25 0.69 25.71 0.99
104 INT228706 Negative_regulation of Gene_expression of MPO 4 0.43 5.95 0.98
105 INT182512 Positive_regulation of Positive_regulation of AGTR1 5 0.47 4.88 0.97
106 INT121823 Negative_regulation of Negative_regulation of Mpo 4 0.39 2.37 0.97
107 INT97714 Negative_regulation of Localization of Apoe 1 0.58 1.83 0.97
108 INT228705 Regulation of Gene_expression of MPO 2 0.45 5.59 0.94
109 INT10827 Gene_expression of Apob 16 0.78 13.08 0.9
110 INT180451 Positive_regulation of Apoa2 15 0.67 12.65 0.89
111 INT9467 Negative_regulation of APOB 14 0.57 10.49 0.88
112 INT127380 Protein_catabolism of Mpo 5 0.86 2.82 0.88
113 INT11949 Negative_regulation of Apob 11 0.09 8.13 0.85
114 INT207450 Regulation of Gene_expression of PLA2G7 1 0.49 2.18 0.85
115 INT10828 Regulation of Apob 7 0.39 7.55 0.83
116 INT70696 Positive_regulation of Localization of Mpo 2 0.44 2.17 0.82
117 INT142597 Regulation of Binding of Apoe 1 0.34 2.21 0.8
118 INT127382 Negative_regulation of Protein_catabolism of Mpo 1 0.41 0.69 0.8
119 INT51739 Negative_regulation of Apob 9 0.42 4.21 0.78
120 INT21943 Positive_regulation of Positive_regulation of AGT 6 0.46 3.29 0.75
121 INT34715 Regulation of Regulation of AGT 2 0.37 0.96 0.75
122 INT102894 Localization of AGTR1 5 0.73 1.75 0.74
123 INT197495 Negative_regulation of Localization of Apoe 6 0.43 2.19 0.73
124 INT44612 Positive_regulation of APOE 16 0.67 5.73 0.72
125 INT270428 Negative_regulation of Binding of APOE 2 0.41 1.16 0.7
126 INT113335 Regulation of Transcription of Apoe 1 0.27 0.51 0.7
127 INT14000 Positive_regulation of Negative_regulation of Mpo 3 0.40 2.07 0.69
128 INT117268 Binding of PLA2G2A 4 0.42 1.99 0.68
129 INT34769 Regulation of Gene_expression of AGT 3 0.19 1.39 0.67
130 INT25374 Negative_regulation of Negative_regulation of Apoa2 1 0.30 0.24 0.67
131 INT354978 Negative_regulation of Localization of Mpo 1 0.52 1.32 0.66
132 INT175580 Localization of APOE 10 0.76 18.84 0.65
133 INT138011 Positive_regulation of Positive_regulation of Mpo 3 0.42 3.84 0.65
134 INT97708 Regulation of Localization of Apoe 1 0.61 2.06 0.62
135 INT50512 Negative_regulation of Binding of Mpo 2 0.43 2.11 0.61
136 INT45724 Positive_regulation of Lipc 2 0.08 0.84 0.58
137 INT267971 Regulation of Localization of AGTR1 1 0.16 1.46 0.57
138 INT113334 Positive_regulation of Positive_regulation of Apoe 1 0.50 0.6 0.56
139 INT283301 Positive_regulation of Localization of Mpo 2 0.44 2.38 0.54
140 INT10983 Binding of Apoa2 7 0.45 4.21 0.52
141 INT197322 Protein_catabolism of Apoe 6 0.71 3.52 0.51
142 INT198092 Positive_regulation of Localization of PLA2G2A 2 0.50 0.98 0.51
143 INT239289 Gene_expression of Abcg1 3 0.31 2.27 0.5
144 INT2430 Negative_regulation of Negative_regulation of Mpo 2 0.37 2.44 0.5
145 INT217370 Phosphorylation of Apoe 2 0.63 1.8 0.49
146 INT47645 Negative_regulation of Localization of AGT 2 0.11 1.09 0.49
147 INT37800 Positive_regulation of Apob 7 0.18 11.01 0.48
148 INT43397 Positive_regulation of Localization of Apoa2 1 0.09 0 0.48
149 INT129857 Regulation of Gene_expression of Mpo 4 0.42 4.36 0.47
150 INT96816 Regulation of APOE 8 0.45 6.62 0.44
151 INT177469 Transcription of MPO 3 0.69 3.08 0.44
152 INT178806 Transcription of Mpo 6 0.64 4.73 0.42
153 INT33017 Negative_regulation of Protein_catabolism of AGT 3 0.37 0 0.42
154 INT107385 Regulation of Negative_regulation of AGTR1 2 0.15 1.26 0.42
155 INT165630 Positive_regulation of Regulation of Mpo 2 0.39 1.49 0.42
156 INT174753 Gene_expression of Apoa2 15 0.75 13.82 0.41
157 INT182507 Negative_regulation of Gene_expression of AGTR1 1 0.40 1.13 0.4
158 INT97712 Negative_regulation of Transcription of Apoe 1 0.43 1.05 0.4
159 INT330125 Transcription of AGTR1 1 0.52 1.29 0.39
160 INT198099 Negative_regulation of Positive_regulation of PLA2G2A 2 0.42 2.58 0.38
161 INT344684 Positive_regulation of Gene_expression of Abcg1 1 0.10 0.95 0.38
162 INT116725 Positive_regulation of CETP 19 0.49 16.33 0.36
163 INT198094 Regulation of Gene_expression of PLA2G2A 3 0.45 2.19 0.35
164 INT95605 Regulation of Binding of AGT 3 0.44 0.2 0.34
165 INT339386 Negative_regulation of Gene_expression of Apob 3 0.43 1.91 0.34
166 INT102889 Positive_regulation of Localization of AGTR1 3 0.38 0.43 0.34
167 INT27928 Phosphorylation of AGT 1 0.52 0.15 0.34
168 INT27929 Negative_regulation of Phosphorylation of AGT 1 0.27 0.15 0.34
169 INT131542 Negative_regulation of Gene_expression of APOE 6 0.40 3.92 0.33
170 INT79251 Regulation of Positive_regulation of PLA2G2A 1 0.27 0.35 0.33
171 INT47453 Positive_regulation of Positive_regulation of Apoa2 3 0.31 1.17 0.32
172 INT229392 Negative_regulation of Positive_regulation of MPO 2 0.20 2.18 0.32
173 INT207447 Negative_regulation of Gene_expression of PLA2G7 3 0.43 1.76 0.31
174 INT83352 Positive_regulation of Negative_regulation of APOB 1 0.01 0.69 0.31
175 INT198097 Regulation of Regulation of PLA2G2A 1 0.27 0.74 0.31
176 INT311128 Positive_regulation of Regulation of Apoe 1 0.30 0.3 0.3
177 INT43396 Regulation of Localization of Apoa2 1 0.09 0 0.3
178 INT175687 Transcription of Apoe 4 0.72 2.12 0.29
179 INT96815 Regulation of Gene_expression of APOE 2 0.62 1.1 0.29
180 INT88770 Negative_regulation of LIPC 1 0.37 0.17 0.28
181 INT297322 Binding of Apoa2 3 0.36 1.7 0.27
182 INT57206 Negative_regulation of Protein_catabolism of Mpo 1 0.43 0.37 0.27
183 INT97711 Positive_regulation of Transcription of Apoe 1 0.46 1.06 0.27
184 INT3331 Positive_regulation of Protein_catabolism of AGT 1 0.33 0 0.27
185 INT254756 Regulation of Positive_regulation of Apoe 1 0.20 0.22 0.26
186 INT263255 Negative_regulation of Negative_regulation of AGTR1 2 0.30 2.88 0.25
187 INT67227 Positive_regulation of Binding of Apoa2 2 0.26 1.31 0.25
188 INT207452 Localization of PLA2G7 1 0.68 0.74 0.25
189 INT347412 Negative_regulation of Localization of Mpo 1 0.05 0.59 0.24
190 INT2450 Negative_regulation of Positive_regulation of Apoa2 1 0.21 0 0.24
191 INT116724 Positive_regulation of Gene_expression of CETP 3 0.41 7.92 0.23
192 INT198096 Positive_regulation of Positive_regulation of PLA2G2A 1 0.50 0.84 0.23
193 INT194472 Positive_regulation of Gene_expression of Apob 2 0.15 1.71 0.22
194 INT2449 Negative_regulation of Localization of Apoa2 1 0.19 0 0.22
195 INT281349 Positive_regulation of Binding of Mpo 1 0.50 1.62 0.22
196 INT323964 Negative_regulation of Binding of Apoe 1 0.39 0.35 0.22
197 INT323965 Protein_catabolism of Apoa2 1 0.01 0.34 0.22
198 INT70647 Regulation of CETP 7 0.61 4.53 0.21
199 INT198892 Regulation of Binding of Apoe 6 0.45 2.94 0.21
200 INT180454 Negative_regulation of Apoa2 6 0.42 7.42 0.2
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