GO:0034394

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Name protein localization at cell surface
Categary Process
Go Slim No
Go Link GO:0034394
Unique Molecular Interactions 111
Total Molecular Interactions 170
Total Single Events 1300
Pain Genes Associated 18

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for protein localization at cell surface. They are ordered first by their pain relevance and then by number of times they were reported for protein localization at cell surface. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT259233 Binding of Oprm1 and Flna 1 0.03 0.25 25.89
2 INT221180 Binding of OPRM1 and Flna 1 0.09 0.22 12.65
3 INT259209 Binding of Glul and Flna 1 0.03 0 4.2
4 INT259230 Negative_regulation of Binding of Oprm1 and Flna 1 0.02 0 4.15
5 INT152035 Binding of HLA-A and MRAP 2 0.31 6.95 3.4
6 INT221181 Binding of GOPC and Flna 1 0.03 0.06 2.08
7 INT221182 Negative_regulation of Binding of OPRM1 and Flna 1 0.07 0 1.57
8 INT259232 Binding of Flna and Positive_regulation of Localization of Oprm1 1 0.03 0 1.39
9 INT259211 Binding of Ppp1r9b and Flna 1 0.06 0 1.33
10 INT259229 Positive_regulation of Binding of Oprm1 and Flna 1 0.02 0 1.23
11 INT113946 Binding of FLNA and OPRM1 1 0.10 0.37 0.9
12 INT162164 ARF6 Regulation of Positive_regulation of PLD2 1 0.60 0 0.74
13 INT162162 ARF6 Regulation of OPRM1 1 0.19 0 0.71
14 INT28711 Binding of HLA-B and MRAP 2 0.23 0.96 0.69
15 INT202018 Binding of KIR3DS1 and MRAP 1 0.13 0.59 0.59
16 INT77380 Tmie Negative_regulation of Fbln5 1 0.01 0 0.59
17 INT333991 Binding of FLNA and SELL 1 0.00 1.69 0.55
18 INT222691 Negative_regulation of Binding of FLNA and TNF 1 0.14 1.92 0.54
19 INT222692 Binding of FLNA and TNF 1 0.12 1.92 0.53
20 INT254348 Binding of ANGPT1 and TEK 1 0.04 1.72 0.48
21 INT77377 Binding of Cnr1 and Fbln5 1 0.02 0 0.48
22 INT202019 Binding of KIR3DL1 and MRAP 1 0.21 0.77 0.46
23 INT340438 Binding of HLA-DMA and MRAP 1 0.02 1.69 0.43
24 INT300609 Binding of Ctnnb1 and Wnt2 1 0.02 0.25 0.37
25 INT171874 Binding of SQLE and MRAP 1 0.00 1.29 0.35
26 INT124378 Prodh2 Positive_regulation of Ctnnb1 1 0.00 0.59 0.35
27 INT224700 TNF Positive_regulation of Angpt1 1 0.00 0.63 0.34
28 INT181899 TNF Regulation of ANGPT1 1 0.03 1.22 0.33
29 INT113950 FLNA Regulation of Oprd1 1 0.00 0.16 0.32
30 INT250957 Binding of MRAP and SFTPA1 1 0.02 0.45 0.29
31 INT191619 Binding of App and Flna 1 0.04 0.18 0.24
32 INT202016 Binding of LILRB2 and MRAP 1 0.14 0.38 0.23
33 INT202021 Negative_regulation of Binding of KIR3DL1 and MRAP 1 0.19 0.38 0.23
34 INT202017 Negative_regulation of Binding of LILRB2 and MRAP 1 0.13 0.38 0.23
35 INT202014 Binding of LILRA2 and MRAP 1 0.15 0.38 0.23
36 INT303029 Binding of TEK and Angpt1 1 0.26 1.82 0.22
37 INT191609 Binding of Drd3 and Flna 1 0.06 0.42 0.17
38 INT191615 Binding of Nf1 and Flna 1 0.08 0.53 0.17
39 INT46426 Binding of LRRC23 and MRAP 1 0.07 0.09 0.14
40 INT251115 Positive_regulation of Binding of AR and Ctnnb1 1 0.01 1.02 0.13
41 INT251114 Binding of AR and Ctnnb1 1 0.01 1 0.12
42 INT199595 FGF7 Positive_regulation of Transcription of TNF 1 0.40 0.58 0.11
43 INT192249 Angpt1 Positive_regulation of Localization of NOS3 1 0.01 0.46 0.09
44 INT192248 Angpt1 Positive_regulation of NOS3 1 0.01 0.46 0.09
45 INT192250 Positive_regulation of Angpt1 Positive_regulation of NOS3 1 0.01 0.46 0.09
46 INT199594 FGF7 Positive_regulation of NFE2L2 1 0.01 0.52 0.09
47 INT141317 Binding of Fbln5 and Olfr74 1 0.00 0.31 0.09
48 INT141257 Binding of S100A8 and VCL 1 0.36 0.97 0.09
49 INT199604 Binding of FGF7 and Fgf1 1 0.03 0.21 0.08
50 INT199603 Positive_regulation of Binding of FGF7 and Fgf1 1 0.04 0.21 0.08
51 INT46424 Binding of NCAM1 and MRAP 1 0.00 0.08 0.08
52 INT303561 Binding of Fgf7 and Fgfr2 1 0.42 0.88 0.07
53 INT236531 Binding of Cacna1f and Flna 1 0.08 0 0.07
54 INT65157 Binding of MRAP and Drb1 1 0.01 0.16 0.07
55 INT303562 Binding of Fgf10 and Fgfr2 1 0.40 0.88 0.07
56 INT290905 Gene_expression of Shh Positive_regulation of Gene_expression of Angpt1 1 0.14 0 0.06
57 INT141256 S100A8 Positive_regulation of VCL 1 0.50 0.99 0.06
58 INT75235 Binding of MRAP and BW6 1 0.07 0.06 0.06
59 INT141258 S100A8 Negative_regulation of VCL 1 0.43 0.99 0.06
60 INT250015 Binding of FLNA and Nos3 1 0.05 1.09 0.06
61 INT202930 Binding of LAMB1 and Fbln5 1 0.01 0.45 0.05
62 INT214015 Negative_regulation of Binding of Dnahc8 and Ank2 1 0.04 1.09 0.04
63 INT214013 Binding of Dnahc8 and Ank2 1 0.03 1.08 0.04
64 INT305383 Binding of NKX2-5 and FLNA 1 0.10 0.7 0.04
65 INT178501 Angpt1 Positive_regulation of Tek 1 0.06 0.78 0.04
66 INT298703 Angpt1 Regulation of Tek 1 0.12 0.27 0.03
67 INT303563 Binding of Fgf10 and Dysf 1 0.00 0.44 0.03
68 INT303559 Binding of Fgf7 and Dysf 1 0.01 0.44 0.03
69 INT213585 Binding of CFTR and FLNA 1 0.14 0.11 0.03
70 INT291199 Binding of VEGFA and Angpt1 1 0.08 0.69 0
71 INT355603 Binding of CTNNA1 and Ctnnb1 1 0.00 1.07 0
72 INT220818 Binding of Ctnnb1 and Myc 1 0.06 0.13 0
73 INT214472 Binding of LPL and GPIHBP1 1 0.29 1.17 0
74 INT306114 GOPC Regulation of Gene_expression of FGF7 1 0.05 0.45 0
75 INT338018 Binding of AR and Flna 1 0.11 0.33 0
76 INT292088 Binding of AMELX and ANGPT1 1 0.00 0.9 0
77 INT255164 Regulation of PM20D2 Regulation of FLNA 1 0.00 0.82 0
78 INT286566 Binding of Ctnnb1 and Cdh6 1 0.00 1 0
79 INT286562 Gene_expression of Pkd1 Positive_regulation of Ctnnb1 1 0.02 0.52 0
80 INT136693 Gtf3a Positive_regulation of Ctnnb1 1 0.05 0 0
81 INT294066 ANGPT1 Positive_regulation of VEGFA 1 0.01 0.1 0
82 INT236528 Binding of Cav1 and Flna 1 0.06 0.09 0
83 INT109817 Ace2 Positive_regulation of Angpt1 1 0.05 0.31 0
84 INT228002 Binding of Loxl1 and Fbln5 1 0.34 1.57 0
85 INT319042 Negative_regulation of Binding of Fgf7 and Fig4 1 0.07 0.2 0
86 INT255165 PM20D2 Regulation of FLNA 1 0.00 0.76 0
87 INT220821 Binding of MAX and Ctnnb1 1 0.09 0.13 0
88 INT268887 Binding of ANGPT1 and Tek 1 0.10 0 0
89 INT176096 Regulation of Binding of Angpt1 and Tek 1 0.07 0.54 0
90 INT176097 Binding of Angpt1 and Tek 1 0.06 0.48 0
91 INT286561 Binding of Ctnnb1 and Cdh2 1 0.00 1.06 0
92 INT338021 Binding of Flna and Regulation of Transcription of AR 1 0.14 0.33 0
93 INT202675 Fgf10 Positive_regulation of Fgfr2 1 0.45 0.07 0
94 INT250950 Binding of USO1 and MRAP 1 0.02 0.09 0
95 INT286567 Prkd1 Regulation of Ctnnb1 1 0.01 0.39 0
96 INT270460 Shh Positive_regulation of Gene_expression of Angpt1 1 0.04 0.08 0
97 INT319043 Binding of Fgf7 and Fig4 1 0.06 0.26 0
98 INT255163 Binding of FLNA and PM20D2 1 0.00 0 0
99 INT228004 Positive_regulation of Binding of Loxl1 and Fbln5 1 0.35 0.54 0
100 INT236529 Binding of Om and Flna 1 0.00 0.09 0
101 INT286572 Binding of Ctnnb1 and Pkd1 1 0.02 0.96 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for protein localization at cell surface. They are ordered first by their pain relevance and then by number of times they were reported in protein localization at cell surface. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT221172 Binding of Flna 32 0.42 1.37 51.59
2 INT636 Binding of MRAP 54 0.48 40.36 18.77
3 INT1873 Gene_expression of MRAP 51 0.76 31.75 13.92
4 INT221167 Gene_expression of Flna 11 0.60 0.69 11.81
5 INT637 Positive_regulation of MRAP 23 0.67 21.13 9.97
6 INT68373 Negative_regulation of FLNA 59 0.57 60.46 9.55
7 INT221173 Negative_regulation of Binding of Flna 4 0.33 0.13 8.25
8 INT113948 Gene_expression of FLNA 32 0.73 36.06 4.81
9 INT39948 Binding of FLNA 45 0.42 58.05 4.27
10 INT221168 Localization of Flna 1 0.58 0.05 4.05
11 INT63880 Positive_regulation of FLNA 29 0.59 13.88 3.97
12 INT17883 Regulation of MRAP 8 0.44 3.59 3.12
13 INT221171 Positive_regulation of Localization of Flna 1 0.39 0.05 2.9
14 INT101567 Gene_expression of Ctnnb1 7 0.64 10.11 2.89
15 INT83374 Gene_expression of FGF7 83 0.78 44.18 2.6
16 INT99550 Regulation of FLNA 51 0.54 27.88 2.58
17 INT46646 Localization of FLNA 19 0.73 18.83 2.53
18 INT259224 Negative_regulation of Flna 1 0.23 0.15 2.51
19 INT96529 Positive_regulation of Fbln5 1 0.11 1.09 2.35
20 INT221177 Negative_regulation of Gene_expression of Flna 2 0.33 0 2.22
21 INT153718 Gene_expression of ANGPT1 15 0.45 10.82 2.13
22 INT221179 Regulation of Flna 1 0.24 0.13 2.04
23 INT81641 Gene_expression of Ctnnb1 23 0.72 14.93 1.97
24 INT214005 Gene_expression of Ank2 1 0.78 29.4 1.88
25 INT111944 Phosphorylation of VCL 3 0.73 5.23 1.72
26 INT221166 Positive_regulation of Flna 2 0.39 0.09 1.7
27 INT123990 Positive_regulation of Ctnnb1 8 0.43 2.85 1.63
28 INT99391 Localization of Ctnnb1 7 0.80 5.84 1.61
29 INT2016 Negative_regulation of MRAP 6 0.41 3.21 1.59
30 INT123926 Gene_expression of Angpt1 28 0.54 21.74 1.47
31 INT259219 Negative_regulation of Negative_regulation of Flna 1 0.23 0 1.47
32 INT181032 Gene_expression of Fgf7 8 0.61 5.96 1.41
33 INT178494 Gene_expression of Angpt1 10 0.37 9.77 1.28
34 INT199601 Positive_regulation of FGF7 9 0.50 6.13 1.22
35 INT99389 Negative_regulation of Ctnnb1 8 0.45 3.97 1.21
36 INT109078 Positive_regulation of ANGPT1 7 0.22 3.08 1.21
37 INT101570 Positive_regulation of Gene_expression of Ctnnb1 1 0.58 5.7 1.07
38 INT162167 Negative_regulation of Gene_expression of ARF6 1 0.38 0 0.94
39 INT162168 Gene_expression of ARF6 1 0.68 0 0.92
40 INT199598 Binding of FGF7 4 0.48 2.83 0.9
41 INT142423 Negative_regulation of Positive_regulation of FLNA 2 0.05 0.99 0.89
42 INT101566 Negative_regulation of Gene_expression of Ctnnb1 1 0.35 2.28 0.88
43 INT172055 Positive_regulation of Binding of MRAP 1 0.33 1.69 0.84
44 INT109080 Negative_regulation of ANGPT1 8 0.14 3.17 0.82
45 INT111941 Regulation of Phosphorylation of VCL 1 0.27 0.66 0.8
46 INT111942 Positive_regulation of Phosphorylation of VCL 1 0.30 0.67 0.8
47 INT123927 Positive_regulation of Gene_expression of Angpt1 12 0.48 10.18 0.71
48 INT99708 Gene_expression of Fgf7 7 0.76 7.42 0.7
49 INT99390 Regulation of Ctnnb1 4 0.62 3.12 0.64
50 INT718 Localization of MRAP 1 0.68 1.03 0.59
51 INT124042 Localization of FGF7 10 0.80 4.13 0.57
52 INT296583 Gene_expression of Fgf10 3 0.59 2.64 0.57
53 INT296594 Regulation of Fgf10 1 0.15 1.53 0.56
54 INT199602 Positive_regulation of Gene_expression of FGF7 12 0.70 7.47 0.55
55 INT76960 Negative_regulation of Ctnnb1 5 0.57 3.46 0.53
56 INT81645 Positive_regulation of Gene_expression of Ctnnb1 6 0.63 3.78 0.47
57 INT96909 Regulation of Angpt1 2 0.17 0.37 0.43
58 INT76958 Positive_regulation of Ctnnb1 14 0.64 5.48 0.41
59 INT95872 Localization of Ctnnb1 7 0.74 2.75 0.4
60 INT262902 Regulation of Binding of FGF7 1 0.02 0.88 0.4
61 INT178497 Positive_regulation of Gene_expression of Angpt1 4 0.19 3.65 0.39
62 INT228271 Localization of Fgf7 2 0.28 1.59 0.39
63 INT113949 Positive_regulation of Gene_expression of FLNA 2 0.44 0.34 0.39
64 INT128792 Transcription of MRAP 1 0.38 0.39 0.39
65 INT221178 Positive_regulation of Gene_expression of Flna 1 0.39 0 0.38
66 INT214004 Regulation of Gene_expression of Ank2 1 0.45 2.79 0.38
67 INT81644 Regulation of Ctnnb1 5 0.41 3.38 0.37
68 INT214618 Transcription of FLNA 4 0.51 8.06 0.37
69 INT81643 Regulation of Gene_expression of Ctnnb1 3 0.57 1.5 0.37
70 INT228280 Regulation of Gene_expression of Fgf7 1 0.18 0.95 0.34
71 INT257954 Regulation of FGF7 2 0.45 0.52 0.32
72 INT108324 Negative_regulation of Gene_expression of Ctnnb1 1 0.06 1.43 0.31
73 INT132532 Positive_regulation of Gene_expression of MRAP 1 0.49 0.63 0.28
74 INT1115 Regulation of Positive_regulation of MRAP 1 0.45 0.44 0.25
75 INT96908 Protein_catabolism of Angpt1 1 0.41 0.26 0.24
76 INT151719 Negative_regulation of Positive_regulation of Ctnnb1 1 0.23 1.9 0.24
77 INT220396 Negative_regulation of Angpt1 4 0.26 1.64 0.23
78 INT213997 Negative_regulation of Gene_expression of Ank2 1 0.43 5.06 0.22
79 INT181791 Positive_regulation of Gene_expression of ANGPT1 1 0.29 1.27 0.2
80 INT199599 Negative_regulation of Gene_expression of FGF7 3 0.48 0.78 0.19
81 INT213999 Phosphorylation of Ank2 1 0.82 0.21 0.19
82 INT213996 Negative_regulation of Phosphorylation of Ank2 1 0.43 0.21 0.19
83 INT134059 Negative_regulation of Negative_regulation of FLNA 1 0.02 0.38 0.18
84 INT99392 Negative_regulation of Localization of Ctnnb1 2 0.59 1.43 0.17
85 INT151721 Negative_regulation of Localization of Ctnnb1 1 0.23 0.96 0.17
86 INT325506 Positive_regulation of Localization of Ctnnb1 1 0.05 0.28 0.17
87 INT199600 Negative_regulation of Localization of FGF7 1 0.35 1.09 0.16
88 INT156590 Negative_regulation of Negative_regulation of ANGPT1 1 0.10 0.33 0.16
89 INT290923 Positive_regulation of Angpt1 3 0.48 3.62 0.14
90 INT99709 Regulation of Gene_expression of Fgf7 3 0.44 0.19 0.14
91 INT214007 Negative_regulation of Ank2 1 0.43 2.63 0.14
92 INT285494 Positive_regulation of Gene_expression of Fgf7 2 0.40 1.48 0.13
93 INT119194 Negative_regulation of FGF7 2 0.43 1.42 0.13
94 INT130374 Transcription of Ctnnb1 1 0.19 0 0.13
95 INT214000 Binding of Ank2 1 0.48 1.12 0.12
96 INT304610 Positive_regulation of Localization of FLNA 1 0.09 0.98 0.12
97 INT354414 Localization of ANGPT1 1 0.10 0 0.1
98 INT56836 Regulation of Binding of MRAP 1 0.02 0.2 0.1
99 INT285509 Negative_regulation of Gene_expression of Fgf7 1 0.14 1.14 0.1
100 INT291188 Regulation of Gene_expression of Angpt1 1 0.31 1.78 0.08
101 INT291183 Negative_regulation of Angpt1 1 0.30 0.89 0.08
102 INT305385 Negative_regulation of Localization of FLNA 1 0.16 0.79 0.08
103 INT99713 Positive_regulation of Gene_expression of Fgf7 3 0.45 0.92 0.07
104 INT141261 Negative_regulation of VCL 1 0.45 0.95 0.07
105 INT291195 Negative_regulation of Gene_expression of Angpt1 1 0.41 2.29 0.07
106 INT3374 Positive_regulation of Positive_regulation of MRAP 1 0.49 0.7 0.07
107 INT200103 Regulation of Gene_expression of FGF7 3 0.62 3.41 0.06
108 INT290930 Localization of Angpt1 1 0.21 0 0.06
109 INT159002 Gene_expression of Fbln5 2 0.55 0.47 0.05
110 INT202925 Localization of Fbln5 1 0.43 0.48 0.05
111 INT263798 Gene_expression of VCL 1 0.18 1.14 0.05
112 INT178418 Binding of Fgf7 1 0.16 1.26 0.05
113 INT178278 Regulation of Positive_regulation of FLNA 1 0.04 0.4 0.05
114 INT290916 Regulation of Angpt1 2 0.31 1.01 0.04
115 INT258065 Protein_catabolism of ANGPT1 1 0.01 0.47 0.04
116 INT291193 Binding of Angpt1 1 0.26 1.87 0.04
117 INT11697 Positive_regulation of Negative_regulation of MRAP 1 0.49 0.08 0.04
118 INT236523 Binding of Flna 3 0.30 0.45 0.03
119 INT260760 Positive_regulation of Fgf10 2 0.53 0.43 0.03
120 INT178396 Positive_regulation of Fgf7 2 0.55 0.98 0.03
121 INT303535 Positive_regulation of Gene_expression of Fgf10 1 0.53 0.34 0.03
122 INT294078 Regulation of ANGPT1 3 0.04 1.25 0
123 INT276544 Gene_expression of Flna 3 0.63 1.97 0
124 INT268882 Binding of ANGPT1 3 0.07 0.89 0
125 INT99714 Transcription of Fgf7 2 0.67 0.22 0
126 INT76959 Binding of Ctnnb1 2 0.34 0.69 0
127 INT276523 Negative_regulation of Gene_expression of Flna 2 0.48 0.8 0
128 INT294081 Negative_regulation of Gene_expression of ANGPT1 2 0.04 0.19 0
129 INT319037 Positive_regulation of Regulation of Fgf7 1 0.49 0.08 0
130 INT230651 Phosphorylation of Ctnnb1 1 0.10 0 0
131 INT230674 Positive_regulation of Phosphorylation of Ctnnb1 1 0.06 0 0
132 INT319041 Regulation of Fgf7 1 0.44 0.08 0
133 INT326137 Protein_catabolism of Ctnnb1 1 0.02 1.08 0
134 INT306120 Regulation of Transcription of FGF7 1 0.62 1.47 0
135 INT355576 Negative_regulation of Negative_regulation of Ctnnb1 1 0.02 1.14 0
136 INT319039 Negative_regulation of Fgf7 1 0.42 0.18 0
137 INT214001 Protein_catabolism of Ank2 1 0.66 0.08 0
138 INT220769 Positive_regulation of Positive_regulation of Ctnnb1 1 0.10 0 0
139 INT214003 Regulation of Ank2 1 0.45 0 0
140 INT255171 Negative_regulation of Binding of FLNA 1 0.14 0.39 0
141 INT306124 Transcription of FGF7 1 0.72 3.68 0
142 INT130598 Negative_regulation of Gene_expression of MRAP 1 0.35 0.19 0
143 INT214620 Regulation of Localization of FLNA 1 0.02 0.46 0
144 INT213995 Positive_regulation of Ank2 1 0.50 2.86 0
145 INT214009 Positive_regulation of Gene_expression of Ank2 1 0.70 2.86 0
146 INT214477 Negative_regulation of GPIHBP1 1 0.43 0.56 0
147 INT306126 Negative_regulation of Transcription of FGF7 1 0.43 0.56 0
148 INT159004 Positive_regulation of Gene_expression of Fbln5 1 0.41 0 0
149 INT319038 Negative_regulation of Gene_expression of Fgf7 1 0.42 0.18 0
150 INT283878 Localization of VCL 1 0.19 1.12 0
151 INT214621 Regulation of Gene_expression of FLNA 1 0.02 1.09 0
152 INT319040 Protein_catabolism of Fgf7 1 0.64 0.17 0
153 INT159003 Regulation of Fbln5 1 0.37 0 0
154 INT306121 Positive_regulation of Localization of FGF7 1 0.50 0.12 0
155 INT239107 Binding of Fgf7 1 0.16 0.35 0
156 INT337958 Localization of Flna 1 0.61 0.43 0
157 INT307737 Binding of VCL 1 0.13 0.36 0
158 INT122566 Binding of Fbln5 1 0.03 0.1 0
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