GO:0034435

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Name cholesterol esterification
Categary Process
Go Slim No
Go Link GO:0034435
Unique Molecular Interactions 66
Total Molecular Interactions 69
Total Single Events 405
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cholesterol esterification. They are ordered first by their pain relevance and then by number of times they were reported for cholesterol esterification. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT48455 Scd1 Regulation of Penk 1 0.06 0 0.88
2 INT70670 Scd1 Positive_regulation of Gene_expression of Penk 1 0.11 0.1 0.86
3 INT231534 Binding of JAK1 and SOAT1 1 0.01 0.6 0.64
4 INT278688 MTX1 Negative_regulation of Positive_regulation of SOAT1 1 0.04 0.69 0.54
5 INT220741 Binding of EGFR and SOAT1 1 0.02 0.37 0.49
6 INT307781 Apoa1 Positive_regulation of LCAT 1 0.76 1.19 0.45
7 INT43365 Scd1 Negative_regulation of Gnrh1 1 0.13 0.1 0.44
8 INT307780 Apoa1 Positive_regulation of Soat1 1 0.04 1.14 0.42
9 INT43366 Scd1 Regulation of Gene_expression of Gnrh1 1 0.08 0.07 0.39
10 INT234608 Socs3 Negative_regulation of SOAT1 1 0.01 0.54 0.39
11 INT43367 Scd1 Regulation of Gnrh1 1 0.08 0.07 0.39
12 INT43363 Scd1 Regulation of Barhl1 1 0.03 0.07 0.39
13 INT237369 SOAT1 Negative_regulation of Phosphorylation of JAK1 1 0.00 0 0.38
14 INT231535 Binding of JAK2 and SOAT1 1 0.01 0.3 0.35
15 INT122049 Binding of HSD11B1 and Lcat 1 0.21 0.83 0.31
16 INT303949 LEPR Positive_regulation of SOAT1 1 0.01 0.22 0.28
17 INT16811 Binding of Scd1 and Oprl1 1 0.00 0 0.24
18 INT303606 Binding of IL18 and SOAT1 1 0.05 0.52 0.22
19 INT308518 HSP90B1 Positive_regulation of Positive_regulation of SOAT1 1 0.00 0.65 0.18
20 INT47344 CPZ Negative_regulation of LCAT 1 0.29 0 0.18
21 INT26086 Binding of Scd1 and St8sia2 1 0.00 0.06 0.16
22 INT186380 Binding of SOAT1 and Stat6 1 0.02 0.11 0.15
23 INT332256 Pdgfa Positive_regulation of SOAT1 1 0.01 0.51 0.14
24 INT323877 LEP Positive_regulation of SOAT1 1 0.20 1.26 0.14
25 INT262618 Binding of SOAT1 and Kras 1 0.00 0.81 0.12
26 INT323879 LEP Regulation of SOAT1 1 0.15 1.15 0.1
27 INT194742 SOAT1 Positive_regulation of Positive_regulation of IK 1 0.00 0.1 0.09
28 INT36128 Binding of Scd1 and Mme 1 0.00 0 0.09
29 INT355021 Cntf Positive_regulation of SOAT1 1 0.02 0.7 0.08
30 INT355020 Lif Positive_regulation of SOAT1 1 0.02 0.7 0.08
31 INT239346 Olfr642 Positive_regulation of Lcat 1 0.00 1.06 0.07
32 INT239327 Positive_regulation of Binding of Lcat and Hdl1 1 0.06 1.52 0.06
33 INT239331 RCT Positive_regulation of Lcat 1 0.08 1.08 0.06
34 INT239354 CETP Positive_regulation of Lcat 1 0.28 1.09 0.06
35 INT239326 Binding of Lcat and Hdl1 1 0.05 1.52 0.06
36 INT212440 STAT3 Regulation of Phosphorylation of SOAT1 1 0.11 1.42 0.05
37 INT301653 Mlxipl Positive_regulation of Gene_expression of Scd1 1 0.08 0.5 0.05
38 INT342359 Arrd1 Positive_regulation of Scd1 1 0.01 0.8 0.04
39 INT326065 APOE Positive_regulation of LCAT 1 0.53 0.84 0
40 INT326061 Binding of HSD11B1 and LCAT 1 0.11 0.89 0
41 INT253588 Csnk2a2 Regulation of Gene_expression of SOAT1 1 0.03 0 0
42 INT239342 Lcat Regulation of Apoa1 1 0.16 0.65 0
43 INT301620 Positive_regulation of Binding of Ros1 and Scd1 1 0.03 0.41 0
44 INT152049 Scd1 Negative_regulation of Trav6-3 1 0.00 0.19 0
45 INT301652 Binding of Ros1 and Scd1 1 0.02 0.41 0
46 INT295499 Lcat Regulation of Transcription of Hmgcr 1 0.04 0.2 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for cholesterol esterification. They are ordered first by their pain relevance and then by number of times they were reported in cholesterol esterification. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT39457 Positive_regulation of SOAT1 32 0.67 22.8 8.28
2 INT186063 Phosphorylation of SOAT1 29 0.28 11.77 5.34
3 INT44873 Negative_regulation of LCAT 16 0.59 6.92 3.13
4 INT231557 Positive_regulation of Phosphorylation of SOAT1 7 0.22 5.22 2.33
5 INT78960 Binding of SOAT1 9 0.36 2.56 1.92
6 INT49377 Negative_regulation of Scd1 11 0.49 9.84 1.88
7 INT39458 Negative_regulation of SOAT1 8 0.57 10.56 1.83
8 INT39459 Gene_expression of SOAT1 10 0.75 7.62 1.52
9 INT100540 Localization of SOAT1 9 0.78 2.67 1.42
10 INT155845 Transcription of SOAT1 6 0.67 2.89 1.4
11 INT60291 Regulation of SOAT1 9 0.19 3.99 1.17
12 INT44874 Regulation of LCAT 1 0.62 0.15 1
13 INT114504 Positive_regulation of Scd1 10 0.48 3.77 0.8
14 INT48454 Localization of Scd1 1 0.39 0 0.62
15 INT302813 Positive_regulation of Positive_regulation of SOAT1 3 0.22 4.2 0.58
16 INT264133 Protein_catabolism of SOAT1 1 0.05 0.38 0.55
17 INT26073 Gene_expression of Scd1 17 0.70 9.17 0.47
18 INT98945 Negative_regulation of Positive_regulation of SOAT1 1 0.41 0.65 0.46
19 INT249596 Positive_regulation of Gene_expression of SOAT1 2 0.09 1.1 0.42
20 INT43361 Binding of Scd1 1 0.10 0.08 0.42
21 INT122047 Positive_regulation of Lcat 3 0.35 1.94 0.4
22 INT43360 Negative_regulation of Scd1 1 0.13 0.09 0.4
23 INT291958 Negative_regulation of Phosphorylation of SOAT1 2 0.05 0.58 0.39
24 INT4439 Positive_regulation of Scd1 1 0.34 0.19 0.39
25 INT317741 Positive_regulation of Transcription of SOAT1 2 0.49 0.62 0.35
26 INT16808 Binding of Scd1 5 0.00 7.18 0.33
27 INT124019 Regulation of Scd1 1 0.01 0 0.31
28 INT175691 Gene_expression of Lcat 6 0.57 7.87 0.21
29 INT323896 Regulation of Phosphorylation of SOAT1 2 0.14 1.25 0.21
30 INT170734 Positive_regulation of Gene_expression of Scd1 5 0.48 5.87 0.13
31 INT3442 Negative_regulation of Lcat 2 0.42 4.36 0.12
32 INT239288 Binding of Lcat 1 0.27 2.59 0.12
33 INT239277 Positive_regulation of Binding of Lcat 1 0.37 1.09 0.06
34 INT239298 Regulation of Lcat 1 0.33 1.96 0.06
35 INT187415 Gene_expression of LCAT 3 0.39 1.26 0
36 INT170743 Negative_regulation of Gene_expression of Scd1 2 0.38 1.57 0
37 INT307203 Transcription of Scd1 2 0.32 1.11 0
38 INT253561 Regulation of Gene_expression of SOAT1 1 0.04 0 0
39 INT239274 Negative_regulation of Gene_expression of Lcat 1 0.43 1.6 0
40 INT170740 Localization of Scd1 1 0.17 0.99 0
41 INT273148 Localization of LCAT 1 0.38 0.91 0
42 INT312779 Gene_expression of Lcat 1 0.37 0.82 0
43 INT312790 Regulation of Gene_expression of Lcat 1 0.21 0.88 0
44 INT273152 Positive_regulation of Localization of LCAT 1 0.26 0.91 0
45 INT300106 Negative_regulation of Gene_expression of SOAT1 1 0.06 0.8 0
46 INT312775 Positive_regulation of Lcat 1 0.19 0.91 0
47 INT138623 Negative_regulation of Gene_expression of Scd1 1 0.20 0.57 0
48 INT295508 Transcription of Lcat 1 0.08 0.2 0
49 INT175683 Negative_regulation of Lcat 1 0.21 2.28 0
50 INT307184 Positive_regulation of Transcription of Scd1 1 0.28 0 0
51 INT312791 Regulation of Lcat 1 0.13 0.83 0
52 INT295103 Positive_regulation of Binding of Scd1 1 0.29 0.05 0
53 INT138630 Gene_expression of Scd1 1 0.37 0.56 0
54 INT249595 Positive_regulation of Binding of SOAT1 1 0.03 0.3 0
55 INT300233 Positive_regulation of Gene_expression of LCAT 1 0.29 0.98 0
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