GO:0034704

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Name calcium channel complex
Categary Component
Go Slim No
Go Link GO:0034704
Unique Molecular Interactions 31
Total Molecular Interactions 33
Total Single Events 279
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for calcium channel complex. They are ordered first by their pain relevance and then by number of times they were reported for calcium channel complex. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT209312 Trpc5 Positive_regulation of Gene_expression of Scx 1 0.15 0.05 0.33
2 INT261629 Binding of CPD and TRPC5 1 0.04 0.52 0.32
3 INT309057 Binding of Trpc1 and Trpc5 1 0.27 0.21 0.32
4 INT309054 Binding of Trpc3 and Trpc5 1 0.18 0.23 0.29
5 INT309059 Binding of Trpc6 and Trpc5 1 0.24 0.23 0.29
6 INT309063 Binding of Trpc3 and Trpc4 1 0.11 0.23 0.28
7 INT309056 Binding of Trpc4 and Trpc6 1 0.15 0.23 0.28
8 INT107885 Negative_regulation of TRPC6 Negative_regulation of Trpc4 1 0.01 0 0.08
9 INT8928 Negative_regulation of Trpc4 Negative_regulation of Positive_regulation of Acta1 1 0.02 0.18 0.05
10 INT252801 PPP2R4 Regulation of Positive_regulation of CREB1 1 0.01 2.71 0.04
11 INT252780 Positive_regulation of CREB1 Positive_regulation of PPP2R4 1 0.01 2.71 0.04
12 INT252818 PPP2R4 Regulation of Positive_regulation of DDIT3 1 0.04 3.07 0.04
13 INT329946 Binding of Stmn2 and Trpc5 1 0.03 0.15 0
14 INT192046 Negative_regulation of Binding of RYR2 and Cbx5 1 0.01 1.12 0
15 INT329996 Binding of SGCD and AKAP6 1 0.37 0.46 0
16 INT249178 Negative_regulation of CA2 Positive_regulation of TRPC4 1 0.16 0 0
17 INT309060 Trpc5 Positive_regulation of Ca2 1 0.11 0.06 0
18 INT273289 Binding of Psen2 and Ryr2 1 0.27 4.53 0
19 INT192049 Negative_regulation of Binding of RYR2 and Cbx1 1 0.01 1.12 0
20 INT276585 Binding of Trpc5 and Trpc6 1 0.17 0.26 0
21 INT192045 Jup Positive_regulation of RYR2 1 0.11 0.29 0
22 INT329995 Binding of KCNMA1 and AKAP6 1 0.40 0.48 0
23 INT293357 RORC Regulation of PPP2R4 1 0.00 0 0
24 INT249157 Negative_regulation of CA2 Positive_regulation of TRPC5 1 0.14 0 0
25 INT329945 Binding of Trpc5 and Negr1 1 0.00 0.15 0
26 INT192047 Binding of RYR2 and Cbx1 1 0.01 1.12 0
27 INT192043 Binding of RYR2 and Cbx5 1 0.01 1.12 0
28 INT329992 Binding of SNRNP70 and AKAP6 1 0.03 0.95 0
29 INT192048 Binding of DSP and Ryr2 1 0.24 1.1 0
30 INT309061 Trpc5 Positive_regulation of Gene_expression of Ca2 1 0.08 0.06 0
31 INT192042 Binding of Jup and Ryr2 1 0.17 1.09 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for calcium channel complex. They are ordered first by their pain relevance and then by number of times they were reported in calcium channel complex. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT36715 Gene_expression of Trpc4 50 0.68 4.18 11.13
2 INT127978 Gene_expression of Trpc5 58 0.67 3.11 10.21
3 INT209301 Positive_regulation of Gene_expression of Trpc5 8 0.43 0.27 1.94
4 INT209307 Positive_regulation of Gene_expression of Trpc4 1 0.58 0.59 1.52
5 INT114822 Negative_regulation of PPP2R4 2 0.57 1.89 1.28
6 INT142777 Phosphorylation of PPP2R4 2 0.61 1.03 1.07
7 INT142776 Positive_regulation of Phosphorylation of PPP2R4 1 0.45 1.04 1.07
8 INT107874 Positive_regulation of Trpc4 3 0.58 0.09 1.02
9 INT209306 Regulation of Gene_expression of Trpc5 5 0.39 0.24 0.8
10 INT209285 Binding of Trpc5 3 0.32 0.49 0.8
11 INT209283 Positive_regulation of Trpc5 5 0.60 0.14 0.77
12 INT129556 Transcription of Trpc4 3 0.60 0.23 0.76
13 INT209286 Negative_regulation of Trpc5 8 0.50 1.24 0.69
14 INT209289 Localization of Trpc5 1 0.69 0 0.58
15 INT209298 Regulation of Gene_expression of Trpc4 1 0.38 0.17 0.54
16 INT209287 Transcription of Trpc5 1 0.62 0.16 0.48
17 INT209292 Negative_regulation of Gene_expression of Trpc5 1 0.50 0.07 0.47
18 INT192006 Gene_expression of RYR2 5 0.23 7.69 0.44
19 INT209281 Binding of Trpc4 3 0.31 0.22 0.41
20 INT8921 Negative_regulation of Trpc4 3 0.36 0.18 0.33
21 INT131151 Regulation of TRPC4 1 0.26 0.42 0.29
22 INT209294 Regulation of Trpc4 1 0.23 0.12 0.29
23 INT209311 Positive_regulation of Regulation of Trpc4 1 0.39 0 0.29
24 INT209309 Regulation of Positive_regulation of Trpc4 1 0.23 0 0.29
25 INT209277 Localization of Trpc4 1 0.63 0.24 0.27
26 INT196097 Gene_expression of Trpc5 3 0.54 0.18 0.26
27 INT209278 Negative_regulation of Gene_expression of Trpc4 1 0.36 0.13 0.26
28 INT120216 Regulation of RYR2 2 0.28 1.03 0.22
29 INT196101 Transcription of Trpc5 1 0.55 0.13 0.22
30 INT209300 Regulation of Trpc5 2 0.39 0.13 0.2
31 INT309759 Transcription of TRPC5 1 0.22 0 0.16
32 INT196103 Localization of Trpc5 1 0.62 0 0.16
33 INT209303 Positive_regulation of Transcription of Trpc5 1 0.43 0 0.16
34 INT78375 Localization of PPP2R4 1 0.73 0.43 0.14
35 INT165787 Positive_regulation of RYR2 2 0.23 1.3 0.11
36 INT329999 Binding of AKAP6 1 0.36 0.91 0.07
37 INT192016 Localization of RYR2 5 0.25 4.18 0.05
38 INT192012 Binding of RYR2 2 0.30 3.61 0.05
39 INT221865 Positive_regulation of Localization of RYR2 2 0.15 4.56 0.05
40 INT8925 Positive_regulation of Negative_regulation of Trpc4 1 0.08 0.18 0.05
41 INT192023 Negative_regulation of RYR2 1 0.15 1.86 0.04
42 INT209276 Regulation of Transcription of Trpc5 1 0.39 0 0.03
43 INT209288 Regulation of Transcription of Trpc4 1 0.38 0 0.03
44 INT322462 Transcription of Ryr2 1 0.55 0.47 0.03
45 INT219581 Binding of Ryr2 2 0.27 4.54 0
46 INT219567 Phosphorylation of Ryr2 2 0.62 0.22 0
47 INT276521 Binding of Trpc5 1 0.18 0.25 0
48 INT329998 Localization of AKAP6 1 0.72 0.26 0
49 INT219566 Localization of Ryr2 1 0.45 0.49 0
50 INT330002 Gene_expression of AKAP6 1 0.75 0.11 0
51 INT329944 Negative_regulation of Gene_expression of Trpc5 1 0.30 0.18 0
52 INT293342 Regulation of PPP2R4 1 0.03 0 0
53 INT329942 Negative_regulation of Trpc5 1 0.41 0.16 0
54 INT322461 Negative_regulation of Transcription of Ryr2 1 0.45 0 0
55 INT219582 Positive_regulation of Phosphorylation of Ryr2 1 0.30 0.22 0
56 INT192020 Regulation of Localization of RYR2 1 0.15 0.27 0
57 INT209304 Regulation of Regulation of Trpc4 1 0.20 0.06 0
58 INT329941 Regulation of Trpc5 1 0.19 0.12 0
59 INT297204 Regulation of Ryr2 1 0.08 0.3 0
60 INT249252 Gene_expression of TRPC4 1 0.44 0 0
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