GO:0034959

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Name endothelin maturation
Categary Process
Go Slim No
Go Link GO:0034959
Unique Molecular Interactions 14
Total Molecular Interactions 25
Total Single Events 106
Pain Genes Associated 3

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for endothelin maturation. They are ordered first by their pain relevance and then by number of times they were reported for endothelin maturation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT95275 Binding of Edn1 and Ece1 1 0.32 2.09 1.3
2 INT95274 Regulation of Binding of Edn1 and Ece1 1 0.39 2.09 1.3
3 INT161796 Binding of ECE1 and EDN1 2 0.21 2.23 0.34
4 INT67266 Edn1 Negative_regulation of Ece1 1 0.19 0.17 0.32
5 INT191501 NLRP3 Positive_regulation of ECE1 1 0.01 1.09 0.28
6 INT191495 NLRP3 Positive_regulation of Protein_catabolism of ECE1 1 0.01 1.09 0.28
7 INT161797 Binding of ECE1 and ING1 1 0.01 0.68 0.14
8 INT324898 Ece1 Regulation of Gene_expression of Edn1 1 0.17 0.8 0.14
9 INT161795 Positive_regulation of Binding of ECE1 and ING1 1 0.02 0.68 0.14
10 INT161799 Positive_regulation of Binding of ECE1 and EDN1 1 0.07 0.68 0.14
11 INT324896 Ece1 Positive_regulation of Negative_regulation of Edn1 1 0.19 0.42 0.07

Single Events

The table below shows the top 100 pain related interactions that have been reported for endothelin maturation. They are ordered first by their pain relevance and then by number of times they were reported in endothelin maturation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT37294 Negative_regulation of Ece1 6 0.54 1.27 1.74
2 INT92955 Gene_expression of Ece1 5 0.74 2.2 1.36
3 INT92954 Positive_regulation of Gene_expression of Ece1 2 0.48 2.16 1.32
4 INT95270 Regulation of Ece1 1 0.43 2.08 1.3
5 INT87233 Gene_expression of ECE1 12 0.65 3.54 1.12
6 INT297531 Negative_regulation of Ece1 5 0.32 5.49 0.87
7 INT268451 Positive_regulation of Gene_expression of ECE1 3 0.49 1.99 0.67
8 INT88705 Localization of Ece1 2 0.22 2.07 0.55
9 INT87230 Localization of ECE1 5 0.80 1.51 0.53
10 INT329319 Positive_regulation of Transcription of Ece1 1 0.08 2.64 0.48
11 INT93926 Gene_expression of Ece1 3 0.27 2.31 0.42
12 INT324886 Transcription of Ece1 2 0.37 1.95 0.4
13 INT61124 Localization of Ece1 1 0.58 0.08 0.32
14 INT191535 Protein_catabolism of ECE1 1 0.07 1.03 0.28
15 INT329320 Positive_regulation of Gene_expression of Ece1 1 0.09 1.31 0.24
16 INT324884 Positive_regulation of Ece1 2 0.37 0.86 0.22
17 INT324882 Regulation of Transcription of Ece1 1 0.24 0.66 0.19
18 INT87231 Binding of ECE1 4 0.37 0.47 0.16
19 INT161805 Positive_regulation of ECE1 1 0.12 0.61 0.13
20 INT87232 Regulation of ECE1 1 0.45 0.16 0.1
21 INT49260 Negative_regulation of ECE1 7 0.57 0.24 0.08
22 INT126436 Regulation of Gene_expression of Ece1 1 0.21 0.05 0.05
23 INT255789 Protein_catabolism of Ece1 2 0.35 1.06 0
24 INT226248 Negative_regulation of Negative_regulation of ECE1 1 0.05 0 0
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