GO:0035022

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Name positive regulation of Rac protein signal transduction
Categary Process
Go Slim No
Go Link GO:0035022
Unique Molecular Interactions 73
Total Molecular Interactions 92
Total Single Events 674
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of Rac protein signal transduction. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of Rac protein signal transduction. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT121698 HRAS Negative_regulation of Gene_expression of MMP3 1 0.06 0.5 2.6
2 INT247281 GLC1N Negative_regulation of HRAS 1 0.02 1.98 1.62
3 INT166790 HRAS Negative_regulation of Gene_expression of PTGER1 1 0.01 1.46 0.95
4 INT121702 HRAS Negative_regulation of Positive_regulation of MMP1 1 0.06 0.2 0.9
5 INT121701 HRAS Negative_regulation of MMP1 1 0.06 0.2 0.89
6 INT121704 HRAS Negative_regulation of MMP3 1 0.06 0.19 0.89
7 INT121699 HRAS Negative_regulation of Gene_expression of MMP1 1 0.06 0.19 0.88
8 INT121966 HRAS Positive_regulation of RAC1 1 0.75 0.41 0.67
9 INT184193 HRAS Negative_regulation of Gene_expression of IL1B 1 0.00 1.12 0.65
10 INT247285 GLC1N Positive_regulation of Gene_expression of HRAS 1 0.02 1.3 0.61
11 INT155881 Binding of CDX2 and KRAS 1 0.40 1.51 0.47
12 INT95564 Positive_regulation of HRAS Positive_regulation of IL12A 1 0.03 0.7 0.45
13 INT95562 HRAS Positive_regulation of IL12A 1 0.03 0.7 0.45
14 INT95563 HRAS Positive_regulation of TNF 1 0.03 0.7 0.45
15 INT169466 TGFB3 Positive_regulation of HRAS 1 0.03 0.89 0.43
16 INT346218 Positive_regulation of Kras Positive_regulation of Phosphorylation of Mdk 1 0.01 0.71 0.42
17 INT247287 Gene_expression of GLC1N Regulation of Gene_expression of HRAS 1 0.02 0.56 0.42
18 INT351237 HRAS Regulation of CBL 1 0.00 0.48 0.4
19 INT166788 HRAS Negative_regulation of Phosphorylation of NFKB1 1 0.08 0.5 0.39
20 INT166792 Binding of CD44 and HRAS 3 0.12 1.49 0.37
21 INT257741 HRAS Negative_regulation of PTEN 1 0.15 1.06 0.35
22 INT257737 Positive_regulation of HRAS Negative_regulation of PTEN 1 0.17 1.07 0.35
23 INT166789 HRAS Regulation of Positive_regulation of NFKB1 1 0.05 0.31 0.3
24 INT265467 HRAS Negative_regulation of Gene_expression of PTGS2 1 0.01 0.84 0.29
25 INT346220 Binding of Kras and Braf 1 0.03 0.58 0.28
26 INT60347 COL2A1 Positive_regulation of Gene_expression of Hras 1 0.05 0.92 0.2
27 INT184194 Binding of HRAS and SPAM1 1 0.00 0.26 0.17
28 INT293697 Dock2 Positive_regulation of Akt1 1 0.14 0.08 0.13
29 INT262618 Binding of SOAT1 and Kras 1 0.00 0.81 0.12
30 INT247280 GLC1N Regulation of Gene_expression of HRAS 1 0.03 0.29 0.12
31 INT173122 PPA1 Positive_regulation of HRAS 1 0.08 0.5 0.12
32 INT83370 Binding of HRAS and TP53 1 0.30 0.59 0.11
33 INT293417 HRAS Regulation of IL11 1 0.00 1.17 0.1
34 INT293414 HRAS Regulation of PTHLH 1 0.00 1.18 0.1
35 INT293408 HRAS Regulation of VEGFA 1 0.00 1.18 0.1
36 INT351426 SEPT5 Regulation of HRAS 1 0.00 0.7 0.09
37 INT351425 HRAS Regulation of SEPT5 1 0.00 0.7 0.09
38 INT293415 HRAS Positive_regulation of Localization of IL8 1 0.01 0.73 0.09
39 INT84751 Binding of HRAS and TWIST1 1 0.29 2.6 0.07
40 INT84752 Binding of HRAS and DCPS 1 0.18 2.61 0.07
41 INT172980 Binding of VEGFA and Kras 1 0.00 0.79 0
42 INT232057 Binding of KRAS and RNPC3 1 0.00 0.31 0
43 INT320959 Binding of HRAS and HMHA1 1 0.00 0.37 0
44 INT215698 Lamtor1 Negative_regulation of Kras 1 0.00 0 0
45 INT320712 Binding of NRAS and PIK3CD 1 0.21 1.66 0
46 INT264683 Binding of VAPB and ALS2 1 0.29 1.1 0
47 INT350426 Binding of BRAF and KRAS 1 0.05 1.78 0
48 INT320713 NRAS Positive_regulation of AKT1 1 0.37 0.84 0
49 INT268397 Binding of Kras and Regulation of ARAF 1 0.03 1.16 0
50 INT180666 Fn1 Regulation of Transcription of Kras 1 0.31 0 0
51 INT272859 Binding of HRAS and M1 1 0.00 0.33 0
52 INT232051 Binding of FOXM1 and KRAS 1 0.00 0.63 0
53 INT180669 Fn1 Regulation of Kras 1 0.18 0 0
54 INT215696 Cdkn2a Negative_regulation of Kras 1 0.00 0 0
55 INT215702 Stmn1 Negative_regulation of Kras 1 0.00 0 0
56 INT320715 NRAS Positive_regulation of PIK3CD 1 0.27 1.66 0
57 INT319319 Binding of EGFR and KRAS 1 0.22 0.27 0
58 INT268395 Binding of APC and Kras 1 0.04 1.21 0
59 INT215688 Cdkn2b Negative_regulation of Kras 1 0.00 0 0
60 INT350433 KRAS Regulation of Gene_expression of BRAF 1 0.08 1.77 0
61 INT293410 HRAS Regulation of Localization of SPP1 1 0.00 0.8 0
62 INT258716 Camk1g Positive_regulation of Kras 1 0.02 0.08 0
63 INT215703 Binding of Kras and Cdk6 1 0.01 0 0
64 INT247282 GLC1N Positive_regulation of HRAS 1 0.02 0.14 0
65 INT265547 Positive_regulation of Tp53 Positive_regulation of Gene_expression of Kras 1 0.01 0.93 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of Rac protein signal transduction. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of Rac protein signal transduction. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT28216 Gene_expression of HRAS 173 0.75 93.97 20.78
2 INT63113 Positive_regulation of HRAS 30 0.67 22.85 4.28
3 INT20981 Binding of HRAS 42 0.48 24.49 4.23
4 INT80175 Positive_regulation of Gene_expression of HRAS 24 0.67 14.69 3.97
5 INT169475 Localization of HRAS 14 0.73 9.02 3.9
6 INT53706 Positive_regulation of Kras 13 0.67 9.26 3.57
7 INT62683 Negative_regulation of HRAS 19 0.57 7.93 2.65
8 INT111039 Gene_expression of Kras 20 0.60 15.42 2.39
9 INT76993 Regulation of HRAS 8 0.60 7.81 1.95
10 INT109975 Positive_regulation of Kras 14 0.45 12.72 1.68
11 INT93624 Negative_regulation of Kras 3 0.41 1.15 1.52
12 INT184206 Protein_catabolism of HRAS 22 0.66 7.86 1.46
13 INT92383 Gene_expression of KRAS 38 0.65 32.94 1.32
14 INT60060 Positive_regulation of KRAS 17 0.67 11.68 1.21
15 INT166171 Negative_regulation of Gene_expression of HRAS 5 0.07 3.98 1.11
16 INT247294 Regulation of Gene_expression of HRAS 1 0.04 1.8 1.02
17 INT204058 Regulation of Gene_expression of Kras 4 0.24 7.54 1.01
18 INT111035 Positive_regulation of Gene_expression of Kras 5 0.31 3.31 0.99
19 INT36887 Regulation of Hras 2 0.44 0.76 0.72
20 INT92382 Positive_regulation of Gene_expression of KRAS 7 0.49 4.82 0.71
21 INT60343 Gene_expression of Hras 6 0.75 2.3 0.64
22 INT93622 Positive_regulation of Negative_regulation of Kras 1 0.49 0.49 0.61
23 INT144700 Gene_expression of Kras 21 0.41 12.28 0.57
24 INT82167 Transcription of HRAS 4 0.67 3.8 0.53
25 INT92384 Regulation of Positive_regulation of HRAS 2 0.60 2.05 0.48
26 INT169470 Positive_regulation of Localization of HRAS 1 0.49 0.89 0.43
27 INT60346 Positive_regulation of Gene_expression of Hras 4 0.42 1.56 0.4
28 INT98708 Binding of KRAS 13 0.47 7.47 0.39
29 INT98203 Negative_regulation of KRAS 5 0.42 2.38 0.34
30 INT60342 Negative_regulation of Gene_expression of Hras 2 0.56 0.6 0.31
31 INT247292 Positive_regulation of Positive_regulation of HRAS 1 0.03 0.62 0.31
32 INT196913 Regulation of Kras 3 0.10 3.81 0.28
33 INT114788 Negative_regulation of Positive_regulation of Kras 1 0.04 0.65 0.28
34 INT29141 Binding of Kras 3 0.15 0.81 0.27
35 INT82373 Positive_regulation of Regulation of HRAS 1 0.25 1.49 0.25
36 INT117439 Negative_regulation of Positive_regulation of Kras 1 0.42 1.31 0.2
37 INT348917 Negative_regulation of Protein_catabolism of HRAS 1 0.02 0.57 0.2
38 INT60345 Regulation of Gene_expression of Hras 1 0.44 0.36 0.15
39 INT184200 Positive_regulation of Protein_catabolism of HRAS 1 0.01 0.45 0.13
40 INT214943 Negative_regulation of Gene_expression of Kras 2 0.13 0.05 0.12
41 INT127918 Negative_regulation of Kras 2 0.17 0.66 0.08
42 INT326201 Positive_regulation of Gene_expression of Kras 2 0.02 1.06 0.08
43 INT331321 Protein_catabolism of KRAS 1 0.07 0.97 0.08
44 INT127916 Localization of Kras 1 0.29 0 0.08
45 INT142555 Positive_regulation of Positive_regulation of Kras 1 0.35 0.6 0.07
46 INT207240 Regulation of Gene_expression of KRAS 2 0.28 1.31 0.06
47 INT294235 Negative_regulation of Binding of KRAS 1 0.05 0 0.05
48 INT207233 Transcription of KRAS 3 0.48 1.56 0.03
49 INT206135 Positive_regulation of NRAS 2 0.62 2.23 0.03
50 INT348616 Negative_regulation of Gene_expression of KRAS 1 0.31 0.34 0.03
51 INT236621 Regulation of KRAS 7 0.53 6.16 0
52 INT180396 Localization of KRAS 3 0.69 2.89 0
53 INT304076 Regulation of Localization of KRAS 2 0.36 2.39 0
54 INT175421 Positive_regulation of Positive_regulation of KRAS 2 0.34 1.45 0
55 INT320736 Binding of NRAS 1 0.32 0.82 0
56 INT315376 Negative_regulation of Binding of Kras 1 0.04 0.12 0
57 INT293418 Regulation of Binding of HRAS 1 0.01 1.18 0
58 INT178925 Negative_regulation of Gene_expression of Kras 1 0.07 1.34 0
59 INT300382 Regulation of NRAS 1 0.13 2.42 0
60 INT180701 Negative_regulation of Hras 1 0.04 0 0
61 INT268347 Binding of Kras 1 0.06 2.44 0
62 INT180682 Transcription of Kras 1 0.67 0 0
63 INT326200 Regulation of Gene_expression of Kras 1 0.03 0 0
64 INT326199 Phosphorylation of Kras 1 0.04 0 0
65 INT320721 Protein_catabolism of NRAS 1 0.59 0.89 0
66 INT315374 Regulation of Kras 1 0.02 0.24 0
67 INT268346 Positive_regulation of Binding of Kras 1 0.08 1.41 0
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