GO:0035024

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Name negative regulation of Rho protein signal transduction
Categary Process
Go Slim No
Go Link GO:0035024
Unique Molecular Interactions 21
Total Molecular Interactions 21
Total Single Events 498
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of Rho protein signal transduction. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of Rho protein signal transduction. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT54853 Negative_regulation of Adra1a Positive_regulation of Positive_regulation of Ins1 1 0.18 0.23 1
2 INT54852 Negative_regulation of Adra1a Positive_regulation of Ins1 1 0.18 0.23 0.99
3 INT79809 Binding of Agtr1a and Adra1a 1 0.02 0.23 0.53
4 INT47101 Adra1a Regulation of Localization of Gnrhr 1 0.02 0.24 0.44
5 INT275849 PES1 Positive_regulation of Gene_expression of TNFAIP1 1 0.01 1.28 0.42
6 INT126531 Adra1a Positive_regulation of Serpine1 1 0.03 0.31 0.34
7 INT44654 Phc1 Negative_regulation of Adra1a 1 0.00 0.4 0.33
8 INT59326 Binding of Adra1a and Positive_regulation of Binding of Npy 1 0.44 0 0.31
9 INT143688 Binding of Dlc1 and Trpv1 1 0.01 0.45 0.3
10 INT148345 Binding of Drd3 and Adra1a 1 0.18 0.12 0.21
11 INT350700 Binding of Bcl6 and thd 1 0.00 0.21 0.08
12 INT243309 TNFAIP1 Positive_regulation of Localization of TNF 1 0.07 0.71 0.08
13 INT350692 Binding of Bcl6 and Hand1 1 0.02 0.16 0.08
14 INT350720 Binding of Bcl6 and TBX21 1 0.07 0.22 0.08
15 INT243313 TNFAIP1 Positive_regulation of TNF 1 0.31 0.71 0.08
16 INT327451 HTN1 Positive_regulation of Adra1a 1 0.00 1.36 0.03
17 INT305986 Binding of Nfe2l2 and Cul3 1 0.39 0.44 0
18 INT207266 INS Negative_regulation of BCL6 1 0.29 0.08 0
19 INT322470 Binding of Bcl6 and Hif1a 1 0.06 0.52 0
20 INT305632 Binding of BCL6 and MME 1 0.00 1.37 0
21 INT268508 MIR221 Positive_regulation of BCL6 1 0.03 1.36 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of Rho protein signal transduction. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of Rho protein signal transduction. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT18658 Regulation of Adra1a 34 0.62 5.69 13.78
2 INT44 Positive_regulation of Adra1a 30 0.68 7.09 12.73
3 INT14124 Negative_regulation of Adra1a 34 0.59 7.48 10.85
4 INT348 Regulation of Adra1a 25 0.45 3.33 10.27
5 INT475 Negative_regulation of Adra1a 28 0.58 7.87 9.83
6 INT7697 Positive_regulation of Adra1a 22 0.68 2.3 9.16
7 INT2280 Negative_regulation of TNFAIP1 70 0.43 69.43 8.36
8 INT1448 Binding of Adra1a 23 0.48 1.41 8.01
9 INT7842 Gene_expression of Adra1a 14 0.67 1.99 6.39
10 INT335 Binding of Adra1a 16 0.36 6.16 6
11 INT29394 Gene_expression of Adra1a 9 0.77 3.62 3.91
12 INT15211 Localization of Adra1a 3 0.16 0 2.08
13 INT45 Negative_regulation of Positive_regulation of Adra1a 4 0.43 0.84 1.97
14 INT275860 Negative_regulation of Localization of TNFAIP1 1 0.03 4.41 1.91
15 INT3911 Gene_expression of TNFAIP1 29 0.65 21.68 1.85
16 INT126457 Gene_expression of BCL6 34 0.66 22.45 1.75
17 INT29395 Positive_regulation of Gene_expression of Adra1a 2 0.50 1.64 1.57
18 INT243339 Localization of TNFAIP1 4 0.41 3.7 1.39
19 INT14803 Positive_regulation of Positive_regulation of Adra1a 4 0.35 0.49 1.36
20 INT125157 Negative_regulation of Gene_expression of Adra1a 1 0.18 0.54 0.8
21 INT181326 Binding of TNFAIP1 2 0.29 0.81 0.74
22 INT6734 Localization of Adra1a 3 0.31 0.25 0.67
23 INT230410 Negative_regulation of Gene_expression of TNFAIP1 3 0.16 3.67 0.63
24 INT163857 Gene_expression of Dlc1 1 0.03 0.17 0.6
25 INT236711 Gene_expression of Bcl6 15 0.30 12.98 0.58
26 INT18657 Negative_regulation of Binding of Adra1a 2 0.43 0.17 0.56
27 INT56708 Positive_regulation of Positive_regulation of Adra1a 1 0.25 0 0.55
28 INT181325 Positive_regulation of TNFAIP1 4 0.36 4.64 0.52
29 INT13738 Negative_regulation of Positive_regulation of Adra1a 3 0.29 0.08 0.52
30 INT21090 Regulation of Negative_regulation of Adra1a 1 0.18 0.35 0.52
31 INT207299 Binding of BCL6 6 0.30 3.5 0.41
32 INT66593 Regulation of Gene_expression of Adra1a 2 0.05 0 0.39
33 INT102164 Positive_regulation of Binding of Adra1a 1 0.35 0.19 0.37
34 INT34162 Regulation of Regulation of Adra1a 1 0.02 0 0.36
35 INT143687 Positive_regulation of Dlc1 1 0.01 0.46 0.34
36 INT121388 Positive_regulation of BCL6 2 0.28 2.71 0.32
37 INT235466 Localization of BCL6 3 0.27 5 0.29
38 INT44623 Positive_regulation of Regulation of Adra1a 1 0.04 0.64 0.29
39 INT42351 Regulation of Positive_regulation of Adra1a 1 0.01 0 0.26
40 INT118118 Positive_regulation of Binding of Adra1a 1 0.18 0.3 0.26
41 INT122590 Transcription of Adra1a 1 0.03 0.73 0.24
42 INT39288 Regulation of Binding of Adra1a 1 0.20 0.35 0.2
43 INT20828 Positive_regulation of Negative_regulation of TNFAIP1 1 0.36 0.1 0.19
44 INT144881 Positive_regulation of Gene_expression of BCL6 5 0.43 1.6 0.18
45 INT31927 Positive_regulation of Localization of Adra1a 1 0.10 0.17 0.16
46 INT236693 Positive_regulation of Gene_expression of Bcl6 3 0.15 2.06 0.14
47 INT258953 Negative_regulation of Gene_expression of Bcl6 1 0.19 1.53 0.14
48 INT181323 Regulation of TNFAIP1 4 0.35 0.92 0.11
49 INT258955 Localization of Bcl6 1 0.23 0.83 0.11
50 INT350635 Transcription of Bcl6 1 0.09 0.16 0.08
51 INT350649 Negative_regulation of Transcription of Bcl6 1 0.06 0.16 0.08
52 INT125793 Protein_catabolism of Adra1a 1 0.39 0.24 0.05
53 INT207276 Transcription of BCL6 3 0.45 0.64 0.03
54 INT144882 Negative_regulation of Gene_expression of BCL6 2 0.26 0.93 0
55 INT322454 Positive_regulation of Bcl6 2 0.10 1.6 0
56 INT181322 Positive_regulation of Gene_expression of TNFAIP1 2 0.39 3.28 0
57 INT207269 Regulation of BCL6 1 0.38 0.1 0
58 INT181324 Regulation of Gene_expression of TNFAIP1 1 0.35 0 0
59 INT277796 Binding of Bcl6 1 0.17 1.33 0
60 INT347438 Regulation of Gene_expression of BCL6 1 0.07 0.7 0
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