GO:0035035

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Name histone acetyltransferase binding
Categary Function
Go Slim No
Go Link GO:0035035
Unique Molecular Interactions 518
Total Molecular Interactions 626
Total Single Events 5736
Pain Genes Associated 27

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for histone acetyltransferase binding. They are ordered first by their pain relevance and then by number of times they were reported for histone acetyltransferase binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT206768 TP53 Positive_regulation of Ltp 2 0.01 5.83 10.21
2 INT227493 Binding of TCEA1 and SIRT2 1 0.01 1.55 1.93
3 INT157540 Binding of SP1 and YY1 1 0.41 2.55 1.42
4 INT229913 Positive_regulation of Ntsr1 Positive_regulation of Gene_expression of Egr1 1 0.12 1.33 1.11
5 INT134970 Positive_regulation of Binding of OPRK1 and SP1 1 0.00 0 1.05
6 INT134969 Binding of OPRK1 and SP1 1 0.00 0 1.04
7 INT229914 Egr1 Positive_regulation of Phosphorylation of Mapk3 1 0.46 1.03 1.02
8 INT61860 Akr1d1 Regulation of Egr1 1 0.01 0 0.96
9 INT73461 PTPLA Positive_regulation of Transcription of TP53 1 0.06 0.99 0.96
10 INT61861 Akr1d1 Regulation of Positive_regulation of Egr1 1 0.01 0 0.96
11 INT330629 TP53 Negative_regulation of Gene_expression of Fos 1 0.30 1.76 0.94
12 INT61859 Akr1d1 Positive_regulation of Egr1 1 0.01 0 0.92
13 INT61862 Slc3a1 Positive_regulation of Egr1 1 0.05 0 0.92
14 INT77254 Binding of gr and Sp1 1 0.04 0.4 0.9
15 INT103611 Mdk Negative_regulation of Phosphorylation of Sp1 1 0.01 0.28 0.88
16 INT116107 CDK4 Positive_regulation of Phosphorylation of EID1 1 0.01 0.32 0.86
17 INT330630 Binding of TP53 and Car1 1 0.23 1.56 0.86
18 INT140985 Gli3 Regulation of Ihh 1 0.29 0.85 0.85
19 INT97057 Bcl2l1 Regulation of Gene_expression of Trp53 1 0.36 0.51 0.83
20 INT97058 Cpz Regulation of Gene_expression of Trp53 1 0.27 0.57 0.83
21 INT314203 Nos2 Positive_regulation of Gli3 1 0.19 1.27 0.73
22 INT157539 Binding of SP1 and Regulation of Gene_expression of OPRM1 1 0.36 1.2 0.72
23 INT123494 Binding of Egr1 and Ccr5 1 0.04 0.94 0.71
24 INT98956 Positive_regulation of Binding of NR5A2 and SP1 1 0.00 0 0.7
25 INT207542 Sp1 Regulation of Oprm1 1 0.15 0.06 0.7
26 INT98958 Binding of NR5A2 and SP1 1 0.00 0 0.7
27 INT68561 Binding of Gli3 and Ust 1 0.01 0.68 0.68
28 INT92025 Egr1 Positive_regulation of Jun 1 0.15 0.61 0.67
29 INT92026 Egr1 Positive_regulation of Fos 1 0.50 0.61 0.67
30 INT207547 Sp1 Regulation of Qsox1 1 0.05 0.06 0.67
31 INT101986 TP53 Positive_regulation of Gene_expression of GDF15 1 0.52 2.45 0.67
32 INT312106 EGR1 Regulation of Gene_expression of PTGES 1 0.31 1.06 0.64
33 INT123416 Gene_expression of Sp1 Positive_regulation of Oprm1 1 0.60 0 0.63
34 INT100369 HIF1A Positive_regulation of Positive_regulation of VEGFA 1 0.29 0.99 0.62
35 INT98953 Positive_regulation of Binding of SP1 and CFHR4 1 0.00 0 0.62
36 INT98954 Binding of SP1 and CFHR4 1 0.00 0 0.61
37 INT98629 VEGFA Positive_regulation of Gene_expression of EGR1 1 0.52 0.42 0.61
38 INT98628 VEGFA Positive_regulation of Transcription of EGR1 1 0.52 0.42 0.61
39 INT166402 CDKN1A Regulation of Gene_expression of TP53 1 0.27 0.83 0.61
40 INT115146 MAPK1 Positive_regulation of EGR1 3 0.13 2.43 0.57
41 INT261478 Positive_regulation of Ephb1 Regulation of Gene_expression of Egr1 1 0.10 0.23 0.55
42 INT38422 Zbtb7a Positive_regulation of Pag1 1 0.30 0.66 0.54
43 INT254200 Mif Regulation of Trp53 1 0.02 0.96 0.52
44 INT135176 Myst2 Regulation of Gene_expression of Hif1a 1 0.24 0.47 0.47
45 INT254360 Binding of EPAS1 and HIF1A 3 0.39 3.36 0.46
46 INT227495 Regulation of Binding of TCEA1 and SIRT2 1 0.01 0.45 0.45
47 INT135178 Myst2 Regulation of Hif1a 1 0.24 0.44 0.44
48 INT302829 Mapkapk5 Positive_regulation of Trp53 1 0.07 0.81 0.43
49 INT292634 IL4 Positive_regulation of Gene_expression of FOXP3 1 0.10 0.42 0.43
50 INT89332 Binding of SP1 and SP3 1 0.30 0.76 0.39
51 INT45797 ZBTB7A Regulation of Lhb 1 0.36 0.09 0.38
52 INT130930 Egr1 Negative_regulation of Positive_regulation of Thbs1 1 0.58 0.64 0.38
53 INT167558 Gene_expression of Sp1 Positive_regulation of Oprm1 1 0.03 0.07 0.36
54 INT123495 Negative_regulation of Binding of Egr1 and Ccr5 1 0.03 0.48 0.36
55 INT123493 Regulation of Binding of Egr1 and Ccr5 1 0.03 0.48 0.36
56 INT90722 Nr4a1 Positive_regulation of Egr1 1 0.20 0.48 0.35
57 INT312124 EGR1 Regulation of Binding of PTGES 1 0.31 0.41 0.35
58 INT90723 Nr4a2 Positive_regulation of Egr1 1 0.22 0.49 0.35
59 INT200333 Binding of Rest and Sp1 1 0.24 0.07 0.35
60 INT90724 Egr3 Positive_regulation of Egr1 1 0.33 0.48 0.35
61 INT200316 Sp1 Regulation of Gene_expression of Rest 1 0.31 0 0.35
62 INT144966 MAPK1 Positive_regulation of Localization of EGR1 1 0.08 0.83 0.35
63 INT198647 TNF Positive_regulation of HIF1A 1 0.03 2.97 0.34
64 INT91814 Binding of TNF and TP53 1 0.14 2.2 0.32
65 INT126097 Ddc Positive_regulation of Egr1 1 0.08 0 0.32
66 INT166394 CDKN1B Regulation of Gene_expression of TP53 1 0.28 0.41 0.31
67 INT166396 IFI27 Regulation of Gene_expression of TP53 1 0.19 0.41 0.31
68 INT200351 Sp1 Positive_regulation of Gene_expression of Rest 1 0.34 0.07 0.3
69 INT333917 MDM2 Positive_regulation of Protein_catabolism of Trp53 1 0.01 1.23 0.3
70 INT333918 HDAC1 Regulation of Trp53 1 0.03 1.24 0.3
71 INT163761 MDM2 Positive_regulation of Gene_expression of TP53 1 0.40 0.86 0.3
72 INT74334 Penk Regulation of Transcription of Egr1 1 0.40 0.25 0.29
73 INT166952 LYRM4 Positive_regulation of Gene_expression of TP53 1 0.05 0.75 0.28
74 INT74336 Crh Regulation of Transcription of Egr1 1 0.49 0.24 0.28
75 INT147356 Egr1 Positive_regulation of Gene_expression of Btg1 1 0.14 1.56 0.28
76 INT286042 Binding of Tp53 and Wwox 1 0.04 2.05 0.28
77 INT216127 EGR1 Regulation of Transcription of TP53 1 0.06 0.21 0.28
78 INT147358 Egr1 Positive_regulation of Gene_expression of Gdf15 1 0.14 1.56 0.28
79 INT302837 Binding of TNFRSF10D and Trp53 1 0.01 0.98 0.28
80 INT58182 Fos Regulation of Egr1 1 0.49 0.09 0.27
81 INT147359 Positive_regulation of Pik3cd Positive_regulation of Egr1 1 0.09 1.51 0.27
82 INT306267 Binding of INCENP and TP53 1 0.02 0.83 0.27
83 INT96789 Binding of SP1 and NR2F2 1 0.24 0.27 0.27
84 INT216128 EGR1 Regulation of TP53 1 0.11 0.21 0.27
85 INT130931 Sis Negative_regulation of Egr1 1 0.01 0.52 0.27
86 INT96787 SP1 Positive_regulation of GDF15 1 0.08 0.27 0.27
87 INT58176 Junb Regulation of Egr1 1 0.46 0.09 0.27
88 INT147360 Pik3cd Positive_regulation of Egr1 1 0.12 1.51 0.27
89 INT125515 SP1 Regulation of GDF15 1 0.14 0.47 0.26
90 INT352931 Prkaca Regulation of TP53 1 0.13 1.01 0.26
91 INT352930 Prkaca Regulation of Phosphorylation of TP53 1 0.13 1.02 0.26
92 INT169837 Sp1 Positive_regulation of Gene_expression of Kcnq3 1 0.04 0.08 0.26
93 INT182325 TP53 Negative_regulation of Transcription of Birc5 1 0.01 1.34 0.26
94 INT126886 Protein_catabolism of SP1 Negative_regulation of Gene_expression of VEGFA 1 0.03 0.49 0.26
95 INT172975 Trp53 Positive_regulation of Cdkn1a 1 0.03 1.35 0.26
96 INT169836 Sp1 Positive_regulation of Gene_expression of Kcnq2 1 0.05 0.08 0.26
97 INT125521 EGR1 Regulation of GDF15 1 0.13 0.47 0.26
98 INT352893 PTGDS Regulation of TP53 1 0.16 1.02 0.26
99 INT125516 TP53 Regulation of GDF15 1 0.10 0.47 0.26
100 INT337086 Mif Negative_regulation of Localization of Trp53 1 0.16 1.64 0.25
101 INT337091 Mif Negative_regulation of Positive_regulation of Trp53 1 0.16 1.64 0.25
102 INT260739 Mapk14 Regulation of Positive_regulation of Sp1 1 0.01 1.06 0.25
103 INT198926 Binding of Apbb1 and Lrp1 5 0.12 2.18 0.24
104 INT156879 Gene_expression of TP53 Negative_regulation of Positive_regulation of PDF 1 0.45 0.9 0.24
105 INT181900 TP53 Negative_regulation of Gene_expression of NOS1 1 0.03 0.94 0.24
106 INT98631 Negative_regulation of VEGFA Positive_regulation of EGR1 1 0.44 0.18 0.24
107 INT130060 PPARG Positive_regulation of Positive_regulation of Egr1 1 0.22 0.46 0.24
108 INT98630 VEGFA Positive_regulation of EGR1 1 0.52 0.18 0.24
109 INT144967 MAPK1 Positive_regulation of Positive_regulation of EGR1 1 0.08 0.63 0.24
110 INT156881 TP53 Positive_regulation of Positive_regulation of PDF 1 0.49 0.89 0.24
111 INT229177 IFRD1 Regulation of TP53 1 0.13 0.68 0.23
112 INT254349 Positive_regulation of Binding of EPAS1 and HIF1A 1 0.00 0.92 0.23
113 INT184162 Egr1 Positive_regulation of Transcription of Ptges2 1 0.08 0.42 0.22
114 INT184160 Binding of Egr1 and Ptges2 1 0.07 0.4 0.22
115 INT226902 Padi3 Regulation of Trp53 1 0.06 0.69 0.22
116 INT162850 ISYNA1 Positive_regulation of Localization of HIF1A 1 0.05 0.25 0.21
117 INT229178 TP53 Regulation of ICAM1 1 0.07 0.9 0.21
118 INT156882 Binding of TP53 and PDF 1 0.39 0.77 0.21
119 INT189196 RASGRP1 Positive_regulation of SP1 1 0.05 0.63 0.21
120 INT271853 Ngf Positive_regulation of Gene_expression of Egr1 1 0.53 1.36 0.21
121 INT156880 TP53 Positive_regulation of Gene_expression of PDF 1 0.49 0.75 0.21
122 INT259817 Ltp Positive_regulation of Egr1 1 0.03 0.28 0.2
123 INT210887 Sst Positive_regulation of Gene_expression of Trp53 1 0.33 0.93 0.2
124 INT259812 Gtf3a Regulation of Egr1 1 0.01 0.58 0.19
125 INT184159 Egr1 Positive_regulation of Ptges2 1 0.07 0.34 0.19
126 INT136462 Negative_regulation of Ptgs1 Negative_regulation of Gene_expression of Sp1 1 0.01 0.65 0.19
127 INT58178 Gtf3a Positive_regulation of Egr1 1 0.07 0.09 0.19
128 INT184161 Negative_regulation of Egr1 Positive_regulation of Ptges2 1 0.07 0.34 0.19
129 INT259814 Binding of Arc and Egr1 1 0.34 0.55 0.19
130 INT259813 Binding of Egr1 and Arc 1 0.32 0.55 0.19
131 INT193787 Positive_regulation of CXCR4 Positive_regulation of Positive_regulation of TP53 1 0.03 0.71 0.19
132 INT142853 Binding of TP53 and WISP2 1 0.33 1.43 0.19
133 INT286965 Binding of STAT3 and FOXP3 1 0.27 1.84 0.19
134 INT149096 PITX2 Positive_regulation of Gene_expression of Egr1 1 0.01 1.23 0.19
135 INT58181 Gtf3a Positive_regulation of Gene_expression of Egr1 1 0.07 0.1 0.19
136 INT305003 HIF1A Regulation of SERPINE1 1 0.11 2.3 0.19
137 INT312090 EGR1 Regulation of Positive_regulation of PTGES 1 0.42 0.21 0.18
138 INT198649 Binding of HIF1A and MIF 1 0.01 1.53 0.18
139 INT317895 Fos Regulation of Transcription of Egr1 1 0.41 1.03 0.17
140 INT317897 Egr1 Regulation of Transcription of Fosb 1 0.34 1.08 0.17
141 INT102804 NFKB1 Regulation of TP53 1 0.35 0.77 0.17
142 INT317892 Egr1 Regulation of Transcription of Fos 1 0.41 1.03 0.17
143 INT143440 HIF1A Positive_regulation of Gene_expression of VEGFA 1 0.52 0.45 0.17
144 INT102803 NFKB1 Regulation of Gene_expression of TP53 1 0.35 0.77 0.17
145 INT312109 ELANE Positive_regulation of EGR1 1 0.15 0.23 0.16
146 INT296081 Binding of FOXP3 and Gtf3a 1 0.00 1.16 0.16
147 INT91812 Binding of FASLG and TP53 1 0.04 1.1 0.16
148 INT312100 ELANE Positive_regulation of Binding of EGR1 1 0.16 0.23 0.16
149 INT91811 Binding of FAS and TP53 1 0.21 1.1 0.16
150 INT296030 Binding of NFKB1 and FOXP3 1 0.17 1.18 0.16
151 INT146025 EGR1 Negative_regulation of Gene_expression of GDF15 1 0.28 0.81 0.15
152 INT181898 Binding of ROS1 and Positive_regulation of HIF1A 1 0.02 0.82 0.15
153 INT181897 ROS1 Negative_regulation of HIF1A 1 0.03 0.83 0.15
154 INT266377 Binding of S100a11 and Trp53 1 0.02 0.89 0.15
155 INT312092 ELANE Positive_regulation of Gene_expression of EGR1 1 0.19 0.21 0.15
156 INT237418 Binding of Hif1a and Bace1 1 0.06 1.18 0.15
157 INT296082 Binding of Rel and FOXP3 1 0.35 1.14 0.15
158 INT168806 Tlr4 Positive_regulation of Gene_expression of Egr1 1 0.18 0.3 0.15
159 INT181895 ROS1 Positive_regulation of HIF1A 1 0.03 0.78 0.15
160 INT311666 Binding of BCL2 and TP53 1 0.19 1.26 0.14
161 INT253564 Binding of Lpl and Sp1 1 0.13 0.9 0.14
162 INT115140 PPARG Positive_regulation of EGR1 1 0.36 0.45 0.13
163 INT103557 Binding of ERCC2 and TP53 1 0.40 1 0.13
164 INT181894 ROS1 Regulation of HIF1A 1 0.02 0.82 0.13
165 INT247267 Binding of Egr1 and Mecp2 1 0.12 0.18 0.13
166 INT132148 LTF Positive_regulation of TP53 1 0.44 0.56 0.13
167 INT321408 INS Positive_regulation of EGR1 1 0.03 2.36 0.13
168 INT288701 Epas1 Regulation of Transcription of Slc11a2 1 0.29 0.38 0.13
169 INT115141 TGM7 Positive_regulation of EGR1 1 0.26 0.44 0.13
170 INT103561 Binding of TP53 and Mc1r 1 0.03 1 0.13
171 INT323434 Osr1 Regulation of Hif1a 1 0.01 0.79 0.13
172 INT342311 Binding of Tp53 and Positive_regulation of Gene_expression of BCL2 1 0.08 1.25 0.13
173 INT198671 HIF1A Regulation of Positive_regulation of Epo 1 0.00 1.37 0.13
174 INT321414 INS Positive_regulation of Transcription of EGR1 1 0.03 2.36 0.13
175 INT323433 Osr1 Regulation of Protein_catabolism of Hif1a 1 0.01 0.8 0.13
176 INT200315 Binding of Sp1 and Sp3 1 0.29 0 0.12
177 INT220639 Binding of Apbb1 and Ighd 1 0.12 0.31 0.12
178 INT68802 Sp1 Regulation of Gene_expression of Pebp1 1 0.24 0 0.12
179 INT232787 CYBB Positive_regulation of Positive_regulation of Hif1a 1 0.01 0.66 0.12
180 INT321410 EGR1 Negative_regulation of Gene_expression of TNFSF10 1 0.10 2.07 0.12
181 INT323431 Binding of Hif1a and Vhl 1 0.07 0.68 0.12
182 INT249923 Binding of Pah and Hif1a 1 0.31 1.16 0.12
183 INT154803 Gene_expression of EGR1 Positive_regulation of Positive_regulation of GDF15 1 0.33 0.84 0.12
184 INT83370 Binding of HRAS and TP53 1 0.30 0.59 0.11
185 INT317891 Binding of Akt1 and Mtf1 1 0.21 1.04 0.11
186 INT253572 Binding of Csnk2a2 and Sp1 1 0.17 0 0.11
187 INT317896 Binding of Mmp9 and Mtf1 1 0.36 1.04 0.11
188 INT305002 Binding of HIF1A and SERPINE1 1 0.07 1.17 0.11
189 INT317887 Binding of Mtf1 and Pik3r1 1 0.25 1.04 0.11
190 INT199583 HIF1A Positive_regulation of Gene_expression of Vhl 1 0.26 1.39 0.11
191 INT266386 Binding of S100a1 and Trp53 1 0.03 0.64 0.1
192 INT286969 IL2 Regulation of Gene_expression of FOXP3 1 0.04 1.05 0.1
193 INT312305 Binding of HIF1A and Positive_regulation of Transcription of VEGFA 1 0.17 2.8 0.1
194 INT102244 IL36RN Positive_regulation of Binding of HIF1A 1 0.06 1.07 0.1
195 INT102245 TNF Positive_regulation of Binding of HIF1A 1 0.18 1.09 0.1
196 INT102248 INS Positive_regulation of Binding of HIF1A 1 0.13 0.96 0.1
197 INT294455 KLK4 Negative_regulation of HIF1A 1 0.01 0 0.1
198 INT171163 Creb1 Regulation of Sp1 1 0.03 0.62 0.1
199 INT194822 Negative_regulation of MAPK1 Negative_regulation of Binding of Sp1 1 0.04 0.05 0.1
200 INT193782 Binding of TP53 and SDF2L1 1 0.00 0.67 0.1

Single Events

The table below shows the top 100 pain related interactions that have been reported for histone acetyltransferase binding. They are ordered first by their pain relevance and then by number of times they were reported in histone acetyltransferase binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5861 Gene_expression of Egr1 203 0.78 49.35 68.13
2 INT5862 Positive_regulation of Egr1 82 0.70 30.4 33.96
3 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8
4 INT6054 Positive_regulation of Gene_expression of Egr1 67 0.70 18.45 25.93
5 INT57874 Gene_expression of Egr1 113 0.78 68.46 24.95
6 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71
7 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65
8 INT80972 Gene_expression of Tp53 104 0.78 102.74 16.02
9 INT41558 Localization of Sp1 9 0.48 0.56 14.9
10 INT105387 Gene_expression of HIF1A 116 0.77 98.62 14.66
11 INT57878 Positive_regulation of Gene_expression of Egr1 36 0.70 20.42 14.45
12 INT24082 Negative_regulation of Sp1 13 0.40 1.19 13.11
13 INT100379 Positive_regulation of HIF1A 69 0.69 57.31 10.4
14 INT49660 Positive_regulation of EGR1 54 0.69 32.17 9.89
15 INT169997 Positive_regulation of Gene_expression of Tp53 37 0.70 47.3 9.85
16 INT57876 Positive_regulation of Egr1 46 0.70 25.6 9.41
17 INT73021 Gene_expression of EGR1 43 0.77 24.65 9.18
18 INT155944 Gene_expression of Foxp3 66 0.66 24.37 9.12
19 INT169015 Gene_expression of FOXP3 50 0.60 33.18 8.4
20 INT6055 Transcription of Egr1 47 0.69 3.61 7.68
21 INT57748 Positive_regulation of Gene_expression of TP53 85 0.69 79.55 7.49
22 INT97055 Positive_regulation of Gene_expression of Trp53 51 0.70 45.7 7.25
23 INT6057 Negative_regulation of Gene_expression of Egr1 17 0.57 4.17 7.17
24 INT47707 Negative_regulation of Egr1 9 0.41 0.17 7.03
25 INT48555 Binding of SP1 30 0.46 11.38 6.53
26 INT73022 Positive_regulation of Gene_expression of EGR1 21 0.69 10.61 6.5
27 INT5860 Regulation of Gene_expression of Egr1 20 0.62 3.02 6.38
28 INT93359 Positive_regulation of Trp53 90 0.70 69.77 6.24
29 INT135170 Positive_regulation of Hif1a 86 0.67 99.4 6.07
30 INT112545 Phosphorylation of TP53 28 0.80 14.13 5.93
31 INT41604 Negative_regulation of Localization of Sp1 2 0.30 0.32 5.86
32 INT112713 Gene_expression of Hif1a 24 0.75 20.48 5.45
33 INT135172 Gene_expression of Hif1a 56 0.76 46.49 5.44
34 INT60585 Regulation of TP53 59 0.59 54.55 5.21
35 INT47704 Regulation of Egr1 17 0.60 2.43 5.18
36 INT47706 Negative_regulation of Positive_regulation of Egr1 9 0.41 6.11 5.1
37 INT68559 Negative_regulation of Gli3 5 0.37 4.56 4.93
38 INT57376 Transcription of EGR1 20 0.69 12.94 4.84
39 INT51944 Positive_regulation of Transcription of Egr1 12 0.49 1.96 4.72
40 INT109972 Phosphorylation of Trp53 13 0.80 6.15 4.68
41 INT62684 Negative_regulation of TP53 66 0.58 66.09 4.62
42 INT57749 Negative_regulation of Gene_expression of TP53 39 0.56 36.79 4.45
43 INT117936 Regulation of Gene_expression of Egr1 18 0.60 9.37 4.45
44 INT112704 Positive_regulation of Hif1a 25 0.67 21.49 4.23
45 INT123411 Gene_expression of Sp1 15 0.69 4.2 3.79
46 INT123502 Binding of Egr1 11 0.35 6.7 3.77
47 INT71602 Negative_regulation of Trp53 84 0.59 67.77 3.68
48 INT41559 Positive_regulation of Sp1 7 0.45 2.65 3.24
49 INT123409 Binding of Sp1 20 0.39 3.18 3.15
50 INT112365 Regulation of HIF1A 27 0.60 21.24 3.05
51 INT8103 Binding of TP53 46 0.44 40.2 2.96
52 INT103607 Binding of Sp1 7 0.42 1.26 2.92
53 INT105390 Positive_regulation of Gene_expression of HIF1A 27 0.49 26.3 2.88
54 INT93213 Phosphorylation of Sp1 5 0.67 0.93 2.84
55 INT134756 Positive_regulation of Gene_expression of Hif1a 8 0.50 11.14 2.68
56 INT109969 Positive_regulation of Phosphorylation of Trp53 1 0.45 2.18 2.66
57 INT24902 Gene_expression of SP1 17 0.71 8.11 2.58
58 INT188344 Positive_regulation of Gene_expression of Foxp3 10 0.36 5.97 2.56
59 INT23998 Positive_regulation of Sp1 4 0.40 0.51 2.56
60 INT109968 Positive_regulation of Positive_regulation of Trp53 6 0.47 3.57 2.51
61 INT96640 Negative_regulation of Gene_expression of Egr1 13 0.43 7.22 2.48
62 INT126581 Positive_regulation of Gli3 6 0.35 1.59 2.48
63 INT98634 Positive_regulation of Positive_regulation of EGR1 9 0.68 3.43 2.47
64 INT103609 Transcription of Sp1 1 0.11 0.97 2.42
65 INT74262 Negative_regulation of Egr1 15 0.57 7.51 2.41
66 INT55952 Transcription of TP53 16 0.61 12.14 2.36
67 INT100381 Positive_regulation of Positive_regulation of HIF1A 12 0.49 12.05 2.17
68 INT112364 Negative_regulation of HIF1A 22 0.57 16.95 2.13
69 INT15243 Regulation of Egr1 19 0.61 7.6 2.13
70 INT103608 Negative_regulation of Binding of Sp1 4 0.35 0.69 2.1
71 INT80599 Regulation of Positive_regulation of Egr1 3 0.28 0.46 2.09
72 INT41495 Regulation of Sp1 7 0.42 2.96 2.05
73 INT41557 Gene_expression of Sp1 5 0.68 1.17 2.04
74 INT126374 Gene_expression of Gli3 6 0.77 3.67 2.02
75 INT125080 Positive_regulation of Positive_regulation of TP53 21 0.58 16.16 1.98
76 INT221431 Negative_regulation of FOXP3 8 0.40 9.92 1.98
77 INT146793 Positive_regulation of Tp53 30 0.70 32.93 1.94
78 INT65855 Localization of TP53 18 0.76 17.08 1.89
79 INT73023 Binding of EGR1 7 0.48 4.23 1.86
80 INT38421 Positive_regulation of Zbtb7a 2 0.50 1.52 1.86
81 INT180134 Gene_expression of SIRT2 70 0.11 6.95 1.84
82 INT113345 Positive_regulation of Phosphorylation of TP53 8 0.66 6.11 1.8
83 INT57375 Regulation of EGR1 5 0.40 1.94 1.78
84 INT24906 Negative_regulation of SP1 8 0.40 4.48 1.77
85 INT116114 Phosphorylation of EID1 8 0.12 3.99 1.75
86 INT57875 Positive_regulation of Positive_regulation of Egr1 6 0.49 2.74 1.75
87 INT221426 Positive_regulation of Gene_expression of FOXP3 9 0.48 5.98 1.72
88 INT200223 Positive_regulation of EPAS1 21 0.17 21.95 1.7
89 INT122597 Transcription of Hif1a 5 0.69 5.56 1.63
90 INT127607 Gene_expression of EID1 4 0.63 5.57 1.6
91 INT153723 Negative_regulation of Gene_expression of Hif1a 2 0.41 1.25 1.58
92 INT41605 Positive_regulation of Localization of Sp1 1 0.05 0 1.58
93 INT57877 Negative_regulation of Positive_regulation of Egr1 4 0.42 1.63 1.57
94 INT64233 Regulation of Trp53 35 0.62 27.11 1.53
95 INT135171 Positive_regulation of Gene_expression of Hif1a 15 0.68 16.95 1.51
96 INT119048 Negative_regulation of Gene_expression of HIF1A 10 0.57 9.23 1.5
97 INT143443 Localization of HIF1A 14 0.78 10.93 1.49
98 INT120004 Transcription of Tp53 8 0.72 4.92 1.48
99 INT167872 Negative_regulation of Gene_expression of Foxp3 8 0.50 4.14 1.46
100 INT140245 Binding of Gli3 3 0.36 2.65 1.46
101 INT53003 Positive_regulation of Positive_regulation of Egr1 6 0.64 2.36 1.44
102 INT101990 Negative_regulation of Positive_regulation of TP53 5 0.33 3.69 1.42
103 INT162469 Positive_regulation of Protein_catabolism of TP53 5 0.52 5.48 1.42
104 INT98635 Negative_regulation of Gene_expression of EGR1 5 0.58 2.2 1.42
105 INT172953 Binding of Trp53 33 0.37 20.76 1.41
106 INT93357 Regulation of Gene_expression of Trp53 15 0.62 13.4 1.41
107 INT162462 Protein_catabolism of TP53 8 0.86 7.89 1.41
108 INT123414 Transcription of Sp1 5 0.48 2.2 1.38
109 INT145221 Binding of Tp53 10 0.37 8.59 1.37
110 INT141344 Transcription of Egr1 11 0.70 5.59 1.34
111 INT232785 Localization of Hif1a 8 0.46 10.37 1.33
112 INT116112 Negative_regulation of Phosphorylation of EID1 4 0.05 2.65 1.3
113 INT94692 Positive_regulation of Gene_expression of Sp1 3 0.17 0.39 1.28
114 INT24000 Regulation of Sp1 2 0.22 1.25 1.27
115 INT216380 Gene_expression of PAX6 49 0.78 15.63 1.22
116 INT48554 Positive_regulation of SP1 12 0.49 3.64 1.2
117 INT174156 Localization of Trp53 16 0.72 13.52 1.18
118 INT116436 Negative_regulation of Phosphorylation of TP53 2 0.40 0.94 1.16
119 INT229562 Negative_regulation of Foxp3 6 0.36 3.7 1.14
120 INT134661 Negative_regulation of Tp53 11 0.43 10.91 1.13
121 INT93216 Negative_regulation of Phosphorylation of Sp1 2 0.14 0.4 1.13
122 INT98633 Negative_regulation of Transcription of EGR1 3 0.43 0.79 1.11
123 INT102249 Binding of HIF1A 39 0.36 30.47 1.04
124 INT123503 Positive_regulation of Binding of Egr1 3 0.13 2.34 1.04
125 INT97052 Transcription of Trp53 12 0.64 6.52 1.01
126 INT123501 Negative_regulation of Binding of Egr1 2 0.12 2.04 0.99
127 INT51947 Regulation of Transcription of Egr1 2 0.59 0.15 0.96
128 INT123408 Positive_regulation of Gene_expression of Sp1 2 0.62 0.9 0.96
129 INT44375 Negative_regulation of ZBTB7A 3 0.57 0.95 0.95
130 INT123407 Negative_regulation of Binding of Sp1 6 0.47 0.72 0.93
131 INT200272 Localization of Sp1 3 0.57 0.06 0.93
132 INT98638 Positive_regulation of Transcription of EGR1 3 0.49 2.83 0.91
133 INT180136 Localization of SIRT2 15 0.12 1.42 0.88
134 INT221427 Positive_regulation of FOXP3 6 0.45 2.74 0.83
135 INT155352 Phosphorylation of HIF1A 3 0.79 3.34 0.83
136 INT123410 Negative_regulation of Gene_expression of Sp1 3 0.38 1.01 0.82
137 INT157492 Transcription of Foxp3 4 0.61 1.69 0.81
138 INT93356 Negative_regulation of Gene_expression of Trp53 28 0.53 20.61 0.8
139 INT100378 Protein_catabolism of HIF1A 7 0.96 5.05 0.8
140 INT135169 Binding of Hif1a 22 0.47 12.48 0.79
141 INT150251 Transcription of FOXP3 7 0.61 0.43 0.76
142 INT102813 Regulation of Gene_expression of TP53 25 0.59 25.95 0.75
143 INT168245 Positive_regulation of Transcription of Tp53 2 0.70 2.63 0.75
144 INT50968 Regulation of Zbtb7a 1 0.38 0.51 0.74
145 INT162470 Negative_regulation of Protein_catabolism of TP53 1 0.32 1.24 0.74
146 INT98636 Negative_regulation of Positive_regulation of EGR1 3 0.58 2.21 0.73
147 INT169731 Negative_regulation of Localization of HIF1A 1 0.57 0.57 0.73
148 INT183672 Gene_expression of EPAS1 37 0.35 28.68 0.72
149 INT180139 Protein_catabolism of SIRT2 11 0.14 1.1 0.72
150 INT100380 Negative_regulation of Positive_regulation of HIF1A 2 0.57 1.6 0.72
151 INT6050 Localization of Egr1 4 0.68 0.53 0.7
152 INT221428 Negative_regulation of Negative_regulation of FOXP3 1 0.35 1.97 0.7
153 INT68560 Regulation of Gli3 3 0.18 1.51 0.68
154 INT141341 Binding of Egr1 5 0.48 2.65 0.67
155 INT128795 Regulation of Positive_regulation of HIF1A 2 0.61 0.95 0.67
156 INT98967 Localization of SP1 2 0.60 0.15 0.66
157 INT233837 Negative_regulation of Hif1a 9 0.26 12.72 0.65
158 INT24905 Negative_regulation of Gene_expression of SP1 4 0.39 2.05 0.65
159 INT112708 Negative_regulation of Hif1a 5 0.38 2.7 0.64
160 INT102686 Phosphorylation of Egr1 3 0.59 2.57 0.64
161 INT100382 Positive_regulation of Protein_catabolism of HIF1A 2 0.45 1.75 0.64
162 INT297286 Positive_regulation of Foxp3 7 0.58 3.05 0.63
163 INT100377 Negative_regulation of Protein_catabolism of HIF1A 1 0.57 0.9 0.63
164 INT136465 Regulation of Hif1a 5 0.39 7.05 0.62
165 INT112363 Regulation of Gene_expression of HIF1A 6 0.60 2.28 0.61
166 INT155353 Positive_regulation of Phosphorylation of HIF1A 1 0.49 2.58 0.61
167 INT93358 Negative_regulation of Positive_regulation of Trp53 9 0.41 3.95 0.6
168 INT53950 Phosphorylation of Tp53 8 0.61 9.4 0.6
169 INT126899 Regulation of SP1 5 0.43 2.53 0.57
170 INT73020 Positive_regulation of Binding of EGR1 1 0.49 0.46 0.56
171 INT98632 Negative_regulation of EGR1 6 0.42 3.38 0.54
172 INT192656 Negative_regulation of EID1 2 0.04 0.93 0.54
173 INT135173 Regulation of Gene_expression of Hif1a 3 0.44 2.49 0.53
174 INT134758 Positive_regulation of Transcription of Hif1a 2 0.33 2.44 0.53
175 INT81061 Regulation of Negative_regulation of Egr1 1 0.22 0 0.53
176 INT135062 Transcription of Gli3 1 0.05 0 0.52
177 INT153065 Regulation of Hif1a 8 0.28 8.57 0.51
178 INT89334 Negative_regulation of Binding of SP1 2 0.47 1.05 0.5
179 INT286035 Negative_regulation of Gene_expression of Tp53 5 0.32 6.2 0.49
180 INT168801 Localization of Egr1 4 0.78 0.7 0.48
181 INT44374 Localization of ZBTB7A 1 0.68 0 0.48
182 INT153067 Positive_regulation of Positive_regulation of Hif1a 10 0.49 11.83 0.47
183 INT157490 Regulation of Gene_expression of Foxp3 5 0.37 2.4 0.47
184 INT141342 Negative_regulation of Transcription of Egr1 4 0.43 2.39 0.45
185 INT144969 Binding of EPAS1 3 0.06 4.12 0.44
186 INT126896 Positive_regulation of Protein_catabolism of SP1 1 0.13 0.99 0.44
187 INT188345 Regulation of Foxp3 3 0.18 1.59 0.42
188 INT180142 Negative_regulation of SIRT2 10 0.07 0.19 0.41
189 INT180138 Negative_regulation of Gene_expression of SIRT2 2 0.07 0.19 0.41
190 INT45769 Positive_regulation of Negative_regulation of ZBTB7A 1 0.49 0 0.41
191 INT243756 Regulation of Positive_regulation of Egr1 7 0.45 1.18 0.4
192 INT139976 Regulation of Tp53 7 0.44 6.49 0.39
193 INT126895 Protein_catabolism of SP1 3 0.96 3.59 0.38
194 INT98963 Positive_regulation of Binding of SP1 1 0.43 0 0.37
195 INT247549 Transcription of Hif1a 7 0.42 8.77 0.36
196 INT145220 Negative_regulation of Binding of Tp53 1 0.20 0.75 0.36
197 INT166959 Positive_regulation of Positive_regulation of SP1 3 0.46 2.23 0.35
198 INT144968 Positive_regulation of Localization of EGR1 1 0.69 0.82 0.35
199 INT260115 Regulation of FOXP3 3 0.29 0.75 0.34
200 INT320784 Protein_catabolism of Hif1a 3 0.61 2.41 0.34
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