GO:0035051

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Name cardiac cell differentiation
Categary Process
Go Slim No
Go Link GO:0035051
Unique Molecular Interactions 54
Total Molecular Interactions 82
Total Single Events 666
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cardiac cell differentiation. They are ordered first by their pain relevance and then by number of times they were reported for cardiac cell differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT210783 Bmp2 Positive_regulation of Tnip1 1 0.40 0.53 0.94
2 INT210791 Bmp2 Positive_regulation of Net1 1 0.38 0.52 0.93
3 INT210799 Bmp2 Positive_regulation of B2m 1 0.35 0.52 0.92
4 INT210793 Bmp2 Positive_regulation of Tsc22d3 1 0.32 0.26 0.46
5 INT224687 Il1 Positive_regulation of Bmp2 1 0.00 0.3 0.31
6 INT166165 Binding of TGFB3 and Bmp2 1 0.00 0 0.3
7 INT182817 EEF1A2 Positive_regulation of BMP2 1 0.26 1.62 0.28
8 INT350723 MIR219-1 Negative_regulation of Sox6 1 0.01 0.4 0.15
9 INT326974 BMP2 Positive_regulation of Gene_expression of COL2A1 1 0.07 0.27 0.11
10 INT238038 Binding of BMP2 and OPLL 1 0.20 2.45 0.09
11 INT238628 Mef2c Regulation of Gene_expression of Arc 1 0.09 0.16 0.08
12 INT238625 Mef2c Regulation of Gene_expression of Syngap1 1 0.10 0.16 0.08
13 INT297968 Positive_regulation of Binding of BMP2 and IL17C 1 0.21 0.26 0.08
14 INT297970 Binding of BMP2 and IL17C 1 0.15 0.26 0.08
15 INT295122 Bmp2 Regulation of Grxcr1 1 0.02 0.66 0.06
16 INT295120 Bmp2 Regulation of Transcription of Pou1f1 1 0.24 0.66 0.06
17 INT173613 BMP2 Positive_regulation of INCENP 1 0.00 0.28 0.03
18 INT324836 Nox4 Regulation of Gene_expression of ROS1 1 0.01 0.13 0.03
19 INT287233 PDLIM7 Positive_regulation of Gene_expression of BMP2 1 0.07 0.12 0.03
20 INT290437 Gene_expression of Mef2c Negative_regulation of Upf1 1 0.02 0.25 0.03
21 INT184209 IL1B Negative_regulation of Gene_expression of SOX6 1 0.46 0.05 0.03
22 INT324800 Binding of Tlr4 and Nox4 1 0.12 0.14 0.03
23 INT343999 INCENP Positive_regulation of BMP2 1 0.01 0 0
24 INT278021 BMP2 Positive_regulation of Gene_expression of RUNX1T1 1 0.02 0.5 0
25 INT205451 Binding of BMP2 and Acvr2a 1 0.02 0.05 0
26 INT350706 Binding of Mef2c and Mir223 1 0.02 0.11 0
27 INT290439 Negative_regulation of Mef2c Positive_regulation of Gene_expression of Ppargc1a 1 0.21 0 0
28 INT290441 Mef2c Regulation of Mef2b 1 0.09 0.11 0
29 INT196023 Bmp2 Negative_regulation of Gene_expression of Bmp4 1 0.09 0.07 0
30 INT205410 Binding of BMP2 and BMPR2 1 0.07 0.05 0
31 INT297213 Myoz1 Regulation of Mef2c 1 0.02 0.09 0
32 INT290438 Mef2c Regulation of Mef2a 1 0.26 0.11 0
33 INT344001 INCENP Positive_regulation of Gene_expression of BMP2 1 0.01 0 0
34 INT196021 Bmp2 Positive_regulation of Gene_expression of Bmp4 1 0.09 0.08 0
35 INT269062 Nox4 Negative_regulation of Localization of Cyba 1 0.17 0 0
36 INT295129 Proc Regulation of Bmp2 1 0.00 0.48 0
37 INT321594 Bmp2 Regulation of Gene_expression of Lxn 1 0.42 1.71 0
38 INT269067 Nox4 Negative_regulation of Localization of Ncf1 1 0.17 0 0
39 INT277611 Binding of Mef2c and Hdac4 1 0.34 1.12 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for cardiac cell differentiation. They are ordered first by their pain relevance and then by number of times they were reported in cardiac cell differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT85809 Gene_expression of BMP2 46 0.78 9.91 3.05
2 INT96423 Gene_expression of Bmp2 61 0.78 25.07 3.01
3 INT130014 Positive_regulation of BMP2 11 0.66 5.34 1.42
4 INT70619 Regulation of Bmp2 6 0.60 3.1 1.29
5 INT96424 Transcription of Bmp2 6 0.69 6.34 1.11
6 INT160538 Binding of Bmp2 4 0.40 2.08 1.07
7 INT114664 Binding of BMP2 12 0.37 6.54 0.91
8 INT277586 Negative_regulation of Mef2c 36 0.59 11.03 0.86
9 INT202361 Gene_expression of Mef2c 28 0.78 5.53 0.67
10 INT238049 Positive_regulation of Gene_expression of BMP2 8 0.51 2.06 0.59
11 INT85808 Localization of BMP2 7 0.77 1.94 0.51
12 INT145301 Regulation of Gene_expression of Bmp2 1 0.32 1.16 0.48
13 INT120086 Gene_expression of Bmp2 5 0.27 2.34 0.43
14 INT199078 Gene_expression of Nox4 3 0.59 3.83 0.41
15 INT84945 Transcription of BMP2 5 0.61 1.8 0.36
16 INT196026 Positive_regulation of Gene_expression of Bmp2 14 0.69 3.19 0.35
17 INT238560 Regulation of Mef2c 9 0.45 2.12 0.33
18 INT145305 Positive_regulation of Bmp2 12 0.69 8.65 0.24
19 INT109699 Regulation of BMP2 5 0.43 2.21 0.23
20 INT202355 Transcription of Mef2c 3 0.69 0.6 0.21
21 INT248543 Positive_regulation of Mef2c 7 0.69 2.82 0.18
22 INT148064 Localization of Bmp2 2 0.29 0.14 0.17
23 INT277602 Binding of Mef2c 10 0.39 4.35 0.16
24 INT106010 Positive_regulation of Bmp2 2 0.26 0.91 0.15
25 INT254335 Gene_expression of Sox6 2 0.43 0.25 0.12
26 INT254992 Negative_regulation of Gene_expression of BMP2 3 0.34 0.56 0.11
27 INT238044 Positive_regulation of Transcription of BMP2 2 0.43 0.83 0.11
28 INT326976 Regulation of Localization of BMP2 1 0.59 0.08 0.1
29 INT196035 Localization of Bmp2 3 0.63 0.23 0.09
30 INT278036 Negative_regulation of BMP2 2 0.34 0.64 0.09
31 INT114663 Regulation of Binding of BMP2 1 0.38 0.19 0.09
32 INT163072 Regulation of Binding of Bmp2 1 0.30 0.52 0.08
33 INT290404 Positive_regulation of Negative_regulation of Mef2c 1 0.50 0.72 0.08
34 INT277578 Regulation of Negative_regulation of Mef2c 2 0.45 1.17 0.07
35 INT290417 Positive_regulation of Gene_expression of Mef2c 1 0.50 1.25 0.06
36 INT196025 Negative_regulation of Bmp2 2 0.34 0.14 0.05
37 INT229753 Positive_regulation of Gene_expression of Bmp2 2 0.11 1.22 0.04
38 INT287236 Positive_regulation of Positive_regulation of BMP2 1 0.29 0.08 0.04
39 INT290407 Positive_regulation of Binding of Mef2c 1 0.44 0.93 0.04
40 INT184219 Gene_expression of SOX6 4 0.59 0.13 0.03
41 INT290419 Regulation of Gene_expression of Mef2c 1 0.62 0.41 0.03
42 INT290399 Negative_regulation of Gene_expression of Mef2c 1 0.59 0.59 0.03
43 INT189593 Regulation of Gene_expression of BMP2 2 0.33 0.8 0
44 INT145300 Positive_regulation of Positive_regulation of Bmp2 2 0.34 1.03 0
45 INT269895 Binding of Sox6 2 0.27 0.33 0
46 INT196031 Binding of Bmp2 1 0.16 0 0
47 INT278735 Negative_regulation of Gene_expression of Bmp2 1 0.43 0.06 0
48 INT290400 Regulation of Regulation of Mef2c 1 0.45 0.24 0
49 INT184226 Regulation of Negative_regulation of SOX6 1 0.34 0 0
50 INT290429 Negative_regulation of Negative_regulation of Mef2c 1 0.37 0.05 0
51 INT251809 Localization of SOX6 1 0.45 0 0
52 INT278737 Positive_regulation of Transcription of Bmp2 1 0.47 1.4 0
53 INT120087 Negative_regulation of Gene_expression of Bmp2 1 0.11 0.14 0
54 INT184225 Regulation of Gene_expression of SOX6 1 0.47 0 0
55 INT290425 Negative_regulation of Binding of Mef2c 1 0.37 0 0
56 INT290409 Negative_regulation of Transcription of Mef2c 1 0.43 0.08 0
57 INT184224 Negative_regulation of Gene_expression of SOX6 1 0.44 0 0
58 INT278040 Negative_regulation of Localization of BMP2 1 0.32 0.32 0
59 INT352006 Negative_regulation of Sox6 1 0.31 0.08 0
60 INT184221 Negative_regulation of SOX6 1 0.32 0 0
61 INT277587 Localization of Mef2c 1 0.65 0.43 0
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