GO:0035094

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Name response to nicotine
Categary Process
Go Slim No
Go Link GO:0035094
Unique Molecular Interactions 1800
Total Molecular Interactions 2600
Total Single Events 28848
Pain Genes Associated 48

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for response to nicotine. They are ordered first by their pain relevance and then by number of times they were reported for response to nicotine. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT69886 Ngf Positive_regulation of Calca 8 0.76 2.98 12.77
2 INT145775 Ngf Positive_regulation of Trpv1 11 0.72 7.71 11.25
3 INT77646 Binding of Ngf and Ntrk1 23 0.40 7.85 9.26
4 INT69229 Ngf Positive_regulation of Gene_expression of Bdnf 6 0.76 8.19 6.66
5 INT140015 Avp Positive_regulation of Localization of Penk 3 0.63 3.48 6.63
6 INT84921 Binding of NGF and NTRK1 13 0.50 6.39 6.1
7 INT122779 Ngf Positive_regulation of Gene_expression of Trpv1 8 0.74 4.31 6.1
8 INT88279 Ngf Positive_regulation of Ntrk1 5 0.76 3.06 5.23
9 INT69888 Ngf Positive_regulation of Localization of Calca 4 0.52 0.51 4.95
10 INT38217 Penk Regulation of Localization of Avp 2 0.38 0.56 4.45
11 INT240653 Ngf Positive_regulation of Positive_regulation of Bdnf 1 0.55 2.97 4.23
12 INT161109 Avp Positive_regulation of Chkb 1 0.12 0.18 4.19
13 INT143270 Binding of Cnr1 and Gprasp1 4 0.54 0.64 4.18
14 INT127128 Binding of CNR1 and CNR2 8 0.39 3.98 3.97
15 INT82023 Binding of Ntrk1 and Ngf 5 0.53 3.48 3.92
16 INT122349 Ngf Regulation of Trpv1 3 0.64 1.55 3.79
17 INT180813 Ngf Positive_regulation of Sorbs1 1 0.04 2.09 3.79
18 INT69938 Cck Positive_regulation of Localization of Abat 2 0.29 0 3.78
19 INT141254 Ngf Regulation of Transcription of Trpv1 1 0.53 1.37 3.74
20 INT85541 Ngf Positive_regulation of Gene_expression of Calca 2 0.55 1.84 3.71
21 INT132862 Ngf Positive_regulation of Bdnf 4 0.46 4.05 3.65
22 INT15984 Binding of Avp and Oxt 11 0.32 1.33 3.64
23 INT140011 Avp Positive_regulation of Dbi 2 0.07 0.93 3.61
24 INT74159 Ngf Regulation of Gene_expression of Calca 2 0.60 1.66 3.22
25 INT270949 Binding of Slc6a3 and Cpe 1 0.28 0.25 3.19
26 INT122780 Ngf Regulation of Gene_expression of Trpv1 4 0.65 3.74 3.11
27 INT106338 Positive_regulation of Tacr1 Positive_regulation of Localization of Abat 5 0.34 0 3.01
28 INT113234 Binding of Pax3 and Tacr1 3 0.12 1.54 2.93
29 INT264929 Binding of Cnr1 and Gnaz 1 0.18 1.71 2.89
30 INT69937 Cck Positive_regulation of Abat 2 0.31 0 2.88
31 INT221746 Ngf Positive_regulation of Ntrk1 1 0.02 0.92 2.88
32 INT140014 Avp Negative_regulation of Chkb 1 0.04 1.58 2.86
33 INT220062 Binding of NGF and TNFRSF1B 1 0.10 2.21 2.81
34 INT147107 TGFB1 Positive_regulation of Gene_expression of NGF 1 0.49 0.67 2.69
35 INT124547 Trib3 Regulation of Regulation of Th 1 0.02 0.79 2.64
36 INT326585 Binding of GYPA and SLC6A3 1 0.13 0.86 2.64
37 INT7888 Oprl1 Regulation of Localization of Avp 4 0.49 0.25 2.63
38 INT152113 Binding of NTSR1 and Ngf 3 0.33 2.09 2.62
39 INT104219 SCD Positive_regulation of Cnr1 1 0.00 2.67 2.54
40 INT143271 Binding of Gprasp1 and Positive_regulation of Negative_regulation of Cnr1 1 0.78 0.16 2.53
41 INT170037 Ngf Regulation of Gene_expression of DRGX 1 0.01 1.37 2.46
42 INT103330 Ngf Positive_regulation of Gdnf 2 0.28 1.27 2.45
43 INT143272 Binding of CNR1 and Gprasp1 1 0.01 0.17 2.42
44 INT103332 Ngf Regulation of Gene_expression of TRPV1 3 0.09 2.6 2.4
45 INT106750 Pes1 Negative_regulation of Positive_regulation of Casp3 3 0.23 0 2.35
46 INT238914 Positive_regulation of CNR1 Positive_regulation of Phosphorylation of MAPK1 1 0.19 3.22 2.35
47 INT121726 Ngf Positive_regulation of Phosphorylation of Akt1 1 0.37 1.4 2.34
48 INT108987 Ngf Regulation of Gene_expression of Sit1 1 0.00 1.46 2.32
49 INT85252 Negative_regulation of Chi3l1 Positive_regulation of Casp3 1 0.01 0 2.26
50 INT85251 Chi3l1 Positive_regulation of Casp3 1 0.01 0 2.25
51 INT198958 Cnr1 Positive_regulation of Kcnj9 1 0.00 0.15 2.24
52 INT106753 Pes1 Negative_regulation of Gene_expression of Casp3 2 0.12 0 2.19
53 INT69887 Ngf Regulation of Calca 2 0.49 0.1 2.19
54 INT113451 Ngf Regulation of Gene_expression of ASIC3 1 0.07 1.35 2.18
55 INT12140 Ngf Regulation of Chat 1 0.44 1.67 2.18
56 INT66803 Oxt Regulation of Avp 7 0.16 0.19 2.15
57 INT212301 NGF Regulation of Gene_expression of TRPV1 1 0.23 2.37 2.13
58 INT140019 Avp Positive_regulation of Localization of Kitl 1 0.00 1 2.13
59 INT120319 Ghrh Regulation of Ngf 1 0.25 1.89 2.11
60 INT113452 Ngf Positive_regulation of Gene_expression of ASIC3 1 0.19 1.34 2.08
61 INT117821 Binding of Tacr1 and Cd4 1 0.34 0.86 2.02
62 INT245348 Binding of Abat and Vta1 1 0.03 0.53 2.01
63 INT138960 Dbi Positive_regulation of Avp 1 0.02 1.53 2
64 INT138958 Dbi Positive_regulation of Positive_regulation of Avp 1 0.02 1.53 2
65 INT274372 Phc1 Negative_regulation of Slc6a3 1 0.06 0.47 1.99
66 INT45423 Avp Positive_regulation of Localization of Prl 4 0.67 1.37 1.98
67 INT34662 Abat Positive_regulation of Localization of Gnrh1 1 0.26 0 1.98
68 INT58678 Binding of Penk and Abat 2 0.40 1.39 1.97
69 INT13430 Abat Positive_regulation of Localization of Sst 2 0.33 0 1.94
70 INT146587 Npff Negative_regulation of Positive_regulation of Casp3 1 0.05 0.18 1.92
71 INT146586 Npff Negative_regulation of Gene_expression of Casp3 1 0.06 0.18 1.92
72 INT264928 Binding of Cnr1 and Hrh1 1 0.01 1.61 1.92
73 INT83418 Binding of OPRL1 and Ntrk1 1 0.02 0 1.91
74 INT91607 Binding of EDN1 and POMC 1 0.12 0 1.9
75 INT271408 NGF Positive_regulation of Gene_expression of CALCA 1 0.09 4.89 1.88
76 INT205152 Binding of CD44 and MMP9 23 0.35 17.13 1.85
77 INT276668 Ngf Regulation of Nav1 1 0.09 0.98 1.85
78 INT185097 NGF Regulation of Gene_expression of NAV1 1 0.61 0.81 1.85
79 INT40239 Penk Regulation of Avp 1 0.07 0 1.84
80 INT117269 Binding of Avp and Prl 1 0.25 0.47 1.8
81 INT145940 Binding of Gad1 and Abat 2 0.14 1.44 1.78
82 INT136273 NGF Regulation of Gene_expression of BDNF 2 0.41 1.14 1.78
83 INT336556 SLC6A3 Positive_regulation of Gene_expression of GOPC 1 0.08 1.87 1.76
84 INT102160 Binding of Mmp2 and Mmp9 3 0.28 2.87 1.75
85 INT86997 Binding of HIVEP1 and NGF 2 0.03 1.75 1.73
86 INT264922 Binding of Cnr1 and Mors1 1 0.14 0.1 1.71
87 INT10202 Agt Positive_regulation of Avp 3 0.70 0 1.69
88 INT80199 Ngf Regulation of Transcription of Rab38 1 0.01 1.48 1.68
89 INT145098 NGF Positive_regulation of BDNF 1 0.66 1.33 1.67
90 INT108385 Binding of Crygs and Ntrk1 1 0.01 0 1.67
91 INT108066 Binding of NTRK1 and Ngf 3 0.33 2.56 1.66
92 INT23889 Calca Positive_regulation of Localization of Tacr1 1 0.11 0.45 1.65
93 INT90658 Abat Regulation of Localization of Cck 2 0.24 0 1.64
94 INT140009 Avp Positive_regulation of Gene_expression of Penk 1 0.40 0.77 1.64
95 INT140023 Avp Positive_regulation of Gene_expression of Kitl 1 0.00 0.76 1.62
96 INT63939 Vta1 Positive_regulation of Th 1 0.14 0 1.61
97 INT266768 NGF Positive_regulation of Localization of SFTPA1 1 0.01 1.65 1.6
98 INT140341 Ngf Positive_regulation of Gene_expression of Oprm1 1 0.02 0.33 1.59
99 INT136034 Edn1 Regulation of Trpv1 2 0.66 0.39 1.58
100 INT94271 Pomc Regulation of Avp 1 0.20 0.67 1.57
101 INT315284 PRKG1 Positive_regulation of Nos1 1 0.33 0.85 1.56
102 INT106751 Pes1 Negative_regulation of Casp3 2 0.23 0 1.54
103 INT170654 Binding of Ntf3 and Ngf 1 0.38 1.66 1.54
104 INT40887 Penk Regulation of Th 1 0.04 0 1.53
105 INT140013 Avp Positive_regulation of Gene_expression of Dbi 1 0.07 0.85 1.52
106 INT140016 Avp Positive_regulation of Gene_expression of Pdyn 1 0.21 0.85 1.52
107 INT140017 Avp Positive_regulation of Gene_expression of Pomc 1 0.38 0.85 1.52
108 INT137657 Gorasp2 Regulation of Binding of Casp3 1 0.09 0 1.52
109 INT192081 Igkv11-125 Positive_regulation of Cnr1 1 0.10 0.23 1.51
110 INT140008 Avp Positive_regulation of Pomc 1 0.38 0.84 1.51
111 INT159657 Binding of INSRR and NGF 3 0.00 1.65 1.48
112 INT220058 NGF Positive_regulation of Gene_expression of BDNF 1 0.12 1.31 1.48
113 INT220059 NGF Positive_regulation of Positive_regulation of BDNF 1 0.11 1.31 1.48
114 INT59547 Avp Positive_regulation of Crh 2 0.14 1.13 1.47
115 INT156008 Bcl2 Regulation of Localization of Aifm1 1 0.17 1.92 1.47
116 INT116094 Binding of TACR1 and TFF2 1 0.06 0 1.47
117 INT83416 Binding of OPRK1 and Ntrk1 1 0.02 0 1.45
118 INT45307 ENG Positive_regulation of Localization of Avp 1 0.00 0 1.45
119 INT180789 Ngf Regulation of Localization of Trpv1 1 0.28 1.22 1.44
120 INT140012 Avp Negative_regulation of Dbi 1 0.06 0.8 1.44
121 INT5534 Binding of Oxt and Avp 7 0.04 0.6 1.43
122 INT30872 Abat Positive_regulation of Localization of Gast 1 0.26 0 1.43
123 INT266771 Binding of NGF and GOPC 1 0.05 3.23 1.43
124 INT150069 Cnr1 Regulation of Cnr2 2 0.50 0.83 1.42
125 INT10548 Nts Regulation of Localization of Abat 2 0.14 0 1.42
126 INT202910 Uchl1 Positive_regulation of Gene_expression of Tacr1 1 0.05 1.65 1.42
127 INT329451 Binding of Oprd1 and Tacr1 1 0.05 0.23 1.41
128 INT100908 Slc6a3 Regulation of Positive_regulation of Etf1 1 0.05 0 1.41
129 INT180809 Ngf Positive_regulation of Positive_regulation of Sorbs1 1 0.03 0.84 1.4
130 INT142490 Avp Regulation of Oxt 1 0.09 0.74 1.4
131 INT180808 Ngf Positive_regulation of Gene_expression of Sorbs1 1 0.03 0.84 1.4
132 INT220060 Negative_regulation of Binding of NGF and NTRK1 1 0.08 1.11 1.39
133 INT118980 NTRK1 Positive_regulation of NGF 1 0.56 1.45 1.39
134 INT51160 Binding of TAC1 and Tacr1 2 0.28 0.55 1.38
135 INT140021 Avp Positive_regulation of Pag1 1 0.03 0.85 1.38
136 INT140018 Avp Positive_regulation of Gene_expression of Pag1 1 0.04 0.85 1.38
137 INT140020 Avp Positive_regulation of Localization of Pag1 1 0.03 0.85 1.38
138 INT82025 Negative_regulation of Binding of Ntrk1 and Ngf 1 0.47 0.64 1.37
139 INT83197 Binding of Ntrk1 and Gdnf 1 0.01 1.05 1.36
140 INT60992 Ngf Regulation of CRTAC1 1 0.00 0 1.35
141 INT151770 Binding of P2RX3 and Ngf 1 0.18 0.9 1.35
142 INT250934 Binding of BDNF and NGF 3 0.39 0.62 1.34
143 INT145930 ecs Positive_regulation of Gene_expression of Bcl2 1 0.01 2.06 1.34
144 INT140531 Ngf Positive_regulation of DYT10 1 0.72 1.83 1.34
145 INT60989 Ngf Regulation of Th 1 0.17 0 1.34
146 INT178986 Binding of MMP9 and TIMP1 4 0.47 2.58 1.33
147 INT180786 Calca Regulation of Positive_regulation of Ngf 1 0.40 0 1.32
148 INT355252 Binding of Cacna1a and Cnr1 1 0.04 0 1.31
149 INT181492 NGF Regulation of TRPV1 1 0.21 0.93 1.31
150 INT132412 Negative_regulation of Ngf Negative_regulation of Ptgs1 1 0.01 0.81 1.31
151 INT198957 Binding of Cnr1 and Mastl 1 0.00 0 1.31
152 INT192080 Foxm1 Positive_regulation of Cnr1 2 0.14 0.72 1.3
153 INT95275 Binding of Edn1 and Ece1 1 0.32 2.09 1.3
154 INT95274 Regulation of Binding of Edn1 and Ece1 1 0.39 2.09 1.3
155 INT95457 Nka1 Positive_regulation of Tacr1 1 0.63 0.29 1.3
156 INT147653 TACR1 Positive_regulation of TRPV1 1 0.02 0.72 1.29
157 INT48881 TWIST1 Positive_regulation of Localization of Abat 1 0.02 0.44 1.29
158 INT7284 Abat Regulation of Sst 1 0.18 0 1.28
159 INT83707 Acyp2-ps1 Regulation of Casp3 1 0.17 0 1.28
160 INT83705 Acyp2-ps1 Regulation of Positive_regulation of Casp3 1 0.17 0 1.28
161 INT112961 NGF Positive_regulation of ICAM1 1 0.40 0.96 1.28
162 INT169289 CNR1 Positive_regulation of EGFR 1 0.62 0.36 1.28
163 INT98833 Th Regulation of Gene_expression of Drd2 1 0.19 0.64 1.27
164 INT86090 SCN5A Negative_regulation of Positive_regulation of Abat 1 0.00 0 1.25
165 INT202042 CAMK2N2 Negative_regulation of MMP9 1 0.01 0.73 1.25
166 INT145315 D2Mit212 Regulation of Casp3 1 0.00 0 1.24
167 INT145316 D2Mit212 Regulation of Positive_regulation of Casp3 1 0.00 0 1.24
168 INT145317 D2Mit212 Positive_regulation of Casp3 1 0.01 0 1.22
169 INT121729 Negative_regulation of Ngf Positive_regulation of Ephb1 1 0.24 0.69 1.22
170 INT52955 Binding of Slc6a3 and Pdpn 1 0.17 1.11 1.22
171 INT62596 Binding of Edn1 and Nppa 1 0.27 1.77 1.22
172 INT121724 Ngf Positive_regulation of Ephb1 1 0.40 0.68 1.21
173 INT210982 Binding of Cnr1 and Cfp 2 0.22 1.27 1.2
174 INT98832 Th Regulation of Dbh 1 0.32 0.53 1.2
175 INT108065 Negative_regulation of Binding of Ngf and IgG-2a 1 0.01 2.38 1.2
176 INT131462 NGF Regulation of Localization of INS 1 0.40 0.97 1.2
177 INT187172 RPS3AP9 Negative_regulation of MMP9 1 0.00 0.89 1.2
178 INT63384 Binding of Cnr1 and Insrr 1 0.03 0.24 1.2
179 INT108067 Negative_regulation of Binding of NTRK1 and Ngf 1 0.06 2.38 1.2
180 INT81097 Akr1d1 Regulation of Localization of Abat 1 0.00 0 1.2
181 INT108469 Tacr1 Regulation of Transcription of Drd2 1 0.07 0.14 1.2
182 INT108064 Binding of Ngf and IgG-2a 1 0.01 2.36 1.19
183 INT140010 Avp Regulation of Gene_expression of Penk 1 0.25 0.58 1.19
184 INT201067 Binding of Edn1 and Ednra 2 0.18 1.36 1.18
185 INT75126 Pnoc Regulation of Localization of Avp 2 0.26 0.24 1.18
186 INT27621 Avp Positive_regulation of Protein_catabolism of Mbis1 1 0.00 0 1.18
187 INT351373 Ngf Positive_regulation of Gene_expression of Ntrk1 1 0.35 0.41 1.18
188 INT122370 Positive_regulation of Tacr1 Positive_regulation of Ngf 1 0.30 0.17 1.18
189 INT170655 Binding of Csf2 and Ngf 1 0.36 1.25 1.18
190 INT93435 Binding of Casp3 and Cckbr 1 0.06 0.15 1.18
191 INT351378 Gene_expression of Ngf Positive_regulation of Ntrk1 1 0.35 0.41 1.18
192 INT34661 Abat Positive_regulation of Localization of Pomc 1 0.04 0 1.18
193 INT351377 Gene_expression of Ngf Positive_regulation of Gene_expression of Ntrk1 1 0.35 0.41 1.18
194 INT148437 Binding of Bdnf and Ngf 2 0.32 1.9 1.17
195 INT141245 Prkaca Regulation of Gene_expression of Th 1 0.15 0.17 1.17
196 INT141246 Trib3 Regulation of Gene_expression of Th 1 0.02 0.17 1.17
197 INT140022 Avp Regulation of Localization of Pag1 1 0.01 0.57 1.17
198 INT60990 Bdnf Negative_regulation of Th 1 0.15 0 1.17
199 INT30871 Abat Regulation of Localization of Sst 1 0.13 0 1.17
200 INT238916 CNR1 Positive_regulation of Phosphorylation of MAPK1 1 0.19 1.61 1.17

Single Events

The table below shows the top 100 pain related interactions that have been reported for response to nicotine. They are ordered first by their pain relevance and then by number of times they were reported in response to nicotine. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT3439 Localization of Abat 1017 0.78 112.39 727.06
2 INT5680 Gene_expression of Ngf 530 0.78 264.29 310.56
3 INT477 Localization of Avp 813 0.81 131.58 300.4
4 INT2909 Positive_regulation of Abat 334 0.70 62.1 256.43
5 INT11377 Positive_regulation of Ngf 331 0.70 206.5 238
6 INT9987 Gene_expression of Abat 296 0.78 95.46 226.34
7 INT4893 Gene_expression of Tacr1 366 0.78 129.67 213.92
8 INT22548 Positive_regulation of Casp3 483 0.70 258.78 213.07
9 INT2211 Negative_regulation of Abat 267 0.59 66.51 200.98
10 INT3440 Negative_regulation of Localization of Abat 221 0.57 33.94 180.36
11 INT4740 Gene_expression of Th 298 0.78 61.27 154.03
12 INT2910 Regulation of Abat 169 0.62 36.95 153.53
13 INT4829 Positive_regulation of Localization of Abat 199 0.55 20.91 150.48
14 INT2451 Positive_regulation of Avp 355 0.70 102.66 147.69
15 INT1273 Gene_expression of Avp 356 0.78 90.56 138.7
16 INT4824 Positive_regulation of Tacr1 169 0.70 66.1 123.46
17 INT14151 Gene_expression of Casp3 311 0.78 140.26 120.68
18 INT218 Positive_regulation of Th 245 0.70 40.5 120.1
19 INT4207 Regulation of Avp 267 0.62 63.72 115.33
20 INT7327 Regulation of Th 164 0.62 29.67 110.14
21 INT65731 Gene_expression of Cnr1 234 0.78 63.82 109.34
22 INT4936 Localization of Tacr1 125 0.80 35.7 107.7
23 INT5940 Negative_regulation of Avp 236 0.59 67.86 101.2
24 INT74058 Gene_expression of Nos1 260 0.78 80.04 95.71
25 INT69764 Positive_regulation of Cnr1 126 0.70 67.8 91.49
26 INT214 Localization of AVP 370 0.81 208.51 91.09
27 INT74376 Gene_expression of Cnr1 173 0.78 73.43 89.7
28 INT3441 Regulation of Localization of Abat 117 0.38 8.67 87.59
29 INT4857 Regulation of Tacr1 115 0.62 39.01 84.52
30 INT16254 Positive_regulation of Gene_expression of Ngf 144 0.70 80.61 82.08
31 INT4358 Positive_regulation of Localization of Avp 195 0.70 30.79 77.58
32 INT17546 Negative_regulation of Ngf 135 0.59 60.28 77.19
33 INT62374 Gene_expression of NGF 158 0.78 77.87 76.45
34 INT12001 Regulation of Ngf 97 0.62 54.64 76.25
35 INT7886 Regulation of Localization of Avp 146 0.62 14.53 72.99
36 INT3034 Localization of Ngf 126 0.81 50.81 72.84
37 INT65733 Positive_regulation of Cnr1 125 0.70 40.27 67.33
38 INT2212 Binding of Abat 89 0.48 18.36 63.99
39 INT480 Negative_regulation of Localization of Avp 151 0.59 27.64 63.72
40 INT6894 Gene_expression of CNR1 168 0.78 74.07 62.84
41 INT217 Negative_regulation of Th 134 0.59 26.83 62.63
42 INT50971 Gene_expression of Ntrk1 180 0.75 73.52 62.28
43 INT18981 Gene_expression of ABAT 78 0.68 38.35 61.36
44 INT73048 Gene_expression of MMP9 268 0.77 159.75 57.81
45 INT5017 Negative_regulation of Tacr1 76 0.58 17 57.07
46 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03
47 INT37219 Gene_expression of TACR1 56 0.78 32.4 54.16
48 INT22546 Positive_regulation of Gene_expression of Casp3 97 0.70 47.89 51.92
49 INT50334 Negative_regulation of Cnr1 84 0.58 30.86 51.75
50 INT62630 Positive_regulation of CNR1 86 0.70 40.34 51.51
51 INT49028 Positive_regulation of Nos1 102 0.70 34.73 51.05
52 INT19488 Localization of ABAT 56 0.69 21.51 50.56
53 INT683 Positive_regulation of AVP 173 0.70 74.55 46.41
54 INT5781 Gene_expression of Edn1 190 0.78 99.1 46
55 INT49552 Negative_regulation of Positive_regulation of Casp3 76 0.55 36.04 44.78
56 INT27493 Negative_regulation of Casp3 114 0.56 56.89 44.63
57 INT63383 Binding of Cnr1 77 0.48 22.28 44.61
58 INT19078 Binding of Ngf 78 0.48 31.03 44.33
59 INT100939 Gene_expression of Il13 176 0.73 125.1 43.38
60 INT350 Localization of Th 79 0.80 10.26 41.17
61 INT12228 Positive_regulation of Gene_expression of Abat 44 0.65 17.51 40.55
62 INT685 Regulation of AVP 124 0.62 34.9 39.91
63 INT16194 Binding of CNR1 82 0.48 20.75 39.59
64 INT68975 Gene_expression of Mmp9 111 0.78 79.57 38.55
65 INT4925 Binding of Tacr1 57 0.48 17.39 38.38
66 INT65125 Gene_expression of Tacr1 81 0.77 23.9 38.35
67 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38
68 INT6417 Negative_regulation of ABAT 49 0.51 19.6 36.81
69 INT64558 Negative_regulation of Nos1 88 0.58 26.76 36.78
70 INT12608 Regulation of CNR1 62 0.60 24.36 36.02
71 INT23330 Binding of Chrna7 79 0.48 10.06 35.5
72 INT7326 Transcription of Th 83 0.72 13.5 35.33
73 INT3679 Gene_expression of AVP 171 0.78 72.9 35.23
74 INT4892 Positive_regulation of Gene_expression of Tacr1 56 0.69 25.64 34.69
75 INT66005 Regulation of Cnr1 47 0.61 19.21 34.52
76 INT8905 Gene_expression of EDN1 215 0.78 157.1 34.19
77 INT50308 Binding of Cnr1 61 0.48 14.41 33.52
78 INT3913 Positive_regulation of ABAT 47 0.69 22.73 33.4
79 INT99610 Localization of MMP9 126 0.79 48.46 32.67
80 INT6683 Gene_expression of Drd2 64 0.78 11.31 32.28
81 INT73498 Gene_expression of IL13 117 0.44 83.85 32.26
82 INT73982 Gene_expression of Hmox1 141 0.78 119.43 32.17
83 INT29503 Gene_expression of Mmp2 95 0.77 56.92 31.68
84 INT86780 Positive_regulation of Hmox1 145 0.70 117.09 31.18
85 INT8027 Regulation of Gene_expression of Ngf 34 0.62 26.32 31.16
86 INT6558 Positive_regulation of Gene_expression of Th 56 0.70 9.64 30.89
87 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73
88 INT23435 Positive_regulation of NGF 54 0.70 32.41 30.11
89 INT68973 Positive_regulation of Mmp9 89 0.52 58.56 30.04
90 INT894 Binding of Avp 84 0.48 29.16 29.63
91 INT7956 Regulation of Gene_expression of Th 44 0.61 8.26 29.31
92 INT2912 Positive_regulation of Positive_regulation of Abat 29 0.66 6.48 27.54
93 INT111359 Localization of Cnr1 55 0.81 11.25 27.41
94 INT5604 Positive_regulation of Drd2 47 0.67 10.75 27.41
95 INT75418 Negative_regulation of Cnr1 41 0.59 14.65 27.28
96 INT8881 Regulation of Gene_expression of Tacr1 38 0.61 17.49 27.19
97 INT90313 Negative_regulation of Gene_expression of Casp3 57 0.57 22.23 26.77
98 INT73047 Positive_regulation of MMP9 133 0.68 73.22 26.42
99 INT63444 Regulation of Gene_expression of Abat 26 0.51 14.65 26.29
100 INT80791 Gene_expression of Slc6a3 113 0.78 11.89 25.76
101 INT74688 Regulation of Nos1 55 0.62 22.16 25.3
102 INT74377 Regulation of Cnr1 38 0.59 16.93 24.77
103 INT12484 Binding of Drd2 45 0.48 15.17 24.72
104 INT6726 Positive_regulation of Edn1 118 0.70 65.96 24.07
105 INT682 Negative_regulation of AVP 97 0.59 50.67 23.91
106 INT22549 Positive_regulation of Positive_regulation of Casp3 48 0.56 29.5 23.7
107 INT50970 Positive_regulation of Ntrk1 51 0.57 29.38 22.83
108 INT29704 Regulation of Casp3 51 0.56 22.13 22.79
109 INT26719 Negative_regulation of Gene_expression of Th 38 0.58 11.87 22.78
110 INT62373 Negative_regulation of NGF 34 0.59 25.87 22.38
111 INT74682 Positive_regulation of Mmp2 72 0.69 40.46 21.73
112 INT74059 Positive_regulation of Gene_expression of Nos1 55 0.70 11.5 21.39
113 INT61825 Negative_regulation of Slc6a3 47 0.59 6.52 21.27
114 INT13643 Phosphorylation of Th 20 0.82 1.9 20.97
115 INT6127 Regulation of Localization of AVP 60 0.62 15.12 20.84
116 INT56769 Gene_expression of Ntrk1 36 0.77 15.79 20.75
117 INT49774 Binding of DRD2 48 0.48 17.42 20.73
118 INT31874 Negative_regulation of Gene_expression of Abat 31 0.42 12.22 20.31
119 INT10442 Negative_regulation of CNR1 47 0.59 20.88 20.2
120 INT65907 Negative_regulation of Gene_expression of Ngf 36 0.59 19.5 20.03
121 INT7470 Positive_regulation of Gene_expression of Avp 37 0.70 19.55 19.96
122 INT41494 Negative_regulation of Gene_expression of Tacr1 25 0.58 11.73 19.91
123 INT5499 Transcription of Avp 52 0.72 7.98 19.87
124 INT64261 Negative_regulation of Positive_regulation of Ngf 21 0.59 16.28 19.78
125 INT8662 Positive_regulation of EDN1 144 0.70 125.34 19.59
126 INT5048 Binding of Edn1 55 0.47 18.86 19.16
127 INT79955 Localization of Cnr1 26 0.81 8.44 19.06
128 INT93734 Positive_regulation of Gene_expression of Bcl2 76 0.70 61.95 18.46
129 INT18621 Binding of ABAT 28 0.36 9.88 18.04
130 INT49922 Positive_regulation of Positive_regulation of Ngf 21 0.67 14.46 17.68
131 INT80223 Positive_regulation of Hmox1 128 0.68 77.71 17.64
132 INT86673 Positive_regulation of Bcl2 77 0.70 57.74 17.37
133 INT50972 Negative_regulation of Ntrk1 39 0.51 32.22 17.29
134 INT76406 Gene_expression of Hmox1 140 0.78 85.86 17.15
135 INT15358 Transcription of Ngf 29 0.72 10.43 16.94
136 INT65214 Binding of Slc6a3 54 0.48 4.77 16.79
137 INT213 Negative_regulation of Localization of AVP 46 0.59 19.78 16.79
138 INT22547 Regulation of Gene_expression of Casp3 23 0.62 8.04 16.78
139 INT6129 Positive_regulation of Localization of AVP 63 0.70 30.44 16.64
140 INT20216 Localization of NGF 40 0.80 18.16 16.61
141 INT15202 Regulation of Tacr1 26 0.60 9.65 16.48
142 INT84924 Positive_regulation of Gene_expression of NGF 29 0.68 17.91 16.46
143 INT87932 Positive_regulation of Gene_expression of Cnr1 28 0.69 8.86 16.38
144 INT62629 Localization of CNR1 35 0.76 11.86 16.3
145 INT103245 Positive_regulation of Gene_expression of MMP9 64 0.68 36.86 15.7
146 INT75434 Gene_expression of Il13 27 0.52 26.19 15.4
147 INT54356 Regulation of Slc6a3 48 0.58 5.86 15.24
148 INT71634 Gene_expression of SLC6A3 45 0.78 13.48 15.23
149 INT74098 Negative_regulation of Gene_expression of Nos1 36 0.59 16.25 14.82
150 INT71150 Binding of NGF 22 0.46 13.67 14.81
151 INT9191 Localization of EDN1 94 0.81 57.01 14.78
152 INT8904 Positive_regulation of Gene_expression of EDN1 66 0.70 65.4 14.42
153 INT34952 Regulation of ABAT 28 0.61 6.05 14.39
154 INT100938 Positive_regulation of Il13 47 0.69 42.11 14.36
155 INT80228 Positive_regulation of Gene_expression of Hmox1 68 0.70 62.88 14.01
156 INT51158 Positive_regulation of Tacr1 33 0.70 15.22 13.91
157 INT5806 Regulation of Edn1 63 0.62 23.46 13.88
158 INT6365 Localization of Edn1 56 0.81 18.84 13.83
159 INT74375 Positive_regulation of Gene_expression of Cnr1 24 0.70 14.25 13.66
160 INT120901 Positive_regulation of Gene_expression of Il13 36 0.57 31.63 13.36
161 INT5599 Regulation of Drd2 25 0.52 3.07 13.31
162 INT80222 Negative_regulation of Bcl2 82 0.58 69.16 13.18
163 INT116528 Gene_expression of HMOX1 106 0.78 86.13 12.8
164 INT49041 Transcription of Tacr1 25 0.72 12.52 12.8
165 INT31368 Positive_regulation of Positive_regulation of Th 19 0.51 2.2 12.68
166 INT21979 Negative_regulation of EDN1 52 0.58 24.65 12.55
167 INT28458 Localization of Slc6a3 31 0.76 2.33 12.49
168 INT57580 Positive_regulation of TACR1 18 0.69 9.35 12.47
169 INT69763 Positive_regulation of Positive_regulation of Cnr1 12 0.50 9.05 12.46
170 INT49975 Binding of SLC6A3 34 0.47 9.86 12.41
171 INT11141 Negative_regulation of Gene_expression of Avp 23 0.59 3.85 12.19
172 INT93715 Negative_regulation of MMP9 69 0.55 36.05 11.73
173 INT13743 Regulation of Gene_expression of Avp 30 0.62 6.9 11.66
174 INT81640 Positive_regulation of Gene_expression of Bcl2 106 0.69 84.58 11.63
175 INT68976 Positive_regulation of Gene_expression of Mmp9 34 0.42 28.21 11.28
176 INT64225 Positive_regulation of Localization of ABAT 15 0.60 4.46 11.28
177 INT48691 Negative_regulation of Tacr1 20 0.59 4.96 11.25
178 INT19575 Negative_regulation of Positive_regulation of Abat 14 0.43 2.07 11.05
179 INT141 Binding of Th 21 0.48 3.53 11.04
180 INT111223 Positive_regulation of HMOX1 47 0.70 39.14 10.92
181 INT8589 Positive_regulation of Positive_regulation of Tacr1 14 0.69 7.85 10.86
182 INT39016 Transcription of Abat 19 0.53 3.92 10.82
183 INT23519 Positive_regulation of Localization of Tacr1 12 0.41 3.84 10.82
184 INT15262 Negative_regulation of Positive_regulation of Avp 22 0.58 3.28 10.81
185 INT63773 Gene_expression of DRD2 25 0.78 10.41 10.8
186 INT74681 Positive_regulation of Gene_expression of Mmp2 23 0.55 15.58 10.74
187 INT23675 Negative_regulation of Binding of Chrna7 18 0.37 0.5 10.74
188 INT71633 Negative_regulation of SLC6A3 25 0.59 10.5 10.69
189 INT90114 Regulation of Gene_expression of Nos1 18 0.62 6.38 10.52
190 INT85048 Regulation of NGF 19 0.62 11.61 10.5
191 INT29705 Regulation of Positive_regulation of Casp3 13 0.48 5.37 10.45
192 INT89282 Regulation of MMP9 39 0.60 25.45 10.34
193 INT10184 Regulation of EDN1 44 0.62 23.78 10.06
194 INT48496 Regulation of Transcription of Th 16 0.54 2.29 10.02
195 INT106565 Negative_regulation of Gene_expression of Cnr1 19 0.59 6.98 9.93
196 INT51168 Localization of TACR1 10 0.80 7.66 9.83
197 INT126031 Negative_regulation of Gene_expression of MMP9 40 0.57 22.71 9.79
198 INT23676 Gene_expression of Chrna7 47 0.75 23.66 9.51
199 INT53547 Binding of TACR1 22 0.48 5.03 9.48
200 INT17764 Negative_regulation of Drd2 17 0.42 4.63 9.46
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