GO:0035097

From wiki-pain
Jump to: navigation, search
Name histone methyltransferase complex
Categary Component
Go Slim No
Go Link GO:0035097
Unique Molecular Interactions 121
Total Molecular Interactions 229
Total Single Events 664
Pain Genes Associated 10

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for histone methyltransferase complex. They are ordered first by their pain relevance and then by number of times they were reported for histone methyltransferase complex. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT306259 HDAC9 Negative_regulation of Gene_expression of TNF 1 0.21 0.89 0.78
2 INT168256 Binding of MLL and TNFRSF1B 1 0.00 1.2 0.53
3 INT304578 Negative_regulation of HDAC9 Positive_regulation of Gene_expression of Bdnf 1 0.06 0.9 0.49
4 INT321598 Binding of MLL and TNF 1 0.05 1.07 0.49
5 INT125568 Binding of Casr and Ncoa6 3 0.50 1.13 0.46
6 INT330464 Setd1a Regulation of Gene_expression of RT1-CE1 1 0.00 0.47 0.35
7 INT333893 Negative_regulation of HDAC9 Negative_regulation of Gene_expression of TNF 1 0.09 1.03 0.34
8 INT125567 Ncoa6 Positive_regulation of Casr 1 0.52 0.46 0.3
9 INT346957 HDAC9 Positive_regulation of Gene_expression of GSR 1 0.03 1.28 0.27
10 INT277613 Binding of HDAC9 and Runx2 1 0.02 0.59 0.26
11 INT97691 Binding of REST and HDAC9 1 0.26 0.09 0.23
12 INT330463 Setd1a Positive_regulation of Regulation of Adh1 1 0.00 0.09 0.23
13 INT225607 Ncoa6 Regulation of Gene_expression of Casr 1 0.15 0.68 0.17
14 INT225608 Ppara Regulation of Ncoa6 1 0.27 0.44 0.14
15 INT136880 Pebp1 Positive_regulation of Localization of Ncoa6 1 0.33 0.06 0.13
16 INT136876 Ncoa6 Regulation of Localization of Casr 1 0.62 0 0.12
17 INT146181 Kdm6a Negative_regulation of Gene_expression of KRT6A 1 0.03 0.31 0.11
18 INT232653 Binding of CD2 and MLL 1 0.02 0.27 0.1
19 INT215461 Binding of MLL and TNFSF13B 1 0.01 1.62 0.1
20 INT48194 Pdgfb Positive_regulation of Setd1a 1 0.23 0 0.09
21 INT67243 Ncoa6 Positive_regulation of Localization of Ins1 1 0.22 0.1 0.08
22 INT351011 Binding of HDAC9 and TSPYL2 1 0.04 0.63 0.08
23 INT136875 Pebp1 Regulation of Localization of Ncoa6 1 0.37 0 0.06
24 INT156144 MLL Positive_regulation of Epcam 1 0.00 0.47 0.06
25 INT312940 Chol1 Positive_regulation of Setd1a 1 0.00 0 0.06
26 INT136881 Ncoa6 Regulation of Pebp1 1 0.22 0 0.06
27 INT156143 MLL Positive_regulation of PECAM1 1 0.00 0.47 0.06
28 INT136879 Ncoa6 Regulation of Localization of Pebp1 1 0.37 0 0.06
29 INT339979 Binding of PRDX2 and HDAC9 1 0.02 0.16 0.05
30 INT125570 Ncoa6 Positive_regulation of Nr1i3 1 0.12 0 0.05
31 INT225556 Binding of Ncoa6 and Cytip 1 0.12 1.7 0.04
32 INT225569 Binding of Ncoa6 and Ep300 1 0.18 0.63 0.04
33 INT225485 Binding of Acsl1 and Ncoa6 1 0.01 0 0
34 INT197808 Binding of MEN1 and NME1 1 0.00 1.81 0
35 INT225610 Ncoa6 Regulation of Rb1 1 0.03 0.21 0
36 INT192046 Negative_regulation of Binding of RYR2 and Cbx5 1 0.01 1.12 0
37 INT197809 Binding of MEN1 and VIM 1 0.04 0.52 0
38 INT225559 Binding of Esr1 and Ncoa6 1 0.18 0 0
39 INT225565 Ncoa6 Regulation of Creb1 1 0.06 0.21 0
40 INT197810 Binding of MEN1 and MUC1 1 0.06 0.47 0
41 INT225520 Binding of Ncoa2 and Ncoa6 1 0.05 0.11 0
42 INT225606 Ncoa6 Regulation of Atf2 1 0.05 0.21 0
43 INT225560 Ncoa6 Positive_regulation of nr 1 0.09 0 0
44 INT225589 Ncoa6 Positive_regulation of Binding of nr 1 0.10 0 0
45 INT225505 Ncoa6 Positive_regulation of Positive_regulation of Tfrc 1 0.10 0 0
46 INT287875 EP300 Negative_regulation of HDAC9 1 0.04 0.51 0
47 INT225584 Ncoa6 Negative_regulation of Gfer 1 0.04 0.2 0
48 INT225570 Ncoa6 Regulation of Sox9 1 0.16 0.72 0
49 INT225593 Ncoa6 Positive_regulation of Prkdc 1 0.02 0 0
50 INT225539 D0Nrs1 Positive_regulation of Ncoa6 1 0.03 0.37 0
51 INT197816 Binding of MEN1 and NFKB1 1 0.05 0.07 0
52 INT225581 Binding of Emr1 and Ncoa6 1 0.01 0 0
53 INT197813 Binding of AMBP and MEN1 1 0.00 0.51 0
54 INT284917 RUNX1T1 Regulation of HDAC9 1 0.19 1.09 0
55 INT225500 Negative_regulation of Ncoa6 Positive_regulation of gr 1 0.09 0 0
56 INT225561 Binding of Tfrc and Ncoa6 1 0.07 0 0
57 INT225575 Ncoa6 Positive_regulation of gr 1 0.10 0 0
58 INT225564 Ncoa6 Regulation of Trp53 1 0.04 0.93 0
59 INT225601 Binding of D0Nrs1 and Ncoa6 1 0.04 0.84 0
60 INT225566 Ncoa6 Regulation of Stat2 1 0.14 0.21 0
61 INT225509 Negative_regulation of Binding of nr and Ncoa6 1 0.11 0.79 0
62 INT225609 Negative_regulation of Binding of Ncoa6 and Asc2 1 0.14 0.79 0
63 INT225536 Ncoa6 Positive_regulation of Localization of Ide 1 0.02 0.41 0
64 INT197817 Binding of JUND and MEN1 1 0.18 0.14 0
65 INT225516 Ncoa6 Positive_regulation of D0Nrs1 1 0.04 0.3 0
66 INT225590 Ncoa6 Regulation of Srf 1 0.08 0.21 0
67 INT225532 Ncoa6 Regulation of Jun 1 0.03 0.21 0
68 INT225597 Binding of Gfer and Paxip1 1 0.02 0 0
69 INT225594 Ncoa6 Positive_regulation of Positive_regulation of Rars 1 0.28 0 0
70 INT225595 Ncoa6 Regulation of Nfkb1 1 0.04 0.21 0
71 INT297615 Binding of TSC1 and HDAC9 1 0.01 0.4 0
72 INT197844 Binding of MEN1 and Nfkb1 1 0.06 0.26 0
73 INT225551 Binding of Paxip1 and Ncoa6 1 0.26 0.47 0
74 INT225600 Binding of Ncoa6 and Asc2 1 0.12 0.78 0
75 INT312939 Binding of Hes3 and Setd1a 1 0.01 0.66 0
76 INT225508 Ncoa6 Positive_regulation of Jun 1 0.13 0 0
77 INT265383 Hsp90aa1 Negative_regulation of HDAC9 1 0.06 0.7 0
78 INT225530 Binding of Gfer and Ncoa6 1 0.04 0.46 0
79 INT225557 Ncoa6 Positive_regulation of Pprc1 1 0.01 0.3 0
80 INT225604 Ncoa6 Positive_regulation of Positive_regulation of gr 1 0.12 0 0
81 INT225528 Ncoa6 Positive_regulation of Nfkb1 1 0.08 0 0
82 INT225515 Binding of Ncoa6 and Rbm39 1 0.14 0.26 0
83 INT225558 Binding of Ncoa6 and Pprc1 1 0.01 0.47 0
84 INT192043 Binding of RYR2 and Cbx5 1 0.01 1.12 0
85 INT355201 Binding of HDAC9 and Gopc 1 0.01 0.06 0
86 INT326197 Negative_regulation of HDAC9 Negative_regulation of EPHB2 1 0.17 0.15 0
87 INT225526 Binding of Ncoa6 and Zfp335 1 0.04 0.26 0
88 INT312945 ANTXR1 Regulation of Setd1a 1 0.00 0.36 0
89 INT225552 Binding of nr and Ncoa6 1 0.09 1.04 0
90 INT225599 Ncoa6 Negative_regulation of Paxip1 1 0.26 0.2 0
91 INT197815 Binding of MEN1 and TGFB1 1 0.16 0.13 0
92 INT225537 Binding of Paxip1 and Mll2 1 0.12 0 0
93 INT225602 Positive_regulation of Binding of Ncoa6 and Cytip 1 0.17 0 0
94 INT225598 Binding of Set and Ncoa6 1 0.10 0.26 0
95 INT227843 Binding of ERCC6 and MLL 1 0.00 0.34 0
96 INT225625 Binding of MED23 and Ncoa6 1 0.40 0.41 0
97 INT225577 Ncoa6 Positive_regulation of Localization of D0Nrs1 1 0.03 0.17 0
98 INT225527 Ncoa6 Positive_regulation of Creb1 1 0.12 0 0
99 INT225605 Binding of Ncoa6 and Positive_regulation of Esr1 1 0.25 0 0
100 INT254850 Setd1a Negative_regulation of Rac1 1 0.00 0 0
101 INT225514 Negative_regulation of Binding of D0Nrs1 and Ncoa6 1 0.02 0 0
102 INT200724 HDAC9 Positive_regulation of TP53 1 0.36 0.27 0
103 INT197814 Binding of MEN1 and RELA 1 0.42 0.07 0
104 INT194925 Binding of CD22 and MLL2 1 0.08 0.18 0
105 INT225499 Ncoa6 Positive_regulation of Positive_regulation of D0Nrs1 1 0.03 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for histone methyltransferase complex. They are ordered first by their pain relevance and then by number of times they were reported in histone methyltransferase complex. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT133647 Negative_regulation of HDAC9 149 0.57 106.84 17.9
2 INT192225 Gene_expression of HDAC9 35 0.58 32.82 6.36
3 INT97692 Positive_regulation of HDAC9 17 0.45 14.88 5.11
4 INT66347 Gene_expression of MLL 29 0.65 14.82 3.18
5 INT133648 Regulation of HDAC9 14 0.60 10.01 2.18
6 INT191154 Binding of HDAC9 20 0.36 14.12 1.83
7 INT332792 Positive_regulation of Gene_expression of HDAC9 5 0.45 4.61 1.44
8 INT48192 Gene_expression of Setd1a 8 0.42 4.41 1.26
9 INT258053 Positive_regulation of Negative_regulation of HDAC9 8 0.27 7.37 1.23
10 INT31014 Negative_regulation of Setd1a 4 0.27 1.11 0.88
11 INT197832 Localization of MEN1 1 0.80 11.01 0.63
12 INT125565 Gene_expression of Ncoa6 3 0.75 10.15 0.59
13 INT139312 Negative_regulation of Gene_expression of MLL 2 0.00 1.22 0.56
14 INT168257 Binding of MLL 4 0.02 4.25 0.53
15 INT67242 Localization of Ncoa6 6 0.72 2.21 0.52
16 INT78201 Regulation of MLL 2 0.02 0.79 0.48
17 INT125559 Positive_regulation of Ncoa6 7 0.59 3.98 0.47
18 INT61102 Gene_expression of MEN1 12 0.78 17.7 0.43
19 INT125566 Binding of Ncoa6 2 0.47 5.64 0.43
20 INT156944 Positive_regulation of Setd1a 2 0.30 1.31 0.41
21 INT333915 Negative_regulation of Binding of HDAC9 1 0.21 0.83 0.41
22 INT156943 Negative_regulation of Negative_regulation of Setd1a 1 0.18 0.71 0.32
23 INT333912 Regulation of Positive_regulation of HDAC9 1 0.19 0.63 0.31
24 INT232656 Localization of MLL 2 0.05 2.33 0.29
25 INT156942 Positive_regulation of Gene_expression of Setd1a 1 0.21 0.58 0.28
26 INT234466 Regulation of Negative_regulation of HDAC9 2 0.25 1.82 0.26
27 INT234461 Negative_regulation of Gene_expression of HDAC9 5 0.24 2.74 0.24
28 INT125562 Positive_regulation of Gene_expression of Ncoa6 2 0.67 4.05 0.24
29 INT227872 Positive_regulation of MLL 7 0.01 2.44 0.19
30 INT136871 Positive_regulation of Localization of Ncoa6 1 0.47 0.08 0.18
31 INT48193 Regulation of Setd1a 3 0.15 0.92 0.17
32 INT133646 Positive_regulation of Regulation of HDAC9 1 0.49 0.83 0.17
33 INT225342 Negative_regulation of Ncoa6 1 0.49 1.75 0.1
34 INT346968 Positive_regulation of Transcription of HDAC9 1 0.22 0.21 0.07
35 INT197836 Positive_regulation of Gene_expression of MEN1 1 0.50 3.16 0.07
36 INT346969 Transcription of HDAC9 1 0.23 0.21 0.07
37 INT197828 Negative_regulation of MEN1 1 0.43 5.06 0.06
38 INT191153 Negative_regulation of Negative_regulation of HDAC9 1 0.09 0.57 0.05
39 INT326227 Phosphorylation of HDAC9 1 0.22 2.32 0.03
40 INT277612 Localization of HDAC9 3 0.45 0.55 0
41 INT265379 Positive_regulation of Binding of HDAC9 2 0.19 1.06 0
42 INT225415 Negative_regulation of Localization of Ncoa6 1 0.36 0.46 0
43 INT225390 Positive_regulation of Binding of Ncoa6 1 0.49 0.26 0
44 INT225387 Negative_regulation of Gene_expression of Ncoa6 1 0.41 0.76 0
45 INT225401 Phosphorylation of Ncoa6 1 0.79 0.43 0
46 INT197841 Positive_regulation of MEN1 1 0.41 2.38 0
47 INT225425 Transcription of Ncoa6 1 0.69 1.34 0
48 INT225320 Regulation of Ncoa6 1 0.60 2.67 0
49 INT326229 Regulation of Phosphorylation of HDAC9 1 0.07 0.48 0
50 INT86107 Regulation of Negative_regulation of Setd1a 1 0.04 0.14 0
51 INT239565 Localization of Setd1a 1 0.01 0.85 0
52 INT194935 Binding of MLL2 1 0.10 0.17 0
53 INT197843 Regulation of Localization of MEN1 1 0.45 0.24 0
54 INT326233 Negative_regulation of Phosphorylation of HDAC9 1 0.11 0 0
55 INT197838 Transcription of MEN1 1 0.69 0.13 0
56 INT225340 Negative_regulation of Binding of Ncoa6 1 0.42 0.05 0
57 INT328548 Negative_regulation of Gene_expression of Cbx5 1 0.05 0.08 0
58 INT328546 Gene_expression of Cbx5 1 0.07 0.08 0
59 INT225430 Gene_expression of Mll2 1 0.33 0 0
60 INT341085 Positive_regulation of Positive_regulation of MLL 1 0.01 0.15 0
61 INT225351 Regulation of Phosphorylation of Ncoa6 1 0.44 0 0
62 INT355200 Regulation of Gene_expression of HDAC9 1 0.14 1.77 0
63 INT197824 Positive_regulation of Transcription of MEN1 1 0.50 0.13 0
64 INT225407 Regulation of Binding of Ncoa6 1 0.44 0.16 0
65 INT225343 Regulation of Positive_regulation of Ncoa6 1 0.44 0 0
66 INT225428 Binding of Paxip1 1 0.21 0.44 0
67 INT197834 Binding of MEN1 1 0.48 3.32 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox