GO:0035108

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Name limb morphogenesis
Categary Process
Go Slim No
Go Link GO:0035108
Unique Molecular Interactions 238
Total Molecular Interactions 315
Total Single Events 2399
Pain Genes Associated 25

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for limb morphogenesis. They are ordered first by their pain relevance and then by number of times they were reported for limb morphogenesis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT250867 Fgf8 Positive_regulation of Protein_catabolism of Ecm1 1 0.06 4.35 2.14
2 INT145940 Binding of Gad1 and Abat 2 0.14 1.44 1.78
3 INT311914 Il1 Negative_regulation of Gene_expression of Col2a1 1 0.01 1.94 1.23
4 INT1619 Binding of Gad1 and Oprl1 1 0.14 0 1.13
5 INT1620 Negative_regulation of Binding of Gad1 and Oprl1 1 0.16 0 1.13
6 INT204551 Binding of Col2a1 and Positive_regulation of Cia1 1 0.03 1.74 1.03
7 INT250868 Fgf8 Positive_regulation of Gene_expression of Mmp3 1 0.15 1.73 0.93
8 INT308495 Pcsk5 Regulation of CFI 1 0.01 0.22 0.85
9 INT140985 Gli3 Regulation of Ihh 1 0.29 0.85 0.85
10 INT250861 Fgf8 Positive_regulation of Gene_expression of Ptger2 1 0.04 1.51 0.84
11 INT12137 Ngf Regulation of Gad1 1 0.27 0.67 0.83
12 INT314203 Nos2 Positive_regulation of Gli3 1 0.19 1.27 0.73
13 INT68561 Binding of Gli3 and Ust 1 0.01 0.68 0.68
14 INT259776 Fbn2 Regulation of Negative_regulation of Agtr1a 1 0.00 1.42 0.66
15 INT296793 Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.75 0.65
16 INT296790 Tlr9 Regulation of Bax 1 0.14 0.76 0.65
17 INT296791 Positive_regulation of Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.8 0.65
18 INT139079 Tnip1 Negative_regulation of Ptch1 1 0.20 0.63 0.62
19 INT112699 Bid Regulation of Bax 1 0.25 0.51 0.61
20 INT250852 Fgf8 Negative_regulation of Gene_expression of Ecm1 1 0.04 1.1 0.54
21 INT353978 Lmx1b Regulation of Gene_expression of Pet1 1 0.31 0.21 0.53
22 INT103535 Obfc1 Negative_regulation of Positive_regulation of Gad1 1 0.03 0.07 0.49
23 INT41174 Bak1 Regulation of Localization of Prl 1 0.02 0 0.46
24 INT238638 Gopc Negative_regulation of Gene_expression of Bax 1 0.04 0.85 0.45
25 INT12139 Ins1 Regulation of Gad1 1 0.15 0.33 0.42
26 INT55588 Drd2 Regulation of Transcription of Gad1 1 0.15 0.07 0.4
27 INT55589 Drd2 Regulation of Gad1 1 0.15 0.07 0.4
28 INT79504 Binding of Gad1 and Chat 1 0.35 0 0.38
29 INT250870 Fgf8 Positive_regulation of Ecm1 1 0.04 0.79 0.38
30 INT254344 Binding of Col2a1 and Ncoa5 1 0.00 0.98 0.35
31 INT155061 Stat3 Negative_regulation of Bax 1 0.22 3.71 0.34
32 INT55087 Binding of Gad1 and Penk 1 0.08 0 0.32
33 INT42253 Bbx Regulation of Gad1 1 0.15 0 0.3
34 INT250856 Fgf8 Positive_regulation of Localization of Mmp3 1 0.11 0.51 0.3
35 INT328224 Col2a1 Positive_regulation of Gene_expression of Mmp13 1 0.04 0.8 0.29
36 INT162599 Wnt5a Regulation of Gene_expression of IL4I1 1 0.00 0.1 0.28
37 INT250864 Fgf8 Positive_regulation of Positive_regulation of Ptger2 1 0.03 0.55 0.28
38 INT250854 Fgf8 Positive_regulation of Positive_regulation of Mmp3 1 0.11 0.55 0.28
39 INT356231 Binding of Gabrb3 and Gad1 1 0.32 1.25 0.23
40 INT353981 Gene_expression of Pet1 Positive_regulation of Lmx1b 1 0.53 0 0.23
41 INT250873 Fgf8 Positive_regulation of GAG 1 0.55 0.48 0.23
42 INT296372 Binding of IDUA and ACD 1 0.03 2.72 0.23
43 INT180247 Binding of Gad1 and Tbca 1 0.02 0.22 0.22
44 INT180248 Binding of Gad1 and Plp1 1 0.08 0.22 0.21
45 INT335888 Lrp5 Negative_regulation of Gene_expression of Tph1 1 0.22 0.15 0.21
46 INT256629 Binding of Ptch1 and Shh 7 0.42 4.22 0.19
47 INT155063 Csf2 Negative_regulation of Gene_expression of Bax 1 0.27 1.46 0.18
48 INT338443 Binding of Gad1 and Slc32a1 1 0.31 0.64 0.18
49 INT285026 Bak1 Regulation of Bcl2 1 0.09 0.71 0.17
50 INT285022 Regulation of Bak1 Regulation of Bcl2 1 0.09 0.71 0.17
51 INT155066 Csf2 Negative_regulation of Bax 1 0.12 1.89 0.17
52 INT349475 Regulation of Bax Regulation of Bcl2 1 0.07 1.35 0.17
53 INT285024 Bcl2 Regulation of Bak1 1 0.09 0.71 0.17
54 INT346305 Binding of ELANE and Col2a1 1 0.00 0.98 0.17
55 INT336891 Epo Negative_regulation of Transcription of Bax 1 0.10 0.68 0.16
56 INT349476 Bax Regulation of Bcl2 1 0.07 1.33 0.15
57 INT336337 Glp2r Positive_regulation of Gene_expression of Col2a1 1 0.01 0.7 0.14
58 INT250863 Fgf8 Positive_regulation of Ptger2 1 0.03 0.19 0.14
59 INT180252 Negative_regulation of Gad1 Positive_regulation of CP 1 0.03 0.75 0.14
60 INT273040 Vip Regulation of Bax 1 0.23 1.69 0.13
61 INT273041 Adcyap1 Regulation of Bax 1 0.21 1.69 0.13
62 INT345343 PTCH1 Regulation of Negative_regulation of SMO 1 0.09 2.3 0.13
63 INT226192 Protein_catabolism of Bax Positive_regulation of Gtf3a 1 0.00 0.53 0.12
64 INT285030 Binding of Bax and Slc25a4 1 0.03 0.84 0.11
65 INT250866 Binding of Fgfr4 and Fgf8 1 0.12 0.35 0.11
66 INT177490 Binding of Gad1 and Gad2 1 0.10 0.19 0.11
67 INT233510 Wnt5a Positive_regulation of Gene_expression of Il12a 1 0.03 0.33 0.1
68 INT250860 Fgf8 Regulation of Localization of Ptger2 1 0.02 0.13 0.1
69 INT262751 Binding of PTCH1 and SMO 1 0.25 1.29 0.1
70 INT250862 Fgf8 Regulation of Localization of Mmp3 1 0.13 0.13 0.1
71 INT250859 Fgf8 Negative_regulation of Gene_expression of Mmp3 1 0.09 0.12 0.09
72 INT250872 Fgf8 Positive_regulation of Mmp3 1 0.11 0.12 0.09
73 INT346304 Col2a1 Positive_regulation of Localization of PTGER2 1 0.00 0.18 0.09
74 INT204300 Bcl2 Negative_regulation of Positive_regulation of Bak1 1 0.02 1.13 0.09
75 INT270457 Binding of Ptch1 and Gli1 1 0.02 1.3 0.08
76 INT211960 Wnt5a Positive_regulation of Car2 1 0.13 0.38 0.08
77 INT322969 Binding of Gad1 and Fos 1 0.23 0.23 0.08
78 INT302290 Birc5 Regulation of BAK1 1 0.21 1.22 0.07
79 INT204301 Positive_regulation of Hrk Positive_regulation of Positive_regulation of Bak1 1 0.00 1.17 0.07
80 INT302131 Negative_regulation of SOD2 Regulation of BAK1 1 0.09 1.22 0.07
81 INT302289 Negative_regulation of Birc5 Regulation of BAK1 1 0.20 1.22 0.07
82 INT285025 Bnip3 Positive_regulation of Bak1 1 0.11 0.78 0.07
83 INT285032 Bnip3 Positive_regulation of Bax 1 0.28 0.77 0.07
84 INT340401 Positive_regulation of Bax Positive_regulation of Binding of Hrk 1 0.01 0.79 0.07
85 INT302128 SOD2 Regulation of BAK1 1 0.09 1.22 0.07
86 INT340395 Binding of Bax and Tg(CAG-EGFP)D4Nagy 1 0.02 0.43 0.07
87 INT303562 Binding of Fgf10 and Fgfr2 1 0.40 0.88 0.07
88 INT302147 PTGER2 Positive_regulation of BAK1 1 0.06 2.08 0.06
89 INT302138 PTGER2 Positive_regulation of Gene_expression of BAK1 1 0.06 2.08 0.06
90 INT346302 ELANE Regulation of Col2a1 1 0.00 0.3 0.05
91 INT250865 Binding of Fgf8 and Fgfr3 1 0.18 0.3 0.05
92 INT250855 Binding of Fgfr2 and Fgf8 1 0.12 0.3 0.05
93 INT249922 Binding of Pah and Asph 1 0.06 0.4 0.04
94 INT249921 Binding of Hif1a and Asph 1 0.05 0.41 0.04
95 INT340394 Binding of Bax and Bbc3 1 0.01 0.36 0.04
96 INT204298 Bid Positive_regulation of Binding of Bak1 1 0.05 0.57 0.04
97 INT346303 Binding of MR1 and Col2a1 1 0.00 0.09 0.04
98 INT322891 Sox9 Regulation of Transcription of Col2a1 1 0.10 0.12 0.04
99 INT172902 Binding of Bax and Bcl2 5 0.30 3.19 0.03
100 INT192164 Binding of BAK1 and BCL2 3 0.04 2.8 0.03
101 INT192167 Negative_regulation of Binding of BAK1 and BCL2 2 0.05 1.89 0.03
102 INT192165 Binding of BAK1 and BCL2L1 2 0.06 1.35 0.03
103 INT254433 Binding of Lrp5 and Sost 2 0.39 1.51 0.03
104 INT192166 Negative_regulation of Binding of BAK1 and BCL2L1 1 0.05 1.06 0.03
105 INT297737 Cbr1 Positive_regulation of Bax 1 0.06 0.53 0.03
106 INT255756 Ptch1 Positive_regulation of Phosphorylation of Pik3r1 1 0.16 1.08 0.03
107 INT224682 Mcl1 Regulation of Bak1 1 0.01 1.09 0.03
108 INT255733 Ptch1 Positive_regulation of Pik3r1 1 0.16 1.08 0.03
109 INT303563 Binding of Fgf10 and Dysf 1 0.00 0.44 0.03
110 INT311655 Shh Positive_regulation of Gene_expression of Fgf8 1 0.31 0.18 0.03
111 INT333259 Bcl2 Regulation of Bax 1 0.03 0.32 0.03
112 INT224689 Binding of Bak1 and Mcl1 1 0.01 1.09 0.03
113 INT224676 Binding of Bax and Mcl1 1 0.01 1.09 0.03
114 INT333249 Cxcl12 Positive_regulation of Positive_regulation of Bak1 1 0.30 0.32 0.03
115 INT224690 Mcl1 Regulation of Bax 1 0.00 1.09 0.03
116 INT333262 Bcl2 Regulation of Bak1 1 0.04 0.31 0.03
117 INT341376 Sod2 Regulation of Bax 1 0.09 0.99 0.03
118 INT283013 Binding of Bak1 and Bcl2 4 0.06 1.03 0
119 INT185852 Binding of BAK1 and BAX 3 0.29 2.5 0
120 INT254434 Binding of Lrp5 and Best1 3 0.29 2.53 0
121 INT172906 Binding of Bax and Bcl2l1 2 0.16 2.03 0
122 INT185851 BID Positive_regulation of BAK1 1 0.43 0.73 0
123 INT267117 Lmx1b Regulation of Col7a1 1 0.02 1.29 0
124 INT255758 Ptch1 Positive_regulation of Akt1 1 0.21 1.14 0
125 INT342385 Positive_regulation of Binding of Lrp5 and Vdr 1 0.53 0.98 0
126 INT285029 Binding of Bax and Bcl2l1 1 0.25 0.1 0
127 INT255732 Ptch1 Positive_regulation of hs 1 0.06 1.26 0
128 INT330047 Binding of Bax and Bcl2l11 1 0.13 0.62 0
129 INT191058 Binding of Bcl2 and Positive_regulation of Gene_expression of Bax 1 0.21 0.49 0
130 INT333258 Gene_expression of Cxcl12 Positive_regulation of Positive_regulation of Bak1 1 0.15 0.55 0
131 INT254707 Positive_regulation of Map2k1 Regulation of Gene_expression of BAK1 1 0.05 0.67 0
132 INT322658 Binding of Bak1 and Prdm8 1 0.02 0.89 0
133 INT302321 Negative_regulation of Binding of Lrp6 and SOST 1 0.16 0.26 0
134 INT244846 Lbx1 Positive_regulation of Lmx1b 1 0.40 0 0
135 INT205975 Binding of PTCH1 and Smo 1 0.02 0.72 0
136 INT302322 Negative_regulation of Binding of Lrp5 and SOST 1 0.16 0.26 0
137 INT104029 RPGRIP1L Negative_regulation of Gene_expression of LTB 1 0.16 0.06 0
138 INT242483 Negative_regulation of Ciapin1 Negative_regulation of Positive_regulation of Bax 1 0.17 1.76 0
139 INT335884 Akt1 Regulation of Positive_regulation of Wnt5a 1 0.03 0.15 0
140 INT136914 Mapk8 Positive_regulation of Localization of Bax 1 0.51 0.12 0
141 INT302137 Binding of BAD and BAK1 1 0.07 0.93 0
142 INT314682 Binding of TBX2 and TBX4 1 0.16 0.84 0
143 INT255755 Ptch1 Regulation of Positive_regulation of Ins1 1 0.05 0.28 0
144 INT63391 SLTM Regulation of Gene_expression of Col2a1 1 0.00 0 0
145 INT205958 GLI1 Positive_regulation of Gene_expression of PTCH1 1 0.35 0.57 0
146 INT322664 Prdm8 Positive_regulation of Gene_expression of Bax 1 0.01 1.1 0
147 INT205960 Binding of PTCH1 and SHH 1 0.21 0.71 0
148 INT285028 Binding of Bcl2 and Bax 1 0.32 0.1 0
149 INT270461 Shh Regulation of Gene_expression of Ptch1 1 0.48 0.07 0
150 INT267115 Lmx1b Regulation of Gene_expression of Col4a1 1 0.09 1.37 0
151 INT255753 Ptch1 Positive_regulation of Phosphorylation of Gopc 1 0.13 1.33 0
152 INT302320 Binding of Lrp6 and SOST 1 0.18 0.26 0
153 INT229821 Fos Positive_regulation of Bax 1 0.15 0.27 0
154 INT342381 Binding of Lrp5 and Vdr 1 0.55 0.97 0
155 INT322668 Prdm8 Positive_regulation of Gene_expression of Bak1 1 0.02 1.1 0
156 INT309517 Binding of Bax and Xrcc6 1 0.15 0.5 0
157 INT201761 BIK Positive_regulation of Positive_regulation of Bax 1 0.01 0.43 0
158 INT147529 TGFB1 Negative_regulation of Gene_expression of Col2a1 1 0.05 0.32 0
159 INT335887 Akt1 Regulation of Lrp6 1 0.06 0.15 0
160 INT330052 Binding of Bax and Bid 1 0.15 0.62 0
161 INT342382 Binding of Car1 and Lrp5 1 0.40 0.9 0
162 INT322662 Binding of Bax and Pbrm1 1 0.08 0.9 0
163 INT172908 Binding of Bad and Bax 1 0.01 1.34 0
164 INT330057 Bid Positive_regulation of Bax 1 0.19 0.62 0
165 INT302319 Binding of Lrp5 and SOST 1 0.18 0.26 0
166 INT283002 Binding of Bak1 and Mgst1 1 0.01 0.24 0
167 INT313426 Positive_regulation of Ppp2ca Positive_regulation of Bax 1 0.46 0.36 0
168 INT335883 Binding of Lrp6 and Wnt5a 1 0.27 0.08 0
169 INT267116 Binding of Lmx1b and Nps 1 0.30 1.95 0
170 INT267252 Bax Regulation of Bak1 1 0.05 1.09 0
171 INT259049 Binding of BAK1 and HPV18I1 1 0.00 1.19 0
172 INT335891 Binding of Dkk1 and Lrp5 1 0.39 0.57 0
173 INT201765 Binding of BCL2L1 and Bax 1 0.00 0.28 0
174 INT260074 Binding of BRCA2 and PTCH1 1 0.40 0.15 0
175 INT256632 Binding of PTCH1 and Jkamp 1 0.00 2.32 0
176 INT352151 Binding of Bak1 and Gopc 1 0.02 0.26 0
177 INT201763 BID Positive_regulation of Positive_regulation of Bax 1 0.01 0.43 0
178 INT242476 Negative_regulation of Ciapin1 Positive_regulation of Bax 1 0.19 1.29 0
179 INT322670 Prdm8 Positive_regulation of Bax 1 0.01 1.1 0
180 INT275753 xn Regulation of Bax 1 0.05 1.31 0
181 INT333681 Trp53 Regulation of Negative_regulation of Bax 1 0.15 1.17 0
182 INT255744 Binding of hs and Ptch1 1 0.06 1.32 0
183 INT334718 Binding of NOS1 and Bax 1 0.02 0.87 0
184 INT202675 Fgf10 Positive_regulation of Fgfr2 1 0.45 0.07 0
185 INT267119 Lmx1b Regulation of Regulation of Col4a1 1 0.09 0.67 0
186 INT330054 Bcl2l11 Positive_regulation of Bax 1 0.25 0.62 0
187 INT205965 Binding of Ptch1 and Smo 1 0.03 0.72 0
188 INT270466 Ptch1 Regulation of Gene_expression of Shh 1 0.48 0.07 0
189 INT255750 Ptch1 Positive_regulation of Ins1 1 0.10 0.35 0
190 INT260073 Binding of FANCC and PTCH1 1 0.33 0.49 0
191 INT322666 Binding of Bak1 and Pbrm1 1 0.20 0.9 0
192 INT254090 EPO Negative_regulation of Gene_expression of Bax 1 0.10 0.63 0
193 INT340400 Binding of Bax and Mom6 1 0.04 0.28 0
194 INT275746 Binding of xn and Bax 1 0.05 2.57 0
195 INT322663 Prdm8 Positive_regulation of Bak1 1 0.01 1.1 0
196 INT340399 Binding of Bak1 and Bax 1 0.12 0.91 0
197 INT267118 Lmx1b Regulation of Regulation of Col7a1 1 0.06 0.47 0
198 INT309518 Negative_regulation of Binding of Bax and Xrcc6 1 0.16 0.25 0
199 INT260067 Binding of PTCH1 and XPA 1 0.26 1.08 0
200 INT205976 Binding of Ptch1 and SMOX 1 0.21 0.72 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for limb morphogenesis. They are ordered first by their pain relevance and then by number of times they were reported in limb morphogenesis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT26788 Gene_expression of Gad1 93 0.78 27.05 42.71
2 INT10453 Positive_regulation of Gad1 65 0.70 10.75 31.9
3 INT1616 Regulation of Gad1 46 0.61 10.2 28.64
4 INT100423 Gene_expression of Bax 141 0.75 98.43 24.48
5 INT16326 Transcription of Gad1 58 0.71 15.78 20.45
6 INT22143 Gene_expression of Gad1 35 0.76 14.4 15.4
7 INT109511 Gene_expression of Bax 133 0.78 113.22 14.36
8 INT37618 Gene_expression of Col2a1 50 0.70 33.88 11.58
9 INT102110 Positive_regulation of Gene_expression of Bax 42 0.67 35.77 9.51
10 INT336 Negative_regulation of Gad1 19 0.58 7.71 9.51
11 INT54834 Gene_expression of Col2a1 48 0.72 13.5 9.41
12 INT102106 Positive_regulation of Bax 48 0.67 30.62 9.28
13 INT80037 Gene_expression of BAK1 58 0.75 39.49 9.08
14 INT26789 Positive_regulation of Gene_expression of Gad1 22 0.70 7.39 9.02
15 INT102107 Negative_regulation of Gene_expression of Bax 30 0.57 29.48 7.33
16 INT98837 Positive_regulation of Bax 72 0.61 63.14 6.41
17 INT250832 Gene_expression of Fgf8 1 0.77 13.36 6.2
18 INT49011 Regulation of Gene_expression of Gad1 10 0.62 0.55 6.07
19 INT145929 Regulation of Bax 20 0.60 18.12 5.35
20 INT123422 Gene_expression of Lmx1b 18 0.78 6.93 5.17
21 INT109513 Positive_regulation of Gene_expression of Bax 37 0.67 29.52 5.06
22 INT68559 Negative_regulation of Gli3 5 0.37 4.56 4.93
23 INT66388 Positive_regulation of Transcription of Gad1 14 0.67 2.45 4.67
24 INT99504 Negative_regulation of Bax 19 0.56 8.89 4.44
25 INT103345 Positive_regulation of Gene_expression of BAK1 10 0.57 6.4 4.19
26 INT123752 Regulation of Bax 19 0.60 16.45 4
27 INT112692 Localization of Bax 31 0.80 20.97 3.98
28 INT124815 Binding of Col2a1 9 0.37 10.27 3.93
29 INT42251 Regulation of Gad1 10 0.44 5.25 3.45
30 INT39867 Binding of Col2a1 9 0.35 7.65 3.18
31 INT54832 Negative_regulation of Gene_expression of Col2a1 6 0.50 2.53 3.16
32 INT171884 Positive_regulation of Gene_expression of Col2a1 11 0.23 8.04 3.02
33 INT67952 Regulation of Transcription of Gad1 6 0.51 1.23 2.98
34 INT54170 Positive_regulation of Positive_regulation of Gad1 5 0.69 0 2.89
35 INT259760 Localization of Fbn2 5 0.05 5.55 2.85
36 INT74293 Positive_regulation of BAK1 13 0.60 14.13 2.73
37 INT259762 Positive_regulation of Fbn2 4 0.05 6.74 2.55
38 INT42255 Negative_regulation of Gad1 7 0.56 4.83 2.54
39 INT126581 Positive_regulation of Gli3 6 0.35 1.59 2.48
40 INT90566 Positive_regulation of Gene_expression of Gad1 5 0.48 1.46 2.42
41 INT102146 Phosphorylation of Bax 4 0.66 3.48 2.35
42 INT67951 Negative_regulation of Gene_expression of Gad1 4 0.43 1.08 2.13
43 INT144364 Negative_regulation of Lmx1b 5 0.45 3.35 2.12
44 INT154970 Localization of Bax 15 0.74 11.12 2.11
45 INT42256 Positive_regulation of Gad1 4 0.66 1.1 2.09
46 INT126374 Gene_expression of Gli3 6 0.77 3.67 2.02
47 INT44109 Localization of Gad1 7 0.74 1.06 1.97
48 INT98836 Transcription of Bax 6 0.69 5.04 1.96
49 INT134442 Transcription of Bax 14 0.67 7.6 1.9
50 INT135540 Negative_regulation of Bax 16 0.48 11.8 1.89
51 INT134443 Binding of Bax 10 0.47 5.62 1.84
52 INT55587 Negative_regulation of Positive_regulation of Gad1 6 0.49 1.1 1.82
53 INT164407 Negative_regulation of Gene_expression of Col2a1 6 0.39 4 1.78
54 INT104883 Positive_regulation of Positive_regulation of Bax 4 0.45 4.05 1.74
55 INT250841 Positive_regulation of Gene_expression of Fgf8 1 0.69 3.8 1.72
56 INT220992 Protein_catabolism of Col2a1 8 0.40 5.55 1.64
57 INT103967 Negative_regulation of Gene_expression of BAK1 8 0.42 7.02 1.54
58 INT164410 Negative_regulation of Col2a1 4 0.39 3.75 1.53
59 INT259766 Positive_regulation of Localization of Fbn2 1 0.03 3.09 1.51
60 INT62800 Regulation of BAK1 7 0.41 10.12 1.47
61 INT146785 Positive_regulation of Localization of Bax 7 0.69 6.16 1.47
62 INT140245 Binding of Gli3 3 0.36 2.65 1.46
63 INT109512 Negative_regulation of Gene_expression of Bax 12 0.42 8.04 1.44
64 INT32184 Negative_regulation of Col2a1 9 0.42 3.05 1.43
65 INT103531 Regulation of Positive_regulation of Gad1 3 0.61 0.31 1.43
66 INT113151 Positive_regulation of Ptch1 7 0.64 3.8 1.41
67 INT90567 Negative_regulation of Gene_expression of Gad1 4 0.41 2.88 1.36
68 INT96641 Transcription of Gad1 3 0.60 0.84 1.36
69 INT38990 Negative_regulation of IDUA 12 0.59 5.04 1.33
70 INT250850 Negative_regulation of Gene_expression of Fgf8 1 0.42 2.79 1.33
71 INT53548 Negative_regulation of Transcription of Gad1 3 0.43 0.46 1.32
72 INT54831 Regulation of Gene_expression of Col2a1 4 0.39 2.3 1.31
73 INT353966 Negative_regulation of Gene_expression of Lmx1b 1 0.43 0.16 1.31
74 INT1618 Binding of Gad1 6 0.37 2.01 1.3
75 INT112695 Negative_regulation of Protein_catabolism of Bax 3 0.36 1.72 1.3
76 INT142017 Positive_regulation of Positive_regulation of BAK1 2 0.52 1.74 1.3
77 INT139077 Negative_regulation of Ptch1 5 0.56 5.22 1.29
78 INT154969 Positive_regulation of Localization of Bax 4 0.64 3.42 1.27
79 INT38989 Gene_expression of IDUA 22 0.78 16.99 1.26
80 INT128714 Transcription of Col2a1 6 0.52 2.13 1.24
81 INT227150 Localization of Gad1 4 0.49 0.15 1.22
82 INT112693 Protein_catabolism of Bax 5 0.74 3.17 1.2
83 INT176463 Protein_catabolism of Col2a1 4 0.35 1.94 1.2
84 INT108519 Binding of Lrp6 8 0.44 1.47 1.19
85 INT141189 Negative_regulation of Transcription of Bax 1 0.41 1.42 1.14
86 INT250840 Negative_regulation of Fgf8 1 0.43 1.92 1.11
87 INT165513 Negative_regulation of Regulation of Gad1 1 0.41 1.59 1.11
88 INT54835 Regulation of Col2a1 5 0.59 2.08 1.07
89 INT277461 Positive_regulation of Gene_expression of Fgf8 1 0.24 0.47 1.05
90 INT93094 Gene_expression of Bak1 13 0.52 13.94 1.02
91 INT142813 Localization of RPGRIP1L 1 0.59 0.99 1.01
92 INT168233 Positive_regulation of Transcription of Col2a1 2 0.45 1.78 0.99
93 INT175507 Regulation of Gene_expression of Bax 13 0.50 10.91 0.95
94 INT296385 Binding of IDUA 12 0.39 20.73 0.93
95 INT90568 Regulation of Gene_expression of Gad1 3 0.27 0.46 0.89
96 INT135542 Positive_regulation of Bak1 17 0.43 16.12 0.88
97 INT180240 Binding of Gad1 7 0.47 2.99 0.86
98 INT53660 Positive_regulation of Pcsk5 2 0.49 0.29 0.85
99 INT135299 Binding of PTCH1 10 0.48 12.16 0.84
100 INT266562 Gene_expression of Fbn2 1 0.05 0.93 0.84
101 INT266563 Positive_regulation of Gene_expression of Fbn2 1 0.04 0.93 0.84
102 INT144697 Regulation of Gene_expression of Bax 8 0.37 9.5 0.81
103 INT173506 Positive_regulation of Col2a1 4 0.20 3.42 0.76
104 INT259763 Regulation of Fbn2 1 0.02 1.47 0.76
105 INT142416 Binding of Ptch1 6 0.34 4.92 0.74
106 INT14040 Binding of Bak1 2 0.30 0.55 0.72
107 INT37617 Regulation of Gene_expression of Col2a1 3 0.31 1.48 0.7
108 INT68560 Regulation of Gli3 3 0.18 1.51 0.68
109 INT14041 Regulation of Binding of Bak1 1 0.23 0 0.68
110 INT153257 Regulation of Ptch1 6 0.36 5.92 0.67
111 INT204290 Positive_regulation of Bak1 3 0.22 5.19 0.66
112 INT84250 Positive_regulation of IDUA 8 0.56 15.89 0.62
113 INT63389 Localization of Col2a1 7 0.68 1.95 0.6
114 INT267114 Positive_regulation of Lmx1b 2 0.50 0.96 0.6
115 INT259764 Negative_regulation of Positive_regulation of Fbn2 1 0.03 1.7 0.6
116 INT296583 Gene_expression of Fgf10 3 0.59 2.64 0.57
117 INT259765 Phosphorylation of Fbn2 1 0.05 0.99 0.57
118 INT65919 Gene_expression of Ptch1 11 0.75 6.47 0.56
119 INT296594 Regulation of Fgf10 1 0.15 1.53 0.56
120 INT285007 Regulation of Bak1 1 0.20 3.46 0.56
121 INT176242 Binding of Bax 10 0.42 10.18 0.52
122 INT123645 Negative_regulation of Transcription of Gad1 2 0.42 0.76 0.52
123 INT135062 Transcription of Gli3 1 0.05 0 0.52
124 INT135541 Negative_regulation of Bak1 6 0.30 4.52 0.49
125 INT32183 Positive_regulation of Negative_regulation of Col2a1 2 0.46 1.01 0.49
126 INT102108 Protein_catabolism of Bax 8 0.64 5.69 0.48
127 INT250845 Protein_catabolism of Fgf8 1 0.98 1.64 0.48
128 INT134446 Positive_regulation of Binding of Bax 1 0.49 0.72 0.48
129 INT268007 Gene_expression of Fgf8 8 0.72 1.38 0.47
130 INT125840 Positive_regulation of Binding of Col2a1 1 0.43 1.21 0.45
131 INT267113 Regulation of Gene_expression of Lmx1b 2 0.62 1.36 0.44
132 INT308493 Positive_regulation of Positive_regulation of Pcsk5 1 0.27 0 0.44
133 INT277465 Regulation of Gene_expression of Fgf8 2 0.25 0.43 0.43
134 INT152059 Regulation of Transcription of Bax 1 0.26 0.07 0.42
135 INT150946 Negative_regulation of Positive_regulation of Bak1 2 0.29 3.02 0.4
136 INT135802 Positive_regulation of Negative_regulation of Bax 2 0.41 0.57 0.4
137 INT123421 Binding of Lmx1b 1 0.36 0.54 0.35
138 INT204069 Negative_regulation of Positive_regulation of Bax 5 0.31 3.08 0.34
139 INT169538 Negative_regulation of Localization of Bax 3 0.49 1.41 0.34
140 INT259761 Negative_regulation of Fbn2 2 0.03 1.1 0.34
141 INT250826 Transcription of Fgf8 1 0.71 0.71 0.34
142 INT184482 Positive_regulation of Positive_regulation of Bax 5 0.41 4.7 0.33
143 INT172216 Binding of Bak1 5 0.25 8.48 0.33
144 INT221191 Negative_regulation of Localization of Bax 4 0.38 2.85 0.33
145 INT54833 Positive_regulation of Col2a1 5 0.52 1.1 0.32
146 INT93093 Regulation of Gene_expression of Bak1 3 0.30 2.09 0.32
147 INT122950 Binding of BAK1 16 0.41 12.85 0.31
148 INT140379 Positive_regulation of Gene_expression of Bak1 4 0.27 2.27 0.31
149 INT229853 Gene_expression of Bak1 2 0.25 2.04 0.29
150 INT297804 Regulation of Lrp5 6 0.60 2.31 0.27
151 INT102111 Positive_regulation of Protein_catabolism of Bax 2 0.45 1.14 0.27
152 INT335875 Regulation of Lrp6 1 0.57 0.43 0.27
153 INT183055 Gene_expression of PTCH1 10 0.77 15.54 0.26
154 INT254427 Binding of Lrp5 10 0.48 5.43 0.26
155 INT266560 Positive_regulation of Positive_regulation of Fbn2 1 0.05 0.5 0.26
156 INT181524 Negative_regulation of Binding of Col2a1 1 0.13 1.05 0.25
157 INT150947 Positive_regulation of Positive_regulation of Bak1 1 0.05 0.6 0.25
158 INT135061 Protein_catabolism of Gli3 1 0.04 0 0.25
159 INT250836 Binding of Fgf8 3 0.35 0.66 0.24
160 INT135543 Negative_regulation of Positive_regulation of Bax 5 0.30 6.4 0.23
161 INT257802 Positive_regulation of Transcription of Gad1 1 0.44 0 0.23
162 INT353973 Localization of Lmx1b 1 0.75 0.3 0.22
163 INT275310 Positive_regulation of Protein_catabolism of Col2a1 1 0.16 0.88 0.22
164 INT187555 Transcription of BAK1 3 0.19 2.6 0.21
165 INT187556 Regulation of Transcription of BAK1 1 0.02 1.22 0.21
166 INT250833 Localization of Fgf8 1 0.74 0.46 0.21
167 INT250842 Negative_regulation of Binding of Fgf8 1 0.43 0.33 0.21
168 INT282088 Localization of Bak1 6 0.54 3.78 0.19
169 INT84244 Positive_regulation of Gene_expression of IDUA 5 0.70 3.75 0.19
170 INT135060 Negative_regulation of Transcription of Gli3 1 0.03 0 0.19
171 INT254429 Negative_regulation of Lrp5 4 0.57 1.95 0.18
172 INT300463 Regulation of Regulation of Bax 1 0.29 1.33 0.18
173 INT198036 Negative_regulation of BAK1 5 0.27 5.98 0.17
174 INT180242 Positive_regulation of Binding of Gad1 1 0.49 0.86 0.17
175 INT335861 Localization of Lrp6 1 0.69 0.54 0.17
176 INT63646 Localization of Col2a1 3 0.77 0.37 0.16
177 INT267112 Regulation of Lmx1b 3 0.61 2.21 0.16
178 INT84247 Regulation of Gene_expression of IDUA 2 0.45 0.54 0.15
179 INT104557 Positive_regulation of Binding of Gad1 1 0.50 0.76 0.15
180 INT250835 Positive_regulation of Fgf8 1 0.50 0.42 0.14
181 INT320315 Protein_catabolism of BAK1 3 0.76 3.13 0.13
182 INT95278 Positive_regulation of Gene_expression of Col2a1 2 0.47 0.21 0.13
183 INT285005 Negative_regulation of Bak1 1 0.14 0.16 0.13
184 INT101575 Negative_regulation of Negative_regulation of Gad1 1 0.07 0.24 0.13
185 INT185872 Localization of BAK1 6 0.74 11.28 0.12
186 INT265485 Positive_regulation of Localization of BAK1 4 0.50 5.17 0.12
187 INT185907 Positive_regulation of Binding of BAK1 2 0.60 1.59 0.12
188 INT238490 Regulation of Regulation of BAK1 1 0.19 2.56 0.12
189 INT177493 Phosphorylation of Gad1 1 0.45 0.19 0.11
190 INT336888 Negative_regulation of Transcription of Bax 1 0.07 0.68 0.11
191 INT203079 Regulation of Transcription of Col2a1 1 0.05 0.07 0.11
192 INT270451 Localization of Gli3 1 0.26 0.63 0.11
193 INT162574 Gene_expression of Wnt5a 7 0.47 0.92 0.1
194 INT353970 Transcription of Lmx1b 1 0.72 0 0.1
195 INT233483 Regulation of Gene_expression of Wnt5a 1 0.19 0.33 0.1
196 INT260083 Regulation of PTCH1 11 0.27 4.46 0.09
197 INT304137 Regulation of Localization of Bax 2 0.24 1.7 0.09
198 INT270454 Regulation of Transcription of Ptch1 1 0.25 0.55 0.09
199 INT70641 Gene_expression of Pcsk5 1 0.21 0.18 0.09
200 INT135063 Regulation of Gene_expression of Gli3 1 0.04 0 0.09
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