GO:0035116

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Name embryonic hindlimb morphogenesis
Categary Process
Go Slim No
Go Link GO:0035116
Unique Molecular Interactions 335
Total Molecular Interactions 448
Total Single Events 3129
Pain Genes Associated 38

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for embryonic hindlimb morphogenesis. They are ordered first by their pain relevance and then by number of times they were reported for embryonic hindlimb morphogenesis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT250867 Fgf8 Positive_regulation of Protein_catabolism of Ecm1 1 0.06 4.35 2.14
2 INT338691 Binding of Trpv1 and Aff3 1 0.24 1.21 1.88
3 INT93470 Notch1 Positive_regulation of Localization of Prkcg 2 0.09 0.31 1.65
4 INT48881 TWIST1 Positive_regulation of Localization of Abat 1 0.02 0.44 1.29
5 INT115985 Cpe Positive_regulation of Binding of Gnas 1 0.00 0.17 1.28
6 INT65373 Notch1 Regulation of Oprd1 1 0.09 0 1.16
7 INT130627 Gnas Regulation of Prkaca 1 0.00 0 1.13
8 INT221 Chd7 Negative_regulation of Th 1 0.02 0 1.04
9 INT275097 Twist1 Regulation of Ltp 1 0.01 0.37 0.96
10 INT142709 Binding of TWIST1 and CEBPZ 2 0.17 1.16 0.95
11 INT250868 Fgf8 Positive_regulation of Gene_expression of Mmp3 1 0.15 1.73 0.93
12 INT74872 Igh-Dex Positive_regulation of Chd7 1 0.01 0.5 0.89
13 INT250861 Fgf8 Positive_regulation of Gene_expression of Ptger2 1 0.04 1.51 0.84
14 INT162241 Binding of COL7A1 and MMP13 2 0.03 0.86 0.73
15 INT243626 Twist1 Regulation of Hand1 1 0.15 1.55 0.72
16 INT123869 Binding of GNAS and OPRK1 1 0.00 0.37 0.7
17 INT338693 Aff3 Positive_regulation of Localization of CAP1 1 0.01 0.39 0.69
18 INT338690 Aff3 Positive_regulation of Trpv1 1 0.39 0.4 0.67
19 INT243639 Twist1 Negative_regulation of Gene_expression of Il2 1 0.24 1.28 0.65
20 INT329297 Binding of Cd226 and Aff3 1 0.18 1.54 0.64
21 INT182266 EDN1 Positive_regulation of Gene_expression of MMP13 1 0.35 2.03 0.63
22 INT178087 EDN1 Positive_regulation of MMP13 2 0.23 1.58 0.59
23 INT345303 MMP15 Positive_regulation of MMP13 1 0.00 1.18 0.58
24 INT102864 Prkaca Regulation of Twist1 1 0.48 0.05 0.58
25 INT250852 Fgf8 Negative_regulation of Gene_expression of Ecm1 1 0.04 1.1 0.54
26 INT202043 MMP13 Regulation of Protein_catabolism of COL2A1 1 0.01 0.54 0.54
27 INT165078 Binding of CTSB and Notch1 1 0.00 1.08 0.48
28 INT102364 BRD1 Positive_regulation of Twist1 1 0.00 0 0.47
29 INT117531 Twist1 Regulation of CSAD 1 0.00 0.85 0.47
30 INT345305 MMP14 Positive_regulation of MMP13 1 0.00 0.33 0.45
31 INT148377 PDP1 Positive_regulation of NOTCH1 1 0.44 0.64 0.44
32 INT148378 CP Positive_regulation of NOTCH1 1 0.11 0.64 0.44
33 INT338692 CAP1 Negative_regulation of Positive_regulation of Aff3 1 0.01 0.2 0.44
34 INT102862 Prkaca Regulation of Phosphorylation of Twist1 1 0.19 0.1 0.42
35 INT152158 NENF Regulation of TWIST1 1 0.01 0.33 0.4
36 INT312086 ELANE Positive_regulation of MMP13 1 0.13 0.64 0.39
37 INT330519 Binding of CD8A and DICER1 1 0.08 0.99 0.38
38 INT250870 Fgf8 Positive_regulation of Ecm1 1 0.04 0.79 0.38
39 INT300609 Binding of Ctnnb1 and Wnt2 1 0.02 0.25 0.37
40 INT168202 Msx1 Negative_regulation of Gene_expression of Mc1r 1 0.21 0.49 0.35
41 INT124378 Prodh2 Positive_regulation of Ctnnb1 1 0.00 0.59 0.35
42 INT243627 Twist1 Regulation of Gene_expression of Ik 1 0.01 0.13 0.34
43 INT194859 IL1B Positive_regulation of Gene_expression of MMP13 2 0.52 0.86 0.33
44 INT323870 LEP Regulation of Gene_expression of MMP13 1 0.21 1.76 0.33
45 INT243622 Twist1 Regulation of Jak2 1 0.30 0.2 0.32
46 INT243641 Twist1 Positive_regulation of Socs1 1 0.14 0.13 0.31
47 INT243634 Twist1 Regulation of Socs1 1 0.14 0.13 0.31
48 INT243625 Stat4 Positive_regulation of Gene_expression of Twist1 1 0.39 0.75 0.3
49 INT243630 Il12a Positive_regulation of Gene_expression of Twist1 1 0.18 0.69 0.3
50 INT250856 Fgf8 Positive_regulation of Localization of Mmp3 1 0.11 0.51 0.3
51 INT75056 Binding of MC1R and Msx1 1 0.00 0.17 0.29
52 INT250864 Fgf8 Positive_regulation of Positive_regulation of Ptger2 1 0.03 0.55 0.28
53 INT250854 Fgf8 Positive_regulation of Positive_regulation of Mmp3 1 0.11 0.55 0.28
54 INT336335 Glp2r Regulation of Mmp13 1 0.06 0.68 0.28
55 INT180964 PLG Positive_regulation of MMP13 1 0.24 0.45 0.25
56 INT168203 Binding of Mc1r and Msx1 1 0.19 0.64 0.25
57 INT275092 Twist1 Regulation of stm 1 0.00 0 0.25
58 INT243640 Binding of Twist1 and Stub1 1 0.08 0.34 0.24
59 INT235125 PDE2A Negative_regulation of Twist1 1 0.00 0.99 0.24
60 INT250873 Fgf8 Positive_regulation of GAG 1 0.55 0.48 0.23
61 INT182272 EDN1 Regulation of Gene_expression of MMP13 1 0.26 0.87 0.22
62 INT264526 PTGDS Negative_regulation of Gene_expression of MMP13 1 0.12 0.5 0.22
63 INT5874 Pitx1 Positive_regulation of Ina 1 0.17 0 0.21
64 INT5873 Pitx1 Negative_regulation of Ina 1 0.15 0 0.21
65 INT75057 Binding of POMC and Msx1 2 0.39 0.6 0.2
66 INT297544 Pou3f3 Regulation of Notch1 1 0.06 0.41 0.2
67 INT256629 Binding of Ptch1 and Shh 7 0.42 4.22 0.19
68 INT182271 EDN1 Positive_regulation of Localization of MMP13 1 0.27 0.47 0.19
69 INT318298 MECOM Negative_regulation of Binding of CD28 1 0.00 1.08 0.18
70 INT209581 Twist1 Positive_regulation of Gene_expression of VEGFA 6 0.06 7.86 0.16
71 INT148563 Ngf Positive_regulation of GNAS 1 0.06 0.07 0.16
72 INT219601 Pde4a Negative_regulation of Twist1 1 0.10 0 0.16
73 INT219598 Pde4a Negative_regulation of Gene_expression of Twist1 1 0.10 0 0.16
74 INT316052 Notch1 Regulation of Binding of Cd8a 1 0.01 0.86 0.15
75 INT316053 Notch1 Regulation of Binding of Cd4 1 0.02 0.86 0.15
76 INT208458 TWIST1 Positive_regulation of Localization of Bdnf 1 0.01 0.19 0.15
77 INT97547 KITLG Negative_regulation of Msx1 1 0.00 0.08 0.15
78 INT156833 Binding of MED1 and TRPV6 1 0.32 0 0.15
79 INT156837 Binding of CYP24A1 and MED1 1 0.47 0 0.15
80 INT316050 Binding of Notch1 and Regulation of Binding of Cd8a 1 0.01 0.86 0.15
81 INT97542 Pomc Negative_regulation of Msx1 1 0.13 0.07 0.15
82 INT316051 Binding of Notch1 and Regulation of Binding of Cd4 1 0.02 0.86 0.15
83 INT97545 Gtf3a Negative_regulation of Msx1 1 0.02 0.08 0.15
84 INT350711 Ifnb1 Negative_regulation of Gene_expression of DICER1 1 0.03 0.15 0.14
85 INT250863 Fgf8 Positive_regulation of Ptger2 1 0.03 0.19 0.14
86 INT323430 Binding of Vhl and Osr1 1 0.02 0.78 0.13
87 INT251115 Positive_regulation of Binding of AR and Ctnnb1 1 0.01 1.02 0.13
88 INT301414 Binding of Enpp2 and Twist1 1 0.08 1.26 0.13
89 INT264399 Binding of IL1B and MMP13 1 0.39 0.08 0.13
90 INT141881 Binding of MECOM and Tnfrsf1a 1 0.00 1.17 0.13
91 INT323434 Osr1 Regulation of Hif1a 1 0.01 0.79 0.13
92 INT323435 Binding of Osr1 and Gtf3a 1 0.00 0.78 0.13
93 INT323433 Osr1 Regulation of Protein_catabolism of Hif1a 1 0.01 0.8 0.13
94 INT264397 MMP9 Regulation of Positive_regulation of MMP13 1 0.20 0.06 0.12
95 INT264389 MMP14 Regulation of Positive_regulation of MMP13 1 0.31 0.06 0.12
96 INT214150 Binding of Mc3r and Msx1 1 0.03 0.5 0.12
97 INT264381 MMP3 Regulation of Positive_regulation of MMP13 1 0.21 0.06 0.12
98 INT323886 BMI1 Regulation of Gene_expression of MMP13 1 0.01 1.13 0.12
99 INT243642 Binding of Nfatc1 and Twist1 1 0.08 0.23 0.12
100 INT251114 Binding of AR and Ctnnb1 1 0.01 1 0.12
101 INT250866 Binding of Fgfr4 and Fgf8 1 0.12 0.35 0.11
102 INT255811 Binding of GNAS and MAPT 1 0.00 0.67 0.11
103 INT214152 Binding of Mc4r and Msx1 1 0.03 0.24 0.11
104 INT323882 Binding of BMI1 and MMP13 1 0.01 1.26 0.11
105 INT297546 Neurod1 Regulation of Notch1 1 0.05 0.2 0.1
106 INT302287 Twist1 Positive_regulation of Positive_regulation of PTGER2 1 0.03 1.16 0.1
107 INT302288 Twist1 Positive_regulation of PTGER2 1 0.03 1.16 0.1
108 INT215245 Binding of Myo1f and Chd7 1 0.00 0.64 0.1
109 INT250860 Fgf8 Regulation of Localization of Ptger2 1 0.02 0.13 0.1
110 INT250862 Fgf8 Regulation of Localization of Mmp3 1 0.13 0.13 0.1
111 INT250859 Fgf8 Negative_regulation of Gene_expression of Mmp3 1 0.09 0.12 0.09
112 INT250872 Fgf8 Positive_regulation of Mmp3 1 0.11 0.12 0.09
113 INT278217 Binding of Ciita and Notch1 1 0.41 0.22 0.09
114 INT214168 Msx1 Positive_regulation of Gene_expression of DST 1 0.00 0.13 0.09
115 INT255289 Snap25 Regulation of Gene_expression of Gnas 1 0.00 0 0.09
116 INT340505 Binding of Twist1 and Mgat4b 1 0.01 0.45 0.08
117 INT284303 Mir155 Negative_regulation of Gnas 1 0.00 0.49 0.08
118 INT234222 PSEN1 Regulation of Gene_expression of NOTCH1 1 0.03 0 0.08
119 INT270464 Binding of Shh and Smo 1 0.07 1.3 0.08
120 INT350909 Binding of Pcsk4 and Twist1 1 0.02 1.91 0.08
121 INT288374 Binding of MLANA and Msx1 1 0.09 0 0.08
122 INT290906 Shh Positive_regulation of Egfr 1 0.23 0 0.08
123 INT350908 Binding of Bcl2 and Twist1 1 0.04 1.9 0.08
124 INT322560 Binding of TNFSF10 and DICER1 1 0.07 1.76 0.07
125 INT273372 IL6 Regulation of Regulation of TWIST1 1 0.10 0.1 0.07
126 INT273366 IL6 Regulation of TWIST1 1 0.06 0.1 0.07
127 INT84751 Binding of HRAS and TWIST1 1 0.29 2.6 0.07
128 INT297246 Binding of Notch1 and Ncstn 1 0.04 0.32 0.07
129 INT298349 HES3 Positive_regulation of Shh 1 0.12 0.14 0.07
130 INT327871 Binding of Notch1 and Postn 1 0.38 1.42 0.07
131 INT138133 Nfkb1 Regulation of Positive_regulation of Mmp13 1 0.00 0.31 0.07
132 INT297244 Regulation of Binding of Notch1 and Ncstn 1 0.05 0.32 0.07
133 INT290905 Gene_expression of Shh Positive_regulation of Gene_expression of Angpt1 1 0.14 0 0.06
134 INT349886 Negative_regulation of Binding of Pcyt1a and Twist1 1 0.02 1.21 0.06
135 INT262214 Binding of Msx2 and Nr1i2 1 0.19 0.55 0.06
136 INT189557 Binding of NOTCH1 and ROBO4 1 0.01 0.22 0.06
137 INT225490 Med1 Positive_regulation of Ppara 1 0.12 0.26 0.06
138 INT243637 Il12a Positive_regulation of Transcription of Twist1 1 0.18 0.12 0.06
139 INT349887 Binding of Pcyt1a and Twist1 1 0.02 1.21 0.06
140 INT262173 Binding of Msx2 and Ep300 1 0.07 0.55 0.06
141 INT282552 POU5F1 Positive_regulation of FGF4 1 0.29 0.29 0.05
142 INT323878 Binding of LEP and MMP13 1 0.17 0.77 0.05
143 INT250865 Binding of Fgf8 and Fgfr3 1 0.18 0.3 0.05
144 INT273353 Pde4d Regulation of Gene_expression of Twist1 1 0.26 0.25 0.05
145 INT214146 Msx1 Positive_regulation of Gene_expression of Nucb2 1 0.05 0.19 0.05
146 INT250855 Binding of Fgfr2 and Fgf8 1 0.12 0.3 0.05
147 INT243633 Il23a Positive_regulation of Gene_expression of Twist1 1 0.14 0.11 0.05
148 INT210261 Bmp4 Regulation of Gene_expression of Tff3 1 0.64 0 0.05
149 INT310306 Tlr4 Regulation of Gene_expression of Chd7 1 0.01 0.25 0.04
150 INT220239 IL1B Positive_regulation of MMP13 1 0.23 0 0.04
151 INT233849 Twist1 Positive_regulation of Snai2 1 0.07 0.58 0.04
152 INT180956 PLG Regulation of Positive_regulation of MMP13 1 0.32 0.38 0.04
153 INT261393 Binding of Nsdhl and Med1 1 0.02 1 0.04
154 INT233852 Twist1 Positive_regulation of Snai1 1 0.02 0.58 0.04
155 INT349314 Binding of Notch1 and Notch3 1 0.11 0.67 0.04
156 INT275090 Twist1 Positive_regulation of Gene_expression of Pde5a 1 0.02 0.62 0.04
157 INT180957 Binding of PLG and Regulation of Positive_regulation of MMP13 1 0.14 0.38 0.04
158 INT213563 Binding of Ctnnd2 and Shh 1 0.27 0.09 0.04
159 INT233851 Twist1 Positive_regulation of Zeb1 1 0.06 0.58 0.04
160 INT275095 Twist1 Positive_regulation of Pde5a 1 0.03 0.62 0.04
161 INT270459 Binding of Shh and Gli1 1 0.02 0.65 0.04
162 INT233854 Twist1 Positive_regulation of Itk 1 0.03 0.58 0.04
163 INT264393 MMP1 Positive_regulation of Gene_expression of MMP13 1 0.29 0.14 0.04
164 INT352014 Shh Positive_regulation of Gene_expression of Pax1 1 0.29 0.07 0.03
165 INT220909 GNS Negative_regulation of Gene_expression of MMP13 1 0.00 0 0.03
166 INT243636 Stat1 Positive_regulation of Gene_expression of Twist1 1 0.46 0.05 0.03
167 INT301413 Positive_regulation of Binding of Enpp2 and Twist1 1 0.11 0.18 0.03
168 INT347165 Binding of NOTCH1 and PAX5 1 0.05 0.86 0.03
169 INT311655 Shh Positive_regulation of Gene_expression of Fgf8 1 0.31 0.18 0.03
170 INT301415 Positive_regulation of Binding of Twist1 and IL19 1 0.11 0.18 0.03
171 INT270462 Shh Positive_regulation of Ccnd1 1 0.10 0.6 0.03
172 INT327876 Postn Regulation of Gene_expression of Notch1 1 0.56 0.92 0.03
173 INT347163 NOTCH1 Positive_regulation of MSC 1 0.03 0.85 0.03
174 INT213559 Binding of Egf and Shh 1 0.17 0.07 0.03
175 INT301416 Binding of Twist1 and IL19 1 0.08 0.18 0.03
176 INT301408 Positive_regulation of Binding of Enpp1 and Twist1 1 0.06 0.18 0.03
177 INT347164 NOTCH1 Negative_regulation of Gene_expression of EBF1 1 0.03 0.85 0.03
178 INT220915 GNS Negative_regulation of MMP13 1 0.00 0 0.03
179 INT301406 Binding of Enpp1 and Twist1 1 0.04 0.18 0.03
180 INT235800 Twist1 Positive_regulation of VEGFA 1 0.02 0.62 0.03
181 INT258529 Binding of JAG1 and NOTCH1 3 0.06 2.44 0
182 INT258528 Binding of NOTCH1 and DLL1 2 0.07 1.6 0
183 INT225585 Regulation of Binding of Med1 and Tpr 1 0.00 0.07 0
184 INT291330 Binding of ENO1 and NOTCH1 1 0.03 1.33 0
185 INT264380 Binding of JUN and MMP13 1 0.05 0 0
186 INT193946 Binding of Notch1 and Positive_regulation of Psen1 1 0.03 0.06 0
187 INT290910 Pkm2 Negative_regulation of Shh 1 0.07 0.06 0
188 INT343744 mn Negative_regulation of Regulation of Wnt7a 1 0.01 0.1 0
189 INT209580 Twist1 Positive_regulation of Localization of VEGFA 1 0.05 0.53 0
190 INT280164 Twist1 Negative_regulation of Mod2 1 0.06 1.76 0
191 INT338694 Aff3 Positive_regulation of PGC 1 0.00 0.33 0
192 INT205963 GLI1 Positive_regulation of Negative_regulation of SHH 1 0.22 0.58 0
193 INT355603 Binding of CTNNA1 and Ctnnb1 1 0.00 1.07 0
194 INT314850 Shh Regulation of Atoh7 1 0.45 0.22 0
195 INT327870 Postn Positive_regulation of Gene_expression of Notch1 1 0.37 0.57 0
196 INT297245 Prnp Positive_regulation of Notch1 1 0.21 0.73 0
197 INT220818 Binding of Ctnnb1 and Myc 1 0.06 0.13 0
198 INT249538 Binding of BDNF and GNAS 1 0.08 0 0
199 INT290908 Regulation of Shh Positive_regulation of Ntn1 1 0.12 0 0
200 INT327873 Postn Regulation of Notch1 1 0.41 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for embryonic hindlimb morphogenesis. They are ordered first by their pain relevance and then by number of times they were reported in embryonic hindlimb morphogenesis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT129956 Gene_expression of MMP13 145 0.72 60.48 26.98
2 INT79395 Gene_expression of Twist1 193 0.77 100.06 26.34
3 INT123779 Positive_regulation of MMP13 42 0.65 24.3 12.45
4 INT10874 Negative_regulation of Twist1 89 0.50 36.84 11.32
5 INT62919 Regulation of Gnas 22 0.43 5.61 9.55
6 INT129962 Positive_regulation of Gene_expression of MMP13 41 0.65 20.74 8.54
7 INT43820 Positive_regulation of Twist1 75 0.59 42.15 8.47
8 INT39301 Gene_expression of Chd7 50 0.26 27.06 8.13
9 INT11258 Gene_expression of Gnas 58 0.58 21.6 6.33
10 INT67635 Negative_regulation of Gnas 29 0.04 11.4 6.32
11 INT250832 Gene_expression of Fgf8 1 0.77 13.36 6.2
12 INT329292 Gene_expression of Aff3 3 0.54 3.24 5.87
13 INT123726 Positive_regulation of Notch1 23 0.70 7.2 5.65
14 INT141146 Gene_expression of Mmp13 18 0.38 8.61 5.54
15 INT136664 Positive_regulation of Gene_expression of Twist1 49 0.69 25.91 5.41
16 INT94028 Regulation of Twist1 37 0.44 22.41 5.33
17 INT37912 Negative_regulation of Chd7 10 0.26 5.84 4.46
18 INT69217 Gene_expression of Notch1 20 0.78 7.8 4.41
19 INT98357 Binding of Gnas 11 0.41 1.87 4.35
20 INT129964 Negative_regulation of MMP13 23 0.55 6.48 4.21
21 INT32933 Gene_expression of GNAS 57 0.32 10.58 4.03
22 INT338681 Positive_regulation of Aff3 1 0.56 1.22 3.91
23 INT122323 Positive_regulation of NOTCH1 36 0.70 35.63 3.7
24 INT149614 Localization of MMP13 13 0.81 6.12 3.65
25 INT129960 Negative_regulation of Gene_expression of MMP13 19 0.53 7.17 3.55
26 INT67726 Gene_expression of Notch1 36 0.75 9.77 3.54
27 INT64766 Gene_expression of TWIST1 41 0.76 37.89 3.4
28 INT101567 Gene_expression of Ctnnb1 7 0.64 10.11 2.89
29 INT116540 Binding of Twist1 35 0.48 16.32 2.85
30 INT139872 Regulation of Notch1 14 0.45 7.69 2.82
31 INT190280 Gene_expression of DICER1 12 0.65 9.54 2.67
32 INT119025 Gene_expression of NOTCH1 46 0.75 31.32 2.64
33 INT77852 Binding of Chd7 8 0.31 4.1 2.51
34 INT32920 Gene_expression of Msx1 19 0.71 4.24 2.42
35 INT55090 Positive_regulation of Wnt7a 13 0.37 2.25 2.2
36 INT50057 Regulation of Notch1 3 0.39 0.87 2.14
37 INT120106 Negative_regulation of Mmp13 8 0.51 2.25 2.08
38 INT179311 Transcription of GNAS 2 0.10 0.67 2.08
39 INT108903 Negative_regulation of GNAS 7 0.57 1.58 2.04
40 INT145235 Protein_catabolism of Mmp13 3 0.89 2.46 2.03
41 INT48880 Positive_regulation of TWIST1 15 0.59 8.6 1.98
42 INT81641 Gene_expression of Ctnnb1 23 0.72 14.93 1.97
43 INT144973 Gene_expression of Shh 9 0.77 4.32 1.96
44 INT80798 Positive_regulation of Chd7 16 0.14 7.95 1.95
45 INT140036 Positive_regulation of Gene_expression of Notch1 6 0.61 2 1.86
46 INT52633 Negative_regulation of Notch1 4 0.42 2.99 1.84
47 INT102861 Phosphorylation of Twist1 6 0.70 0.86 1.81
48 INT208561 Gene_expression of Shh 51 0.78 9.57 1.77
49 INT182295 Regulation of MMP13 6 0.27 3.33 1.77
50 INT329296 Binding of Aff3 3 0.39 1.72 1.77
51 INT120088 Gene_expression of Bmp4 37 0.73 13.89 1.73
52 INT101707 Gene_expression of FGF4 9 0.78 3.99 1.73
53 INT250841 Positive_regulation of Gene_expression of Fgf8 1 0.69 3.8 1.72
54 INT329293 Negative_regulation of Aff3 2 0.34 1.22 1.69
55 INT123990 Positive_regulation of Ctnnb1 8 0.43 2.85 1.63
56 INT99391 Localization of Ctnnb1 7 0.80 5.84 1.61
57 INT180238 Regulation of Gene_expression of Twist1 13 0.61 4.87 1.59
58 INT141147 Negative_regulation of Gene_expression of Mmp13 5 0.12 1.37 1.59
59 INT6830 Positive_regulation of Notch1 20 0.55 7.91 1.57
60 INT163381 Transcription of Notch1 2 0.69 0.41 1.52
61 INT9953 Positive_regulation of Gnas 10 0.34 3.21 1.51
62 INT120111 Regulation of Mmp13 4 0.29 2.65 1.48
63 INT121347 Binding of GNAS 8 0.13 3.99 1.47
64 INT102860 Positive_regulation of Phosphorylation of Twist1 1 0.35 0.15 1.42
65 INT162308 Phosphorylation of GNAS 3 0.01 1.71 1.4
66 INT129963 Regulation of Gene_expression of MMP13 8 0.42 2.84 1.39
67 INT10873 Localization of Twist1 21 0.74 10.43 1.37
68 INT148740 Regulation of Gene_expression of Mmp13 1 0.03 2.58 1.37
69 INT219579 Negative_regulation of Gene_expression of Twist1 12 0.43 9.07 1.36
70 INT123778 Positive_regulation of Positive_regulation of MMP13 4 0.25 2.51 1.34
71 INT130098 Negative_regulation of NOTCH1 11 0.42 5.45 1.33
72 INT250850 Negative_regulation of Gene_expression of Fgf8 1 0.42 2.79 1.33
73 INT148562 Positive_regulation of GNAS 13 0.16 5.31 1.32
74 INT110784 Protein_catabolism of Notch1 8 0.21 2.32 1.31
75 INT243621 Transcription of Twist1 13 0.71 4.08 1.23
76 INT149295 Regulation of NOTCH1 10 0.13 4.26 1.22
77 INT120108 Transcription of Mmp13 3 0.51 0.22 1.22
78 INT99389 Negative_regulation of Ctnnb1 8 0.45 3.97 1.21
79 INT138726 Positive_regulation of Gene_expression of Msx1 5 0.53 1.73 1.2
80 INT108519 Binding of Lrp6 8 0.44 1.47 1.19
81 INT110780 Localization of Notch1 2 0.06 0.47 1.19
82 INT330526 Positive_regulation of Gene_expression of DICER1 5 0.30 3.34 1.18
83 INT149292 Localization of NOTCH1 7 0.54 6.11 1.14
84 INT253191 Positive_regulation of Gene_expression of Shh 2 0.66 2.57 1.14
85 INT123727 Negative_regulation of Notch1 6 0.21 1.22 1.11
86 INT250840 Negative_regulation of Fgf8 1 0.43 1.92 1.11
87 INT220926 Transcription of MMP13 12 0.67 3.03 1.09
88 INT338685 Regulation of Aff3 1 0.36 0.69 1.07
89 INT101570 Positive_regulation of Gene_expression of Ctnnb1 1 0.58 5.7 1.07
90 INT165530 Positive_regulation of Shh 4 0.69 1.21 1.05
91 INT277461 Positive_regulation of Gene_expression of Fgf8 1 0.24 0.47 1.05
92 INT127647 Regulation of Wnt7a 3 0.07 1.28 1.01
93 INT142813 Localization of RPGRIP1L 1 0.59 0.99 1.01
94 INT37914 Regulation of Negative_regulation of Chd7 1 0.12 0 1
95 INT141475 Negative_regulation of Gene_expression of TWIST1 5 0.41 3.94 0.97
96 INT130005 Protein_catabolism of MMP13 4 0.36 3.02 0.95
97 INT6833 Binding of Notch1 4 0.36 0.05 0.94
98 INT101566 Negative_regulation of Gene_expression of Ctnnb1 1 0.35 2.28 0.88
99 INT142122 Regulation of Gene_expression of Bmp4 5 0.43 2.69 0.86
100 INT224483 Regulation of Regulation of MMP13 2 0.15 1.16 0.86
101 INT338119 Negative_regulation of Transcription of Mmp13 1 0.09 0 0.86
102 INT210247 Positive_regulation of Bmp4 6 0.65 4.36 0.8
103 INT196325 Positive_regulation of Gene_expression of Chd7 7 0.14 4.28 0.76
104 INT215783 Localization of Gnas 1 0.12 1.64 0.76
105 INT208142 Gene_expression of PITX1 3 0.65 9.36 0.73
106 INT95617 Regulation of Msx1 2 0.56 1.05 0.73
107 INT140037 Positive_regulation of Positive_regulation of Notch1 2 0.22 1.34 0.69
108 INT75043 Binding of Msx1 6 0.35 2.36 0.65
109 INT28958 Negative_regulation of Wnt7a 3 0.45 0.49 0.65
110 INT120113 Positive_regulation of Mmp13 5 0.70 2.02 0.64
111 INT99390 Regulation of Ctnnb1 4 0.62 3.12 0.64
112 INT305480 Regulation of Protein_catabolism of Mmp13 1 0.29 0.73 0.64
113 INT96422 Gene_expression of Bmp4 18 0.69 3.26 0.63
114 INT243616 Positive_regulation of Transcription of Twist1 6 0.69 2.09 0.6
115 INT6831 Negative_regulation of Binding of Notch1 1 0.27 0 0.6
116 INT249551 Negative_regulation of Transcription of GNAS 1 0.06 0.16 0.6
117 INT136920 Positive_regulation of Gene_expression of NOTCH1 12 0.49 8.25 0.59
118 INT32921 Positive_regulation of Msx1 4 0.47 0.99 0.57
119 INT127648 Gene_expression of Wnt7a 2 0.13 1.11 0.56
120 INT110782 Negative_regulation of Localization of Notch1 1 0.03 0.33 0.56
121 INT149294 Regulation of Localization of NOTCH1 1 0.10 0.9 0.55
122 INT110785 Positive_regulation of Protein_catabolism of Notch1 1 0.05 0.33 0.55
123 INT76960 Negative_regulation of Ctnnb1 5 0.57 3.46 0.53
124 INT149297 Protein_catabolism of NOTCH1 2 0.15 0.87 0.51
125 INT100698 Regulation of Chd7 6 0.34 1.85 0.49
126 INT250845 Protein_catabolism of Fgf8 1 0.98 1.64 0.48
127 INT268007 Gene_expression of Fgf8 8 0.72 1.38 0.47
128 INT81645 Positive_regulation of Gene_expression of Ctnnb1 6 0.63 3.78 0.47
129 INT140436 Binding of TWIST1 5 0.39 2.34 0.47
130 INT81357 Regulation of Negative_regulation of Gnas 1 0.02 0.1 0.47
131 INT206484 Localization of Shh 2 0.75 1.14 0.46
132 INT158426 Binding of NOTCH1 10 0.36 7.95 0.45
133 INT142124 Binding of Bmp4 1 0.35 0.46 0.45
134 INT232798 Positive_regulation of Gene_expression of Shh 7 0.70 1.49 0.44
135 INT74864 Negative_regulation of Gene_expression of Chd7 1 0.08 0.34 0.44
136 INT338684 Localization of Aff3 1 0.61 0.2 0.44
137 INT338687 Negative_regulation of Localization of Aff3 1 0.34 0.2 0.44
138 INT277465 Regulation of Gene_expression of Fgf8 2 0.25 0.43 0.43
139 INT247307 Negative_regulation of Msx1 3 0.22 0.11 0.42
140 INT76958 Positive_regulation of Ctnnb1 14 0.64 5.48 0.41
141 INT180688 Transcription of Bmp4 3 0.58 0.35 0.41
142 INT284164 Localization of Chd7 3 0.25 1.32 0.41
143 INT180702 Positive_regulation of Transcription of Bmp4 3 0.42 0.35 0.41
144 INT95872 Localization of Ctnnb1 7 0.74 2.75 0.4
145 INT145045 Gene_expression of Med1 29 0.65 5.37 0.39
146 INT272502 Transcription of DICER1 3 0.08 2.14 0.39
147 INT343811 Positive_regulation of Transcription of DICER1 1 0.06 2.06 0.39
148 INT208559 Negative_regulation of Gene_expression of Shh 8 0.43 1.58 0.38
149 INT231199 Positive_regulation of Localization of Twist1 3 0.50 1.45 0.38
150 INT233917 Gene_expression of MED1 2 0.20 0.17 0.38
151 INT81644 Regulation of Ctnnb1 5 0.41 3.38 0.37
152 INT81643 Regulation of Gene_expression of Ctnnb1 3 0.57 1.5 0.37
153 INT173575 Binding of MMP13 2 0.35 0.79 0.36
154 INT343810 Binding of DICER1 1 0.05 1.88 0.35
155 INT330525 Positive_regulation of DICER1 2 0.17 1.34 0.34
156 INT250826 Transcription of Fgf8 1 0.71 0.71 0.34
157 INT220928 Positive_regulation of Transcription of MMP13 4 0.47 1.93 0.33
158 INT114473 Regulation of Gene_expression of FGF4 1 0.45 0.81 0.32
159 INT108324 Negative_regulation of Gene_expression of Ctnnb1 1 0.06 1.43 0.31
160 INT264548 Negative_regulation of Positive_regulation of MMP13 1 0.11 0.79 0.31
161 INT258685 Regulation of Gene_expression of Notch1 2 0.40 1.45 0.3
162 INT163891 Positive_regulation of Phosphorylation of MECOM 1 0.00 0.4 0.29
163 INT106734 Phosphorylation of MED1 4 0.74 1.65 0.28
164 INT163894 Phosphorylation of MECOM 1 0.00 0.4 0.28
165 INT114474 Binding of FGF4 1 0.32 0.66 0.28
166 INT335875 Regulation of Lrp6 1 0.57 0.43 0.27
167 INT214128 Negative_regulation of Gene_expression of Msx1 3 0.53 1.25 0.26
168 INT232795 Positive_regulation of Shh 2 0.70 3.68 0.26
169 INT121475 Regulation of Negative_regulation of Twist1 3 0.14 2.43 0.24
170 INT250836 Binding of Fgf8 3 0.35 0.66 0.24
171 INT151719 Negative_regulation of Positive_regulation of Ctnnb1 1 0.23 1.9 0.24
172 INT108902 Localization of GNAS 5 0.13 1.31 0.23
173 INT350691 Localization of DICER1 1 0.08 1.18 0.23
174 INT316049 Regulation of Regulation of Notch1 1 0.03 0.92 0.23
175 INT145234 Binding of Mmp13 1 0.37 0.43 0.23
176 INT183062 Gene_expression of SHH 12 0.65 5.28 0.21
177 INT130099 Negative_regulation of Positive_regulation of NOTCH1 4 0.43 2.56 0.21
178 INT157603 Positive_regulation of Gene_expression of Mmp13 3 0.16 0.91 0.21
179 INT142121 Positive_regulation of Gene_expression of Bmp4 3 0.47 7 0.21
180 INT250833 Localization of Fgf8 1 0.74 0.46 0.21
181 INT250842 Negative_regulation of Binding of Fgf8 1 0.43 0.33 0.21
182 INT297241 Positive_regulation of Positive_regulation of Notch1 2 0.40 1.02 0.2
183 INT134477 Negative_regulation of SHH 2 0.37 1.13 0.2
184 INT193945 Binding of Notch1 7 0.15 1.28 0.19
185 INT220938 Negative_regulation of Transcription of MMP13 2 0.40 0.32 0.19
186 INT208539 Positive_regulation of Gene_expression of Gnas 4 0.08 2.76 0.18
187 INT130096 Positive_regulation of Positive_regulation of NOTCH1 2 0.50 1.15 0.18
188 INT120085 Negative_regulation of Gene_expression of Bmp4 5 0.55 0.61 0.17
189 INT135054 Negative_regulation of Negative_regulation of Twist1 2 0.42 0.46 0.17
190 INT99392 Negative_regulation of Localization of Ctnnb1 2 0.59 1.43 0.17
191 INT151721 Negative_regulation of Localization of Ctnnb1 1 0.23 0.96 0.17
192 INT295673 Regulation of FGF4 1 0.05 0.83 0.17
193 INT325506 Positive_regulation of Localization of Ctnnb1 1 0.05 0.28 0.17
194 INT335861 Localization of Lrp6 1 0.69 0.54 0.17
195 INT232799 Regulation of Gene_expression of Shh 3 0.27 1.04 0.16
196 INT106730 Regulation of Phosphorylation of MED1 2 0.24 0.7 0.16
197 INT253177 Negative_regulation of Gene_expression of Shh 2 0.55 0.63 0.16
198 INT55089 Positive_regulation of Positive_regulation of Wnt7a 2 0.27 0.06 0.16
199 INT264448 Positive_regulation of Negative_regulation of MMP13 1 0.47 0.38 0.16
200 INT102354 Localization of TWIST1 3 0.75 0.17 0.15
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