GO:0035239

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Name tube morphogenesis
Categary Process
Go Slim No
Go Link GO:0035239
Unique Molecular Interactions 44
Total Molecular Interactions 54
Total Single Events 240
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for tube morphogenesis. They are ordered first by their pain relevance and then by number of times they were reported for tube morphogenesis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT89873 Pdyn Positive_regulation of Gene_expression of Gata4 1 0.23 0 1.29
2 INT89876 Pdyn Positive_regulation of Gata4 1 0.23 0 1.28
3 INT52955 Binding of Slc6a3 and Pdpn 1 0.17 1.11 1.22
4 INT73311 Binding of Oprm1 and Pdpn 1 0.08 0.71 1.06
5 INT165941 Bmp7 Positive_regulation of Penk 1 0.28 0.43 0.95
6 INT165942 Bmp7 Positive_regulation of Transcription of Pomc 1 0.29 0.43 0.95
7 INT165940 Bmp7 Positive_regulation of Pomc 1 0.29 0.43 0.95
8 INT101259 Gata6 Negative_regulation of Gene_expression of ALOX15 1 0.42 0.67 0.89
9 INT101258 Gene_expression of Gata6 Negative_regulation of Positive_regulation of ALOX15 1 0.42 0.65 0.87
10 INT109065 Pdyn Positive_regulation of Gene_expression of Gata4 1 0.00 0 0.58
11 INT129270 Binding of Wnt4 and Efs 1 0.00 0 0.55
12 INT52954 Binding of Pdpn and Flvcr2 1 0.05 0.42 0.41
13 INT118461 Bmp7 Positive_regulation of Th 1 0.31 0.06 0.25
14 INT213551 Proc Regulation of Bmp7 1 0.00 0.15 0.14
15 INT344314 PDPN Positive_regulation of Phosphorylation of MAPK8 1 0.35 0.67 0.13
16 INT129624 Bmp7 Positive_regulation of Gene_expression of Id2 1 0.26 0.31 0.08
17 INT129623 Bmp7 Positive_regulation of Gene_expression of Id3 1 0.37 0.31 0.08
18 INT129625 Id2 Positive_regulation of Gene_expression of Bmp7 1 0.24 0.31 0.08
19 INT129622 Id3 Positive_regulation of Gene_expression of Bmp7 1 0.25 0.31 0.08
20 INT129627 Bmp7 Positive_regulation of Id2 1 0.24 0.25 0.07
21 INT129626 Bmp7 Positive_regulation of Id3 1 0.25 0.25 0.07
22 INT201973 Bmp7 Positive_regulation of ap 1 0.00 0.18 0.06
23 INT118462 BMP7 Regulation of Bmp7 1 0.19 0 0.06
24 INT339110 ERBB2 Positive_regulation of GATA6 1 0.31 0.67 0.06
25 INT181814 Gsk3b Regulation of Gata4 1 0.06 0.37 0.05
26 INT344312 PDPN Positive_regulation of ITK 1 0.05 0.26 0.04
27 INT344317 PDPN Negative_regulation of VEGFA 1 0.08 0.67 0.03
28 INT344308 Positive_regulation of PDPN Negative_regulation of VEGFA 1 0.09 0.24 0.03
29 INT269944 Gata6 Regulation of Gene_expression of Foxj1 1 0.19 0 0
30 INT344315 MAPK8 Positive_regulation of Negative_regulation of PDPN 1 0.35 0.56 0
31 INT196038 Gene_expression of Bmp7 Positive_regulation of ALPP 1 0.03 0.1 0
32 INT344313 PDPN Positive_regulation of VEGFA 1 0.09 0.8 0
33 INT217780 MIR181A1 Regulation of GATA6 1 0.17 0.7 0
34 INT274434 Binding of Gata4 and Zfpm2 1 0.12 0.56 0
35 INT344319 MAPK8 Positive_regulation of PDPN 1 0.35 0.5 0
36 INT269941 Sox17 Regulation of Gene_expression of Foxa1 1 0.56 0 0
37 INT269917 Foxa1 Regulation of Gene_expression of Scgb1a1 1 0.24 0 0
38 INT196022 Bmp7 Regulation of Bmp4 1 0.06 0.06 0
39 INT344307 PDPN Negative_regulation of Gene_expression of VEGFA 1 0.08 0.36 0
40 INT344318 PDPN Positive_regulation of Positive_regulation of RHOA 1 0.11 0.92 0
41 INT269939 Foxa1 Regulation of Gene_expression of Foxj1 1 0.26 0 0
42 INT344316 VEGFA Positive_regulation of PDPN 1 0.09 0.4 0
43 INT344311 PDPN Positive_regulation of Negative_regulation of VEGFA 1 0.09 0.81 0
44 INT269956 Gata6 Regulation of Gene_expression of Scgb1a1 1 0.17 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for tube morphogenesis. They are ordered first by their pain relevance and then by number of times they were reported in tube morphogenesis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT52952 Binding of Pdpn 8 0.13 3.57 4.79
2 INT100295 Gene_expression of Bmp7 27 0.78 14.34 3.3
3 INT101246 Gene_expression of Gata6 6 0.68 3.03 2.68
4 INT101252 Negative_regulation of Gene_expression of Gata6 1 0.51 1.3 1.74
5 INT101244 Regulation of Gata6 3 0.40 1.52 1.7
6 INT23176 Gene_expression of Pdpn 6 0.75 4.06 1.65
7 INT89871 Gene_expression of Gata4 11 0.69 1.05 1.53
8 INT165538 Binding of Bmp7 5 0.37 1.87 1.39
9 INT109069 Transcription of Gata4 4 0.64 0.52 1.01
10 INT109070 Positive_regulation of Transcription of Gata4 1 0.03 0 1.01
11 INT101248 Negative_regulation of Gata6 1 0.37 0.83 0.85
12 INT101251 Negative_regulation of Positive_regulation of Gata6 1 0.38 0.83 0.85
13 INT101250 Positive_regulation of Gata6 1 0.41 0.83 0.84
14 INT101245 Transcription of Gata6 2 0.47 0.85 0.82
15 INT67252 Regulation of Pdpn 1 0.00 0.9 0.74
16 INT52951 Negative_regulation of Binding of Pdpn 1 0.16 0.63 0.66
17 INT100294 Positive_regulation of Gene_expression of Bmp7 8 0.46 5.41 0.61
18 INT89867 Negative_regulation of Gene_expression of Gata4 3 0.38 0.17 0.61
19 INT89868 Negative_regulation of Gata4 1 0.38 0 0.57
20 INT165537 Negative_regulation of Bmp7 2 0.43 0.55 0.52
21 INT129620 Regulation of Gene_expression of Bmp7 3 0.42 3.2 0.47
22 INT118460 Binding of Bmp7 3 0.46 1.3 0.4
23 INT117096 Gene_expression of Wnt4 2 0.67 4.68 0.38
24 INT109058 Positive_regulation of Gene_expression of Gata4 2 0.29 0 0.33
25 INT196032 Positive_regulation of Gene_expression of Bmp7 10 0.17 1.31 0.31
26 INT196024 Gene_expression of Bmp7 20 0.26 1.88 0.3
27 INT318437 Negative_regulation of Pdpn 1 0.47 0.87 0.25
28 INT152681 Gene_expression of PDPN 29 0.65 23.06 0.18
29 INT160121 Localization of PDPN 1 0.73 1.07 0.16
30 INT118459 Regulation of Bmp7 3 0.43 0.25 0.15
31 INT201968 Positive_regulation of Bmp7 2 0.43 1.11 0.14
32 INT355332 Localization of Bmp7 1 0.09 1.92 0.08
33 INT339183 Positive_regulation of GATA6 1 0.16 0.66 0.06
34 INT153022 Negative_regulation of Bmp7 1 0.01 0.27 0.06
35 INT344332 Positive_regulation of Gene_expression of PDPN 1 0.58 0.72 0.04
36 INT344330 Phosphorylation of PDPN 1 0.53 0.15 0.04
37 INT201965 Transcription of Bmp7 2 0.49 0.93 0.03
38 INT248540 Positive_regulation of Gata4 2 0.23 0.95 0.03
39 INT274404 Binding of Gata4 2 0.16 0.89 0
40 INT151839 Positive_regulation of Bmp7 2 0.27 0.24 0
41 INT344342 Binding of PDPN 1 0.31 0.74 0
42 INT217818 Gene_expression of GATA6 1 0.17 1.07 0
43 INT260766 Negative_regulation of Gene_expression of Bmp7 1 0.35 0 0
44 INT269871 Gene_expression of Foxa1 1 0.61 0 0
45 INT344340 Negative_regulation of Gene_expression of PDPN 1 0.36 1.53 0
46 INT201963 Positive_regulation of Binding of Bmp7 1 0.05 0 0
47 INT344339 Positive_regulation of PDPN 1 0.39 0.98 0
48 INT314125 Regulation of Transcription of Bmp7 1 0.25 0.88 0
49 INT205585 Regulation of Wnt4 1 0.45 0.7 0
50 INT314127 Regulation of Bmp7 1 0.25 0.88 0
51 INT205578 Negative_regulation of Wnt4 1 0.43 1.69 0
52 INT344335 Regulation of PDPN 1 0.38 0.41 0
53 INT344343 Transcription of PDPN 1 0.60 0.54 0
54 INT181811 Localization of Gata4 1 0.54 0.3 0
55 INT344337 Regulation of Negative_regulation of PDPN 1 0.23 0.05 0
56 INT328768 Positive_regulation of Gene_expression of Gata6 1 0.19 0.61 0
57 INT205581 Regulation of Negative_regulation of Wnt4 1 0.27 0.7 0
58 INT344334 Negative_regulation of PDPN 1 0.36 2.76 0
59 INT196028 Transcription of Bmp7 1 0.18 0 0
60 INT344333 Negative_regulation of Binding of PDPN 1 0.36 0.74 0
61 INT202389 Phosphorylation of Pdpn 1 0.61 0 0
62 INT196029 Localization of Bmp7 1 0.27 0.09 0
63 INT339154 Negative_regulation of GATA6 1 0.14 0.86 0
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