GO:0035249

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Name synaptic transmission, glutamatergic
Categary Process
Go Slim No
Go Link GO:0035249
Unique Molecular Interactions 442
Total Molecular Interactions 627
Total Single Events 5845
Pain Genes Associated 34

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for synaptic transmission, glutamatergic. They are ordered first by their pain relevance and then by number of times they were reported for synaptic transmission, glutamatergic. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT251146 Binding of Grin1 and Dlg2 1 0.36 1.95 3.16
2 INT101408 Binding of Grin1 and Olr1469 1 0.03 0.86 3.1
3 INT101407 Binding of Grin1 and Spr 1 0.14 0.86 3.09
4 INT102284 Binding of Grin1 and Grin2a 5 0.27 1.79 3.01
5 INT156381 Binding of Grin1 and Dlg4 1 0.39 0.86 2.9
6 INT170367 Binding of Grin1 and Grin2a 5 0.23 1.72 2.79
7 INT140347 Binding of ATP1A2 and Cacna1a 1 0.11 2.88 2.73
8 INT351444 Grin1 Positive_regulation of Gria2 1 0.22 1.5 2.64
9 INT317528 Ppp1r9b Regulation of Grin1 1 0.18 0.2 2.48
10 INT156799 Gria1 Regulation of Grm8 1 0.11 1.29 2.45
11 INT74840 Binding of Cacna1a and Cacna1a 5 0.00 4.24 2.36
12 INT317524 Binding of Camk2a and Grin1 1 0.17 0.06 2.21
13 INT122660 Binding of CACNA1A and DNAH8 2 0.28 2.68 2.08
14 INT156509 Il6 Regulation of Positive_regulation of Grin1 1 0.28 1.93 1.93
15 INT355251 Cacna1a Regulation of Gene_expression of Gabrg1 1 0.01 0.06 1.86
16 INT355249 Cacna1a Regulation of Gene_expression of Ltp 1 0.04 0.06 1.86
17 INT120732 Prkcg Positive_regulation of Phosphorylation of Grin1 2 0.48 1.04 1.81
18 INT272616 Positive_regulation of Binding of Grin1 and Grin2a 2 0.30 1.36 1.8
19 INT332773 Positive_regulation of Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.04 0.73 1.75
20 INT141907 F2r Regulation of Plat 1 0.46 0 1.59
21 INT105112 Plat Positive_regulation of JUN 1 0.01 1.55 1.58
22 INT355254 Ltp Regulation of Cacna1a 1 0.04 0 1.58
23 INT131575 Grin1 Negative_regulation of Positive_regulation of Ephb1 1 0.28 0.31 1.58
24 INT74843 Binding of Cacna1a and Ea2 3 0.13 3.29 1.55
25 INT148821 Binding of Oprm1 and Grin1 1 0.05 0.24 1.55
26 INT140329 Grin1 Negative_regulation of Ltp 1 0.04 0.64 1.46
27 INT158711 Cdk5 Positive_regulation of Phosphorylation of Trh 1 0.02 0 1.46
28 INT293200 Positive_regulation of Grin1 Positive_regulation of Phosphorylation of Grin2b 1 0.24 0.4 1.39
29 INT355250 Ltp Regulation of Positive_regulation of Cacna1a 1 0.04 0 1.39
30 INT108727 Binding of ATP1A2 and CACNA1A 2 0.34 1.97 1.37
31 INT122659 Binding of CACNA1A and SAR1B 1 0.06 1.38 1.35
32 INT355253 Ltp Positive_regulation of Cacna1a 1 0.05 0 1.34
33 INT317519 Grin1 Positive_regulation of Negative_regulation of Oprm1 1 0.14 0 1.31
34 INT355252 Binding of Cacna1a and Cnr1 1 0.04 0 1.31
35 INT18659 Plat Regulation of ZC3H12D 1 0.02 0.1 1.29
36 INT74841 Binding of Cacna1a and Ea2 2 0.01 2.33 1.27
37 INT197231 Grik1 Regulation of Gabrg1 1 0.19 0.13 1.22
38 INT110435 Positive_regulation of Grm8 Positive_regulation of Localization of Ca2 1 0.38 0 1.21
39 INT160653 Binding of P2rx1 and Ptgfr 1 0.28 0.66 1.14
40 INT317553 Binding of Car2 and Grin1 1 0.07 0 1.14
41 INT332776 FSCN1 Positive_regulation of Grin1 1 0.02 0.21 1.12
42 INT346986 Binding of SHC3 and PAG1 1 0.35 1.02 1.12
43 INT269191 Binding of Grin1 and Grin3a 2 0.32 1.05 1.09
44 INT317561 Binding of Grin1 and Oprm1 1 0.14 0.09 1.08
45 INT105113 Plat Positive_regulation of NFKB1 1 0.03 1.06 1.06
46 INT317531 Regulation of Binding of Grin1 and Mors1 1 0.08 0.06 1.05
47 INT317534 Regulation of Binding of Camk2a and Grin1 1 0.20 0.06 1.05
48 INT269199 Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.03 0.56 1.05
49 INT317535 Binding of Grin1 and Mors1 1 0.07 0.06 1.04
50 INT269194 Ceacam3 Positive_regulation of Phosphorylation of Grin1 1 0.09 0.55 1.02
51 INT131889 gr Regulation of Gene_expression of Grin1 1 0.02 0 1.01
52 INT186161 Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.11 1.05 1.01
53 INT317532 Grin1 Regulation of Negative_regulation of Oprm1 1 0.18 0.07 1
54 INT156510 Nfkb1 Regulation of Positive_regulation of Grin1 1 0.03 0.98 0.98
55 INT156508 Nfkb1 Regulation of Positive_regulation of Grin1 1 0.22 0.98 0.98
56 INT353372 Dio1 Positive_regulation of Grin1 1 0.16 0 0.98
57 INT156380 Regulation of Binding of Grin1 and Dlg4 1 0.29 0.32 0.97
58 INT108729 Binding of CACNA1A and Cacna1a 3 0.13 1.21 0.95
59 INT338893 TNFSF14 Positive_regulation of Gene_expression of Gria1 1 0.07 0.59 0.94
60 INT215584 P2rx1 Regulation of Localization of Gabrg1 1 0.01 0 0.92
61 INT52195 Sigmar1 Positive_regulation of Positive_regulation of Grin1 1 0.15 0 0.87
62 INT42865 Binding of Adrb2 and Man2a2 1 0.23 1.03 0.85
63 INT42864 Regulation of Binding of Adrb2 and Man2a2 1 0.28 1.03 0.85
64 INT127545 Gria1 Positive_regulation of Gene_expression of Gnptab 1 0.00 0.7 0.83
65 INT140280 Negative_regulation of Binding of Adora2a and Grina 1 0.21 0.64 0.82
66 INT98479 Lif Regulation of Gene_expression of Grin1 1 0.04 0.35 0.82
67 INT140281 Binding of Adora2a and Grina 1 0.19 0.64 0.82
68 INT144451 Napa Positive_regulation of Gene_expression of Nqo1 1 0.07 0.18 0.8
69 INT100559 Binding of Grin1 and LOC502940 1 0.13 0.61 0.8
70 INT54800 Grin1 Regulation of Gene_expression of Gh 1 0.01 0 0.79
71 INT144062 Grm8 Regulation of Localization of Pag1 1 0.21 0.63 0.79
72 INT214876 Ap3d1 Negative_regulation of Gria1 1 0.00 0.4 0.78
73 INT72017 Binding of Adora2a and Ptprg 2 0.07 0 0.77
74 INT351322 Nts Regulation of Localization of Napa 1 0.01 0.56 0.77
75 INT76498 Binding of Tacr1 and Adora2a 1 0.09 0 0.77
76 INT76499 Binding of Insr and Adora2a 1 0.08 0 0.76
77 INT252145 Binding of Napb and Snap25 9 0.19 0.85 0.75
78 INT82040 Adora2a Positive_regulation of Phosphorylation of Ppp1r1b 1 0.11 0 0.75
79 INT311525 Binding of Gria1 and Ltp 1 0.00 0.1 0.73
80 INT82041 Positive_regulation of Adora2a Positive_regulation of Phosphorylation of Ppp1r1b 1 0.12 0 0.72
81 INT186160 Negative_regulation of Grin2b Negative_regulation of Grin1 1 0.37 0.5 0.72
82 INT317547 Src Positive_regulation of Positive_regulation of Grin1 1 0.17 0 0.72
83 INT296290 Binding of Car1 and Grin1 1 0.11 0.32 0.72
84 INT197234 Grik1 Positive_regulation of Localization of Gabrg1 1 0.15 0.82 0.71
85 INT296295 Binding of Grin1 and Grin2b 1 0.16 0.31 0.71
86 INT134476 Cdk5 Regulation of Map2k1 1 0.69 0.88 0.71
87 INT195545 Rel Regulation of Gene_expression of Grm3 1 0.01 0.46 0.71
88 INT190984 Binding of Scn2a1 and Gria1 1 0.03 0.08 0.71
89 INT214410 Binding of ATP1A4 and CACNA1A 1 0.26 0.95 0.7
90 INT51433 Gria1 Positive_regulation of Eif3g 1 0.03 0 0.7
91 INT102344 Grin1 Regulation of Localization of C3orf52 1 0.00 0 0.68
92 INT114036 Binding of Grin1 and Psd 1 0.24 0.45 0.68
93 INT124257 Plat Positive_regulation of Jun 5 0.12 3.33 0.67
94 INT194857 Positive_regulation of Adora2a Positive_regulation of Gene_expression of Vegfa 1 0.23 0.74 0.67
95 INT102350 P2rx1 Negative_regulation of Localization of Il6 1 0.32 0 0.67
96 INT162224 Grin1 Positive_regulation of Gene_expression of Gria1 1 0.27 0.07 0.66
97 INT162223 Grin1 Positive_regulation of Localization of Gria2 1 0.23 0.07 0.66
98 INT128276 ecs Regulation of Transcription of Slc17a7 1 0.01 0.29 0.65
99 INT31416 Cacna1a Positive_regulation of Gene_expression of Gcg 1 0.03 0 0.65
100 INT197240 Grik2 Regulation of Gene_expression of Gabrg1 1 0.08 0.13 0.64
101 INT197238 Grik1 Regulation of Gene_expression of Gabrg1 1 0.17 0.13 0.64
102 INT239501 Binding of Adora2a and Mtx1 1 0.24 0.95 0.64
103 INT197236 Grik2 Regulation of Gabrg1 1 0.08 0.13 0.64
104 INT151783 Regulation of Binding of Calca and P2rx1 1 0.42 0.51 0.64
105 INT151778 Binding of Calca and P2rx1 1 0.35 0.5 0.64
106 INT236003 Binding of HTR1A and Grin1 1 0.01 0.7 0.63
107 INT128275 Slc17a7 Positive_regulation of Transcription of Slc17a6 1 0.39 0.27 0.63
108 INT186159 Grin2d Negative_regulation of Grin2b 1 0.21 0.82 0.62
109 INT197239 Grik1 Regulation of Localization of Gabrg1 1 0.10 0.56 0.61
110 INT201294 Negative_regulation of Grik1 Negative_regulation of Gabrg1 1 0.30 0 0.6
111 INT284790 Trpa1 Positive_regulation of Regulation of Napa 1 0.19 0 0.59
112 INT284784 Trpv1 Positive_regulation of Regulation of Napa 1 0.20 0 0.59
113 INT134528 Grin1 Regulation of Ngfr 1 0.03 0 0.57
114 INT134531 Gria1 Regulation of Ngfr 1 0.01 0 0.57
115 INT134530 Grin1 Regulation of Gria1 1 0.12 0 0.56
116 INT145718 Positive_regulation of Plat Positive_regulation of Bdnf 1 0.20 0 0.56
117 INT215644 Binding of Drd2 and Adora2a 1 0.03 0.23 0.55
118 INT312751 Phosphorylation of Gria1 Positive_regulation of GRIA1 1 0.18 0.22 0.55
119 INT259184 Binding of Gria2 and Gria1 2 0.26 0.28 0.54
120 INT263776 Grin1 Positive_regulation of Ltp 2 0.17 0.17 0.54
121 INT311521 Gnrhr Positive_regulation of Gene_expression of Gria1 1 0.00 0.54 0.54
122 INT311522 Gnrhr Positive_regulation of Transcription of Gria1 1 0.00 0.54 0.54
123 INT105111 Negative_regulation of Plat Positive_regulation of NFKB1 1 0.03 0.53 0.54
124 INT155406 Binding of Adrb2 and Ngf 1 0.05 0.39 0.53
125 INT349130 Phosphorylation of Gria1 Positive_regulation of Shisa9 1 0.00 0.49 0.52
126 INT3218 Adrb2 Positive_regulation of Localization of Ins1 1 0.10 0 0.52
127 INT66188 Binding of ADRB2 and CDSN 1 0.01 0 0.51
128 INT76068 Gal Positive_regulation of Grin1 1 0.34 0 0.51
129 INT259180 Pdpk1 Positive_regulation of Gene_expression of Gria1 1 0.02 0.4 0.49
130 INT250082 Positive_regulation of Ltp Positive_regulation of Positive_regulation of Grin1 1 0.03 0.08 0.49
131 INT259181 Phosphorylation of Pdpk1 Positive_regulation of Gene_expression of Gria1 1 0.02 0.4 0.49
132 INT354986 Cacna1a Regulation of Localization of Mpo 1 0.01 1.15 0.49
133 INT259183 Gria1 Positive_regulation of Phosphorylation of Gria2 1 0.30 0.39 0.49
134 INT152281 Binding of P2rx1 and Trpv1 1 0.15 0.42 0.49
135 INT283736 Tbs1 Positive_regulation of Grin1 1 0.04 0 0.48
136 INT273110 Bdnf Regulation of Positive_regulation of Gria1 1 0.43 0 0.47
137 INT273235 Binding of Cdk5 and Cdk5r1 1 0.24 6.06 0.46
138 INT35167 Adrb2 Positive_regulation of Trh 1 0.05 0 0.45
139 INT127392 Negative_regulation of Ephb1 Negative_regulation of Gene_expression of Grin1 1 0.08 0.71 0.45
140 INT341226 Gopc Regulation of Shc3 1 0.00 0.68 0.45
141 INT127397 Negative_regulation of Mdk Negative_regulation of Gene_expression of Grin1 1 0.01 0.71 0.45
142 INT250083 Positive_regulation of Ltp Positive_regulation of Grin1 1 0.03 0 0.45
143 INT354981 Cacna1a Negative_regulation of Gene_expression of Nos2 1 0.01 0.99 0.45
144 INT151782 Phosphorylation of Creb1 Positive_regulation of Gene_expression of P2rx1 1 0.41 0.07 0.44
145 INT151781 Calca Positive_regulation of Gene_expression of P2rx1 1 0.50 0.07 0.44
146 INT291963 Phex Negative_regulation of Gene_expression of Grin1 1 0.06 0.81 0.43
147 INT169859 P2rx7 Regulation of Gene_expression of Grin1 1 0.17 0 0.43
148 INT63372 Grin1 Regulation of Localization of Abat 1 0.20 0 0.43
149 INT155752 Binding of CACNA1A and ATCAY 1 0.04 0.86 0.42
150 INT217034 P2RX1 Regulation of Gene_expression of Ik 1 0.00 0.34 0.42
151 INT86069 Positive_regulation of Gria1 Positive_regulation of Gene_expression of Fos 1 0.11 0.3 0.42
152 INT127543 Gria1 Positive_regulation of Gene_expression of Cryge 1 0.00 0.35 0.42
153 INT74713 Binding of Gria1 and Olr1868 1 0.00 0 0.42
154 INT89666 Binding of Adora2a and Drd2 1 0.54 0.4 0.42
155 INT127546 Gria1 Positive_regulation of Gene_expression of Kcnab3 1 0.02 0.35 0.42
156 INT92744 Binding of ADRB2 and NF2 1 0.00 0.1 0.41
157 INT139654 Ntf3 Regulation of Gene_expression of Grin1 1 0.56 0.11 0.41
158 INT132730 Plat Positive_regulation of Il6 1 0.08 0.76 0.41
159 INT132729 Plat Positive_regulation of Il1b 1 0.09 0.76 0.41
160 INT124260 Plat Positive_regulation of Mapk1 1 0.14 0.81 0.41
161 INT231304 Prnp Negative_regulation of Grin2d 2 0.38 0.5 0.4
162 INT223474 Binding of Grik1 and P2rx3 1 0.03 0.36 0.4
163 INT354984 Binding of Cacna1a and Tnf 1 0.01 0.83 0.4
164 INT302871 Negative_regulation of Adora2a Positive_regulation of Phosphorylation of Th 1 0.26 0.12 0.4
165 INT296300 Binding of Grin1 and Kcnip3 1 0.18 0 0.4
166 INT131180 Binding of Grin1 and Oprd1 1 0.24 0 0.39
167 INT255283 Regulation of Binding of Napb and Snap25 1 0.24 0 0.39
168 INT158355 Cacna1a Regulation of Alox5 1 0.01 0.7 0.37
169 INT148515 Binding of Penk and Slc17a7 1 0.21 0 0.36
170 INT121757 Grin1 Regulation of Gene_expression of Fos 1 0.44 0.44 0.35
171 INT13374 Binding of Grin1 and Ltp 1 0.20 0 0.35
172 INT121758 Grin1 Regulation of Positive_regulation of Fos 1 0.44 0.44 0.35
173 INT117789 Binding of CALCA and Slc17a7 1 0.09 0 0.35
174 INT249406 Binding of Napa and Dcaf12l2 1 0.01 0.1 0.35
175 INT239503 Binding of Adora2a and Aes 1 0.24 0.85 0.35
176 INT284788 Napa Positive_regulation of Trpv1 1 0.31 0 0.35
177 INT273234 Negative_regulation of Cdk5 Positive_regulation of Ptprs 1 0.14 1.26 0.34
178 INT354985 Cacna1a Regulation of Nos2 1 0.01 0.73 0.34
179 INT354982 Cacna1a Regulation of Tnf 1 0.00 0.73 0.34
180 INT115162 Adora2a Regulation of Gene_expression of Jun 1 0.49 0.36 0.34
181 INT101551 Binding of CACNA1A and CACNA1F 1 0.07 1.51 0.33
182 INT115161 Adora2a Regulation of Gene_expression of Cpe 1 0.04 0.36 0.33
183 INT93896 Plat Positive_regulation of Gtf3a 1 0.00 0.51 0.32
184 INT263974 Binding of ADRB2 and NR4A3 1 0.01 0.5 0.32
185 INT263978 Binding of ADRB2 and TNFAIP3 1 0.01 0.5 0.32
186 INT16382 Binding of Grin1 and Gnmt 1 0.04 0.17 0.32
187 INT263979 Binding of ADRB2 and ATF3 1 0.01 0.5 0.32
188 INT124259 Negative_regulation of Plat Positive_regulation of Jun 4 0.11 1.74 0.31
189 INT142286 Binding of PLG and Plat 2 0.52 0.7 0.31
190 INT231306 Prnp Regulation of Grin1 1 0.60 0.35 0.31
191 INT196883 Prkca Regulation of P2rx1 1 0.05 0.45 0.31
192 INT151258 Binding of Cacna1a and FCMTE1 1 0.00 0.57 0.3
193 INT254122 Adora2a Regulation of Aliq1 1 0.01 0.85 0.3
194 INT255292 Regulation of Binding of Napb and Vamp2 1 0.07 0 0.3
195 INT317571 Grin1 Regulation of Trpv1 1 0.00 0 0.29
196 INT317562 Binding of Grin1 and Gnptab 1 0.00 0 0.29
197 INT258857 Binding of P2rx1 and P2ry2 1 0.22 0.81 0.29
198 INT255286 Binding of Napb and Vamp2 1 0.09 0 0.29
199 INT298995 Il18 Positive_regulation of Gene_expression of Cdk5 1 0.12 1.65 0.29
200 INT299008 Il18 Positive_regulation of Transcription of Cdk5 1 0.12 1.65 0.29

Single Events

The table below shows the top 100 pain related interactions that have been reported for synaptic transmission, glutamatergic. They are ordered first by their pain relevance and then by number of times they were reported in synaptic transmission, glutamatergic. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT49134 Gene_expression of Grin1 270 0.78 84.78 148.61
2 INT90910 Phosphorylation of Grin1 150 0.82 68.23 139.24
3 INT7341 Positive_regulation of Grin1 169 0.70 65.86 118.38
4 INT29708 Gene_expression of Gria1 177 0.78 56.36 77.37
5 INT90911 Positive_regulation of Phosphorylation of Grin1 62 0.70 27.45 59.26
6 INT7340 Regulation of Grin1 87 0.62 30.37 57.93
7 INT8071 Positive_regulation of Gria1 102 0.70 26.61 53.37
8 INT4957 Negative_regulation of Grin1 87 0.59 24.51 53.21
9 INT57021 Positive_regulation of Gene_expression of Grin1 62 0.70 24.77 47.31
10 INT66331 Gene_expression of Cacna1a 101 0.78 49.58 46.32
11 INT92517 Gene_expression of Grin1 105 0.78 29.53 39.43
12 INT26698 Positive_regulation of Cacna1a 37 0.67 26.33 39.1
13 INT11246 Binding of Grin1 65 0.48 14.53 36.93
14 INT64436 Gene_expression of P2rx1 93 0.78 32.69 36.12
15 INT52194 Positive_regulation of Grin1 83 0.69 25.09 34.76
16 INT57024 Regulation of Gene_expression of Grin1 32 0.62 9.77 32.6
17 INT114173 Phosphorylation of Gria1 27 0.82 33.73 31.24
18 INT49001 Regulation of Gria1 51 0.56 18.28 31.22
19 INT70776 Positive_regulation of P2rx1 62 0.62 32.55 30.75
20 INT106540 Negative_regulation of Phosphorylation of Grin1 15 0.58 9.32 29.13
21 INT80470 Negative_regulation of Gene_expression of Grin1 33 0.59 10.22 27.15
22 INT32794 Gene_expression of Grin2d 81 0.68 20.87 26.99
23 INT41487 Negative_regulation of Cacna1a 16 0.57 9.42 25.2
24 INT48536 Positive_regulation of Grm8 46 0.61 14.31 23.56
25 INT49623 Negative_regulation of Gria1 39 0.59 12.4 21.59
26 INT124670 Gene_expression of Grik1 53 0.77 4.83 19.13
27 INT107930 Gene_expression of Slc17a7 39 0.78 6.53 18.86
28 INT50420 Transcription of Grin1 30 0.71 13.21 18.28
29 INT29709 Positive_regulation of Gene_expression of Gria1 36 0.69 9.43 17.83
30 INT63928 Negative_regulation of Grin1 51 0.56 11.81 17.57
31 INT31136 Binding of Cacna1a 28 0.45 30.76 17.35
32 INT16624 Localization of Grin1 38 0.79 8.46 17.15
33 INT88356 Negative_regulation of Positive_regulation of Grin1 16 0.58 4.72 16.58
34 INT197210 Positive_regulation of Grik1 24 0.69 3.15 16.24
35 INT114172 Positive_regulation of Phosphorylation of Gria1 8 0.63 15.73 14.99
36 INT74745 Gene_expression of Grm8 30 0.68 9.85 14.52
37 INT61864 Regulation of Gene_expression of Gria1 24 0.62 13.27 14.3
38 INT15042 Gene_expression of Adora2a 37 0.77 3.77 14.24
39 INT92513 Regulation of Grin1 26 0.59 9.12 13.94
40 INT82929 Gene_expression of Plat 58 0.78 26.96 13.85
41 INT108063 Gene_expression of Adora2a 29 0.78 13.11 13.78
42 INT7342 Positive_regulation of Positive_regulation of Grin1 18 0.50 9.22 13.76
43 INT90942 Regulation of P2rx1 31 0.61 16.61 13.69
44 INT49538 Binding of Gria1 22 0.47 2.66 13.35
45 INT119089 Regulation of Phosphorylation of Grin1 17 0.61 3.1 12.82
46 INT50227 Positive_regulation of Adora2a 32 0.50 5.17 12.75
47 INT109223 Negative_regulation of Cdk5 14 0.59 3.27 12.73
48 INT30101 Regulation of Cacna1a 25 0.45 14.38 12.43
49 INT112103 Binding of Grin1 28 0.48 4.21 12.08
50 INT72784 Positive_regulation of Adora2a 26 0.70 16.52 11.47
51 INT75765 Positive_regulation of Gene_expression of Cacna1a 17 0.70 17.51 10.91
52 INT8072 Localization of Gria1 17 0.75 2.62 10.04
53 INT15449 Positive_regulation of Plat 32 0.69 12.76 9.71
54 INT65390 Positive_regulation of Plat 30 0.70 23.31 9.31
55 INT101602 Positive_regulation of Cdk5 15 0.70 4.1 8.96
56 INT121987 Phosphorylation of Grin1 11 0.80 4.73 8.88
57 INT29411 Positive_regulation of ADRB2 13 0.65 5.42 8.78
58 INT48088 Regulation of Grm8 12 0.62 4.93 8.71
59 INT68267 Gene_expression of CACNA1A 22 0.75 11.39 8.65
60 INT70775 Positive_regulation of Positive_regulation of P2rx1 15 0.49 8.65 8.49
61 INT127555 Negative_regulation of Cdk5 59 0.59 50.2 8.45
62 INT23209 Binding of Adora2a 17 0.38 2.04 8.35
63 INT139930 Gene_expression of Slc17a7 35 0.75 6.22 8.33
64 INT157580 Phosphorylation of Cdk5 4 0.77 0.73 8.33
65 INT117642 Regulation of Gene_expression of Grin1 18 0.53 7.09 8.08
66 INT95172 Localization of P2rx1 14 0.78 6.77 7.81
67 INT54755 Negative_regulation of Adora2a 17 0.58 2.7 7.75
68 INT135113 Localization of Grin1 18 0.73 3.73 7.69
69 INT7883 Binding of ADRB2 18 0.47 5.49 7.37
70 INT110705 Positive_regulation of Positive_regulation of Grin1 11 0.69 4.7 7.33
71 INT90943 Negative_regulation of P2rx1 13 0.42 8.21 7.22
72 INT10513 Gene_expression of Plat 44 0.76 19.49 7.17
73 INT57023 Negative_regulation of Gene_expression of Gria1 20 0.58 6.92 7.17
74 INT114014 Positive_regulation of Gene_expression of P2rx1 13 0.69 7.77 7.15
75 INT91351 Gene_expression of P2rx1 28 0.75 5.89 6.78
76 INT197216 Localization of Grik1 9 0.80 0.39 6.78
77 INT120298 Negative_regulation of Phosphorylation of Gria1 6 0.57 8.99 6.68
78 INT124488 Positive_regulation of Gene_expression of Plat 14 0.70 5.46 6.52
79 INT2513 Binding of Napa 80 0.42 4.29 6.51
80 INT91821 Binding of Cacna1a 16 0.48 13.1 6.37
81 INT17262 Negative_regulation of Plat 17 0.59 15.14 6.36
82 INT71758 Gene_expression of P2RX1 40 0.75 9.01 6.14
83 INT127556 Positive_regulation of Cdk5 35 0.70 19.6 5.95
84 INT94927 Transcription of Gria1 12 0.69 3.14 5.94
85 INT124825 Transcription of Plat 8 0.70 3.15 5.68
86 INT1243 Regulation of ADRB2 16 0.54 1.84 5.66
87 INT101604 Regulation of Cdk5 10 0.61 2.2 5.53
88 INT135473 Negative_regulation of Gene_expression of Grin1 14 0.47 5.47 5.36
89 INT83014 Binding of Adora2a 13 0.48 5.57 5.33
90 INT107247 Regulation of Plat 10 0.44 7.21 5.14
91 INT129508 Localization of Cacna1a 7 0.74 6.47 5.13
92 INT13885 Positive_regulation of Adrb2 9 0.49 1.11 5.12
93 INT89664 Negative_regulation of Adora2a 11 0.59 7.81 5.07
94 INT71759 Positive_regulation of P2RX1 13 0.67 3.53 4.9
95 INT51468 Regulation of Adora2a 8 0.48 1.5 4.84
96 INT110796 Positive_regulation of Positive_regulation of Cacna1a 1 0.49 0.51 4.84
97 INT104668 Negative_regulation of Plat 27 0.49 17.18 4.83
98 INT197219 Positive_regulation of Gene_expression of Grik1 5 0.69 0.83 4.67
99 INT24930 Binding of Adrb2 6 0.26 4.18 4.44
100 INT197230 Regulation of Positive_regulation of Grik1 4 0.45 0 4.42
101 INT93035 Negative_regulation of Transcription of Grin1 6 0.41 2.29 4.39
102 INT111404 Regulation of Positive_regulation of Grin1 5 0.56 2.49 4.31
103 INT82731 Transcription of Cacna1a 5 0.56 3.41 4.27
104 INT144396 Positive_regulation of P2rx1 11 0.49 3.25 4.23
105 INT195522 Gene_expression of Grm3 12 0.24 2.32 4.13
106 INT92902 Negative_regulation of Positive_regulation of Gria1 6 0.57 1.06 4.1
107 INT115354 Regulation of Binding of Grin1 2 0.43 1.15 4.08
108 INT50228 Positive_regulation of Positive_regulation of Adora2a 8 0.39 0.1 4
109 INT148495 Regulation of Cdk5 6 0.58 5.42 3.95
110 INT484 Negative_regulation of ADRB2 13 0.59 2.85 3.94
111 INT95171 Binding of P2rx1 12 0.36 4.69 3.92
112 INT89516 Negative_regulation of Grm8 7 0.41 4.01 3.82
113 INT287526 Negative_regulation of Gene_expression of CACNA1A 1 0.42 4.25 3.81
114 INT92516 Positive_regulation of Gene_expression of Grin1 8 0.45 2.53 3.77
115 INT84593 Positive_regulation of Binding of Grin1 6 0.48 2.74 3.72
116 INT131969 Regulation of Grik1 6 0.61 0.57 3.69
117 INT101701 Regulation of Adora2a 8 0.45 2.3 3.63
118 INT6882 Binding of Adrb2 5 0.47 1.97 3.55
119 INT197207 Negative_regulation of Grik1 5 0.43 1.91 3.5
120 INT132888 Negative_regulation of Phosphorylation of Grin1 3 0.57 1.18 3.43
121 INT290831 Positive_regulation of Napb 1 0.07 7.65 3.41
122 INT16626 Positive_regulation of Adrb2 10 0.30 2.41 3.4
123 INT231293 Negative_regulation of Grin2d 4 0.45 3.95 3.38
124 INT102276 Gene_expression of Grin2d 10 0.71 4.74 3.37
125 INT53516 Binding of CACNA1A 9 0.47 6.86 3.36
126 INT94045 Regulation of Cacna1a 5 0.42 3.56 3.33
127 INT84564 Regulation of Positive_regulation of Gria1 2 0.33 1.86 3.3
128 INT51427 Positive_regulation of Positive_regulation of Gria1 11 0.45 1.33 3.28
129 INT115407 Transcription of Slc17a7 2 0.72 1.28 3.12
130 INT115301 Negative_regulation of Binding of Napa 16 0.33 0.6 3.11
131 INT10517 Localization of Plat 16 0.47 8.44 3.11
132 INT78317 Regulation of CACNA1A 8 0.62 7.68 3.08
133 INT132887 Positive_regulation of Phosphorylation of Grin1 3 0.49 1.73 3.08
134 INT85572 Gene_expression of Cacna1a 11 0.66 5.72 3.02
135 INT142940 Positive_regulation of Negative_regulation of Cacna1a 3 0.50 1.65 2.97
136 INT97218 Regulation of Gene_expression of Grm8 3 0.24 2.26 2.97
137 INT41474 Gene_expression of ADRB2 10 0.75 1.56 2.94
138 INT26833 Negative_regulation of P2rx1 9 0.41 1.5 2.89
139 INT124489 Regulation of Gene_expression of Plat 5 0.45 0.48 2.87
140 INT144955 Binding of Grm8 8 0.22 1.82 2.83
141 INT128268 Positive_regulation of Gene_expression of Slc17a7 4 0.70 1.34 2.78
142 INT33480 Gene_expression of Adrb2 4 0.66 1.96 2.77
143 INT10512 Positive_regulation of Gene_expression of Plat 8 0.46 1.4 2.69
144 INT115300 Negative_regulation of Napa 7 0.23 1 2.68
145 INT163206 Transcription of Grm3 2 0.45 2.03 2.68
146 INT355244 Negative_regulation of Negative_regulation of Cacna1a 1 0.04 0 2.67
147 INT196733 Gene_expression of Cdk5 25 0.76 18.25 2.64
148 INT138789 Gene_expression of Cdk5 6 0.76 5.19 2.62
149 INT131973 Positive_regulation of Transcription of Gria1 3 0.49 0.35 2.62
150 INT110735 Regulation of Positive_regulation of Grm8 3 0.40 1.19 2.62
151 INT101401 Positive_regulation of Transcription of Grin1 6 0.67 2.45 2.6
152 INT311515 Negative_regulation of Gene_expression of Grin2d 1 0.02 4.37 2.56
153 INT9374 Regulation of Plat 19 0.61 6.04 2.55
154 INT144956 Negative_regulation of Gene_expression of Grm8 7 0.29 2.53 2.5
155 INT231295 Positive_regulation of Grin2d 8 0.41 0.7 2.48
156 INT514 Gene_expression of Adrb2 3 0.53 0.23 2.46
157 INT114026 Transcription of Grin1 7 0.67 3.13 2.45
158 INT254118 Negative_regulation of Gene_expression of Adora2a 3 0.42 2.54 2.43
159 INT109559 Localization of Napa 16 0.61 1.3 2.42
160 INT124826 Positive_regulation of Transcription of Plat 3 0.68 0.33 2.38
161 INT114024 Positive_regulation of Transcription of Grin1 1 0.49 1.69 2.37
162 INT231297 Localization of Grin2d 8 0.71 1.25 2.36
163 INT148494 Binding of Cdk5 6 0.40 5.97 2.31
164 INT183167 Positive_regulation of Gene_expression of Adora2a 4 0.70 2.37 2.31
165 INT112905 Phosphorylation of Cdk5 15 0.82 2.78 2.3
166 INT311514 Positive_regulation of Gene_expression of Grin2d 8 0.35 2.89 2.26
167 INT161575 Localization of CACNA1A 4 0.75 5.28 2.26
168 INT3531 Regulation of Adrb2 7 0.44 1.48 2.25
169 INT10514 Negative_regulation of Gene_expression of Plat 8 0.47 6.22 2.24
170 INT121435 Negative_regulation of Gene_expression of P2rx1 3 0.43 1.82 2.21
171 INT70725 Negative_regulation of Binding of ADRB2 3 0.57 0.4 2.14
172 INT195525 Regulation of Gene_expression of Grm3 1 0.04 0.82 2.14
173 INT157579 Binding of Cdk5 3 0.35 0.47 2.13
174 INT129505 Regulation of Slc17a7 5 0.37 1.09 2.11
175 INT110795 Regulation of Positive_regulation of Cacna1a 2 0.26 0.65 2.07
176 INT57939 Negative_regulation of Gene_expression of Adora2a 4 0.36 0.15 2.02
177 INT190390 Binding of Napb 6 0.22 2.07 2.01
178 INT290830 Positive_regulation of Positive_regulation of Napb 1 0.07 4.23 2
179 INT215166 Binding of P2rx1 5 0.35 0.41 1.97
180 INT72785 Positive_regulation of Positive_regulation of Adora2a 2 0.10 1.34 1.96
181 INT128267 Positive_regulation of Transcription of Slc17a7 1 0.70 0.82 1.9
182 INT22021 Positive_regulation of Negative_regulation of Grin1 3 0.49 0.69 1.89
183 INT194847 Negative_regulation of Positive_regulation of Adora2a 3 0.32 4.52 1.88
184 INT148492 Positive_regulation of Binding of Cdk5 1 0.47 0.51 1.86
185 INT158710 Negative_regulation of Binding of Cdk5 1 0.40 0 1.84
186 INT161459 Negative_regulation of Napb 6 0.20 0.6 1.82
187 INT128269 Positive_regulation of Slc17a7 3 0.50 1.06 1.82
188 INT40832 Localization of ADRB2 5 0.73 2.21 1.81
189 INT111405 Negative_regulation of Regulation of Grin1 1 0.54 0.09 1.81
190 INT354979 Positive_regulation of Localization of Cacna1a 2 0.05 0.86 1.79
191 INT355239 Negative_regulation of Positive_regulation of Cacna1a 1 0.04 0 1.79
192 INT106984 Regulation of P2RX1 12 0.60 2.05 1.75
193 INT197209 Positive_regulation of Positive_regulation of Grik1 4 0.50 0.36 1.74
194 INT146948 Negative_regulation of Positive_regulation of P2rx1 2 0.34 2.23 1.74
195 INT128273 Regulation of Gene_expression of Slc17a7 3 0.62 0.82 1.72
196 INT138660 Positive_regulation of Regulation of Grin1 2 0.24 1.59 1.71
197 INT115299 Regulation of Napa 14 0.54 0.56 1.7
198 INT124667 Negative_regulation of Grik2 4 0.41 2.06 1.7
199 INT71327 Localization of Cacna1a 3 0.60 2.51 1.7
200 INT195535 Positive_regulation of Grm3 8 0.25 3.37 1.67
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