GO:0035253

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Name ciliary rootlet
Categary Component
Go Slim No
Go Link GO:0035253
Unique Molecular Interactions 205
Total Molecular Interactions 302
Total Single Events 3445
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for ciliary rootlet. They are ordered first by their pain relevance and then by number of times they were reported for ciliary rootlet. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT191618 Binding of App and Nf1 1 0.35 3.77 1.65
2 INT111076 Psen1 Regulation of Psenen 1 0.17 0.76 1.58
3 INT266406 Binding of APP and Ager 1 0.00 2.34 1.57
4 INT120205 Binding of App and Ern1 1 0.05 2.55 1.18
5 INT168529 APP Regulation of FSIP1 2 0.65 2.26 1.07
6 INT159996 Prkcg Regulation of Gene_expression of App 1 0.42 0.32 0.92
7 INT159993 App Regulation of Gene_expression of Bace1 1 0.46 0.32 0.92
8 INT159994 App Regulation of Gene_expression of Prkcg 1 0.42 0.32 0.92
9 INT167431 Binding of APP and MYO1C 1 0.23 1.38 0.83
10 INT107917 RETNLB Positive_regulation of Gene_expression of App 1 0.01 1.2 0.79
11 INT99818 IFNG Positive_regulation of Gene_expression of APP 1 0.04 0.82 0.7
12 INT2700 Binding of App and Cpe 1 0.00 0 0.63
13 INT333544 CTSB Regulation of Protein_catabolism of APP 1 0.01 0.53 0.62
14 INT118083 Aip Negative_regulation of Phosphorylation of APP 1 0.00 0.75 0.62
15 INT333543 CTSB Regulation of APP 1 0.01 0.53 0.62
16 INT84771 Positive_regulation of Binding of App and Pag1 1 0.17 0.9 0.62
17 INT120203 Binding of App and Il1 1 0.17 1.28 0.59
18 INT120204 Binding of App and Il1f5 1 0.09 1.28 0.59
19 INT84770 Binding of App and Pag1 1 0.13 0.89 0.57
20 INT167618 Rho Regulation of App 1 0.17 0.88 0.55
21 INT167620 Rock2 Regulation of App 1 0.13 0.87 0.55
22 INT118082 APP Positive_regulation of Casp3 1 0.00 0.5 0.54
23 INT204494 Binding of App and Fmr1 1 0.54 4.39 0.54
24 INT145260 Binding of CLU and App 1 0.00 0.74 0.46
25 INT167621 Psenen Positive_regulation of App 1 0.02 0.86 0.44
26 INT167617 Bace2 Positive_regulation of App 1 0.06 0.87 0.44
27 INT167619 Protein_catabolism of Ppp2cb Positive_regulation of App 1 0.00 0.88 0.44
28 INT191610 Binding of App and Drd3 1 0.20 0.7 0.42
29 INT247599 Tlr4 Positive_regulation of Gene_expression of App 1 0.17 0.39 0.42
30 INT139873 Negative_regulation of CTSB Negative_regulation of Gene_expression of App 1 0.00 0.8 0.41
31 INT261652 Binding of MAPK1 and PSEN1 1 0.22 1.25 0.41
32 INT139874 CTSB Negative_regulation of Gene_expression of App 1 0.00 0.8 0.41
33 INT79577 APP Negative_regulation of PENK 1 0.12 0.35 0.4
34 INT78121 Positive_regulation of Binding of App and 20S 1 0.23 0.61 0.4
35 INT78122 Binding of App and 20S 1 0.16 0.61 0.4
36 INT323967 Il6 Positive_regulation of Gene_expression of App 1 0.10 0.86 0.38
37 INT78854 APP Positive_regulation of Localization of IL6 1 0.14 0.79 0.37
38 INT124376 Prodh2 Positive_regulation of App 1 0.00 0.66 0.33
39 INT124379 Prodh2 Positive_regulation of Localization of App 1 0.00 0.66 0.33
40 INT308667 Binding of Chrm1 and Positive_regulation of Binding of App 1 0.04 1.14 0.32
41 INT147434 Psenen Positive_regulation of APP 1 0.01 0.58 0.32
42 INT68977 App Positive_regulation of Localization of Mmp9 1 0.05 0.38 0.3
43 INT135095 Negative_regulation of CTSB Negative_regulation of APP 1 0.00 0.74 0.3
44 INT319220 FSIP1 Regulation of APP 1 0.29 1.46 0.29
45 INT79592 Binding of APP and Reg1 1 0.01 0.16 0.27
46 INT145616 Binding of Fez1 and Kif5a 1 0.05 0.25 0.27
47 INT25946 Regulation of Binding of Penk and App 1 0.18 0.19 0.27
48 INT25944 Binding of Penk and App 1 0.15 0.19 0.27
49 INT356094 Binding of App and Tg 1 0.08 0.12 0.26
50 INT139980 Negative_regulation of CTSB Negative_regulation of Gene_expression of APP 1 0.15 0.7 0.26
51 INT139981 CTSB Negative_regulation of Gene_expression of APP 1 0.11 0.7 0.26
52 INT39010 App Negative_regulation of Gene_expression of Gnrh1 1 0.05 0.07 0.26
53 INT297547 Pou3f3 Regulation of Psen1 1 0.00 0.41 0.25
54 INT114244 Cpox Negative_regulation of Gene_expression of APP 1 0.00 0.7 0.25
55 INT191619 Binding of App and Flna 1 0.04 0.18 0.24
56 INT70082 Binding of APP and TGM1 1 0.00 1.22 0.22
57 INT319971 App Regulation of Enpp1 1 0.02 0.72 0.21
58 INT146687 Regulation of Binding of App and Aph1a 1 0.16 0.58 0.19
59 INT146686 Binding of App and Aph1a 1 0.14 0.58 0.19
60 INT25945 Plat Regulation of App 1 0.15 0.25 0.17
61 INT25947 Plat Regulation of Transcription of App 1 0.15 0.25 0.17
62 INT319974 App Negative_regulation of Enpp1 1 0.02 0.58 0.16
63 INT204478 Fmr1 Regulation of Gene_expression of App 1 0.50 1.44 0.16
64 INT201744 Ngf Regulation of Transcription of App 1 0.06 0.39 0.15
65 INT201728 Ntrk1 Regulation of Transcription of App 1 0.03 0.39 0.15
66 INT319972 App Negative_regulation of Gene_expression of Enpp1 1 0.02 1.87 0.15
67 INT286476 Binding of App and Itm2b 1 0.47 5.24 0.14
68 INT94763 PSEN2 Regulation of Positive_regulation of App 1 0.11 0.72 0.14
69 INT139849 Binding of App and Bace1 7 0.41 0.85 0.13
70 INT204489 Fmr1 Regulation of App 1 0.50 1.71 0.13
71 INT220622 App Positive_regulation of Rip 2 0.14 0.24 0.12
72 INT297543 Neurod1 Regulation of Psen1 1 0.00 0.2 0.12
73 INT308660 Binding of Ager and App 1 0.08 1.22 0.12
74 INT70084 Negative_regulation of Binding of APP and TGM1 1 0.00 0.61 0.11
75 INT70083 TGM1 Positive_regulation of Binding of APP 1 0.00 0.61 0.11
76 INT123101 Binding of APP and Ache 1 0.07 0.32 0.11
77 INT198525 Binding of Kif5b and Ranbp2 1 0.23 0 0.1
78 INT204477 Binding of App and Scn10a 1 0.17 0.36 0.1
79 INT139847 Binding of App and Bace2 1 0.03 0.16 0.1
80 INT139850 Binding of MBTPS1 and App 1 0.00 0.16 0.1
81 INT193963 App Regulation of Gene_expression of Ps 1 0.06 0.93 0.09
82 INT356112 Binding of App and Apba1 1 0.24 0.29 0.09
83 INT262701 App Positive_regulation of Aplp2 1 0.12 0.25 0.09
84 INT262705 App Positive_regulation of Aplp1 1 0.13 0.25 0.09
85 INT124036 Binding of App and Dnahc8 1 0.03 0.14 0.09
86 INT234222 PSEN1 Regulation of Gene_expression of NOTCH1 1 0.03 0 0.08
87 INT205135 Binding of APOE and APP 1 0.05 0.35 0.08
88 INT193959 Psen1 Regulation of App 1 0.40 0.58 0.08
89 INT204487 Positive_regulation of Fmr1 Regulation of Gene_expression of App 1 0.30 0.8 0.08
90 INT193954 Binding of App and Psen1 3 0.38 0.88 0.06
91 INT273288 Psen1 Regulation of Prdx2 1 0.01 0.7 0.06
92 INT198934 Binding of App and Lrp1b 2 0.27 1.62 0.05
93 INT288099 Binding of APP and App 1 0.01 1.04 0.05
94 INT356086 Negative_regulation of Binding of App and Lrp1b 1 0.30 1.42 0.05
95 INT356110 Binding of App and Slc5a7 1 0.02 0.25 0.05
96 INT193967 Binding of PSEN1 and Psen1 1 0.41 1.2 0.05
97 INT193970 Binding of PSEN1 and Psen2 1 0.36 2.06 0.05
98 INT236009 HIST2H2AA3 Positive_regulation of Protein_catabolism of APP 1 0.02 0.19 0.04
99 INT236015 HIST2H2AA3 Positive_regulation of Gene_expression of APP 1 0.02 0.95 0.04
100 INT162753 Binding of APP and Slc30a2 1 0.00 1.25 0.04
101 INT319973 App Regulation of Gene_expression of Mapk12 1 0.02 0.98 0.04
102 INT162754 Negative_regulation of Binding of APP and Slc30a2 1 0.00 1.26 0.04
103 INT356101 App Regulation of Negative_regulation of Psen1 1 0.23 0.31 0.04
104 INT198921 Binding of App and Lrp1 3 0.32 2.7 0.03
105 INT331477 PSEN2 Regulation of Gene_expression of Psen1 1 0.00 0.15 0.03
106 INT356102 Negative_regulation of Binding of App and Lrp1 1 0.32 0.71 0.03
107 INT237090 Binding of App and Bnip3l 1 0.18 1.66 0.03
108 INT354896 Binding of Psen2 and Fancd2 1 0.04 0.75 0.03
109 INT230137 OSBP Regulation of APP 1 0.59 0.15 0.03
110 INT356097 Binding of App and Apba3 1 0.12 0.12 0.03
111 INT331478 Psen1 Regulation of Gene_expression of PSEN2 1 0.00 0.15 0.03
112 INT270432 Lhb Positive_regulation of APP 1 0.03 0.51 0.03
113 INT356090 Binding of Apba2 and App 1 0.00 0.12 0.03
114 INT270431 Gnrh1 Positive_regulation of APP 1 0.06 0.51 0.03
115 INT220628 Gene_expression of Gga1 Positive_regulation of App 2 0.22 0 0
116 INT220625 Negative_regulation of Binding of App and Bace1 1 0.44 0.09 0
117 INT193946 Binding of Notch1 and Positive_regulation of Psen1 1 0.03 0.06 0
118 INT356108 App Positive_regulation of Positive_regulation of Lrp1 1 0.43 0.52 0
119 INT333770 Bace1 Regulation of Gene_expression of App 1 0.57 0 0
120 INT193962 Binding of Psen1 and Ncstn 1 0.13 0.08 0
121 INT334644 Binding of PSEN1 and TTN 1 0.01 0 0
122 INT204493 App Negative_regulation of Scn10a 1 0.20 0.74 0
123 INT350098 Gene_expression of PSEN2 Positive_regulation of Gene_expression of Hmox1 1 0.39 0 0
124 INT273289 Binding of Psen2 and Ryr2 1 0.27 4.53 0
125 INT236013 HIST2H2AA3 Regulation of Gene_expression of APP 1 0.01 0 0
126 INT204499 App Regulation of Fmr1 1 0.50 0.59 0
127 INT204492 Negative_regulation of Binding of App and Fmr1 1 0.42 0.28 0
128 INT356083 Binding of App and Notch1 1 0.02 0.2 0
129 INT356095 Lrp1 Positive_regulation of App 1 0.37 0.53 0
130 INT204502 Binding of App and RNPC3 1 0.01 0.09 0
131 INT356091 Lrp1 Positive_regulation of Positive_regulation of App 1 0.43 0.52 0
132 INT204481 App Negative_regulation of Positive_regulation of Scn10a 1 0.20 0.74 0
133 INT217398 Binding of Psen2 and Bace1 1 0.12 1.44 0
134 INT356100 Binding of Apbb1 and App 1 0.14 0.43 0
135 INT356087 Binding of App and Ncstn 1 0.17 0.07 0
136 INT230140 Gene_expression of OSBP Regulation of Localization of APP 1 0.30 0.06 0
137 INT193955 Binding of Psen1 and Psen2 1 0.37 1.64 0
138 INT193948 Binding of Psen1 and Notch1 1 0.02 0 0
139 INT198933 Binding of Apoe and App 1 0.33 0.19 0
140 INT286331 Binding of Psen1 and Ror1 1 0.27 0 0
141 INT198927 Lrp1 Regulation of App 1 0.14 0.42 0
142 INT193968 Binding of PSEN1 and Ps 1 0.07 0.66 0
143 INT204482 Fmr1 Negative_regulation of App 1 0.42 0.74 0
144 INT334643 Binding of APP and HM13 1 0.02 0 0
145 INT262712 Psen1 Regulation of Gene_expression of Bace1 1 0.22 0.07 0
146 INT356118 Binding of SORL1 and App 1 0.41 0.43 0
147 INT230146 Binding of APP and SORL1 1 0.20 0.17 0
148 INT356109 Rab6a Regulation of App 1 0.14 0.05 0
149 INT180123 Egfl7 Positive_regulation of App 1 0.02 0.07 0
150 INT217400 Binding of Psen1 and Bace1 1 0.17 1.43 0
151 INT286337 PSENEN Regulation of Psen1 1 0.07 0.37 0
152 INT193958 Binding of Pld1 and Psen1 1 0.17 0 0
153 INT356106 Gene_expression of Pld1 Positive_regulation of App 1 0.29 0.21 0
154 INT225629 APP Positive_regulation of Positive_regulation of nr 1 0.01 0.08 0
155 INT217396 Binding of Abca1 and App 1 0.26 0.83 0
156 INT262708 Bace1 Positive_regulation of Gene_expression of App 1 0.44 2.82 0
157 INT198915 Binding of App and Lrp8 1 0.24 0.17 0
158 INT193953 Binding of Bcl2l1 and Psen1 1 0.07 0.66 0
159 INT230139 OSBP Regulation of Phosphorylation of APP 1 0.50 0 0
160 INT193956 Binding of Psen1 and Rab6a 1 0.15 0 0
161 INT142955 Positive_regulation of Binding of APP and BACE1 1 0.48 0.5 0
162 INT262713 App Regulation of Transcription of Bace1 1 0.45 0.31 0
163 INT294428 PSEN2 Regulation of Gene_expression of Tp53 1 0.49 0.86 0
164 INT198925 Binding of App and Ldlr 1 0.14 0.15 0
165 INT294429 PSEN2 Negative_regulation of Tp53 1 0.46 1.03 0
166 INT193957 Binding of Bcl2l1 and Psen2 1 0.07 0.66 0
167 INT331479 Binding of PSEN2 and Psen1 1 0.00 0.07 0
168 INT333773 Bace1 Regulation of App 1 0.25 0 0
169 INT230143 OSBP Regulation of Gene_expression of APP 1 0.50 0.1 0
170 INT142954 Binding of APP and BACE1 1 0.37 0.5 0
171 INT204491 Ass1 Positive_regulation of App 1 0.01 0.43 0
172 INT234221 Negative_regulation of PSEN1 Negative_regulation of Gene_expression of APP 1 0.33 0.32 0
173 INT50104 Bche Regulation of Localization of App 1 0.43 0.2 0
174 INT356104 Positive_regulation of Binding of App and Lrp1 1 0.40 0.52 0
175 INT230151 OSBP Regulation of Localization of APP 1 0.50 0 0
176 INT220624 Eif1 Regulation of App 1 0.00 0.1 0
177 INT204496 App Positive_regulation of Scn10a 1 0.20 0.48 0
178 INT225627 APP Positive_regulation of nr 1 0.02 0.08 0
179 INT334645 Binding of PSEN1 and HM13 1 0.01 0 0
180 INT230149 Binding of APP and NOTCH2 1 0.32 0.32 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for ciliary rootlet. They are ordered first by their pain relevance and then by number of times they were reported in ciliary rootlet. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT65500 Gene_expression of App 605 0.78 429.94 98.31
2 INT29743 Negative_regulation of App 91 0.59 65.56 31.26
3 INT47712 Positive_regulation of App 135 0.69 101.38 28.94
4 INT89662 Positive_regulation of Gene_expression of App 169 0.70 133.36 25.62
5 INT44954 Gene_expression of APP 191 0.78 105.86 23.9
6 INT11625 Localization of App 98 0.78 55.46 20.86
7 INT16794 Binding of App 103 0.48 64.87 19.79
8 INT65502 Regulation of App 77 0.62 52.05 19.44
9 INT23657 Positive_regulation of APP 64 0.70 39.76 16.68
10 INT111073 Gene_expression of Psen1 167 0.76 78.65 15.83
11 INT54052 Gene_expression of App 33 0.78 25.08 14.7
12 INT29745 Binding of APP 47 0.48 26.49 12.4
13 INT107916 Protein_catabolism of App 114 1.00 66.71 12.38
14 INT65501 Regulation of Gene_expression of App 56 0.62 32.51 11.48
15 INT98789 Negative_regulation of Gene_expression of App 54 0.58 40.27 11.15
16 INT41569 Regulation of APP 32 0.62 17.15 9.4
17 INT91772 Gene_expression of PSEN1 115 0.75 38.12 8.48
18 INT56031 Positive_regulation of App 25 0.69 13.46 7.37
19 INT84932 Negative_regulation of APP 29 0.57 28.45 7.2
20 INT111069 Regulation of Psen1 19 0.44 7.78 5.87
21 INT60724 Gene_expression of Psen2 30 0.72 27 5.79
22 INT107173 Phosphorylation of App 20 0.82 12.64 5.3
23 INT99823 Positive_regulation of Gene_expression of APP 31 0.70 21.52 5.09
24 INT115816 Protein_catabolism of APP 35 0.99 20.14 5.06
25 INT131692 Negative_regulation of Localization of App 9 0.53 4.69 4.82
26 INT78116 Positive_regulation of Gene_expression of App 12 0.70 10.78 4.52
27 INT58003 Localization of APP 32 0.80 13.75 4.2
28 INT111067 Positive_regulation of Gene_expression of Psen1 32 0.68 21.2 4.19
29 INT99821 Negative_regulation of Gene_expression of APP 20 0.42 15.21 3.94
30 INT11627 Positive_regulation of Localization of App 14 0.62 6.27 3.64
31 INT99819 Negative_regulation of Positive_regulation of APP 6 0.58 4.41 3.64
32 INT70089 Negative_regulation of Binding of APP 7 0.59 6.45 3.44
33 INT211591 Negative_regulation of PSEN1 14 0.57 5.73 3.26
34 INT91761 Gene_expression of PSEN2 38 0.75 22.93 3.03
35 INT108773 Negative_regulation of Binding of App 10 0.42 7.26 2.96
36 INT193936 Positive_regulation of PSEN1 5 0.58 11.57 2.95
37 INT54055 Regulation of Gene_expression of App 7 0.62 4.04 2.93
38 INT178772 Transcription of App 17 0.70 10.79 2.79
39 INT147429 Negative_regulation of Positive_regulation of App 8 0.40 8.73 2.78
40 INT54054 Binding of App 4 0.48 10.89 2.78
41 INT163544 Binding of Psen1 40 0.36 15.28 2.42
42 INT162513 Regulation of Protein_catabolism of APP 5 0.51 1.79 2.36
43 INT11626 Regulation of Localization of App 4 0.45 1.51 2.34
44 INT56030 Regulation of App 8 0.62 4.06 2.32
45 INT124772 Regulation of Binding of App 6 0.45 4.92 2.09
46 INT39008 Localization of App 13 0.77 9.07 2.05
47 INT181507 Positive_regulation of Psen1 22 0.49 7.59 2.04
48 INT60723 Localization of Psen2 5 0.68 2.11 2.02
49 INT193939 Binding of PSEN1 10 0.36 6.16 1.93
50 INT142774 Regulation of Phosphorylation of App 1 0.59 2.27 1.93
51 INT121117 Regulation of Protein_catabolism of App 10 0.62 6.41 1.78
52 INT111070 Negative_regulation of Gene_expression of Psen1 17 0.42 9.47 1.77
53 INT107915 Regulation of Negative_regulation of App 6 0.45 4.47 1.76
54 INT133863 Positive_regulation of Protein_catabolism of App 12 0.59 7.53 1.52
55 INT282434 Regulation of Gene_expression of Psen1 9 0.50 2.85 1.52
56 INT58004 Positive_regulation of Localization of APP 5 0.46 2.1 1.5
57 INT25943 Transcription of App 5 0.53 1.79 1.44
58 INT78646 Regulation of Psen2 4 0.20 1.78 1.42
59 INT125796 Regulation of Gene_expression of APP 8 0.59 5.95 1.41
60 INT129700 Regulation of Positive_regulation of App 3 0.43 1.86 1.41
61 INT181509 Negative_regulation of Psen1 17 0.57 11.53 1.35
62 INT141529 Regulation of Positive_regulation of APP 3 0.44 0.31 1.34
63 INT103488 Positive_regulation of Localization of App 5 0.50 3.05 1.28
64 INT100137 Positive_regulation of Negative_regulation of App 2 0.41 1.26 1.16
65 INT135899 Regulation of Binding of APP 3 0.45 1.22 1.14
66 INT39009 Negative_regulation of App 6 0.38 3.37 1.07
67 INT78645 Negative_regulation of Gene_expression of Psen2 1 0.14 0.13 1.01
68 INT91771 Positive_regulation of Gene_expression of PSEN1 13 0.49 8.93 0.93
69 INT167607 Positive_regulation of Binding of App 8 0.50 2.97 0.86
70 INT162514 Positive_regulation of Regulation of APP 1 0.41 0.37 0.86
71 INT99375 Positive_regulation of Binding of APP 3 0.61 1.63 0.83
72 INT78647 Positive_regulation of Localization of Psen2 1 0.16 0.14 0.83
73 INT237406 Positive_regulation of Binding of Psen1 1 0.29 0 0.8
74 INT94756 Positive_regulation of PSEN2 8 0.49 4.59 0.77
75 INT118078 Phosphorylation of APP 10 0.79 2.5 0.76
76 INT286313 Transcription of Psen1 9 0.70 2.26 0.76
77 INT193849 Positive_regulation of Gene_expression of Psen2 5 0.44 4.92 0.76
78 INT99820 Negative_regulation of Localization of APP 2 0.37 0.75 0.76
79 INT78649 Binding of Psen2 7 0.36 5.9 0.73
80 INT78648 Regulation of Binding of Psen2 1 0.14 0.2 0.73
81 INT112208 Negative_regulation of Gene_expression of App 4 0.59 1.88 0.68
82 INT25942 Regulation of Transcription of App 3 0.27 0.95 0.68
83 INT141528 Regulation of Localization of APP 2 0.52 0.4 0.67
84 INT91765 Positive_regulation of Gene_expression of PSEN2 8 0.49 4.57 0.63
85 INT61147 Protein_catabolism of App 3 0.60 3.76 0.63
86 INT118077 Negative_regulation of Phosphorylation of APP 1 0.07 0.74 0.61
87 INT142112 Regulation of Regulation of App 3 0.39 2.46 0.59
88 INT225462 Positive_regulation of Positive_regulation of APP 3 0.44 1.41 0.55
89 INT217394 Regulation of Binding of PSEN1 1 0.44 1.58 0.53
90 INT78117 Positive_regulation of Positive_regulation of App 4 0.48 2.6 0.51
91 INT316041 Transcription of Psen2 1 0.64 1.1 0.45
92 INT167614 Positive_regulation of Protein_catabolism of App 1 0.30 0.88 0.44
93 INT234249 Regulation of PSEN1 6 0.37 2.21 0.43
94 INT234257 Regulation of Gene_expression of PSEN1 6 0.44 1.98 0.42
95 INT193856 Localization of Psen1 19 0.73 9.79 0.41
96 INT36396 Positive_regulation of Psen2 6 0.44 4.57 0.39
97 INT177773 Localization of PSEN1 4 0.73 0.89 0.36
98 INT261682 Positive_regulation of Positive_regulation of PSEN2 1 0.21 0.55 0.33
99 INT54056 Negative_regulation of Binding of App 2 0.37 0.99 0.32
100 INT178773 Positive_regulation of Regulation of App 2 0.49 1.01 0.32
101 INT178774 Positive_regulation of Transcription of App 2 0.49 1.17 0.31
102 INT224298 Negative_regulation of PSEN2 6 0.57 2.29 0.28
103 INT316045 Negative_regulation of Negative_regulation of Psen1 1 0.42 1.58 0.27
104 INT261676 Negative_regulation of Positive_regulation of PSEN1 1 0.36 1.59 0.25
105 INT172525 Localization of PSEN2 5 0.73 4.17 0.24
106 INT181508 Regulation of Regulation of Psen1 2 0.33 0.51 0.2
107 INT286317 Positive_regulation of Transcription of Psen1 1 0.37 0.32 0.17
108 INT180104 Positive_regulation of Phosphorylation of App 2 0.54 0.87 0.16
109 INT286326 Regulation of Transcription of App 3 0.45 0.26 0.15
110 INT336359 Positive_regulation of Phosphorylation of Psen1 1 0.33 0.4 0.13
111 INT69045 Negative_regulation of Positive_regulation of App 1 0.05 0.28 0.13
112 INT336361 Phosphorylation of Psen1 1 0.54 0.34 0.13
113 INT176595 Negative_regulation of Gene_expression of PSEN2 1 0.24 1.01 0.11
114 INT193841 Regulation of Gene_expression of Psen2 1 0.40 1.66 0.11
115 INT201694 Negative_regulation of Gene_expression of PSEN1 3 0.41 2.31 0.1
116 INT142958 Positive_regulation of Protein_catabolism of APP 3 0.55 2.04 0.1
117 INT273285 Negative_regulation of Localization of Psen1 1 0.36 0.99 0.09
118 INT109131 Regulation of PSEN2 3 0.44 0.55 0.08
119 INT39007 Negative_regulation of Localization of App 3 0.10 0.94 0.08
120 INT193862 Positive_regulation of Positive_regulation of Psen1 3 0.49 0.9 0.08
121 INT193872 Positive_regulation of Localization of Psen1 3 0.49 1.39 0.08
122 INT261678 Positive_regulation of Positive_regulation of PSEN1 1 0.42 0.62 0.08
123 INT193890 Regulation of Positive_regulation of Psen1 1 0.44 0.66 0.08
124 INT193938 Phosphorylation of PSEN1 5 0.79 1.6 0.07
125 INT176592 Transcription of PSEN2 5 0.33 0.41 0.05
126 INT193859 Negative_regulation of Binding of Psen1 3 0.42 1.85 0.05
127 INT331406 Negative_regulation of Regulation of Psen1 1 0.04 0.09 0.05
128 INT193865 Protein_catabolism of Psen1 10 0.97 0.37 0.04
129 INT180116 Negative_regulation of Transcription of App 1 0.38 0 0.04
130 INT182830 Negative_regulation of Protein_catabolism of APP 2 0.35 2.09 0.03
131 INT255657 Negative_regulation of Protein_catabolism of App 1 0.20 1.07 0.03
132 INT351386 Negative_regulation of Phosphorylation of App 1 0.42 0.82 0.03
133 INT224302 Negative_regulation of Transcription of PSEN2 3 0.26 0.08 0
134 INT50103 Regulation of Localization of App 2 0.26 0.2 0
135 INT234255 Transcription of APP 2 0.49 0.98 0
136 INT265229 Binding of PSEN2 2 0.16 1.37 0
137 INT286327 Regulation of Binding of Psen1 1 0.33 0.16 0
138 INT234250 Positive_regulation of Negative_regulation of PSEN1 1 0.41 0 0
139 INT286323 Negative_regulation of Protein_catabolism of App 1 0.11 0.54 0
140 INT193886 Regulation of Protein_catabolism of Psen1 1 0.44 0.06 0
141 INT193934 Positive_regulation of Binding of PSEN1 1 0.49 0.92 0
142 INT224297 Regulation of Transcription of PSEN2 1 0.20 0.06 0
143 INT331407 Negative_regulation of Transcription of Psen1 1 0.04 0.08 0
144 INT177774 Transcription of PSEN1 1 0.33 0.09 0
145 INT354892 Negative_regulation of Psen2 1 0.37 0.95 0
146 INT193844 Positive_regulation of Protein_catabolism of Psen1 1 0.49 0.05 0
147 INT236037 Positive_regulation of Phosphorylation of APP 1 0.48 0.14 0
148 INT331463 Regulation of Gene_expression of PSEN2 1 0.04 0 0
149 INT234258 Negative_regulation of Phosphorylation of PSEN1 1 0.35 0.49 0
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