GO:0035335

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Name peptidyl-tyrosine dephosphorylation
Categary Process
Go Slim No
Go Link GO:0035335
Unique Molecular Interactions 245
Total Molecular Interactions 323
Total Single Events 2488
Pain Genes Associated 37

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for peptidyl-tyrosine dephosphorylation. They are ordered first by their pain relevance and then by number of times they were reported for peptidyl-tyrosine dephosphorylation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT125407 Binding of OPRL1 and PTPRM 1 0.03 0.72 4.67
2 INT34444 Binding of Oprl1 and Ptprg 4 0.03 0.18 4.58
3 INT76776 Binding of Pnoc and Ptprg 2 0.02 0 2.29
4 INT203044 Binding of PDCD1 and DTHD1 1 0.02 3.19 1.87
5 INT324926 Ptpro Positive_regulation of Bdkrb2 1 0.01 2.25 1.5
6 INT64259 Binding of Gtpbp4 and Ptprg 1 0.06 0 1.1
7 INT348175 Binding of NIDDM1 and PTPN22 1 0.01 2.36 0.99
8 INT203040 Binding of PDCD1 and PDCD1LG2 3 0.40 4.86 0.98
9 INT73461 PTPLA Positive_regulation of Transcription of TP53 1 0.06 0.99 0.96
10 INT111504 Pnoc Positive_regulation of Binding of Ptprg 1 0.01 0 0.96
11 INT73466 PTPLA Positive_regulation of Transcription of Hras1 1 0.21 0.98 0.95
12 INT73467 PTPLA Positive_regulation of Transcription of Myc 1 0.29 0.97 0.94
13 INT265566 Binding of PDE4D and PTPN5 1 0.03 0.81 0.85
14 INT320120 MTX1 Positive_regulation of PTEN 1 0.04 0.09 0.82
15 INT73462 PTPLA Regulation of Gene_expression of SART1 1 0.00 0.79 0.82
16 INT228255 Binding of Akt1 and Pten 2 0.43 1.78 0.8
17 INT72017 Binding of Adora2a and Ptprg 2 0.07 0 0.77
18 INT276213 Pten Regulation of Phosphorylation of Akt1 1 0.51 0.61 0.72
19 INT72689 Binding of Oprd1 and Ptprg 1 0.00 0.38 0.71
20 INT111506 Negative_regulation of Binding of Oprl1 and Ptprg 1 0.01 0 0.71
21 INT111505 Positive_regulation of Binding of Oprl1 and Ptprg 1 0.01 0 0.71
22 INT203046 Binding of PDCD1 and CD274 2 0.40 3.97 0.68
23 INT74728 Binding of Slc6a4 and Ptprj 1 0.01 0.48 0.68
24 INT299282 PTPN3 Negative_regulation of Positive_regulation of RPTOR 1 0.07 0.48 0.67
25 INT274871 Positive_regulation of Cbr2 Positive_regulation of Positive_regulation of Dusp6 1 0.02 0.72 0.67
26 INT74729 Binding of Mpz and Ptprj 1 0.06 0.15 0.66
27 INT253935 Binding of PTPLA and Trpv1 1 0.14 1.25 0.65
28 INT169293 PTPLA Positive_regulation of AKT1 1 0.10 0.15 0.64
29 INT329961 Binding of IL2RA and PTPN22 1 0.35 1.87 0.63
30 INT169285 PTPLA Positive_regulation of GRAP2 1 0.03 0.15 0.63
31 INT253137 Ptpn1 Negative_regulation of Ins1 1 0.19 4.11 0.63
32 INT169296 PTPLA Positive_regulation of MAPK3 1 0.10 0.15 0.63
33 INT169295 PTPLA Positive_regulation of MAPK8 1 0.10 0.15 0.63
34 INT5544 Ptpro Regulation of Syt17 1 0.05 0 0.6
35 INT169291 CNR1 Positive_regulation of Gene_expression of PTPLA 1 0.19 0.11 0.59
36 INT169298 TRPV1 Positive_regulation of Gene_expression of PTPLA 1 0.20 0.11 0.59
37 INT169292 Positive_regulation of CNR1 Positive_regulation of Gene_expression of PTPLA 1 0.19 0.11 0.59
38 INT203056 Binding of Cd274 and PDCD1LG2 1 0.13 1.61 0.57
39 INT203041 Binding of CD274 and PDCD1LG2 1 0.03 1.61 0.57
40 INT320121 Binding of PTEN and TNF 1 0.05 0.76 0.49
41 INT144932 DUSP5 Negative_regulation of TRPV1 1 0.00 0 0.48
42 INT83690 Binding of Oprm1 and Ptprg 1 0.00 0.08 0.48
43 INT321045 Anpep Positive_regulation of Protein_catabolism of Ptpn6 1 0.01 0.22 0.48
44 INT151485 Negative_regulation of Binding of Ptpn6 and Oprd1 1 0.00 0 0.47
45 INT151484 Binding of Ptpn6 and Oprd1 1 0.00 0 0.47
46 INT111509 Pnoc Positive_regulation of Binding of Ptprg 1 0.00 0 0.47
47 INT276218 Binding of Akt1 and Pten 1 0.26 0.08 0.46
48 INT52383 Binding of Gs and Ptprg 1 0.00 0.48 0.44
49 INT72016 Positive_regulation of Binding of Gnai2 and Ptprg 1 0.02 0 0.44
50 INT321047 Anpep Regulation of Negative_regulation of Ptpn6 1 0.01 0.25 0.43
51 INT77585 Binding of Htr1a and Ptprg 1 0.01 0 0.42
52 INT160046 INPPL1 Regulation of Gene_expression of PTEN 1 0.41 0.6 0.42
53 INT77584 Negative_regulation of Binding of Htr1a and Ptprg 1 0.01 0 0.42
54 INT160047 PTEN Regulation of Gene_expression of AKT1 1 0.33 0.6 0.42
55 INT160049 PTEN Regulation of Gene_expression of INPPL1 1 0.41 0.6 0.42
56 INT33380 Binding of PTPLA and NPL 1 0.23 0.27 0.41
57 INT72018 Binding of Gnai2 and Ptprg 1 0.01 0 0.41
58 INT66660 Pck1 Positive_regulation of Localization of Ptprg 1 0.07 0 0.4
59 INT129768 Binding of LYZ and PTPRC 1 0.34 0.87 0.37
60 INT257741 HRAS Negative_regulation of PTEN 1 0.15 1.06 0.35
61 INT257737 Positive_regulation of HRAS Negative_regulation of PTEN 1 0.17 1.07 0.35
62 INT328043 Binding of PTPRC and Enox2 1 0.00 0.88 0.34
63 INT328044 Positive_regulation of Binding of PTPRC and Enox2 1 0.00 0.89 0.34
64 INT328045 Binding of PTPRC and Tag 1 0.00 0.88 0.34
65 INT253147 Positive_regulation of Nr1h2 Negative_regulation of Positive_regulation of Ptpn1 1 0.17 0.61 0.33
66 INT274872 Positive_regulation of Cbr2 Positive_regulation of Dusp6 1 0.02 0.63 0.32
67 INT264504 Binding of CRYGD and PTPN22 1 0.04 0.42 0.31
68 INT203055 Binding of PDCD1 and Cd274 1 0.40 0.8 0.29
69 INT259936 CTLA4 Regulation of PTPN22 1 0.45 1.64 0.28
70 INT166094 Negative_regulation of CSK Negative_regulation of Positive_regulation of EGFR 1 0.02 0.33 0.28
71 INT333549 Binding of CTLA4 and PDCD1 1 0.36 1.2 0.27
72 INT222986 PTPRC Positive_regulation of SMN1 1 0.01 0.46 0.26
73 INT222975 PTPRC Positive_regulation of VIM 1 0.05 0.46 0.26
74 INT259937 Binding of CSK and PTPN22 1 0.21 1.69 0.25
75 INT261976 Binding of PDCD1 and SUGT1 1 0.00 1.3 0.25
76 INT250536 Ghrh Positive_regulation of Negative_regulation of Ptpn6 1 0.09 0 0.24
77 INT78296 Negative_regulation of Binding of Ptpra and Ldlr 1 0.22 0.25 0.24
78 INT60130 Binding of pcp and Ptprs 1 0.00 0 0.24
79 INT78295 Binding of Ptpra and Apoe 1 0.42 0.25 0.24
80 INT78294 Negative_regulation of Binding of Ptpra and Apoe 1 0.48 0.25 0.24
81 INT78291 Binding of Ptpra and Ldlr 1 0.20 0.25 0.24
82 INT165637 Ptpn6 Negative_regulation of Positive_regulation of Nfkb1 1 0.02 0.57 0.23
83 INT311613 Binding of Slc6a4 and Pten 1 0.24 0.32 0.21
84 INT72019 Binding of Gnaq and Ptprg 1 0.01 0 0.21
85 INT165636 Ptpn6 Regulation of Nfkb1 1 0.01 0.36 0.2
86 INT203848 Binding of Pten and Lna1 1 0.06 0.4 0.2
87 INT250537 Ptpn6 Negative_regulation of Igf1 1 0.08 0 0.2
88 INT224688 Pten Regulation of Akt1 1 0.04 1.12 0.19
89 INT237924 PTPN1 Regulation of Gene_expression of CFLAR 1 0.01 0.7 0.19
90 INT281477 Binding of Pten and Th 1 0.28 0.4 0.19
91 INT274832 Dusp6 Positive_regulation of Localization of Tlr4 1 0.00 0 0.19
92 INT338898 Binding of PECAM1 and PTPN11 1 0.04 0.38 0.19
93 INT289251 Ptpn11 Regulation of Il6 1 0.09 0.86 0.18
94 INT224680 Tgfb1 Negative_regulation of Pten 1 0.00 1.19 0.18
95 INT253127 Il6 Regulation of Gene_expression of Ptpn1 1 0.24 1.31 0.17
96 INT96559 Binding of PTPRC and KRT20 2 0.33 1.99 0.16
97 INT330388 Binding of PTPRC and TLR2 1 0.00 1.19 0.16
98 INT172674 Ptpn6 Negative_regulation of Gene_expression of Plat 1 0.02 1.3 0.16
99 INT34451 Binding of Itpr3 and Ptprg 1 0.03 0 0.15
100 INT208264 Park7 Negative_regulation of Pten 1 0.16 1.16 0.15
101 INT253154 TNF Positive_regulation of Ptpn1 1 0.73 0.91 0.15
102 INT153154 OPN1MW Regulation of PTPRF 1 0.03 0.51 0.14
103 INT222783 Binding of MR1 and PTPRC 1 0.00 0.46 0.14
104 INT277984 Negative_regulation of Epo Positive_regulation of Localization of Ptprc 1 0.02 0.77 0.12
105 INT34443 Negative_regulation of Binding of Trh and Ptprg 1 0.20 0.08 0.12
106 INT34445 Binding of Trh and Ptprg 1 0.23 0.08 0.12
107 INT256544 Pten Negative_regulation of Akt1 1 0.05 1.07 0.11
108 INT256545 Positive_regulation of Pten Negative_regulation of Akt1 1 0.05 1.07 0.11
109 INT338901 Binding of PECAM1 and PTPN6 1 0.03 0.18 0.1
110 INT267587 PTAFR Positive_regulation of Localization of PTPRC 1 0.00 2.04 0.09
111 INT133481 TNF Positive_regulation of Phosphorylation of PTEN 1 0.13 0.61 0.09
112 INT253300 Itgam Positive_regulation of Gene_expression of Ptprc 1 0.19 0.11 0.09
113 INT20959 Binding of PTPRC and Pak1 1 0.01 0.76 0.09
114 INT343794 Binding of F8 and PTPRC 1 0.00 0.69 0.09
115 INT259938 Binding of CTLA4 and PTPN22 1 0.36 0.85 0.08
116 INT91097 Ptprg Positive_regulation of Npr1 1 0.00 0.62 0.08
117 INT316792 Binding of HLA-DRB1 and Ptpn22 1 0.07 0.33 0.08
118 INT103810 Binding of PTPRC and RPL26 1 0.09 1.01 0.08
119 INT267017 Bdnf Positive_regulation of Dusp6 1 0.13 0.1 0.07
120 INT34448 Trh Negative_regulation of Negative_regulation of Ptprg 1 0.23 0 0.07
121 INT299291 Negative_regulation of PTPN3 Positive_regulation of Phosphorylation of SRC 1 0.07 0.12 0.07
122 INT231507 Binding of Ptprc and Tlr4 2 0.21 1.22 0.06
123 INT236363 Regulation of Binding of Ptprc and Tlr4 1 0.25 1.23 0.06
124 INT302164 PTEN Regulation of PIK3CD 1 0.16 1.13 0.06
125 INT236147 Binding of Ins1 and Ptpn1 2 0.03 1.29 0.05
126 INT179852 Binding of PTPRC and Ecm1 1 0.00 0 0.05
127 INT34447 Ptprg Positive_regulation of Itpr3 1 0.04 0 0.05
128 INT237351 Binding of Mtm1 and Gopc 1 0.19 0.17 0.05
129 INT295337 Egf Positive_regulation of Ptpn11 1 0.15 0.08 0.05
130 INT221815 PPARA Negative_regulation of PTEN 1 0.15 0.5 0.05
131 INT276386 Gtf3a Regulation of PTPN6 1 0.00 0.86 0.04
132 INT274833 Negative_regulation of Dusp6 Positive_regulation of Mapk1 1 0.01 0 0.04
133 INT227072 Binding of LTF and PTPRC 1 0.00 0.51 0.04
134 INT276392 Timp1 Regulation of PTPN6 1 0.02 0.87 0.04
135 INT336639 PTPRC Positive_regulation of Ecm1 1 0.00 0.62 0.04
136 INT274830 Tlr4 Positive_regulation of Gene_expression of Dusp6 1 0.00 0.06 0.03
137 INT253132 Il6 Positive_regulation of Gene_expression of Ptpn1 1 0.42 0.54 0.03
138 INT288199 Binding of Ptprc and Trav6-3 1 0.00 0.05 0.03
139 INT259935 CSK Positive_regulation of Negative_regulation of LCK 1 0.09 0.57 0.03
140 INT256549 Binding of Pten and Mtor 1 0.00 1.02 0.03
141 INT259940 CSK Positive_regulation of Phosphorylation of LCK 1 0.09 0.51 0.03
142 INT259939 Negative_regulation of Binding of CSK and PTPN22 1 0.19 0.62 0.03
143 INT329729 Binding of LCK and Fyn 1 0.00 0.21 0.03
144 INT337183 Binding of TLR3 and Positive_regulation of CD274 1 0.16 0.31 0.03
145 INT321785 IFN1@ Positive_regulation of Gene_expression of CD274 1 0.11 0.06 0.03
146 INT295349 Binding of Ptpn11 and Grb7 1 0.13 0.11 0.03
147 INT192678 PTEN Regulation of Dync1h1 1 0.02 0.5 0.03
148 INT274829 Tlr4 Regulation of Gene_expression of Dusp6 1 0.00 0.06 0.03
149 INT285580 Binding of PTPN11 and S100A8 1 0.05 0.2 0
150 INT336637 Binding of PTPRC and Fn1 1 0.00 0.32 0
151 INT321102 Binding of F5 and PTPRC 1 0.01 0.35 0
152 INT314397 Binding of Ptpn6 and Slc17a7 1 0.05 0 0
153 INT295338 Ptpn11 Regulation of Binding of Xpo1 1 0.02 0 0
154 INT304029 Binding of PTEN and TP53 1 0.35 0.62 0
155 INT278014 Ptprf Regulation of Localization of Gh 1 0.61 0.31 0
156 INT250659 Negative_regulation of PTEN Positive_regulation of Positive_regulation of PIK3CB 1 0.02 1.18 0
157 INT322546 Negative_regulation of PTPN6 Positive_regulation of Gene_expression of Cdkn1b 1 0.03 0.07 0
158 INT349219 PTPRC Positive_regulation of Gene_expression of SLC3A2 1 0.11 0.53 0
159 INT314393 Ptpn6 Regulation of 1190002H23Rik 1 0.01 0 0
160 INT267255 Bcl2 Positive_regulation of Gene_expression of Ptprj 1 0.04 0.63 0
161 INT295340 Binding of Ptpn11 and Fig4 1 0.04 0 0
162 INT296211 Binding of Ptprc and Tg(CAG-EGFP)D4Nagy 1 0.01 0.13 0
163 INT321718 Ins1 Regulation of Gene_expression of Pten 1 0.04 0.23 0
164 INT314402 Positive_regulation of Ptpn6 Regulation of 1190002H23Rik 1 0.02 0 0
165 INT194924 CD22 Positive_regulation of PTPN6 1 0.05 0.08 0
166 INT163585 Lep Positive_regulation of Gene_expression of Epm2a 1 0.03 0.14 0
167 INT314403 Ptpn6 Positive_regulation of Gpsm2 1 0.12 0.07 0
168 INT285908 AKT1 Regulation of Pten 1 0.01 0.53 0
169 INT283199 Binding of DMD and PTPRC 1 0.01 0.82 0
170 INT314374 Binding of Ptprc and Thy1 1 0.04 0.85 0
171 INT314398 Ptpn6 Regulation of Gene_expression of Ctbs 1 0.03 0 0
172 INT228288 Binding of ENG and Ptprc 1 0.06 0.25 0
173 INT261977 Binding of HLA-A and PDCD1 1 0.07 0.52 0
174 INT336640 Binding of PTPRC and Fbln1 1 0.01 0.32 0
175 INT249850 Binding of Ptprc and Cd34 1 0.13 0.48 0
176 INT263918 Binding of PTPRC and Cea 1 0.00 0.37 0
177 INT202599 Binding of IL2 and PTPN5 1 0.03 0.12 0
178 INT285581 Binding of CSK and S100A8 1 0.09 0.2 0
179 INT348723 ED Positive_regulation of PTEN 1 0.04 1.3 0
180 INT288981 Binding of DEFB1 and PTPN22 1 0.11 0 0
181 INT313885 XRCC1 Positive_regulation of Localization of PTEN 1 0.00 0.65 0
182 INT293802 PTEN Regulation of PIK3CG 1 0.03 0.07 0
183 INT322545 PTPN6 Positive_regulation of Gene_expression of Cdkn1b 1 0.03 0.07 0
184 INT351682 Fut1 Positive_regulation of PTEN 1 0.01 1.81 0
185 INT253144 Il6 Positive_regulation of Ptpn1 1 0.62 0.42 0
186 INT228285 Binding of Ptprc and Nt5e 1 0.06 0.25 0
187 INT223574 PTEN Negative_regulation of AKT1 1 0.06 0.56 0
188 INT304026 Binding of PIK3CG and PTEN 1 0.11 0.62 0
189 INT279534 Binding of CFH and PTPN11 1 0.02 2.54 0
190 INT223579 PTEN Negative_regulation of PIK3CG 1 0.18 0.56 0
191 INT295359 Ptpn11 Regulation of Phosphorylation of Grb7 1 0.10 0 0
192 INT245865 Binding of Cd34 and Ptprc 1 0.04 0 0
193 INT285910 Pten Regulation of AKT1 1 0.00 0.53 0
194 INT163584 Lep Positive_regulation of Epm2a 1 0.03 0.13 0
195 INT238114 Binding of CSK and SRC 1 0.07 0 0
196 INT314396 Binding of Ptpn6 and Slc17a6 1 0.05 0 0
197 INT241300 Binding of IGHG3 and PTPN11 1 0.01 1.47 0
198 INT182400 E2F2 Regulation of CDC25C 1 0.00 0.09 0
199 INT238115 Binding of CSK and STAT3 1 0.09 0.06 0
200 INT305350 Pten Regulation of Phosphorylation of Akt1 1 0.05 0.95 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for peptidyl-tyrosine dephosphorylation. They are ordered first by their pain relevance and then by number of times they were reported in peptidyl-tyrosine dephosphorylation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT21185 Binding of Ptprg 213 0.47 13.49 157.75
2 INT72011 Positive_regulation of Binding of Ptprg 42 0.50 2.72 39.89
3 INT21186 Negative_regulation of Binding of Ptprg 28 0.44 1.78 27.04
4 INT75421 Regulation of Binding of Ptprg 13 0.44 0.96 12.64
5 INT69029 Gene_expression of PTPRC 127 0.75 74.26 11.57
6 INT151168 Gene_expression of Pten 60 0.78 35.63 10.54
7 INT26248 Positive_regulation of Ptprg 12 0.40 1.42 9.48
8 INT119831 Gene_expression of PTEN 55 0.75 40.37 8.57
9 INT18736 Gene_expression of Ptpn6 19 0.59 4.44 8.06
10 INT9491 Positive_regulation of Ptpn6 11 0.51 2.33 7.32
11 INT76120 Gene_expression of Ptprc 102 0.59 30.42 7.02
12 INT32107 Gene_expression of PTPLA 14 0.47 8.06 6.76
13 INT50975 Localization of Ptpn6 8 0.65 2.64 5.7
14 INT245593 Gene_expression of PTPN3 32 0.38 10.68 5.09
15 INT203050 Binding of PDCD1 12 0.48 12.93 4.5
16 INT21188 Negative_regulation of Ptprg 9 0.37 0.62 4.16
17 INT276198 Positive_regulation of Pten 1 0.52 5.02 3.88
18 INT11261 Positive_regulation of PTPLA 3 0.50 4.4 3.74
19 INT28389 Negative_regulation of Ptpra 5 0.37 0.4 3.69
20 INT151171 Positive_regulation of Pten 20 0.55 13.3 3.54
21 INT78284 Positive_regulation of PTPRC 40 0.49 27.17 3.45
22 INT6339 Negative_regulation of Ptpn6 6 0.14 0.71 3.44
23 INT167647 Binding of PTPN5 2 0.32 3.21 3.38
24 INT208291 Negative_regulation of Pten 2 0.44 5.42 3.36
25 INT64 Regulation of Ptpn6 12 0.14 2.45 3.17
26 INT192676 Binding of PTEN 14 0.46 10.58 3.06
27 INT202606 Regulation of PTPN5 1 0.26 3.92 3.04
28 INT21187 Regulation of Ptprg 7 0.39 0.38 2.93
29 INT184477 Negative_regulation of Pten 27 0.59 15.61 2.8
30 INT246978 Binding of PTPLA 3 0.18 3.62 2.79
31 INT161310 Negative_regulation of LCK 17 0.42 8.75 2.74
32 INT119383 Gene_expression of Pten 11 0.59 10.33 2.73
33 INT321018 Protein_catabolism of Ptpn6 1 0.14 0.52 2.73
34 INT203048 Gene_expression of PDCD1 13 0.78 8.5 2.62
35 INT187454 Binding of Ptprc 34 0.38 9.66 2.54
36 INT119838 Positive_regulation of PTEN 25 0.67 21.71 2.5
37 INT230758 Positive_regulation of Gene_expression of PTPRC 11 0.49 6.04 2.45
38 INT9721 Gene_expression of Ptpra 3 0.26 5.97 2.38
39 INT203049 Negative_regulation of PDCD1 6 0.43 7.15 2.36
40 INT231573 Binding of PTPN22 5 0.44 7.94 2.33
41 INT203047 Gene_expression of CD274 16 0.52 12.32 2.21
42 INT179885 Regulation of PTEN 8 0.26 11.88 2.18
43 INT137629 Binding of Ptpn6 10 0.30 0.42 2.15
44 INT49433 Binding of PTPRM 2 0.02 0.26 2.15
45 INT321023 Positive_regulation of Localization of Ptpn6 1 0.07 0.27 2.15
46 INT122671 Positive_regulation of LCK 4 0.13 2.69 2.14
47 INT224615 Negative_regulation of Gene_expression of Pten 7 0.59 2.99 2.09
48 INT276201 Phosphorylation of Pten 1 0.61 1.31 2.08
49 INT49432 Gene_expression of PTPRM 2 0.04 0.27 1.87
50 INT202602 Positive_regulation of PTPN5 4 0.29 3.34 1.83
51 INT15556 Positive_regulation of Epm2a 3 0.44 1.53 1.69
52 INT38266 Localization of PTPRC 30 0.68 17.05 1.68
53 INT207100 Gene_expression of Ptpn1 13 0.73 8.13 1.68
54 INT276171 Positive_regulation of Gene_expression of Pten 3 0.52 7.24 1.64
55 INT206528 Negative_regulation of Gene_expression of Ptprc 8 0.34 3.91 1.61
56 INT22329 Gene_expression of Ptprc 36 0.66 15.84 1.59
57 INT151169 Positive_regulation of Gene_expression of Pten 15 0.45 12.88 1.53
58 INT274884 Positive_regulation of Dusp6 1 0.07 2.08 1.52
59 INT29856 Negative_regulation of Positive_regulation of Ptpn6 3 0.38 1.24 1.47
60 INT265567 Localization of PTPN5 1 0.49 1.39 1.47
61 INT128478 Positive_regulation of Ptprc 26 0.44 8.1 1.45
62 INT228249 Binding of Pten 7 0.48 3.26 1.45
63 INT122672 Regulation of Positive_regulation of LCK 1 0.06 1.15 1.44
64 INT281470 Regulation of Gene_expression of Pten 4 0.39 1.13 1.42
65 INT276196 Positive_regulation of Phosphorylation of Pten 1 0.38 0.19 1.41
66 INT178898 Gene_expression of PTPN5 4 0.38 3.06 1.4
67 INT304045 Transcription of PTEN 2 0.51 4.12 1.4
68 INT271464 Transcription of Ptpro 1 0.02 0.95 1.4
69 INT274892 Gene_expression of Dusp6 1 0.08 1.81 1.4
70 INT276181 Negative_regulation of Gene_expression of Pten 1 0.44 2.48 1.37
71 INT65121 Negative_regulation of Ptpro 1 0.02 0.97 1.36
72 INT316787 Binding of Ptpn22 1 0.29 3.61 1.29
73 INT90771 Positive_regulation of Ptprc 20 0.48 8.43 1.27
74 INT74254 Binding of PTPRC 16 0.36 8.37 1.27
75 INT37253 Negative_regulation of PTPRC 12 0.37 6.13 1.26
76 INT26372 Localization of Ptprg 2 0.10 0.09 1.24
77 INT245598 Positive_regulation of PTPN3 3 0.34 1.13 1.23
78 INT119827 Gene_expression of PTPN11 31 0.75 24.21 1.22
79 INT206515 Regulation of Gene_expression of Ptprc 6 0.39 3.4 1.22
80 INT190014 Regulation of Pten 8 0.62 6.03 1.2
81 INT119832 Positive_regulation of Gene_expression of PTEN 12 0.49 7.12 1.19
82 INT12435 Binding of Ptprs 1 0.06 0 1.17
83 INT314388 Positive_regulation of Gene_expression of Ptpn6 3 0.11 0.05 1.15
84 INT321016 Regulation of Positive_regulation of Ptpn6 1 0.05 0.05 1.15
85 INT321020 Regulation of Protein_catabolism of Ptpn6 1 0.06 0.05 1.12
86 INT62237 Gene_expression of Ptprf 2 0.65 1.63 1.08
87 INT33884 Gene_expression of Ptprg 3 0.59 0.83 1.07
88 INT236138 Negative_regulation of Ptpn1 10 0.55 5.83 1.04
89 INT147464 Binding of Ptprc 13 0.36 15.18 0.98
90 INT248588 Gene_expression of LCK 9 0.28 4.9 0.98
91 INT253114 Positive_regulation of Ptpn1 9 0.44 5.48 0.96
92 INT9722 Negative_regulation of Gene_expression of Ptpra 1 0.15 0.8 0.96
93 INT274888 Negative_regulation of Dusp6 1 0.06 1.82 0.93
94 INT294150 Regulation of Gene_expression of PTPRC 6 0.32 3.3 0.88
95 INT276177 Regulation of Gene_expression of Pten 1 0.34 1.51 0.84
96 INT161311 Positive_regulation of Negative_regulation of LCK 2 0.45 0.74 0.83
97 INT25800 Negative_regulation of Negative_regulation of Ptprg 2 0.06 0.22 0.82
98 INT245596 Positive_regulation of Gene_expression of PTPN3 5 0.25 0.92 0.79
99 INT253103 Negative_regulation of Gene_expression of Ptpn1 1 0.55 2.56 0.79
100 INT193313 Gene_expression of PDCD1LG2 7 0.57 3.52 0.76
101 INT119834 Phosphorylation of PTEN 12 0.79 6.78 0.75
102 INT250144 Positive_regulation of CD274 11 0.47 5.77 0.72
103 INT122670 Negative_regulation of Positive_regulation of LCK 1 0.06 0.58 0.72
104 INT42722 Negative_regulation of Ptpn11 1 0.21 0 0.71
105 INT119836 Positive_regulation of Gene_expression of PTPN11 5 0.67 3.44 0.69
106 INT253934 Positive_regulation of Binding of PTPLA 1 0.16 0.51 0.69
107 INT276199 Binding of Pten 2 0.30 0.4 0.67
108 INT44478 Negative_regulation of PTEN 32 0.57 27.45 0.63
109 INT321017 Negative_regulation of Protein_catabolism of Ptpn6 1 0.08 0.19 0.63
110 INT274881 Regulation of Dusp6 1 0.04 0.9 0.63
111 INT329708 Transcription of LCK 1 0.04 1.54 0.63
112 INT276179 Regulation of Pten 1 0.46 0.81 0.63
113 INT6168 Negative_regulation of Regulation of Ptpn6 1 0.15 0 0.62
114 INT60057 Negative_regulation of Localization of Ptpn6 1 0.31 0.39 0.62
115 INT261979 Positive_regulation of PDCD1 4 0.49 6.95 0.61
116 INT274885 Negative_regulation of Gene_expression of Dusp6 1 0.04 0.89 0.6
117 INT109505 Regulation of Ptprc 3 0.32 2.45 0.58
118 INT161322 Localization of PTEN 9 0.73 5.65 0.57
119 INT203051 Positive_regulation of Gene_expression of PDCD1 2 0.50 2.08 0.57
120 INT169304 Phosphorylation of PTPLA 1 0.23 0.18 0.57
121 INT274880 Negative_regulation of Positive_regulation of Dusp6 1 0.04 0.89 0.52
122 INT74724 Regulation of Ptprj 2 0.05 0.35 0.51
123 INT143131 Regulation of Ptprc 4 0.27 2.56 0.5
124 INT176146 Positive_regulation of Localization of PTEN 3 0.36 1.69 0.5
125 INT74725 Localization of Ptprj 1 0.14 0.15 0.5
126 INT163579 Gene_expression of Epm2a 2 0.06 1.15 0.49
127 INT253098 Positive_regulation of Gene_expression of Ptpn1 3 0.65 2.05 0.48
128 INT276174 Regulation of Negative_regulation of Pten 1 0.34 0.63 0.47
129 INT144943 Positive_regulation of DUSP5 1 0.00 0 0.47
130 INT267615 Positive_regulation of Localization of PTPRC 3 0.01 3.41 0.46
131 INT151482 Negative_regulation of Binding of Ptpn6 1 0.00 0 0.46
132 INT203052 Regulation of PDCD1 1 0.39 0.79 0.45
133 INT21183 Negative_regulation of Regulation of Ptprg 1 0.37 0.08 0.44
134 INT203053 Localization of PDCD1 1 0.70 1.55 0.44
135 INT119826 Positive_regulation of PTPN11 2 0.45 2.67 0.43
136 INT33885 Positive_regulation of Gene_expression of Ptprg 1 0.02 0 0.43
137 INT276180 Positive_regulation of Negative_regulation of Pten 1 0.35 0.89 0.43
138 INT321009 Regulation of Gene_expression of Ptpn6 1 0.05 0.3 0.43
139 INT187463 Positive_regulation of Gene_expression of Ptprc 9 0.44 2.8 0.42
140 INT276202 Negative_regulation of Protein_catabolism of Pten 1 0.32 0.78 0.42
141 INT241304 Regulation of Transcription of PTPN11 3 0.43 4.49 0.41
142 INT276204 Protein_catabolism of Pten 1 0.75 0.77 0.41
143 INT321429 Positive_regulation of Gene_expression of PTPN6 1 0.03 1.78 0.41
144 INT245599 Regulation of Gene_expression of PTPN3 1 0.22 0.57 0.41
145 INT203816 Localization of Pten 4 0.75 1.37 0.4
146 INT189030 Phosphorylation of PTPN3 3 0.31 1.17 0.39
147 INT55723 Regulation of Regulation of Ptprs 1 0.26 0 0.39
148 INT55722 Regulation of Ptprs 1 0.26 0 0.39
149 INT168101 Positive_regulation of PTPRF 2 0.45 1.04 0.37
150 INT158592 Negative_regulation of CSK 2 0.19 0.43 0.36
151 INT207088 Localization of Ptpn1 2 0.35 1.48 0.36
152 INT151167 Phosphorylation of Pten 3 0.72 1.69 0.35
153 INT245591 Negative_regulation of Gene_expression of PTPN3 2 0.21 0.44 0.35
154 INT151166 Positive_regulation of Phosphorylation of Pten 2 0.40 1.54 0.35
155 INT329707 Negative_regulation of Transcription of LCK 1 0.04 0.9 0.35
156 INT231497 Negative_regulation of Binding of Ptprc 2 0.34 0.99 0.33
157 INT281469 Transcription of Pten 2 0.72 1.12 0.32
158 INT281474 Regulation of Transcription of Pten 1 0.62 0.35 0.32
159 INT263819 Regulation of Gene_expression of PTEN 1 0.25 0.63 0.32
160 INT231658 Regulation of Epm2a 1 0.03 0.5 0.31
161 INT261363 Negative_regulation of Gene_expression of Ptprg 1 0.01 0.84 0.31
162 INT321822 Positive_regulation of Gene_expression of CD274 7 0.34 2.87 0.3
163 INT147463 Positive_regulation of Binding of Ptprc 2 0.35 0.95 0.3
164 INT248785 Regulation of Gene_expression of PTPLA 1 0.07 0.06 0.29
165 INT245595 Localization of PTPN3 1 0.39 0.67 0.29
166 INT245592 Regulation of PTPN3 3 0.22 0.88 0.28
167 INT212615 Localization of PTPRF 2 0.68 0.34 0.28
168 INT271459 Positive_regulation of Ptpro 1 0.01 1.09 0.27
169 INT274883 Positive_regulation of Gene_expression of Dusp6 1 0.07 0.39 0.27
170 INT133488 Negative_regulation of Phosphorylation of PTEN 4 0.41 1.88 0.26
171 INT227102 Gene_expression of Mtm1 2 0.77 9.58 0.26
172 INT80059 Negative_regulation of Ptprc 8 0.41 1.85 0.25
173 INT187465 Localization of Ptprc 8 0.62 3.71 0.25
174 INT252757 Negative_regulation of PTPN6 4 0.10 0.74 0.25
175 INT187460 Transcription of Ptprc 2 0.44 0.51 0.25
176 INT274876 Positive_regulation of Positive_regulation of Dusp6 1 0.04 0.49 0.25
177 INT278159 Regulation of LCK 1 0.04 0.98 0.22
178 INT278161 Localization of LCK 1 0.27 0.98 0.22
179 INT245156 Negative_regulation of Gene_expression of PTPRC 4 0.41 0.89 0.21
180 INT245597 Positive_regulation of Localization of PTPN3 1 0.34 0.07 0.21
181 INT241302 Transcription of PTPN11 3 0.67 2.81 0.2
182 INT321425 Gene_expression of PTPN6 1 0.03 0.89 0.2
183 INT224616 Regulation of Negative_regulation of Pten 1 0.13 1.21 0.18
184 INT289228 Localization of Ptpn11 1 0.15 0.87 0.18
185 INT208524 Regulation of PTPRC 7 0.11 3.22 0.16
186 INT183242 Negative_regulation of Gene_expression of PTEN 6 0.55 3.81 0.16
187 INT189039 Negative_regulation of PTPN3 3 0.21 1.01 0.16
188 INT280906 Negative_regulation of Ptprc 2 0.15 2.26 0.16
189 INT321820 Localization of CD274 1 0.07 0.49 0.16
190 INT152889 Transcription of PTPRC 1 0.69 0.31 0.16
191 INT187456 Regulation of Binding of Ptprc 1 0.29 0.51 0.15
192 INT96224 Positive_regulation of Ptprf 1 0.11 0.36 0.14
193 INT237340 Positive_regulation of Mtm1 1 0.60 1.52 0.14
194 INT175046 Negative_regulation of Gene_expression of Ptprc 2 0.30 0.8 0.13
195 INT245594 Positive_regulation of Positive_regulation of PTPN3 1 0.23 0.42 0.13
196 INT239373 Positive_regulation of Positive_regulation of PTEN 3 0.25 4.98 0.12
197 INT184029 Binding of Ptpn11 2 0.19 0.18 0.12
198 INT278162 Negative_regulation of Gene_expression of LCK 1 0.15 0.64 0.12
199 INT275204 Binding of LCK 2 0.12 1.19 0.11
200 INT187313 Regulation of PTPRF 1 0.01 0 0.11
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