GO:0035426

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Name extracellular matrix-cell signaling
Categary Process
Go Slim No
Go Link GO:0035426
Unique Molecular Interactions 18
Total Molecular Interactions 29
Total Single Events 120
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for extracellular matrix-cell signaling. They are ordered first by their pain relevance and then by number of times they were reported for extracellular matrix-cell signaling. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT120848 Sp6 Positive_regulation of Gene_expression of Ndp 1 0.14 0.52 0.74
2 INT61798 Binding of NDP and POMC 2 0.22 0 0.66
3 INT71110 Binding of MC1R and NDP 1 0.10 0 0.57
4 INT147404 NDP Positive_regulation of MC1R 1 0.22 0.25 0.45
5 INT61799 Negative_regulation of Binding of NDP and POMC 1 0.20 0 0.41
6 INT335888 Lrp5 Negative_regulation of Gene_expression of Tph1 1 0.22 0.15 0.21
7 INT254433 Binding of Lrp5 and Sost 2 0.39 1.51 0.03
8 INT254434 Binding of Lrp5 and Best1 3 0.29 2.53 0
9 INT342385 Positive_regulation of Binding of Lrp5 and Vdr 1 0.53 0.98 0
10 INT302322 Negative_regulation of Binding of Lrp5 and SOST 1 0.16 0.26 0
11 INT297848 Binding of Fzd4 and Ndp 1 0.04 1.19 0
12 INT297855 Binding of Ndp and Wnt1 1 0.38 1.18 0
13 INT342381 Binding of Lrp5 and Vdr 1 0.55 0.97 0
14 INT342382 Binding of Car1 and Lrp5 1 0.40 0.9 0
15 INT302319 Binding of Lrp5 and SOST 1 0.18 0.26 0
16 INT335891 Binding of Dkk1 and Lrp5 1 0.39 0.57 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for extracellular matrix-cell signaling. They are ordered first by their pain relevance and then by number of times they were reported in extracellular matrix-cell signaling. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT64523 Binding of Ndp 10 0.33 2.72 7.29
2 INT69944 Positive_regulation of Ndp 7 0.38 4.81 5.6
3 INT85301 Gene_expression of Ndp 6 0.52 4.19 4.5
4 INT61802 Binding of NDP 6 0.28 0 1.85
5 INT61800 Negative_regulation of Binding of NDP 3 0.24 0 1.14
6 INT64525 Negative_regulation of Binding of Ndp 4 0.10 0.31 1.03
7 INT105070 Localization of Ndp 1 0.57 0.93 0.91
8 INT85300 Regulation of Ndp 1 0.23 0.42 0.79
9 INT71114 Regulation of NDP 1 0.12 0 0.61
10 INT74100 Negative_regulation of Ndp 1 0.33 0 0.53
11 INT147405 Positive_regulation of Transcription of NDP 1 0.20 0.27 0.45
12 INT147406 Transcription of NDP 1 0.28 0.26 0.44
13 INT61801 Negative_regulation of NDP 1 0.23 0 0.41
14 INT297804 Regulation of Lrp5 6 0.60 2.31 0.27
15 INT254427 Binding of Lrp5 10 0.48 5.43 0.26
16 INT254429 Negative_regulation of Lrp5 4 0.57 1.95 0.18
17 INT254426 Gene_expression of Lrp5 5 0.67 3.28 0.06
18 INT319131 Positive_regulation of Lrp5 1 0.43 0.36 0.03
19 INT297757 Transcription of Lrp5 2 0.68 0.82 0
20 INT297820 Regulation of Transcription of Lrp5 2 0.44 0.83 0
21 INT297823 Gene_expression of Ndp 1 0.63 2.51 0
22 INT297821 Regulation of Fzd4 1 0.03 0.57 0
23 INT297789 Negative_regulation of Negative_regulation of Ndp 1 0.41 0.97 0
24 INT342375 Positive_regulation of Binding of Lrp5 1 0.46 0.85 0
25 INT297791 Transcription of Fzd4 1 0.06 0.58 0
26 INT258449 Positive_regulation of NDP 1 0.00 0.81 0
27 INT297836 Negative_regulation of Ndp 1 0.41 1.8 0
28 INT109121 Positive_regulation of Ndp 1 0.11 0.08 0
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